case_images: PMC8088479_01
case_images: (a and b) Sagittal T2-weighted MRI scans taken at the time of presentation show a slightly hyperintense heterogeneous mass at the level of T8-T9. (c and d) T1-weighted MRI scans taken after gadolinium administration show a hypointense mass with circumferential enhancement. Axial T1 (e) and T2 (f) images show an extramedullary intradural dumbbell-shaped mass.
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case_images: PMC8088479_01_SNI-12-164-g001.jpg
case_images: F1
case_images: T8-T9. To further characterize the spinal lesion, MRI imaging was obtained and confirmed the presence of a heterogeneous mass at the left T8 that was hyperintense on T2-weighted and hypointense on T1-weighted images [Figure 1].
case_images: Intraoperative view of the dark, dumbbell-shaped tumor with apparent hemorrhage within the dural sac near the left T8 spinal nerve.
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case_images: F2
case_images: A dark, dumbbell-shaped mass could be seen extending from the left spinal column grossly [Figure 2].
case_images: (a) Tumor is circumscribed with cells in fascicles and nests. (b) Fascicles and nests composed of plump spindle cells. (c) Adipose-like cells admixed with tumor cells. (d) Melanin pigment deposition in the tumor cells (hematoxylin-eosin, original magnifications x40 (a), x100 (b), x200 (c and d)).
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case_images: PMC8088479_01_SNI-12-164-g003.jpg
case_images: F3
case_images: Post-operative histological examination showed fascicles and nests of plump spindle cells, consistent with schwannoma [Figure 3]. Variable amounts of melanin were also seen within tumor cells [Figure 3], leading to further immunohistochemical staining.
case_images: (a) S100 expression in tumor cells. (b) SOX10 expression in tumor cells. (c) HMB-45 expression in tumor cells. (d) MART-1 expression in tumor cells (original magnification x100 (a through d)).
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case_images: PMC8088479_01_SNI-12-164-g004.jpg
case_images: F4
case_images: Tumor sections showed positive expression of S100, SOX10, HMB-45, and MART-1 [Figure 4], compatible with a diagnosis of MS.
case_images: Sagittal (a) and axial (b) T2-weighted MRI images taken 2 months after the removal of a spinal MS tumor.
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case_images: F5
case_images: Imaging did not show any local recurrence of the tumor [Figure 5].