case_images: PMC10914250_01
case_images: (A) The colonoscopy shows a mass blocked the lumen of the descending colon and the endoscope could not pass; (B) The haematoxylin-eosin staining of the biopsy shows adenocarcinoma (red arrow); (C, D) The contrast-enhanced abdominal computed tomography shows the colon wall thickening and the maximum cross-section of the mass is 4.4x7.0 mm (red arrow).
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case_images: An 80-year-old Asian man with haematochezia for 10 days was admitted to our hospital in Nov. 2018 and diagnosed with advanced colon cancer, protruded type, clinical stage T2N0M0 ( Figure 1 ). Colonoscopy revealed a mass in the descending colon that blocked the lumen, and blocked passage of the endoscope ( Figure 1A ). Histopathological examination (H&E staining) showed deeply stained irregular nuclei with necrotizing tumour cells and revealed adenocarcinoma ( Figure 1B ). Contrast-enhanced abdominal computed tomography showed a thickening confined to the descending colon wall and no metastasis to the lymph nodes or abdominal organs ( Figures 1C, D ). Figures 2A, B ) and then placing a stent using the colonoscope ( Figure 2C ). From April 2019 to February 2021, the patient underwent a colonoscopy six times for the tumour in our hospital, including polyp resection, electro-coagulation and electro-section, and APC ( Supplementary Figure 1 ).
case_images: (A) The endoscopic resection and argon plasma coagulation of the tumour; (B) The excised tumour tissue; (C) The stent placed in the lumen.
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case_images: Figures 2A, B ) and then placing a stent using the colonoscope ( Figure 2C ). From April 2019 to February 2021, the patient underwent a colonoscopy six times for the tumour in our hospital, including polyp resection, electro-coagulation and electro-section, and APC ( Supplementary Figure 1 ).
case_images: The size of the tumour in the colon has gradually shrunk over three years from 2019 to 2021 after endoscopic therapy.
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case_images: The tumour size in the colon gradually decreased and no other complications developed ( Figure 3 ).
case_images: Scars are seen at the original tumour site in three (A) and four (B) years after the original diagnosis in 2018. (red arrow).
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case_images: Surprisingly, a regular examination with colonoscopy in July 2021 showed that only postoperative scars were seen at the original tumour site, and no tumour proliferation was found ( Figure 4A ). One year later, in May 2022, the patient underwent colonoscopy and still showed no colon cancer recurrence ( Figure 4B ).