case_images: PMC11822436_01
case_images: Example of ICE score items, multiple-choice visual naming items and commands written in patient's native language (Simplified Chinese). The first column depicts the flashcards of the orientation questions and the instruction to write a sentence. The middle column depicts flashcard examples for visual naming with multiple-choice options. The last column depicts flashcards with command instructions. ICE, immune effector cell-associated encephalopathy.
case_images: bmjno-7-1-g001.jpg
case_images: PMC11822436_01_bmjno-7-1-g001.jpg
case_images: F1
case_images: The ICE score was modified so that orientation questions, simple commands and instructions for serial 10s and handwriting were provided in a written format in simplified Chinese on flashcards (figure 1).
case_images: PMC11822436_02
case_images: PMC11822436_03
case_images: PMC11822436_04
case_images: Examples of ICE scores of case 5 at baseline and during onset of ICANS. Baseline handwriting on day+0 (13 November 2023) and day+1 (14 November 2023) is depicted in the first three rows. Change in handwriting during the evolution of ICANS on day+4 (17 November 2023) is depicted. Handwriting is at baseline at 07:30 hours, spelling errors become evident at 12:50 hours and writing is severely dysgraphic at 14:00 hours, 16:21 hours and 18:28 hours. ICANS, immune effector cell-associated neurotoxicity syndrome; ICE, immune effector cell-associated encephalopathy.
case_images: bmjno-7-1-g003.jpg
case_images: PMC11822436_04_bmjno-7-1-g003.jpg
case_images: F3
case_images: An hour later, their ICE score dropped to 6/10 with points lost for orientation to year and month, serial 10s and sentence writing (figure 3).