case_images: PMC5417814_01
case_images: Erythematopurpuric and crusted papules on the torso
case_images: 0103-0582-rpp-35-01-00115-gf1.jpg
case_images: PMC5417814_01_0103-0582-rpp-35-01-00115-gf1.jpg
case_images: f4
case_images: Her physical examination was within normal limits and dermatologic examination revealed tiny erythematopurpuric papules, some of which were crusted, scattered over the torso (Fig. 1).
case_images: Dense infiltrate of neoplastic cells in papillary dermis (straight arrows) with sparse epidermal infiltration (arrowheads) accompanied by extravasated erythrocytes (hematoxylin and eosin; original magnification, X400)
case_images: 0103-0582-rpp-35-01-00115-gf2.jpg
case_images: PMC5417814_01_0103-0582-rpp-35-01-00115-gf2.jpg
case_images: f5
case_images: The skin biopsy revealed a dense infiltrate of neoplastic cells in papillary dermis with sparse epidermal infiltration (Fig. 2).
case_images: (A) Focal immunohistochemical staining with CD1a in Langerhans cells (arrows) (immunoperoxidase; original magnification, X400). (B) Diffuse and dense positive staining with S100 protein in the Langerhans cells (arrows) (immunoperoxidase; original magnification, X400).
case_images: 0103-0582-rpp-35-01-00115-gf3.jpg
case_images: PMC5417814_01_0103-0582-rpp-35-01-00115-gf3.jpg
case_images: f6
case_images: In an immunhistochemical analysis, the neoplastic cells were positive for S100 and CD1a and negative for mast cell tryptase, CD117, and myeloperoxidase (Fig. 3).