case_images: PMC5941754_01
case_images: Initial intraoral photograph (age: 4 months).
case_images: CRID2018-3048429.001.jpg
case_images: PMC5941754_01_CRID2018-3048429.001.jpg
case_images: fig1
case_images: Her parents reported, during the first months of life, the spontaneous formation of a pink oblong vesicle in the left internal part of the lower lip (Figure 1).
case_images: PMC5941754_02
case_images: Intraoral photograph (age: 6 months).
case_images: CRID2018-3048429.002.jpg
case_images: PMC5941754_02_CRID2018-3048429.002.jpg
case_images: fig2
case_images: After a month, the patient returned, and the lesion had a significant growth with a shape modification and appeared as a more regular bulla (Figure 2).
case_images: PMC5941754_03
case_images: Laser-assisted lesion excision (age: 6 months).
case_images: CRID2018-3048429.003.jpg
case_images: PMC5941754_03_CRID2018-3048429.003.jpg
case_images: fig3
case_images: The tip was directed at an angle of 10 to 15 , moving around the base of the lesion with a circular motion (Figure 3).
case_images: Intraoral photograph immediately after intervention.
case_images: CRID2018-3048429.004.jpg
case_images: PMC5941754_03_CRID2018-3048429.004.jpg
case_images: fig4
case_images: The diode laser provided a combination of clean cutting of the tissue and hemostasis (Figure 4).
case_images: PMC5941754_04
case_images: Healing (age: 6.5 months).
case_images: CRID2018-3048429.005.jpg
case_images: PMC5941754_04_CRID2018-3048429.005.jpg
case_images: fig5
case_images: After 2 weeks follow-up (Figure 5), the intraoral wound healed without complications and no signs of infection or mass recurrence were noted.
case_images: Follow-up (age: 10 months).
case_images: CRID2018-3048429.006.jpg
case_images: PMC5941754_04_CRID2018-3048429.006.jpg
case_images: fig6
case_images: After 4 months (Figure 6) follow-up, the lesion healed completely and the patient had a functionally and developmentally normal mucosa without lesion recurrence.
case_images: The lesion measured about 1 cm maximal length, displayed a polypoid fashion, and was covered by a smooth mucosal layer.
case_images: CRID2018-3048429.007.jpg
case_images: PMC5941754_04_CRID2018-3048429.007.jpg
case_images: fig7
case_images: Grossly, the lesion displayed a polypoid fashion and was covered by a smooth mucosal layer (Figure 7).
case_images: Histologic examination revealed a process deep seated within the submucosal connective tissue (HE, x2 magnification).
case_images: CRID2018-3048429.008.jpg
case_images: PMC5941754_04_CRID2018-3048429.008.jpg
case_images: fig8
case_images: Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).
case_images: The lesion consisted of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (HE, x10 magnification).
case_images: CRID2018-3048429.009.jpg
case_images: PMC5941754_04_CRID2018-3048429.009.jpg
case_images: fig9
case_images: Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).
case_images: Extracellular mucin resulted Alcian blue positive (Alcian-PAS, x20 magnification).
case_images: CRID2018-3048429.010.jpg
case_images: PMC5941754_04_CRID2018-3048429.010.jpg
case_images: fig10
case_images: Histologic examination revealed a process deep seated within the submucosal connective tissue (Figure 8), consisting of newly formed capillary vessels intermingled with a chronic, lymphohistiocytic inflammatory infiltrate and associated with deposition of extracellular mucin (Figure 9), the latter which resulted Alcian blue positive (Figure 10).