case_images: PMC10469863_01
case_images: Patient's family tree.
case_images: fgene-14-1213283-g001.jpg
case_images: PMC10469863_01_fgene-14-1213283-g001.jpg
case_images: F1
case_images: Lymphoscintigraphy: Lack of superficial and deep lymphatics in the right lower limb Lymphatic malformations are often associated to Klippel Trenaunay malformation.
case_images: fgene-14-1213283-g002.jpg
case_images: PMC10469863_01_fgene-14-1213283-g002.jpg
case_images: F2
case_images: A lymphoscintigraphy documented a lack of deep and superficial lymphatic vessels (Figure 2).
case_images: T(1) weighted picture of the leg.
case_images: fgene-14-1213283-g003.jpg
case_images: PMC10469863_01_fgene-14-1213283-g003.jpg
case_images: F3
case_images: At 56 years of age, she had developed a moderately differentiated squamous cell carcinoma at the angiodysplastic lesion site as shown by MRI (Figure 3).
case_images: Preoperative picture of the right leg.
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case_images: PMC10469863_01_fgene-14-1213283-g004.jpg
case_images: F4
case_images: The carcinoma had been surgically removed (Figures 4, 5) and coverage of the local flap performed with a skin graft (Figure 6).
case_images: Operatory specimen.
case_images: fgene-14-1213283-g005.jpg
case_images: PMC10469863_01_fgene-14-1213283-g005.jpg
case_images: F5
case_images: The carcinoma had been surgically removed (Figures 4, 5) and coverage of the local flap performed with a skin graft (Figure 6). We also obtained angiodysplastic lesion and squamous cell carcinoma tissues from previous surgery (Figure 5) and Oncomine Pancancer analysis was performed on FFPE vascular lesion tissue and squamous cell carcinoma tissue.
case_images: Healing of the surgical wound with skin graft.
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case_images: PMC10469863_01_fgene-14-1213283-g006.jpg
case_images: F6
case_images: The carcinoma had been surgically removed (Figures 4, 5) and coverage of the local flap performed with a skin graft (Figure 6).
case_images: T(2) weighted picture of the lower limbs. Hypertrophy of the soft tissues is present together with dilated ectatic superficial and deep veins. Presence of a neoplastic tissue involving skin and subcutaneous tissue on the peroneal side of the right lower limb.
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case_images: PMC10469863_01_fgene-14-1213283-g007.jpg
case_images: F7
case_images: At 58 years of age, in October 2013, she had presented a relapse of a well-differentiated and keratinizing squamous cell carcinoma (Figures 7, 8).
case_images: Local recurrence direct phlebography with blue patent. Evidence of dermal backflow.
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case_images: PMC10469863_01_fgene-14-1213283-g008.jpg
case_images: F8
case_images: At 58 years of age, in October 2013, she had presented a relapse of a well-differentiated and keratinizing squamous cell carcinoma (Figures 7, 8).
case_images: Ct scan demonstrating a mass in the left lung.
case_images: fgene-14-1213283-g009.jpg
case_images: PMC10469863_01_fgene-14-1213283-g009.jpg
case_images: F9
case_images: A bronchoscopy was performed and the analysis of the bronchial aspirate showed the presence of Non-Small-Cell Lung Cancer (NSCLC) as observable in the TC scan sections (Figures 9, 10).
case_images: Ct scan demonstrating a mass in the right lung.
case_images: fgene-14-1213283-g010.jpg
case_images: PMC10469863_01_fgene-14-1213283-g010.jpg
case_images: F10
case_images: A bronchoscopy was performed and the analysis of the bronchial aspirate showed the presence of Non-Small-Cell Lung Cancer (NSCLC) as observable in the TC scan sections (Figures 9, 10).