case_images: PMC3891161_01
case_images: Uterine cervix punch biopsy shows invasive squamous cell carcinoma, keratinizing type. Hematoxylin and eosin stain (x200)
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case_images: F1
case_images: Microscopically, the biopsy specimen revealed a keratinizing type invasive squamous cell carcinoma (Figure 1).
case_images: Abdomen and pelvic MRI scan shows 5.5x3.5 cm high signal intensity mass in the uterine cervix.
case_images: kjim-20-247-g002.jpg
case_images: PMC3891161_01_kjim-20-247-g002.jpg
case_images: F2
case_images: There was a 5.5x3.5 cm high signal intensity mass in the uterine cervix with invasion of the left parametrium and a 1 cm lymph node in the left external iliac area on MRI scan (Figure 2).
case_images: Bone marrow examination shows granulocytic reactive marrow. No evidence of bone marrow involvement of malignant tumor was detected. Wright, Giemsa stain (x400).
case_images: kjim-20-247-g003.jpg
case_images: PMC3891161_01_kjim-20-247-g003.jpg
case_images: F3
case_images: There was no evidence of bone marrow involvement of malignant tumor (Figure 3).
case_images: Immunohistochemical staining of G-CSF(A), IL-6(B) (x200).
case_images: kjim-20-247-g004.jpg
case_images: PMC3891161_01_kjim-20-247-g004.jpg
case_images: F4
case_images: Staining for G-CSF and IL-6 was mainly observed in the cytoplasm of cancer cells (Figure 4A, 4B).
case_images: Follow-up abdomen and pelvic MRI scan shows no cervical mass.
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case_images: F5
case_images: After these treatments, the cervical mass was no longer seen in the follow up MRI scan (Figure 5).
case_images: Follow-up chest X-ray shows markedly increased metastatic nodules of right lower lobe and left upper lobe and newly developed metastatic nodule in right upper lobe.
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case_images: PMC3891161_01_kjim-20-247-g006.jpg
case_images: F6
case_images: After four cycles of treatment, a marked increase in metastatic lung nodules was found on the follow-up chest X-ray (Figure 6), with severe granuocytosis (52,700/microL).