case_images: PMC10693009_01
case_images: Imaging examination: a-c: In 2016, imaging revealed mild stenosis in the main portal vein. There was a conspicuous presence of collateral branches (indicated by the red arrow), facilitating the inflow of blood into the liver during the portal venous phase. Furthermore, the enhancement patterns observed in both the liver and spleen appeared uniform and essentially consistent.
case_images: j_biol-2022-0766-fig001.jpg
case_images: PMC10693009_01_j_biol-2022-0766-fig001.jpg
case_images: j_biol-2022-0766_fig_001
case_images: The results of the thoracic CT examination revealed the presence of bilateral pleural effusion, with a depth of 6.0 cm in the right pleural space and 3.7 cm in the left pleural space (as illustrated in Figures 1 and 2).
case_images: Imaging examination: (a) During reexamination in 2022: Significant worsening of main portal vein stenosis (indicated by the red arrow) with partial intrahepatic branches essentially having disappeared. In the portal venous phase of CT, significantly lower enhancement in most of the liver than in the spleen (indicated by the red arrow), significantly more aggravated portal hypertension, significantly thicker varices in the esophagus and stomach fundus, and a thicker splenorenal venous shunt. (b) The portal vein area shows thrombosis (indicated by the red arrow). (c) Spongy changes in the portal vein area (indicated by the red arrow). (d and e) Bilateral pleural effusion with no obvious signs of ascites.
case_images: j_biol-2022-0766-fig002.jpg
case_images: PMC10693009_01_j_biol-2022-0766-fig002.jpg
case_images: j_biol-2022-0766_fig_002
case_images: The results of the thoracic CT examination revealed the presence of bilateral pleural effusion, with a depth of 6.0 cm in the right pleural space and 3.7 cm in the left pleural space (as illustrated in Figures 1 and 2).
case_images: Hepatic pathology: Essentially normal liver tissue structure. Turbid and swollen hepatocytes. A small amount of pigment granule deposition in hepatocytes. Scattered punctate necrosis in the liver parenchyma. Narrowed sinusoids. Hepatic centrilobular vein not dilated. Normal shape and number of small bile ducts in the portal area. A small amount of chronic inflammatory cell infiltration in interstitial substance. No visible fibrous septa (hematoxylin and eosin [H&E] staining, x100-fold).
case_images: j_biol-2022-0766-fig003.jpg
case_images: PMC10693009_01_j_biol-2022-0766-fig003.jpg
case_images: j_biol-2022-0766_fig_003
case_images: No definite changes prompting cirrhosis (Figure 3).