case_images: PMC11249558_01
case_images: Case 1. a Initial application of the synthetic hybrid-scale fiber matrix to pharyngeal pharyngocutaneous fistula. b Mepitel dressing sutured over the synthetic matrix. c 38 days after synthetic matrix application. d 86 days after synthetic matrix application.
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case_images: F1
case_images: The synthetic matrix was sutured in place using 3-0 vicryl on an SH-1 needle and covered using Mepitel Burn, sutured down using 2-0 Silk on an SH-1 needle (Fig. 1a). A Xeroform dressing was placed overtop and changed daily (Fig. 1b). The patient continued to follow up on a regular basis to monitor wound healing progress (Fig. 1c). Complete re-epithelialization was achieved 86 days after the initial application of the synthetic hybrid-scale fiber matrix (Fig. 1d).
case_images: PMC11249558_02
case_images: Case 2. a Initial application of the synthetic hybrid-scale fiber matrix to defect of ventral tongue and floor of mouth. b After bolster removal and 2 weeks after synthetic matrix application. c Fully healed at 5 weeks after synthetic matrix application.
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case_images: PMC11249558_02_cro-2024-0017-0001-539200_F02.jpg
case_images: F2
case_images: A 5 cm x 7 cm sheet of synthetic hybrid-scale fiber matrix was placed on the wound bed and sutured in place using 3-0 vicryl on an SH-1 needle (Fig. 2a). A bolster was left in place for 14 days and subsequently removed without difficulty in clinic (Fig. 2b). Complete resolution and mucosal healing was noted at 4 weeks post-operatively (Fig. 2c).
case_images: PMC11249558_03
case_images: PMC11249558_04
case_images: Case 4. a 7 days after application of the synthetic hybrid-scale fiber matrix to radial forearm donor site. b Increased granulation tissue observed in wound bed 14 days after synthetic matrix application. c 6 weeks after synthetic matrix application. d 12 weeks after synthetic matrix application.
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case_images: PMC11249558_04_cro-2024-0017-0001-539200_F03.jpg
case_images: F3
case_images: The wound was photographed at multiple time periods in the healing phase (Fig. 3a-c), and complete resolution of the wound was observed at 12 weeks post-operatively in clinic (Fig. 3d).