article_metadata: Jie Zhao Yan Bao Ying Gao Keliang Xie
article_metadata: 10.3389/fimmu.2025.1515602
article_metadata: Front Immunol
article_metadata: 2025 Feb 4:16:1515602.
article_metadata: mda5-dm rp-ild cytokine interferon tofacitinib
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39967677/
article_metadata: Dermatomyositis / drug therapy Dermatomyositis / immunology Interferon-Induced Helicase, IFIH1 / immunology Lung Diseases, Interstitial / drug therapy Lung Diseases, Interstitial / etiology Lung Diseases, Interstitial / immunology Piperidines / therapeutic use Pyrimidines / therapeutic use
article_metadata: Dermatomyositis / drug therapy Dermatomyositis / immunology Interferon-Induced Helicase, IFIH1 / immunology Lung Diseases, Interstitial / drug therapy Lung Diseases, Interstitial / etiology Lung Diseases, Interstitial / immunology Piperidines / therapeutic use Pyrimidines / therapeutic use Case Reports Aged Autoantibodies / blood Autoantibodies / immunology Female Humans Janus Kinase Inhibitors / therapeutic use Protein Kinase Inhibitors / therapeutic use Treatment Outcome tofacitinib Interferon-Induced Helicase, IFIH1 Piperidines IFIH1 protein, human Pyrimidines Janus Kinase Inhibitors Autoantibodies Protein Kinase Inhibitors
article_metadata: PMC11832562
article_metadata: 39967677
article_metadata: Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease
article_metadata: 2025