case_images: PMC10619999_01
case_images: Preoperative findings of right breast tumour.
case_images: cro-2023-0016-0001-533441_F01.jpg
case_images: PMC10619999_01_cro-2023-0016-0001-533441_F01.jpg
case_images: F1
case_images: Reassessment in April 2022 revealed that her tumour had grown in size with inflammation of overlying skin (Fig. 1).
case_images: Intraoperative image of right modified radical mastectomy.
case_images: cro-2023-0016-0001-533441_F02.jpg
case_images: PMC10619999_01_cro-2023-0016-0001-533441_F02.jpg
case_images: F2
case_images: Since the tumour was unresponsive to chemotherapy, she underwent a right modified radical mastectomy with insertion of expander on April 24, 2022 (Fig. 2).
case_images: Anterior aspect of the operative specimen.
case_images: cro-2023-0016-0001-533441_F03.jpg
case_images: PMC10619999_01_cro-2023-0016-0001-533441_F03.jpg
case_images: F3
case_images: Her post-operative histopathology came out to be grade 3 invasive ductal carcinoma (Fig. 3-5).
case_images: Posterior aspect of the operative specimen.
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case_images: PMC10619999_01_cro-2023-0016-0001-533441_F04.jpg
case_images: F4
case_images: Her post-operative histopathology came out to be grade 3 invasive ductal carcinoma (Fig. 3-5).
case_images: Gross sections of the excised tumour.
case_images: cro-2023-0016-0001-533441_F05.jpg
case_images: PMC10619999_01_cro-2023-0016-0001-533441_F05.jpg
case_images: F5
case_images: Her post-operative histopathology came out to be grade 3 invasive ductal carcinoma (Fig. 3-5).
case_images: a Cystic area of the invasive tumour. b Low magnification of invasive epithelial component with metaplastic area. c Higher magnification of the area. d Higher magnification of the pleomorphic and atypical spindled cells with frequent mitotic figures. e Epithelial component of the invasive carcinoma highlighted by immunohistochemistry for AE1/AE3. f Spindle cell component highlighted by immunohistochemistry for SMA, confirming smooth muscle differentiation in the metaplastic tumour.
case_images: cro-2023-0016-0001-533441_F06.jpg
case_images: PMC10619999_01_cro-2023-0016-0001-533441_F06.jpg
case_images: F6
case_images: The features were those of a high-grade invasive ductal carcinoma with sarcomatoid areas and were in accordance with a metaplastic carcinoma (Fig. 6.)