case_images: PMC10915652_01
case_images: Computed tomography images showing the heterogeneously enhancing left renal mass involving the left renal vein and IVC and abutting the aorta. (A) Cross-sectional image and (B) Sagittal image. (T - Tumor), arrow pointing to the inferior vena cava (IVC) thrombus.
case_images: JKCVHL-11-033-g001.jpg
case_images: PMC10915652_01_JKCVHL-11-033-g001.jpg
case_images: F1
case_images: Contrast enhanced computed tomography (CECT) abdomen revealed a 11-cm partly cystic, heterogeneously enhancing left renal mass abutting the aorta with a thrombus in the left renal vein extending to the inferior vena cava (IVC) (Figure 1A,B).
case_images: (A-C) Sheets of round cells with moderate cytoplasm and hyperchromatic nuclei with interspersed vascular spaces. H&E 200x, (D) Tumor cells express vimentin. DAB 400x, (E) Tumor cells express smooth muscle actin. DAB 400X, (F) Tumor cells show high proliferative activity with Ki67. DAB 400x DAB - Diaminobenzene.
case_images: JKCVHL-11-033-g002.jpg
case_images: PMC10915652_01_JKCVHL-11-033-g002.jpg
case_images: F2
case_images: This showed fibroconnective tissue infiltrated by sheets of atypical cells showing moderate cytoplasm, hyperchromatic pleomorphic nuclei with inconspicuous nucleoli, suggesting a poorly differentiated malignant tumor (Figure 2A,C). Immunohistochemistry was positive for vimentin, smooth muscle actin (SMA), keratin, caldesmon and weakly positive for calponin, with 40% Ki 67 positivity, suggesting a diagnosis of malignant glomus tumor (Figure 2D,F).