case_images: PMC7235934_01
case_images: Colonoscopic findings.. (a) A 50-mm submucosal tumor-like mass was found in the hepatic flexure of the colon.. (b) Superficial biopsy and boring biopsy were performed
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case_images: PMC7235934_01_gr1.jpg
case_images: fig0005
case_images: On colonoscopy, a 50-mm submucosal tumor-like mass was found in the hepatic flexure of the colon (Fig. 1).
case_images: Contrast-enhanced computed tomography findings.. (a) The tumor occupied the transverse colon.. (b) Several regional lymph nodes were swollen.
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case_images: PMC7235934_01_gr2.jpg
case_images: fig0010
case_images: Contrast-enhanced computed tomography (CT) revealed a colonic tumor and swelling regional lymph node in the transverse colon (Fig. 2).
case_images: Microscopic pathological findings.. (a) At a low-power field, the tumor was found to originate from the muscle layer.. (b) At a high-power field, the spindle-shaped cells with weak eosinophilic endoplasmic spores proliferated with fibroblasts.. (c) Immunostaining revealed that the tumor cells were positive for S-100 protein.
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case_images: PMC7235934_01_gr3.jpg
case_images: fig0015
case_images: Pathologically, the tumor originated from the muscularis propria layer (Fig. 3a) and spindle cells with weak eosinophilic endoplasmic spores proliferated along with fibroblasts (Fig. 3b). Immunohistochemical staining revealed that the tumor was positive for S100 protein (Fig. 3c) but negative for CD34, c-kit, and desmin.