case_images: PMC10911662_01
case_images: Cervical-vaginal cytology, AC cells with eccentric hyperchromatic nuclei and cytoplasmic vacuolation are observed on an inflammatory background (20x PAP).
case_images: can-18-1671fig1.jpg
case_images: PMC10911662_01_can-18-1671fig1.jpg
case_images: figure1
case_images: The cells presented with a hypochromatic, eccentric nucleus and abundant vacuolated cytoplasm (Figure 1), and histology from a biopsy of the cervical tumour showed signet ring cell carcinoma.
case_images: Histological section of cervical tumour in which AC cells are seen on a background of mucin in a signet ring pattern with eccentric nucleus and vacuolated cytoplasm (20x HE).
case_images: can-18-1671fig2.jpg
case_images: PMC10911662_01_can-18-1671fig2.jpg
case_images: figure2
case_images: AC cells in a signet ring pattern with eccentric nuclei and vacuolated cytoplasm was observed on a mucin background (Figure 2). A p16 immunohistochemical study showed positive diffuse and intense expression in comparison to HPV (Figure 3).
case_images: Positive nuclear staining for p16 is observed in signet ring pattern AC cells (10x IHQ).
case_images: can-18-1671fig3.jpg
case_images: PMC10911662_01_can-18-1671fig3.jpg
case_images: figure3
case_images: AC cells in a signet ring pattern with eccentric nuclei and vacuolated cytoplasm was observed on a mucin background (Figure 2). A p16 immunohistochemical study showed positive diffuse and intense expression in comparison to HPV (Figure 3).