article_metadata: Alevtina Gall Marita Bosticardo Stacey Ma Karin Chen Kayla Amini Francesca Pala Ottavia M Delmonte Tara Wenger Michael Bamshad John Sleasman Matthew Blessing Nicolai S C van Oers Luigi D Notarangelo M Teresa de la Morena
article_metadata: 10.3389/fimmu.2024.1438383
article_metadata: Front Immunol
article_metadata: 2024 Sep 18:15:1438383.
article_metadata: t cell lymphopenia tp63 ankyloblepharon-ectodermal defects-cleft lip/palate (aec) artificial thymic organoids cultured thymus tissue implantation (ctti) ectrodactyly-ectodermal dysplasia clefting (eec)
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39364398/
article_metadata: Lymphopenia / genetics Lymphopenia / immunology Organoids Thymus Gland / immunology Transcription Factors / genetics Tumor Suppressor Proteins / genetics
article_metadata: Lymphopenia / genetics Lymphopenia / immunology Organoids Thymus Gland / immunology Transcription Factors / genetics Tumor Suppressor Proteins / genetics Case Reports Cell Differentiation Female Humans Infant, Newborn Mutation T-Lymphocytes / immunology Transcription Factors TP63 protein, human Tumor Suppressor Proteins T-Lymphocytopenia
article_metadata: PMC11448704
article_metadata: 39364398
article_metadata: Case report: Artificial thymic organoids facilitate clinical decisions for a patient with a TP63 variant and severe persistent T cell lymphopenia
article_metadata: 2024