case_images: PMC10519172_01
case_images: Gross appearance of the right ovarian mass.
case_images: IMCRJ-16-571-g0001.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0001.jpg
case_images: f0001
case_images: Up on gross examination, the right ovary was massively enlarged with an irregular outer surface measuring 15x12x8 cm with a cut surface of gray-white solid having multiple cystic spaces that are filled with brownish viscous fluid (Figures 1 and 2). Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: Cut surface of the right ovarian mass.
case_images: IMCRJ-16-571-g0002.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0002.jpg
case_images: f0002
case_images: Up on gross examination, the right ovary was massively enlarged with an irregular outer surface measuring 15x12x8 cm with a cut surface of gray-white solid having multiple cystic spaces that are filled with brownish viscous fluid (Figures 1 and 2). Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: (A) Gross appearance of the appendix with a nodule over its tip. (B) Cut surface appearance of the appendix.
case_images: IMCRJ-16-571-g0003.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0003.jpg
case_images: f0003
case_images: The appendix had a nodular mass over its tip that measured 5x4x2 cm with a cut surface of tan white having multiple small nodularities and brownish foci (Figure 3). Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: (A) Low power view (40x) from the right ovary showing predominantly follicular growth pattern. (B) Medium power view (200x) from the right ovary showing predominantly follicular growth pattern.
case_images: IMCRJ-16-571-g0004.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0004.jpg
case_images: f0004
case_images: Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: High power view (600x) showing classic cytomorphologic features of PTC with washed out chromatin, nuclear elongation, grooving and pseudo inclusions (arrows).
case_images: IMCRJ-16-571-g0005.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0005.jpg
case_images: f0005
case_images: Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: Microscopic view of appendiceal mass with apparent metastatic thyroid tissue that has pushed the appendiceal mucosa (arrow).
case_images: IMCRJ-16-571-g0006.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0006.jpg
case_images: f0006
case_images: Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.
case_images: Inset view of the appendix (red arrow) and the periphery of the tumor deposit (blue arrow).
case_images: IMCRJ-16-571-g0007.jpg
case_images: PMC10519172_01_IMCRJ-16-571-g0007.jpg
case_images: f0007
case_images: Despite the fact that we sampled the tissue extensively, we did not find admixed teratomatous component (Figures 4-7 and Supplementary Figures 1-4) With these histomorphologic features, the case was signed out as malignant struma ovarii, a follicular variant of papillary thyroid carcinoma (FVPTC) with secondary deposits on the appendix.