case_images: PMC9108170_01
case_images: (A) Computed Tomography Scan before liver transplantation, November 2020. (B) Gross appearance of the tumor in explanted liver. (C) Cross-section of the tumor in explanted liver. (D) Histopathological features: Eosin-haematoxylin dye. Well-defined nests composed of short fascicles of bland looking spindle cells surrounded by desmoplastic stroma and areas of ossification, neocholangioli inside desmoplastic stroma are visible. (E) Histopathological features: nuclear and cytoplasmic immunohistochemical reaction with beta-katenin. (F) Magnetic Resonance Imaging 8-months after liver transplantation, July 2021.
case_images: fsurg-09-875782-g0001.jpg
case_images: PMC9108170_01_fsurg-09-875782-g0001.jpg
case_images: F1
case_images: In August 2020, a control Computed Tomography Scan revealed tumor volume growth occupying the right liver along with segment IV and segment I with the obstruction of intrahepatic inferior vena cava (Figure 1A). Histopathological examination presented a well-circumcised tan-white tumor of a maximum size of 26 cm and another 6 mm infracapsular tumor (Figures 1B,C). These nests were composed of short fascicles of bland looking spindle cells and inside the desmoplastic stroma neocholangioli were observed (Figure 1D). A characteristic feature of this tumor is the nuclear and cytoplasmic immunohistochemical reaction with beta-katenin (Figure 1E), which corresponds with previously reported histopathological characteristics of CNSET. Multiple diagnostic imaging carried out throughout the year showed no signs of recurrence (Figure 1F).