case_images: PMC10981217_01
case_images: Changes in levels of WBC and HGB of the patient during the observational period.. WBC: white blood cell count, normal range: 3.5-9.5 x 109/L; HGB: hemoglobin, normal range: 130-175 g/L.
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case_images: PMC10981217_01_10.1177_2050313X241240097-fig1.jpg
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case_images: The patient's hemoglobin level showed a progressive downward trend after admission (Figure 1), indicating the presence of normal pigmented anemia. Laboratory markers associated with infection, including elevated white blood cell count (WBC), interleukin-6 (IL-6), and C-reactive protein (CRP) (Figure 1 shows changes in leukocyte levels, Figure 2 for changes in IL-6 and CRP levels). WBC, hemoglobin levels (Figure 1), CRP, and IL-6 levels (Figure 2) demonstrated notable decreases, indicating the resolution of systemic inflammation.
case_images: Changes in levels of CRP and IL-6 of the patient during the observational period.. IL-6: serum interleukin-6, normal range: 0-pg/ml; CRP: serum C-reactive protein, normal range: 0-8 mg/L.
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case_images: PMC10981217_01_10.1177_2050313X241240097-fig2.jpg
case_images: fig2-2050313X241240097
case_images: Laboratory markers associated with infection, including elevated white blood cell count (WBC), interleukin-6 (IL-6), and C-reactive protein (CRP) (Figure 1 shows changes in leukocyte levels, Figure 2 for changes in IL-6 and CRP levels). WBC, hemoglobin levels (Figure 1), CRP, and IL-6 levels (Figure 2) demonstrated notable decreases, indicating the resolution of systemic inflammation.
case_images: Changes in levels of Scr and ALB of the patient during the observational period.. Scr: serum creatinine, normal range: 57-111 umol/L; ALB: serum albumin, normal range: 40-55 g/L.
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case_images: PMC10981217_01_10.1177_2050313X241240097-fig3.jpg
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case_images: Laboratory markers associated with infection, including elevated white blood cell count (WBC), interleukin-6 (IL-6), and C-reactive protein (CRP) (Figure 1 shows changes in leukocyte levels, Figure 2 for changes in IL-6 and CRP levels). In addition, the patient's serum creatinine level decreased after antibiotic treatment, suggesting that anti-infective therapy was effective (Figure 3). Additionally, serum creatinine and serum albumin levels (Figure 3) displayed improvements, signifying stable kidney function and enhanced nutritional status facilitated by anti-infective therapy and nutritional support.
case_images: The chest CT scan of the patient at admission (December 6, 2021) showed the presence of bilateral pneumonia with mild interstitial pulmonary edema and bilateral pleural effusion (a). The bilateral ground-glass opacities and pleural effusion had been absorbed after treatment (December 24, 2021) (b).
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case_images: PMC10981217_01_10.1177_2050313X241240097-fig4.jpg
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case_images: Laboratory markers associated with infection, including elevated white blood cell count (WBC), interleukin-6 (IL-6), and C-reactive protein (CRP) (Figure 1 shows changes in leukocyte levels, Figure 2 for changes in IL-6 and CRP levels). The patient's initial chest CT scan upon admission revealed bilateral pneumonia with mild interstitial pulmonary edema and bilateral pleural effusion (Figure 4(a)). Subsequent chest CT scans during the follow-up period showed an obvious improvement in these pulmonary abnormalities (Figure 4(b)).
case_images: Histological characterization of the left inguinal lymph node of the patient revealed the following findings. (a) The general view of the lymph node. The lymph node structure was partially preserved, but extensive fibrosis was observed in most areas. The lymph sinuses were open, and there was partial lymph follicle atrophy. Scattered plasma cells were present in the interfollicular regions, and occasional infiltration of eosinophils was observed at low magnification (b) and high magnification (c). (d) Immunohistochemical staining of CD138, which is specific to plasma cells.
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case_images: PMC10981217_01_10.1177_2050313X241240097-fig5.jpg
case_images: fig5-2050313X241240097
case_images: Laboratory markers associated with infection, including elevated white blood cell count (WBC), interleukin-6 (IL-6), and C-reactive protein (CRP) (Figure 1 shows changes in leukocyte levels, Figure 2 for changes in IL-6 and CRP levels). Scattered plasma cells were present in the interfollicular regions, occasionally accompanied by eosinophil infiltration (Figure 5(a)-(c)). Immunohistochemical staining displayed positive cells for CD138, a specific marker of plasma cells (Figure 5(d)), and negative results for HHV8.