case_images: PMC10884879_01
case_images: Imaging findings. Coronal STIR images (A, B, and C) show hyperintense lobulated lesions spanning the entire right side of the neck, extending from the base of the skull to the submandibular region inferiorly, and in the submental region (arrow). Sagittal (D) and axial (E and F) T2W images show multiple hyperintense lesions of similar morphology, involving the right side of the neck, the deep lobe of the parotid (asterisk), and the right submandibular gland. Post-contrast T1W images (G, H, and I) demonstrate enhancement within these lesions.. STIR: short tau inversion recovery; T2W: T2-weighted; T1W: T1-weighted
case_images: cureus-0016-00000052851-i01.jpg
case_images: PMC10884879_01_cureus-0016-00000052851-i01.jpg
case_images: FIG1
case_images: A few of the lesions also showed smooth peripheral enhancement (Figure 1).
case_images: Histopathological and immunohistochemical findings. A: A well-circumscribed tumor involving the salivary gland (x40, H and E). B: On higher power, the tumor is composed of a monomorphic biphasic population of polyhedral epithelial and spindle-shaped/angular myoepithelial cells, in a background of hyalinized areas representing chondromyxoid stroma (x200, H&E). C and D: Immunohistochemistry shows the epithelial cells to be positive for CK7 (C, x100, DAB), and the myoepithelial cells are positive for SOX10 (D, x100, DAB).. H&E: hematoxylin and eosin; CK7: cytokeratin-7; SOX10: SRY-box transcription factor 10; DAB: 3,3'-diaminobenzidine
case_images: cureus-0016-00000052851-i02.jpg
case_images: PMC10884879_01_cureus-0016-00000052851-i02.jpg
case_images: FIG2
case_images: Additional biopsy from the right submandibular gland was also done, which showed a low-grade salivary neoplasm arranged in clusters and tubules (Figure 2).