case_images: PMC3276072_01
case_images: Secretory carcinoma shows microcystic pattern and intraluminal secretion, (a) (H&E) and (b) (PAS).
case_images: IJBC2011-704657.001.jpg
case_images: PMC3276072_01_IJBC2011-704657.001.jpg
case_images: fig1
case_images: Microscopic examination revealed the classical features of secretory carcinoma with a microcystic pattern (Figure 1(a)) with abundant intra and extracellular PAS-positive secretory material (Figure 1(b)).
case_images: The tumor cells show positive nuclear and cytoplasmic staining by S100 antibody (a) positive cytoplasmic staining by EMA antibody, (b) positive cytoplasmic staining by pan cytokeratin, (c) and some showed positive nuclear staining by ER antibody (d).
case_images: IJBC2011-704657.002.jpg
case_images: PMC3276072_01_IJBC2011-704657.002.jpg
case_images: fig2
case_images: On immunohistochemistry, the tumor cells were positive for EMA and S-100 protein and focally positive for cytokeratine and ER (Figures 2(a), 2(b), 2(c), and 2(d)) but negative for progesterone receptor, CD34, and CEA (Dako, Carpinteria, CA, USA).