case_images: PMC9634216_01
case_images: Magnetic resonance imaging: T2 isointense to intermediate well-defined lesion in the right kidney.
case_images: JKCVHL-9-010-g001.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g001.jpg
case_images: F1
case_images: T2 isointense, to intermediate well-defined lesion with diffusion restriction (Figure 1). The nephrometry score was eight. The patient underwent right partial nephrectomy.
case_images: Macroscopy: Partial nephrectomy specimen showing well circumscribed grey white tumour with no haemorrhage or necrosis, limited to kidney. Adjacent kidney is unremarkable. Resected margins are free.
case_images: JKCVHL-9-010-g002.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g002.jpg
case_images: F2
case_images: No haemorrhage or necrosis was observed (Figure 2).
case_images: 100x magnification of haematoxylin and eosin stained section of renal tumour: Sheets and fascicles of bland-appearing spindle cells.
case_images: JKCVHL-9-010-g003.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g003.jpg
case_images: F3
case_images: Microscopic examination showed a neoplasm composed predominantly of bland-appearing spindle cells arranged in sheets and fascicles (Figure 3).
case_images: 200x magnification of haematoxylin and eosin stained section of renal tumour. It shows focal tubular structures lined by bland cuboidal cells, intermingled with spindle cells, in a mucinous stroma.
case_images: JKCVHL-9-010-g004.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g004.jpg
case_images: F4
case_images: The tumour was extensively sampled and embedded entirely which showed small foci of tubular structures lined by cuboidal cells intermingling with spindle cells (Figure 4).
case_images: 200x magnification of CK7 immunohistochemistry. Cuboidal cells lining tubules and spindle cells show positive reaction for CK7.
case_images: JKCVHL-9-010-g005.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g005.jpg
case_images: F5
case_images: Immunohistochemistry showed strong and diffuse positive reaction for pancytokeratin, CK7 (Figure 5), AMACR (Figure 6), PAX8, and vimentin, and negative reaction for SMA, S100, and CD34.
case_images: 200x magnification of AMACR immunohistochemistry. Cuboidal cells lining tubules and spindle cells show positive reaction for AMACR.
case_images: JKCVHL-9-010-g006.jpg
case_images: PMC9634216_01_JKCVHL-9-010-g006.jpg
case_images: F6
case_images: Immunohistochemistry showed strong and diffuse positive reaction for pancytokeratin, CK7 (Figure 5), AMACR (Figure 6), PAX8, and vimentin, and negative reaction for SMA, S100, and CD34.