case_images: PMC6237918_01
case_images: Skin lesions before rituximab treatment.
case_images: fmed-05-00315-g0001.jpg
case_images: PMC6237918_01_fmed-05-00315-g0001.jpg
case_images: F1
case_images: The clinical examination revealed multiple erythematous papules and plaques with crusts on his back, chest, face, and scalp (about 40% of body surface area was involved) with no mucosal involvement (Figure 1).
case_images: Clinical picture eight months after initial rituximab treatment.
case_images: fmed-05-00315-g0002.jpg
case_images: PMC6237918_01_fmed-05-00315-g0002.jpg
case_images: F2
case_images: Therefore, two rituximab infusions (1 g each) were administered 2 weeks apart leading to a near-complete b-cell depletion in peripheral blood, a decrease in Dsg1 antibody levels (below the detection range), and an almost complete remission of the skin lesions within the next year (Figure 2).