article_metadata: Hirofumi Watanabe Kodai Enda Fumiyoshi Fujishima Hidekazu Shirota Masashi Ninomiya Tetsuro Yamazaki Hironobu Sasano Takashi Suzuki
article_metadata: 10.1007/s00795-024-00408-w
article_metadata: Med Mol Morphol
article_metadata: 2025 Mar;58(1):83-86.
article_metadata: afp fgfr2 hepatic neuroendocrine neoplasm tp53
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39522069/
article_metadata: Liver Neoplasms / diagnosis Liver Neoplasms / genetics Liver Neoplasms / metabolism Liver Neoplasms / pathology Mutation Neuroendocrine Tumors / diagnosis Neuroendocrine Tumors / genetics Neuroendocrine Tumors / metabolism Neuroendocrine Tumors / pathology Receptor, Fibroblast Growth Factor, Type 2 / genetics Receptor, Fibroblast Growth Factor, Type 2 / metabolism Tumor Suppressor Protein p53 / genetics Tumor Suppressor Protein p53 / metabolism alpha-Fetoproteins / genetics alpha-Fetoproteins / metabolism
article_metadata: Liver Neoplasms / diagnosis Liver Neoplasms / genetics Liver Neoplasms / metabolism Liver Neoplasms / pathology Mutation Neuroendocrine Tumors / diagnosis Neuroendocrine Tumors / genetics Neuroendocrine Tumors / metabolism Neuroendocrine Tumors / pathology Receptor, Fibroblast Growth Factor, Type 2 / genetics Receptor, Fibroblast Growth Factor, Type 2 / metabolism Tumor Suppressor Protein p53 / genetics Tumor Suppressor Protein p53 / metabolism alpha-Fetoproteins / genetics alpha-Fetoproteins / metabolism Case Reports Review Cholangiocarcinoma / diagnosis Cholangiocarcinoma / genetics Cholangiocarcinoma / metabolism Cholangiocarcinoma / pathology Diagnosis, Differential Humans Immunohistochemistry Male Middle Aged Receptor, Fibroblast Growth Factor, Type 2 alpha-Fetoproteins Tumor Suppressor Protein p53 FGFR2 protein, human TP53 protein, human
article_metadata: PMC11829831
article_metadata: 39522069
article_metadata: Primary hepatic alpha-fetoprotein-producing neuroendocrine neoplasm harboring FGFR2 and TP53 mutations: a case report and literature review
article_metadata: 2025