case_images: PMC10559491_01
case_images: (a) Swelling over the left parietal scalp region; (b) contrast-enhanced computed tomography brain shows destructive mildly enhancing bony mass lesion; (c) aspirate from scalp swelling showing round cells with moderate amount of cytoplasm in sheets and groups with mild nuclear atypia (x 400, Papanicolaou stain); and (d) round cells arranged in small groups and clusters with central nuclei and moderate amount of granular cytoplasm (x400, May-Grunwald- Giemsa stain).
case_images: Cytojournal-20-33-g001.jpg
case_images: PMC10559491_01_Cytojournal-20-33-g001.jpg
case_images: F1
case_images: Clinical picture, contrast-enhanced computed tomography (CECT), and cytomorphology of fine-needle aspirate are shown in Figure 1. The scalp swelling was [Figure 1a] on CECT brain revealed a destructive, mildly enhancing bony mass lesion with intra- and extra-cranial extension in the left parietal bone [Figure 1b]. The aspirate from scalp swelling of moderate cellularity showing round cells with central nucleus with nuclear dysplasia in the form of high nucleocytoplasmic ratio, nuclear enlargement, mild-to-moderate pleomorphism, and binucleation [Figures 1c, d and 2a, b].
case_images: (a) May-Grunwald-Giemsa stained smear from scalp swelling showing the cohesive sheet of round cells with large central nuclei and moderate granular cytoplasm. Occasional binucleation also noted (x400) and (b) Papanicolaou stained smear showing round cells with moderate amount of granular cytoplasm in sheet with well-defined cell border (x400).
case_images: Cytojournal-20-33-g002.jpg
case_images: PMC10559491_01_Cytojournal-20-33-g002.jpg
case_images: F2
case_images: The aspirate from scalp swelling of moderate cellularity showing round cells with central nucleus with nuclear dysplasia in the form of high nucleocytoplasmic ratio, nuclear enlargement, mild-to-moderate pleomorphism, and binucleation [Figures 1c, d and 2a, b].
case_images: (a and b) Aspirate from thyroid showing the sheet of Hurthle cells with moderate amount of granular cytoplasm in sheet with well-defined cell border with central round nucleus and occasional binucleation (x400).
case_images: Cytojournal-20-33-g003.jpg
case_images: PMC10559491_01_Cytojournal-20-33-g003.jpg
case_images: F3
case_images: Ultrasound-guided aspirate from thyroid showed similar morphology as seen in scalp swelling [Figure 3a and b].