case_images: PMC2627815_01
case_images: Preoperative photograph of patient 1.
case_images: 1757-1626-2-15-1.jpg
case_images: PMC2627815_01_1757-1626-2-15-1.jpg
case_images: F1
case_images: This patient is a 48 year old female who was admitted with a large fungating right breast mass which measured 22 x 20 cm and elevated 12 cm above the skin surface (Figure 1).
case_images: Postoperative photograph of patient 1.
case_images: 1757-1626-2-15-2.jpg
case_images: PMC2627815_01_1757-1626-2-15-2.jpg
case_images: F2
case_images: The skin flaps were viable, not grossly involved with tumor, and were able to be closed primarily (Figure 2).
case_images: Photomicrograph of carcinosarcoma (hematoxylin-eosin stain).
case_images: 1757-1626-2-15-3.jpg
case_images: PMC2627815_02_1757-1626-2-15-3.jpg
case_images: F3
case_images: The final pathology revealed the left simple mastectomy containing a 2.7 cm carcinosarcoma characterized by a grade 3 epithelial component with an associated, but separate, high grade mesenchymal component (Figures 3 &4).
case_images: Photomicrograph of carcinosarcoma (cytokeratin stain).
case_images: 1757-1626-2-15-4.jpg
case_images: PMC2627815_02_1757-1626-2-15-4.jpg
case_images: F4
case_images: The final pathology revealed the left simple mastectomy containing a 2.7 cm carcinosarcoma characterized by a grade 3 epithelial component with an associated, but separate, high grade mesenchymal component (Figures 3 &4).
case_images: Epidermal Growth Factor Receptor protein expression is analyzed by immunohistochemistry, staining positive.
case_images: 1757-1626-2-15-5.jpg
case_images: PMC2627815_02_1757-1626-2-15-5.jpg
case_images: F5
case_images: Ki-67 expression was 60%, with expression of the HER-1/EGFR receptor with a 50% strong staining intensity (Figure 5).
case_images: PMC2627815_02
case_images: Photomicrograph of carcinosarcoma (hematoxylin-eosin stain).
case_images: 1757-1626-2-15-3.jpg
case_images: PMC2627815_02_1757-1626-2-15-3.jpg
case_images: F3
case_images: The final pathology revealed the left simple mastectomy containing a 2.7 cm carcinosarcoma characterized by a grade 3 epithelial component with an associated, but separate, high grade mesenchymal component (Figures 3 &4).
case_images: Photomicrograph of carcinosarcoma (cytokeratin stain).
case_images: 1757-1626-2-15-4.jpg
case_images: PMC2627815_02_1757-1626-2-15-4.jpg
case_images: F4
case_images: The final pathology revealed the left simple mastectomy containing a 2.7 cm carcinosarcoma characterized by a grade 3 epithelial component with an associated, but separate, high grade mesenchymal component (Figures 3 &4).
case_images: Epidermal Growth Factor Receptor protein expression is analyzed by immunohistochemistry, staining positive.
case_images: 1757-1626-2-15-5.jpg
case_images: PMC2627815_02_1757-1626-2-15-5.jpg
case_images: F5
case_images: Ki-67 expression was 60%, with expression of the HER-1/EGFR receptor with a 50% strong staining intensity (Figure 5).