case_images: PMC5075614_01
case_images: Core-needle biopsy of a right axillary lymph node revealed Reed-Sternberg cells (red circle) in a background of fibrosis and mixed inflammatory infiltrate.
case_images: CRIHEM2016-2103612.001.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.001.jpg
case_images: fig1
case_images: Core-needle biopsy of a right axillary lymph node revealed Reed-Sternberg cells in a background of fibrosis and mixed inflammatory infiltrate (Figure 1).
case_images: Bone marrow core showed foci of fibrosis with CD30-positive cells.
case_images: CRIHEM2016-2103612.002.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.002.jpg
case_images: fig2
case_images: Bone marrow core biopsy revealed foci of fibrosis with rare CD30-positive cells, consistent HL (Figure 2).
case_images: Hemophagocytosis consistent with HLH was noted in the bone aspirate smears.
case_images: CRIHEM2016-2103612.003.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.003.jpg
case_images: fig3
case_images: Additionally, hemophagocytosis was noted in the bone marrow aspirate smears (Figure 3).
case_images: Pretreatment maximum intensity projection (MIP) scan of the whole body showed increased extensive lymphadenopathy above and below the diaphragm with multiple osseous foci of increased FDG uptake.
case_images: CRIHEM2016-2103612.004.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.004.jpg
case_images: fig4
case_images: PET scan at Cycle 3/Day 1 showed interval resolution of FDG avid lymphadenopathy and bone lesions.
case_images: CRIHEM2016-2103612.005.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.005.jpg
case_images: fig5
case_images: Restaging MIP scan showed complete response to treatment.
case_images: CRIHEM2016-2103612.006.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.006.jpg
case_images: fig6
case_images: Posttreatment bone marrow biopsy showed mild hypocellularity with erythroid hyperplasia and dyspoiesis in the absence of Reed-Sternberg cells or hemophagocytosis.
case_images: CRIHEM2016-2103612.007.jpg
case_images: PMC5075614_01_CRIHEM2016-2103612.007.jpg
case_images: fig7