article_metadata: Sara Bruzzaniti Emilia Cirillo Rosaria Prencipe Giuliana Giardino Maria Teresa Lepore Federica Garziano Francesco Perna Claudio Procaccini Luigi Mascolo Cristina Pagano Valentina Fattorusso Enza Mozzillo Maurizio Bifulco Giuseppe Matarese Adriana Franzese Claudio Pignata Mario Galgani
article_metadata: 10.3389/fimmu.2020.01742
article_metadata: Front Immunol
article_metadata: 2020 Sep 18;11:1742.
article_metadata: cd4+ t cells mulibrey syndrome trim37 immune response immunological defects
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/33042106/
article_metadata: CD4-Positive T-Lymphocytes / immunology Mulibrey Nanism / genetics Mutation Tripartite Motif Proteins / genetics Ubiquitin-Protein Ligases / genetics
article_metadata: CD4-Positive T-Lymphocytes / immunology Mulibrey Nanism / genetics Mutation Tripartite Motif Proteins / genetics Ubiquitin-Protein Ligases / genetics Case Reports Research Support, Non-U.S. Gov't CD4-Positive T-Lymphocytes / metabolism CD8-Positive T-Lymphocytes / immunology CD8-Positive T-Lymphocytes / metabolism Cell Proliferation Cells, Cultured Child Cytokines / metabolism Genetic Predisposition to Disease Heredity Humans Immunologic Memory Lymphocyte Activation Male Mulibrey Nanism / diagnosis Mulibrey Nanism / immunology Mulibrey Nanism / metabolism Pedigree Phenotype Cytokines Tripartite Motif Proteins TRIM37 protein, human Ubiquitin-Protein Ligases
article_metadata: PMC7530177
article_metadata: 33042106
article_metadata: CD4+ T Cell Defects in a Mulibrey Patient With Specific TRIM37 Mutations
article_metadata: 2020