article_metadata: Jiapeng Liu Shuli Hu Haihui Jiang Yong Cui
article_metadata: 10.3389/fimmu.2024.1369972
article_metadata: Front Immunol
article_metadata: 2024 Apr 4:15:1369972.
article_metadata: glioma hypermutation immunologic response immunotherapy temozolomide
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/38690285/
article_metadata: Antineoplastic Agents, Alkylating / therapeutic use Brain Neoplasms / genetics Brain Neoplasms / immunology Brain Neoplasms / therapy Glioma / drug therapy Glioma / genetics Glioma / therapy Mutation Temozolomide / therapeutic use
article_metadata: Antineoplastic Agents, Alkylating / therapeutic use Brain Neoplasms / genetics Brain Neoplasms / immunology Brain Neoplasms / therapy Glioma / drug therapy Glioma / genetics Glioma / therapy Mutation Temozolomide / therapeutic use Case Reports Research Support, Non-U.S. Gov't Adult Fatal Outcome Humans Immunotherapy / methods Male Tumor Microenvironment / immunology Temozolomide Antineoplastic Agents, Alkylating
article_metadata: PMC11059094
article_metadata: 38690285
article_metadata: Case report: Temozolomide induced hypermutation indicates an unfavorable response to immunotherapy in patient with gliomas
article_metadata: 2024