case_images: PMC11705995_01
case_images: (A) The photograph shows bilateral gestational gigantomastia R > L with skin changes. (B) The photograph shows the patient 1 month post bilateral simple mastectomies.
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case_images: f1
case_images: There was no associated palpable lymphadenopathy (Fig. 1A). She was counselled on delayed breast reconstruction, but being symptom-free was not interested and she was satisfied with her outcome (Fig. 1B).
case_images: Histological slides showing: (A) Fibroblastic proliferation with cleft like spaces within and adjacent to lobular sclerosing hyperplasia (x20). (B) Cleft-like spaces lined by benign flattened stromal myofibroblasts (x200).
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case_images: f2
case_images: The stroma was paucicellular with foci of cellular fascicular growth (Fig. 2).
case_images: Histological slides showing immunohistochemistry stain expression: (A) Myofibroblasts and endothelial cells showing immune expression for CD34 (x100). (B) CD31 immunostain highlights endothelial cells in blood vessels with no immunoexpression in the stromal myofibroblasts (x100). (C) Factor VIII immunostain of endothelial cells in the blood vessels with no immunoexpression in the stromal myofibroblasts (x100). (D) PR immunostain showing wild type staining in benign breast ducts with no immunoexpression in the stromal myofibroblasts (x100).
case_images: rjae835f3.jpg
case_images: PMC11705995_01_rjae835f3.jpg
case_images: f3
case_images: The glandular epithelium showed wild-type expression of both oestrogen and progesterone receptors (Fig. 3).