case_images: PMC11001470_01
case_images: PMC11001470_02
case_images: PMC11001470_03
case_images: PMC11001470_04
case_images: PET scan showing infradiaphragmatic lymphadenopathies and retroperitoneal intercavoaortic lymphadenopathies, measuring 12 x 10 mm, maximum SUV of 9.8.
case_images: CRIID2024-8852063.001.jpg
case_images: PMC11001470_04_CRIID2024-8852063.001.jpg
case_images: fig1
case_images: A 18F-fluorodeoxyglucose (18-F) positron emission tomography scan (PET-CT) was requested, which revealed hypermetabolic retroperitoneal and intercavoaortic lymph nodes, measuring 12 x 10 mm, with a maximum standardized uptake value (SUV) of 9.8, inversion of liver/spleen metabolism, and hepatosplenomegaly (Figure 1).
case_images: PMC11001470_05
case_images: PMC11001470_06
case_images: Lymph node biopsies: (a) hematoxylin and eosin 5x; (b) CD20, highlighting the T cell lymphoid component; (c) CD3, highlighting the B cell lymphoid component; (d) SARS-CoV-2 positive cytoplasmic in macrophages (in red).
case_images: CRIID2024-8852063.002.jpg
case_images: PMC11001470_06_CRIID2024-8852063.002.jpg
case_images: fig2
case_images: The retroduodenal lymph node biopsy revealed sinusoidal and paracortical hyperplasia with small and medium lymphocytes, apoptotic cells, histocytes, plasmacytoid dendritic cells (CD123+), and hemophagocytes, with a few macrophages positive for SARS-CoV-2 in the cytoplasm (Figure 2).
case_images: PMC11001470_07
case_images: PMC11001470_08