case_images: PMC11066659_01
case_images: The patient develops a blister-like rash all over the body with widespread itching.
case_images: CCID-17-941-g0001.jpg
case_images: PMC11066659_01_CCID-17-941-g0001.jpg
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case_images: Additionally, over 20 dispersed blisters, ranging from mung bean to soybean in size, were observed across the bilateral forearms, trunk, and left lower limb, as depicted in Figure 1.
case_images: Histopathologic images of the patient's skin lesions (HE x 100). (a) Microscopic evaluation revealed the presence of blister-like formations beneath the stratum corneum, characterized by the presence of loosened spinous cells. There was a mild disintegration observed at the base of these structures, coupled with a discernible lymphocytic infiltration encircling the periphery. (b) Disintegration of blisters and balloon-like degeneration of cells with a little inflammatory cell infiltration are seen under the stratum corneum. The arrows in the figure indicate cellular balloon-like degeneration.
case_images: CCID-17-941-g0002.jpg
case_images: PMC11066659_01_CCID-17-941-g0002.jpg
case_images: f0002
case_images: AIDS virus returned negative results. As shown in Figure 2, a biopsy conducted on the abdominal lesions revealed intraepidermal vesicle formation.