case_images: PMC5646291_01
case_images: (a and c) Large atypical lymphoid cells with one to more nuclei, prominent nucleoli, and abundant cytoplasm consistent with RS cells and Hodgkin cells on the hematoxylin and eosin stain. (b and d) The large atypical cells are negative for PAX5 expression.
case_images: CRIHEM2017-7531729.001.jpg
case_images: PMC5646291_02_CRIHEM2017-7531729.001.jpg
case_images: fig1
case_images: The majority of the large cells were mononucleated cells with prominent large cherry red nucleoli and moderate to abundant eosinophilic cytoplasm, consistent with Hodgkin cells (Figure 1(c)). These large cells were positive for CD30, CD15 (subset), CD79a (small subset), and MUM1 but were negative for CD20, CD45, OCT2, PAX5 (Figure 1(d)), CD2, CD3, CD4, CD5, CD7 CD8, granzyme-B, perforin, and ALK1.
case_images: PMC5646291_02
case_images: (a and c) Large atypical lymphoid cells with one to more nuclei, prominent nucleoli, and abundant cytoplasm consistent with RS cells and Hodgkin cells on the hematoxylin and eosin stain. (b and d) The large atypical cells are negative for PAX5 expression.
case_images: CRIHEM2017-7531729.001.jpg
case_images: PMC5646291_02_CRIHEM2017-7531729.001.jpg
case_images: fig1
case_images: The majority of the large cells were mononucleated cells with prominent large cherry red nucleoli and moderate to abundant eosinophilic cytoplasm, consistent with Hodgkin cells (Figure 1(c)). These large cells were positive for CD30, CD15 (subset), CD79a (small subset), and MUM1 but were negative for CD20, CD45, OCT2, PAX5 (Figure 1(d)), CD2, CD3, CD4, CD5, CD7 CD8, granzyme-B, perforin, and ALK1.