case_images: PMC10210831_01
case_images: Diffuse ulceration and friability in the rectum and sigmoid colon.
case_images: CRIGM2022-2200438.001.jpg
case_images: PMC10210831_01_CRIGM2022-2200438.001.jpg
case_images: fig1
case_images: Extensive erythema, friability, and shallow ulcerations were noted extending from the anus up to 22 cm, at which point the procedure was aborted due to significant inflammation and the inability to traverse the rectum (Figures 1(a) and 1(b)).
case_images: Rectal mucosa with chronic active inflammation with plasma cells and neutrophilic crypts consistent with Crohn's disease, 200x.
case_images: CRIGM2022-2200438.002.jpg
case_images: PMC10210831_01_CRIGM2022-2200438.002.jpg
case_images: fig2
case_images: Subsequent pathology showed chronic and active colitis with plasma cells and crypts full of neutrophils, consistent with a definitive diagnosis of Crohn's disease (Figure 2).
case_images: Duodenal bulb, 2nd portion of the duodenum, and gastric antrum with multiple erosions and ulcerations.
case_images: CRIGM2022-2200438.003.jpg
case_images: PMC10210831_01_CRIGM2022-2200438.003.jpg
case_images: fig3
case_images: Esophagogastroduodenoscopy showed multiple nonbleeding, round, clean-based, and shallow ulcers ranging between 3-7 mm in the duodenal bulb and the 1st and 2nd parts of the duodenum (Figures 3(a)-3(c)).
case_images: Duodenal mucosa with active erosive chronic duodenitis, villous blunting and surface epithelium replaced by neutrophils consistent with duodenal Crohn's disease, 200x.
case_images: CRIGM2022-2200438.004.jpg
case_images: PMC10210831_01_CRIGM2022-2200438.004.jpg
case_images: fig4
case_images: Pathology showed fragments of duodenal mucosa with focal ulceration and acute inflammation with surface epithelium replaced by neutrophils and plasma cells, as well as moderately chronic, focally active gastritis with negative H pylori, establishing a diagnosis of gastroduodenal Crohn's disease (Figure 4).