article_metadata: Li Wang Wen Wen Mengyue Deng Yue Li Gan Sun Xiaodong Zhao Xuemei Tang Huawei Mao
article_metadata: 10.3389/fimmu.2021.674808
article_metadata: Front Immunol
article_metadata: 2021 Jun 23;12:674808.
article_metadata: nlrc4 autoinflammatory disease mild phenotype novel mutation urticaria
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/34248956/
article_metadata: CARD Signaling Adaptor Proteins / genetics Calcium-Binding Proteins / genetics Hereditary Autoinflammatory Diseases / genetics Urticaria / genetics
article_metadata: CARD Signaling Adaptor Proteins / genetics Calcium-Binding Proteins / genetics Hereditary Autoinflammatory Diseases / genetics Urticaria / genetics Case Reports Research Support, Non-U.S. Gov't Adult Arthralgia / genetics CARD Signaling Adaptor Proteins / metabolism Calcium-Binding Proteins / metabolism Caspase 1 / metabolism Child, Preschool Cryopyrin-Associated Periodic Syndromes / genetics Cytokines / metabolism Enterocolitis / genetics Female Genetic Diseases, Inborn Hereditary Autoinflammatory Diseases / diagnosis Humans Inflammasomes Inflammation / genetics Macrophage Activation Syndrome / genetics Male Molecular Structure Mutation CARD Signaling Adaptor Proteins Calcium-Binding Proteins Cytokines Inflammasomes NLRC4 protein, human Caspase 1
article_metadata: PMC8260849
article_metadata: 34248956
article_metadata: A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria
article_metadata: 2021