case_images: PMC4763582_01
case_images: Multiple pink papules and sun-damaged skin of the right cheek
case_images: IDOJ-7-49-g001.jpg
case_images: PMC4763582_01_IDOJ-7-49-g001.jpg
case_images: F1
case_images: A 77-year-old man presented for routine skin exam and was noted to have slightly elevated pink papules on both his cheeks [Figure 1].
case_images: (a) Dense diffuse lymphocytic infiltrate with a Grenz zone. Hematoxylin and eosin (H and E) stained sections, x40; (b) Monomorphic medium-sized atypical lymphocytes, with blast-like nuclei. H and E stained sections, x400
case_images: IDOJ-7-49-g002.jpg
case_images: PMC4763582_01_IDOJ-7-49-g002.jpg
case_images: F2
case_images: A shave biopsy after revealed a dense nodular and diffuse infiltrate of atypical medium-sized lymphocytes [Figure 2A and B].
case_images: Immunohistochemical profile of the mantle cell lymphoma, Case 1 x100
case_images: IDOJ-7-49-g003.jpg
case_images: PMC4763582_01_IDOJ-7-49-g003.jpg
case_images: F3
case_images: CD5 stained a few reactive T cells, but the tumor cells were negative [Figure 3].
case_images: PMC4763582_02
case_images: (a) Diffuse lymphocytic infiltrate, H and E stained sections, x100. (b) Atypical medium-sized to large lymphocytes with multiple mitotic figures, H and E stained sections, x600
case_images: IDOJ-7-49-g004.jpg
case_images: PMC4763582_02_IDOJ-7-49-g004.jpg
case_images: F4
case_images: A punch biopsy showed a diffuse lymphocytic infiltrate in the dermis [Figure 4].
case_images: Immunohistochemical profile of the mantle cell lymphoma, Case 2. x100
case_images: IDOJ-7-49-g005.jpg
case_images: PMC4763582_02_IDOJ-7-49-g005.jpg
case_images: F5
case_images: The atypical lymphocytes expressed cyclin D-1, CD5, CD45, CD79a, PAX5, and CD20 [Figure 5].