case_images: PMC5698793_01
case_images: Colonoscopy showing severe ileal serpiginous ulceration and diffuse ileitis (Rutgeerts classification i4) before starting vedolizumab and ustekinumab therapy.
case_images: CRIM2017-5264216.001.jpg
case_images: PMC5698793_01_CRIM2017-5264216.001.jpg
case_images: fig1
case_images: Crohn's symptoms and iron deficiency anemia after receiving a retrial of infliximab with the addition of methotrexate combination therapy. Colonoscopy showed ongoing deep serpiginous ileal ulcers, colonic aphthous ulceration, and worsening deep rectal ulceration (Figure 1).
case_images: Colonoscopy showing ileal mucosal healing 6 months after starting vedolizumab and ustekinumab therapy.
case_images: CRIM2017-5264216.002.jpg
case_images: PMC5698793_01_CRIM2017-5264216.002.jpg
case_images: fig2
case_images: Colonoscopy 6 months after dual biologic therapy showed mucosal healing of the ileum and colon (Figure 2), which is the first time the patient has had mucosal healing since diagnosis.