case_images: PMC10867168_01
case_images: ICI-induced SCLE clinical appearance. Several photo-distributed oval pink to violaceous scaly papules and plaques on the upper back (A), dorsal forearm (B), and upper arm (C) are shown above.
case_images: fmed-11-1334718-g001.jpg
case_images: PMC10867168_01_fmed-11-1334718-g001.jpg
case_images: fig1
case_images: Physical examination revealed several photo-distributed oval pink to violaceous scaly papules and plaques on the bilateral dorsal forearms, upper arms, upper chest, and upper back (Figure 1).
case_images: ICI-induced SCLE histopathologic appearance. Histopathologic sections of a hematoxylin and eosin-stained skin biopsy revealed vacuolar interface change along the dermal-epidermal junction associated with dyskeratotic keratinocytes and a perivascular lymphocytic infiltrate at 20x (A) and 100x (B) magnification.
case_images: fmed-11-1334718-g002.jpg
case_images: PMC10867168_01_fmed-11-1334718-g002.jpg
case_images: fig2
case_images: Skin biopsy showed vacuolar interface dermatitis with a superficial lichenoid and perivascular lymphocytic infiltrate, consistent with a drug eruption (Figure 2).