article_metadata: Eugene Yu-Hin Chan Kyle Ying-Kit Lin Desmond Yat-Hin Yap Alison Lap-Tak Ma
article_metadata: 10.1007/s00467-024-06570-8
article_metadata: Pediatr Nephrol
article_metadata: 2025 Mar;40(3):711-714.
article_metadata: anti-cd20 focal segmental glomerulosclerosis nephrotic syndrome obinutuzumab rituximab
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39466391/
article_metadata: Antibodies, Monoclonal, Humanized / administration & dosage Antibodies, Monoclonal, Humanized / therapeutic use B-Lymphocytes / drug effects B-Lymphocytes / immunology Nephrotic Syndrome / drug therapy Nephrotic Syndrome / immunology Recurrence Rituximab / administration & dosage Rituximab / therapeutic use
article_metadata: Antibodies, Monoclonal, Humanized / administration & dosage Antibodies, Monoclonal, Humanized / therapeutic use B-Lymphocytes / drug effects B-Lymphocytes / immunology Nephrotic Syndrome / drug therapy Nephrotic Syndrome / immunology Recurrence Rituximab / administration & dosage Rituximab / therapeutic use Case Reports Adolescent Drug Resistance Glomerulosclerosis, Focal Segmental / drug therapy Glomerulosclerosis, Focal Segmental / immunology Humans Lymphocyte Depletion / methods Male Treatment Outcome Rituximab Antibodies, Monoclonal, Humanized obinutuzumab
article_metadata: PMC11753364
article_metadata: 39466391
article_metadata: Obinutuzumab as a viable therapeutic strategy in rituximab-refractory childhood frequently relapsing, steroid-dependent nephrotic syndrome that relapsed during B-cell depletion
article_metadata: 2025