article_metadata: Guihua Wang Qin Chai Yajie Xiao Wenying Peng Miao Teng Jingyi Wang Hanqing Lin Xiaofan Su Lin Wu
article_metadata: 10.3389/fimmu.2020.607416
article_metadata: Front Immunol
article_metadata: 2021 Jan 28;11:607416.
article_metadata: cd8(+) tumor-infiltrating lymphocytes pd-l1 expression chemo-immunotherapy large cell lung carcinoma predictive biomarker tumor mutational burden
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/33584678/
article_metadata: Antibodies, Monoclonal, Humanized / therapeutic use Antineoplastic Combined Chemotherapy Protocols / therapeutic use B7-H1 Antigen / antagonists & inhibitors CD8-Positive T-Lymphocytes / drug effects Carcinoma, Large Cell / drug therapy Immune Checkpoint Inhibitors / therapeutic use Lung Neoplasms / drug therapy Lymphocytes, Tumor-Infiltrating / drug effects
article_metadata: Antibodies, Monoclonal, Humanized / therapeutic use Antineoplastic Combined Chemotherapy Protocols / therapeutic use B7-H1 Antigen / antagonists & inhibitors CD8-Positive T-Lymphocytes / drug effects Carcinoma, Large Cell / drug therapy Immune Checkpoint Inhibitors / therapeutic use Lung Neoplasms / drug therapy Lymphocytes, Tumor-Infiltrating / drug effects Case Reports Research Support, Non-U.S. Gov't Adult B7-H1 Antigen / metabolism CD8-Positive T-Lymphocytes / immunology CD8-Positive T-Lymphocytes / metabolism Carcinoma, Large Cell / immunology Carcinoma, Large Cell / metabolism Carcinoma, Large Cell / pathology Cisplatin / therapeutic use Humans Lung Neoplasms / immunology Lung Neoplasms / metabolism Lung Neoplasms / pathology Lymphocytes, Tumor-Infiltrating / immunology Lymphocytes, Tumor-Infiltrating / metabolism Male Paclitaxel / therapeutic use Remission Induction Treatment Outcome Tumor Microenvironment Antibodies, Monoclonal, Humanized B7-H1 Antigen CD274 protein, human Immune Checkpoint Inhibitors pembrolizumab Paclitaxel Cisplatin
article_metadata: PMC7876253
article_metadata: 33584678
article_metadata: Case Report: Therapeutic Response to Chemo-Immunotherapy in an Advanced Large Cell Lung Carcinoma Patient With Low Values of Multiple Predictive Biomarkers
article_metadata: 2021