case_images: PMC8559647_01
case_images: Wilms' tumor composed of tubuloglandular and mesenchymal component. A) (40x, H&E stain). B) (200x, H&E stain).C) rosette- like structure (400x, H&E stain). D) mesenchymal stroma (400x, H&E stain)
case_images: cjim-12-421-g001.jpg
case_images: PMC8559647_01_cjim-12-421-g001.jpg
case_images: F1
case_images: In abdominal and pelvic computed tomography (CT) scan with and without contrast, solid and hypodense mass involving the upper half right kidney was detected with approximately 128x100 mm in diameter (figure1).
case_images: Immunohistochemical staining A) WT1 B) WT1 (repeat)
case_images: cjim-12-421-g002.jpg
case_images: PMC8559647_01_cjim-12-421-g002.jpg
case_images: F2
case_images: In the light microscopic examination, the tumor was composed of tubular and rosette-like structures covered by simple to pseudo-stratified columnar epithelium with elongated, vesicular nuclei with acidophilic cytoplasm, occasionally with intraluminal papillary projection, enclosed in fascicular mesenchymal stroma, fibrous and hyalinized areas (figure2).
case_images: Immunohistochemical staining A) Chromogranin B) Synaptophysin C) EMA D) CK E) CD10 F) HMB45 G) CD 56
case_images: cjim-12-421-g003.jpg
case_images: PMC8559647_01_cjim-12-421-g003.jpg
case_images: F3
case_images: WT1, CD10, CD99, synaptophysin, chromogranin was done. WT1 (with twice repeat) was non-specific (figure 3), EMA was positive and other markers were negative (figure 4).