article_metadata: Chuanzhen Cao Zhichao Fu Yueping Liu Aiping Zhou Jianfei Wang Jianzhong Shou
article_metadata: 10.3389/fimmu.2021.684879
article_metadata: Front Immunol
article_metadata: 2021 Jun 10;12:684879.
article_metadata: bladder-sparing chemotherapy immunotherapy muscle-invasive bladder cancer next-generation sequencing
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/34177933/
article_metadata: Carcinoma, Transitional Cell / therapy Muscle Neoplasms / therapy Retinoblastoma Binding Proteins / genetics Ubiquitin-Protein Ligases / genetics Urinary Bladder Neoplasms / therapy
article_metadata: Carcinoma, Transitional Cell / therapy Muscle Neoplasms / therapy Retinoblastoma Binding Proteins / genetics Ubiquitin-Protein Ligases / genetics Urinary Bladder Neoplasms / therapy Case Reports Antibodies, Monoclonal, Humanized Carcinoma, Transitional Cell / genetics Carcinoma, Transitional Cell / pathology Chemoradiotherapy Humans Immunotherapy Male Middle Aged Muscle Neoplasms / secondary Mutation Neoadjuvant Therapy Remission Induction Treatment Outcome Urinary Bladder Neoplasms / genetics Urinary Bladder Neoplasms / pathology Antibodies, Monoclonal, Humanized RB1 protein, human Retinoblastoma Binding Proteins pembrolizumab Ubiquitin-Protein Ligases
article_metadata: PMC8222973
article_metadata: 34177933
article_metadata: A Muscle-Invasive Bladder Cancer Patient With High Tumor Mutational Burden and RB1 Mutation Achieved Bladder Preservation Following Chemotherapy Combined With Immunotherapy: A Case Report
article_metadata: 2021