article_metadata: Wanwan Cheng Ting Xu Lu Yang Naimeng Yan Jie Yang Shencun Fang
article_metadata: 10.1093/oncolo/oyae166
article_metadata: Oncologist
article_metadata: 2025 Jan 17;30(1):oyae166.
article_metadata: met rearrangement nsclc biomarker crizotinib sensitive
article_metadata: CC BY
article_metadata: https://pubmed.ncbi.nlm.nih.gov/38954846/
article_metadata: Crizotinib / pharmacology Crizotinib / therapeutic use Lung Neoplasms / drug therapy Lung Neoplasms / genetics Lung Neoplasms / pathology Proto-Oncogene Proteins c-met / genetics Proto-Oncogene Proteins c-met / metabolism
article_metadata: Crizotinib / pharmacology Crizotinib / therapeutic use Lung Neoplasms / drug therapy Lung Neoplasms / genetics Lung Neoplasms / pathology Proto-Oncogene Proteins c-met / genetics Proto-Oncogene Proteins c-met / metabolism Case Reports Carcinoma, Squamous Cell / drug therapy Carcinoma, Squamous Cell / genetics Carcinoma, Squamous Cell / pathology Humans Male Middle Aged Oncogene Proteins, Fusion / genetics Phosphorylation / drug effects Protein Kinase Inhibitors / pharmacology Protein Kinase Inhibitors / therapeutic use Vesicular Transport Proteins Crizotinib Proto-Oncogene Proteins c-met MET protein, human TFG protein, human Protein Kinase Inhibitors Oncogene Proteins, Fusion Vesicular Transport Proteins
article_metadata: PMC11783276
article_metadata: 38954846
article_metadata: Dramatic response to crizotinib through MET phosphorylation inhibition in rare TFG-MET fusion advanced squamous cell lung cancer
article_metadata: 2025