case_images: PMC11319174_01
case_images: Patient's face during treatment with tetracyclines and rupatadine, showing multiple acne lesions characterized by redness and nodules particularly on the cheeks and forehead.
case_images: fmed-11-1450666-g001.jpg
case_images: PMC11319174_01_fmed-11-1450666-g001.jpg
case_images: fig1
case_images: A 14-year-old boy, suffering for about a year from acne (Figure 1) treated with tetracyclines and rupatadine, presented due to intensiving ankle and knee joint pain persisting of 2 weeks duration.
case_images: (A,B) Patient's face post-surgical procedures, depicting significant skin loss on both cheeks.
case_images: fmed-11-1450666-g002.jpg
case_images: PMC11319174_01_fmed-11-1450666-g002.jpg
case_images: fig2
case_images: During the patient's stay in the surgery department, extensive necrosis prompted surgical debridement of the facial lesions on two occasions (due to healing complications), resulting in skin loss on both cheeks (Figure 2).
case_images: Patient's face after treatment with isotretinoin and prednisone showing marked improvement.
case_images: fmed-11-1450666-g003.jpg
case_images: PMC11319174_01_fmed-11-1450666-g003.jpg
case_images: fig3
case_images: After a year of isotretinoin therapy significant improvement in acne lesions was observed (Figure 3).