case_images: PMC10080590_01
case_images: PMC10080590_02
case_images: CT scan of the thorax. (A) Right breast mass, arrowed. (B) Left breast mass, arrowed.
case_images: fonc-13-1034556-g001.jpg
case_images: PMC10080590_02_fonc-13-1034556-g001.jpg
case_images: f1
case_images: The mass was abutting the right pectoralis muscles with no clear fat plane at the central region (Figure 1A). A lobulated heterogeneously enhancing mass at the upper inner quadrant of the left breast extended to the retroareolar region, measuring 2.4 x 5.4 x 4.2 cm with calcifications and a necrotic center within (Figure 1B).
case_images: Photos of the patient. (A, B) Preoperatively, front and right lateral views. (C) Postoperatively, front.
case_images: fonc-13-1034556-g002.jpg
case_images: PMC10080590_02_fonc-13-1034556-g002.jpg
case_images: f2
case_images: The patient underwent bilateral mastectomy and axillary dissection successfully (Figures 2A-C).
case_images: Microscopic analysis of the right breast. (A) The right breast tumor shows hypercellularity [hematoxylin-eosin (H&E) staining, x4]. (B) The spindle-shaped cells are arranged in fascicles in a herringbone pattern (H&E, x20). (C) Focal leaf-like pattern typical of phylloides tumor with adjacent necrosis (H&E, x4). (D) The tumor is seen less than 1 mm from the inked deep margin (H&E, x4).
case_images: fonc-13-1034556-g003.jpg
case_images: PMC10080590_02_fonc-13-1034556-g003.jpg
case_images: f3
case_images: The right mastectomy specimen weighed 1.2 kg with a maximal diameter of 16 cm and was a malignant phylloides (Figure 3).
case_images: Microscopic analysis of the left breast. (A, B) The left breast tumor shows variable morphology of invasive carcinoma comprised of infiltrating small ducts, cords, and cribriform glands with a micropapillary pattern (H&E, x4). (C) Clusters of cells floating in mucin pools (H&E, x4). (D) The malignant cells display pleomorphic vesicular nuclei with inconspicuous nucleoli (H&E, x20).
case_images: fonc-13-1034556-g004.jpg
case_images: PMC10080590_02_fonc-13-1034556-g004.jpg
case_images: f4
case_images: It was an invasive carcinoma of no special type (ER positive 60%, PR positive 50%, and HER2 negative) (Figure 4).