case_images: PMC2782169_01
case_images: Gross photograph: finger tips show gangrenous changes.
case_images: jkms-20-677-g001.jpg
case_images: PMC2782169_01_jkms-20-677-g001.jpg
case_images: F1
case_images: Her fingertips were gangrenous (Fig. 1).
case_images: Lower extremity CT angiography; occlusions of right popliteal artery, right posterior tibial artery, right peroneal artery, left posterior tibial, left peroneal artery, left distal anterior tibial artery are seen.
case_images: jkms-20-677-g002.jpg
case_images: PMC2782169_01_jkms-20-677-g002.jpg
case_images: F2
case_images: It showed that the lower extremity arterial stenosis slightly progressed compared with previous study and upper extremity arteries below the wrist level had multiple stenosis (Fig. 2, 3).
case_images: Upper extremity CT angiography; multiple stenosis are seen in the upper extremity arteries below wrist level.
case_images: jkms-20-677-g003.jpg
case_images: PMC2782169_01_jkms-20-677-g003.jpg
case_images: F3
case_images: It showed that the lower extremity arterial stenosis slightly progressed compared with previous study and upper extremity arteries below the wrist level had multiple stenosis (Fig. 2, 3).
case_images: Skin biopsy: Immunohistochemistry show CD40L positive eosinophilic infiltration (x400).
case_images: jkms-20-677-g004.jpg
case_images: PMC2782169_01_jkms-20-677-g004.jpg
case_images: F4
case_images: Skin biopsy showed perivascular eosinophilic infiltration in the dermis and CD40 ligand (CD40L) positive eosinophilic infiltration (Fig. 4).
case_images: Serum TNF-alpha level compared with healthy controls and other hypereosinophilia without vasculitis.
case_images: jkms-20-677-g005.jpg
case_images: PMC2782169_01_jkms-20-677-g005.jpg
case_images: F5
case_images: The TNF-alpha was markedly increased more than that of several age-matched healthy persons and other hypereosinophilia patient without vasculitis (Fig. 5).