case_images: PMC10961413_01
case_images: Case 1 in our hospital. (A) Conventional two-dimensional ultrasonography revealed an ill-defined suborbicular lesion in the pancreatic tail (white row), with uneven hypoecho, of approximately 2.2 cm in size. (B) CEUS revealed hyperenhancement in the arterial phase. (C, D) Contrast-enhanced CT demonstrated a round iso-dense lesion (white rows) in the tail of the pancreas, with the mild enhancement in the arterial phase. (E) T2WI sequence revealed a well-defined round mass in the pancreatic tail, with high intensity. (F) Contrast-enhanced MRI showed slightly delayed enhancement (white row).
case_images: fonc-14-1310394-g001.jpg
case_images: PMC10961413_01_fonc-14-1310394-g001.jpg
case_images: f1
case_images: Conventional ultrasound (US) revealed a hypoechoic circular lesion in the tail of the pancreas, approximately 2.2 cm in size, with uniform internal echogenicity and clear borders, which means that no obvious Echo alteration can be observed and to distinguish the lesion with surrounding tissue is difficult (Figure 1A). CEUS suggested hyperenhancement in the arterial phase (Figure 1B) and mild hyperenhancement in the portal and delayed phases. Enhanced CT suggested a round, isointense lesion in the tail of the pancreas (Figures 1C, D). T1WI sequence and high signal in the T2WI sequence and a slight enhancement in the enhanced scan with late phase (Figures 1E, F). The patient also underwent positron emission computed tomography (PET) examination, and no obvious metabolic abnormality was found in the nodule of the pancreatic tail (Supplementary Figure S1).
case_images: PMC10961413_02
case_images: Case 2 in our hospital. (A) US demonstrated a round mass in the segment II of the liver near the dome of the diaphragm, with even slightly hyperecho, measuring about 1.9 cm x1.6 cm. (B) CEUS was performed and revealed hyperenhancement in the delayed phase (white rows). (C) The mass in the segment II of the liver (white rows) revealed low T2 signal. (D, E) Enhanced MR showed an arterial enhancement and had a gradual washout in the venous phases. (F) On DWI, no restricted diffusion was shown in the mass.
case_images: fonc-14-1310394-g002.jpg
case_images: PMC10961413_03_fonc-14-1310394-g002.jpg
case_images: f2
case_images: The baseline and imaging data for the three cases are shown in Table 1, and the pathological presentations are detailed in Supplementary Figures S2-S4.
case_images: PMC10961413_03
case_images: Case 2 in our hospital. (A) US demonstrated a round mass in the segment II of the liver near the dome of the diaphragm, with even slightly hyperecho, measuring about 1.9 cm x1.6 cm. (B) CEUS was performed and revealed hyperenhancement in the delayed phase (white rows). (C) The mass in the segment II of the liver (white rows) revealed low T2 signal. (D, E) Enhanced MR showed an arterial enhancement and had a gradual washout in the venous phases. (F) On DWI, no restricted diffusion was shown in the mass.
case_images: fonc-14-1310394-g002.jpg
case_images: PMC10961413_03_fonc-14-1310394-g002.jpg
case_images: f2
case_images: The baseline and imaging data for the three cases are shown in Table 1, and the pathological presentations are detailed in Supplementary Figures S2-S4.
case_images: Case 3 in our hospital. (A) CEUS suggested iso-enhancement in the portal phase (white rows). (B) Routine two-dimensional US showed an iso-echoic and round-like mass in the segment II of the liver. (C, D) The lesion (white rows) showed short T2 signal, and the enhancement scan suggested gradual signal attenuation after 5 min in the delayed phase.
case_images: fonc-14-1310394-g003.jpg
case_images: PMC10961413_03_fonc-14-1310394-g003.jpg
case_images: f3
case_images: CEUS suggested hyperenhancement in the arterial phase and iso-enhancement in the portal and delayed phases (Figures 3A, B). MRI and the enhancement scan are shown in Figures 3C, D. The baseline and imaging data for the three cases are shown in Table 1, and the pathological presentations are detailed in Supplementary Figures S2-S4.