case_images: PMC4609797_01
case_images: PMC4609797_02
case_images: Right eye before therapy.
case_images: CRIOPM2015-181267.003.jpg
case_images: PMC4609797_02_CRIOPM2015-181267.003.jpg
case_images: fig3
case_images: BCVA was 20/32 in right eye and 20/20 in left eye; slit-lamp examination showed wrinkling of the conjunctiva and keratinization in both eyes and sterile and peripheral ulcer in right eye (Figures 3 and 4).
case_images: Left eye before therapy.
case_images: CRIOPM2015-181267.004.jpg
case_images: PMC4609797_02_CRIOPM2015-181267.004.jpg
case_images: fig4
case_images: BCVA was 20/32 in right eye and 20/20 in left eye; slit-lamp examination showed wrinkling of the conjunctiva and keratinization in both eyes and sterile and peripheral ulcer in right eye (Figures 3 and 4).
case_images: Right eye after therapy.
case_images: CRIOPM2015-181267.005.jpg
case_images: PMC4609797_02_CRIOPM2015-181267.005.jpg
case_images: fig5
case_images: The conjunctiva and the cornea improved and, after 7-8 weeks, the cornea ulcer in right eye and the conjunctiva keratinization disappeared and a complete resolution of clinical manifestations was observed (Figures 5 and 6).
case_images: Left eye after therapy.
case_images: CRIOPM2015-181267.006.jpg
case_images: PMC4609797_02_CRIOPM2015-181267.006.jpg
case_images: fig6
case_images: The conjunctiva and the cornea improved and, after 7-8 weeks, the cornea ulcer in right eye and the conjunctiva keratinization disappeared and a complete resolution of clinical manifestations was observed (Figures 5 and 6).
case_images: PMC4609797_03
case_images: Right eye before therapy.
case_images: CRIOPM2015-181267.007.jpg
case_images: PMC4609797_03_CRIOPM2015-181267.007.jpg
case_images: fig7
case_images: At slit-lamp examination the patient presented keratinization of the conjunctiva and shortening of the lower conjunctival fornix in both eyes, partial corneal keratinization in the left eye (Figures 7(a), 7(b), and 8), and glaucomatous optic neuropathy in both eyes.
case_images: Right eye after therapy.
case_images: CRIOPM2015-181267.009.jpg
case_images: PMC4609797_03_CRIOPM2015-181267.009.jpg
case_images: fig9
case_images: The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.
case_images: Left eye after 3 weeks of therapy.
case_images: CRIOPM2015-181267.010.jpg
case_images: PMC4609797_03_CRIOPM2015-181267.010.jpg
case_images: fig10
case_images: The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.
case_images: Left eye after 8 weeks of therapy.
case_images: CRIOPM2015-181267.011.jpg
case_images: PMC4609797_03_CRIOPM2015-181267.011.jpg
case_images: fig11
case_images: The keratinization of the cornea and conjunctiva improved in both eyes (Figures 9, 10, and 11), but systemic clinical condition of this critical patient worsened after 3 months and she died.