case_images: PMC3970922_01
case_images: (A) Sacral pyoderma gangrenosum after multiple debridements. (B) Huge abdominal and left thigh wound defect with typical violaceous borders post-debridement.
case_images: ccid-7-105Fig1.jpg
case_images: PMC3970922_01_ccid-7-105Fig1.jpg
case_images: f1-ccid-7-105
case_images: After the third debridement, the abdominal ulcer had increased to a size of 32 cm x 11 cm, and the two sacral ulcers became a huge sacral defect extending into the perianal region (Figure 1A and B).
case_images: Histology of incisional biopsy of abdominal ulcer. (A) Extensive skin ulceration is shown (H&E stain; original magnification x10). (B) Higher-powered view of ulcer being covered by inflamed crust and infiltrated by a heavy collection of acute inflammatory cells (neutrophils) (H&E stain; x20).. Abbreviation: H&E, hematoxylin and eosin.
case_images: ccid-7-105Fig2.jpg
case_images: PMC3970922_01_ccid-7-105Fig2.jpg
case_images: f2-ccid-7-105
case_images: Repeated histological sections of sacral and abdominal tissues revealed neutrophilic infiltrates extending into deep dermis and no evidence of malignancy (Figure 2A and B).
case_images: After treatment with immunosuppressive medications, appearance of sacral (A) and abdominal and left thigh (B) pyoderma gangrenosum.
case_images: ccid-7-105Fig3.jpg
case_images: PMC3970922_01_ccid-7-105Fig3.jpg
case_images: f3-ccid-7-105
case_images: Four months after admission, the patient underwent successful split skin grafts and primary closure to her abdominal and sacral ulcers while on immunosuppressive therapy (Figure 3A and B).