case_images: PMC10828076_01
case_images: (A) Endoscopy revealed a depressed type tumor with pale color (white arrows) and submucosal tumor-like enlarged folds (yellow arrow) on the greater curvature of the middle gastric body, suggesting the submucosal expansion of the former tumor to the gastric wall. (B) Barium swallow radiography confirmed markedly swollen folds of the gastric wall (arrows), suggesting the invasion to a deeper submucosal layer or muscle layer.
case_images: cmj-60-87-g001.jpg
case_images: PMC10828076_01_cmj-60-87-g001.jpg
case_images: F1
case_images: Endoscopy revealed a depressed type tumor with pale color and submucosal tumor (SMT)-like enlarged folds on the greater curvature of the middle gastric body (Fig. 1A). Additional barium swallow radiography confirmed swollen folds of the gastric wall (Fig. 1B).
case_images: Histopathological examination of the resected stomach (H&E). (A) The depressed lesion was diagnosed as intraepithelial moderately differentiated tubular adenocarcinoma and poorly differentiated adenocarcinoma. An arrow indicates the mucosal layer. (B) The submucosal tumor-like lesions showed multiple cystic dilatation of the heterotopic gastric glands extending into the submucosa (arrows), consistent with hypertrophic gastritis with gastritis cystica profunda without signs of malignancy.
case_images: cmj-60-87-g002.jpg
case_images: PMC10828076_01_cmj-60-87-g002.jpg
case_images: F2
case_images: The depressed lesion was diagnosed as intraepithelial moderately differentiated tubular adenocarcinoma and poorly differentiated adenocarcinoma without lymph node metastasis (Fig. 2A). The SMT-like lesions showed hypertrophic gastritis with gastritis cystica profunda (GCP) without signs of malignancy (Fig. 2B).