case_images: PMC8044764_01
case_images: (A) Chest computed tomography (CT) scan. (B) Protein electrophoresis for gamma globulin levels (black) before treatment. (C) Serum immunofixation electrophoresis demonstrating monoclonal IgG kappa proteins. (D) Bone marrow cytology (red arrows: plasma cells, x400). (E) Protein electrophoresis for gamma globulin levels (black) after autologous hematopoietic stem cell transplantation (ASCT).
case_images: fonc-11-662169-g001.jpg
case_images: PMC8044764_01_fonc-11-662169-g001.jpg
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case_images: Chest computed tomography (CT) scan showed multiple compression fractures of the vertebral bodies (Figure 1A).The complete blood count showed normocytic anemia with a hemoglobin level of 101.0 g/L (130-175 g/L). Further serum protein electrophoresis revealed monoclonal spike 59.98 g/L (Figure 1B). Immunofixation electrophoresis (Figure 1C) showed immunoglobulin G 85g/L (8-15.5 g/L), immunoglobulin A 308 mg/L (836-2,900 mg/L), immunoglobulin M 250 mg/L (700-2,200 mg/L), kappa light chain 83.50 g/L and lambda light chain 0.84 g/L. Bone marrow cytology showed plasma cells made up 6.5% of the population (Figure 1D). His monoclonal spike was reduced by 75% and he showed clinical improvement (Figure 1E).