case_images: PMC7267678_01
case_images: Frontal view after explantation of the breast implants in our 62-year-old patient.
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case_images: About three months later our patient noted an erythematous area on the lateral side of the inframammary fold of the right breast (Fig. 1, Fig. 2).
case_images: Silicone residuals after explantation of the breast implants on protocol breast MRI. The diameter of the largest silicone pocket (left) is 2.3 x 1.5 cm.
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case_images: This showed bilateral subpectoral residual silicone particles, with the largest silicone pocket of about 2,3 x 1,5 cm in the left breast (Fig. 3, Fig. 4).
case_images: a) Immunohistochemistry (ALK-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. b) Immunohistochemistry (CD3-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. c) Immunohistochemistry (CD5-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. d) Immunohistochemistry (CD20-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient. e) Immunohistochemistry (CD23-staining) of tissue from the lateral and medial lower quadrant of the left breast of our 62-year-old patient.
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case_images: PMC7267678_01_gr5.jpg
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case_images: B-lymphocytic infiltration (CD20+, CD5+, CD23+, ALK-) in both capsules, highly suggestive for CLL/SLL (Fig. 5a-e). Breast implant associated anaplastic large cell lymphoma (BIA-ALCL) was considered but excluded as CD30 tested negative.