article_metadata: Xuelian Jin Zhigang Liu Yu Wu Jie Ji
article_metadata: 10.3389/fimmu.2024.1475974
article_metadata: Front Immunol
article_metadata: 2025 Jan 14:15:1475974.
article_metadata: all bcl-2 inhibitor (venetoclax) mll-af4 demethylation (azacitidine) histone deacetylase inhibitor (chidamide) leukemia relapsed/refractory targeted therapy
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/39877348/
article_metadata: Aminopyridines / therapeutic use Antineoplastic Combined Chemotherapy Protocols / therapeutic use Azacitidine / administration & dosage Azacitidine / therapeutic use Benzamides / therapeutic use Bridged Bicyclo Compounds, Heterocyclic / therapeutic use Myeloid-Lymphoid Leukemia Protein / genetics Oncogene Proteins, Fusion / genetics Sulfonamides / administration & dosage Sulfonamides / therapeutic use
article_metadata: Aminopyridines / therapeutic use Antineoplastic Combined Chemotherapy Protocols / therapeutic use Azacitidine / administration & dosage Azacitidine / therapeutic use Benzamides / therapeutic use Bridged Bicyclo Compounds, Heterocyclic / therapeutic use Myeloid-Lymphoid Leukemia Protein / genetics Oncogene Proteins, Fusion / genetics Sulfonamides / administration & dosage Sulfonamides / therapeutic use Case Reports Review Hematopoietic Stem Cell Transplantation Humans Male Middle Aged Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / therapy Treatment Outcome N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide Myeloid-Lymphoid Leukemia Protein Oncogene Proteins, Fusion Azacitidine Benzamides venetoclax Bridged Bicyclo Compounds, Heterocyclic Sulfonamides Aminopyridines MLL-AF4 fusion protein, human
article_metadata: PMC11772267
article_metadata: 39877348
article_metadata: Venetoclax in combination with chidamide and azacitidine for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia with the MLL-AF4 gene: a case report and literature review
article_metadata: 2025