case_images: PMC11191520_01
case_images: CT images of EBV-positive inflammatory FDCS. (a) and (e) represent non-contrast images, revealing two cystic-solid soft tissue masses. (b)-(d) and (f)-(h) correspond to contrast-enhanced arterial, venous, and delayed phase images, illustrating moderately uneven enhancement along the edges and within the solid components of the masses. Patchy non-enhanced areas are observed internally.
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case_images: Imaging findings were as follows: CT scans showed significant splenomegaly with two irregular soft tissue density masses in the spleen, measuring 5.6 cm  5.2 cm  4.3 cm (Fig. 1(a-d)) and 9.2 cm  6.3 cm  6.3 cm (Fig. 1(e-h)), respectively.
case_images: PET/CT images of EBV-positive inflammatory FDCS, which reveal increased metabolic activity within the masses. (a) The tumor SUV is 10.8, (b) The tumor SUV is 8.3.
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case_images: The remaining splenic parenchyma exhibited diffuse increased glucose metabolism, with a max SUV of approximately 2.9 (Fig. 2(a-b)).
case_images: Tumor pathology images under microscope. (a) HE  40, low magnification. Under the microscope, tumor cells are observed arranged in small clusters or cord-like structures (black arrows), with abundant lymphocytes dispersed between them (red arrows). (b) HE  200, high magnification. Under the microscope, tumor cells appear spindle-shaped or oval (black arrows), arranged around multinucleated giant cells (red arrows) to form granulomatous structures (yellow arrows). In areas lacking multinucleated giant cells, tumor cells are arranged in clusters and interwoven cord-like structures (green arrows).
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case_images: Some areas exhibited interstitial infiltration of tissue cells and eosinophils (Fig. 3(a-b)).