article_metadata: Maria Chiriaco Gigliola Di Matteo Francesca Conti Davide Petricone Maia De Luca Silvia Di Cesare Cristina Cifaldi Rita De Vito Matteo Zoccolillo Jessica Serafinelli Noemi Poerio Maurizio Fraziano Immacolata Brigida Fabio Cardinale Paolo Rossi Alessandro Aiuti Caterina Cancrini Andrea Finocchi
article_metadata: 10.3389/fimmu.2019.00130
article_metadata: Front Immunol
article_metadata: 2019 Feb 14;10:130.
article_metadata: card9 myd88 ngs primary immune deficiency (pid) pyogenic infections
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/30837984/
article_metadata: CARD Signaling Adaptor Proteins / genetics Dendritic Cells / physiology Epstein-Barr Virus Infections / genetics Herpesvirus 4, Human / physiology Immunoglobulin E / blood Macrophages / immunology Mutation / genetics Myeloid Differentiation Factor 88 / genetics Primary Immunodeficiency Diseases / genetics Viremia / genetics
article_metadata: CARD Signaling Adaptor Proteins / genetics Dendritic Cells / physiology Epstein-Barr Virus Infections / genetics Herpesvirus 4, Human / physiology Immunoglobulin E / blood Macrophages / immunology Mutation / genetics Myeloid Differentiation Factor 88 / genetics Primary Immunodeficiency Diseases / genetics Viremia / genetics Case Reports Research Support, Non-U.S. Gov't Child, Preschool Consanguinity Female High-Throughput Nucleotide Sequencing Homozygote Humans Pedigree CARD Signaling Adaptor Proteins CARD9 protein, human MYD88 protein, human Myeloid Differentiation Factor 88 Immunoglobulin E MYD88 Deficiency
article_metadata: PMC6383679
article_metadata: 30837984
article_metadata: First Case of Patient With Two Homozygous Mutations in MYD88 and CARD9 Genes Presenting With Pyogenic Bacterial Infections, Elevated IgE, and Persistent EBV Viremia
article_metadata: 2019