case_images: PMC4935008_01
case_images: Cervical lymph node biopsy.. Notes: (A) Lymph node with geographic necrosis surrounded by histiocytes (hematoxylin-eosin stain, x10 magnification). (B) Geographic necrosis and cellular detritus without the presence of polymorphonuclear neutrophils or histiocytes (hematoxylin-eosin stain, x40 magnification). (C and D) Positive immunostaining in histiocytes with CD68 (hematoxylin-eosin stain, x10 and x40 magnifications). (E) Immunostaining with CD20 antibody (hematoxylin-eosin stain, x10 magnification). (F) Negative immunostaining with CD1a antibody (hematoxylin-eosin stain, x40 magnification).
case_images: imcrj-9-163Fig1.jpg
case_images: PMC4935008_01_imcrj-9-163Fig1.jpg
case_images: f1-imcrj-9-163
case_images: Owing to the nonspecific findings of the first lymph node sampling, it was decided to perform a second biopsy guided by ultrasound to select tissue with less necrosis (Figure 1).