case_images: PMC6503795_01
case_images: Extraoral examination revealing facial asymmetry on the right side of the face
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case_images: F1
case_images: On inspection, a solitary, diffuse swelling over the middle-third region of the face was noticed [Figure 1].
case_images: Intraoral examination revealing a well-defined solitary erythematous growth in the right retromolar region
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case_images: F2
case_images: Intraoral examination [Figure 2] revealed a well-defined solitary erythematous growth in the right retromolar region at the previous extraction site.
case_images: Orthopantamograph revealing ill-defined radiolucency encompassing the entire right side of the mandible
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case_images: F3
case_images: Orthopantamograph [Figure 3] revealed ill-defined radiolucency encompassing entire right side of the mandible extending posteriorly from 47 to ramus, angle, coronoid and condylar process.
case_images: Reconstructed computed tomography scan revealing large expansile lytic on the right posterior mandible region (a) Completely resorbed Medial aspect of the ramus with alveolar erosion(b)
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case_images: F4
case_images: Reconstructed computed tomography scan revealed large expansile lytic lesion with irregular borders on the right posterior mandible region [Figure 4a]. Medial aspect of the ramus was completely resorbed [Figure 4b].
case_images: Photomicrograph showing solid sheets of plasma cells (a) and also anaplastic cells with occasional binucleated forms (b)
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case_images: PMC6503795_01_JOMFP-23-136-g005.jpg
case_images: F5
case_images: Histopathology revealed solid sheets of densely packed, uniformly appearing round-to-ovoid cells with eccentrically placed nucleus resembling plasma cells [Figure 5a]. Anaplastic cells with hyperchromatic nucleus and occasional binucleated forms [Figure 5b] suggesting malignancy were also observed.
case_images: Immunohistochemistry showing strong positivity for CD138 (a), MUM1 (b), variable cell membrane positivity for CD45 (c) and negativity for CD20 (d)
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case_images: PMC6503795_01_JOMFP-23-136-g006.jpg
case_images: F6
case_images: Based on laboratory findings, the final diagnosis of solitary plasmacytoma of the mandible was given which was then confirmed by immunohistochemistry which revealed strong positivity for CD138 [Figure 6a], MUM1 [Figure 6b], variable cell membrane positivity for CD45 [Figure 6c] and negativity for CD20 [Figure 6d].