case_images: PMC3934613_01
case_images: Clinical appearance at initial presentation. Grouped vesicular lesions are visible on the vulva, showing a typical 'frog spawn' appearance.
case_images: cde-0006-0001-g01.jpg
case_images: PMC3934613_01_cde-0006-0001-g01.jpg
case_images: F1
case_images: A 16-year-old Japanese girl presented with a 9-year history of vesicles on both sides of the vulva (fig. 1).
case_images: Histopathologic analysis reveals multiple thin-walled, dilated lymphatic spaces within the papillary dermis. Hematoxylin and eosin staining at low magnification.
case_images: cde-0006-0001-g02.jpg
case_images: PMC3934613_01_cde-0006-0001-g02.jpg
case_images: F2
case_images: Histopathologic examination revealed multiple thin-walled, dilated lymphatic spaces that contained lymphocytes and erythrocytes in the papillary dermis (fig. 2).
case_images: Clinical appearance after final laser treatments. No recurrence has occurred after 2 years, but follow-up is continuing.
case_images: cde-0006-0001-g03.jpg
case_images: PMC3934613_01_cde-0006-0001-g03.jpg
case_images: F3
case_images: No recurrence has been detected yet, 2 years after the last treatment, although follow-up is continuing (fig. 3).