case_images: PMC6595665_01
case_images: (a) Transversal image of the CT scan showing a large, multilobulated, hepatic mass. (b) Ultrasonographic appearance of the liver tumour. (c) Sagittal image of the thorax and abdomen showing heterogeneous contrast enhancement of the liver
case_images: 10.1177_2055116919856129-fig1.jpg
case_images: PMC6595665_01_10.1177_2055116919856129-fig1.jpg
case_images: fig1-2055116919856129
case_images: CT of the head, thorax and abdomen revealed a 15 cm maximum diameter, multilobular cystic mass arising from the caudal left liver lobe (Figure 1).
case_images: (a) Micrograph of the hepatocellular carcinoma on the left, with normal congested hepatic parenchyma on the right. Haematoxylin and eosin, x 200. (b) Micrograph showing the negative immunostaining for insulin growth factor 2 (IGF-2). Inset: positive IGF-2 staining in the normal liver
case_images: 10.1177_2055116919856129-fig2.jpg
case_images: PMC6595665_01_10.1177_2055116919856129-fig2.jpg
case_images: fig2-2055116919856129
case_images: IGF-2 immunohistochemistry on sections from formalin-fixed, paraffin-embedded liver biopsies using an IGF-2 antibody (1:200; ab9574 [Abcam]), and feline colonic tissue as a positive control, revealed scattered positive staining in normal hepatocytes but not in neoplastic cells (Figure 2).