article_metadata: Jenny L Wu Wade T Iams
article_metadata: 10.18632/oncotarget.28682
article_metadata: Oncotarget
article_metadata: 2025 Feb 5:16:39-42.
article_metadata: ret rearrangement ros1 rearrangement case report non-small cell lung cancer targeted therapy
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39907599/
article_metadata: Aminopyridines / therapeutic use Carcinoma, Non-Small-Cell Lung / drug therapy Carcinoma, Non-Small-Cell Lung / genetics Carcinoma, Non-Small-Cell Lung / pathology Drug Resistance, Neoplasm / genetics Gene Rearrangement Lactams Lactams, Macrocyclic / therapeutic use Lung Neoplasms / drug therapy Lung Neoplasms / genetics Lung Neoplasms / pathology Protein-Tyrosine Kinases / genetics Proto-Oncogene Proteins c-ret / genetics Proto-Oncogene Proteins / genetics Pyrazoles / therapeutic use
article_metadata: Aminopyridines / therapeutic use Carcinoma, Non-Small-Cell Lung / drug therapy Carcinoma, Non-Small-Cell Lung / genetics Carcinoma, Non-Small-Cell Lung / pathology Drug Resistance, Neoplasm / genetics Gene Rearrangement Lactams Lactams, Macrocyclic / therapeutic use Lung Neoplasms / drug therapy Lung Neoplasms / genetics Lung Neoplasms / pathology Protein-Tyrosine Kinases / genetics Proto-Oncogene Proteins c-ret / genetics Proto-Oncogene Proteins / genetics Pyrazoles / therapeutic use Case Reports Antineoplastic Combined Chemotherapy Protocols / therapeutic use Female High-Throughput Nucleotide Sequencing Humans Male Middle Aged Oncogene Proteins, Fusion / genetics Pyridines Pyrimidines lorlatinib Lactams ROS1 protein, human Lactams, Macrocyclic Aminopyridines Protein-Tyrosine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-ret Pyrazoles Oncogene Proteins, Fusion RET protein, human pralsetinib Pyridines Pyrimidines
article_metadata: PMC11798477
article_metadata: 39907599
article_metadata: Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report
article_metadata: 2025