case_images: PMC8419549_01
case_images: The computed tomography chest showing multiple metastatic lesions in bilateral lung fields.
case_images: 10.1177_23247096211043397-fig1.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig1.jpg
case_images: fig1-23247096211043397
case_images: However, CT head showed no metastases (Figures 1 & 2).
case_images: The computed tomography abdomen and pelvis showing multiple hepatic metastases.
case_images: 10.1177_23247096211043397-fig2.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig2.jpg
case_images: fig2-23247096211043397
case_images: However, CT head showed no metastases (Figures 1 & 2).
case_images: Neoplastic cells containing round to slightly irregular nuclei with moderate amount of cytoplasm. Cells are existing in irregular interdigitating islands. There is no evidence of significant necrosis.
case_images: 10.1177_23247096211043397-fig3.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig3.jpg
case_images: fig3-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
case_images: Neoplastic cells with irregular nuclei and moderate amount of cytoplasm. The fibrous stroma containing scattered thin-walled ectatic vessels and well-developed collagen with fibroblast nuclei.
case_images: 10.1177_23247096211043397-fig4.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig4.jpg
case_images: fig4-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
case_images: Staining positive for synaptophysin.
case_images: 10.1177_23247096211043397-fig5.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig5.jpg
case_images: fig5-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
case_images: Staining positive for HepPar 1.
case_images: 10.1177_23247096211043397-fig6.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig6.jpg
case_images: fig6-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
case_images: Staining positive for cytokeratin 7.
case_images: 10.1177_23247096211043397-fig7.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig7.jpg
case_images: fig7-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).
case_images: Staining positive for alpha-fetoprotein.
case_images: 10.1177_23247096211043397-fig8.jpg
case_images: PMC8419549_01_10.1177_23247096211043397-fig8.jpg
case_images: fig8-23247096211043397
case_images: Taken together, the histological and immunocytochemical features appeared most consistent with a primary hepatocellular neoplasm, along with a strong neuroendocrine co-expression (Figures 3-8).