case_images: PMC3518095_01
case_images: Barrett's esophagus with nodularity and high-grade dysplasia (HGD) visualized with HD-WLE (a), i-scan mode 1 (b) and (c), and i-scan mode 3 (d). Histopathology of EMR specimen showing Barrett's esophagus with HGD, H&E stain, and 400x magnification (e).
case_images: DTE2012-193570.002.jpg
case_images: PMC3518095_01_DTE2012-193570.002.jpg
case_images: fig2
case_images: EGD with HD-WLE demonstrated 2 cm of Barrett's mucosa (Figure 2(a)). With i-scan activated an erythematous area of nodularity within the Barrett's was better defined (Figures 2(b), 2(c), and 2(d)). Histopathology of the EMR specimen demonstrated high-grade dysplasia (HGD) within the central nodule and surrounding low-grade dysplasia (Figure 2(e)).
case_images: PMC3518095_02
case_images: PMC3518095_03
case_images: PMC3518095_04
case_images: Raised nodule of adenocarcinoma within a segment of Barrett's esophagus as seen with HD-WLE (a), i-scan mode 1 (b), i-scan mode 2 (c), and i-scan mode 3 (d).
case_images: DTE2012-193570.003.jpg
case_images: PMC3518095_04_DTE2012-193570.003.jpg
case_images: fig3
case_images: On EGD the patient had 7 cm segment of Barrett's esophagus, with a single are of nodularity as seen on HD-WLE endoscopy image (Figure 3(a)). i-scan Modes 1, 2, and 3 (Figures 3(b), 3(c), and 3(d)) demonstrated the surface enhancement and margins of the nodule, thus targeting EMR.
case_images: PMC3518095_05
case_images: PMC3518095_06
case_images: Gastric mucosa associated lymphoid tissue (MALT) lymphoma visualized with HD-WLE (a), i-scan mode 1 (b), and i-scan mode 3 (c). Histopathology showing MALT lymphoma, H&E stain, and 400x magnification (d).
case_images: DTE2012-193570.004.jpg
case_images: PMC3518095_06_DTE2012-193570.004.jpg
case_images: fig4
case_images: On EGD, in the body and fundus of the stomach, WLE demonstrated pale, atrophic-appearing mucosa that could be consistent with gastritis or gastropathy (Figure 4(a)). i-scan was activated and demonstrated a patch of pale yellow mucosa with surrounding nodular, edematous gastric folds (Figures 4(b) and 4(c)). The histopathology demonstrated low-grade mucosa associated lymphoid tissue (MALT) lymphoma (Figure 4(d)).
case_images: PMC3518095_07
case_images: PMC3518095_08
case_images: PMC3518095_09
case_images: PMC3518095_10
case_images: PMC3518095_11
case_images: PMC3518095_12
case_images: Sessile serrated polyp visualized under HD-WLE (a) and with i-scan mode 2 (b).
case_images: DTE2012-193570.005.jpg
case_images: PMC3518095_12_DTE2012-193570.005.jpg
case_images: fig5
case_images: A minimally erythematous flat mucosal abnormality was noted in the ascending colon with WLE (Figure 5(a)). Further characterization with i-scan mode 2 showed a 7 mm polyp that was removed with hot snare (Figure 5(b)).
case_images: PMC3518095_13
case_images: PMC3518095_14
case_images: PMC3518095_15
case_images: Large rectal polyp with focus of adenocarcinoma, visualized with HD-WLE (a), i-scan mode 1 (b), i-scan mode 2 (c), and i-scan mode 3 (d).
case_images: DTE2012-193570.006.jpg
case_images: PMC3518095_15_DTE2012-193570.006.jpg
case_images: fig6
case_images: Upon retroflexion in the rectum, another 2 cm sessile polyp was seen (Figure 6(a)). i-scan modes 1, 2, and 3 were turned on and more clearly visualized the extent and borders of this large polyp and defined the lesion edges (Figures 6(b), 6(c), and 6(d)).
case_images: PMC3518095_16
case_images: PMC3518095_17