article_metadata: Youjin Oh Joo Hee Park Trie Arni Djunadi Zunairah Shah Liam Il-Young Chung Young Kwang Chae
article_metadata: 10.3389/fendo.2024.1304188
article_metadata: Front Endocrinol (Lausanne)
article_metadata: 2024 Jan 31:15:1304188.
article_metadata: case report immunotherapy mtor inhibitors poorly differentiated thyroid carcinomas treatment outcomes
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/38356955/
article_metadata: Adenocarcinoma / drug therapy Proline / analogs & derivatives Sirolimus / analogs & derivatives Thiocarbamates Thyroid Neoplasms / drug therapy Thyroid Neoplasms / genetics
article_metadata: Adenocarcinoma / drug therapy Proline / analogs & derivatives Sirolimus / analogs & derivatives Thiocarbamates Thyroid Neoplasms / drug therapy Thyroid Neoplasms / genetics Review Case Reports Female Humans Immunotherapy Ipilimumab MTOR Inhibitors Middle Aged Mutation Nivolumab / therapeutic use PTEN Phosphohydrolase / genetics Phosphatidylinositol 3-Kinases / metabolism Proto-Oncogene Proteins c-akt / metabolism TOR Serine-Threonine Kinases / metabolism temsirolimus MTOR Inhibitors Nivolumab Ipilimumab Proto-Oncogene Proteins c-akt Phosphatidylinositol 3-Kinases prolinedithiocarbamate TOR Serine-Threonine Kinases PTEN protein, human PTEN Phosphohydrolase Proline Thiocarbamates Sirolimus
article_metadata: PMC10864638
article_metadata: 38356955
article_metadata: Deep response to a combination of mTOR inhibitor temsirolimus and dual immunotherapy of nivolumab/ipilimumab in poorly differentiated thyroid carcinoma with PTEN mutation: a case report and literature review
article_metadata: 2024