case_images: PMC11249548_01
case_images: Computer tomography (CT) scan dated September 2021, before patient started durvalumab. a, b Emphysema and infection in the right lung. c A tumor in the upper lobe of the left lung (red arrow). g, h, i Multiple lymph node metastasis in the mediastinum and bilateral hilum. CT scan dated October 2021, after patient started durvalumab. d, e New interstitial inflammatory lesions in a large area of the right lung (green arrows). f The tumor in the left lung was smaller after treatment start. j, k, l Multiple mediastinum and double lung door lymph node metastasis were smaller than before.
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case_images: F1
case_images: An enhanced chest CT suggested interstitial pneumonia and a tumor in the upper lobe of the left lung with multiple lymph node metastasis in the mediastinum and bilateral hilum (Fig. 1a, b, c, g, h, i). A chest CT scan in October 2021 showed new interstitial inflammation in the right lung, with a larger area than before durvalumab treatment (Fig. 1d, e), while the tumor in the left lung and lymph nodes in the mediastinum and bilateral hilum were smaller (Fig. 1f, j, k, l).
case_images: Timeline of the present case.
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case_images: PMC11249548_01_cro-2024-0017-0001-538429_F02.jpg
case_images: F2
case_images: Unfortunately, the patient did not respond to treatment and eventually died 1 month after starting dulvalizumab treatment (Fig. 2).
case_images: Blood pressure and oxygen saturation of the patient. SBP, systolic blood pressure; DBP, diastolic blood pressure.
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case_images: PMC11249548_01_cro-2024-0017-0001-538429_F03.jpg
case_images: F3
case_images: The changes in blood pressure and oxygen saturation during the cytokine storm phase are shown in Figure 3.