case_images: PMC11048278_01
case_images: Serial chest CT scans at D1, D10, and D30 during the anti-infection period: (A) the initial CT scan at D1 showed an increased texture of both lungs increased, with multiple slight exudations and a small pleural effusion; (B) CT scan on D10 after admission revealed multiple progressive patchy shadows on both lungs, with ground-glass opacities and inflammatory exudates; (C) the follow-up CT scan on D30 after admission showed resolution of the bilateral diffuse patchy shadows, and increased multiple nodules increased in both lungs, with no pleural effusion. CT, computed tomography.
case_images: IDR-17-1583-g0001.jpg
case_images: PMC11048278_01_IDR-17-1583-g0001.jpg
case_images: f0001
case_images: The patient underwent a computed tomography (CT) examination after admission (Figure 1A), which indicated that two lung infections should be considered first. However, after four days of continued treatment, a reexamination CT scan indicated the progression of the infection (Figure 1B). PJP treatment continued for 30 days, and pulmonary infection lesions were completely relieved (Figure 1C).
case_images: Temperature trend chart and anti-infection summary during the hospital stay. Trimethoprim-sulfamethoxazole (TMP-SMX) 1.44 g qid (D1-D6) and 0.96 g qid (D7-D30), micafungin 0.2 g qd (D7-D10), caspofungin 50 mg qd (D11-D30), HRLfx (D1-D10) [R(rifampicin) 0.6 g qd, H(isoniazid) 0.3 g qd and Lfx(levofloxacin) 0.5 g qd], meropenem 1 g q8h (D1-D14), cefoperazone-sulbactam 2 g q8h (D15-D21) and teicoplanin 400 mg qd (D10-D17).
case_images: IDR-17-1583-g0002.jpg
case_images: PMC11048278_01_IDR-17-1583-g0002.jpg
case_images: f0002
case_images: The patient's high fever remained unrelieved, with a temperature as high as 40.4 C (see Figure 2 for the temperature trend chart) accompanied by shortness of breath and chest tightness.