case_images: PMC10602704_01
case_images: Patient 1 had many small-to-large erosions on her face (a) and trunk (c, d), without any mucosal lesions (b). Histopathological examination shows acantholysis above the stratum basalis (e). Direct immunofluorescence showed reticular intracellular C3 (f) and IgG (g) levels.
case_images: CRIDM2023-1218388.001.jpg
case_images: PMC10602704_01_CRIDM2023-1218388.001.jpg
case_images: fig1
case_images: A 53-year-old woman was hospitalized for complaints of skin erosion that developed rapidly within 1 month (Figure 1).
case_images: PMC10602704_02
case_images: Patient 2 had scaling and oozing erosions on her face (a), trunk (b, c), and legs (d). Histopathological examination showed intraepidermal bullae formation (e). DIF showed net-like intracellular C3 (f) and IgG (g) levels.
case_images: CRIDM2023-1218388.002.jpg
case_images: PMC10602704_02_CRIDM2023-1218388.002.jpg
case_images: fig2
case_images: All symptoms started 2 months after her second dose of mRNA-1273 vaccine (Moderna, USA), with erosion and crusting on her neck and around the injection site, which spread to other places on her body (Figure 2).