case_images: PMC8079193_01
case_images: Scrotal ultrasound.
case_images: CRIU2021-6692578.001.jpg
case_images: PMC8079193_01_CRIU2021-6692578.001.jpg
case_images: fig1
case_images: An ultrasound was requested, showing a heterogeneous left testicle with small rounded hypoechoic areas, increased blood flow, and small echogenic foci along the rete testis with moderate left hydrocele (Figure 1).
case_images: Gross specimen testicular tumor.
case_images: CRIU2021-6692578.002.jpg
case_images: PMC8079193_01_CRIU2021-6692578.002.jpg
case_images: fig2
case_images: A separate, well-demarcated, nearly round tumor nodule was present in the head of the epididymis (Figure 2).
case_images: Esophageal tissue (left): sheets of neoplastic cells with high nucleus/cytoplasm ratio and nuclear hyperchromasia and pleomorphism. Immunohistochemical staining was positive for monoclonal CEA and negative for p63, synaptophysin, and chromogranin, supporting a diagnosis of poorly differentiated adenocarcinoma (H&E; x12.5). Testicular tissue (right): poorly differentiated and loosely cohesive carcinoma with predominantly solid and some focal glandular architecture demonstrating considerable pleomorphism. Adjacent seminiferous tubule (H&E; x10).
case_images: CRIU2021-6692578.003.jpg
case_images: PMC8079193_01_CRIU2021-6692578.003.jpg
case_images: fig3
case_images: Histologically, the tumor in the testis was markedly similar to that in the esophagus, with both showing a majority solid growth pattern and focal glandular differentiation (Figure 3).