case_images: PMC4350195_01
case_images: Fluid-attenuated inversion recovery (FLAIR) (a) and T2-weighted (b) brain magnetic resonance imaging (MRI) showing bilateral, symmetric, confluent areas of high signal intensity in the periventricular, subcortical white matter, corona radiata, centrum semiovale and globus pallidus. Diffusionweighted MRI (c) and the corresponding apparent diffusion coefficient map (d) showing restricted water diffusion at the periventricular white matter, corona radiata and centrum semiovale. Brain single-photon emission computed tomography (e) showing inhomogeneous perfusion in the cerebral cortex, with relative decreased uptake in bilateral frontal regions
case_images: AIAN-18-108-g001.jpg
case_images: PMC4350195_01_AIAN-18-108-g001.jpg
case_images: F1
case_images: T2-weighted and fluid-attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) showed bilateral, symmetric, confluent areas of high signal intensity in the periventricular, subcortical white matter, corona radiata, centrum semiovale and globus pallidus [Figure 1a and b]. Diffusion-weighted MRI and the corresponding apparent diffusion coefficient map showed restricted water diffusion at the periventricular white matter, corona radiata, and centrum semiovale, suggesting cytotoxic edema [Figure 1c and d]. Brain single-photon emission computed tomography (SPECT) with technetium-99 ethylene cysteine dimer showed inhomogeneous perfusion in the cerebral cortex, with decreased uptake in bilateral frontal regions [Figure 1e].
case_images: Follow-up brain MRI showing more cortical atrophy and prominent hyperintensity of the bilateral periventricular white matter seen on FLAIR (a) and T2-weighted image (b)
case_images: AIAN-18-108-g002.jpg
case_images: PMC4350195_01_AIAN-18-108-g002.jpg
case_images: F2
case_images: Follow-up brain MRI 8 months later showed more cortical atrophy and prominent hyperintensity of the bilateral periventricular white matter seen on FLAIR and T2-weighted image [Figure 2a and b].