case_images: PMC11160389_01
case_images: Neurological Assessment Demonstrating Mild Postural and Intention Tremors with Preserved Proprioceptive Function. This video demonstrates a mild postural tremor involving distal joints of both hands rather than involvement of the wrist or elbow. A head tilt is noted to the right, and head tremor is irregular. On finger to nose maneuver, intention tremor is evident, although worse on the left, where mild dysmetria briefly evident. Romberg's sign is negative, indicating preserved proprioceptive function. Tandem gait abnormalities were not evident in this assessment.
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case_images: PMC11160389_01_.jpg
case_images: V1
case_images: A brain MRI revealed no cerebellar or cerebral atrophy, and no other structural abnormalities (Figure 1).
case_images: MRI shows no cerebral atrophy, no cerebellar atrophy, or other structural abnormalities.
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case_images: The patient's medical history revealed a familial pattern of tremor, with her father, grandmother, and aunt all having experienced similar symptoms of head and hand tremors (Figure 2A). The absence of this variation in her genome indicates a paternal inheritance of the condition, corroborating the patient's familial history (Figure 2B) and the observed phenotypic manifestations within the paternal lineage of the family.