case_images: PMC7291867_01
case_images: Multimodal imaging. (A) Brain MRI plain scan and enhancement. The brain MRI scan showed the brain was scattered with ischemic foci. (B) Abdominal three-dimensional CT and enhancements. The yellow arrow indicates the location of the primary retroperitoneal tumor. (C) Abdominal three-dimensional CT and enhancements. The yellow arrow indicates the location of the recurrent retroperitoneal tumor. (D) Chest CT. The yellow arrows indicate metastatic tumors in the lungs.
case_images: fphar-11-00843-g001.jpg
case_images: PMC7291867_01_fphar-11-00843-g001.jpg
case_images: f1
case_images: The blood pressure was 164/109mm Hg, brain MRI plain scan and enhancement showed the brain was scattered with ischemic foci, without other special problems. (Figure 1A). Her past medical history included an operation for retroperitoneal leiomyosarcoma in 2016. (Figure 1B). Adriamycin, Ifosfamide and Dacarbazine) for nearly 6 months at Sun Yat-sen University Cancer Center. Apart from gastrointestinal discomfort, like nausea and vomiting, no other serious complications were present (Figures 1C, D).
case_images: Multimodal imaging. (A) Ultra-wide field retinophotography of both eyes showing cotton-wool spots, widespread hemorrhage, and stellate exudation. (B) Horizontal Spectral Domain optical coherence tomography (SD-OCT) B-scan through the fovea of both eyes showing a regression of the exudative retinal detachment, ectoretina atrophy and hard exudations between the retinal layers.
case_images: fphar-11-00843-g002.jpg
case_images: PMC7291867_01_fphar-11-00843-g002.jpg
case_images: f2
case_images: Horizontal Spectral Domain optical coherence tomography (SD-OCT) B-scan through the fovea showed ectoretina atrophy and hard exudations between the retinal layers, indicating possible exudative retinal detachment after occurrence (Figure 2).
case_images: Multimodal imaging. (A) Fundus autofluorescence of both eyes revealing areas of hypo-autofluorescence due to retinal hemorrhages and cotton-wool spots, and annular hyper-autofluorescence in macular area due to hard exudation. (B) Early phase of Fluorescein Angiography (FFA) revealing areas of hypofluorescence. (C) Early phase of Indocyanine Green Angiography (ICGA) seeming normal. (D) Late phase of FFA showing hyperfluorescent spots. (E) Late phase of ICGA showing hypofluorescence areas.
case_images: fphar-11-00843-g003.jpg
case_images: PMC7291867_01_fphar-11-00843-g003.jpg
case_images: f3
case_images: Indocyanine green angiographyn (ICGA) was normal in the early phase and showed hypofluorescence areas in the late phase (Figure 3).