case_images: PMC10711588_01
case_images: Multimodal imaging of both eyes. (a) Color fundus photograph (CFP) of RE showing hypopigmented, wedge-like lesion on the superior temporal juxtafoveal area (b). CFP of LE showing no apparent pathology. (c and d) Infrared (IR) reflectance images revealed hyporeflective, well-circumscribed parafoveal lesion corresponding to the lesion area in RE (c) and LE (d). (e and f) Fundus autofluorescence (FAF) of right (f) showed subtle macular hypoautofluorescence in the lesion area, and FAF of LE (e) showed no significant finding. (g and h) Spectral-domain optical coherence tomography (OCT) RE (g) and LE (h) showing focal hyperreflectivity in the outer nuclear layer (ONL) with disruption on ellipsoid zone and retinal pigment epithelium (RPE) layers. (i) Multicolor imaging of RE showing hyporeflective circumscribed wedge-like lesion on the superior temporal juxtafoveal area (j) Multicolor fundus imaging of LE showing hyporeflective small wedge-like lesion on the inferior nasal juxtafoveal area.
case_images: BEJ-8-293-g001.jpg
case_images: PMC10711588_01_BEJ-8-293-g001.jpg
case_images: F1
case_images: Fundus examination revealed a hypopigmented, wedge-like lesion on the superior temporal juxtafoveal area in the right eye (RE) (Fig. 1a), while no significant finding was found in the left eye (LE) (Fig. 1b). Infrared reflectance images revealed bilateral hyporeflective, well-circumscribed lesions in parafoveal regions of the macula (Figs. 1c and d). Spectral domain optical coherence tomography (SD-OCT) (Heidelberg Spectralis HRA + OCT MultiColor, Germany) scans over the corresponding area detected focal hyperreflectivity in the outer nuclear layer (ONL) with disruption on the ellipsoid zone (EZ) and retinal pigment epithelium layers (Figs. 1g and h). Fundus autofluorescence imaging at presentation showed subtle macular hypoautofluorescence on the lesion area in RE and no significant finding in LE (Figs. 1e and f). Multicolor imaging showed a hyporeflective parafoveal wedge-like lesion in RE corresponding to the lesion area and a small parafoveal well-circumscribed lesion in LE corresponding to the lesion area (Figs. 1i and j).
case_images: Paracentral scotomata in the visual field for the right eye.
case_images: BEJ-8-293-g002.jpg
case_images: PMC10711588_01_BEJ-8-293-g002.jpg
case_images: F2
case_images: Humphrey visual field 24-2 testing confirmed bilateral paracentral scotomata (Figs. 2 and 3).
case_images: Paracentral scotomata in the visual field for left eye despite high fixation losses.
case_images: BEJ-8-293-g003.jpg
case_images: PMC10711588_01_BEJ-8-293-g003.jpg
case_images: F3
case_images: Humphrey visual field 24-2 testing confirmed bilateral paracentral scotomata (Figs. 2 and 3).