case_images: PMC5949168_01
case_images: Coronal MRI T1 sequence with gadolinium. Intra- and suprasellar tumor with extension to the floor of third ventricle, after first surgery.
case_images: CRIE2018-5027859.001.jpg
case_images: PMC5949168_01_CRIE2018-5027859.001.jpg
case_images: fig1
case_images: The patient underwent transsphenoidal resection in August 2013 (Figure 1).
case_images: Coronal and sagittal MRI T1 sequence with gadolinium. Intra- and suprasellar tumor with tumor growth related to previous study.
case_images: CRIE2018-5027859.002.jpg
case_images: PMC5949168_01_CRIE2018-5027859.002.jpg
case_images: fig2
case_images: In March 2016, a new MRI with a focus on the sellar region was performed, finding tumor remnant growth (Figures 2(a) and 2(b)).
case_images: Sagittal and coronal MRI T1 sequences with gadolinium. Residual tumoral tissue only located intrasellar and right parasellar after second surgery.
case_images: CRIE2018-5027859.003.jpg
case_images: PMC5949168_01_CRIE2018-5027859.003.jpg
case_images: fig3
case_images: After the annual biochemical monitoring of the gonadal hormones, it was concluded that the gonadotropinoma became functional, so it was decided to surgically intervene by transcranial approach that resulted in a significant reduction of the tumor lesion (Figures 3(a) and 3(b)).
case_images: Micrography of immunohistochemistry staining with Streptavidina-Biotine technique revealed with diaminobenzidine. (a) Nuclear expression of SF-1 in the first surgery ((a), arrows). (b) Intense positivity for the FSH hormone in the second surgery ((b), arrows) (x400).
case_images: CRIE2018-5027859.004.jpg
case_images: PMC5949168_01_CRIE2018-5027859.004.jpg
case_images: fig4
case_images: Histologically tumors cells arranged in papillary pattern were found (Figures 4(a) and 4(b)).