case_images: PMC3805180_01
case_images: High forehead with flat supraorbital ridges and widely spaced eyes.
case_images: tacg-6-087Fig1.jpg
case_images: PMC3805180_01_tacg-6-087Fig1.jpg
case_images: f1-tacg-6-087
case_images: She had sparse lateral eyebrows, long eyelashes, wide-set eyes (telecanthus) with hypertelorism, low-set ears, a broad nasal bridge with a prominent tip, micrognathia, a thin upper lip, a high-arched palate, dental caries, a sacral dimple, and eczematous skin changes on the extremities, mainly on the flexural areas (Figures 1 and 2).
case_images: Prominent nasal bridge and sparse eyebrows.
case_images: tacg-6-087Fig2.jpg
case_images: PMC3805180_01_tacg-6-087Fig2.jpg
case_images: f2-tacg-6-087
case_images: She had sparse lateral eyebrows, long eyelashes, wide-set eyes (telecanthus) with hypertelorism, low-set ears, a broad nasal bridge with a prominent tip, micrognathia, a thin upper lip, a high-arched palate, dental caries, a sacral dimple, and eczematous skin changes on the extremities, mainly on the flexural areas (Figures 1 and 2).
case_images: Prematurely aged appearance of the proband when she smiles.
case_images: tacg-6-087Fig3.jpg
case_images: PMC3805180_01_tacg-6-087Fig3.jpg
case_images: f3-tacg-6-087
case_images: When she smiled, her facial skin wrinkled and she looked like a prematurely aged girl (Figure 3).