case_images: PMC11809598_01
case_images: CT chest with contrast showing the osteoblastic lesions in the ribs (a) and vertebrae (b) (arrows). CT: computed tomography.
case_images: jh-14-032-g001.jpg
case_images: PMC11809598_01_jh-14-032-g001.jpg
case_images: F1
case_images: Computed tomography (CT) chest with contrast showed diffuse osteoblastic lesions in the ribs and vertebrae (Fig. 1a, b), and CT abdomen and pelvis with contrast revealed diffuse osteoblastic lesions in the pelvic bones (Fig. 2), hepatosplenomegaly and portal vein thrombosis (Fig. 3).
case_images: CT abdomen and pelvis with contrast showing hepatosplenomegaly and dilated portal vein (arrows). CT: computed tomography.
case_images: jh-14-032-g003.jpg
case_images: PMC11809598_01_jh-14-032-g003.jpg
case_images: F3
case_images: Computed tomography (CT) chest with contrast showed diffuse osteoblastic lesions in the ribs and vertebrae (Fig. 1a, b), and CT abdomen and pelvis with contrast revealed diffuse osteoblastic lesions in the pelvic bones (Fig. 2), hepatosplenomegaly and portal vein thrombosis (Fig. 3).
case_images: Bone marrow biopsy showing atypical mast cells (arrows).
case_images: jh-14-032-g004.jpg
case_images: PMC11809598_01_jh-14-032-g004.jpg
case_images: F4
case_images: The bone marrow biopsy showed a hypercellular marrow for age with diffuse and patchy infiltration by large cells with fine basophilic granules, and microvacuoles most compatible with atypical mast cells (Fig. 4), with increased CD117 (Fig. 5) and tryptase positivity consistent with acute MCL.
case_images: Left ilium bone biopsy showing atypical mast cells.
case_images: jh-14-032-g006.jpg
case_images: PMC11809598_01_jh-14-032-g006.jpg
case_images: F6
case_images: The left ilium bone biopsy showed dense areas of atypical mast cell infiltrates (Fig. 6) and atypical mononuclear cells positive for CD117 (Fig. 7) and tryptase, compatible with