case_images: PMC10497364_01
case_images: Contrast-enhanced CT showing a sizeable (4.38 x 4.26 cm) well-circumscribed heterogeneous mass anteroinferior to the hyoid bone in axial (a), sagittal (b), and coronal (c) planes.
case_images: CRIOT2023-6640087.001.jpg
case_images: PMC10497364_01_CRIOT2023-6640087.001.jpg
case_images: fig1
case_images: Contrast-enhanced computerized tomography (CT) revealed a sizeable (4.38 x 4.26 cm) well-circumscribed mass anteroinferior to the hyoid bone, showing a moderate heterogeneous contrast enhancement (Figure 1).
case_images: (a) Papillary thyroid carcinoma arising in a thyroglossal duct cyst (left) exhibits classical papillary morphology with invasion of the cyst wall (indicated by black arrows). The cyst is lined by stratified squamous epithelium (indicated by red arrowheads), and normal thyroid follicles are present in the cyst wall (indicated by a black circle) (H&E stain, 40x magnification). (b) The carcinoma exhibits tall cell features in approximately 20% of the tumor (H&E stain, 200x magnification).
case_images: CRIOT2023-6640087.002.jpg
case_images: PMC10497364_01_CRIOT2023-6640087.002.jpg
case_images: fig2
case_images: Permanent histopathology revealed a BRAFV600E-positive classic PTC in a TDC (Figure 2(a)), exhibiting tall cell features in approximately 20% of the tumor cells (Figure 2(b)).
case_images: The presence of metastatic papillary carcinoma with tall cell features was observed in a lymph node at level VI (H&E stain, 100x magnification).
case_images: CRIOT2023-6640087.003.jpg
case_images: PMC10497364_01_CRIOT2023-6640087.003.jpg
case_images: fig3
case_images: Furthermore, three lymph nodes were infiltrated by PTC, none larger than 6 mm and without extranodal extension (Figure 3).