case_images: PMC11253126_01
case_images: CT presented thickened interlobular septa in both lungs (A) and a 1.1cm hypodense nodule in the right upper posterior lobe of the liver (B). Conventional ultrasound revealed a 1.4 x 1.1cm hypoechoic nodule in the upper segment of the right posterior lobe of the liver (C, D).
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case_images: B factor: complement C3 0.7690g/L, complement C4 0.1360g/L, VTE score: 1; Sputum and pharyngeal bacteria culture did not show obvious abnormalities. Chest CT showed multiple nodules in both lungs, mainly in the upper lobes of both lungs, which were suspected to be inflammatory nodules. Both lungs had mild inflammation with thickened interlobular septa, which were alleged to be mild pulmonary oedema ( Figure 1A ). A slightly hypodense nodule with a long diameter of 1.1cm was found in the right upper posterior lobe of the liver, which was mildly enhanced and suspected of inflammation ( Figure 1B ). Routine ultrasound examination showed a 1.4x1.1cm hypoechoic nodule under the upper capsule of the right posterior lobe of the liver, with clear boundaries, regular shape and no blood flow signal ( Figure 1C, D ).
case_images: CEUS showed that the uniformly hyper-enhanced solid component of the nodule in the arterial phase (A), the eluted enhancement in the late arterial (B) and the slight low enhancement in the portal and parenchymal phases (C, D).
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case_images: In the arterial phase, the solid component of the nodule rapidly becomes uniformly hyper-enhanced, and the scope becomes larger after enhancement ( Figure 2A ). Then, the enhancement washout begins in the late arterial phase ( Figure 2B ). The portal and parenchymal phases showed slightly less enhancement ( Figure 2C, D ).
case_images: Microscopy showed the HE staining (A) (X200) and the immunohistochemical staining of the CD20(+), CD79a(+), CD10(+), Bcl6(+), MUM1(+), Bcl2(+), c-myc(+) and Ki67(+) expression (B-I) (X200).
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case_images: PMC11253126_01_fonc-14-1380392-g003.jpg
case_images: f3
case_images: An immunohistochemical study showed that the tumor cells were positive for CD20, CD79a, CD10, Bcl-6, Bcl-2, c-Myc and MUM1 ( Figure 3 ).