case_images: PMC3861609_01
case_images: (A) Hematoxylin and eosin staining of the tumor cells in the rectum, lung and tonsil. (B) Immunohistochemical staining of the lung showed CDX-2(+), muc-1(+), CK7(+) and TTF-1(-) in the tumor cells. Immunohistochemical staining of the tonsil showed CDX-2(-), CK20(+), CK7(-) and TTF-1(-) in the tumor cells, confirming metastasis from colorectal adenocarcinoma (magnification, x400). CDX-2, caudal type homeobox transcription factor 2; muc-1, mucin-1; CK7, cytokeratin 7; TTF-1, thyroid transcription factor-1.
case_images: OL-07-01-0153-g00.jpg
case_images: PMC3861609_01_OL-07-01-0153-g00.jpg
case_images: f1-ol-07-01-0153
case_images: The tumor was diagnosed as invading the visceral pleura and immunohistochemical staining showed caudal-type homeobox transcription factor 2 (CDX-2)(+), mucin-1(+), cytokeratin 7 (CK7)(+) and thyroid transcription factor-1 (TTF-1)(-) in the tumor cells (Fig. 1). TTF-1(-) in the tumor cells, confirming metastasis from colorectal adenocarcinoma (Fig. 1). The patient was then treated by chemotherapy with irinotecan, calcium folinate and fluorouracil every 14 days for four cycles; however, the patient succumbed to progression of the disease.
case_images: PET, CT and fused images. The tonsil was swollen and the largest standardized uptake value was 8.08 (scale bar, 10 cm). PET, positron emission tomography; CT, computed tomography.
case_images: OL-07-01-0153-g01.jpg
case_images: PMC3861609_01_OL-07-01-0153-g01.jpg
case_images: f2-ol-07-01-0153
case_images: PET-CT revealed that the tonsil was swollen and the largest SUV was 8.08 (Fig. 2). Pathological examination was performed on the tonsil mass and the results indicated adenocarcinoma.