case_images: PMC10666958_01
case_images: PMC10666958_02
case_images: PMC10666958_03
case_images: PMC10666958_04
case_images: PMC10666958_05
case_images: ERGs (mixed rod-cone and cone-mediated) recorded in case 3 at baseline and 1 month after nanolaser 2RT treatment in the LE.
case_images: cop-2023-0014-0001-534579_F01.jpg
case_images: PMC10666958_05_cop-2023-0014-0001-534579_F01.jpg
case_images: F1
case_images: Representative mixed rod-cone ERGs and cone ERGs recorded at baseline and 1 month after 2RT in case 3 are shown in Figure 1.
case_images: PMC10666958_06
case_images: Plots of FDT sensitivity recorded in case 3 at baseline and at 1 year after nanolaser 2RT in the LE.
case_images: cop-2023-0014-0001-534579_F02.jpg
case_images: PMC10666958_06_cop-2023-0014-0001-534579_F02.jpg
case_images: F2
case_images: The perimetric FDT maps recorded in the same patient (case 3) at baseline and 1 year after 2 RT are shown in Figure 2.
case_images: Multifocal ERG results for the patients, showing response amplitude densities recorded at baseline and at 12-month post-treatment.
case_images: cop-2023-0014-0001-534579_F03.jpg
case_images: PMC10666958_06_cop-2023-0014-0001-534579_F03.jpg
case_images: F3
case_images: In Figure 3, plots of multifocal ERG response amplitude densities as a function of retinal eccentricity, recorded at baseline and after 12 month following treatment, are shown.
case_images: a Clinical findings of case 1 at baseline and after 2RT treatment (24 months RE-28 months LE). Drusenoid deposits tended to be more thickened at the level of the RPE, and RPE atrophic changes appeared to progress. The retinal thickness did not change significantly. b Clinical findings of case 2 at baseline and after 2RT treatment (24 months RE-21 months LE). Drusenoid deposits tended to be more thickened at the level of the RPE, whose atrophic changes appeared to progress. The retinal thickness did not change significantly. c Clinical findings of case 3 at baseline and after 2RT treatment (30 months both eyes). Drusenoid deposits tended to be more thickened at the level of the RPE, whose atrophic changes appeared to progress. The retinal thickness did not change significantly.
case_images: cop-2023-0014-0001-534579_F04.jpg
case_images: PMC10666958_06_cop-2023-0014-0001-534579_F04.jpg
case_images: F4
case_images: The retinal microstructure highlighted by OCT was compared before and 12 months after 2RT for both eyes in each case (Fig. 4a, c).