article_metadata: Christian Ulrich Huebbers Simon Florian Preuss Jutta Kolligs Julia Vent Markus Stenner Ulrike Wieland Steffi Silling Uta Drebber Ernst-Jan M Speel Jens Peter Klussmann
article_metadata: 10.1371/journal.pone.0057207
article_metadata: PLoS One
article_metadata: 2013;8(2):e57207.
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/23437342/
article_metadata: 3-Hydroxysteroid Dehydrogenases / genetics Carcinoma / genetics Cell Transformation, Neoplastic / genetics Human papillomavirus 6 / genetics Hydroxyprostaglandin Dehydrogenases / genetics Laryngeal Neoplasms / genetics Papilloma / genetics
article_metadata: 3-Hydroxysteroid Dehydrogenases / genetics Carcinoma / genetics Cell Transformation, Neoplastic / genetics Human papillomavirus 6 / genetics Hydroxyprostaglandin Dehydrogenases / genetics Laryngeal Neoplasms / genetics Papilloma / genetics Case Reports Research Support, Non-U.S. Gov't Adult Age of Onset Aldo-Keto Reductase Family 1 Member C3 Carcinoma / pathology Cell Transformation, Neoplastic / pathology Cyclin-Dependent Kinase Inhibitor p16 / genetics Down-Regulation Fatal Outcome Female Human papillomavirus 6 / pathogenicity Humans Laryngeal Neoplasms / pathology Papilloma / pathology Retinoblastoma Protein / genetics Tumor Suppressor Protein p53 / genetics Cyclin-Dependent Kinase Inhibitor p16 Retinoblastoma Protein Tumor Suppressor Protein p53 3-Hydroxysteroid Dehydrogenases Hydroxyprostaglandin Dehydrogenases AKR1C3 protein, human Aldo-Keto Reductase Family 1 Member C3 Laryngeal papillomatosis
article_metadata: PMC3577740
article_metadata: 23437342
article_metadata: Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis
article_metadata: 2013