case_images: PMC10809415_01
case_images: Timeline of the patient's history of present illness.
case_images: fmed-10-1337303-g001.jpg
case_images: PMC10809415_01_fmed-10-1337303-g001.jpg
case_images: fig1
case_images: The timeline of history for the present illness was showcased in Figure 1.
case_images: (A) Chest tomography (CT) displayed a small hyperdense nodule (red circles) in the left principal bronchus, and (B) mild intensification was detected in the enhanced CT image. (C) Bronchoscopy visualized a smooth-surfaced neoplasm with airway obstruction in the left principal bronchus, and (D) it was excised with electrotomy and (E) removed successfully. (F) HE stain showed chronic active inflammation with histiocyte aggregation.
case_images: fmed-10-1337303-g002.jpg
case_images: PMC10809415_01_fmed-10-1337303-g002.jpg
case_images: fig2
case_images: Importantly, chest tomography (CT) displayed a small hyperdense nodule of approximately 5 mm x 6 mm in the left principal bronchus with mild intensification in the enhanced images (Figures 2A,B). By endotracheal endoscopy, a smooth-surfaced neoplasm with airway obstruction was visualized in the left principal bronchus (Figure 2C). Subsequently, the neoplasm was successfully removed with electrotomy (Figures 2D,E), and pathological biopsy with metagenomic next-generation sequencing (mNGS) was then carried out for precise diagnosis. The hematoxylin-eosin (HE) staining showed chronic active inflammation, evidenced by granulation tissue hyperplasia, inflammatory necrosis, and exudation, as well as histiocyte aggregation with a tendency of granuloma formation (Figure 2F). mNGS was conducted by Beijing Genomics Institute (BGI), Shenzhen.