case_images: PMC5436014_01
case_images: Preoperative neuroimaging of the patient showing an infiltrating right fronto-temporo-insular tumor with irregular contrast enhancement.
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case_images: Neuroimaging studies demonstrated an irregular space-occupying process consistent with a malignant glioma in the right fronto-temporo-insular region (Fig. 1).
case_images: Intraoperative view of the patient's cerebral surface with the naked eye (a), under blue light exposure (b), and by using IRT brain mapping (c).
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case_images: After the dura opening, the cerebral surface appeared seemingly normal (Fig. 2a). However, the ultraviolet light exposure revealed a moderate fluorescence in the region of the Silvian fissure (Fig. 2b), and the IRT observation demonstrated a significantly colder area (Deltat  1.01 C) in the limited field of the middle frontal gyrus, well corresponding to the epicenter of the lesion (Fig. 2c).
case_images: Conventional histological analysis of the lesion revealing prominent cellular polymorphism, microvascular proliferation, and pseudopalisading necroses. HE. x100.
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case_images: A partial excision of the lesion was performed, and the histological result was GBM (Fig. 3).