case_images: PMC9686401_01
case_images: Neuroimages of case 1. (A) Cranial magnetic resonance images revealed diffuse mild atrophy including the bilateral hippocampus. (B) N-isopropyl-p-[123I] iodoamphetamine single-photon emission computed tomography revealed hypoperfusion in the bilateral occipital and parietal lobes. (C) Cardiac [123I]-metaiodobenzylguanidine scintigraphy revealed heart-to-mediastinum ratios of 1.55 and 1.26 in the early and delayed phases, respectively.
case_images: fpsyt-13-1051067-g001.jpg
case_images: PMC9686401_01_fpsyt-13-1051067-g001.jpg
case_images: F1
case_images: Cranial magnetic resonance imaging (MRI) revealed diffuse very mild atrophy including the bilateral hippocampus (Figure 1). N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) single-photon emission computed tomography (SPECT) revealed hypoperfusion in the bilateral occipital and parietal lobes (Figure 1). Furthermore, cardiac 123I-metaiodobenzylguanidine scintigraphy revealed reduced myocardial uptake (heart-to-mediastinum ratio = early: 1.55; delayed: 1.26; Figure 1).
case_images: PMC9686401_02
case_images: The patient in case 2 showed us pictures of lint that she thought looked like insects, which is known as the "specimen sign" or "matchbox sign". (A,B) Picture of an object on her skin. (C) She pasted the object onto a paper and (D) found the object on the carpet.
case_images: fpsyt-13-1051067-g002.jpg
case_images: PMC9686401_02_fpsyt-13-1051067-g002.jpg
case_images: F2
case_images: I can't see insects when they crawl in my clothes," and "They crawled on the skin of my neck, trunk, and limbs. I felt tingling." She showed us pictures of lint on her limbs, claiming they were pictures of insects (Figure 2).
case_images: Neuroimages of case 2. (A) Cranial magnetic resonance revealed right dominant bilateral diffuse atrophy and right putamen chronic hemorrhage. (B) N-isopropyl-p-[123I] iodoamphetamine single-photon emission computed tomography revealed hypoperfusion in the right basal ganglia and the frontal, temporal, and parietal lobes. (C) Cardiac [123I]-metaiodobenzylguanidine scintigraphy revealed heart-to-mediastinum ratios of 1.91 and 1.32 in the early and delayed phases, respectively.
case_images: fpsyt-13-1051067-g003.jpg
case_images: PMC9686401_02_fpsyt-13-1051067-g003.jpg
case_images: F3
case_images: Cranial MRI revealed an old hemorrhagic lesion in the right putamen and right dominant bilateral diffuse atrophy with ischemic changes secondary to SAH (Figure 3). 123I-IMP SPECT revealed hypoperfusion in the right basal ganglia and the frontal, temporal, and parietal lobes (Figure 3). Furthermore, cardiac 123I-metaiodobenzylguanidine scintigraphy revealed reduced myocardial uptake (heart-to-mediastinum ratio = early: 1.91; delayed: 1.32; Figure 3).