case_images: PMC5726692_01
case_images: Irregular, asymmetric pigmented lesion on the left nasal root
case_images: abd-92-05-s1-0101-g01.jpg
case_images: PMC5726692_01_abd-92-05-s1-0101-g01.jpg
case_images: f1
case_images: Examination revealed an ill-defined 15 mm x 7 mm macule with an irregular shape and asymmetrical distribution of the pigment network (Figure 1).
case_images: A: Hematoxylin & eosin staining of melanoma in
  situ with follicular involvement and syringoma structures
  in the middle dermis (X2). B: Detail of the collision
  between the melanoma in situ and the syringoma (X200)
case_images: abd-92-05-s1-0101-g02.jpg
case_images: PMC5726692_01_abd-92-05-s1-0101-g02.jpg
case_images: f2
case_images: In the upper and middle dermis there were clusters of small ducts, occasionally with comma-shaped extensions, lined by a double-layered epithelium typical of a syringoma (Figure 2).
case_images: A: Melan-A staining showing the melanoma in
  situ with follicular involvement (x200). Duct structures do
  not stain. B: CEA staining showing the ducts of the
  syringoma (X100)
case_images: abd-92-05-s1-0101-g03.jpg
case_images: PMC5726692_01_abd-92-05-s1-0101-g03.jpg
case_images: f3
case_images: Immunohistochemical staining confirmed that melanoma was positive for Melan-A and HMB45 and that syringoma was positive for the carcinoembryonic antigen (CEA) (Figure 3).