article_metadata: Blake J McKinley Tucker W Coston Jason S Starr
article_metadata: 10.1093/oncolo/oyae034
article_metadata: Oncologist
article_metadata: 2025 Jan 17;30(1):oyae034.
article_metadata: ret fusion pancreatic neuroendocrine cancer primary resistance selpercatinib
article_metadata: CC BY-NC
article_metadata: https://pubmed.ncbi.nlm.nih.gov/38478398/
article_metadata: Carcinoma, Neuroendocrine / drug therapy Carcinoma, Neuroendocrine / genetics Carcinoma, Neuroendocrine / pathology Drug Resistance, Neoplasm / genetics Pancreatic Neoplasms / drug therapy Pancreatic Neoplasms / genetics Pancreatic Neoplasms / pathology Proto-Oncogene Proteins c-ret / antagonists & inhibitors Proto-Oncogene Proteins c-ret / genetics
article_metadata: Carcinoma, Neuroendocrine / drug therapy Carcinoma, Neuroendocrine / genetics Carcinoma, Neuroendocrine / pathology Drug Resistance, Neoplasm / genetics Pancreatic Neoplasms / drug therapy Pancreatic Neoplasms / genetics Pancreatic Neoplasms / pathology Proto-Oncogene Proteins c-ret / antagonists & inhibitors Proto-Oncogene Proteins c-ret / genetics Case Reports Humans Male Middle Aged Oncogene Proteins, Fusion / antagonists & inhibitors Oncogene Proteins, Fusion / genetics Pyrazoles / pharmacology Pyrazoles / therapeutic use Pyridines Proto-Oncogene Proteins c-ret RET protein, human selpercatinib Oncogene Proteins, Fusion Pyrazoles Pyridines
article_metadata: PMC11783290
article_metadata: 38478398
article_metadata: Primary Resistance to RET Inhibition in a RET Fusion-Positive Pancreatic Neuroendocrine Carcinoma
article_metadata: 2025