article_metadata: Yasuko Fujisawa Taichi Kitaoka Hiroyuki Ono Shinichi Nakashima Keiichi Ozono Tsutomu Ogata
article_metadata: 10.3389/fendo.2020.590455
article_metadata: Front Endocrinol (Lausanne)
article_metadata: 2020 Dec 18;11:590455.
article_metadata: asfotase alfa dosage reduction hyperphosphatemia hypophosphatasia mild symptoms
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/33391183/
article_metadata: Alkaline Phosphatase / administration & dosage Enzyme Replacement Therapy / methods Hypophosphatasia / therapy Immunoglobulin G / administration & dosage Recombinant Fusion Proteins / administration & dosage Severity of Illness Index
article_metadata: Alkaline Phosphatase / administration & dosage Enzyme Replacement Therapy / methods Hypophosphatasia / therapy Immunoglobulin G / administration & dosage Recombinant Fusion Proteins / administration & dosage Severity of Illness Index Case Reports Research Support, Non-U.S. Gov't Female Humans Hypophosphatasia / enzymology Hypophosphatasia / pathology Infant Prognosis Immunoglobulin G Recombinant Fusion Proteins Alkaline Phosphatase asfotase alfa
article_metadata: PMC7775725
article_metadata: 33391183
article_metadata: Case Report: Efficacy of Reduced Doses of Asfotase Alfa Replacement Therapy in an Infant With Hypophosphatasia Who Lacked Severe Clinical Symptoms
article_metadata: 2020