case_images: PMC8580671_01
case_images: (a) & (b) X-rays in case 4: Skull lateral and AP view showing calvarian and basilar thickening, poorly developed sinuses and sclerosis of nasal bone; (c) X-ray hand showing bone in bone appearance; (d) X-ray lower limbs showing bone in bone appearance and increased bone density; (e) X-ray spine lateral view showing bone in bone appearance; (f) X-ray chest showing increased bone density in ribs and absence of corticomedullary differentiation.
case_images: CRIG2021-7133508.002.jpg
case_images: PMC8580671_01_CRIG2021-7133508.002.jpg
case_images: fig2
case_images: Skeletal survey showed typical bone in bone appearance in X-rays of hands, long bones, and spine lateral views; skull X-ray showed basilar thickening, nasal bone sclerosis, and poorly formed sinuses; and X-ray of chest showed poor corticomedullary differentiation and increased bone density in ribs (Figure 2).
case_images: PMC8580671_02
case_images: The X-ray of one hand with wrist in case 5-pycnodysostosis patient showing delayed bone age and acroosteolysis in the distal phalanges of thumb and index finger.
case_images: CRIG2021-7133508.003.jpg
case_images: PMC8580671_02_CRIG2021-7133508.003.jpg
case_images: fig3
case_images: X-ray of the hands revealed increased density of the bones, acroosteolysis in distal phalanges especially in the index finger and thumb and delayed bone age (Figure 3).
case_images: PMC8580671_03