case_images: PMC11786293_01
case_images: Images of the present case. (A) Yellowish tumors in the right and left edges of the tongue (arrowheads); (B) Bilateral adipose tissue in the tongue on CT (arrowheads). The right side was 39.0 x 9.5 mm and the left side was 31.2 x 11.9 mm; MRI reveals adipose tissue with a hyperintense signal on T1-weighted imaging and a hypointense signal on T2-weighted imaging (C: T1-weighted, D: T2-weighted, arrowheads); (E) Unencapsulated adipose tissue invading the lingual muscle (arrowhead); (F) Unencapsulated mature adipose tissue is found (arrowhead). No taste buds were found in the epithelium (arrow). Hematoxylin and eosin stain. Scale bar: 500 mum.. CT, Computed tomography; MRI, Magnetic resonance imaging
case_images: cureus-0017-00000076779-i01.jpg
case_images: PMC11786293_01_cureus-0017-00000076779-i01.jpg
case_images: FIG1
case_images: Mild indurations in the bilateral tongue were observed (Figure 1A). Computed tomography revealed adipose tissue in the bilateral tongue (Figure 1B), but no lipomatous tumors in his neck or trunk. Magnetic resonance imaging (MRI) revealed a lesion composed of adipose tissue with a hyperintense signal on T1-weighted imaging and a hypointense signal on T2-weighted imaging (Figures 1C, 1D). As his dysgeusia did not improve after one month of oral zinc acetate dehydrate at a dose of 25 mg twice a day, and to also address his speaking and swallowing difficulties, we performed lateral glossectomy twice under general anesthesia (Figure 1E). Histologic examination revealed mature lipocytes with fibrous septa incorporating skeletal muscle and no taste buds in the epithelium (Figure 1F).
case_images: Flow diagram for the literature search. SLT, Symmetric lipomatosis of the tongue
case_images: cureus-0017-00000076779-i02.jpg
case_images: PMC11786293_01_cureus-0017-00000076779-i02.jpg
case_images: FIG2
case_images: We reviewed 17 articles comprising 18 patients (15 men and three women) who met the inclusion criteria (Figure 2).
case_images: PMC11786293_02