Predecessor_CID,Predecessor_Name,Successor_CID,Successor_Name,Transformation,Biosystem,Enzyme,Source_ID,Source_CID,Source,Source_Description,Dataset_DOI,Dataset_Description,Evidence_ID,Evidence_Description,Comment
13450,Terbutryn,110189337,t-Butylcarboxyl-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,110189337,t-Butylcarboxyl-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,13019211,Deethylterbutryne,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,13019211,Deethylterbutryne,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,13450,Terbutryn,none,NA,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
13450,Terbutryn,135495928,Terbutylazine-2-hydroxy,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",
13450,Terbutryn,135495928,Terbutylazine-2-hydroxy,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,135495928,Terbutylazine-2-hydroxy,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,135612794,Terbutylazine-desethyl-2-hydroxy,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",
13450,Terbutryn,14251376,S-Demethylterbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,14251376,S-Demethylterbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,146035700,N-ethylcarboxyl-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",
13450,Terbutryn,146035700,N-ethylcarboxyl-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,146035700,N-ethylcarboxyl-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,146035701,t-Butylhydroxy-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",
13450,Terbutryn,146035701,t-Butylhydroxy-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:678607,PMID:678607,
13450,Terbutryn,146035701,t-Butylhydroxy-terbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 323",
13450,Terbutryn,146035703,S-Demethyl-desethylterbutryn,mammalian metabolism,Mammal,NA,1525,13450,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",
1486,"2,4-Dichlorophenoxyacetic acid",1110,Succinic acid,bacterial metabolism,Bacteria,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 196",
1486,"2,4-Dichlorophenoxyacetic acid",1486,"2,4-Dichlorophenoxyacetic acid",none,NA,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
1486,"2,4-Dichlorophenoxyacetic acid",151029,"2,5-Dichloro-4-hydroxyphenoxyacetic acid",plant metabolism,Plant,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 193",
1486,"2,4-Dichlorophenoxyacetic acid",69018092,"2,4-Dichloro-5-hydroxyphenoxyacetic acid",plant metabolism,Plant,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 193",
1486,"2,4-Dichlorophenoxyacetic acid",8449,"2,4-Dichlorophenol",animal metabolism,Animal,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11170571,PMID:11170571,
1486,"2,4-Dichlorophenoxyacetic acid",8449,"2,4-Dichlorophenol",bacterial metabolism,Bacteria,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 196",
1486,"2,4-Dichlorophenoxyacetic acid",8449,"2,4-Dichlorophenol",plant metabolism,Plant,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Steen RC et al; Weed Res 14: 23 (1974) as cited in USEPA; Ambient Water QualityCriteria Doc: 2,4-Dichlorophenol p.C-9 (1980) EPA 440/5-80-042",
15625,"2,3,7,8-Tetrachlorodibenzo-P-dioxin",1486,"2,4-Dichlorophenoxyacetic acid",mammalian metabolism,Mammal,NA,202,1486,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3672528,PMID:3672528,
16183,"2,6-Dichlorobenzamide",16183,"2,6-Dichlorobenzamide",none,NA,NA,2728,16183,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
16183,"2,6-Dichlorobenzamide",18006765,"2,6-Dichloro-4-hydroxybenzamide",plant metabolism,Plant,NA,2728,16183,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 573",
16183,"2,6-Dichlorobenzamide",186076,"2,6-Dichloro-3-hydroxybenzamide",plant metabolism,Plant,NA,2728,16183,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 573",
16183,"2,6-Dichlorobenzamide",5758,"2,6-Dichlorobenzoic acid",plant metabolism,Plant,NA,2728,16183,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-15",
22206,Terbuthylazine,135495928,Terbutylazine-2-hydroxy,mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,108201,Desethylterbuthylazine,mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin CDS, ed. Terbuthylazine (5915-41-3). In: The e-Pesticide Manual, Version 2.2 (2002). Surrey UK, British Crop Protection Council.",
22206,Terbuthylazine,108201,Desethylterbuthylazine,mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,108201,Desethylterbuthylazine,"in vitro (rats, pigs, humans) metabolism","Rat, pig, human (in vitro)",NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
22206,Terbuthylazine,118372,"6-Chloro-1,3,5-triazine-2,4(1H,3H)-dione",mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,12584,Ammelide,identified in urine and feces,,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.13 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,135408770,Ammeline,identified in urine and feces,,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.13 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,135438601,"4-Amino-6-chloro-1,3,5-triazin-2-ol",mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,13878,Deisopropylatrazine,"in vitro (rats, pigs, humans) metabolism","Rat, pig, human (in vitro)",NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
22206,Terbuthylazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Reregistration Eligibility Decision (RED) Database for Terbuthylazine (5915-41-3). EPA 738-R-95-005 p.12 (March 1995). Available from, as of October 11, 2012: http://www.epa.gov/pesticides/reregistration/status.htm",
22206,Terbuthylazine,22206,Terbuthylazine,none,NA,NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
22206,Terbuthylazine,779516,"2-[[4-Chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino]-2-methylpropan-1-ol","in vitro (rats, pigs, humans) metabolism","Rat, pig, human (in vitro)",NA,6148,22206,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,135408770,Ammeline,mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 174",
2256,Atrazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",
2256,Atrazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 535",
2256,Atrazine,13878,Deisopropylatrazine,human metabolism,Human,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,13878,Deisopropylatrazine,in vitro mammalian metabolism,Mammal (in vitro),NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",
2256,Atrazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 535",
2256,Atrazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",human metabolism,Human,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian fetal metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:23958493,PMID:23958493,
2256,Atrazine,135398733,Hydroxyatrazine,avian metabolism,Bird,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 527",
2256,Atrazine,135510207,Atrazine-desethyl-2-hydroxy,avian metabolism,Bird,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 527",
2256,Atrazine,15818023,"2-Chloro-4-(ethylamino)-6-(1-methyl-2-hydroxyethylamino)-1,3,5-triazine",in vitro mammalian metabolism,Mammal (in vitro),NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,2256,Atrazine,none,NA,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
2256,Atrazine,22563,Deethylatrazine,mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",
2256,Atrazine,22563,Deethylatrazine,mammalian metabolism,Mammal,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 535",
2256,Atrazine,22563,Deethylatrazine,bacterial metabolism,Bacteria,NA,2672,22563,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Behki RM and Khan Su; J Agric Food Chem 34 (4): 748-9 (1986),
2256,Atrazine,22563,Deethylatrazine,avian metabolism,Bird,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 527",
2256,Atrazine,22563,Deethylatrazine,human metabolism,Human,NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,22563,Deethylatrazine,in vitro mammalian metabolism,Mammal (in vitro),NA,413,2256,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: http://monographs.iarc.fr/ENG/Classification/index.php, p. V73 84 (1999)",
2256,Atrazine,22563,Deethylatrazine,fungal metabolism,Fungi,NA,2672,22563,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8967773,PMID:8967773,
2256,Atrazine,22563,Deethylatrazine,"mammalian, bacterial, plant metabolism","Mammal, bacteria, plant",NA,2672,22563,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA; Revised Toxicology Chapter; Interim Reregistration Eligibility Decision (IRED) for Atrazine (1912-24-9). Available from, as of Nov 20, 2003: http://www.epa.gov/oppsrrd1/reregistration/atrazine/",
2256,Atrazine,22563,Deethylatrazine,metabolism,NA,NA,2672,22563,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:512229,PMID:512229,
22563,Deethylatrazine,22563,Deethylatrazine,none,NA,NA,2672,22563,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
2328,Bentazone,2328,Bentazone,none,NA,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
2328,Bentazone,92361,6-Hydroxybentazone,mammalian metabolism,Mammal,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.37 (2012). Available from, as of October 27, 2017: http://www.who.int/foodsafety/publications/jmpr-monographs/en/",
2328,Bentazone,92361,6-Hydroxybentazone,plant metabolism,Plant,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gronwald JW, Connelly JA; Pestic Biochem Physiol 40 (3): 284-94 (1991)",
2328,Bentazone,92361,6-Hydroxybentazone,plant metabolism,Plant,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 61",
2328,Bentazone,92361,6-Hydroxybentazone,plant metabolism,Plant,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.80 (2012). Available from, as of October 27, 2017: http://www.who.int/foodsafety/publications/jmpr-monographs/en/",
2328,Bentazone,92361,6-Hydroxybentazone,soybean metabolism,Soybean,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Leah JM et al  Pestic Biochem Physiol 39 (3): 232-9 (1991),
2328,Bentazone,92361,6-Hydroxybentazone,soybean metabolism,Soybean,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Leah JM et al  Pestic Sci 34 (1): 81-7 (1992),
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",mammalian metabolism,Mammal,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.37 (2012). Available from, as of October 27, 2017: http://www.who.int/foodsafety/publications/jmpr-monographs/en/",
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",plant metabolism,Plant,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 61",
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",plant metabolism,Plant,NA,3430,2328,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.80 (2012). Available from, as of October 27, 2017: http://www.who.int/foodsafety/publications/jmpr-monographs/en/",
243,Benzoic acid,100001,N-Benzoylhistidine,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,10868697,(2S)-5-Amino-2-benzamido-5-oxopentanoic acid,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,115145,Benzoyl glucuronide,mammalian metabolism,Mammal,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety's Concise International Chemical Assessment  Documents. Number 26: Benzoic acid and Sodium Benzoate (2000). Available from, as of March 24, 2005: http://www.inchem.org/pages/cicads.html",
243,Benzoic acid,115145,Benzoyl glucuronide,mammalian metabolism,Mammal,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 407",
243,Benzoic acid,115145,Benzoyl glucuronide,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,115145,Benzoyl glucuronide,transformation,NA,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cosmetic Ingredient Review Expert Panel International Journal of Toxicology 20 (suppl. 3): 23-50 (2001),
243,Benzoic acid,12314096,Benzoyl-beta-D-glucoside,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,135,4-Hydroxybenzoic acid,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-8",
243,Benzoic acid,17812554,2-Amino-2-benzoyl-5-(diaminomethylideneamino)pentanoic acid,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,184849,"N(2),N(5)-Dibenzoyl-L-ornithine",avian metabolism,Bird,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"LaDu, B.N., H.G. Mandel, and E.L. Way. Fundamentals of Drug Metabolism and Disposition. Baltimore: Williams and Wilkins, 1971., p. 195",
243,Benzoic acid,240,Benzaldehyde,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,243,Benzoic acid,none,NA,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
243,Benzoic acid,439689,Benzoylagmatine,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",
243,Benzoic acid,464,Hippuric acid,mammalian metabolism,Mammal,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 407",
243,Benzoic acid,464,Hippuric acid,animal metabolism,Animal,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; IUCLID Dataset, Benzoic acid (65-85-0) (2000 CD-ROM edition). Available from, as of March 22, 2005: http://esis.jrc.ec.europa.eu/",
243,Benzoic acid,464,Hippuric acid,human metabolism,Human,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cosmetic Ingredient Review Expert Panel International Journal of Toxicology 20 (suppl. 3): 23-50 (2001),
243,Benzoic acid,464,Hippuric acid,human metabolism,Human,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety's Concise International Chemical Assessment  Documents. Number 26: Benzoic acid and Sodium Benzoate (2000). Available from, as of March 24, 2005: http://www.inchem.org/pages/cicads.html",
243,Benzoic acid,464,Hippuric acid,transformation,NA,NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cosmetic Ingredient Review Expert Panel International Journal of Toxicology 20 (suppl. 3): 23-50 (2001),
243,Benzoic acid,7420,3-Hydroxybenzoic acid,animal and plant metabolism,"Animal, plant",NA,704,243,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-8",
25429,Carbendazim,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,mammalian metabolism,Mammal,NA,6581,25429,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3765661,PMID:3765661,
25429,Carbendazim,13624,2-Aminobenzimidazole,mammalian metabolism,Mammal,NA,6581,25429,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3765661,PMID:3765661,
25429,Carbendazim,13624,2-Aminobenzimidazole,plant metabolism,Plant,NA,6581,25429,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin, C.D.S. (ed.). The Pesticide Manual - World Compendium. 10th ed. Surrey, UK: The British Crop Protection Council, 1994., p. 150",
25429,Carbendazim,25429,Carbendazim,none,NA,NA,6581,25429,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
28780,Benomyl,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Clayton, G.D., F.E. Clayton (eds.) Patty's Industrial Hygiene and Toxicology. Volumes 2A, 2B, 2C, 2D, 2E, 2F: Toxicology. 4th ed. New York, NY: John Wiley & Sons Inc., 1993-1994., p. 3345",
28780,Benomyl,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 249",
28780,Benomyl,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO Environ Health Criteria 148: Benomyl p.50 (1993),
28780,Benomyl,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,avian metabolism,Bird,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 30",
28780,Benomyl,13624,2-Aminobenzimidazole,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-26",
28780,Benomyl,13624,2-Aminobenzimidazole,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 30",
28780,Benomyl,25429,Carbendazim,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 51",
28780,Benomyl,25429,Carbendazim,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 29",
28780,Benomyl,25429,Carbendazim,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 30",
28780,Benomyl,12526523,2-Amino-N-butylbenzimidazole-1-carboxamide,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-26",
28780,Benomyl,162636,2-Amino-1H-benzo[d]imidazol-5-ol,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO Environ Health Criteria 148: Benomyl p.50 (1993),
28780,Benomyl,18006547,(2-Amino-6-hydroxyphenyl)urea,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,18006547,(2-Amino-6-hydroxyphenyl)urea,photolysis,NA,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,28780,Benomyl,none,NA,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
28780,Benomyl,3082533,5-Hydroxybenzimidazole,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,3082533,5-Hydroxybenzimidazole,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO Environ Health Criteria 148: Benomyl p.50 (1993),
28780,Benomyl,584119,1H-Benzoimidazol-4-ol,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,610002,Methyl (7-hydroxy-1H-benzimidazol-2-yl)carbamate,mammalian metabolism,Mammal,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO Environ Health Criteria 148: Benomyl p.50 (1993),
28780,Benomyl,7243,O-Phenylenediamine,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,7243,O-Phenylenediamine,photolysis,NA,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,72913,2-Aminobenzonitrile,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
28780,Benomyl,72913,2-Aminobenzonitrile,plant metabolism,Plant,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 29",
28780,Benomyl,72913,2-Aminobenzonitrile,photolysis,NA,NA,1655,28780,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 99",
3030,Dicamba,16125,"2,5-Dichloroanisole",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 160",
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",mammalian metabolism,Mammal,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7193221,PMID:7193221,
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",mammalian metabolism,Mammal,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"U.S. Dept. of Agriculture/Forest Service, Human Health and Ecological Risk Assessment for Dicamba (1918-00-9) SERA TR 04-43-17-06d, p.3-2 (November 24, 2004). Available from, as of June 15, 2017: http://www.fs.fed.us/foresthealth/pesticide/risk.shtml",
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",animal metabolism,Animal,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 522",
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Broadhurst et al  J Agr Food Chem 14 (6): 585-8 (1966),
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 160",
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA/Office of Pesticide Programs  Dicamba: Human Health Risk Assessment - Phase I p.5 (September 2005),
3030,Dicamba,3030,Dicamba,none,NA,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
3030,Dicamba,54340135,"2,5-Dichloro-3,6-dihydroxybenzoic acid",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 147",
3030,Dicamba,5784,"2,5-Dichlorobenzoic acid",plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 147",
3030,Dicamba,66,"2,5-Dichlorophenol",mammalian metabolism,Mammal,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7193221,PMID:7193221,
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Broadhurst et al  J Agr Food Chem 14 (6): 585-8 (1966),
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 564",
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 569",
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 160",
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 147",
3030,Dicamba,82075,5-Hydroxydicamba,plant metabolism,Plant,NA,311,3030,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA/Office of Pesticide Programs  Dicamba: Human Health Risk Assessment - Phase I p.5 (September 2005),
3120,Diuron,102319875,"1-(2-Hydroxy-3,4-dichlorophenyl)urea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,146035702,"N-(2-hydroxy-4,5-dichlorophenyl)-N'-methylurea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",human metabolism,Human,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",fungal metabolism,Fungi,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:17576805,PMID:17576805,
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-24",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",human metabolism,Human,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",fungal metabolism,Fungi,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",
3120,Diuron,3015415,"2-Amino-4,5-dichlorophenol",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,3120,Diuron,none,NA,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
3120,Diuron,54051871,"1-(6-Hydroxy-3,4-dichlorophenyl)urea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,54051871,"1-(6-Hydroxy-3,4-dichlorophenyl)urea",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,
3120,Diuron,7257,"3,4-Dichloroaniline",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,7257,"3,4-Dichloroaniline",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,
3120,Diuron,7257,"3,4-Dichloroaniline",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",
3120,Diuron,7257,"3,4-Dichloroaniline",human metabolism,Human,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",
3120,Diuron,7257,"3,4-Dichloroaniline",metabolism,NA,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Prevention, Pesticides and Toxic Substances; Reregistration Eligibility Decision Document for Diuron p.15 List A Case 0046 (September 2003). Available from, as of July 11, 2018: http://www.epa.gov/pesticides/reregistration/status.htm",
3120,Diuron,7258,"3,4-Dichlorophenol",mammalian metabolism,Mammal,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",
3120,Diuron,7443,"3,4-Dichloronitrobenzene",plant metabolism,Plant,NA,382,3120,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",
31645,Pirimicarb,135401759,"4(1H)-Pyrimidinone, 5,6-dimethyl-2-(methylamino)-",mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1170",
31645,Pirimicarb,135401759,"4(1H)-Pyrimidinone, 5,6-dimethyl-2-(methylamino)-",mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10414785,PMID:10414785,
31645,Pirimicarb,135402388,"2-Amino-5,6-dimethyl-1H-pyrimidin-4-one",mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1170",
31645,Pirimicarb,135402388,"2-Amino-5,6-dimethyl-1H-pyrimidin-4-one",mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10414785,PMID:10414785,
31645,Pirimicarb,135420611,"2-(Dimethylamino)-5,6-dimethyl-1H-pyrimidin-4-one",mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10414785,PMID:10414785,
31645,Pirimicarb,146037633,2-dimethylamino-6-hydroxymethyl-5-methyl-4-hydroxypyrimidine,mammalian metabolism,Mammal,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1170",
31645,Pirimicarb,31645,Pirimicarb,none,NA,NA,7005,31645,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
4169,Metolachlor,11831821,Metolachlor deschloro,mammalian metabolism,Mammal,NA,6706,4169,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA; Health Advisories for 50 Pesticides p.618 (1988) NTIS PB88-245931,
4169,Metolachlor,3017607,2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-hydroxy-1-methylethyl)acetamide,fungal metabolism,Fungi,NA,6706,4169,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 30",
4169,Metolachlor,3017607,2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-hydroxy-1-methylethyl)acetamide,fish metabolism,Fish,NA,6706,4169,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cruz SM et al; J Agric Food Chem 41 (4): 662-8 (1993),
4169,Metolachlor,4169,Metolachlor,none,NA,NA,6706,4169,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
4169,Metolachlor,670477,2-Chloro-N-(2-ethyl-6-methylphenyl)acetamide,fungal metabolism,Fungi,NA,6706,4169,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 30",
5216,Simazine,12584,Ammelide,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,12584,Ammelide,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 435",
5216,Simazine,12584,Ammelide,fungal metabolism,Fungi,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. 12 318 (1980)",
5216,Simazine,135408770,Ammeline,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135408770,Ammeline,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 435",
5216,Simazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",
5216,Simazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,13878,Deisopropylatrazine,mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED); Document ID: EPA-HQ-OPP-2005-0151-0023 p.16 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,13878,Deisopropylatrazine,animal metabolism,Animal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,13878,Deisopropylatrazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 539",
5216,Simazine,13878,Deisopropylatrazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,13878,Deisopropylatrazine,avian metabolism,Bird,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.17-18 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",mammalian metabolism,Mammal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED); Document ID: EPA-HQ-OPP-2005-0151-0023 p.16 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",animal metabolism,Animal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 539",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",avian metabolism,Bird,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.17-18 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135398734,Deisopropylhydroxyatrazine,animal metabolism,Animal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135398734,Deisopropylhydroxyatrazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135398734,Deisopropylhydroxyatrazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 435",
5216,Simazine,135408659,Hydroxysimazine,animal metabolism,Animal,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED), Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135408659,Hydroxysimazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 539",
5216,Simazine,135408659,Hydroxysimazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,135408659,Hydroxysimazine,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 435",
5216,Simazine,5216,Simazine,none,NA,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
5216,Simazine,7956,Cyanuric acid,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides and Toxic Substances; Simazine: Revised Preliminary HED Chapter of the Reregistration Eligibility Decision Document (RED) Document ID: EPA-HQ-OPP-2005-0151-0023 p.15 (May 31, 2005). Available from, as of June 6, 2007: http://www.regulations.gov/fdmspublic/component/main",
5216,Simazine,7956,Cyanuric acid,plant metabolism,Plant,NA,1765,5216,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 435",
6808,"1,2,3,6-Tetrahydrophthalimide",6808,"1,2,3,6-Tetrahydrophthalimide",none,NA,NA,5006,6808,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
8606,Captan,6808,"1,2,3,6-Tetrahydrophthalimide",mammalian metabolism,Mammal,NA,5006,6808,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"ENGST R, RAAB M; BROMATOTOXIC ASPECTS OF METABOLISM OF FUNGICIDAL PHTHALIMIDE DERIVATIVES; NAHRUNG 17(7) 731 (1973)",
8606,Captan,6808,"1,2,3,6-Tetrahydrophthalimide",mammalian metabolism,Mammal,NA,5006,6808,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,van Welie RTH et al,
8606,Captan,6808,"1,2,3,6-Tetrahydrophthalimide",human metabolism,Human,NA,5006,6808,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,van Welie RTH et al,
8606,Captan,6808,"1,2,3,6-Tetrahydrophthalimide",metabolism,NA,NA,5006,6808,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Kukla D et al,
7153,Mecoprop,14855,4-Chloro-2-methylphenol,plant metabolism,Plant,NA,1738,7153,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hartley, D. and H. Kidd (eds.). The Agrochemicals Handbook. Old Woking, Surrey, United Kingdom: Royal Society of Chemistry/Unwin Brothers Ltd., 1983., p. A255/oct 83",
7153,Mecoprop,185588,Mecoprop-P,plant metabolism,Plant,NA,1738,7153,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hartley, D. and H. Kidd (eds.). The Agrochemicals Handbook. Old Woking, Surrey, United Kingdom: Royal Society of Chemistry/Unwin Brothers Ltd., 1983., p. A255/oct 83",
7153,Mecoprop,7153,Mecoprop,none,NA,NA,1738,7153,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
7204,(4-Chloro-2-methylphenoxy)acetic acid,14855,4-Chloro-2-methylphenol,mammalian metabolism,Mammal,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 513",
7204,(4-Chloro-2-methylphenoxy)acetic acid,14855,4-Chloro-2-methylphenol,bacterial metabolism,Bacteria,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 116",
7204,(4-Chloro-2-methylphenoxy)acetic acid,22883,Cloxyfonac,plant metabolism,Plant,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. C-32",
7204,(4-Chloro-2-methylphenoxy)acetic acid,53993531,2-(4-Chloro-2-hydroxy-6-methylphenoxy)acetic acid,bacterial metabolism,Bacteria,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 116",
7204,(4-Chloro-2-methylphenoxy)acetic acid,54593777,2-(4-Chloro-5-hydroxy-2-methylphenoxy)acetic acid,bacterial metabolism,Bacteria,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 116",
7204,(4-Chloro-2-methylphenoxy)acetic acid,7204,(4-Chloro-2-methylphenoxy)acetic acid,none,NA,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
7204,(4-Chloro-2-methylphenoxy)acetic acid,79192,5-Chloro-2-methylphenol,bacterial metabolism,Bacteria,NA,1127,7204,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 116",
86102,Tebuconazole,86102,Tebuconazole,none,NA,NA,7448,86102,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,,
86102,Tebuconazole,9257,"1,2,4-Triazole",animal metabolism,Animal,NA,7448,86102,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues on Tebuconazole (107534-96-3). Available from, as of July 6, 2006: http://www.inchem.org/pages/jmpr.html",
86102,Tebuconazole,9257,"1,2,4-Triazole",metabolism,NA,NA,7448,86102,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"California Environmental Protection Agency/Department of Pesticide Regulation; Toxicology Data Review Summaries. Available from:  http://www.cdpr.ca.gov/docs/toxsums/toxsumlist.htm on Tebuconazole (107534-96-3) as of July 6, 2006.",
86102,Tebuconazole,9257,"1,2,4-Triazole",biotransformation,NA,NA,7448,86102,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues on Tebuconazole (107534-96-3). Available from, as of July 6, 2006: http://www.inchem.org/pages/jmpr.html",
13263,Ametryn,135398733,2-hydroxyametryn,Plant metabolism,Plant,NA,1710,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 17",
7220,"1,2,3-Benzotriazole",135399369,4-hydroxybenzotriazole,Mammalian metabolism,Mammal,NA,4143,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1178",
7220,"1,2,3-Benzotriazole",135420616,5-hydroxybenzotriazole,Mammalian metabolism,Mammal,NA,4143,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1178",
135398658,Folic acid,135444742,Tetrahydrofolic acid,Metabolism,NA,NA,2002,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Thomson.Micromedex. Drug Information for the  Health Care Professional. 24th ed. Volume 1.  Plus Updates. Content Reviewed by the United States Pharmacopeial Convention, Inc. Greenwood Village, CO. 2004., p. 1422",
135401907,Allopurinol,135398752,Oxypurinol,Metabolism,NA,NA,3004,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 3691",
135585372,C.I. Direct Brown 95,7111,Benzidine,Metabolism,Human,NA,5082,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 326 (1982)",
135585372,C.I. Direct Brown 95,18787,Monoacetylbenzidine,Metabolism,Human,NA,5082,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 326 (1982)",
135585372,C.I. Direct Brown 95,11942,Diacetylbenzidine,Metabolism,Human,NA,5082,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 326 (1982)",
135585372,C.I. Direct Brown 95,8411,ortho-Dianisidine,Metabolism,Human,NA,5082,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 326 (1982)",
135513128,C.I. Acid Orange 20,8479,Sulfanilic acid,Metabolism,Dog,NA,5493,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 176 (1975)",
135513128,C.I. Acid Orange 20,17815,4-Amino-1-naphthol,Metabolism,Dog,NA,5493,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 176 (1975)",
135398737,Clozapine,135409468,N-desmethylclozapine,Metabolism,NA,NA,6478,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bablenis E et al; Drug Intelligence and Clinical Pharmacy 23 (2): 109-15 (1989),
135398513,Acyclovir,135508007,9-carboxymethoxymethylguanine,Metabolism,NA,NA,6511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 769",
135398513,Acyclovir,135530051,8-hydroxy-9-(2-hydroxyethoxymethyl)guanine,Metabolism,NA,NA,6511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 769",
135398513,Acyclovir,135422933,Acyclovir monophosphate,Metabolism,NA,NA,6511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 769",
135398559,Leucovorin,135483998,5-Methyl tetrahydrofolate,Metabolism,NA,NA,6544,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"McEvoy, G.K. (ed.). American Hospital Formulary Service-  Drug Information 2005. Bethesda, MD: American Society of  Health-System Pharmacists, Inc. 2005 (Plus Supplements)., p. 3569",
135398739,Dideoxyinosine,135398638,Hypoxanthine,Metabolism,NA,NA,6548,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V76 158 (2000)",
135398739,Dideoxyinosine,1175,Uric acid,Metabolism,NA,NA,6548,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V76 158 (2000)",
135398739,Dideoxyinosine,1188,Xanthine,Metabolism,NA,NA,6548,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V76 158 (2000)",
135511839,Carbadox,9568819,Desoxycarbadox,Metabolism,Swine,NA,7028,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Food Additives; Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 27: Carbadox (1991). Available from, as of November 2, 2015: https://www.inchem.org/pages/jecfa.html",
135511839,Carbadox,96695,Quinoxaline-2-carboxylic acid,Metabolism,Swine,NA,7028,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Food Additives; Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 27: Carbadox (1991). Available from, as of November 2, 2015: https://www.inchem.org/pages/jecfa.html",
135491728,Clethodim,136068105,Clethodim sulfoxide,Metabolism,Rat,NA,7960,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues Evaluation for Clethodim (99129-21-2) (1994). Available from, as of June 17, 2011: https://www.inchem.org/pages/jmpr.html",
135398742,Valacyclovir,6287,L-valine,Metabolism,NA,NA,8084,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for VALTREX (valacyclovir hydrochloride) tablet, film coated (December 2011). Available from, as of November 25, 2012: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f8e0d8f8-cb73-4206-a484-88f5c4fbd719",
135398519,Valganciclovir,135398740,Ganciclovir,Metabolism,NA,NA,8085,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for VALCYTE (valganciclovir hydrochloride) tablet, film coated VALCYTE (valganciclovir hydrochloride) powder, for solution (Auguest 2010). Available from, as of November 25, 2012: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=dc548ff9-e8ea-4d6e-b9b4-e31f53ac4078",
3324,Famciclovir,135398748,Penciclovir,Metabolism,NA,NA,8123,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 815",
135398748,Penciclovir,135434855,Penciclovir triphosphate,Metabolism,NA,NA,8123,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 815",
128517,6-deoxy penciclovir,135398748,Penciclovir,Metabolism,NA,NA,8123,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 815",
135409642,Azilsartan medoxomil,135415867,Azilsartan,Metabolism,NA,NA,8208,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP), European Public Assessment Report (EPAR): Edarbi (Azilsartan Medoxomil) p.16 (2011). Available from, as of July 15, 2014: https://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/002293/WC500119206.pdf",
135406868,Nitrotriazolone,72916,Urazole,Metabolism,NA,NA,8399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"ECHA; Registration for 1,2-dihydro-5-nitro-3H-1,2,4-triazol-3-one (CAS 932-64-9); Available from, as of October 24, 2017: https://echa.europa.eu/registration-dossier/-/registered-dossier/5380",
135406868,Nitrotriazolone,946,Nitrite,Metabolism,NA,NA,8399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"ECHA; Registration for 1,2-dihydro-5-nitro-3H-1,2,4-triazol-3-one (CAS 932-64-9); Available from, as of October 24, 2017: https://echa.europa.eu/registration-dossier/-/registered-dossier/5380",
77797,Sulfluramid,69785,Perfluorooctanesulfonamide,Metabolism,Rat,NA,7100,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Arrendale RF et al; Journal of Agricultural and Food and Chemistry 37 (4): 1130-5 (1989),
8418,Anthracene,179115,"trans-1,2-dihydroxy-1,2-dihydroanthracene",Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Akhtar MN et al; J Chem Soc Perkin 1 (6): 1442-6 (1979),
8418,Anthracene,155464,"1,2-Dihydroxyanthracene",Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.40 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,11796,"2-Hydroxy-9,10-anthraquinone",Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.40 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,7018,Anthrone,Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.40 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,114831,Dihydrodiol,Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.40 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,69504,9-Formylanthracene,Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.42 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,13068,9-Methylanthracene,Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.42 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,114974,9-Hydroxymethyl-10-methylanthracene,Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.42 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,13076,"9,10-Dimethyl-anthracene",Metabolism,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.42 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",
8418,Anthracene,6780,"9,10-Anthraquinone",Metabolism,NA,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V32 112 (1983)",
13,"1,2,4-Trichlorobenzene",7271,"2,4,5-Trichlorophenol",Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2017752,PMID:2017752,
13,"1,2,4-Trichlorobenzene",13619,"2,3,5-Trichlorophenol",Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2017752,PMID:2017752,
13,"1,2,4-Trichlorobenzene",69103,Trichlorohydroquinone,Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2017752,PMID:2017752,
13,"1,2,4-Trichlorobenzene",13618,"2,3,6-Trichlorophenol",Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2017752,PMID:2017752,
13,"1,2,4-Trichlorobenzene",19597,"2,4,5-Trichlorothiophenol",Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3753195,PMID:3753195,
13,"1,2,4-Trichlorobenzene",32817,"3,4,6-Trichlorocatechol",Metabolism,NA,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3753195,PMID:3753195,
11487,"N,N-Diphenylamine",31208,4-Hydroxydiphenylamine,Metabolism,Human,NA,1108,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Sheftel, V.O.; Indirect Food Additives and Polymers. Migration and Toxicology. Lewis Publishers, Boca Raton, FL. 2000., p. 348",
6895,"1,2,3-Trichlorobenzene",27582,"2,3,4-Trichlorophenol",Metabolism,Rabbit,NA,1502,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-19",
6895,"1,2,3-Trichlorobenzene",11859,"3,4,5-Trichlorophenol",Metabolism,Rabbit,NA,1502,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-19",
6895,"1,2,3-Trichlorobenzene",32816,"3,4,5-Trichlorocatechol",Metabolism,Rabbit,NA,1502,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 773",
995,Phenanthrene,82105,4-Hydroxyphenanthrene,Metabolism,Rabbit,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",
995,Phenanthrene,10229,9-Hydroxyphenanthrene,Metabolism,Rabbit,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",
995,Phenanthrene,115062,"trans-1,2-dihydro-1,2-dihydroxyphenanthrene",Metabolism,Rabbit,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",
995,Phenanthrene,119398,"trans-3,4-dihydro-3,4-dihydroxyphenanthrene",Metabolism,Rabbit,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",
995,Phenanthrene,114831,Dihydrodiol,Metabolism,Rat,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V32 423 (1983)",
995,Phenanthrene,147284,"Phenanthrene 1,2-dihydrodiol",Metabolism,NA,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12878411,PMID:12878411,
6901,"Hexachloro-1,3-butadiene",3033729,"S-(1,2,3,4,4-pentachloro-1,3- butadienyl)-L-cysteine",Metabolism,NA,NA,2870,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2360207,PMID:2360207,
6901,"Hexachloro-1,3-butadiene",55395,Pentachloro-3-butenoic acid,Metabolism,NA,NA,2870,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6744254,PMID:6744254,
31423,Pyrene,16820,"1,8-Pyrene quinone",Metabolism,NA,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 357",
31423,Pyrene,151315,"trans-4,5-dihydro-4,5-dihydroxypyrene",Metabolism,Rabbit,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 44",
31423,Pyrene,165849,"1,6-Dihydroxypyrene",Metabolism,Rabbit,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 44",
31423,Pyrene,149604,"1,8-Dihydroxypyrene",Metabolism,Rabbit,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 44",
31423,Pyrene,21387,1-Hydroxypyrene,Metabolism,Rabbit,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 44",
31423,Pyrene,114831,Dihydrodiol,Metabolism,Rabbit,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V32 436 (1983)",
31423,Pyrene,15699,"1,6-Pyrenequinone",Metabolism,Rat,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7018664,PMID:7018664,
31423,Pyrene,160236,1-Methoxypyrene,Metabolism,NA,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Sack U et al; Appl and Environ Microbiol 63 (7): 2906-9 (1997),
31423,Pyrene,9543281,"4,5-Dihydroxypyrene",Metabolism,NA,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Searle, C. E. (ed.). Chemical Carcinogens. ACS Monograph 173. Washington, DC: American Chemical Society, 1976., p. 287",
9154,Fluoranthene,114831,Dihydrodiol,Metabolism,NA,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V32 359 (1983)",
9154,Fluoranthene,176953,3-Hydroxyfluoranthene,Metabolism,Tomato,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kolb M, Harms H; Environ Toxicol Chem 19 (5): 1304-10 (2000)",
9154,Fluoranthene,54934,"trans-2,3-dihydroxy-2,3-dihydrofluoranthene",Metabolism,NA,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2285310,PMID:2285310,
9154,Fluoranthene,148347,3-Fluoranthene-beta-glucopyranoside,Metabolism,NA,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2285310,PMID:2285310,
9154,Fluoranthene,55048,"2,3-Dihydro-2,3-dihydroxyfluoranthene",Metabolism,NA,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7127666,PMID:7127666,
37840,"1,2-Bis(2,4,6-tribromophenoxy)ethane",1483,Tribromophenol,Metabolism,Rat,NA,6099,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14659938,PMID:14659938,
6720,Pentachloronitrobenzene,8620,Pentachlorothiophenol,Metabolism,Fish,NA,6124,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bahig ME et al; Metabolism of pentachloronitrobenzene-(14)C (Quintozene) in fish;  Chemosphere 10 (3): 319 (1981),
62329,Musk xylene,101596489,"2-Amino-5-tert-butyl-1-methyl-3-hydroxymethyl-4,6-dinitrobenzene",Metabolism,Rat,NA,7692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Musk Xylene (81-15-2) p.58 (2005). Available from, as of June 15, 2017: https://echa.europa.eu/",
62329,Musk xylene,101597204,"4-Amino-5-tert-butyl-1-methyl-3-hydroxymethyl-2,6-dinitrobenzene",Metabolism,Rat,NA,7692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Musk Xylene (81-15-2) p.58 (2005). Available from, as of June 15, 2017: https://echa.europa.eu/",
13506,Amaranth,6790,Naphthionic acid,Metabolism,Rat,NA,569,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Food Safety Authority (EFSA); EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS): Scientific Opinion on the re-evaluation of Amaranth (E 123) as a food Additive. (June 2010). Available from, as of October 25, 2011: https://www.efsa.europa.eu/en/publications.htm",
13506,Amaranth,16177,"1-Amino-2-hydroxynaphthalene-3,6-disulfonic acid",Metabolism,Rat,NA,569,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. H-79",
6051,4-Aminoazobenzene,20085,4-Acetamidoazobenzene,Metabolism,Rat,NA,2137,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-31",
6051,4-Aminoazobenzene,403,4-Aminophenol,Metabolism,Rat,NA,2137,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-31",
6051,4-Aminoazobenzene,7814,para-Phenylenediamine,Metabolism,Rat,NA,2137,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-31",
6053,4-(Dimethylamino)azobenzene,6051,4-Aminoazobenzene,Metabolism,NA,NA,2692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gupta R, Dani HM; Toxicol Letters 45 (1): 49-54 (1989)",
6053,4-(Dimethylamino)azobenzene,107710,N-Hydroxy-4-aminoazobenzene,Metabolism,NA,NA,2692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gupta R, Dani HM; Toxicol Letters 45 (1): 49-54 (1989)",
10303,Methyl red,227,Anthranilic acid,Metabolism,NA,NA,2786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-39",
10303,Methyl red,7472,"N,N-Dimethyl-p-phenylenediamine",Metabolism,NA,NA,2786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-39",
19095,Ponceau 3R,8717,"2,4,5-Trimethylaniline",Metabolism,Rabbit,NA,2946,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 203 (1975)",
13297,Sudan I,403,4-Aminophenol,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,5801,2-Aminophenol,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,6115,Aniline,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,14535,1-Amino-2-naphthol,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,9718,Benzenediazonium,Metabolism,NA,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3378630,PMID:3378630,
17730,Sunset Yellow FCF,8479,Sulfanilic acid,Metabolism,Rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 262 (1975)",
17730,Sunset Yellow FCF,8483,N-Acetylsulfanilic acid,Metabolism,Rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 262 (1975)",
17730,Sunset Yellow FCF,145804,1-Amino-2-naphthol-6-sulfonic acid,Metabolism,Rabbit,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO Food Additive Series 549: Sunset Yellow FCF (1964). Available from, as of October 26, 2004: https://www.inchem.org/documents/jecfa/jecmono/v17je29.htm",
23673835,Methyl orange,7472,"N,N-Dimethyl-p-phenylenediamine",Metabolism,NA,NA,4322,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:370581,PMID:370581,
23673835,Methyl orange,8479,Sulfanilic acid,Metabolism,NA,NA,4322,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:370581,PMID:370581,
16015,Orange G,403,4-Aminophenol,Metabolism,Rabbit,NA,4348,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 184 (1975)",
16015,Orange G,5801,2-Aminophenol,Metabolism,Rabbit,NA,4348,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 184 (1975)",
16015,Orange G,6115,Aniline,Metabolism,Rabbit,NA,4348,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 184 (1975)",
135513128,Orange I,8479,Sulfanilic acid,Metabolism,Dog,NA,5493,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 176 (1975)",
135513128,Orange I,17815,4-Amino-1-naphthol,Metabolism,Dog,NA,5493,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 176 (1975)",
164825,Tartrazine,8479,Sulfanilic acid,Metabolism,NA,NA,7216,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Food Safety Authority (EFSA); Scientific Opinion of the ANS Panel on the re-evaluation Tartrazine (E 102) Published: 12 November 2009 Available from, as of June 28, 2011: https://www.efsa.europa.eu/en/publications.htm",
2272,Azobenzene,6115,Aniline,Metabolism,NA,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W. J., Jr. Toxicology of Pesticides Baltimore: Williams & Wilkins, 1975., p. 112",
2272,Azobenzene,7111,Benzidine,Metabolism,NA,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 78 (1974)",
2272,Azobenzene,31222,"1,2-Diphenylhydrazine",Metabolism,Rat,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Macholz R et al; Archives of Toxicology, Supplement 8: 373-6 (1985)",
8413,"3,3'-Dimethylbenzidine",19074,"3,3'-Dimethyl-N-acetylbenzidine",Metabolism,Rat,NA,1640,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"DHHS/NTP; Toxicology and Carcinogenesis Studies of 3,3'dimethylbenzidine dihydrochloride in F344/N Rats (Drinking Water Studies) p.14 (1991) Technical Rpt Series No. 390 NIH Pub No. 91-2845",
7340,o-Aminoazotoluene,7242,o-Toluidine,Metabolism,NA,NA,2639,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 67 (1975)",
7340,o-Aminoazotoluene,7252,"2,5-Diaminotoluene",Metabolism,NA,NA,2639,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 67 (1975)",
13816,C.I. Direct Red 2,8413,"3,3'-Dimethylbenzidine",Metabolism,Rat,NA,4226,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834799,PMID:6834799,
17059,Direct blue 15,8411,"3,3'-Dimethoxybenzidine",Metabolism,Rat,NA,4227,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7151244,PMID:7151244,
33258,Allura Red AC,145804,1-Amino-2-naphthol-6-sulfonic acid,Metabolism,NA,NA,7260,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additives Ser 15: Allura Red AC (1980). Available from, as of October 28, 2004: https://www.inchem.org/documents/jecfa/jecmono/v15je02.htm",
2272,Azobenzene,5801,2-Aminophenol,Metabolism,NA,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 209",
2272,Azobenzene,16897,2-(Phenylazo)phenol,Metabolism,NA,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 209",
2272,Azobenzene,15529,4-Hydroxyazobenzene,Metabolism,NA,NA,1513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 209",
8411,"3,3'-Dimethoxybenzidine",150059,N-Acetyl-o-dianisidine,N-acetylation,NA,NA,1627,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6137333,PMID:6137333,
8411,"3,3'-Dimethoxybenzidine",131862396,2-Amino-5-(4-amino-3-methoxyphenyl)phenol,O-demethylation,NA,NA,1627,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6137333,PMID:6137333,
8413,"3,3'-Dimethylbenzidine",626583,"N,N'-Diacetyl-3,3'-dimethylbenzidine",Metabolism,Rat,NA,1640,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"DHHS/NTP; Toxicology and Carcinogenesis Studies of 3,3'dimethylbenzidine dihydrochloride in F344/N Rats (Drinking Water Studies) p.14 (1991) Technical Rpt Series No. 390 NIH Pub No. 91-2845",
22960,CI Acid Red 114,8413,"3,3'-Dimethylbenzidine",Metabolism,Rodent,NA,1640,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2403837,PMID:2403837,
6053,4-(Dimethylamino)azobenzene,97486,4-Hydroxy-4'-dimethylaminoazobenzene,Metabolism,Rat,NA,2692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-81",
6053,4-(Dimethylamino)azobenzene,5743300,N-(p-(phenylazo)phenyl)acetohydroxamic acid,Metabolism,Rat,NA,2692,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 272",
6296,Trypan blue,19071,"3,6-Naphthalenedisulfonic acid, 1,7-diamino-8-hydroxy-",Metabolism,Rat,NA,2945,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 273 (1975)",
6296,Trypan blue,8413,"3,3'-Dimethylbenzidine",Metabolism,Rat,NA,2945,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834800,PMID:6834800,
19095,Ponceau 3R,16177,"4-Amino-3-hydroxy-2,7-naphthalenedisulfonic acid",Metabolism,NA,NA,2946,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 162",
19095,Ponceau 3R,7259,"2,5-Dimethylaniline",Metabolism,NA,NA,2946,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 162",
22830,Citrus red 2,167530377,"2,5-Dimethoxyphenylazo-2-naphthyl glucuronide",Metabolism,Rat,NA,2948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 105 (1975)",
22830,Citrus red 2,167530378,1-Amino-2-naphthol glucoronide,Metabolism,Rat,NA,2948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 105 (1975)",
22830,Citrus red 2,146011,1-Amino-2-naphthyl sulfate,Metabolism,Rat,NA,2948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 105 (1975)",
13297,Sudan I,4686811,4-Aminophenyl-beta-D-glucuronide,Metabolism,NA,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,4022661,p-Acetamidophenylglucuronide,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
13297,Sudan I,167530376,1-para-hydroxyphenylazo-2-naphthol glucuronide,Metabolism,Rabbit,NA,4132,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 228 (1975)",
17730,Sunset Yellow FCF,145804,1-Amino-2-naphthol-6-sulfonic acid,Metabolism,Rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 262 (1975)",
17730,Sunset Yellow FCF,16012,C.I. Acid orange 12,Metabolism,Sprague-Dawley rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11339284,PMID:11339284,
13816,C.I. Direct Red 2,19074,"3,3'-Dimethyl-N-acetylbenzidine",Metabolism,Rat,NA,4226,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834799,PMID:6834799,
13816,C.I. Direct Red 2,626583,"N,N'-Diacetyl-3,3'-dimethylbenzidine",Metabolism,Rat,NA,4226,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834799,PMID:6834799,
17059,Direct blue 15,54986,"N,N'-Diacetyldianisidine",Metabolism,Rat,NA,4227,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bowman MC et al; Proceedings of the third NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies p.426-36 (1984),
17059,Direct blue 15,150059,N-Acetyl-o-dianisidine,Metabolism,Rat,NA,4227,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bowman MC et al; Proceedings of the third NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies p.426-36 (1984),
7640,"Phenol, 4-[(4-aminophenyl)azo]-",153410,4'-Aminoazobenzen-4-yl-sulfate,Metabolism,NA,NA,5350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-41",
7640,"Phenol, 4-[(4-aminophenyl)azo]-",167530379,4'-Aminoazobenzen-4-yl-beta-D-glucuronide,Metabolism,NA,NA,5350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-41",
22961,CI Acid Red 114 (free acid form),8413,"3,3'-Dimethylbenzidine",Metabolism,Rodent,NA,1640,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2403837,PMID:2403837,
19096,Ponceau 3R free acid,16177,"4-Amino-3-hydroxy-2,7-naphthalenedisulfonic acid",Metabolism,NA,NA,2946,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 162",
19096,Ponceau 3R free acid,7259,"2,5-Dimethylaniline",Metabolism,NA,NA,2946,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 162",
6297,Trypan Blue free acid,19071,"3,6-Naphthalenedisulfonic acid, 1,7-diamino-8-hydroxy-",Metabolism,Rat,NA,2945,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 273 (1975)",
6297,Trypan Blue free acid,8413,"3,3'-Dimethylbenzidine",Metabolism,Rat,NA,2945,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834800,PMID:6834800,
17731,6-Hydroxy-5-((4-sulphophenyl)azo)naphthalene-2-sulphonic acid,145804,1-Amino-2-naphthol-6-sulfonic acid,Metabolism,Rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V8 262 (1975)",
17731,6-Hydroxy-5-((4-sulphophenyl)azo)naphthalene-2-sulphonic acid,16012,C.I. Acid orange 12,Metabolism,Sprague-Dawley rat,NA,4136,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11339284,PMID:11339284,
13817,Fast Scarlet,19074,"3,3'-Dimethyl-N-acetylbenzidine",Metabolism,Rat,NA,4226,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834799,PMID:6834799,
13817,Fast Scarlet,626583,"N,N'-Diacetyl-3,3'-dimethylbenzidine",Metabolism,Rat,NA,4226,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6834799,PMID:6834799,
17060,Pontamine sky blue 5B (acid form),54986,"N,N'-Diacetyldianisidine",Metabolism,Rat,NA,4227,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bowman MC et al; Proceedings of the third NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies p.426-36 (1984),
17060,Pontamine sky blue 5B (acid form),150059,N-Acetyl-o-dianisidine,Metabolism,Rat,NA,4227,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bowman MC et al; Proceedings of the third NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies p.426-36 (1984),
798,Indole,6097,3-Hydroxyindolin-2-one,Metabolism,Coccus,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. I-3",NA
798,Indole,444150,Indole-3-glycerol phosphate,Metabolism,"Neurospora, Eschericha",NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. I-3",NA
798,Indole,50591,1H-Indol-3-ol,Metabolism,Rat,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 45",NA
798,Indole,50591,1H-Indol-3-ol,Metabolism,NA,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 69",NA
6305,Tryptophan,798,Indole,Metabolism,Bacteria,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 155",NA
798,Indole,321710,Oxindole,Metabolism,Rat,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 45",NA
798,Indole,76955,5-Hydroxyoxindole,Metabolism,Rat,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 45",NA
798,Indole,7054,Isatin,Metabolism,Rat,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 45",NA
798,Indole,101399,2-(Formylamino)benzoic acid,Metabolism,NA,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 69",NA
798,Indole,227,Anthranilic acid,Metabolism,NA,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 69",NA
798,Indole,284,Formic Acid,Metabolism,NA,NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 69",NA
338,Salicylic Acid,10253,Salicyluric acid,Metabolism,Dog,NA,672,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Final Report of the Cosmetic Ingredient Review Expert Panel; Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MET-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate; p.29, (2003)",NA
338,Salicylic Acid,10253,Salicyluric acid,Metabolism,NA,NA,672,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IPCS; Poisons Information Monograph 642: Salicylic Acid (September 1998). Available from, as of February 13, 2008: https://www.inchem.org/documents/pims/pharm/pim642.htm#PartTitle:5.%20%20ROUTES%20OF%20ENTRY",NA
338,Salicylic Acid,3469,"2,5-Dihydroxybenzoic acid",Metabolism,Dog,NA,672,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Final Report of the Cosmetic Ingredient Review Expert Panel; Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MET-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate; p.29, (2003)",NA
2244,Aspirin,338,Salicylic Acid,Metabolism,Human,NA,672,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3680588,PMID:3680588,NA
338,Salicylic Acid,168876,"(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-hydroxybenzoyl)oxyoxane-2-carboxylic acid",Metabolism,Human,NA,672,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2219967,PMID:2219967,NA
243,Benzoic Acid,464,Hippuric Acid,Metabolism,Animal,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; IUCLID Dataset, Benzoic acid (65-85-0) (2000 CD-ROM edition). Available from, as of March 22, 2005: https://esis.jrc.ec.europa.eu/",NA
243,Benzoic Acid,464,Hippuric Acid,Metabolism,"man, monkeys, pig, rabbit, rodents, cat, dog, ferret & hedgehog",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 407",NA
243,Benzoic Acid,115145,Benzoyl glucuronide,Metabolism,NA,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cosmetic Ingredient Review Expert Panel; International Journal of Toxicology 20 (suppl. 3): 23-50 (2001),NA
243,Benzoic Acid,115145,Benzoyl glucuronide,Metabolism,Dog,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety's Concise International Chemical Assessment  Documents. Number 26: Benzoic acid and Sodium Benzoate (2000). Available from, as of March 24, 2005: https://www.inchem.org/pages/cicads.html",NA
243,Benzoic Acid,439689,Benzoylagmatine,Metabolism,"scorpion, peripatus",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",NA
243,Benzoic Acid,273355,5-{[Amino(imino)methyl]amino}-2-(benzoylamino)pentanoic acid,Metabolism,"scorpion peripatus; boophilus, eperia, tegenaria, mitopus, and Phalangium",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",NA
243,Benzoic Acid,240,Benzaldehyde,Metabolism,"spergillus neurospora, and polystictus",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",NA
243,Benzoic Acid,100001,N-Benzoylhistidine,Metabolism,peripatus,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-7",NA
243,Benzoic Acid,7420,3-Hydroxybenzoic acid,Metabolism,rabbit,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-8",NA
243,Benzoic Acid,135,4-Hydroxybenzoic acid,Metabolism,"Aspergillus, plants, Polyporus, Trichoderma, yeast",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-8",NA
243,Benzoic Acid,184849,"N(2),N(5)-dibenzoyl-L-ornithine",Metabolism,"anseriformes, galliformes",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"LaDu, B.N., H.G. Mandel, and E.L. Way. Fundamentals of Drug Metabolism and Disposition. Baltimore: Williams and Wilkins, 1971., p. 195",NA
980,4-Nitrophenol,403,4-Aminophenol,Metabolism,rat hepatocytes,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2876857,PMID:2876857,NA
980,4-Nitrophenol,80349,4-Nitrophenyl sulfate,Metabolism,rabbit,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. N-18",NA
980,4-Nitrophenol,80349,4-Nitrophenyl sulfate,Metabolism,Rat,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3606659,PMID:3606659,NA
980,4-Nitrophenol,3505109,4-Nitrocatechol,Metabolism,Rabbit,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. N-18",NA
980,4-Nitrophenol,3505109,4-Nitrocatechol,Metabolism,Rabbit,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Robinson D et al; Biochemical Journal 50: 221-7 (1951),NA
7485,4-Nitroanisole,980,4-Nitrophenol,Metabolism,rat hepatocytes,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2876857,PMID:2876857,NA
991,Parathion,980,4-Nitrophenol,Metabolism,Mice,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3948636,PMID:3948636,NA
9395,Paraoxon,980,4-Nitrophenol,Metabolism,Mice,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3948636,PMID:3948636,NA
7416,Nitrobenzene,980,4-Nitrophenol,Metabolism,male Fischer-344-rats,NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6836574,PMID:6836574,NA
949,"N,N-Dimethylaniline",950,"N,N-Dimethylaniline N-oxide",Metabolism,guinea pig,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
949,"N,N-Dimethylaniline",950,"N,N-Dimethylaniline N-oxide",Metabolism,rat and pig,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-87",NA
949,"N,N-Dimethylaniline",950,"N,N-Dimethylaniline N-oxide",Metabolism,red-winged blackbirds and albino rats,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1207400,PMID:1207400,NA
949,"N,N-Dimethylaniline",7515,N-Methylaniline,Metabolism,fortified guinea pig hepatic microsomal preparations ,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
949,"N,N-Dimethylaniline",7515,N-Methylaniline,Metabolism,dogs,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"KIESE M, RENNER G; NAUNYN-SCHMIEDEBERG'S ARCH PHARMACOL 283 (2): 143 (1974)",NA
949,"N,N-Dimethylaniline",6115,Aniline,Metabolism,fortified guinea pig hepatic microsomal preparations,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
949,"N,N-Dimethylaniline",459235,2-(Dimethylamino)phenol,Metabolism,fortified guinea pig hepatic microsomal preparations,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
949,"N,N-Dimethylaniline",5931,4-(Methylamino)phenol,Metabolism,dogs,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"KIESE M, RENNER G; NAUNYN-SCHMIEDEBERG'S ARCH PHARMACOL 283 (2): 143 (1974)",NA
949,"N,N-Dimethylaniline",403,4-Aminophenol,Metabolism,fortified guinea pig hepatic microsomal preparations ,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
949,"N,N-Dimethylaniline",403,4-Aminophenol,Metabolism,dog,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"KIESE M, RENNER G; NAUNYN-SCHMIEDEBERG'S ARCH PHARMACOL 283 (2): 143 (1974)",NA
949,"N,N-Dimethylaniline",22174,4-(Dimethylamino)phenol,Metabolism,dog,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"KIESE M, RENNER G; NAUNYN-SCHMIEDEBERG'S ARCH PHARMACOL 283 (2): 143 (1974)",NA
949,"N,N-Dimethylaniline",5801,2-Aminophenol,Metabolism,dog,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"KIESE M, RENNER G; NAUNYN-SCHMIEDEBERG'S ARCH PHARMACOL 283 (2): 143 (1974)",NA
949,"N,N-Dimethylaniline",712,Formaldehyde,Metabolism,Hepatic microsomes prepared from red-winged blackbirds and albino rats,NA,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1207400,PMID:1207400,NA
938,Nicotinic acid,936,Nicotinamide,Metabolism,male Sprague-Dawley rats,NA,1237,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin p.8; Intl J of Toxicology 24 (Suppl 5): 1-31 (2005). Available from, as of June 4, 2018: https://www.cir-safety.org/ingredients",NA
936,Nicotinamide,68499,Nicotinuric acid,Metabolism,Human,NA,1237,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:135660,PMID:135660,NA
936,Nicotinamide,440810,"1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide",Metabolism,Human,NA,1237,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin p.6; Intl J of Toxicology 24 (Suppl 5): 1-31 (2005). Available from, as of June 4, 2018: https://www.cir-safety.org/ingredients",NA
936,Nicotinamide,72925,6-Hydroxynicotinamide,Metabolism,Rat,NA,1237,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin p.8; Intl J of Toxicology 24 (Suppl 5): 1-31 (2005). Available from, as of June 4, 2018: https://www.cir-safety.org/ingredients",NA
936,Nicotinamide,72924,6-Hydroxynicotinic acid,Metabolism,Rat,NA,1237,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin p.8; Intl J of Toxicology 24 (Suppl 5): 1-31 (2005). Available from, as of June 4, 2018: https://www.cir-safety.org/ingredients",NA
323,Coumarin,5281426,Umbelliferone,Metabolism,Mouse,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Born SL, et al; Food Chem Toxicol 41(2): p 247-58 (2003)",NA
323,Coumarin,5281426,Umbelliferone,Metabolism,Human,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",NA
323,Coumarin,5281426,Umbelliferone,Metabolism,Human,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1306122,PMID:1306122,NA
323,Coumarin,5281426,Umbelliferone,Metabolism,"rat, mouse, hamster, rabbit, guinea pig, cat, dog, cynomolgus monkey and human",NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1381906,PMID:1381906,NA
323,Coumarin,5281426,Umbelliferone,Metabolism,human,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1409832,PMID:1409832,NA
323,Coumarin,11970,2-Hydroxyphenylacetic acid,Metabolism,F344 rats,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Born SL, et al; Food Chem Toxicol 41(2): p 247-58 (2003)",NA
323,Coumarin,11970,2-Hydroxyphenylacetic acid,Metabolism,NA,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",NA
323,Coumarin,126771,"1a,7b-Dihydrooxireno[2,3-c]chromen-2-one",Metabolism,Rat,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Fentem JH, Fry JR; Comp Biochem Physiol C 104 (1) 1-8 (1993)",intermediate
323,Coumarin,126771,"1a,7b-Dihydrooxireno[2,3-c]chromen-2-one",Metabolism,NA,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",intermediate
323,Coumarin,160897,2-Hydroxyphenylacetaldehyde,Metabolism,"rat, gerbil and human liver microsomes",NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1496825,PMID:1496825,NA
323,Coumarin,160897,2-Hydroxyphenylacetaldehyde,Metabolism,rat hepatic microsomes,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1555800,PMID:1555800,NA
323,Coumarin,280,Carbon Dioxide,Metabolism,NA,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",NA
323,Coumarin,122783,8-Hydroxycoumarin,Metabolism,NA,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",NA
323,Coumarin,5281416,Esculetin,Metabolism,NA,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 202 (2000)",NA
323,Coumarin,13650,3-Hydroxycoumarin,Metabolism,rant and human liver microsomes,CYP3A and CYP1A ,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1496825,PMID:1496825,NA
2160,Amitriptyline,4543,Nortriptyline,Metabolism,NA,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2015; Drug Information 2015. Bethesda, MD. 2015, p. 2399",NA
2160,Amitriptyline,4543,Nortriptyline,Metabolism,Human,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kraak JC, Bijster P; J Chromatogr Biomed 143 (Sep 1): 499-512 (1977)",NA
2160,Amitriptyline,4543,Nortriptyline,Metabolism,human liver microsomes,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7473143,PMID:7473143,NA
2160,Amitriptyline,160755,Desmethylnortriptyline,Metabolism,human,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kraak JC, Bijster P; J Chromatogr Biomed 143 (Sep 1): 499-512 (1977)",NA
2160,Amitriptyline,155720,10-Hydroxyamitriptyline,Metabolism,human,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kraak JC, Bijster P; J Chromatogr Biomed 143 (Sep 1): 499-512 (1977)",NA
2160,Amitriptyline,6420504,10-Hydroxynortriptyline,Metabolism,human,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kraak JC, Bijster P; J Chromatogr Biomed 143 (Sep 1): 499-512 (1977)",NA
20313,Amitriptylinoxide,2160,Amitriptyline,Metabolism,NA,NA,3007,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1859509,PMID:1859509,NA
2519,Caffeine,69726,1-Methyluric acid,Metabolism,NA,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569",NA
2519,Caffeine,69726,1-Methyluric acid,Metabolism,Human,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,80220,1-Methylxanthine,Metabolism,NA,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569",NA
2519,Caffeine,80220,1-Methylxanthine,Metabolism,Human,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,68374,7-Methylxanthine,Metabolism,NA,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569",NA
2519,Caffeine,2153,Theophylline,Metabolism,preterm neonates,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569",NA
2153,Theophylline,2519,Caffeine,Metabolism,preterm neonates,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 2569",NA
2519,Caffeine,2153,Theophylline,Metabolism,monkey,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V51 322 (1991)",NA
2519,Caffeine,2153,Theophylline,Metabolism,Rats and mice,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,108214,5-Acetylamino-6-formylamino-3-methyluracil,Metabolism,Human,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V51 322 (1991)",NA
2519,Caffeine,108214,5-Acetylamino-6-formylamino-3-methyluracil,Metabolism,Human,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,5429,Theobromine,Metabolism,Human and Rat,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V51 322 (1991)",NA
2519,Caffeine,5429,Theobromine,Metabolism,Rat and mouse,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,91611,"1,7-Dimethyluric acid",Metabolism,Human,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,70122,"1,3-Dimethyluracil",Metabolism,Rat and mouse,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
2519,Caffeine,89514338,Trimethyluric acid,Metabolism,Rat and mouse,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
3030,Dicamba,82075,5-Hydroxydicamba,Metabolism,wheat and bluegrass plant,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Broadhurst et al; J Agr Food Chem 14 (6): 585-8 (1966),NA
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",Metabolism,wheat and bluegrass,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Broadhurst et al; J Agr Food Chem 14 (6): 585-8 (1966),NA
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",Metabolism,barley and wheat,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 160",NA
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",Metabolism,lactating cows,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7193221,PMID:7193221,NA
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",Metabolism,"rats, mice, rabbits, and dogs",NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"U.S. Dept. of Agriculture/Forest Service, Human Health and Ecological Risk Assessment for Dicamba (1918-00-9) SERA TR 04-43-17-06d, p.3-2 (November 24, 2004). Available from, as of June 15, 2017: https://www.fs.fed.us/foresthealth/pesticide/risk.shtml",NA
3030,Dicamba,18844,"3,6-Dichloro-2-hydroxybenzoic acid",Metabolism,Plant,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA/Office of Pesticide Programs; Dicamba: Human Health Risk Assessment - Phase I p.5 (September 2005),NA
3030,Dicamba,54340135,"2,5-Dichloro-3,6-dihydroxybenzoic acid",Metabolism,barley plants,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 147",NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,Cotton,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-24",NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,Cunninghamella echinulata,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,corn seedlings,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,Human,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",NA
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",Metabolism,corn seedlings,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",NA
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",Metabolism,Rat,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,NA
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",Metabolism,Human,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",NA
3120,Diuron,7257,"3,4-Dichloroaniline",Metabolism,rat,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,NA
3120,Diuron,7257,"3,4-Dichloroaniline",Metabolism,Human,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 312",NA
3120,Diuron,7257,"3,4-Dichloroaniline",Metabolism,NA,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Prevention, Pesticides and Toxic Substances; Reregistration Eligibility Decision Document for Diuron p.15 List A Case 0046 (September 2003). Available from, as of July 11, 2018: https://www.epa.gov/pesticides/reregistration/status.htm",NA
3120,Diuron,3015415,"2-Amino-4,5-dichlorophenol",Metabolism,albino rats,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",NA
3120,Diuron,7258,"3,4-Dichlorophenol",Metabolism,dogs,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",NA
3120,Diuron,7443,"3,4-Dichloronitrobenzene",Metabolism,corn seedlings,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 338",NA
3821,Ketamine,123767,Norketamine,Metabolism,NA,NA,2180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Brunton, L. Chabner, B, Knollman, B. Goodman and Gillman's The Pharmaceutical Basis of Therapeutics, Twelth Edition, McGraw Hill Medical, New York, NY. 2011, p. 539",NA
3821,Ketamine,123767,Norketamine,Metabolism,NA,cytochrome p450 (CYP3A4),2180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1109",NA
3821,Ketamine,123767,Norketamine,Metabolism,dogs,NA,2180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1911019,PMID:1911019,NA
3821,Ketamine,123767,Norketamine,Metabolism,human,NA,2180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:22516044,PMID:22516044,NA
3821,Ketamine,123767,Norketamine,Metabolism,NA,NA,2180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:23183107,PMID:23183107,NA
4114,Methoxsalen,65090,Xanthotoxol,Metabolism,NA,NA,2505,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists; Drug Information 2018. Bethesda, MD. 2018",NA
4114,Methoxsalen,65090,Xanthotoxol,Metabolism,Rat,NA,2505,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,NOZU T ET AL; OYO YAKURI 18 (3): 497 (1979),NA
4114,Methoxsalen,5385192,5-Hydroxyxanthotoxin,Metabolism,Rat,NA,2505,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,NOZU T ET AL; OYO YAKURI 18 (3): 497 (1979),NA
4114,Methoxsalen,5376215,"7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dihydroxy-",Metabolism,Rat,NA,2505,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,NOZU T ET AL; OYO YAKURI 18 (3): 497 (1979),NA
2554,Carbamazepine,114709,Licarbazepine,Metabolism,NA,NA,3019,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7614907,PMID:7614907,NA
2554,Carbamazepine,2555,"Carbamazepine-10,11-epoxide",Metabolism,rat,NA,3019,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7891336,PMID:7891336,NA
3100,Diphenhydramine,597513,(Benzhydryloxy)acetic acid,Metabolism,NA,NA,3066,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 11",NA
3100,Diphenhydramine,40791,2-(Diphenylmethoxy)-N-methylethylamine,Metabolism,Cunninghamella elegans,NA,3066,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10772471,PMID:10772471,NA
3672,Ibuprofen,10444113,Carboxyibuprofen,Metabolism,Human,NA,3099,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. I-14",NA
3676,Lidocaine,24415,Monoethylglycinexylidide,Metabolism,NA,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697",NA
3676,Lidocaine,24415,Monoethylglycinexylidide,Metabolism,NA,CYPs,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Brunton, L. Chabner, B, Knollman, B. Goodman and Gillman's The Pharmaceutical Basis of Therapeutics, Twelth Edition, McGraw Hill Medical, New York, NY. 2011, p. 573",NA
3676,Lidocaine,24415,Monoethylglycinexylidide,Metabolism,Human,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11321382,PMID:11321382,NA
3676,Lidocaine,24415,Monoethylglycinexylidide,Metabolism,Horse,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18267881,PMID:18267881,NA
3676,Lidocaine,24415,Monoethylglycinexylidide,Metabolism,Human,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:21131461,PMID:21131461,NA
3676,Lidocaine,87833,Glycinexylidide,Metabolism,NA,CYPs,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Brunton, L. Chabner, B, Knollman, B. Goodman and Gillman's The Pharmaceutical Basis of Therapeutics, Twelth Edition, McGraw Hill Medical, New York, NY. 2011, p. 573",NA
3676,Lidocaine,87833,Glycinexylidide,Metabolism,Horse,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18267881,PMID:18267881,NA
3676,Lidocaine,76543,"4-Amino-3,5-dimethylphenol",Metabolism,NA,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697",NA
3676,Lidocaine,76543,"4-Amino-3,5-dimethylphenol",Metabolism,NA,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Brunton, L. Chabner, B, Knollman, B. Goodman and Gillman's The Pharmaceutical Basis of Therapeutics, Twelth Edition, McGraw Hill Medical, New York, NY. 2011, p. 573",NA
3676,Lidocaine,76543,"4-Amino-3,5-dimethylphenol",Metabolism,human,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:408479,PMID:408479,NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,human,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:408479,PMID:408479,NA
4937,Propazine,22563,Deethylatrazine,Metabolism,Animal,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",NA
4937,Propazine,18831,"6-Chloro-1,3,5-triazine-2,4-diamine",Metabolism,Animal,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bradway DE, Moseman RF; J Agric Food Chem 30 (2): 244-7 (1982)",NA
4937,Propazine,135461611,"1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)-",Metabolism,Setaria and Panicum,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 281",NA
4937,Propazine,135461611,"1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)-",Metabolism,plant,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin, C.D.S. (ed.). The Pesticide Manual - World Compendium. 10th ed. Surrey, UK: The British Crop Protection Council, 1994., p. 852",NA
4937,Propazine,135461611,"1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)-",Metabolism,plant,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides Programs; Propazine: Revised HED Risk Assessment for the Tolerance Reassessment Eligibility Decision Document (TRED) which includes a New Use on Grain Sorghum, Document ID: EPA-HQ-OPP-2005-0496-0004 p.10 (December 2005). Available from, as of June 11, 2007: https://www.regulations.gov",NA
4937,Propazine,135461611,"1,3,5-Triazin-2(1H)-one, 4,6-bis((1-methylethyl)amino)-",Metabolism,plant,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Weed Science Society of America. Herbicide Handbook. 5th ed. Champaign, Illinois: Weed Science Society of America, 1983., p. 411",NA
4937,Propazine,280,Carbon Dioxide,Metabolism,lactating goats,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 317",NA
4937,Propazine,13878,Deisopropylatrazine,Metabolism,Rat,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides Programs; Propazine: Revised HED Risk Assessment for the Tolerance Reassessment Eligibility Decision Document (TRED) which includes a New Use on Grain Sorghum, Document ID: EPA-HQ-OPP-2005-0496-0004 p.10 (December 2005). Available from, as of June 11, 2007: https://www.regulations.gov",NA
4937,Propazine,7956,Cyanuric acid,Metabolism,Rat and plant,NA,1400,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticides Programs; Propazine: Revised HED Risk Assessment for the Tolerance Reassessment Eligibility Decision Document (TRED) which includes a New Use on Grain Sorghum, Document ID: EPA-HQ-OPP-2005-0496-0004 p.10 (December 2005). Available from, as of June 11, 2007: https://www.regulations.gov",NA
4284,Diethyltoluamide,93103,"Benzamide, N-ethyl-3-methyl-",Metabolism,Human,NA,1582,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24645428,PMID:24645428,NA
5430,Thiabendazole,108227,5-Hydroxythiabendazole,Metabolism,NA,NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 65",NA
5430,Thiabendazole,108227,5-Hydroxythiabendazole,Metabolism,"mice, rats and humans",NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicine Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines Evaluation Unit, Committee for Veterinary Medicinal Products; Thiabendazole (148-79-8) EMEA/MRL/868/03, Summary Report (June 2004). Available from, as of June 10, 2009: https://www.ema.europa.eu/pdfs/vet/mrls/086803en.pdf",NA
5430,Thiabendazole,108227,5-Hydroxythiabendazole,Metabolism,NA,NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 970",NA
5430,Thiabendazole,10402363,"1H-Benzamidazol-5-ol, 2-(4-thiazolyl)-, hydrogen sulfate (ester)",Metabolism,"mice, rats and humans",NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicine Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines Evaluation Unit, Committee for Veterinary Medicinal Products; Thiabendazole (148-79-8) EMEA/MRL/868/03, Summary Report (June 2004). Available from, as of June 10, 2009: https://www.ema.europa.eu/pdfs/vet/mrls/086803en.pdf",NA
5430,Thiabendazole,70322,2-Acetylbenzimidazole,Metabolism,rat,NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicine Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines Evaluation Unit, Committee for Veterinary Medicinal Products; Thiabendazole (148-79-8) EMEA/MRL/868/03, Summary Report (June 2004). Available from, as of June 10, 2009: https://www.ema.europa.eu/pdfs/vet/mrls/086803en.pdf",NA
5430,Thiabendazole,445686,1H-Benzo[d]imidazole-2-carboxamide,Metabolism,beet leaves,NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 259",During sunlight exposure
5430,Thiabendazole,5798,Benzimidazole,Metabolism,beet leaves,NA,2027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides, Update II. U.S. Department of the Interior, Fish Wildlife Service, Special Scientific Report - Wildlife No. 2l2. Washington, DC: U.S. Government Printing Office, 1978., p. 259",During sunlight exposure
5798,Benzimidazole,72913,2-Aminobenzonitrile,Metabolism,melon plants,NA,2797,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,ROUCHAUD JP ET AL; PESTIC SCI 8(1) 31-4 (1977),NA
5798,Benzimidazole,7243,o-PHENYLENEDIAMINE,Metabolism,melon plants,NA,2797,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,ROUCHAUD JP ET AL; PESTIC SCI 8(1) 31-4 (1977),NA
5798,Benzimidazole,3082533,5-Hydroxybenzimidazole,Metabolism,rat,NA,2797,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,TYLER TR ET AL; DRUG METAB DISPOS 4(2) 177-9 (1976),NA
4173,Metronidazole,12760,2-Methyl-5-nitroimidazole,Metabolism,NA,NA,3129,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V13 118 (1977)",NA
3016,Diazepam,4616,Oxazepam,Metabolism,NA,NA,3140,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10022206,PMID:10022206,NA
2809,Clorazepate,4616,Oxazepam,Metabolism,Mice,NA,3140,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2908106,PMID:2908106,NA
5865,Prednisone,5755,Prednisolone,Metabolism,"by liver, lung and renal tissue",NA,3168,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V26 300 (1981)",NA
5755,Prednisolone,5865,Prednisone,Metabolism,"by liver, lung and renal tissue",NA,3168,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V26 300 (1981)",NA
5865,Prednisone,5755,Prednisolone,Metabolism,NA,NA,3168,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V26 303 (1981)",NA
5329,Sulfamethoxazole,114821,Sulfamethoxazole hydroxylamine,Metabolism,human liver microsome,NA,3186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V79 366",NA
5329,Sulfamethoxazole,114821,Sulfamethoxazole hydroxylamine,Metabolism,human,NA,3186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8062495,PMID:8062495,NA
5329,Sulfamethoxazole,114821,Sulfamethoxazole hydroxylamine,Metabolism,NA,NA,3186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8839055,PMID:8839055,NA
5329,Sulfamethoxazole,65280,Acetylsulfamethoxazole,Metabolism,Human,NA,3186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V79 366",NA
5754,Hydrocortisone,5864,Tetrahydrocortisol,Metabolism,alloxan diabetic rats,NA,3339,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3259502,PMID:3259502,NA
5754,Hydrocortisone,222786,Cortisone,Metabolism,Rat,NA,3339,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3259502,PMID:3259502,NA
6115,Aniline,7518,N-Phenylhydroxylamine,Metabolism,pig,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-56",NA
6115,Aniline,7518,N-Phenylhydroxylamine,Metabolism,NA,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 224",NA
6115,Aniline,7518,N-Phenylhydroxylamine,Metabolism,Japanese quail,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Blaauboer BJ, Wit JG; Biol Oxid Nitrogen, Proc Int Symp 2nd: 369-74 (1978)",NA
6115,Aniline,403,4-Aminophenol,Metabolism,Japanese quail,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Blaauboer BJ, Wit JG; Biol Oxid Nitrogen, Proc Int Symp 2nd: 369-74 (1978)",NA
6115,Aniline,403,4-Aminophenol,Metabolism,NA,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 224",NA
6115,Aniline,403,4-Aminophenol,Metabolism,rat,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 183",NA
6115,Aniline,69331,4-Aminobenzyl alcohol,Metabolism,bacteria,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-56",NA
6115,Aniline,14323,"Butanamide, N-phenyl-",Metabolism,pig,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-56",NA
6115,Aniline,7515,N-Methylaniline,Metabolism,rabbit,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-56",NA
6115,Aniline,431079,Phenylsulfamic acid,Metabolism,NA,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 32 (1974)",NA
6115,Aniline,11568,3-Aminophenol,Metabolism,dogs and rabbits,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 32 (1974)",NA
6115,Aniline,11972,2-Acetamidophenol,Metabolism,rabbit,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 32 (1974)",NA
6115,Aniline,904,Acetanilide,Metabolism,rabbit,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 32 (1974)",NA
6115,Aniline,904,Acetanilide,Metabolism,human,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10876991,PMID:10876991,NA
6115,Aniline,904,Acetanilide,Metabolism,human,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:26233686,PMID:26233686,NA
6115,Aniline,280,Carbon Dioxide,Metabolism,rabbit,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 32 (1974)",NA
6115,Aniline,1983,Acetaminophen,Metabolism,human,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10876991,PMID:10876991,NA
6115,Aniline,1983,Acetaminophen,Metabolism,human,NA,43,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:26233686,PMID:26233686,NA
7047,Quinoline,135697998,"Quinoline-5,6-diol",Metabolism,rabbit,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. Q-5",NA
7047,Quinoline,135697998,"Quinoline-5,6-diol",Metabolism,human,CYP2A6,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8824525,PMID:8824525,NA
7047,Quinoline,11376,3-Hydroxyquinoline,Metabolism,rabbit,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. Q-5",NA
7047,Quinoline,11376,3-Hydroxyquinoline,Metabolism,human and rat,CYP2E1,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8824525,PMID:8824525,NA
7047,Quinoline,11376,3-Hydroxyquinoline,Metabolism,NA,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 285",Acid/base treatment
7047,Quinoline,6038,2-Hydroxyquinoline,Metabolism,rabbit,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. Q-5",NA
7047,Quinoline,6038,2-Hydroxyquinoline,Metabolism,NA,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 44",NA
7047,Quinoline,6038,2-Hydroxyquinoline,Metabolism,Bacteria,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2514722,PMID:2514722,Intermediate
7047,Quinoline,1923,8-Hydroxyquinoline,Metabolism,NA,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 44",NA
7047,Quinoline,177065,"2,6-Dihydroxyquinoline",Metabolism,NA,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 44",NA
7047,Quinoline,177065,"2,6-Dihydroxyquinoline",Metabolism,Bacteria,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2514722,PMID:2514722,NA
7047,Quinoline,122783,8-Hydroxycoumarin,Metabolism,Bacteria,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2514722,PMID:2514722,NA
7047,Quinoline,15366,Quinoline 1-oxide,Metabolism,rat liver homogenate,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6883639,PMID:6883639,NA
7047,Quinoline,15366,Quinoline 1-oxide,Metabolism,rat liver microsomes,NA,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7160026,PMID:7160026,NA
7047,Quinoline,15366,Quinoline 1-oxide,Metabolism,human liver microsomes,CYP2A6,121,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8824525,PMID:8824525,NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,Rat liver and human liver and dog,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/ATSDR; Toxicological Profile for Benzidine p. 58 (2001),NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,pigeon,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-5",NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,"rat, hamster, guinea pig",NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 167 (1982)",NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,human and rat bladder organ cultures,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6733857,PMID:6733857,NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,dog,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7548754,PMID:7548754,NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,human,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Sciarini LJ, Meigs JW; Arch Environ Health 2: 423-8 (1961) as cited in USEPA; Health Effects Review: Benzidine and Benzidine-Based Dyes p.7 (1980) EPA 68-01-586",NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,rat,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,TANAKA K ET AL; INT ARCH OCCUP ENVIRON HEALTH 49 (2): 177-85 (1981),NA
7111,Benzidine,18787,N-Acetylbenzidine,Metabolism,human,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Zenser TV et al; Drug Metab Dispos 1998 26 (9): 856-9 (1998),NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,"human, rat and dog",NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/ATSDR; Toxicological Profile for Benzidine p. 58 (2001),NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,rac cytosol,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 167 (1982)",NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,human and rat bladder organ cultures,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6733857,PMID:6733857,NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,dog,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7548754,PMID:7548754,NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,human,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Sciarini LJ, Meigs JW; Arch Environ Health 2: 423-8 (1961) as cited in USEPA; Health Effects Review: Benzidine and Benzidine-Based Dyes p.7 (1980) EPA 68-01-586",NA
7111,Benzidine,11942,"N,N'-Diacetylbenzidine",Metabolism,rat,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,TANAKA K ET AL; INT ARCH OCCUP ENVIRON HEALTH 49 (2): 177-85 (1981),NA
7111,Benzidine,22483774,3-Hydroxybenzidine,Metabolism,beta-naphthoflavone-treated rats,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/ATSDR; Toxicological Profile for Benzidine p. 59 (2001),NA
7111,Benzidine,22483774,3-Hydroxybenzidine,Metabolism,dog,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-5",NA
7111,Benzidine,22483774,3-Hydroxybenzidine,Metabolism,NA,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V1 83 (1972)",NA
7111,Benzidine,22483774,3-Hydroxybenzidine,Metabolism,dog,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2403856,PMID:2403856,NA
7111,Benzidine,13140840,n-Hydroxy-n-acetylbenzidine,Metabolism,NA,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/ATSDR; Toxicological Profile for Benzidine p. 60 (2001),NA
7111,Benzidine,51367,N-Hydroxy-N'-acetylbenzidine,Metabolism,NA,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/ATSDR; Toxicological Profile for Benzidine p. 60 (2001),NA
7111,Benzidine,201156,"4,4'-Diamino-3-biphenylyl hydrogen sulfate",Metabolism,NA,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V1 83 (1972)",NA
7111,Benzidine,51366,"N-Hydroxy-N,N'-diacetylbenzidine",Metabolism,"rat, guniea pig and hamster liver cytosol",NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 167 (1982)",NA
7111,Benzidine,54399317,"3-Hydroxy-N,N'-diacetylbenzidine",Metabolism,"rat, guniea pig and hamster liver cytosol",NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V29 167 (1982)",NA
7111,Benzidine,12092052,Benzidine diimine,Metabolism,NA,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10910470,PMID:10910470,NA
7111,Benzidine,128719,Benzidine N-glucuronide,Metabolism,human liver microsomes,NA,948,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7923596,PMID:7923596,NA
7057,2-Naphthylamine,69176,N-Hydroxy-2-naphthylamine,Metabolism,NA,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1062",NA
7057,2-Naphthylamine,69176,N-Hydroxy-2-naphthylamine,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6290305,PMID:6290305,NA
7057,2-Naphthylamine,39038,2-Amino-1-naphthol,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6290305,PMID:6290305,NA
7057,2-Naphthylamine,39038,2-Amino-1-naphthol,Metabolism,rat and rabbit,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Sheftel, V.O.; Indirect Food Additives and Polymers. Migration and Toxicology. Lewis Publishers, Boca Raton, FL. 2000., p. 616",NA
7057,2-Naphthylamine,39038,2-Amino-1-naphthol,Metabolism,NA,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 263",NA
7057,2-Naphthylamine,23098,2-Nitrosonaphthalene,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6290305,PMID:6290305,NA
7057,2-Naphthylamine,90295,6-Amino-1-naphthol,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Tingshu L et al; J Environ Sci (China) 3 (1): 101-8 (1991),NA
7057,2-Naphthylamine,428605,6-Amino-2-naphthalenol,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Tingshu L et al; J Environ Sci (China) 3 (1): 101-8 (1991),NA
7057,2-Naphthylamine,66732,7-Amino-2-naphthol,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Tingshu L et al; J Environ Sci (China) 3 (1): 101-8 (1991),NA
7057,2-Naphthylamine,40116,7-Amino-1-naphthol,Metabolism,rat liver microsomes,NA,1131,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Tingshu L et al; J Environ Sci (China) 3 (1): 101-8 (1991),NA
7017,2-Phenylphenol,14116,Phenylhydroquinone,Metabolism,Human,NA,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 460 (1999)",NA
7017,2-Phenylphenol,14116,Phenylhydroquinone,Metabolism,In vitro,cytochrome P450,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 461 (1999)",NA
7017,2-Phenylphenol,14116,Phenylhydroquinone,Metabolism,NA,NA,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7728964,PMID:7728964,NA
7017,2-Phenylphenol,9688,Phenyl-p-benzoquinone,Metabolism,NA,NA,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10663393,PMID:10663393,NA
7017,2-Phenylphenol,9688,Phenyl-p-benzoquinone,Metabolism,NA,NA,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7728964,PMID:7728964,NA
7017,2-Phenylphenol,123079,"2,4'-Dihydroxybiphenyl",Metabolism,"Rat, Human",NA,1753,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9667081,PMID:9667081,NA
6780,Anthraquinone,11796,2-Hydroxyanthraquinone,Metabolism,Male rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; IUCLID Dataset, Anthraquinone (84-65-1) (2000 CD-ROM  edition). Available from, as of March 27, 2006: https://esis.jrc.ec.europa.eu/",NA
6780,Anthraquinone,11796,2-Hydroxyanthraquinone,Metabolism,rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; IUCLID Dataset, Anthraquinone (84-65-1) (2000 CD-ROM  edition). Available from, as of March 28, 2006: https://esis.jrc.ec.europa.eu/",NA
6780,Anthraquinone,11796,2-Hydroxyanthraquinone,Metabolism,rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-62",NA
6780,Anthraquinone,7018,Anthrone,Metabolism,rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; IUCLID Dataset, Anthraquinone (84-65-1) (2000 CD-ROM  edition). Available from, as of March 28, 2006: https://esis.jrc.ec.europa.eu/",NA
6780,Anthraquinone,7018,Anthrone,Metabolism,rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-62",NA
6780,Anthraquinone,21082,"9,10-Anthracenediol",Metabolism,rat,NA,2074,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-62",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,rat and dog,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Conference of Governmental Industrial Hygienists. Documentation of the TLVs and BEIs with Other World Wide Occupational Exposure Values. 7th Ed. CD-ROM Cincinnati, OH 45240-1634 2013., p. 3",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,"human, guinea pig, rat and dog",NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-87",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,NA,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Health and Environmental Effects Profile, March 1983, p. D-183",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,male Osborne Mendel rats,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 328 (1993)",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,rats and dogs,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11409937,PMID:11409937,NA
6896,"2,6-Dimethylaniline",78101,2-Amino-3-methylbenzoic acid,Metabolism,rats,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 926",NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,human liver,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 926",NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,human,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 327 (1993)",NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,human,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 328 (1993)",NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,male rat liver microsomes,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12019189,PMID:12019189,NA
3676,Lidocaine,6896,"2,6-Dimethylaniline",Metabolism,dairy cows,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:26118443,PMID:26118443,NA
37497,Etidocaine,6896,"2,6-Dimethylaniline",Metabolism,human,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 328 (1993)",NA
47509,Lidamidine hydrochloride,6896,"2,6-Dimethylaniline",Metabolism,human,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 328 (1993)",NA
6896,"2,6-Dimethylaniline",145679,"N-(2,6-dimethylphenyl)hydroxylamine",Metabolism,human and rat,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11409937,PMID:11409937,NA
7005,1-Naphthol,114775,1-Naphthyl sulfate,Metabolism,"rat, rabbit, mouse, guinea pig, fly, and grass grub",NA,2650,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. N-3",NA
7005,1-Naphthol,2115,1-Naphthyl phosphate,Metabolism,fly and in grass grub,NA,2650,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. N-3",NA
7204,(4-Chloro-2-methylphenoxy)acetic acid,14855,4-Chloro-2-methylphenol,Metabolism,arthrobacter sp and flavobacterium peregrinum,NA,1127,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 116",NA
7515,N-Methylaniline,6115,Aniline,Metabolism,rabbit,NA,1654,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-24",NA
7515,N-Methylaniline,5931,4-(Methylamino)phenol,Metabolism,rabbit,NA,1654,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-24",NA
7515,N-Methylaniline,949,"N,N-Dimethylaniline",Metabolism,mycobacterium,NA,1654,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-24",NA
7153,Mecoprop,14855,4-Chloro-2-methylphenol,Metabolism,plants,NA,1738,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hartley, D. and H. Kidd (eds.). The Agrochemicals Handbook. Old Woking, Surrey, United Kingdom: Royal Society of Chemistry/Unwin Brothers Ltd., 1983., p. A255/oct 83",NA
7242,o-Toluidine,17819,4-Amino-3-methylphenol,Metabolism,Male Fischer rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Commission, ESIS; IUCLID Dataset, o-Toluidine (95-53-4) p.94 (2000  CD-ROM edition). Available from, as of May 18, 2010: https://esis.jrc.ec.europa.eu/",NA
7242,o-Toluidine,17819,4-Amino-3-methylphenol,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
7242,o-Toluidine,17819,4-Amino-3-methylphenol,Metabolism,rat,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA/ECAO; Health and Environmental Effects Profile for 2-Methylaniline and 2-Methylaniline Hydrochloride p.20 (1987) ECAO Pub. EPA/600/X-87/092,NA
7242,o-Toluidine,170214,N-(4-Hydroxy-2-methylphenyl)acetamide,Metabolism,Male Fischer rat,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Commission, ESIS; IUCLID Dataset, o-Toluidine (95-53-4) p.94 (2000  CD-ROM edition). Available from, as of May 18, 2010: https://esis.jrc.ec.europa.eu/",NA
7242,o-Toluidine,170214,N-(4-Hydroxy-2-methylphenyl)acetamide,Metabolism,NA,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety; Concise International Chemical Assessment  Document Number 7: o-Toluidine (1998). Available from, as of May 5, 2010: https://www.inchem.org/pages/cicads.html",NA
7242,o-Toluidine,170214,N-(4-Hydroxy-2-methylphenyl)acetamide,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
7242,o-Toluidine,170214,N-(4-Hydroxy-2-methylphenyl)acetamide,Metabolism,human,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Williamson JA et al; J of Analytical Toxicol 19 (4): 256-60 (1995),NA
7242,o-Toluidine,11909,2-Nitrosotoluene,Metabolism,"Mytilus edulis, Crassostrea gigas",NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 4 (4): 435-46 (1985)",NA
7242,o-Toluidine,11909,2-Nitrosotoluene,Metabolism,Abalone,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 5 (4): 387-92 (1986)",NA
7242,o-Toluidine,11909,2-Nitrosotoluene,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
7242,o-Toluidine,69137,N-Methyl-o-toluidine,Metabolism,"Mytilus edulis, Crassostrea gigas",NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 4 (4): 435-46 (1985)",NA
7242,o-Toluidine,7202,"Formamide, N-(2-methylphenyl)-",Metabolism,"Mytilus edulis, Crassostrea gigas",NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 4 (4): 435-46 (1985)",NA
7242,o-Toluidine,11908,N-Hydroxy-2-toluidine,Metabolism,"Mytilus edulis, Crassostrea gigas",NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 4 (4): 435-46 (1985)",NA
7242,o-Toluidine,8443,o-Acetotoluidide,Metabolism,flatfish,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Knezovich JP, Crosby DG; Environ Toxicol Chem 5 (4): 387-92 (1986)",NA
7242,o-Toluidine,8443,o-Acetotoluidide,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
7242,o-Toluidine,227,Anthranilic acid,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
7242,o-Toluidine,3014138,2-Amino-3-methylphenol,Metabolism,Male F344 rats,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Organization for Economic Cooperation and Development; Screening Information Data Set for o-Toluidine (95-53-4) p.129-30 (October,2004). Available from, as of April 28, 2010: https://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html",NA
4906,Prilocaine,7242,o-Toluidine,Metabolism,human,NA,2042,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:17129655,PMID:17129655,NA
8289,Triphenyl phosphate,13282,Diphenyl phosphate,Metabolism,NA,NA,2536,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:25350880,PMID:25350880,NA
8289,Triphenyl phosphate,13282,Diphenyl phosphate,Metabolism,rat liver microsome,NA,2536,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD; Screening Information Data Set (SIDS) Inital Assessment Report for SIDS Initial Assessment Meeting (SIAM) 15, Triphenyl Phosphate (CAS 115-86-6) p.13 (October 2006). Available from, as of February 13, 2018: https://www.inchem.org/pages/sids.html",NA
8295,Tris(2-chloroethyl) phosphate,76438,Bis(2-chloroethyl) phosphate,Metabolism,female rat,NA,2577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1676651,PMID:1676651,NA
8295,Tris(2-chloroethyl) phosphate,76438,Bis(2-chloroethyl) phosphate,Metabolism,male B6C3F1 mice,NA,2577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO; Environ Health Criteria 209: Flame Retardants: Tris(Chloropropyl)Phosphate and Tris(2-chloroethyl) Phosphate (1998). Available from, as of October 10, 2014: https://www.inchem.org/pages/ehc.html",NA
10585,Ethyl benzenesulfonate,7371,Benzenesulfonic Acid,Metabolism,pseudomonas,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-5",NA
7371,Benzenesulfonic Acid,289,Catechol,Metabolism,pseudomonas,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. B-5",NA
7371,Benzenesulfonic Acid,996,Phenol,Metabolism,Pseudomonas sp strain S-313,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3662502,PMID:3662502,NA
7371,Benzenesulfonic Acid,177,Acetaldehyde,Metabolism,bacteria,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5637368,PMID:5637368,NA
7371,Benzenesulfonic Acid,107735,Pyruvate,Metabolism,bacteria,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5637368,PMID:5637368,NA
7371,Benzenesulfonic Acid,5280366,2-Hydroxymuconic semialdehyde,Metabolism,bacteria,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5637368,PMID:5637368,NA
7371,Benzenesulfonic Acid,283,Formate,Metabolism,bacteria,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5637368,PMID:5637368,NA
7371,Benzenesulfonic Acid,124,4-Hydroxy-2-oxopentanoic acid,Metabolism,bacteria,NA,2642,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5637368,PMID:5637368,NA
47866,Cyromazine,7955,Melamine,Metabolism,rat,NA,2648,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Joint FAO/WHO Meeting on Pesticide Residues in Food. FAO Plant Production and Protection Paper 187; Cyromazine p.102 (October 2006) Available from: https://www.fao.org/ag/agp/agpp/Pesticid/Default.htm,NA
14716,2-Ethylhexyl diphenyl phosphate,13282,Diphenyl phosphate,Metabolism,male rat,NA,370,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3377680,PMID:3377680,NA
14716,2-Ethylhexyl diphenyl phosphate,996,Phenol,Metabolism,male rat,NA,370,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3377680,PMID:3377680,NA
14716,2-Ethylhexyl diphenyl phosphate,12793,Phenyl dihydrogen phosphate,Metabolism,male rat,NA,370,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3377680,PMID:3377680,NA
1486,"2,4-Dichlorophenoxyacetic acid",8449,"2,4-Dichlorophenol",Metabolism,NA,NA,1139,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,USEPA; Ambient Water Quality Criteria Doc: Chlorinated Phenols p.A-7 (1980) EPA 440/5-80-032,NA
13450,Terbutryn,146035703,S-Demethyl-desethylterbutryn,Metabolism,rat,NA,1525,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 540",NA
21307,Carboxin,21330,Oxycarboxin,Metabolism,plant,NA,1532,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin CDS, ed. Carboxin (5234-68-4). In: The e-Pesticide Manual, 13th Edition Version 3.0 (2003-04). Surrey UK, British Crop Protection Council.",NA
21307,Carboxin,1983,Acetaminophen,Metabolism,rat,NA,1532,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin CDS, ed. Carboxin (5234-68-4). In: The e-Pesticide Manual, 13th Edition Version 3.0 (2003-04). Surrey UK, British Crop Protection Council.",NA
8427,Dichlorprop,8449,"2,4-Dichlorophenol",Metabolism,plant,NA,1575,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hartley, D. and H. Kidd (eds.). The Agrochemicals Handbook. 2nd ed. Lechworth, Herts, England: The Royal Society of Chemistry, 1987., p. A140/Aug 87",NA
8427,Dichlorprop,8449,"2,4-Dichlorophenol",Metabolism,NA,NA,1575,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Dichlorprop-p (2,4-DP-p) p.12 EPA 738-R-07-008 (August 29, 2007) Available from, as of February 15, 2008: https://www.epa.gov/pesticides/reregistration/status.htm",NA
8427,Dichlorprop,11119,"2,4-Dichloroanisole",Metabolism,NA,NA,1575,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Dichlorprop-p (2,4-DP-p) p.12 EPA 738-R-07-008 (August 29, 2007) Available from, as of February 15, 2008: https://www.epa.gov/pesticides/reregistration/status.htm",NA
8427,Dichlorprop,280,Carbon Dioxide,Metabolism,NA,NA,1575,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Dichlorprop-p (2,4-DP-p) p.12 EPA 738-R-07-008 (August 29, 2007) Available from, as of February 15, 2008: https://www.epa.gov/pesticides/reregistration/status.htm",NA
16850,Fluorescein,123677,Fluorescein glucuronide,Metabolism,NA,NA,2128,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3721789,PMID:3721789,NA
16850,Fluorescein,123677,Fluorescein glucuronide,Metabolism,NA,NA,2128,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Fluorescite (fluorescein sodium) injection, solution (2009). Available from, as of October 19, 2009: https://dailymed.nlm.nih.gov/dailymed/search.cfm?startswith=Fluorescein+sodium",NA
27375,Chlorotoluron,30967,1-(3-Chloro-4-methylphenyl)-3-methylurea,Metabolism,human embryonic lung (HEL) cells,NA,2760,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 552",NA
10303,Methyl red,227,Anthranilic acid,Metabolism,micro organism,NA,2786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-39",NA
10303,Methyl red,7472,"N,N-Dimethyl-p-phenylenediamine",Metabolism,micro organism,NA,2786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. M-39",NA
135401907,Allopurinol,135398752,Oxypurinol,Metabolism,human,NA,3004,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3536254,PMID:3536254,NA
135401907,Allopurinol,135398752,Oxypurinol,Metabolism,human,NA,3004,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:639435,PMID:639435,NA
446598,Clindamycin,11662169,7(S)Chloro-7-deoxylincomycin sulfoxide,Metabolism,NA,NA,3037,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 475",NA
5284603,Oxycodone,5489120,Noroxycodone,Metabolism,NA,NA,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15039299,PMID:15039299,NA
5284603,Oxycodone,5489120,Noroxycodone,Metabolism,NA,CYP3A4,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information Oxycodone Hydrochloride Capsule (June 2017). Available from, as of November 7, 2017: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5df92fed-6194-4905-9ef2-9eed0d2e8086",NA
5284603,Oxycodone,5284604,Oxymorphone,Metabolism,NA,cytochrome P450,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15039299,PMID:15039299,NA
5284603,Oxycodone,5284604,Oxymorphone,Metabolism,NA,NA,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:17525040,PMID:17525040,NA
5284603,Oxycodone,5284604,Oxymorphone,Metabolism,NA,cytochrome P450,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:27692933,PMID:27692933,NA
5284603,Oxycodone,5284604,Oxymorphone,Metabolism,NA,CYP2D6,3142,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information Oxycodone Hydrochloride Capsule (June 2017). Available from, as of November 7, 2017: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5df92fed-6194-4905-9ef2-9eed0d2e8086",NA
156391,Naproxen,162920,Desmethylnaproxen,Metabolism,human,NA,3369,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2170",NA
156391,Naproxen,162920,Desmethylnaproxen,Metabolism,NA,NA,3369,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8218967,PMID:8218967,NA
156391,Naproxen,13393711,O-Desmethylnaproxen,Metabolism,NA,NA,3369,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8218967,PMID:8218967,NA
31645,Pirimicarb,135402388,"2-Amino-5,6-dimethyl-1H-pyrimidin-4-one",Oxidation and Hydrolysis,"Rats, Dogs and Cows",NA,7005,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1170",NA
31645,Pirimicarb,135402388,"2-Amino-5,6-dimethyl-1H-pyrimidin-4-one","Hydrolysis, demethylation",mammals,NA,7005,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:10414785,PMID:10414785,NA
3690,Ifosfamide,7847,Acrolein,Oxidation,Rodents and Dogs,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V26 243 (1981)",NA
3690,Ifosfamide,100427,Palifosfamide,Metabolism,Humans,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11408362,PMID:11408362,NA
3690,Ifosfamide,308171,4-Hydroxyifosfamide,Metabolism,Humans,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11408362,PMID:11408362,NA
3690,Ifosfamide,114861,3-Dechloroethylifosfamide,Metabolism,Humans,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11408362,PMID:11408362,NA
3690,Ifosfamide,114861,3-Dechloroethylifosfamide,Metabolism,Humans,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11488525,PMID:11488525,NA
3690,Ifosfamide,119105,2-Dechloroethylifosfamide,Metabolism,Humans,NA,7023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11488525,PMID:11488525,NA
5533,Trazodone,1355,1-(3-Chlorophenyl)piperazine,Metabolism,NA, P-450 (CYP) 3A4 isoenzyme,7048,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2015; Drug Information 2015. Bethesda, MD. 2015, p. 2382",NA
5533,Trazodone,1355,1-(3-Chlorophenyl)piperazine,Oxidative cleavage,Humans,CYP3A4,7048,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Trazodone Hydrochloride (Trazodone Hydrochloride) Tablet, Film Coated (Updated: August 2015). Available from, as of January 26, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=324d2543-477d-4c0b-bfa0-d76cb4e5cd48",NA
3352,Fipronil,3078139,Fipronil sulfone,Metabolism,Rats,NA,7051,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24016625,PMID:24016625,NA
3352,Fipronil,3078139,Fipronil sulfone,Metabolism,Rats and Humans,NA,7051,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:25687022,PMID:25687022,NA
3352,Fipronil,3078139,Fipronil sulfone,Metabolism,Anodonta woodiana,NA,7051,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:27037470,PMID:27037470,NA
3352,Fipronil,22673275,"5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile",Metabolism,Anodonta woodiana,NA,7051,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:27037470,PMID:27037470,NA
3352,Fipronil,9953940,Fipronil-sulfide,Metabolism,Anodonta woodiana,NA,7051,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:27037470,PMID:27037470,NA
135,4-Hydroxybenzoic acid,126,4-Hydroxybenzaldehyde,Metabolism,Rabbits,NA,7233,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"JECFA; WHO Food Additives Series 48: Safety Evaluation of Certain Food Additives and Contaminants: Hydroxy- and Alkoxy-substituted Benzyl Derivatives (2002). Available from, as of July 23, 2004: https://www.inchem.org/documents/jecfa/jecmono/v48je15.htm",NA
135,4-Hydroxybenzoic acid,151012,4-Hydroxyhippuric acid,Metabolism,Rats,NA,7233,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"JECFA; WHO Food Additives Series 5: Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers and thickening agents (1974). Available from, as of July 23, 2004: https://www.inchem.org/documents/jecfa/jecmono/v05je13.htm",NA
3033,Diclofenac,116545,4'-Hydroxydiclofenac,Hydroxylation,"Humans, rat, rhesus monkey, baboon",NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines and Inspections, Committee for Veterinary Medicinal Products; Diclofenac, Summary Report, p.2 (2003).  Available from, as of October 24, 2011: https://www.ema.europa.eu/ema/index.jsp?curl=/pages/home/Home_Page.jsp&jsenabled=true",NA
3033,Diclofenac,3052567,"4',5-Dihydroxydiclofenac",Hydroxylation,"Humans, rat, rhesus monkey, baboon",NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines and Inspections, Committee for Veterinary Medicinal Products; Diclofenac, Summary Report, p.2 (2003).  Available from, as of October 24, 2011: https://www.ema.europa.eu/ema/index.jsp?curl=/pages/home/Home_Page.jsp&jsenabled=true",NA
3033,Diclofenac,112230,3'-Hydroxydiclofenac,Hydroxylation,Humans,NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 2114",NA
3033,Diclofenac,112230,3'-Hydroxydiclofenac,Hydroxylation,"Humans, rat, rhesus monkey, baboon",NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines and Inspections, Committee for Veterinary Medicinal Products; Diclofenac, Summary Report, p.2 (2003).  Available from, as of October 24, 2011: https://www.ema.europa.eu/ema/index.jsp?curl=/pages/home/Home_Page.jsp&jsenabled=true",NA
3033,Diclofenac,3052566,5-Hydroxydiclofenac,Hydroxylation,Humans,NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 2114",NA
3033,Diclofenac,3052566,5-Hydroxydiclofenac,Hydroxylation,"Humans, rat, rhesus monkey, baboon",NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMEA), The European Agency for the Evaluation of Medicinal Products, Veterinary Medicines and Inspections, Committee for Veterinary Medicinal Products; Diclofenac, Summary Report, p.2 (2003).  Available from, as of October 24, 2011: https://www.ema.europa.eu/ema/index.jsp?curl=/pages/home/Home_Page.jsp&jsenabled=true",NA
3033,Diclofenac,129615,3'-Hydroxy-4'-methoxydiclofenac,"Hydroxylation, 4'-O-methylation",Humans,NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 2114",NA
3899,Leflunomide,54684141,Teriflunomide,N-O bond Cleavage,Humans,p450Fe(II),7289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12975333,PMID:12975333,NA
3899,Leflunomide,9964,4-(Trifluoromethyl)aniline,Metabolism,Humans,NA,7289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Thomson.Micromedex. Drug Information for the  Health Care Professional. 24th ed. Volume 1.  Plus Updates. Content Reviewed by the United States Pharmacopeial Convention, Inc. Greenwood Village, CO. 2004., p. 1758",NA
6128,Androstenedione,222865,Androstanedione,Reduction,Humans,5 alpha-reductase,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bruch HR et al; Journal of Clinical Endocrinology & Metabolism  75: 101-105 (1992),NA
6128,Androstenedione,10635,Androstanolone,Metabolism,HES cells,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18559914,PMID:18559914,NA
6128,Androstenedione,10635,Androstanolone,Metabolism,Bolinus brandaris,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18849009,PMID:18849009,NA
6128,Androstenedione,6013,Testosterone,Metabolism,NA,17 beta-hydroxy steroid dehydrogenase ,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 34-5",NA
6128,Androstenedione,6013,Testosterone,Metabolism,NA,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 35",NA
6128,Androstenedione,6013,Testosterone,Metabolism,HES cells,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18559914,PMID:18559914,NA
6128,Androstenedione,6013,Testosterone,Metabolism,Hexaplex trunculus,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18849009,PMID:18849009,NA
5881,Dehydroepiandrosterone,6128,Androstenedione,Metabolism,NA,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 34-5",NA
6128,Androstenedione,5870,Estrone,Metabolism,Humans,17 beta-hydroxy steroid dehydrogenase/aromatase enzyme complex,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 34-5",NA
6128,Androstenedione,5870,Estrone,Metabolism,Humans,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 35",NA
6128,Androstenedione,5757,Estradiol,Metabolism,Humans,17 beta-hydroxy steroid dehydrogenase/aromatase enzyme complex,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 34-5",NA
6128,Androstenedione,5757,Estradiol,Metabolism,HES cells,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18559914,PMID:18559914,NA
6128,Androstenedione,441301,Androstanediol,Metabolism,HES cells,NA,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18559914,PMID:18559914,NA
68030,"1,1,1,3,3-Pentafluoropropane",6422,Trifluoroacetic Acid,Metabolism,Rat,NA,7508,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12018995,PMID:12018995,NA
2540,Candesartan cilexetil,2541,Candesartan,Hydrolysis,Humans,NA,7520,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Atacand (Candesartan Cilexetil) Tablet (Revised: April 2013). Available from, as of October 9, 2014: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a73e1339-9643-4eea-2cbe-e879c88fb50e",NA
5280863,Kaempferol,127,4-Hydroxyphenylacetic acid,Hydroxylation ,Pig,NA,7703,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:16317785,PMID:16317785,NA
5280863,Kaempferol,359,Phloroglucinol,Hydroxylation ,Pig,NA,7703,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:16317785,PMID:16317785,NA
5280863,Kaempferol,2879,P-Cresol,Hydroxylation ,Pig,NA,7703,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:16317785,PMID:16317785,NA
4168,Metoclopramide,15188246,N-(4-Amino-5-chloro-2-methoxybenzoyl)glycine,Metabolism,NA,NA,7841,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug   Information 2010. Bethesda, MD. (2010), p. 3028",NA
39186,Diltiazem,91638,Deacetyldiltiazem,Metabolism,Humans,NA,6528,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11465404,PMID:11465404,NA
39186,Diltiazem,107891,N-Demethyldiltiazem,Metabolism,Humans,NA,6528,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11465404,PMID:11465404,NA
4171,Metoprolol,114962,alpha-Hydroxymetoprolol,Hydroxylation,Humans,NA,6531,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1770",NA
25429,Carbendazim,115152,Methyl 5-hydroxy-2-benzimidazole carbamate,Metabolism,Rats,NA,6581,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3765661,PMID:3765661,NA
25429,Carbendazim,13624,2-Aminobenzimidazole,Metabolism,Rats,NA,6581,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3765661,PMID:3765661,NA
5656,Venlafaxine,9816723,(+)-O-Desmethylvenlafaxine,O-demethylation,Humans,CYP2D6,6699,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Eap C et al; Pharmacopsychiatry 33(3): p.112-115 (2000),NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Reduction,Liver,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 2492",NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Metabolism,Humans,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Golden RN et al; Arch Gen Psychiatry 45(2): p.145-149 (1988),NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Reduction,Humans,11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1),6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:23804523,PMID:23804523,NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Reduction,Humans,"11beta-hydroxysteroid dehydrogenase 1, AKR1C1, AKR1C2, AKR1C3 and CBR1",6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24088726,PMID:24088726,NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Reduction,Humans and baboons,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:25097227,PMID:25097227,NA
444,Bupropion,51397480,"R,R-threo-hydrobupropion",Metabolism,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Pollock BG et al; Ther Drug Monit 18(5): p.581-585 (1996),NA
444,Bupropion,44229196,"R,S-hydrobupropion",Reduction,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 2492",NA
444,Bupropion,44229196,"R,S-hydrobupropion",Metabolism,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Golden RN et al; Arch Gen Psychiatry 45(2): p.145-149 (1988),NA
444,Bupropion,44229196,"R,S-hydrobupropion",Reduction,Humans ,11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1),6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:23804523,PMID:23804523,NA
444,Bupropion,44229196,"R,S-hydrobupropion",Reduction,Humans ,"11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1), AKR1C1, AKR1C2, AKR1C3 and CBR1",6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24088726,PMID:24088726,NA
444,Bupropion,44229196,"R,S-hydrobupropion",Metabolism,Humans and baboons,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:25097227,PMID:25097227,NA
444,Bupropion,44229196,"R,S-hydrobupropion",Metabolism,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Pollock BG et al; Ther Drug Monit 18(5): p.581-585 (1996),NA
444,Bupropion,446,Hydroxybupropion,Hydroxylation,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 2492",NA
444,Bupropion,446,Hydroxybupropion,Metabolism,Humans ,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Golden RN et al; Arch Gen Psychiatry 45(2): p.145-149 (1988),NA
444,Bupropion,446,Hydroxybupropion,Hydroxylation,Humans ,CYP2B6,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hesse LM et al; Drug Metab Dispos 28(10): p.1176-1183 (2000),NA
444,Bupropion,446,Hydroxybupropion,Hydroxylation,Humans ,CYP2B6,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:23804523,PMID:23804523,NA
444,Bupropion,446,Hydroxybupropion,Oxidation,Humans ,CYP2B6,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24088726,PMID:24088726,NA
444,Bupropion,446,Hydroxybupropion,Metabolism,Humans and baboons,NA,6988,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:25097227,PMID:25097227,NA
5816,Epinephrine,21100,Metanephrine,Metabolism,Liver and Tissues,catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO),4289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 1394",NA
5816,Epinephrine,1245,Vanillylmandelic acid,Metabolism,Liver and Tissues,catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO),4289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 1394",NA
5816,Epinephrine,85782,"3,4-Dihydroxymandelic acid",Metabolism,Liver and Tissues,catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO),4289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 1394",NA
5816,Epinephrine,1292,Mandelic Acid,Metabolism,Liver and Tissues,catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO),4289,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 548",As hydroxyl derivatives of Mandelic acid
13591,N-Nitrosopyrrolidine,25418,N-Nitrosomethylethylamine,Metabolism,Human Bladder,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Nebelin E et al; IARC Sci Publ 41 (N-Nitroso Compd: Occurrence Biol Eff): 473-82 (1982),NA
13591,N-Nitrosopyrrolidine,25418,N-Nitrosomethylethylamine,Metabolism,"Man, rat, mouse, hamster and other animal species",450IIE1,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Yang CS et al; IARC Sci Publ (105): 265-74 (1991),NA
13591,N-Nitrosopyrrolidine,93002,2-Hydroxytetrahydrofuran,alpha-hydroxylation,Rat liver,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:388209,PMID:388209,NA
13591,N-Nitrosopyrrolidine,93002,2-Hydroxytetrahydrofuran,alpha-hydroxylation,Rat liver,microsomes,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:445471,PMID:445471,NA
13591,N-Nitrosopyrrolidine,93002,2-Hydroxytetrahydrofuran,alpha-hydroxylation,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:618576,PMID:618576,NA
13591,N-Nitrosopyrrolidine,8064,"1,4-Butanediol",Metabolism,NA,Postmicrosomal supernatant enzymes,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:445471,PMID:445471,NA
13591,N-Nitrosopyrrolidine,10413,4-Hydroxybutanoic acid,Metabolism,NA,Postmicrosomal supernatant enzymes,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:445471,PMID:445471,NA
13591,N-Nitrosopyrrolidine,6455187,"2-Pyrrolidinol, 1-nitroso-",alpha hydroxylation,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:618576,PMID:618576,NA
107766,alpha-Acetoxy-N-nitrosopyrrolidine,13591,N-Nitrosopyrrolidine,alpha hydroxylation,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:618576,PMID:618576,NA
107766,alpha-Acetoxy-N-nitrosopyrrolidine,13591,N-Nitrosopyrrolidine,alpha hydroxylation,NA,liver esterase,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6825094,PMID:6825094,NA
128280,4-(Carboethoxynitrosamino)butanal,13591,N-Nitrosopyrrolidine,alpha hydroxylation,NA,liver esterase,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6825094,PMID:6825094,NA
13591,N-Nitrosopyrrolidine,7302,gamma-Butyrolactone,Metabolism,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7394792,PMID:7394792,NA
13591,N-Nitrosopyrrolidine,1112,Succinic semialdehyde,Metabolism,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7394792,PMID:7394792,NA
13591,N-Nitrosopyrrolidine,674,Dimethylamine,Metabolism,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7394792,PMID:7394792,NA
13591,N-Nitrosopyrrolidine,1176,Urea,Metabolism,NA,NA,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7394792,PMID:7394792,NA
440917,D-Limonene,1256,Perillic acid,Metabolism,Rats and Rabbits,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/NTP; Toxicology and Carcinogenesis Studies of d-Limonene (Gavage Studies) p. 13 (1990) Technical Rpt Series No. 347 NIH Pub No. 90-2802,NA
440917,D-Limonene,1256,Perillic acid,Metabolism,Humans,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 311 (1999)",NA
440917,D-Limonene,1256,Perillic acid,Metabolism,Rats and Humans,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety; Concise International Chemical Assessment Documents Number 5: Limonene p.11 (1998). Available from, as of February 3, 2006: https://www.inchem.org/pages/cicads.html",NA
440917,D-Limonene,93024,"2-(4-Methylcyclohex-3-en-1-yl)propane-1,2-diol",Metabolism,Dogs,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,DHHS/NTP; Toxicology and Carcinogenesis Studies of d-Limonene (Gavage Studies) p. 13 (1990) Technical Rpt Series No. 347 NIH Pub No. 90-2802,NA
440917,D-Limonene,381256,Dihydroperillic acid,Metabolism,Humans,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 310 (1999)",NA
440917,D-Limonene,441246,"(1S,2S,4R)-Limonene-1,2-diol",Metabolism,Rat,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6992785,PMID:6992785,NA
440917,D-Limonene,7438,Carveol,Metabolism,Dog and Rat,NA,4186,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:969565,PMID:969565,NA
66,"2,5-Dichlorophenol",32819,"3,6-Dichlorocatechol",Metabolism,Rabbits,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. D-22",NA
4685,"1,4-Dichlorobenzene",66,"2,5-Dichlorophenol",Metabolism,NA,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V7 240 (1974)",NA
4685,"1,4-Dichlorobenzene",66,"2,5-Dichlorophenol",Metabolism,Rats,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,KIMURA R ET AL; J PHARMACOBIO-DYN 2 (4): 237 (1979),NA
4685,"1,4-Dichlorobenzene",66,"2,5-Dichlorophenol",Metabolism,Humans,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12399920,PMID:12399920,NA
4685,"1,4-Dichlorobenzene",66,"2,5-Dichlorophenol",Metabolism,Rats,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7900412,PMID:7900412,NA
4685,"1,4-Dichlorobenzene",66,"2,5-Dichlorophenol",Metabolism,male Wistar Rats,NA,4287,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9051121,PMID:9051121,NA
2328,Bentazone,92361,6-Hydroxybentazone,Aryl hydroxylation,Maize,NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gronwald JW, Connelly JA; Pestic Biochem Physiol 40 (3): 284-94 (1991)",NA
2328,Bentazone,92361,6-Hydroxybentazone,Aryl hydroxylation,Soybean (Glycine max Harcor) ,NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Leah JM et al; Pestic Biochem Physiol 39 (3): 232-9 (1991),NA
2328,Bentazone,92361,6-Hydroxybentazone,Metabolism,"Rats, Rabbits and Mouse",NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.37 (2012). Available from, as of October 27, 2017: https://www.who.int/foodsafety/publications/jmpr-monographs/en/",NA
2328,Bentazone,92361,6-Hydroxybentazone,Metabolism,plant,NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.80 (2012). Available from, as of October 27, 2017: https://www.who.int/foodsafety/publications/jmpr-monographs/en/",NA
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",Metabolism,Soybeans,NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 61",NA
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",Metabolism,"Rats, rabbits and mice",NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.37 (2012). Available from, as of October 27, 2017: https://www.who.int/foodsafety/publications/jmpr-monographs/en/",NA
2328,Bentazone,92362,"1H-2,1,3-Benzothiadiazin-4(3H)-one, 8-hydroxy-3-(1-methylethyl)-, 2,2-dioxide",Metabolism,Plant,NA,3430,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Pesticide Residues; Pesticide Residues in Food - 2012, Toxicological Evaluations p.80 (2012). Available from, as of October 27, 2017: https://www.who.int/foodsafety/publications/jmpr-monographs/en/",NA
1001,Phenethylamine,998,Phenylacetaldehyde,Metabolism,Liver,monoamine oxidase ,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15230339,PMID:15230339,NA
1001,Phenethylamine,998,Phenylacetaldehyde,Metabolism,Human,monoamine oxidase B ,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15569272,PMID:15569272,NA
1001,Phenethylamine,999,Phenylacetic Acid,Metabolism,Human,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15230339,PMID:15230339,NA
1001,Phenethylamine,999,Phenylacetic Acid,Metabolism,Human,"aldehyde dehydrogenase, aldehyde oxidase, xanthine oxidase",3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15569272,PMID:15569272,NA
1001,Phenethylamine,6054,2-Phenylethanol,Metabolism,Human,"aldehyde dehydrogenase, aldehyde oxidase, xanthine oxidase",3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15569272,PMID:15569272,NA
6140,Phenylalanine,1001,Phenethylamine,Metabolism,Human,monoamine oxydase type B,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:15589121,PMID:15589121,NA
6140,Phenylalanine,1001,Phenethylamine,Metabolism,Human,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:620466,PMID:620466,NA
3675,Phenelzine,1001,Phenethylamine,Metabolism,Human,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7901780,PMID:7901780,NA
26757,Selegiline,1001,Phenethylamine,Metabolism,Human,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9243353,PMID:9243353,NA
200718,Desmethylselegiline,1001,Phenethylamine,Metabolism,Human,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9243353,PMID:9243353,NA
994,DL-Phenylalanine,1001,Phenethylamine,Decarboxylation,Rat,NA,3526,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9703215,PMID:9703215,NA
5757,Estradiol,5756,Estriol,Metabolism,NA,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1420",NA
5757,Estradiol,5756,Estriol,Metabolism,Dogs,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 (1979)",NA
5757,Estradiol,5756,Estriol,Metabolism,Humans,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,US Natl Inst Health; DailyMed. Current Medication Information estrace (estradiol)  tablet (August 2006).,NA
5757,Estradiol,5870,Estrone,Metabolism,Dogs,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 (1979)",NA
5870,Estrone,5757,Estradiol,Metabolism,Guinea pigs,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 308 (1979)",NA
5870,Estrone,5757,Estradiol,Metabolism,Humans,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,US Natl Inst Health; DailyMed. Current Medication Information estrace (estradiol)  tablet (August 2006).,NA
5757,Estradiol,5870,Estrone,Metabolism,Humans,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,US Natl Inst Health; DailyMed. Current Medication Information estrace (estradiol)  tablet (August 2006).,NA
5757,Estradiol,68570,Alfatradiol,Metabolism,Rabbits,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 308 (1979)",NA
5757,Estradiol,68570,Alfatradiol,Metabolism,"Domestic fowl, bulls and sheep",NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 310 (1979)",NA
5757,Estradiol,20056857,Estrone 3-sulfate,Conjugation,Guinea pigs,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 308 (1979)",NA
5757,Estradiol,3001028,Estrone sulfate,Conjugation,Humans,NA,3589,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,US Natl Inst Health; DailyMed. Current Medication Information estrace (estradiol)  tablet (August 2006).,NA
4929,Prometryn,135461611,2-Hydroxyprometryn,Metabolism,"cotton, soybeans, peanuts, & carrots",NA,4060,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 154",NA
4929,Prometryn,135398733,2-Hydroxyatrazine,Metabolism,"cotton, soybeans, peanuts, & carrots",NA,4060,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 154",NA
4929,Prometryn,135398734,Deisopropylhydroxyatrazine,Metabolism,Rats & rabbits and pea plant,NA,4060,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 318",NA
4929,Prometryn,537563,Prometryn sulfoxide,Metabolism,Pea plant,NA,4060,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 318",NA
6230,Norethindrone,5991,Ethinyl estradiol,Metabolism,Humans,NA,3370,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V91 145 (2007)",NA
5755,Prednisolone,5864,Tetrahydrocortisol,Reduction,Liver,NA,3385,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1446",NA
5755,Prednisolone,5865,Prednisone,Metabolism,Humans,NA,3385,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2069869,PMID:2069869,NA
5994,Progesterone,219833,Pregnanediol,Reduction,Liver,NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug   Information 2010. Bethesda, MD. (2010), p. 3280",NA
5994,Progesterone,219833,Pregnanediol,Metabolism,NA,NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 1439",NA
5994,Progesterone,219833,Pregnanediol,Metabolism,Female chimpanzees (Pan troglodytes),NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 4: A Review of the Literature Published during 1974 and 1975. London: The Chemical Society, 1977., p. 134",NA
5994,Progesterone,31402,Pregnanolone,Metabolism,Female chimpanzees (Pan troglodytes),NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 4: A Review of the Literature Published during 1974 and 1975. London: The Chemical Society, 1977., p. 134",NA
5994,Progesterone,228491,Epipregnanolone,Metabolism,NA,NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for PROCHIEVE (progesterone) gel  (November 2009). Available from, as of March 1, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=13486",NA
5994,Progesterone,9883500,5alpha-Pregnan-3alpha-ol-20-one,Metabolism,NA,NA,3389,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for PROCHIEVE (progesterone) gel  (November 2009). Available from, as of March 1, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=13486",NA
5505,Tolbutamide,74327,4-Methylphenylsulfonylurea,Metabolism,Rat and dogs,NA,3393,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 219",NA
5505,Tolbutamide,6269,P-Toluenesulfonamide,Hydrolysis,Dogs,NA,3393,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 417",NA
5505,Tolbutamide,74327,4-Methylphenylsulfonylurea,Hydrolysis,Dogs,NA,3393,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 417",NA
6013,Testosterone,10635,Androstanolone,Metabolism,NA,NA,3398,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3137",NA
6013,Testosterone,10635,Androstanolone,Reduction,Liver,NA,3398,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3138",NA
6013,Testosterone,5757,Estradiol,Metabolism,NA,NA,3398,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3138",NA
2153,Theophylline,70346,"1,3-Dimethyluric acid",Metabolism,Liver,NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3607",NA
2153,Theophylline,70346,"1,3-Dimethyluric acid",Hydroxylation,Humans,cytochromes P-450 2E1 and P-450 3A3,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Theophylline (Anhydrous) Tablet, Extended Release (Updated: November 2014). Available from, as of July 21, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=038c2b07-8028-4dc4-847c-adafe1b0e81a",NA
2153,Theophylline,70346,"1,3-Dimethyluric acid",ring oxidation and N-demethylation,Humans,cytochromes P-450,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD; Screening Information Data Set (SIDS) Inital Assessment Report for SIDS Initial Assessment Meeting (SIAM) 13, Theophylline (CAS 58-55-9) p.11 (November 2001). Available from, as of July 21, 2016: https://www.inchem.org/pages/sids.html",NA
2153,Theophylline,69726,1-Methyluric acid,Metabolism,Humans,NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3607",NA
2153,Theophylline,69726,1-Methyluric acid,Metabolism,"Rats, Baboons and Mice",NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V51 397 (1991)",NA
2153,Theophylline,69726,1-Methyluric acid,ring oxidation and N-demethylation,Human,cytochrome P-450,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD; Screening Information Data Set (SIDS) Inital Assessment Report for SIDS Initial Assessment Meeting (SIAM) 13, Theophylline (CAS 58-55-9) p.11 (November 2001). Available from, as of July 21, 2016: https://www.inchem.org/pages/sids.html",NA
2153,Theophylline,70639,3-Methylxanthine,Metabolism,Human,NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 3607",NA
2153,Theophylline,70639,3-Methylxanthine,Metabolism,"Rats, Baboons and Mice",NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V51 397 (1991)",NA
2153,Theophylline,70639,3-Methylxanthine,Ring oxidation and N-demethylation,Humans,cytochrome P-450,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD; Screening Information Data Set (SIDS) Inital Assessment Report for SIDS Initial Assessment Meeting (SIAM) 13, Theophylline (CAS 58-55-9) p.11 (November 2001). Available from, as of July 21, 2016: https://www.inchem.org/pages/sids.html",NA
2153,Theophylline,80220,1-Methylxanthine,Demethylation,Humans,cytochrome P-450 1A2,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Theophylline (Anhydrous) Tablet, Extended Release (Updated: November 2014). Available from, as of July 21, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=038c2b07-8028-4dc4-847c-adafe1b0e81a",NA
4947,Propyl gallate,370,Gallic Acid,Hydrolysis,Pigs and rats,NA,591,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 731",NA
4947,Propyl gallate,370,Gallic Acid,Hydrolysis,"Pigs, rats and rabbits",NA,591,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety/World Health Organization; Food Additives Series 32, Gallates (1993). Available from, as of October 10, 2016: https://www.inchem.org/documents/jecfa/jecmono/v32je02.htm",NA
4947,Propyl gallate,78016,"3,5-Dihydroxy-4-methoxybenzoic acid",Metabolism,Rats and rabbits,NA,591,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"EPA/Office of Prevention, Pesticides, and Toxic Substances; Memorandum: Reassessment of Two Exemptions from the Requirement of a Tolerance For Propyl Gallate (CAS Reg. No. 121-79-9) p. 5 (2005). Available from, as of October 12, 2016: https://www3.epa.gov/",NA
4947,Propyl gallate,1057,Pyrogallol,Metabolism,Rats and rabbits,NA,591,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"EPA/Office of Prevention, Pesticides, and Toxic Substances; Memorandum: Reassessment of Two Exemptions from the Requirement of a Tolerance For Propyl Gallate (CAS Reg. No. 121-79-9) p. 5 (2005). Available from, as of October 12, 2016: https://www3.epa.gov/",NA
6505,Acetyl tributyl citrate,54454045,Acetyl citrate,Metabolism,Rats and rabbits,NA,656,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Johnson W; International Journal of Toxicology 21 (Suppl.2): 1-17 (2002),NA
6505,Acetyl tributyl citrate,14334932,"1,2-Dibutyl citrate",Metabolism,Rats ,NA,656,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Johnson W; International Journal of Toxicology 21 (Suppl.2): 1-17 (2002),NA
6506,Triethyl citrate,311,Citric Acid,Hydrolysis,Rats and humans,NA,729,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Expert Committee on Food Additives. Triethyl citrate (WHO Food Additives Series 19). (April 1979). Available from, as of May 5, 2015: https://www.inchem.org/",NA
7618,Triethanolamine,14223,N-Nitrosodiethanolamine,N-Nitrosation ,Rats ,NA,893,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Int J Toxicol 32 (3 Suppl): 59S-83S (2013). Available from, as of July 26, 2016: https://www.cir-safety.org/ingredients",NA
7618,Triethanolamine,8113,Diethanolamine,Nitrosative cleavage,Rats ,NA,893,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Int J Toxicol 32 (3 Suppl): 59S-83S (2013). Available from, as of July 26, 2016: https://www.cir-safety.org/ingredients",NA
7618,Triethanolamine,8113,Diethanolamine,Cytochrome P450 monooxygenasedependent oxidative N-dealkylation,Rats ,NA,893,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 389 (2000)",NA
7618,Triethanolamine,700,Ethanolamine,Cytochrome P450 monooxygenasedependent oxidative N-dealkylation,Rats ,NA,893,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 389 (2000)",NA
7618,Triethanolamine,3614358,Glyoxylate,Cytochrome P450 monooxygenasedependent oxidative N-dealkylation,Rats ,NA,893,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V77 389 (2000)",NA
3026,Dibutyl Phthalate,1017,Phthalic acid,Metabolism,Rats ,pancreatic lipase,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and  BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-1634  2007.",NA
3026,Dibutyl Phthalate,1017,Phthalic acid,Oxidation,"Rats, baboon and humans",lipase,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NTP/CERHR; Monograph on the Potential Human Reproductive and Developmental Effects of Di-n-Butyl Phthalate (DBP) p. II-9. Available from, as of April 17, 2008: https://cerhr.niehs.nih.gov/evals/index.html",NA
3026,Dibutyl Phthalate,8575,Monobutyl phthalate,Hydrolysis,NA,lipase,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 826",NA
3026,Dibutyl Phthalate,8575,Monobutyl phthalate,Metabolism,NA,NA,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"CDC; Fourth National Report on Human Exposure to Environmental Chemicals, Di-n-butyl Phthalate CAS No. 84-74-2 Di-isobutyl Phthalate CAS No. 84-69-5, p. 265 (2009); Available from, as of March 10, 2015: https://www.cdc.gov/exposurereport",NA
3026,Dibutyl Phthalate,8575,Monobutyl phthalate,Hydrolysis,NA,NA,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Final Report of the Cosmetic Ingredient Review Expert Panel; Final Report on the Safety Assessment of Dibutyl Phthalate, Dimethyl Phthalate, and diethyl phthalate (1985).",NA
3026,Dibutyl Phthalate,8575,Monobutyl phthalate,Metabolism,"Rat, baboon, and humans",lipase,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NTP/CERHR; Monograph on the Potential Human Reproductive and Developmental Effects of Di-n-Butyl Phthalate (DBP) p. II-9. Available from, as of April 17, 2008: https://cerhr.niehs.nih.gov/evals/index.html",NA
3026,Dibutyl Phthalate,263,1-Butanol,Hydrolysis,NA,NA,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V6 826",NA
3026,Dibutyl Phthalate,53435015,Mono(3-carboxypropyl) phthalate,Metabolism,Humans,NA,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"CDC; Fourth National Report on Human Exposure to Environmental Chemicals, Di-n-butyl Phthalate CAS No. 84-74-2 Di-isobutyl Phthalate CAS No. 84-69-5, p. 265 (2009); Available from, as of March 10, 2015: https://www.cdc.gov/exposurereport",NA
8082,Piperidine,7526,N-Nitrosopiperidine,N-Hydroxylation,Rats,NA,114,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. 2nd ed. Volume II: Nitrogen and Phosphorus Solvents. Amsterdam-New York-Oxford: Elsevier, 1990., p. 253",NA
131204,Dexpanthenol,6613,Pantothenic Acid,Metabolism,NA,NA,296,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009)",NA
131204,Dexpanthenol,187,Acetylcholine,Metabolism,NA,NA,296,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Evaluations of Drug Interactions. 1st ed. and supplements. Washington, DC: American Pharmaceutical Assn., 1973, 1974., p. 396",Multiple reaction steps
6613,Pantothenic Acid,187,Acetylcholine,Metabolism,Humans,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,NA,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2000.Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2000 (Plus Supplements)., p. 3316",NA
33032,Glutamic Acid,119,Gamma-Aminobutyric Acid,Metabolism,NA,glutamic acid decarboxylase,490,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12467378,PMID:12467378,NA
1493,"2,4-Dinitrophenol",946,Nitrite,Metabolism,Bacteria,NA,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Ambient Water Quality Criteria Doc: Nitrophenols p.A-9 (1980) EPA 440/5-80-063,NA
1493,"2,4-Dinitrophenol",3613389,2-Amino-4-nitrophenol,Metabolism,"Humans, dogs and Mice",NA,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1195",NA
1493,"2,4-Dinitrophenol",3613389,2-Amino-4-nitrophenol,Metabolism,"Humans, dogs and Mice",Nitroreductases,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Dinitrophenols pp.86,88 (August 1995) Toxic Profiles 64. Available from, as of September 16, 2010: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
1493,"2,4-Dinitrophenol",3417419,4-Amino-2-nitrophenol,Metabolism,"Humans, dogs and Mice",Nitroreductases,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Dinitrophenols pp.86,88 (August 1995) Toxic Profiles 64. Available from, as of September 16, 2010: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
1493,"2,4-Dinitrophenol",7266,"2,4-Diaminophenol",Metabolism,"Humans, dogs and Mice",NA,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1195",NA
1493,"2,4-Dinitrophenol",579937,"2,3-Diaminophenol",Metabolism,Humans,NA,529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"National Research Council. Drinking Water & Health, Volume 4. Washington, DC: National Academy Press, 1981., p. 234",NA
643460,Sorbic Acid,5356793,"trans,trans-Muconic acid",Oxidation,NA,NA,590,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V5 812",NA
8113,Diethanolamine,7767,N-Methyldiethanolamine,Metabolism,Rats,NA,924,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V101 129 (2012)",NA
8640,1-Naphthylamine,14535,1-Amino-2-naphthol,ring hydroxylation,NA,NA,1080,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1060",NA
8640,1-Naphthylamine,14535,1-Amino-2-naphthol,Metabolism,Rats and other mammals,NA,1080,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 225",NA
8640,1-Naphthylamine,17815,4-Amino-1-naphthol,ring hydroxylation,NA,NA,1080,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1060",NA
8640,1-Naphthylamine,17815,4-Amino-1-naphthol,Metabolism,Rats and other mammals,NA,1080,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 225",NA
8640,1-Naphthylamine,30767,1-Nitrosonaphthalene,Metabolism,Dogs,NA,1080,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V4 91 (1974)",NA
525,Malic Acid,444972,Fumaric Acid,Metabolism,"Bacteria, plants and humans",NA,1202,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4942",NA
525,Malic Acid,970,Oxalacetic acid,Oxidation,"Bacteria, plants and humans",NA,1202,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4942",NA
525,Malic Acid,1060,Pyruvic Acid,Metabolism,"Bacteria, plants and humans",malic enzyme,1202,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 4942",NA
9411,Bromacil,100019,3-sec-Butyl-6-methyluracil,Metabolism,Male Rats,NA,1522,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 387",NA
10800,"4,6-Dinitro-O-cresol",5374135,2-Amino-6-methyl-4-nitrophenol,Reduction,Rats and Rabbits,NA,1596,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Commission; Recommendation from the Scientific Committee for Occupational Exposure Limits for 4,6-Dinitro-o-cresol, p.4 (October 2004). Available from, as of June 21, 2018: https://ec.europa.eu/social/home.jsp?langId=en",NA
10800,"4,6-Dinitro-O-cresol",5095842,3-Amino-5-nitrosalicylic acid,Oxidation,Rats ,NA,1596,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/International Programme on Chemical Safety; Environmental Health Criteria 220, Dinitro-ortho-cresol (2000) Available from, as of June 20, 2018: https://www.inchem.org/pages/ehc.html",NA
22311,Limonene,1256,Perillic acid,Metabolism,Humans,NA,1809,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Limonene. Available from, as of February 3, 2006: https://www.epa.gov/hpv/pubs/hpvrstp.htm",NA
22311,Limonene,381256,Dihydroperillic acid,Metabolism,Humans,NA,1809,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Limonene. Available from, as of February 3, 2006: https://www.epa.gov/hpv/pubs/hpvrstp.htm",NA
22311,Limonene,10819,Perillyl alcohol,Metabolism,Humans,NA,1809,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans. Limonene. Available from, as of February 3, 2006: https://www.epa.gov/hpv/pubs/hpvrstp.htm",NA
22311,Limonene,93024,"2-(4-Methylcyclohex-3-en-1-yl)propane-1,2-diol",Metabolism,Dogs,NA,1809,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:969565,PMID:969565,NA
8593,Cinchophen,251606,8-Hydroxy-2-phenylquinoline-4-carboxylic acid,Metabolism,Dogs,NA,2085,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 31",NA
6108,4-Nitrobenzoic acid,978,4-Aminobenzoic acid,Reduction,NA,liver microsomal enzymes,2140,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Hayes, W. J., Jr. Toxicology of Pesticides Baltimore: Williams & Wilkins, 1975., p. 112",NA
7504,Benzylamine,240,Benzaldehyde,Metabolism,NA,liver microsomes,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"BELANGER PM, LALANDE M; MICROSOMES, DRUG OXID, CHEM CARCINOG (INT SYMP MICROSOMES DRUG OXID 4TH) 2: 937-40 (1980)",NA
7504,Benzylamine,240,Benzaldehyde,oxidative deamnination,NA,NA,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12230413,PMID:12230413,NA
7504,Benzylamine,240,Benzaldehyde,oxidative deamnination,Mammals,NA,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:20045461,PMID:20045461,NA
7504,Benzylamine,244,Benzyl Alcohol,Metabolism,NA,liver microsomes,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"BELANGER PM, LALANDE M; MICROSOMES, DRUG OXID, CHEM CARCINOG (INT SYMP MICROSOMES DRUG OXID 4TH) 2: 937-40 (1980)",NA
7504,Benzylamine,243,Benzoic Acid,Metabolism,NA,liver microsomes,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"BELANGER PM, LALANDE M; MICROSOMES, DRUG OXID, CHEM CARCINOG (INT SYMP MICROSOMES DRUG OXID 4TH) 2: 937-40 (1980)",NA
7504,Benzylamine,464,Hippuric Acid,conjugation,Rats,NA,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12230413,PMID:12230413,NA
7504,Benzylamine,464,Hippuric Acid,Metabolism,Humans,NA,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:698137,PMID:698137,NA
7504,Benzylamine,2331,Benzamide,Metabolism,Rats,P450 2A1 and 2E1,2795,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12230413,PMID:12230413,NA
5959,Chloramphenicol,69745,"(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol",Metabolism,Dogs,NA,3027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 174 (1990)",NA
5959,Chloramphenicol,83960,Chloramphenicol glucuronide,Metabolism,Dogs and goats,NA,3027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 174 (1990)",NA
5959,Chloramphenicol,3035045,Nitrosochloramphenicol,N-oxidation,Rat,NA,3027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 174 (1990)",NA
5959,Chloramphenicol,22536,Dehydrochloramphenicol,Metabolism,NA,NA,3027,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 180 (1990)",NA
3440,Furosemide,76523,4-Chloro-5-sulfamoylanthranilic acid,Metabolism,Humans,NA,3086,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2016; Drug Information 2016. Bethesda, MD. 2016, p. 2831",NA
3658,Hydroxyzine,2678,Cetirizine,Metabolism,Animals,NA,3098,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2630",NA
938,Nicotinic acid,68499,Nicotinuric acid,Metabolism,Humans,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017, p. 1941",NA
938,Nicotinic acid,68499,Nicotinuric acid,Metabolism,rats,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): p.9 (2005). Available from, as of July 23, 2018: https://www.cir-safety.org/ingredients",NA
938,Nicotinic acid,936,Nicotinamide,Metabolism,Humans,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017, p. 1941",NA
938,Nicotinic acid,936,Nicotinamide,Metabolism,Rats,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): p.8 (2005). Available from, as of July 23, 2018: https://www.cir-safety.org/ingredients",NA
938,Nicotinic acid,5893,Nicotinamide-Adenine-Dinucleotide,Metabolism,Humans,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017, p. 1941",NA
938,Nicotinic acid,64950,N-Methylnicotinamide,Metabolism,Rats,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): p.8 (2005). Available from, as of July 23, 2018: https://www.cir-safety.org/ingredients",NA
938,Nicotinic acid,69698,"1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide",Metabolism,Rats,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): p.8 (2005). Available from, as of July 23, 2018: https://www.cir-safety.org/ingredients",NA
938,Nicotinic acid,440810,"1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide",Metabolism,NA,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review (CIR) Expert Panel; Final Report of the Safety Assessment of Niacinamide and Niacin; Intl J of Toxicology 24 (Suppl 5): p.8 (2005). Available from, as of July 23, 218: https://www.cir-safety.org/ingredients",NA
938,Nicotinic acid,440810,"1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide",Metabolism,Humans,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:135660,PMID:135660,NA
938,Nicotinic acid,160670,"N-Methyl-4-oxo-1,4-dihydropyridine-3-carboxamide",Metabolism,Rats,NA,3134,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24975217,PMID:24975217,NA
4911,Probenecid,1032,Propionic Acid,Metabolism,NA,NA,3387,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals Volume 3. London: The Chemical Society, 1975., p. 288",NA
5339,Sulfasalazine,5336,Sulfapyridine,Cleavage,Humans,NA,3395,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017",NA
5339,Sulfasalazine,4075,Mesalamine,Cleavage,Humans,NA,3395,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017",NA
5339,Sulfasalazine,58638,"Acetamide, N-[4-[(2-pyridinylamino)sulfonyl]phenyl]-",Cleavage/N4-acetylation,Humans,NA,3395,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017",NA
5339,Sulfasalazine,65512,N-Acetyl-5-aminosalicylic acid,Cleavage/N4-acetylation,Humans,NA,3395,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Sulfasalazine tablet, delayed release (Updated: August 2016). Available from, as of April 19, 2017: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=599be7ea-4036-4e43-a411-1c42369b1b8c",NA
134601,Aspartame,5960,Aspartic Acid,Hydrolysis,Monkeys,NA,3915,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4200873,PMID:4200873,NA
134601,Aspartame,5960,Aspartic Acid,Hydrolysis,"Mice, rats, rabbits, dogs, monkeys, and humans",intestinal esterases,3915,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:827618,PMID:827618,NA
134601,Aspartame,6140,Phenylalanine,Hydrolysis,Monkey,NA,3915,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4200873,PMID:4200873,NA
134601,Aspartame,6140,Phenylalanine,Hydrolysis,"Mice, rats, rabbits, dogs, monkeys, and humans",intestinal esterases ,3915,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:827618,PMID:827618,NA
134601,Aspartame,6057,Tyrosine,Hydrolysis,"mice, rats, rabbits, dogs, monkeys, and humans",intestinal esterases ,3915,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:827618,PMID:827618,NA
26229,4-Chlorophenoxyacetic acid,4684,4-Chlorophenol,Metabolism,Arthrobacter,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. C-37",NA
26229,4-Chlorophenoxyacetic acid,16496,4-Chlorocatechol,Metabolism,Pseudomonas,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C. M. Metabolism of Pesticides, An Update. U.S. Department of the Interior, Fish, Wild-life Service, Special Scientific Report - Wildlife No. 184, Washington, DC: U.S. Government Printing Office, l974., p. 131",NA
26229,4-Chlorophenoxyacetic acid,16496,4-Chlorocatechol,Metabolism,Arthrobacter spp,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 207",NA
26229,4-Chlorophenoxyacetic acid,1110,Succinic Acid,Metabolism,Arthrobacter spp,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 207",NA
26229,4-Chlorophenoxyacetic acid,93,3-Oxoadipic acid,Metabolism,Arthrobacter spp,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 207",NA
26229,4-Chlorophenoxyacetic acid,16748825,2-(4-Chloro-2-hydroxyphenoxy)acetic acid,Metabolism,NA,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 119",NA
2724,Chlorphenesin carbamate,26229,4-Chlorophenoxyacetic acid,Metabolism,Dog,NA,3944,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:5971806,PMID:5971806,NA
4764,Phenolphthalein,3032634,Phenolphthalein glucuronide,Metabolism,"Rodents, Dog, guinea pigs",uridine diphosphate glucuronosyltransferase (UDPGT),4161,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V76 399-400 (2000)",NA
5281576,Zearalenone,5933650,Zearalenol,Reduction,Rat,3alpha-hydroxysteroid dehydrogenase,4208,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,OLSEN M ET AL; REDUCTION OF ZEARALENONE TO ZEARALENOL IN FEMALE RAT LIVER BY 3ALPHA-HYDROXYSTEROID DEHYDROGENASE; ACTA PHARMACOL TOXICOL 48(2) 157 (1981),NA
5281576,Zearalenone,5284645,alpha-Zearalenol,Reduction,NA,NA,4208,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,TASHIRO F ET AL; METABOLISM OF ZEARALENONE IN FEMALE RAT LIVER IN VITRO; MAIKOTOKISHIN (TOKYO) 11: 37 (1980),at pH 4.5
5281576,Zearalenone,6437352,beta-Zearalenol,Reduction,NA,NA,4208,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,TASHIRO F ET AL; METABOLISM OF ZEARALENONE IN FEMALE RAT LIVER IN VITRO; MAIKOTOKISHIN (TOKYO) 11: 37 (1980),at pH 7.4
3162,Doxylamine,135338,N-Desmethyldoxylamine,Metabolism,NA,NA,5184,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1975634,PMID:1975634,NA
995,Phenanthrene,7104,3-Hydroxy-2-naphthoic acid,Oxidative metabolism,Pseudomonas aeruginosa,NA,5278,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14342521,PMID:14342521,NA
315482,3-Hydroxy-2-naphthaldehyde,7104,3-Hydroxy-2-naphthoic acid,Oxidative metabolism,Pseudomonas aeruginosa,NA,5278,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14342521,PMID:14342521,NA
7789,12-Hydroxystearic acid,15569771,10-Hydroxyhexadecanoic acid,Metabolism,NA,NA,5368,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,BINDER RG ET AL; HYDROXYSTEARIC ACID DEPOSITION & METABOLISM IN RATS FED HYDROGENATED CASTOR OIL; LIPIDS 5(10) 832 (1970),NA
7789,12-Hydroxystearic acid,14454550,8-Hydroxytetradecanoic acid,Metabolism,NA,NA,5368,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,BINDER RG ET AL; HYDROXYSTEARIC ACID DEPOSITION & METABOLISM IN RATS FED HYDROGENATED CASTOR OIL; LIPIDS 5(10) 832 (1970),NA
643684,Ricinoleic acid,13220191,"Tetrahydro-2,5-furan-diacetic acid",Metabolism,Rats,NA,5634,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate; International Journal of Toxicology 26 (3 Suppl): 31-77 (2007).",NA
643684,Ricinoleic acid,13220194,"3,6-Epoxydecanedioic acid",Metabolism,Rats,NA,5634,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate; International Journal of Toxicology 26 (3 Suppl): 31-77 (2007).",NA
643684,Ricinoleic acid,13220195,6-[2-(2-Hydroxy-2-oxoethyl)tetrahydrofuran-5-yl]hexanoic acid,Metabolism,Rats,NA,5634,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Expert Review Panel; Final Report on the Safety Assessment of Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Glyceryl Ricinoleate, Glyceryl Ricinoleate SE, Ricinoleic Acid, Potassium Ricinoleate, Sodium Ricinoleate, Zinc Ricinoleate, Cetyl Ricinoleate, Ethyl Ricinoleate, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate, and Octyldodecyl Ricinoleate; International Journal of Toxicology 26 (3 Suppl): 31-77 (2007).",NA
5388962,Enalapril,5462501,Enalaprilat,Hydrolysis,"Humans, rats and dogs",NA,6529,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2017; Drug Information 2017. Bethesda, MD. 2017, p. 2090",NA
83975,Tetramethrin,2743,Chrysanthemic acid,ester cleavage/loss of the hydroxymethyl group/reduction/and oxidation ,Rats,NA,6738,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO; Environmental Health Criteria 98: Tetramethrin p.28 (1990),NA
83975,Tetramethrin,78597,"N-Hydroxymethyl-3,4,5,6-tetrahydrophthalimide",Metabolism,Houseflies,NA,6738,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 485",NA
83975,Tetramethrin,34024,"3,4,5,6-Tetrahydrophthalimide",Metabolism,Houseflies,NA,6738,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,WHO; Environmental Health Criteria 98: Tetramethrin p.30 (1990),NA
2764,Ciprofloxacin,128781,Sulfociprofloxacin,Metabolism,NA,NA,6987,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 380",NA
2764,Ciprofloxacin,128242,Oxociprofloxacin,Metabolism,NA,NA,6987,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 380",NA
4235,Moclobemide,1738,Homovanillic acid,Metabolism,NA,NA,7180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 656",NA
4235,Moclobemide,547,"3,4-Dihydroxyphenylacetic acid",Metabolism,NA,NA,7180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 656",NA
4235,Moclobemide,91528,"3,4-Dihydroxyphenylglycol",Metabolism,NA,NA,7180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 656",NA
4235,Moclobemide,1826,5-Hydroxyindole-3-acetic acid,Metabolism,NA,NA,7180,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 656",NA
446157,Rosuvastatin,9956224,N-Desmethyl rosuvastatin,Metabolism,NA,cytochrome P450 \ 2C9,7317,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Crestor (Rosuvastatin Calcium Tablet, Film-Coated) (Updated: May 2016). Available from, as of March 30, 2017: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bb0f3b5e-4bc6-41c9-66b9-6257e2513512",NA
3658,Hydroxyzine,2678,Cetirizine,Metabolism,NA,NA,7739,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:18980631,PMID:18980631,NA
60961,Adenosine,6083,Adenosine Phosphate,Phosphorylation,cytosol,adenosine kinase,7774,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Adenocard (adenosine) (January 2006). Available from, as of October 14, 2009: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=1198",NA
60961,Adenosine,1188,Xanthine,Deamination/degradation,NA,NA,7774,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Adenocard (adenosine) (January 2006). Available from, as of October 14, 2009: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=1198",NA
60961,Adenosine,135398638,Hypoxanthine,Deamination/degradation,NA,NA,7774,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Adenocard (adenosine) (January 2006). Available from, as of October 14, 2009: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=1198",NA
60961,Adenosine,1175,Uric Acid,Deamination/degradation,NA,NA,7774,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Adenocard (adenosine) (January 2006). Available from, as of October 14, 2009: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=1198",NA
864,Thioctic acid,129713215,Dithioloctanoic acid,Metabolism,NA,NA,7818,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 26",NA
864,Thioctic acid,421,Dihydrolipoic acid,Reduction,NA,mitochondrial lipoamide dehydrogenase,7818,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 26",NA
864,Thioctic acid,863,Lipoamide,Metabolism,NA,NA,7818,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR for Nutritional Supplements 2nd ed. Thomson Reuters, Montvale, NJ 2008, p. 26",NA
2314,Bendiocarb,62765,Bendiocarb phenol,Metabolism,Mammals,NA,3918,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tomlin, C.D.S. (ed.). The Pesticide Manual - World Compendium. 10th ed. Surrey, UK: The British Crop Protection Council, 1994., p. 76",NA
798,Indole,50591,1H-Indol-3-ol,Metabolism,"Rat;Rabbit, Chromobacterium",NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. I-3",NA
243,Benzoic Acid,464,Hippuric Acid,Metabolism,Human,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Cosmetic Ingredient Review Expert Panel; International Journal of Toxicology 20 (suppl. 3): 23-50 (2001),NA
243,Benzoic Acid,464,Hippuric Acid,Metabolism,Human,NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety's Concise International Chemical Assessment  Documents. Number 26: Benzoic acid and Sodium Benzoate (2000). Available from, as of March 24, 2005: https://www.inchem.org/pages/cicads.html",NA
243,Benzoic Acid,115145,Benzoyl glucuronide,Metabolism,"Dog, ferret, & hedgehog;indian fruit bat",NA,704,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 2: A Review of the Literature Published Between 1970 and 1971. London: The Chemical Society, 1972., p. 407",NA
980,4-Nitrophenol,403,4-Aminophenol,Metabolism,"rat, bass, carp, catfish, lamprey, perch, pike, salmon, sturgeon;rabbit",NA,1157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. N-18",NA
949,"N,N-Dimethylaniline",5931,4-(Methylamino)phenol,Metabolism,fortified guinea pig hepatic microsomal preparations,cytochrome P450,1179,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"GOODERHAM NJ, GORROD JW; ADV EXP MED BIOL 136B, ISSUE BIOL REACT INTERMED -2, CHEM MECH BIOL EFF PART B: 1109 (1982)",NA
323,Coumarin,5281426,Umbelliferone,Metabolism,human;gerbil,NA,1623,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1496825,PMID:1496825,NA
2519,Caffeine,4687,Paraxanthine,Metabolism,Human;Rat and mouse,NA,36,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"OECD SIDS for Caffeine (CAS 58-08-2); Available from, as of January 9, 2014: https://www.inchem.org/documents/sids/sids/CAFEINE.pdf",NA
3030,Dicamba,82075,5-Hydroxydicamba,Metabolism,wheat and bluegrass plant;barley plants,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 147",NA
3030,Dicamba,66,"2,5-Dichlorophenol",Metabolism,lactating cows;Lactating cow,NA,311,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7193221,PMID:7193221,NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,Rat;Human,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:24172598,PMID:24172598,NA
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",Metabolism,Cunninghamella echinulata;Sugarcane,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 557",NA
3120,Diuron,7257,"3,4-Dichloroaniline",Metabolism,albino rats;dogs,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",NA
3676,Lidocaine,87833,Glycinexylidide,Metabolism,Human,NA,3350,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1697",NA
6896,"2,6-Dimethylaniline",76543,"4-Amino-3,5-dimethylphenol",Metabolism,human liver;rat,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 926",NA
6896,"2,6-Dimethylaniline",78101,2-Amino-3-methylbenzoic acid,Metabolism,male Osborne Mendel rats;male beagle dogs,NA,2094,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V57 328 (1993)",NA
27375,Chlorotoluron,25741,1-(3-Chloro-4-methylphenyl)urea,Metabolism,rat;human embryonic lung (HEL) cells,NA,2760,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 552",NA
3033,Diclofenac,116545,4'-Hydroxydiclofenac,Hydroxylation,Humans,NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 2114",NA
3033,Diclofenac,116545,4'-Hydroxydiclofenac,Hydroxylation,Humans,CYP2C9,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:12438516,PMID:12438516,NA
3033,Diclofenac,3052567,"4',5-Dihydroxydiclofenac",Hydroxylation,Humans,NA,7234,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 2114",NA
6128,Androstenedione,10635,Androstanolone,Reduction;dehydrogenation,Humans,5 alpha-reductase;17 beta- hydroxysteroid dehydrogenase,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bruch HR et al; Journal of Clinical Endocrinology & Metabolism  75: 101-105 (1992),NA
6128,Androstenedione,6013,Testosterone,Dehydrogenation,NA,7 beta- hydroxysteroid dehydrogenase;17 beta- hydroxysteroid dehydrogenase,7335,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bruch HR et al; Journal of Clinical Endocrinology & Metabolism  75: 101-105 (1992),NA
84029,Clarithromycin,84020,14-Hydroxyclarithromycin,oxidative N- demethylation/hydroxylation,Human,NA,8055,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 255",NA
13591,N-Nitrosopyrrolidine,22988675,CID 12025,alpha hydroxylation,NA,liver esterase,5116,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7394792,PMID:7394792,NA
3957,Loratadine,124087,Desloratadine,Decarboxylation,Human liver,"p450 CYP3A4, p450 CYP2D6",3578,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"PDR; Physicians' Desk Reference. 50th Ed. Montvale, NJ: Medical Economics Co. p.2349 (1996)",NA
119392,S-(2-Benzothiazolyl)cysteine,697993,2-Mercaptobenzothiazole,Conjugation,Rat,NA,4025,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1981537,PMID:1981537,NA
2153,Theophylline,70639,3-Methylxanthine,Demethylation,Humans,cytochrome P-450 1A2,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Theophylline (Anhydrous) Tablet, Extended Release (Updated: November 2014). Available from, as of July 21, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=038c2b07-8028-4dc4-847c-adafe1b0e81a",NA
2153,Theophylline,2519,Caffeine,N-methylated,Humans,NA,3399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Theophylline (Anhydrous) Tablet, Extended Release (Updated: November 2014). Available from, as of July 21, 2016: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=038c2b07-8028-4dc4-847c-adafe1b0e81a",NA
3026,Dibutyl Phthalate,1017,Phthalic acid,Hydrolysis/terminal or subterminal oxidation;Oxidation,"Rats ;Rats, male hamsters and guinea pigs",NA,922,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Cosmetic Ingredient Review; Final Report of the Cosmetic Ingredient Review Expert Panel; Final Report on the Safety Assessment of Dibutyl Phthalate, Dimethyl Phthalate, and diethyl phthalate (1985).",NA
22311,Limonene,527143,4-Methyl-beta-methylenecyclohex-3-ene-1-ethanol,Oxidation,Rabbits,NA,1809,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 185",NA
60961,Adenosine,135398641,Inosine,Deamination,humans,adenosine deaminase,7774,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for Adenocard (adenosine) (January 2006). Available from, as of October 14, 2009: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=1198",NA
798,Indole,6305,Tryptophan,Metabolism,"Escherichia, Bacillus, Claviceps;Mycobacterium, Streptomyces;Pea, Nicotiana, Neurospora",NA,599,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. I-3",NA
3120,Diuron,19113,"1-(3,4-Dichlorophenyl)-3-methylurea",Metabolism,albino rats;soybean;dogs,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",NA
3120,Diuron,16854,"1-(3,4-Dichlorophenyl)urea",Metabolism,albino rats;cotton;Dog,NA,382,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 337",NA
13263,Ametryn,157663,ametryne sulfoxide,Metabolism,Rat,NA,1710,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1257",NA
13263,Ametryn,165362571,1-hydroxyisopropylametryn,Metabolism,Rat,NA,1710,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 1257",NA
8418,Anthracene,168354699,"N-acetyl-S-(1,2-dihydro-2-hydroxy-1-anthryl) cysteine",glutathione conjugation,Rat,NA,702,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Chemicals Bureau; European Union Risk Assessment Report, Anthracene (120-12-7) p.40 (2007). Available from, as of February 6, 2017: https://publications.jrc.ec.europa.eu/repository/",NA
6895,"1,2,3-trichlorobenzene",21120873,"n-acetyl-s-(2,3,4-trichlorophenyl)-l-cysteine",Metabolism,Rabbit,NA,1502,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-19",NA
13,"1,2,4-trichlorobenzene",20978542,"3,4,6-trichloro-3,5-cyclohexadiene-1,2-diol",Metabolism,Rat,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6124398,PMID:6124398,NA
13,"1,2,4-trichlorobenzene",7239,o-dichlorobenzene,Metabolism,intestinal contents of rats,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tsuchiya T, Yamaha T; Agric Biol Chem 47 (5): 1163-5 (1983)",NA
13,"1,2,4-trichlorobenzene",10943,m-dichlorobenzene,Metabolism,intestinal contents of rats,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tsuchiya T, Yamaha T; Agric Biol Chem 47 (5): 1163-5 (1983)",NA
13,"1,2,4-trichlorobenzene",4685,p-dichlorobenzene,Metabolism,intestinal contents of rats,NA,1105,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Tsuchiya T, Yamaha T; Agric Biol Chem 47 (5): 1163-5 (1983)",NA
995,Phenanthrene,98490,1-hydroxyphenanthrene,Metabolism,Rat,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",NA
995,Phenanthrene,69061,2-hydroxyphenanthrene,Metabolism,Rat,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",NA
995,Phenanthrene,95724,3-hydroxyphenanthrene,Metabolism,Rat,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",NA
995,Phenanthrene,99889,"trans-9,10-dihydro-9,10-dihydroxyphenanthrene",Metabolism,Rat,NA,2166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. 4",NA
6901,"Hexachlorobuta-1,3-diene",54419367,S-(pentachlorobutadienyl)glutathione,Metabolism,NA,NA,2870,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3176519,PMID:3176519,NA
6901,"Hexachlorobuta-1,3-diene",3014142,"1,1,2,3-tetrachlorobutenoic acid",Metabolism,NA,NA,2870,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3176519,PMID:3176519,NA
31423,Pyrene,168354692,"1-hydroxy-4,5-dihydro-4,5-dihydroxypyrene",Metabolism,Rat liver,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 357",NA
31423,Pyrene,15699,"1,6-pyrene quinone",Metabolism,Rat liver,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. V4 357",NA
31423,Pyrene,9543290,pyrene-1-sulfate,Metabolism,Buccinum undatum,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:20821506,PMID:20821506,NA
31423,Pyrene,74603300,pyrene-1-glucuronide,Metabolism,Buccinum undatum,NA,4023,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:20821506,PMID:20821506,NA
9154,Fluoranthen,3015672,8-hydroxyfluoranthene,Metabolism,Capitella sp. I,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Forbes VE et al; Environ Toxicol Chem 20 (5): 1012-21 (2001),NA
9154,Fluoranthen,176953,3-hydroxyfluoranthene,Metabolism,Capitella sp. I,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Forbes VE et al; Environ Toxicol Chem 20 (5): 1012-21 (2001),NA
9154,Fluoranthen,168354697,7-O-glucuronide-fluoranthene,Metabolism,Solea solea,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hillenweck A et al; Environ Toxicol 27 (12): 2575-81 (2008),NA
9154,Fluoranthen,168354698,8-O-glucuronide-fluoranthene,Metabolism,Solea solea,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hillenweck A et al; Environ Toxicol 27 (12): 2575-81 (2008),NA
9154,Fluoranthen,168354696,"2,3-dihydro-3-hydroxy-2-O-glucuronide-fluoranthene",Metabolism,Solea solea,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hillenweck A et al; Environ Toxicol 27 (12): 2575-81 (2008),NA
9154,Fluoranthen,168354689,"2,3-dihydro-2-hydroxy-3-O-glucuronide-fluoranthene",Metabolism,Solea solea,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hillenweck A et al; Environ Toxicol 27 (12): 2575-81 (2008),NA
9154,Fluoranthen,168354701,"2,3-di-O-glucuronide-fluoranthene",Metabolism,Solea solea,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Hillenweck A et al; Environ Toxicol 27 (12): 2575-81 (2008),NA
9154,Fluoranthen,55048,"2,3-Dihydro-2,3-dihydroxyfluoranthene",Metabolism,rat-liver,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V32 359 (1983)",NA
9154,Fluoranthen,53462463,"2,3-Dihydrofluoranthene-2,3,9-triol",Metabolism,Cunninghamella elegans,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2285310,PMID:2285310,NA
9154,Fluoranthen,53462464,"2,3-Dihydrofluoranthene-2,3,8-triol",Metabolism,Cunninghamella elegans,NA,5486,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2285310,PMID:2285310,NA
37840,BTBPE,90321,"2-(2,4,6-Tribromophenoxy)ethanol",Metabolism,Rat,NA,6099,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14659938,PMID:14659938,NA
135398658,Folic Acid,168354691,N-methyltetrahydrofolic acid,Metabolism,NA,NA,2002,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"McEvoy, G.K. (ed.). American Hospital Formulary Service-  Drug Information 2005. Bethesda, MD: American Society of  Health-System Pharmacists, Inc. 2005 (Plus Supplements)., p. 3522",NA
135401907,Allopurinol,135432358,allopurinol-1-riboside,Metabolism,NA,NA,3004,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6409116,PMID:6409116,NA
135401907,Allopurinol,168354693,allopurinol-1-ribotide,Metabolism,NA,NA,3004,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6409116,PMID:6409116,NA
135398737,Clozapine,137162974,N-oxideclozapine,Metabolism,NA,NA,6478,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Bablenis E et al; Drug Intelligence and Clinical Pharmacy 23 (2): 109-15 (1989),NA
135398737,Clozapine,135508767,"6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-3-ol",Metabolism,Human,NA,6478,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Stock B et al; Arzneim Forsch 27 (5): 982-90 (1977),NA
135398737,Clozapine,135508765,"6-(4-methylpiperazin-1-yl)-3-methylsulfanyl-11H-benzo[b][1,4]benzodiazepine",Metabolism,Human,NA,6478,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,Stock B et al; Arzneim Forsch 27 (5): 982-90 (1977),NA
135398513,Acyclovir,135530051,8-hydroxy-9-(2-hydroxyethoxymethyl)guanine,Metabolism,In Vitro,NA,6511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2013; Drug Information 2013. Bethesda, MD. 2013, p. 769",NA
135511839,Carbadox,168354694,carbadoxaldehyde,Metabolism,In Vitro,NA,7028,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"WHO/FAO; Joint Meeting on Food Additives; Toxicological Evaluation of Certain Veterinary Drug Residues in Food, WHO Food Additive Series 27: Carbadox (1991). Available from, as of November 2, 2015: https://www.inchem.org/pages/jecfa.html",NA
135400189,Vardenafil,168354695,Vardenafil metabolite 1,Metabolism,NA,CYP3A4,7304,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"Thomson.Micromedex. Drug Information for the  Health Care Professional. 24th ed. Volume 1.  Plus Updates. Content Reviewed by the United States Pharmacopeial Convention, Inc. Greenwood Village, CO. 2004.",NA
135398744,Sildenafil,135455980,Desmethylsildenafil,Metabolism,Liver,NA,7305,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1876",NA
135398744,Sildenafil,135539056,Desethylsildenafil,Metabolism,Liver,NA,7305,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"American Society of Health-System Pharmacists 2014; Drug Information 2014. Bethesda, MD. 2014, p. 1876",NA
135398745,Olanzapine,74603552,olanzapine-10-N-glucuronide,Metabolism,NA,NA,8155,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for OLANZAPINE (olanzapine) tablet OLANZAPINE (olanzapine) tablet, orally disintegrating (September 2013). Available from, as of October 21, 2013: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4464f13c-b9b9-4464-a05e-5b2cdc091fb2",NA
135398745,Olanzapine,135446209,4'-N-desmethyl olanzapine,Metabolism,NA,NA,8155,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for OLANZAPINE (olanzapine) tablet OLANZAPINE (olanzapine) tablet, orally disintegrating (September 2013). Available from, as of October 21, 2013: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=4464f13c-b9b9-4464-a05e-5b2cdc091fb2",NA
135415867,Azilsartan,135742018,O-Desethyl Azilsartan,Metabolism,NA,NA,8208,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"NIH; DailyMed. Current Medication Information for Edarbi (Azilsartan Kamedoxomil) Tablet (Revised: October 2012). Available from, as of July 10, 2014: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=75b16bfc-38c1-4133-bd7d-13258d54edec",NA
135449332,Eltrombopag,168354700,Eltrombopag metabolite K,Metabolism,Human liver,NA,8212,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP), CHMP Assessment Report for Revolade (Eltrombopag) p.12 (2010). Available from, as of November 13, 2014: https://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/001110/WC500089967.pdf",NA
135449332,Eltrombopag,162368377,Eltrombopag metabolite G,Metabolism,Human liver,NA,8212,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP), CHMP Assessment Report for Revolade (Eltrombopag) p.12 (2010). Available from, as of November 13, 2014: https://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/001110/WC500089967.pdf",NA
135449332,Eltrombopag,168354690,Eltrombopag metabolite F,Metabolism,Human liver,NA,8212,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP), CHMP Assessment Report for Revolade (Eltrombopag) p.12 (2010). Available from, as of November 13, 2014: https://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_assessment_report/human/001110/WC500089967.pdf",NA
135406868,"s-Triazol-3-ol, 5-nitro-",140455872,"5-amino-1,2,4-triazol-3-one",Metabolism,Rat,NA,8399,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",DOI:10.5281/zenodo.3827487,"ECHA; Registration for 1,2-dihydro-5-nitro-3H-1,2,4-triazol-3-one (CAS 932-64-9); Available from, as of October 24, 2017: https://echa.europa.eu/registration-dossier/-/registered-dossier/5380",NA
196,Adipic Acid,93,3-Oxoadipic acid,Metabolism,Rats,NA,188,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14440268,Rusoff II et al; Toxicol Appl Pharmacol 2 (3): 316-30 (1960),NA
196,Adipic Acid,311,Citric acid,Metabolism,Rats,NA,188,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14440268,Rusoff II et al; Toxicol Appl Pharmacol 2 (3): 316-30 (1960),NA
196,Adipic Acid,612,Lactic acid,Metabolism,Rats,NA,188,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14440268,Rusoff II et al; Toxicol Appl Pharmacol 2 (3): 316-30 (1960),NA
196,Adipic Acid,1176,Urea,Metabolism,Rats,NA,188,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14440268,Rusoff II et al; Toxicol Appl Pharmacol 2 (3): 316-30 (1960),NA
196,Adipic Acid,33032,Glutamic acid,Metabolism,Rats,NA,188,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:14440268,Rusoff II et al; Toxicol Appl Pharmacol 2 (3): 316-30 (1960),NA
241,Benzene,785,Hydroquinone,Metabolism,Microsome,NA,577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"ROSTON DA, KISSINGER PT; ANAL CHEM 54 (11): 1798 (1982)",NA
785,Hydroquinone,4650,"1,4-Benzoquinone",Metabolism,Rats,NA,577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1981544,"Nerland DE, Pierce WM Jr; Drug Metab Dispos 18 (6): 958-61 (1990)",NA
785,Hydroquinone,119474,"N-acetyl-S-(2,5-dihydroxyphenyl)-L-cysteine",Metabolism,Rats,NA,577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1981544,"Nerland DE, Pierce WM Jr; Drug Metab Dispos 18 (6): 958-61 (1990)",NA
785,Hydroquinone,161220,Quinol sulfate,Metabolism,Rats,NA,577,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Divincenzo GD et al; Toxicol 33 (1): 9-18 (1984),NA
2682,Cetyl Alcohol,985,Palmitic Acid,Metabolism,Rats,NA,2643,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 6:494",NA
2907,Cyclophosphamide,7847,Acrolein,Metabolism,Liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 2012",NA
2907,Cyclophosphamide,7847,Acrolein,Metabolism,Human liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1395",NA
2907,Cyclophosphamide,7847,Acrolein,Metabolism,Human and Animals,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7548731,Ramu K et al; Chem Res Toxicol 8 (4): 515-24 (1995),NA
2907,Cyclophosphamide,7847,Acrolein,Metabolism,Human,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11723234,"Schwartz PS, Waxman DJ; Mol Pharmacol 60 (6): 1268-1279 (2001)",NA
2907,Cyclophosphamide,31515,Carboxyphosphamide,Metabolism,Human liver,aldehyde oxidase,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1395",NA
2907,Cyclophosphamide,96356,Phosphoramide mustard,Metabolism,Liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 2012",NA
2907,Cyclophosphamide,96356,Phosphoramide mustard,Metabolism,Human liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1395",NA
2907,Cyclophosphamide,96356,Phosphoramide mustard,Metabolism,Human,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11723234,"Schwartz PS, Waxman DJ; Mol Pharmacol 60 (6): 1268-1279 (2001)",NA
2907,Cyclophosphamide,99735,4-Hydroxycyclophosphamide,Metabolism,Liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 2012",NA
2907,Cyclophosphamide,99735,4-Hydroxycyclophosphamide,Metabolism,Human liver,CYP2B,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1395",NA
2907,Cyclophosphamide,107744,Aldophosphamide,Metabolism,Liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 2012",NA
2907,Cyclophosphamide,107744,Aldophosphamide,Metabolism,Human liver,NA,3047,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 1395",NA
4763,Phenobarbital,9785,4-Hydroxyphenobarbital,Metabolism,NA,NA,3157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009), p. 2584",NA
4763,Phenobarbital,15557863,"5-(3,4-Dihydroxyphenyl)-5-ethylbarbituric acid",Metabolism,Rats and guinea pigs,NA,3157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V13 166 (1977)",NA
4763,Phenobarbital,101623935,Phenobarbital N-glucoside,Metabolism,Neonates,NA,3157,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3383723,"Bhargava VO, Garrettson LK; Dev Pharmacol Ther 11 (1): 8-13 (1988).",NA
5743,Dexamethasone,63050,6beta-Hydroxydexamethasone,Metabolism,Rats,NA,3053,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Joint FAO/WHO Expert Committee on Food Additives; WHO Food Additive Series 33: Toxicological Evaluation of Ceratain Veterinary Drug Residues in Food: Dexamethasone (1994). Available from, as of November 6, 2007: https://www.inchem.org/documents/jecfa/jecmono/v33je09.htm",NA
6101,p-Toluenesulfonic acid,340,3-Methylcatechol,Metabolism,NA,NA,2026,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-17",NA
6101,p-Toluenesulfonic acid,9958,4-Methylcatechol,Metabolism,NA,NA,2026,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-17",NA
6249,Ampicillin,7817,"Piperazine-2,5-dione",Metabolism,NA,NA,3009,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 160",NA
6249,Ampicillin,52921568,Penicilloic acid,Metabolism,NA,NA,3009,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V50 160",NA
6251,Mannitol,2723872,D-Fructose,Metabolism,Aspergillus oryzae,D-Mannitol dehydrogenase,714,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Bergmeyer, H.W. (ed.). Methods of Enzymatic Analysis. 2nd English ed. New York City: Academic Press, 1974., p. 1271",NA
6274,Histidine,774,Histamine,Decarboxylation,NA,NA,1810,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Fenaroli's Handbook of Flavor Ingredients. Volume 2. Edited, translated, and revised by T.E. Furia and N. Bellanca. 2nd ed. Cleveland: The Chemical Rubber Co., 1975., p. 830",NA
7187,Benzoyl Peroxide,243,Benzoic Acid,Metabolism,NA,NA,372,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association, Council on Drugs. AMA Drug Evaluations Annual 1994. Chicago, IL: American Medical Association, 1994., p. 1201",NA
7187,Benzoyl Peroxide,243,Benzoic Acid,Metabolism,Human and Rhesus monkey,NA,372,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:7204686,Nacht S et al; J Am Acad Dermatol 4 (1): 31-7 (1981),NA
7187,Benzoyl Peroxide,243,Benzoic Acid,Metabolism,Mouse,NA,372,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1782351,Swauger JE et al; Chem Res Toxicol 4 (2): 223-8 (1991),NA
7765,"1,1-Diethoxyethane",176,Acetic Acid,Metabolism,Stomach,NA,1635,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Opdyke, D.L.J. (ed.). Monographs on Fragrance Raw Materials. New York: Pergamon Press, 1979., p. 18",NA
7765,"1,1-Diethoxyethane",177,Acetaldehyde,Metabolism,Stomach,NA,1635,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2659",NA
7765,"1,1-Diethoxyethane",702,Ethanol,Metabolism,Stomach,NA,1635,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2659",NA
7909,Methyl isobutyl ketone,7910,4-Methyl-2-pentanol,Metabolism,Mice,NA,148,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Cosmetic Ingredient Review; Safety Assessment of MIBK (Methyl Isobutyl Ketone). Int J Toxicol 23(S1): 29-57 (2003),NA
7909,Methyl isobutyl ketone,7910,4-Methyl-2-pentanol,Metabolism,Mice,NA,148,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8284793,Granvil CP et al; Toxicol Lett 70 (3): 263-7 (1994),NA
7909,Methyl isobutyl ketone,31256,Diacetone Alcohol,Metabolism,Mice,NA,148,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Cosmetic Ingredient Review; Safety Assessment of MIBK (Methyl Isobutyl Ketone). Int J Toxicol 23(S1): 29-57 (2003),NA
7909,Methyl isobutyl ketone,31256,Diacetone Alcohol,Metabolism,Mice,NA,148,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8284793,Granvil CP et al; Toxicol Lett 70 (3): 263-7 (1994),NA
7964,Chlorobenzene,289,Catechol,Metabolism,NA,microsomal enzymes,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,USEPA; Ambient Water Quality Criteria Doc: Chlorinated Benzenes p.C-9 (1980) EPA 440/5-80-028,NA
7964,Chlorobenzene,785,Hydroquinone,Metabolism,"Rats, Mice and Rabbits",NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.25 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
7964,Chlorobenzene,4684,4-Chlorophenol,Metabolism,Humans,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2379965,"Kusters E, Lauwerys R; Int Arch Occup Environ Health 62 (4): 329-31 (1990)",NA
7964,Chlorobenzene,16496,4-Chlorocatechol,Metabolism,Humans,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2379965,"Kusters E, Lauwerys R; Int Arch Occup Environ Health 62 (4): 329-31 (1990)",NA
7964,Chlorobenzene,4684,4-Chlorophenol,Metabolism,Rats,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4066416,"Yoshida M, Hara I; Industrial Health 23 (3): 239-43 (1985)",NA
7964,Chlorobenzene,4684,4-Chlorophenol,Metabolism,Rats,mono-oxygenase,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.24 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
7964,Chlorobenzene,7245,2-Chlorophenol,Metabolism,Rats,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Krewet E et al; Toxicol 59 (1): 67-79 (1989),NA
7964,Chlorobenzene,7933,3-Chlorophenol,Metabolism,Rats,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4066416,"Yoshida M, Hara I; Industrial Health 23 (3): 239-43 (1985)",NA
7964,Chlorobenzene,7245,2-Chlorophenol,Metabolism,Rats,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4066416,"Yoshida M, Hara I; Industrial Health 23 (3): 239-43 (1985)",NA
7964,Chlorobenzene,7933,3-Chlorophenol,Metabolism,Rats,mono-oxygenase,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.24 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
7964,Chlorobenzene,16496,4-Chlorocatechol,Metabolism,Humans,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.25 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
7964,Chlorobenzene,19928,3-Chlorocatechol,Metabolism,"Rats, Mice and Rabbits",NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.25 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
7964,Chlorobenzene,88919,4-Chlorophenylmercapturic acid,Metabolism,Rats,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:4066416,"Yoshida M, Hara I; Industrial Health 23 (3): 239-43 (1985)",NA
7964,Chlorobenzene,88919,4-Chlorophenylmercapturic acid,Metabolism,Humans,NA,55,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"U.S. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Chlorobenzene p.25 (December 1990). Available from, as of July 1 2014: https://www.atsdr.cdc.gov/toxprofiles/index.asp",NA
8103,1-Hexanol,8892,Caproic Acid,Metabolism,Rabbits,alcohol dehydrogenase; aldehyde dehydrogenase,6813,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 6:440",NA
8103,1-Hexanol,8892,Caproic Acid,Metabolism,NA,NA,565,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Snyder, R. (ed.). Ethel Browning's Toxicity and Metabolism of Industrial Solvents. Second Edition. Volume 3 Alcohols and Esters. New York, NY: Elsevier, 1992., p. 179",NA
8441,Dimethyl terephthalate,7489,Terephthalic acid,Metabolism,Rhodococcus species,NA,834,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Ninnekar HZ, Pujar BG; Ind J Biochem Biophys 22 (4): 232-5 (1985)",NA
9215,Acridine,2015,Acridone,Metabolism,Rabbits,NA,634,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-23",NA
12374,"Hexane-1,6-diol",196,Adipic Acid,Metabolism,Rabbits,NA,6488,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Organization for Economic Cooperation and Development; Screening Information Data Set for Hexamethylene glycol, CAS 629-11-8 p.169 (June 2000). Available from, as of June 12, 2017: https://www.inchem.org/pages/sids.html",NA
13342,Vinblastine,197026,Desacetylvinblastine,Metabolism,Liver,NA,3263,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists. AHFS Drug   Information 2008. Bethesda, Maryland 2008, p. 1228",NA
31404,Butylated Hydroxytoluene,107736,"2,6-Di-tert-butyl-4-methylene-2,5-cyclohexadienone",Metabolism,"Rabbits, rat, mice and human",BHT-oxidase,1147,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"European Chemicals Agency (ECHA); Registered Substances, 2,6-di-tert-butyl-p-cresol (CAS Number: 128-37-0) (EC Number: 204-881-4) (Last updated: May 30, 2016). Available from, as of October 17, 2016: https://echa.europa.eu/",NA
31404,Butylated Hydroxytoluene,107736,"2,6-Di-tert-butyl-4-methylene-2,5-cyclohexadienone",Metabolism,Rats,NA,1147,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Takahashi O, Hiraga K; Food Cosmet Toxicol 17 (5): 451 (1979)",NA
31404,Butylated Hydroxytoluene,146102,"2,6-Di-tert-butyl-4-hydroxy-4-methyl-2,5-cyclohexadien-1-one",Metabolism,Rats,NA,1147,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"European Chemicals Agency (ECHA); Registered Substances, 2,6-di-tert-butyl-p-cresol (CAS Number: 128-37-0) (EC Number: 204-881-4) (Last updated: May 30, 2016). Available from, as of October 17, 2016: https://echa.europa.eu/",NA
31703,Doxorubicin,72401,Adriamycinone,Metabolism,NA,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009)",NA
31703,Doxorubicin,83958,7-Deoxydoxorubicinone,Metabolism,NA,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009)",NA
31703,Doxorubicin,83970,Doxorubicinol,Metabolism,NA,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists; AHFS Drug Information 2009. Bethesda, MD. (2009)",NA
31703,Doxorubicin,83970,Doxorubicinol,Metabolism,NA,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Gilman, A.G., T.W. Rall, A.S. Nies and P. Taylor (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 8th ed. New York, NY. Pergamon Press, 1990., p. 1242",NA
31703,Doxorubicin,83970,Doxorubicinol,Metabolism,NA,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Goodman, L.S., and A. Gilman. (eds.) The Pharmacological Basis of Therapeutics. 5th ed. New York: Macmillan Publishing Co., Inc., 1975., p. 1289",NA
31703,Doxorubicin,3081104,7-Deoxydoxorubicinolone,Metabolism,Rats,NA,3070,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-26",NA
36462,Etoposide,46173784,Etoposide glucuronide,Metabolism,Humans,NA,6517,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V76 209 (2000)",NA
171548,Biotin,83814,Biocytin,Metabolism,Humans,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,83833,Biotin sulfoxide,Metabolism,Humans,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,83833,Biotin sulfoxide,Metabolism,NA,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Physicians Desk Reference (PDR) for Nutritional Supplements 1st ed, Medical Economics, Thomson Healthcare; Montvale, NJ p.52 (2001)",NA
171548,Biotin,83863,Biotin sulfone,Metabolism,Humans,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,83863,Biotin sulfone,Metabolism,NA,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Physicians Desk Reference (PDR) for Nutritional Supplements 1st ed, Medical Economics, Thomson Healthcare; Montvale, NJ p.52 (2001)",NA
171548,Biotin,86492,Bisnorbiotin,Metabolism,Mammals,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,86492,Bisnorbiotin,Metabolism,Human,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,86492,Bisnorbiotin,Metabolism,NA,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Physicians Desk Reference (PDR) for Nutritional Supplements 1st ed, Medical Economics, Thomson Healthcare; Montvale, NJ p.52 (2001)",NA
171548,Biotin,71448990,Tetranorbiotin,Metabolism,Mammals,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
171548,Biotin,566344,Biotin D-sulfoxide,Metabolism,Mammals,NA,346,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Coates, P.M., Blackman, M.R., Cragg, G.M., Levine, M., Moss, J., White, J.D. (Ed), Encyclopedia of Dietary Supplements. Marcel Dekker, New York, NY, p. 35 (2005)",NA
444795,Tretinoin,5282379,Isotretinoin,Metabolism,Liver,NA,2169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health-System Pharmacists; Drug Information 2018. Bethesda, MD. 2018, p. 1392",NA
444795,Tretinoin,5282379,Isotretinoin,Metabolism,Humans,NA,2169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Tretinoin Capsule (Updated: January 11, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9c4ae9d9-c2a0-4995-a27a-e3f0f0284db9",NA
444795,Tretinoin,5282379,Isotretinoin,Metabolism,NA,NA,2169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2730336,PMID:2730336,NA
444795,Tretinoin,6437063,All-trans-4-oxoretinoic acid,Metabolism,NA,NA,2169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2730336,PMID:2730336,NA
444795,Tretinoin,6437063,All-trans-4-oxoretinoic acid,Metabolism,Rats,NA,2169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:863728,PMID:863728,NA
445639,Oleic Acid,5281120,Nervonic Acid,Metabolism,Mammals,NA,1240,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 829",NA
445639,Oleic Acid,5312529,Eicosatrienoic acid,Metabolism,Mammals,NA,1240,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 829",NA
5280450,Linoleic Acid,5282948,13-hydroxyoctadecadienoic acid,Metabolism,NA,NA,5200,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:11377374,Sauer LA et al; Biochem Pharmacol 61 (12): 1455-62 (2001),NA
5280450,Linoleic Acid,5282948,13-hydroxyoctadecadienoic acid,Metabolism,NA,NA,5200,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9561154,Horrobin DF et al; Adv Exp Med Biol 433: 291-4 (1997),NA
5280450,Linoleic Acid,5280933,gamma-Linolenic acid,Metabolism,NA,NA,5200,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9561154,Horrobin DF et al; Adv Exp Med Biol 433: 291-4 (1997),NA
5904,Penicillin G,52921568,Penicilloic acid,Metabolism,Human,NA,3166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 95. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1995 (Plus Supplements 1995)., p. 249",NA
5904,Penicillin G,11082,6-Aminopenicillanic acid,Metabolism,Human,NA,3166,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 95. Bethesda, MD: American Society of Hospital Pharmacists, Inc., 1995 (Plus Supplements 1995)., p. 249",NA
66265,Dexfenfluramine,9815618,(S)-Norfenfluramine,Metabolism,Monkeys,NA,7356,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8578770,Caccia S et al; Xenobiotica 25 (10): 1143-50 (1995),NA
66265,Dexfenfluramine,169449382,(S)-N-hydroxynordexfenfluramine,Metabolism,Human,NA,7356,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9825834,Haritos VS et al; Pharmacogenetics (5) :423-32 (1998),Minor metabolite
66265,Dexfenfluramine,9815618,(S)-Norfenfluramine,Metabolism,Human,NA,7356,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:9825834,Haritos VS et al; Pharmacogenetics (5) :423-32 (1998),Major metabolite
6613,Pantothenic Acid,87642,Coenzyme A,Metabolism,NA,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2000.Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2000 (Plus Supplements)., p. 3316",NA
6613,Pantothenic Acid,87642,Coenzyme A,Metabolism,NA,pantothenate kinase,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
87642,Coenzyme A,444485,dephospho CoA,Metabolism,Intestinal lumen,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
87642,Coenzyme A,115254,4'-Phosphopantetheine,Hydrolysis,Intestinal lumen,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
87642,Coenzyme A,439322,Pantetheine,Hydrolysis,Intestinal lumen,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
439322,Pantetheine,6613,Pantothenic Acid,Hydrolysis,Intestinal lumen,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
87642,Coenzyme A,6613,Pantothenic Acid,Metabolism,NA,NA,1020,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NAS, Food and Nutrition Board, Institute of Medicine; Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. National Academy Press, Washington, D.C., pg. 358, 1998. Available from, as of March 2, 2010: https://www.nap.edu/catalog/6015.html",NA
8948,Methylarsonic acid,2513,Cacodylic acid,Metabolism,NA,NA,754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Kearney, P.C., and D. D. Kaufman (eds.) Herbicides: Chemistry, Degredation and Mode of Action. Volumes 1 and 2. 2nd ed. New York: Marcel Dekker, Inc., 1975., p. 755",NA
8948,Methylarsonic acid,167250,Dimethylarsinate,Methylation,Human,NA,754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:6894292,Buchet et al; Int Arch Occup Environ Health 48 (1): 71-9 (1981),NA
8948,Methylarsonic acid,68978,Trimethylarsine,Metabolism,Penicillium brevicaule,NA,754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 40",NA
24883,"1,3-Dichloropropene",7847,Acrolein,Metabolism,Rats,NA,1109,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1643249,Park SB et al; Chem Res Toxicol 5 (2): 193-201 (1992),NA
24883,"1,3-Dichloropropene",560790,2-Chloroacrolein,Metabolism,NA,NA,1109,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:16841964,Eder E et al; Chem Res Toxicol 19 (7): 952-9 (2006),Three steps
24883,"1,3-Dichloropropene",93058,"2,3-Dichloropropanal",Metabolism,Human,NA,1109,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:16841964,Eder E et al; Chem Res Toxicol 19 (7): 952-9 (2006),Two steps
9595287,Oxamyl,2760995,2-(Dimethylamino)-2-oxoacetic acid,Hydrolysis,Rats,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 3. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 1169",Two steps
9595287,Oxamyl,9322,Thiocyanate,Metabolism,Goat,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Li Y et al; Journal of Agric and Food Chem 45 (3): 962-966 (1997),NA
9595287,Oxamyl,185684,2-(Methylamino)-2-oxoacetic acid,Metabolism,Goat,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Li Y et al; Journal of Agric and Food Chem 45 (3): 962-966 (1997),NA
9595287,Oxamyl,10113,Oxamide,Metabolism,Goat,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Li Y et al; Journal of Agric and Food Chem 45 (3): 962-966 (1997),NA
9595287,Oxamyl,89738,Methylethanediamide,Metabolism,Goat,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Li Y et al; Journal of Agric and Food Chem 45 (3): 962-966 (1997),NA
9595287,Oxamyl,6228,"N,N-Dimethylformamide",Hydrolysis,Human,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Que Hee, S. (ed.). Biological Monitoring an Introduction. New York, NY: Van Nostrand Reinhold Co., 1993., p. 495",NA
9595287,Oxamyl,31254,N-Methylformamide,Hydrolysis,Human,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Que Hee, S. (ed.). Biological Monitoring an Introduction. New York, NY: Van Nostrand Reinhold Co., 1993., p. 495",NA
9595287,Oxamyl,713,Formamide,Hydrolysis,Human,NA,6453,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Que Hee, S. (ed.). Biological Monitoring an Introduction. New York, NY: Van Nostrand Reinhold Co., 1993., p. 495",NA
40585,Deltamethrin,9322,Thiocyanate,Oxidation ,Rats,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.41 (1990),Three steps
40585,Deltamethrin,9322,Thiocyanate,Metabolism,NA,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.43 (1990),Multiple steps
40585,Deltamethrin,16526,2-Amino-2-thiazoline-4-carboxylic acid,Metabolism,NA,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.43 (1990),Multiple steps
40585,Deltamethrin,181248,"3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid",Metabolism,Cows,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.45 (1990),NA
40585,Deltamethrin,7420,3-Hydroxybenzoic acid,Metabolism,Hens,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Akhtar MH; J Agric Food Chem 38 (6): 1417-22 (1990),NA
40585,Deltamethrin,38284,3-Phenoxybenzaldehyde,Metabolism,Mice,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.44 (1990),NA
40585,Deltamethrin,19539,3-Phenoxybenzoic acid,Metabolism,Cows,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.45 (1990),NA
40585,Deltamethrin,16526,2-Amino-2-thiazoline-4-carboxylic acid,Oxidation,Rats,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Krieger, R. (ed.). Handbook of Pesticide Toxicology. Volume 2, 2nd ed. 2001. Academic Press, San Diego, California., p. 1270",Three steps
40585,Deltamethrin,26295,(3-Phenoxyphenyl)methanol,Metabolism,Mice,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.44 (1990),NA
40585,Deltamethrin,181248,"3-(2,2-Dibromoethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid",Metabolism,Cows,NA,6604,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,WHO; Environmental Health Criteria 97: Deltamethrin p.45 (1990),NA
36314,Paclitaxel,10056458,6alpha-Hydroxypaclitaxel,Metabolism,NA,CYP2C8,6839,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists. AHFS Drug   Information 2008. Bethesda, Maryland 2008, p. 1188",Major metabolite
36314,Paclitaxel,3081785,3'-p-Hydroxypaclitaxel,Metabolism,NA,CYP3A4,6839,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists. AHFS Drug   Information 2008. Bethesda, Maryland 2008, p. 1188",Minor metabolite
36314,Paclitaxel,158371,"6,3'-p-Dihydroxypaclitaxel",Metabolism,NA,CYP3A4,6839,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health System Pharmacists. AHFS Drug   Information 2008. Bethesda, Maryland 2008, p. 1188",Minor metabolite
36314,Paclitaxel,65366,Baccatin III,Metabolism,Rats,NA,6839,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1981534,Monsarrat B et al; Drug Metab Dispos Biol Fate Chem 18 (6): 895-901 (1990),Minor metabolite
41867,Epirubicin,127118,Epirubicinol,Reduction,NA,NA,6962,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Ellence (Epirubicin Hydrochloride) Injection, Solution (Updated: November 2014). Available from, as of June 16, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a03c798-a652-4895-b29c-3b521a89ba42",NA
41867,Epirubicin,127118,Epirubicinol,"Biotransformation, Metabolism",NA,NA,6962,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8070217,Robert J; Clin Pharmacokinet 26 (6): 428-38 (1994),NA
41867,Epirubicin,83958,7-Deoxydoxorubicinone,"Reduction, Conjugation, Hydrolysis, Redox",NA,NA,6962,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Ellence (Epirubicin Hydrochloride) Injection, Solution (Updated: November 2014). Available from, as of June 16, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a03c798-a652-4895-b29c-3b521a89ba42",Four main metabolic routes
41867,Epirubicin,161952,7-Deoxyadriamycinol aglycone,"Reduction, Conjugation, Hydrolysis, Redox",NA,NA,6962,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Ellence (Epirubicin Hydrochloride) Injection, Solution (Updated: November 2014). Available from, as of June 16, 2015: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a03c798-a652-4895-b29c-3b521a89ba42",Four main metabolic routes
638011,Citral,6375438,"2,6-Octadienedioic acid, 2,6-dimethyl-",Double Omega Oxidation,NA,NA,993,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Patty, F. (ed.). Industrial Hygiene and Toxicology: Volume II: Toxicology. 2nd ed. New York: Interscience Publishers, 1963., p. 1979",
446598,Clindamycin,101276943,N-demethylclindamycin,Metabolism,NA,NA,3037,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 475",
446598,Clindamycin,11662169,Clindamycin Sulfoxide,Metabolism,NA,NA,3037,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Health-System Pharmacists 2012; Drug Information 2012. Bethesda, MD. 2012, p. 475",
644160,DL-Xylose,169019,D-Threitol,Metabolism,Human,NA,3273,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Society of Hospital Pharmacists. Data supplied on contract from American Hospital Formulary Service and other current ASHP sources., p. 1976",
644160,DL-Xylose,6602431,D-xylonic acid,Oxidation,Guinea pig,NA,3273,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Weser E, Laster L; Biochem Med 2 (1): 53-69 (1968)",
5280793,Vitamin D2,5283731,Calcifediol,Hydroxylation,NA,NA,819,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association. AMA Drug Evaluations Annual 1991. Chicago, IL: American Medical Association, 1991., p. 1952",
5280793,Vitamin D2,5280453,"1,25-Dihydroxyvitamin D3",Hydroxylation,NA,NA,819,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"American Medical Association. AMA Drug Evaluations Annual 1991. Chicago, IL: American Medical Association, 1991., p. 1952",
5280793,Vitamin D2,22833566,25-Hydroxyergocalciferol,Metabolism,"Rats, Pig",NA,819,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of  Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse  Station, NJ:  Merck and Co., Inc., 2001., p. 1786",
5280793,Vitamin D2,5311071,Dihydrotachysterol,Reduction,NA,NA,819,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Hardman, J.G., L.E. Limbird, P.B., A.G. Gilman. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 10th ed. New York, NY: McGraw-Hill, 2001., p. 1730",
3032604,Phosphamidon,13134,Dimethyl phosphate,Hydrolysis,Rats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 276",
3032604,Phosphamidon,1004,Phosphoric Acid,Hydrolysis,Rats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 276",
3032604,Phosphamidon,169493192,O-Demethyl phosphamidon,Hydrolysis,Rats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 276",
3032604,Phosphamidon,16206879,Desethylphosphamidon,Metabolism,Bean plants,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 180",
3032604,Phosphamidon,85915,alpha-Chloroacetoacetic acid diethylamide,Metabolism,Bean plants,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 180",
3032604,Phosphamidon,23618221,alpha-Chloroacetoacetic acid ethylamide,Metabolism,Bean plants,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 180",
3032604,Phosphamidon,13134,Dimethyl phosphoric acid,Metabolism,Bean plants,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"White-Stevens, R. (ed.). Pesticides in the Environment: Volume 1, Part 1, Part 2. New York: Marcel Dekker, Inc., 1971., p. 180",
3032604,Phosphamidon,3038082,Phosphamidon amide,Metabolism,Lactating goats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 287",
3032604,Phosphamidon,16206879,Desethylphosphamidon,Metabolism,Lactating goats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 287",
3032604,Phosphamidon,6444652,Dechlorophosphamidon amide,Metabolism,Lactating goats,NA,1754,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"The Chemical Society. Foreign Compound Metabolism in Mammals. Volume 1: A Review of the Literature Published Between 1960 and 1969. London: The Chemical Society, 1970., p. 287",
5283731,Calcifediol,5280453,Calcitriol,Metabolism,Renal,25-hydroxyvitamin D3-1-a-hydroxylase,3482,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Physicians Desk Reference 60th ed, Thomson PDR, Montvale, NJ 2006., p. 411",
5280453,Calcitriol,9910685,"1,24,25-trihydroxyvitamin D3",Metabolism,NA,NA,3482,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service-  Drug Information 2005. Bethesda, MD: American Society of  Health-System Pharmacists, Inc. 2005 (Plus Supplements)., p. 3543",
9547243,Ercalcitriol,9547253,"1,24,25-Trihydroxyergocalciferol",Metabolism,NA,NA,3482,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service-  Drug Information 2005. Bethesda, MD: American Society of  Health-System Pharmacists, Inc. 2005 (Plus Supplements)., p. 3543",
5280453,Calcitriol,9547273,Calcitroic acid,Metabolism,NA,NA,3482,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"McEvoy, G.K. (ed.). American Hospital Formulary Service-  Drug Information 2005. Bethesda, MD: American Society of  Health-System Pharmacists, Inc. 2005 (Plus Supplements)., p. 3543",
5280795,Cholecalciferol,5280453,Calcitriol,Metabolism,Human,NA,3482,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Physicians Desk Reference 60th ed, Thomson PDR, Montvale, NJ 2006., p. 411",
5281743,Retrorsine,6440870,Dehydroretrorsine,Metabolism,Rats,oxidase,3530,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V10 307 (1976)",
5281743,Retrorsine,10198,Retronecine,Metabolism,Rats,NA,3530,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8452478,Chu P et al; Arch Toxicol 67 (1): 39-43 (1993),
5281743,Retrorsine,76972338,Retrorsine N-oxide,Metabolism,Rats,NA,3530,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8452478,Chu P et al; Arch Toxicol 67 (1): 39-43 (1993),
5281743,Retrorsine,6440904,Isatinecic acid,Metabolism,Rats,NA,3530,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:8452478,Chu P et al; Arch Toxicol 67 (1): 39-43 (1993),
5282379,Isotretinoin,444795,Tretinoin,Metabolism,"Mouse, Monkey, Human",NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,Nau H; J Am Acad Dermatol 45 (5): S183-7 (2001),
5282379,Isotretinoin,444795,Tretinoin,Metabolism,Human plasma,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,444795,Tretinoin,Metabolism,Human liver,"CYP2C8, CYP2C9, CYP3A4, CYP2B6",3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,6437087,4-Oxoisotretinoin,Oxidation,Human plasma,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,6437087,4-Oxoisotretinoin,Metabolism,Human liver,"CYP2C8, CYP2C9, CYP3A4, CYP2B6",3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,6437087,4-Oxoisotretinoin,Metabolism,Human blood,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:3478842,"Kochhar DM, Penner JD; Teratology 36 (1): 67-75 (1987)",
5282379,Isotretinoin,6437087,4-Oxoisotretinoin,Oxidation,Cynomolgus monkey,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1676630,Kraft JC et al; Drug Metab Dispos 19 (2): 317-24 (1991),
5282379,Isotretinoin,6437063,All-trans-4-oxoretinoic acid,Oxidation,Human liver,"CYP2C8, CYP2C9, CYP3A4, CYP2B6",3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,6437063,All-trans-4-oxoretinoic acid,Oxidation,Human plasma,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"NIH; DailyMed. Current Medication Information for Isotretinoin Capsule, Liquid Filled (Updated: June 30, 2017). Available from, as of September 13, 2018: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2917c3d-3499-48a0-ba53-120cb979195d",
5282379,Isotretinoin,6437063,All-trans-4-oxoretinoic acid,Oxidation,Cynomolgus monkey,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1676630,Kraft JC et al; Drug Metab Dispos 19 (2): 317-24 (1991),
5282379,Isotretinoin,6439753,13-cis-Retinoyl-beta-glucuronide,Oxidation,Cynomolgus monkey,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1676630,Kraft JC et al; Drug Metab Dispos 19 (2): 317-24 (1991),
5282379,Isotretinoin,5281877,Retinoyl beta-glucuronide,Oxidation,Cynomolgus monkey,NA,3929,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:1676630,Kraft JC et al; Drug Metab Dispos 19 (2): 317-24 (1991),
31269,Carbamoyliminourea,8039,Biurea,Metabolism,NA,NA,1097,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"International Programme on Chemical Safety's Concise International Chemical Assessment Documents. Number 16: Azodicarbonamide (1999). Available from, as of October 27, 2003: https://www.inchem.org/pages/cicads.html",
5462814,Azodicarbonamide,8039,Biurea,Metabolism,NA,NA,1097,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"International Programme on Chemical Safety's Concise International Chemical Assessment Documents. Number 16: Azodicarbonamide (1999). Available from, as of October 27, 2003: https://www.inchem.org/pages/cicads.html",
5364079,Cymoxanil,14075613,(2E)-2-cyano-2-methoxyiminoacetic acid,Metabolism,Rats,NA,6914,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"California Environmental Protection Agency/Department of Pesticide Regulation; Toxicology Data Review Summary for Cymoxanil (57966-95-7). Available from, as of April 17, 2012: https://www.cdpr.ca.gov/docs/risk/toxsums/toxsumlist.htm",
31199,Bomyl,13134,Dimethyl phosphate,Hydrolysis,NA,NA,1588,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 65",
6433156,Trans-Bomyl,13134,Dimethyl phosphate,Hydrolysis,NA,NA,1588,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 65",
6444672,Cis-Bomyl,13134,Dimethyl phosphate,Hydrolysis,NA,NA,1588,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides. U.S. Department of the Interior, Bureau of Sport Fisheries and Wildlife, Publication 127. Washington, DC: U.S. Government Printing Office, 1969., p. 65",
37083,Norgestimate,13109,Norgestrel,Metabolism,NA,NA,7898,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",PMID:2143719,"Stanczyk FZ, Roy S; Contraception 42 (1): 67-96 (1990)",
37083,Norgestimate,13109,Norgestrel,Metabolism,NA,NA,7898,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"US Natl Inst Health; DailyMed. Current Medication Information for MONONESSA (norgestimate and ethinyl estradiol) kit (December 2010).  Available from, as of March 30, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=33976",
37083,Norgestimate,62930,Norelgestromin,Metabolism,NA,NA,7898,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"US Natl Inst Health; DailyMed. Current Medication Information for MONONESSA (norgestimate and ethinyl estradiol) kit (December 2010).  Available from, as of March 30, 2011: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=33976",
11442,Allethrin,5370021,Chrysanthemum dicarboxylic acid,Metabolism,NA,NA,1511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 184",
11442,Allethrin,11083,Allethrolone,Metabolism,NA,NA,1511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Aizawa, H. Metabolic Maps of Pesticides. New York, NY: Academic Press, 1982., p. 184",
11442,Allethrin,11083,Allethrolone,Oxidation,NA,NA,1511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"USEPA/OPPTS; Allethrins: Revised HED Chapter of Reregistration Eligibility Decision Document (RED). p.14 EPA -HQ-OPP-2006-0986-0012 (June 2007). Available from, as of June 9, 2008: https://www.regulations.gov/search/Regs/home.html#home",
11442,Allethrin,2743,Chrysanthemic acid,Metabolism,Housefly,NA,1511,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"Menzie, C.M. Metabolism of Pesticides-Update III. Special Scientific Report- Wildlife No. 232. Washington, DC: U.S.Department of the Interior, Fish and Wildlife Service, 1980., p. 470",
2952,Dantrolene,9577331,5-Hydroxydantrolene,Metabolism,NA,Hepatic mixed function oxidase,3050,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,ARNOLD TH JR ET AL; DANTROLENE SODIUM: URINARY METABOLITES AND HEPATOTOXICITY; RES COMMUN CHEM PATHOL PHARMACOL 39(3) 381 (1983),
2952,Dantrolene,9570289,Aminodantrolene,Metabolism,NA,Nitroreductase,3050,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,ARNOLD TH JR ET AL; DANTROLENE SODIUM: URINARY METABOLITES AND HEPATOTOXICITY; RES COMMUN CHEM PATHOL PHARMACOL 39(3) 381 (1983),
6914273,Dantrolene,9577331,5-Hydroxydantrolene,Metabolism,NA,Hepatic mixed function oxidase,3050,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,ARNOLD TH JR ET AL; DANTROLENE SODIUM: URINARY METABOLITES AND HEPATOTOXICITY; RES COMMUN CHEM PATHOL PHARMACOL 39(3) 381 (1983),
6914273,Dantrolene,9570289,Aminodantrolene,Metabolism,NA,Nitroreductase,3050,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,ARNOLD TH JR ET AL; DANTROLENE SODIUM: URINARY METABOLITES AND HEPATOTOXICITY; RES COMMUN CHEM PATHOL PHARMACOL 39(3) 381 (1983),
9576412,Fenpyroximate,10876220,Fenpyroximate M-8,"Hydrolysis, Oxidation, Hydroxylation, Isomerization, N-demethylation, conjugation",NA,NA,7943,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"WHO/FAO; Joint Meeting on Pesticide Residues Evaluation for Fenpyroximate (134098-61-6) (1995). Available from, as of June 10, 2011: https://www.inchem.org/pages/jmpr.html",
9576412,Fenpyroximate,10876220,Fenpyroximate M-8,metabolism,Rats,NA,7943,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"WHO/FAO; Joint Meeting on Pesticide Residues Evaluation for Fenpyroximate (134098-61-6) (1995). Available from, as of June 10, 2011: https://www.inchem.org/pages/jmpr.html",
9576412,Fenpyroximate,76360,4-(Hydroxymethyl)benzoic acid,metabolism,Rats,NA,7943,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"WHO/FAO; Joint Meeting on Pesticide Residues Evaluation for Fenpyroximate (134098-61-6) (1995). Available from, as of June 10, 2011: https://www.inchem.org/pages/jmpr.html",
9576412,Fenpyroximate,7489,Terephthalic acid,metabolism,NA,NA,7943,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,10.5281/zenodo.3827487,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",,"WHO/FAO; Joint Meeting on Pesticide Residues Evaluation for Fenpyroximate (134098-61-6) (1995). Available from, as of June 10, 2011: https://www.inchem.org/pages/jmpr.html",
7533,Cyclamate,7965,Cyclohexylamine,Human metabolism,Human,,275,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 201 (1999)",
7533,Cyclamate,7966,Cyclohexanol,Metabolism,,,275,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 201 (1999)",
7533,Cyclamate,92886,"trans-1,2-Cyclohexanediol",Metabolism,,,275,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 201 (1999)",
7533,Cyclamate,7582,Dicyclohexylamine,Rat metabolism,Rat,,275,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 202 (1999)",
7533,Cyclamate,7967,Cyclohexanone,Metabolism,Rhesus monkey,,275,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V73 202 (1999)",
2826,Cocaine,644007,Norcocaine,N-demethylation,Animals,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Goldfrank, L.R., Goldfrank's Toxicologic Emergencies 10th Ed. 2015., McGraw-Hill, New York, N.Y., p. 1054",
2826,Cocaine,91460,Ecgonine,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
2826,Cocaine,644006,Cocaethylene,Metabolism in presence of alcohol,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety; Poisons Information Monograph: Cocaine (PIM 139) (1999) Available from, as of October 31, 2017: https://www.inchem.org/pages/pims.html",
2826,Cocaine,448223,Benzoylecgonine,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
2826,Cocaine,104904,Ecgonine methyl ester,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
446220,Cocaine,644007,Norcocaine,N-demethylation,Animals,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Goldfrank, L.R., Goldfrank's Toxicologic Emergencies 10th Ed. 2015., McGraw-Hill, New York, N.Y., p. 1054",
446220,Cocaine,91460,Ecgonine,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
446220,Cocaine,644006,Cocaethylene,Metabolism in presence of alcohol,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"International Programme on Chemical Safety; Poisons Information Monograph: Cocaine (PIM 139) (1999) Available from, as of October 31, 2017: https://www.inchem.org/pages/pims.html",
446220,Cocaine,448223,Benzoylecgonine,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
446220,Cocaine,104904,Ecgonine methyl ester,Metabolism,,,6469,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Dart, R.C. (ed). Medical Toxicology. Third Edition, Lippincott Williams & Wilkins. Philadelphia, PA. 2004., p. 1084",
54678486,Warfarin,54682146,4'-Hydroxywarfarin,Metabolism,,,1786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Krieger, R. (ed.). Handbook of Pesticide Toxicology. Volume 2, 2nd ed. 2001. Academic Press, San Diego, California., p. 1811",
54678486,Warfarin,54697550,8-Hydroxywarfarin,Metabolism,,,1786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,PMID:2568906,Rettie AE et al; Drug Metab Dispos 17 (3): 265-70 (1989),
54678486,Warfarin,54682507,7-Hydroxywarfarin,Metabolism,,,1786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,PMID:2568906,Rettie AE et al; Drug Metab Dispos 17 (3): 265-70 (1989),
54678486,Warfarin,54684422,Dehydrowarfarin,Metabolism,,,1786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for COUMADIN (warfarin sodium) tablet (October 2011). Available from, as of October 29, 2013: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d91934a0-902e-c26c-23ca-d5accc4151b6",
54678486,Warfarin,54692492,10-Hydroxywarfarin,Metabolism,,,1786,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"US Natl Inst Health; DailyMed. Current Medication Information for COUMADIN (warfarin sodium) tablet (October 2011). Available from, as of October 29, 2013: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=d91934a0-902e-c26c-23ca-d5accc4151b6",
5143,Saccharin,69436,2-Sulfamoylbenzoic acid,Metabolism,Monkey,,669,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. S-1",
5143,Saccharin,12438,2-Sulfobenzoic acid,Metabolism,Monkey,,669,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. S-1",
2130,Amantadine,64153,N-Acetylamantadine,Metabolism,,,3202,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11933,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Physicians Desk Reference 60th ed, Thomson PDR, Montvale, NJ 2006., p. 1116",
5756,Estriol,10335195,2-Hydroxyestriol,Metabolism,Human,,3590,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11937,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk  of Chemicals to Humans. Geneva: World Health Organization,  International Agency for Research on Cancer, 1972-PRESENT.  (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V21 336 (1979)",
3374,Flumequine,162938,7-Hydroxyflumequine,Metabolism,,,7034,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11938,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.1093/jac/15.3.337,Schuppan D et al; J Antimicrob Chemother 15 (3): 337-343 (1985),
9810996,Neotame,9815811,"N-(3,3-dimethylbutyl)-L-aspartic acid",Metabolism,,,7965,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11940,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Aikens P, et al; Toxicologist 78 (1-S): 207 (2004)",
9810996,Neotame,14057,"3,3-dimethylbutyric acid",Metabolism,,,7965,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11942,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"WHO/FAO: Expert Committee on Food Additives. Summary of Toxicological Data of Certain Food Additives Series 52: Neotame (165450-17-9) (2004). Available from, as of July 18, 2011: https://www.inchem.org/pages/jecfa.html",
4737,Pentobarbital,94288,3'-Hydroxypentobarbital,Liver metabolism,,,3151,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11944,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"American Society of Hospital Pharmacists. Data supplied on contract from American Hospital Formulary Service and other current ASHP sources., p. 1975",
4909,Primidone,23611,Phenylethylmalonamide,Metabolism,,,3169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11945,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,PMID:9616196,"El-Masri HA, Portier CJ; Drug Metab Dispos 26 (6): 585-94 (1998)",
4909,Primidone,4763,Phenobarbital,Metabolism,,,3169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11946,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,PMID:9616196,"El-Masri HA, Portier CJ; Drug Metab Dispos 26 (6): 585-94 (1998)",
4909,Primidone,9785,4-Hydroxyphenobarbital,Metabolism,,,3169,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11947,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. (Multivolume work). Available at: https://monographs.iarc.fr/ENG/Classification/index.php, p. V108 196 (2016)",
5734,Zonisamide,10467478,N-Acetyl Zonisamide,Metabolism,,,7293,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Physicians Desk Reference. 58th ed. Thomson PDR. Montvale, NJ 2004., p. 1231",
5734,Zonisamide,194588,2-sulfamoylacetyl phenol,Metabolism,,,7293,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,DOI:10.5281/zenodo.3827487,"Physicians Desk Reference. 58th ed. Thomson PDR. Montvale, NJ 2004., p. 1231",
6623,Bisphenol A,83494,MBP,Recombination via radical oxidation of active metabolite,"Rat liver S9 fraction (also human, monkey, mouse)",,513,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,PMID:14691209,Yoshihara S et al; Toxicol Sci 78 (1): 50-9 (2004),
441140,Griseofulvin,161302,6-Demethylgriseofulvin,Metabolism,Animal,,,441140,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"Booth, N.H., L.E. McDonald (eds.). Veterinary Pharmacology and Therapeutics. 5th ed. Ames, Iowa: Iowa State University Press, 1982., p. 776",
441140,Griseofulvin,165367103,6-Demethylgriseofulvin glucuronide,Metabolism,Animal,,,441140,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"Booth, N.H., L.E. McDonald (eds.). Veterinary Pharmacology and Therapeutics. 5th ed. Ames, Iowa: Iowa State University Press, 1982., p. 776",
441140,Griseofulvin,161302,6-Demethylgriseofulvin,Metabolism,Human,,,441140,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 275",
441140,Griseofulvin,165367103,6-Demethylgriseofulvin glucuronide,Metabolism,Human,,,441140,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 275",
441140,Griseofulvin,71317160,Griseofulvic acid,Metabolism,Human,,,441140,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"The Royal Society of Chemistry. Foreign Compound Metabolism in Mammals. Volume 6: A Review of the Literature Published during 1978 and 1979. London: The Royal Society of Chemistry, 1981., p. 275",
68617,Sertraline,114743,N-Desmethylsertraline,Demethylation,Human,,,,HSDB,HSDB is a toxicology database that focuses on the toxicology of potentially hazardous chemicals. See https://pubchem.ncbi.nlm.nih.gov/source/11948,"Transformation Products extracted from HSDB content in PubChem, validated by LCSB-ECI",10.5281/zenodo.3827487,,"Ellenhorn, M.J., S. Schonwald, G. Ordog, J. Wasserberger. Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams and Wilkins, 1997., p. 930",