case_images: PMC11004339_01
case_images: PMC11004339_02
case_images: Manifestations (A, B) in the PASH image showed changes in the double milk molybdenum target, which showed an oval isondense mass. (C, D) show ultrasound changes in both breasts, manifested as hypoechoic nodules with clear boundaries and cystic changes.
case_images: fonc-14-1359886-g001.jpg
case_images: PMC11004339_02_fonc-14-1359886-g001.jpg
case_images: f1
case_images: The shape was regular, the boundary was clear, and the echo was uniform ( Figures 1C, D ).
case_images: Bilateral mammary gland enlargement in patient (A) before surgery; (B) gross manifestations of tumor resection.
case_images: fonc-14-1359886-g002.jpg
case_images: PMC11004339_02_fonc-14-1359886-g002.jpg
case_images: f2
case_images: The sections were gray and grayish brown, the internodules showed edema or mucous changes, and multiple sac-like structures of different sizes could be seen without bleeding or necrosis ( Figure 2 ).
case_images: (A) At low power, a dense collagen matrix around and within the lobules was observed, with slit-like spaces (HE, 40X); (B) there were many fissure-like spaces in the dense collagenous breast interstitium, in which benign spindle cells were arranged without cytological atypia (HE, 200X); (C) epidermal hyperplasia of breast skin with hyperkeratosis, granulosa thickening and acanthosis edema; (D) focal points showed multiple intraductal common type (UDH) and papillary hyperplasia areas (HE, 40X); (E) a local enlarged UDH of the breast (HE, 200X); (F) ductal epithelial papillary hyperplasia of the breast (HE, 200X); (G) fusiform cells between fissures did not express the vasogenic marker CD31 (200X); (H) the expression of CD34 in fusiform cells between fissures was diffusively strong (200X); (I) PR was not expressed in fusiform cells of the interface (200X).
case_images: fonc-14-1359886-g003.jpg
case_images: PMC11004339_02_fonc-14-1359886-g003.jpg
case_images: f3
case_images: Epidermal hyperplasia of breast skin with hyperkeratosis, granulosa thickening with acanthosis, superficial dermis and perivascular lymphocyte infiltration were observed ( Figures 3A-F ). The fusiform cells of the lacunar lining were negative ( Figures 3G-I ).