case_images: PMC10844421_01
case_images: (A) The patient's (a) electrocardiogram at the time of hospital admission and (b) the electrocardiogram during the follow-up examination two months later. (B) The results of the patient's first coronary angiography are as follows: (a) The left anterior descending artery (LAD) mid-segment with approximately 95% stenosis, (b) The left circumflex artery (LCX) mid-distal segment with approximately 70% stenosis, (c) The dominant second obtuse marginal branch (OM2) proximal segment with approximately 90% stenosis, and (d) The right coronary artery (RCA) mid-segment with approximately 90% stenosis. The patient underwent the first-stage percutaneous coronary intervention (PCI) in the (e) LAD, (f) LCX, and OM2. A second-stage PCI was performed 7 days later, involving (g) the RCA mid-segment with approximately 90% stenosis, and (h) stents were implanted. The areas indicated by the arrows in the figure represent vascular stenosis or locations where stents have been implanted.
case_images: fcvm-11-1332307-g001.jpg
case_images: PMC10844421_01_fcvm-11-1332307-g001.jpg
case_images: F1
case_images: The electrocardiogram revealed ST-segment depression exceeding 0.05mv in leads II, V3-V6, accompanied by T-wave inversion (Figure 1A). He underwent elective coronary angiography, which unveiled multi-vessel coronary artery stenosis by physician visual assessment (Figure 1B). A second-stage PCI for the RCA was performed 7 days later (Figure 1B). Two months later, the patient's ECG was normal (Figure 1A), cardiac injury markers and thyroid function were normal, and there was some improvement in dyslipidemia (low-density lipoprotein 1.36 mmol/L, high-density lipoprotein 1.06 mmol/L, total cholesterol 2.87 mmol/L, triglycerides 2.15 mmol/L).
case_images: 68Ga-FAPI-04 PET/CT myocardial imaging. A. Examination results one day after postoperative PCI. B. Follow-up examination results after two months.
case_images: fcvm-11-1332307-g002.jpg
case_images: PMC10844421_01_fcvm-11-1332307-g002.jpg
case_images: F2
case_images: To evaluate the patient's myocardial fibrosis, a 68Ga-FAPI-04 PET/CT examination was conducted the day following the first stage PCI (Figure 2A). A follow-up 68Ga-FAPI PET/CT examination (Figure 2B) revealed a slight increase in FAP expression in a smaller localized area of the left ventricular apex, with an SUVmax of approximately 1.8.