case_images: PMC9132688_01
case_images: (a) A low-power view of the ileal biopsy specimen (hematoxylin and eosin stain; original magnification x40). (b) Amorphous eosinophilic deposits are apparent on the vessel wall (hematoxylin-eosin stain, original magnification x200). (c) Immunohistochemically, deposits show positive staining for beta2-microglobulin (original magnification x200).
case_images: CRID2022-9098201.001.jpg
case_images: PMC9132688_01_CRID2022-9098201.001.jpg
case_images: fig1
case_images: Histopathological examination of the specimen from ileal biopsy showed amorphous eosinophilic deposits on the vessel wall (Figures 1(a) and 1(b)). Immumohistochemically, deposits were positive for beta2m (Figure 1(c)).
case_images: A collection of whitish-yellow papules is evident on the ventral surface of the tongue tip.
case_images: CRID2022-9098201.002.jpg
case_images: PMC9132688_01_CRID2022-9098201.002.jpg
case_images: fig2
case_images: On oral examination, a collection of painless, relatively hard, rugged whitish-yellow papules was found on the ventral surface of the tongue tip (Figure 2).
case_images: (a) Amorphous extracellular eosinophilic deposits are shown in the subepithelial region (hematoxylin-eosin stain, original magnification x100). (b) Extracellular deposits show positive staining with direct fast scarlet (DFS) (original magnification x100). (c) Extracellular deposits show positive staining with potassium permanganate- (KMnO4-) DFS stain (original magnification x100). (d) Staining for beta2-microglobulin is also positive (original magnification x100).
case_images: CRID2022-9098201.003.jpg
case_images: PMC9132688_01_CRID2022-9098201.003.jpg
case_images: fig3
case_images: Histopathologically, the specimen showed amorphous eosinophilic extracellular deposits in the subepithelial region (Figure 3(a)). Extracellular deposits showed positive results from DFS staining, and also from potassium permanganate- (KMnO4-) DFS staining and beta2m staining (Figures 3(b)-3(d)).