case_images: PMC3843912_01
case_images: Pustular palmar lesions, associated with erythema and desquamation.
case_images: cde-0005-0326-g01.jpg
case_images: PMC3843912_01_cde-0005-0326-g01.jpg
case_images: F1
case_images: Dermatology Ambulatory as an emergency case due to complaints of sudden onset of pustular lesions in the palms and soles (fig. 1, fig. 2), and erythematous-desquamating plaques with pustules in the limbs, chest and dorsum (fig. 3). During anamnesis, we found that the patient had recently begun the use of golimumab, a
case_images: Pustules in the center of erythematous-desquamative lesions of the lower limbs.
case_images: cde-0005-0326-g03.jpg
case_images: PMC3843912_01_cde-0005-0326-g03.jpg
case_images: F3
case_images: Dermatology Ambulatory as an emergency case due to complaints of sudden onset of pustular lesions in the palms and soles (fig. 1, fig. 2), and erythematous-desquamating plaques with pustules in the limbs, chest and dorsum (fig. 3). During anamnesis, we found that the patient had recently begun the use of golimumab, a
case_images: Epidermis with acanthosis and exuberant exocytosis of neutrophils, which in segment configure Kogoj's spongiform pustule; note also dilation of the capillaries of the papillary dermis. HE. x10.
case_images: cde-0005-0326-g04.jpg
case_images: PMC3843912_01_cde-0005-0326-g04.jpg
case_images: F4
case_images: Histopathology showed abundant neutrophilic infiltrate (Munro's abscess), acanthosis, presence of Kogoj's spongiform pustule, and dilation of papillary dermal capillaries (fig. 4, fig. 5).