case_images: PMC10637730_01
case_images: (a) Atypical clinical appearance: prominent tumor lesion on the thigh with satellite normochromic papules and nodules. (b) - Biopsy of one of the normochromic satellite papules presenting a patch stage, showing newly formed vessels protruding into a larger vascular space, which is characteristic of the promontory sign. (c) Plaque stage from a satellite nodule showing diffuse dermal vascular infiltrate, accompanied by increased cellularity. Notably, there are paranuclear vacuoles containing erythrocytes. (d) Nodular stage present in the main tumor lesion: a diffuse infiltrate of monomorphic spindled cells. (e) Positive immunochemistry for CD-34. (f) Positive immunochemistry for HHV-8.
case_images: 1678-9849-rsbmt-56-e0478-2023-gf1.jpg
case_images: PMC10637730_01_1678-9849-rsbmt-56-e0478-2023-gf1.jpg
case_images: f1
case_images: A 42-year-old male with a history of human immunodeficiency virus (HIV) infection, a CD4 cell count of >400/muL, and an undetectable viral load for six months presented with a tumoral lesion on his lower limb accompanied by satellite normochromic nodules (Figure 1a ). A skin biopsy revealed various stages of Kaposi sarcoma (KS) (Figures 1b-1f ).