case_images: PMC11799706_01
case_images: (a-c) Preoperative magnetic resonance imaging (MRI) on initial admission shows a well-defined intradural intramedullary lesion in the region of thoracic vertebrae (Th)7-8. Lesions are hypointense on (a-1: sagittal view, a-2: axial view) T1-weighted imaging (WI) and hypointense on (b-1: sagittal view, b-2: axial view) T2-WI. The lesion appears enhanced following administration of (c-1: sagittal view, c-2: axial view) gadolinium (Gd). (d-1, d-2) Intraoperative findings reveal a soft, yellow lesion below the incision site. No adhesions are evident between the tumor and dura mater. (d-3) The tumor margin appears free of the spinal cord and is carefully dissected and removed. T, tumor.
case_images: SNI-16-28-g001.jpg
case_images: PMC11799706_01_SNI-16-28-g001.jpg
case_images: F1
case_images: T1-weighted imaging (WI) and hypointense on T2-WI, with uniform uptake on gadolinium (Gd)-enhanced T1-WI [Figures 1a-c]. The lesion was slightly eccentric and in contact with the soft tissue. T2-WI showed extensive hyperintensity in the spinal cord at the Th6-12 level, consistent with edematous changes. The tumor was carefully separated and removed [Figure 1d], and no spinal fusion was performed.
case_images: (a-1, a-2) a paraffin-embedded specimen from surgical biopsy shows round and polygonal cells with abundant granular eosinophilic cytoplasm and perivascular lymphocytic aggregates. Most nuclei are round to oval in appearance without evidence of cellular atypia and mitotic figures (hematoxylin and eosin staining). (b) This tumor shows slight positive staining for Ki-67 monoclonal antibody (MIB-1) (MIB-1 labeling index: 1.0%). Most tumor cells are immunoreactive for (c) S-100 and (d) SOX10 protein, but negative for (e) glial fibrillary acidic protein (GFAP) (3,3'diaminobenzidine staining). a-1, c, d, e: Magnification, x200; scale bar, 50 microm. a-2, b: Magnification, x400; scale bar, 100 microm.
case_images: SNI-16-28-g002.jpg
case_images: PMC11799706_01_SNI-16-28-g002.jpg
case_images: F2
case_images: GCT was therefore diagnosed [Figure 2].
case_images: Postoperative (a-1, b-1) T1-Gd and (a-2, b-2) T2-WI. a) One week after successful tumor resection. b) One year after surgery, no recurrences are apparent on MRI.
case_images: SNI-16-28-g003.jpg
case_images: PMC11799706_01_SNI-16-28-g003.jpg
case_images: F3
case_images: Postoperative MRI showed no residual tumor [Figure 3], and the perioperative course was uneventful.