case_images: PMC10628483_01
case_images: Serum methotrexate levels for Case 1.
case_images: fonc-13-1237178-g003.jpg
case_images: PMC10628483_01_fonc-13-1237178-g003.jpg
case_images: f3
case_images: PMC10628483_02
case_images: Serum methotrexate levels for Case 2.
case_images: fonc-13-1237178-g004.jpg
case_images: PMC10628483_02_fonc-13-1237178-g004.jpg
case_images: f4
case_images: Although another HPLC assay was obtained at 6 days post-glucarpidase dosing demonstrating a high value at 0.48 mumol/L, his MTX levels as per the EMIT assay continued to steadily decline, returning to <0.10 mumol/L at 14 days following glucarpidase dosing ( Figure 4 ).