case_images: PMC9098364_01
case_images: Papillomavirus lesions in the kid showing a mass on the lower lip, buccal mucosa, hard and soft palates, cauliflower-like appearance.
case_images: CRIVEM2022-1598256.001.jpg
case_images: PMC9098364_01_CRIVEM2022-1598256.001.jpg
case_images: fig1
case_images: The histopathology result in this case of caprine papilloma tissues. (a) Overall hyperproliferation on the epidermis layer, characterized by thickening of the epidermal layer (black, double head arrow) and formation of rete peg which from epidermis layer extended to dermis layer (white arrow), indicating acanthosis. (b) Presence of nucleated cells within the stratum corneum (red arrow), indicating parakeratotic hyperkeratosis. Evidence of angiogenesis with the presence of the luminal structure surrounded by the endothelial cell (yellow arrow) and filled with some red blood cells. Hypercellularity of the dermis layer, filled with spindle-shaped fibroblast (blue arrow). (c) Presence of ballooning cell indicating koilocytosis (green arrow). H&E staining and magnification (a) 4x, (b) 10x, and (c) 40x.
case_images: CRIVEM2022-1598256.002.jpg
case_images: PMC9098364_01_CRIVEM2022-1598256.002.jpg
case_images: fig2
case_images: Similarly, nucleated cells within the stratum corneum (red arrow) were observed indicating parakeratotic hyperkeratosis (Figure 2(b)). Moreover, evidence of angiogenesis was detected with the presence of the luminal structure surrounded by the endothelial cell (yellow arrow), filled with some red blood cells (hypercellularity of the dermis layer), with spindle-shaped fibroblast (blue arrow), were also observed (Figure 2(b)). On a high magnification (40x), there was also marked ballooning and koilocytosis which is a diagnostic marker for papillomavirus infection and can be observed morphologically in histological sections (Figure 2(c)).
case_images: The progression of treatment after administration of flunixin meglumine, Penstrep (procaine penicillin, dihydrostreptomycin sulphate), and Vitavet (multivitamin-vitamins A, D3, and B12). There was marked regression of the oral mass fibrosis growth from (a) commencement of treatment to (g) final discharge.
case_images: CRIVEM2022-1598256.003.jpg
case_images: PMC9098364_01_CRIVEM2022-1598256.003.jpg
case_images: fig3