case_images: PMC11763016_01
case_images: (a and b) Glomerulus showing segmental fibrinoid necrosis and cellular crescent formation (Hematoxylin and Eosin stain) with concomitant segments of capillary wall thickening and subepithelial fuschinophilic deposits (bold black arrow in b), Masson trichrome stain), original magnifications X40. (c) Immunofluorescence microscopy depicting global fine granular (3+ intensity staining for IgG), original magnifications X40.
case_images: IJN-35-1-105-g1.jpg
case_images: PMC11763016_01_IJN-35-1-105-g1.jpg
case_images: F1
case_images: RIU/ml. Renal biopsy [Figure 1] suggested crescentic glomerulonephritis with IgG deposits.
case_images: PMC11763016_02
case_images: (a) Glomerulus showing circumferential fibro cellular crescent formation, Hematoxylin and Eosin stain, (b) concomitant segments of capillary wall thickening and subepithelial fuschinophilic deposits (bold black arrow) Masson trichrome stain, (c) Segments of structural capillary wall abnormalities with spike formation, Jones methenamine silver stain, (d) PLA2R immunohistochemistry shows faint non diagnostic staining of podocytes(interpreted to be negative), original magnifications X40. (e) Immunofluorescence microscopy depicting global fine granular (3+intensity staining for IgG), original magnifications X40. PLA2R: phospholipase A2 receptor.
case_images: IJN-35-1-105-g2.jpg
case_images: PMC11763016_02_IJN-35-1-105-g2.jpg
case_images: F2
case_images: RIU/ml. Renal biopsy suggested crescentic glomerulonephritis [Figure 2] with IgG deposits.