case_images: PMC9207404_01
case_images: Case 1. Magnetic resonance image of a 4.0x2.8-cm solid mass in the fourth ventricle, with supratentorial hydrocephalus. (A) T1-weighted image showing low signal. (B) T2-weighted image showing low signal. (C) Homogeneous enhancement on contrast-enhanced T1-weighted images. (D) Postoperative magnetic resonance image showing no residual lesion, and obstructive hydrocephalus is relieved. Pathological microscopic examination shows diffuse large B-cell infiltration [(E) hematoxylin and eosin, 200x magnification], including CD20- [(F), 400x magnification], LCA- [(G), 400x magnification], and MUM-positive [(H), 400x magnification] lesions.
case_images: fneur-13-920505-g0002.jpg
case_images: PMC9207404_01_fneur-13-920505-g0002.jpg
case_images: F2
case_images: Brain MRI revealed a 4.0x2.8-cm solid mass in the fourth ventricle (Figure 2), which was considered a medulloblastoma or solid hemangioblastoma. Histopathological examination revealed diffuse large B-cell infiltration (Figure 2E), with positive immunochemical staining for CD20, LCA, and MUM (Figures 2F-H, respectively).
case_images: PMC9207404_02
case_images: Case 2. (A,B) Contrast-enhanced T1-weighted axial images show nodular bead-like lesions in the right and fourth ventricles. (C) Sagittal magnetic resonance images showing multiple lesions occupying the midbrain aqueduct and fourth ventricle. (D) Postoperative computed tomography shows edema of brain tissue and no bleeding in the operative cavity.
case_images: fneur-13-920505-g0003.jpg
case_images: PMC9207404_02_fneur-13-920505-g0003.jpg
case_images: F3
case_images: Magnetic resonance imaging (MRI) examination revealed multiple lesions in the right lateral ventricle, middle cerebral aqueduct, and fourth ventricle, some of which were cluster-like, accompanied by hydrocephalus, with avid enhancement (Figure 3).
case_images: PMC9207404_03
case_images: Case 8. Axial magnetic resonance image showing bilateral and fourth ventricle lesions, diffuse growth along the choroid plexus and ventricle wall, low signal on T1- and T2-weighted images (A,B), and homogeneous enhancement on contrast-enhanced T1-weighted images (C,D).
case_images: fneur-13-920505-g0004.jpg
case_images: PMC9207404_03_fneur-13-920505-g0004.jpg
case_images: F4
case_images: MRI examination revealed lesions in bilateral ventricles and the fourth ventricle (Figure 4), which could not be diagnosed clearly before surgery.