case_images: PMC9906041_01
case_images: Emergency esophagogastroduodenoscopy (EGD). a EGD revealed gastric ulcer in the lesser curvature of the gastric angle. b Spurting bleeding occurred during observation, and hemostasis was attempted. c PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to suppression of the bleeding volume. d Hemostasis was subsequently achieved with an endoscopic hemoclip. e EGD revealed oozing bleeding from a Dieulafoy's lesion in the greater curvature of the gastric antrum. f Hemostasis treatment was attempted using an endoscopic hemoclip, but the bleeding persisted. g Thus, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume. h Hemostasis was subsequently achieved with an additional endoscopic hemoclip.
case_images: crg-2022-0017-0001-528896_f1.jpg
case_images: PMC9906041_02_crg-2022-0017-0001-528896_f1.jpg
case_images: F1
case_images: Emergency EGD revealed oozing bleeding from a Dieulafoy's lesion in the greater curvature of the gastric antrum (Fig. 1e). Hemostasis was attempted using an endoscopic hemoclip, but the bleeding persisted (Fig. 1f). Thus, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume (Fig. 1g). Hemostasis was subsequently achieved with an additional endoscopic hemoclip (Fig. 1h).
case_images: PMC9906041_02
case_images: Emergency esophagogastroduodenoscopy (EGD). a EGD revealed gastric ulcer in the lesser curvature of the gastric angle. b Spurting bleeding occurred during observation, and hemostasis was attempted. c PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to suppression of the bleeding volume. d Hemostasis was subsequently achieved with an endoscopic hemoclip. e EGD revealed oozing bleeding from a Dieulafoy's lesion in the greater curvature of the gastric antrum. f Hemostasis treatment was attempted using an endoscopic hemoclip, but the bleeding persisted. g Thus, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume. h Hemostasis was subsequently achieved with an additional endoscopic hemoclip.
case_images: crg-2022-0017-0001-528896_f1.jpg
case_images: PMC9906041_02_crg-2022-0017-0001-528896_f1.jpg
case_images: F1
case_images: Emergency EGD revealed oozing bleeding from a Dieulafoy's lesion in the greater curvature of the gastric antrum (Fig. 1e). Hemostasis was attempted using an endoscopic hemoclip, but the bleeding persisted (Fig. 1f). Thus, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume (Fig. 1g). Hemostasis was subsequently achieved with an additional endoscopic hemoclip (Fig. 1h).
case_images: PMC9906041_03
case_images: Emergency esophagogastroduodenoscopy (EGD). a EGD revealed spurting bleeding from gastric varices. b Hemostasis treatment was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding. c Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, (d) which led to complete hemostasis. e EGD revealed duodenal ulcer and oozing bleeding from a visible vessel in the inferior aspect of the duodenal bulb. f Hemostasis treatment was attempted using PuraStat (1 mL) through a dedicated catheter, followed by an endoscopic hemoclip.  g As the bleeding persisted, PuraStat (2 mL) was applied to the bleeding site, (h) and complete hemostasis was achieved.
case_images: crg-2022-0017-0001-528896_f2.jpg
case_images: PMC9906041_04_crg-2022-0017-0001-528896_f2.jpg
case_images: F2
case_images: Emergency EGD revealed a duodenal ulcer as well as oozing bleeding from a visible vessel in the inferior aspect of the duodenal bulb (Fig. 2e). Hemostasis was attempted by applying PuraStat (1 mL) through a dedicated catheter (Fig. 2f), followed by an endoscopic hemoclip, but the bleeding persisted (Fig. 2g). Thus, PuraStat (2 mL) was again applied to the bleeding site, and complete hemostasis was achieved (Fig. 2h).
case_images: PMC9906041_04
case_images: Emergency esophagogastroduodenoscopy (EGD). a EGD revealed spurting bleeding from gastric varices. b Hemostasis treatment was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding. c Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, (d) which led to complete hemostasis. e EGD revealed duodenal ulcer and oozing bleeding from a visible vessel in the inferior aspect of the duodenal bulb. f Hemostasis treatment was attempted using PuraStat (1 mL) through a dedicated catheter, followed by an endoscopic hemoclip.  g As the bleeding persisted, PuraStat (2 mL) was applied to the bleeding site, (h) and complete hemostasis was achieved.
case_images: crg-2022-0017-0001-528896_f2.jpg
case_images: PMC9906041_04_crg-2022-0017-0001-528896_f2.jpg
case_images: F2
case_images: Emergency EGD revealed a duodenal ulcer as well as oozing bleeding from a visible vessel in the inferior aspect of the duodenal bulb (Fig. 2e). Hemostasis was attempted by applying PuraStat (1 mL) through a dedicated catheter (Fig. 2f), followed by an endoscopic hemoclip, but the bleeding persisted (Fig. 2g). Thus, PuraStat (2 mL) was again applied to the bleeding site, and complete hemostasis was achieved (Fig. 2h).
case_images: PMC9906041_05
case_images: Emergency esophagogastroduodenoscopy (EGD) and colonoscopy (CS). a EGD revealed oozing bleeding from a small intestinal ulcer on the anal side of the anastomosis. b PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume, (c) but the oozing bleeding continued from a visible vessel. d Hemostasis was subsequently achieved using an endoscopic hemoclip. e, f CS revealed multiple rectal ulcers and spurting bleeding from a visible vessel in a rectal ulcer. g Hemostasis treatment was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding. h Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, and complete hemostasis was achieved.
case_images: crg-2022-0017-0001-528896_f3.jpg
case_images: PMC9906041_06_crg-2022-0017-0001-528896_f3.jpg
case_images: F3
case_images: Emergency colonoscopy revealed multiple rectal ulcers and spurting bleeding from a visible vessel in a rectal ulcer (Fig. 3e, f). Hemostasis was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding (Fig. 3g). Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, and complete hemostasis was achieved (Fig. 3h).
case_images: PMC9906041_06
case_images: Emergency esophagogastroduodenoscopy (EGD) and colonoscopy (CS). a EGD revealed oozing bleeding from a small intestinal ulcer on the anal side of the anastomosis. b PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, which led to a reduction in bleeding volume, (c) but the oozing bleeding continued from a visible vessel. d Hemostasis was subsequently achieved using an endoscopic hemoclip. e, f CS revealed multiple rectal ulcers and spurting bleeding from a visible vessel in a rectal ulcer. g Hemostasis treatment was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding. h Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, and complete hemostasis was achieved.
case_images: crg-2022-0017-0001-528896_f3.jpg
case_images: PMC9906041_06_crg-2022-0017-0001-528896_f3.jpg
case_images: F3
case_images: Emergency colonoscopy revealed multiple rectal ulcers and spurting bleeding from a visible vessel in a rectal ulcer (Fig. 3e, f). Hemostasis was attempted using an endoscopic hemoclip, which led to immediate reduction of bleeding (Fig. 3g). Subsequently, PuraStat (3 mL) was applied to the bleeding site through a dedicated catheter, and complete hemostasis was achieved (Fig. 3h).