article_metadata: Timothy J Thauland Laurence Pellerin Robert S Ohgami Rosa Bacchetta Manish J Butte
article_metadata: 10.3389/fimmu.2019.00753
article_metadata: Front Immunol
article_metadata: 2019 Apr 12;10:753.
article_metadata: pi3k t follicular helper cells activated pi3k delta syndrome (apds) osteopontin primary immunodeficiency
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/31031754/
article_metadata: Class I Phosphatidylinositol 3-Kinases / metabolism Primary Immunodeficiency Diseases / diagnosis Primary Immunodeficiency Diseases / etiology T-Lymphocytes, Helper-Inducer / immunology T-Lymphocytes, Helper-Inducer / metabolism
article_metadata: Class I Phosphatidylinositol 3-Kinases / metabolism Primary Immunodeficiency Diseases / diagnosis Primary Immunodeficiency Diseases / etiology T-Lymphocytes, Helper-Inducer / immunology T-Lymphocytes, Helper-Inducer / metabolism Case Reports Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Adolescent Alleles Amino Acid Substitution B-Lymphocytes / immunology B-Lymphocytes / metabolism CD4 Lymphocyte Count Child Class I Phosphatidylinositol 3-Kinases / chemistry Female Humans Immunophenotyping Models, Biological Models, Molecular Mutation Pedigree Protein Conformation Structure-Activity Relationship T-Lymphocyte Subsets / immunology T-Lymphocyte Subsets / metabolism T-Lymphocytes, Helper-Inducer / cytology Class I Phosphatidylinositol 3-Kinases PIK3CD protein, human Activated PI3K-delta Syndrome
article_metadata: PMC6473200
article_metadata: 31031754
article_metadata: Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome
article_metadata: 2019