case_images: PMC3922991_01
case_images: CT scan large mass in the right lobe of thyroid grand invasive to the upper mediastinum.
case_images: 40064_2013_810_Fig1_HTML.jpg
case_images: PMC3922991_01_40064_2013_810_Fig1_HTML.jpg
case_images: Fig1
case_images: CT scans revealed a sizable lesion with imaging features of a submerged goiter, invasive to the upper mediastinum (diameter = 66 mm) with no enlarged mediastinal or axillary lymph nodes (Figures  1: large mass in the right lobe of thyroid grand invasive to the upper mediastinum).
case_images: H-E staining showing both thyroid follicles in the down left part and tumor cells in the upper right part, original magnification x100.
case_images: 40064_2013_810_Fig2_HTML.jpg
case_images: PMC3922991_01_40064_2013_810_Fig2_HTML.jpg
case_images: Fig2
case_images: The tumor consisted of uniform, small to medium sized cells with a round nucleus, finely dispersed chromatin, inconspicuous nucleoli and scant cytoplasm (Figure  2: hematoxylin-eosin-staining H-E showing both thyroid follicles in the down left part and tumor cells in the upper right part, original magnification x100).
case_images: Immunoperoxidase staining for CK20 showing positive tumor cells, original magnification x400.
case_images: 40064_2013_810_Fig3_HTML.jpg
case_images: PMC3922991_01_40064_2013_810_Fig3_HTML.jpg
case_images: Fig3
case_images: The tumor was characterized of positive immunohistochemical reaction for antibodies to cytokeratin CAM 5.2, cytokeratin 20 CK20 (Figure  3: immunoperoxidase staining for CK20 showing positive tumor cells, original magnification x400), neurofilaments NF (Figure  4: immunoperoxidase staining for NF showing positive tumor cells, original magnification x400) and neuroendocrine markers chromogranin, synaptophysin and CD56.
case_images: Immunoperoxidase staining for NF showing positive tumor cells, original magnification x400.
case_images: 40064_2013_810_Fig4_HTML.jpg
case_images: PMC3922991_01_40064_2013_810_Fig4_HTML.jpg
case_images: Fig4
case_images: The tumor was characterized of positive immunohistochemical reaction for antibodies to cytokeratin CAM 5.2, cytokeratin 20 CK20 (Figure  3: immunoperoxidase staining for CK20 showing positive tumor cells, original magnification x400), neurofilaments NF (Figure  4: immunoperoxidase staining for NF showing positive tumor cells, original magnification x400) and neuroendocrine markers chromogranin, synaptophysin and CD56.