case_images: PMC11794821_01
case_images: (A) Gastroscopy revealed localized esophageal erosions and gastric nodules and ulcers at diagnosis. (B) Gastroscopy revealed that the gastric nodules and ulcers disappeared after 6 weeks of induction chemotherapy; however, esophageal erosions still existed.
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case_images: We could still clearly observe gastric nodules and ulcers ( Figure 1A ). After 6 weeks of induction chemotherapy, gastroscopy revealed that the number of lesions in the stomach and esophagus had significantly reduced ( Figure 1B ).
case_images: (A) Elevated FDG metabolism was detected in the gastric body, gastric antrum, nasopharynx, left submandibular gland, lymph nodes, thymus, and liver by whole-body FDG PET/CT examination. (B) Pathological biopsies revealed atypical cells in the gastric antrum expressing CD 1a, S-100, and Langerin.
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case_images: Figure 2B ). Furthermore, we detected 38 LCH-related genes, including KRAS, ARAF, ERBB2, Whole-body FDG PET/CT revealed elevated FDG metabolism in the gastric body, gastric antrum, nasopharynx, left submandibular gland, lymph nodes, thymus, and liver ( Figure 2A ).