case_images: PMC6717731_01
case_images: Peripheral blood smear with a nucleated red blood cell, polychromasia, "fragmented" RBCs and thrombocytopenia. The arrow points to a dysmorphic "fragmented" RBC (Wright 's stain, original magnification x1000).
case_images: CPAA-11-127-g0001.jpg
case_images: PMC6717731_01_CPAA-11-127-g0001.jpg
case_images: F0001
case_images: His peripheral blood smear was reviewed, and it showed nucleated RBCs, anisopoikilocytes, schistocytes, hypersegmented neutrophils (not captured) and very few platelets (Figure 1).
case_images: Timeline summary showing gradual improvement of ongoing hemolysis demonstrated by decreasing bilirubin and serum lactate dehydrogenase (LDH) levels.
case_images: CPAA-11-127-g0002.jpg
case_images: PMC6717731_01_CPAA-11-127-g0002.jpg
case_images: F0002
case_images: ADAMTS13 activity came back normal at 61% (>=60%). Accordingly, plasmapheresis was discontinued, parenteral B12 replacement was continued which resulted in cessation of hemolysis (Figure 2) and normalization of hemoglobin and platelets (Figure 3).
case_images: Timeline summary showing gradual improvement of anemia and thrombocytopenia demonstrated by increasing hemoglobin (Hb) and platelets. Two packed red blood cells were transfused on day 0 and day 4.
case_images: CPAA-11-127-g0003.jpg
case_images: PMC6717731_01_CPAA-11-127-g0003.jpg
case_images: F0003
case_images: ADAMTS13 activity came back normal at 61% (>=60%). Accordingly, plasmapheresis was discontinued, parenteral B12 replacement was continued which resulted in cessation of hemolysis (Figure 2) and normalization of hemoglobin and platelets (Figure 3).