case_images: PMC5646290_01
case_images: Pigmented pleomorphic tumor cells in Case 1 (HEX 200).
case_images: CRIPA2017-1807879.001.jpg
case_images: PMC5646290_01_CRIPA2017-1807879.001.jpg
case_images: fig1
case_images: On histological examination pleomorphic tumor cells were arranged in syncytial pattern (Figure 1).
case_images: Presence of diffuse HMB45 expression (DABX 200).
case_images: CRIPA2017-1807879.002.jpg
case_images: PMC5646290_01_CRIPA2017-1807879.002.jpg
case_images: fig2
case_images: Tumor cells showed diffuse and strong expression of HMB45 (Figure 2), Melan A, and S-100 protein but were negative for Cytokeratin, CD56, Chromogranin, Synaptophysin.
case_images: PMC5646290_02
case_images: In T1-contrasted axial series, extraspinal extension of the tumor from the spinal canal through the neural foramen is seen.
case_images: CRIPA2017-1807879.003.jpg
case_images: PMC5646290_02_CRIPA2017-1807879.003.jpg
case_images: fig3
case_images: Magnetic resonance imaging (MRI) of lumbar spine revealed intradural extramedullary lesion measuring 6.1 x 2.0 cm at L1-2 level near the right kidney which was hypointense on T1- and hyperintense on T2-weighted sequences (Figures 3 and 4).
case_images: In T1-contrasted coronal series, dumbbell shape extraspinal extension of tumor is monitored.
case_images: CRIPA2017-1807879.004.jpg
case_images: PMC5646290_02_CRIPA2017-1807879.004.jpg
case_images: fig4
case_images: Magnetic resonance imaging (MRI) of lumbar spine revealed intradural extramedullary lesion measuring 6.1 x 2.0 cm at L1-2 level near the right kidney which was hypointense on T1- and hyperintense on T2-weighted sequences (Figures 3 and 4).
case_images: Panoramic appearance of tumor with infiltrative border (HEX 20).
case_images: CRIPA2017-1807879.005.jpg
case_images: PMC5646290_02_CRIPA2017-1807879.005.jpg
case_images: fig5
case_images: Histopathology revealed spindle cell tumor arranged in lobular pattern with infiltrative border (Figure 5).
case_images: Tumor of Case 2 is composed of mostly spindle cells (HEX 200).
case_images: CRIPA2017-1807879.006.jpg
case_images: PMC5646290_02_CRIPA2017-1807879.006.jpg
case_images: fig6
case_images: Tumor cells had distinctive nucleoli and melanin pigments in cytoplasm (Figure 6).
case_images: Presence of diffuse S-100 protein expression (DABX 200).
case_images: CRIPA2017-1807879.007.jpg
case_images: PMC5646290_02_CRIPA2017-1807879.007.jpg
case_images: fig7
case_images: Immunohistochemical staining for HMB45, Melan A, Vimentin, S-100 protein (Figure 7), Cytokeratin, EMA, Actin, Desmin, and Ki 67 was performed.