case_images: PMC1906873_01
case_images: Case 1: T1-weighted magnetic resonance (MR) demonstrating stress fractures of (a) right talus and (b) left calcaneum.
case_images: SRCM2007-91586.001.jpg
case_images: PMC1906873_01_SRCM2007-91586.001.jpg
case_images: F1
case_images: Though the possibility of skeletal metastases was considered, careful review of plain radiographs revealed insufficiency fractures of both ankles, confirmed on magnetic resonance (MR) scan (Figure 1).
case_images: PMC1906873_02
case_images: Case 2: isotope bone scans, (a) at diagnosis, demonstrating increased uptake at site of primary tumor in left tibia, (b) after ifosfamide therapy and surgery, demonstrating continued increased uptake at site of primary tumor and new abnormality in region of right ankle.
case_images: SRCM2007-91586.002b.jpg
case_images: PMC1906873_02_SRCM2007-91586.002b.jpg
case_images: F2
case_images: Initial isotope bone scan is shown in Figure 2(a). Isotope bone scan added to suspicion of metastases, with several areas of increased uptake evident  (Figure 2(b)).
case_images: PMC1906873_03