case_images: PMC11324492_01
case_images: The CT demonstrates bone lesions located in the T11 vertebral body. (A) sagittal image. (B) coronal image. (C) axial image.
case_images: fonc-14-1417380-g001.jpg
case_images: PMC11324492_01_fonc-14-1417380-g001.jpg
case_images: f1
case_images: T11 vertebral body ( Figure 1 ). The 18F-FDG examination performed high-density nodular shadow in the 11th thoracic vertebra and right accessory bone.
case_images: (A) The initial 18F-FDG co-registered imaging depicts bone destruction in the 11th thoracic vertebra. An occurrence of soft tissue shadows and an increase in metabolism are also observed. (B) After two cycles of DKRd treatment, the 18F-FDG displays bone destruction shadows in the 11th thoracic vertebra, with no significant signs of hypermetabolism, the metabolic shadow is disappearance.
case_images: fonc-14-1417380-g002.jpg
case_images: PMC11324492_01_fonc-14-1417380-g002.jpg
case_images: f2
case_images: Increased metabolic activity indicated potential malignant lesions ( Figure 2 ). The 18F-FDG reexamination showed signs of bone lesions in the 11th thoracic vertebra without significant hypermetabolism, and the contrast agent hypermetabolism shadow disappeared ( Figure 2 ).
case_images: The pathologic immunohistochemistry of the 11th thoracic vertebra lesions is consistent with plasma cell neoplasms.
case_images: fonc-14-1417380-g003.jpg
case_images: PMC11324492_01_fonc-14-1417380-g003.jpg
case_images: f3
case_images: These findings are consistent with a diagnosis of plasma cell tumors ( Figure 3 ).