case_images: PMC9096240_01
case_images: Ultrasound examination of the mass in the right paralumbar fossa. The mass was demarcated to the liver (not shown in the picture) and contained individual cavities.
case_images: fvets-09-869017-g0001.jpg
case_images: PMC9096240_01_fvets-09-869017-g0001.jpg
case_images: F1
case_images: The mass in the right paralumbar fossa was further examined by ultrasound, it was well-demarcated against the liver, the major part was hyperechogenic with single anechogenic cavities (Figure 1).
case_images: (A,B) Abomasal fibrosarcoma from a goat. (A) Fibrosarcoma in toto with adjacent mesenterium and mesenterial metastasis (arrow). (B) Fibrosarcoma - cross section, showing multiple internal caverns (*) filled with large quantities of seorsanguinous fluids and fibrin accumulations during necropsy.
case_images: fvets-09-869017-g0002.jpg
case_images: PMC9096240_01_fvets-09-869017-g0002.jpg
case_images: F2
case_images: The pylorus of the abomasum showed a multinodular, cavernous proliferation of 45 x 50 x 40 cm in dimension and multiple adhering duodenal loops, extending from the pyloric wall into the adjacent mesentery (Figure 2A). Caverns inside the proliferation were filled with large amounts of serosanguineous fluid and fibrin accumulations (Figure 2B).
case_images: (A-D) Microscopic aspects of an abomasal fibrosarcoma from a goat. (A) Hematoxylin and eosin staining showing an intact mucosal layer (M) and bundles and streams of neoplastic spindle-cells (*) infiltrating into the tunica muscularis (inlet); (B) neoplastic cells showing anisokaryosis and anisocytosis (arrowhead) as well as mitotic figures (arrow); (C) highly positive immunohistochemical detection of vimentin in neoplastic cells, immunoreactivity was especially prominent in the cytoplasm of neoplastic cells (arrowheads); (D) lack of immunohistochemical detection of smooth muscle actin (SMA) in tumor cells, SMA was detected only in the tumor associated vasculature (*); (A) images taken at 10x (overview) and 50x (inlet) magnification, scalebars indicating 500 mum and 200 mum respectively; (B-D) images taken at 200x magnification, scalebar indicating 20 mum.
case_images: fvets-09-869017-g0003.jpg
case_images: PMC9096240_01_fvets-09-869017-g0003.jpg
case_images: F3
case_images: Neoplastic cells were arranged in unorganized bundles and streams supported by moderate amounts of fibrovascular stroma (Figure 3A). Cells were characterized by severe anisokaryosis and anisocytosis, and a mitotic rate of up to two mitoses per high power field was observed (Figure 3B). Neoplastic cells in the abomasal mass stained positively for vimentin (Figure 3C, a marker of mesenchymal cells) and negative for smooth muscle actin (SMA, Figure 3D, a marker of smooth muscle tissue) as well as tyrosinkinase KIT (KIT, a marker for cells of gastrointestinal stromal tumors, data not shown) and cluster of differentiation 31 (CD31, a marker for endothelial cells, data not shown).