article_metadata: Michael P Castro Bradford P Whitcomb Deborah A Zajchowski Robert L Coleman
article_metadata: 10.1186/s40661-015-0013-2
article_metadata: Gynecol Oncol Res Pract
article_metadata: 2015 Aug 28;2:4.
article_metadata: clear cell carcinoma genomic kras mutation metformin molecular profiling next generation sequencing ovarian cancer pik3ca mutation personalized medicine precision medicine targeted therapy trametinib
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/27231564/
article_metadata: Case Reports
article_metadata: PMC4880882
article_metadata: 27231564
article_metadata: Successful use of next generation genomic sequencing (NGS)-directed therapy of clear cell carcinoma of the ovary (CCCO) with trametinib and metformin in a patient with chemotherapy-refractory disease
article_metadata: 2015