article_metadata: T Wakai T Kanda S Hirota A Ohashi Y Shirai K Hatakeyama
article_metadata: 10.1038/sj.bjc.6601819
article_metadata: Br J Cancer
article_metadata: 2004 Jun 1;90(11):2059-61.
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/15150562/
article_metadata: Antineoplastic Agents / pharmacology Gastrointestinal Neoplasms / drug therapy Gastrointestinal Neoplasms / genetics Proto-Oncogene Proteins c-kit / genetics
article_metadata: Antineoplastic Agents / pharmacology Gastrointestinal Neoplasms / drug therapy Gastrointestinal Neoplasms / genetics Proto-Oncogene Proteins c-kit / genetics Case Reports Benzamides DNA Mutational Analysis Drug Resistance, Neoplasm / genetics Gastrointestinal Neoplasms / pathology Humans Imatinib Mesylate Male Middle Aged Piperazines / pharmacology Pyrimidines / pharmacology Stromal Cells Antineoplastic Agents Benzamides Piperazines Pyrimidines Imatinib Mesylate Proto-Oncogene Proteins c-kit
article_metadata: PMC2409485
article_metadata: 15150562
article_metadata: Late resistance to imatinib therapy in a metastatic gastrointestinal stromal tumour is associated with a second KIT mutation
article_metadata: 2004