case_images: PMC2782172_01
case_images: A nodular submucosal tumor is noted on the left side of hard palate.
case_images: jkms-20-687-g001.jpg
case_images: PMC2782172_01_jkms-20-687-g001.jpg
case_images: F1
case_images: A 34-yr-old male patient was admitted our hospital with a painless swelling of the left hard palate (Fig. 1).
case_images: The paranasal CT scan showing a contrast-enhancing mass lesion in left side hard palate with focal bony destruction (*).
case_images: jkms-20-687-g002.jpg
case_images: PMC2782172_01_jkms-20-687-g002.jpg
case_images: F2
case_images: A paranasal sinus CT-scan revealed a contrast-enhancing mass lesion in left side hard palate with focal bony destruction (Fig. 2).
case_images: Light microscopy of the tumor shows closely packed small round cells with abundant thin-walled vessels (H&E, x40).
case_images: jkms-20-687-g003.jpg
case_images: PMC2782172_01_jkms-20-687-g003.jpg
case_images: F3
case_images: Histological examination of hematoxylin-eosin stained sections showed a homogeneous population of closely packed small neoplastic cells with abundant fibrovascular stroma (Fig. 3).
case_images: Acini of minor salivary gland are seen at the periphery of tumor (arrow) (H&E, x10).
case_images: jkms-20-687-g004.jpg
case_images: PMC2782172_01_jkms-20-687-g004.jpg
case_images: F4
case_images: Remnant salivary gland tissue was observed at the tumor's periphery (Fig. 4).
case_images: Most of the tumor cells have scanty cytoplasm and round or oval nuclei with fine powdery chromatin (H&E, x400).
case_images: jkms-20-687-g005.jpg
case_images: PMC2782172_01_jkms-20-687-g005.jpg
case_images: F5
case_images: Most of the individual cells had scanty cytoplasm, indistinct borders and round or oval nuclei with fine powdery chromatin (Fig. 5).
case_images: Strong membranous MIC2/CD99 immunoreactivity (LSAB, x200).
case_images: jkms-20-687-g006.jpg
case_images: PMC2782172_01_jkms-20-687-g006.jpg
case_images: F6
case_images: The CD99/MIC2 stain exhibited strong membranous staining (Fig. 6).
case_images: EWS/FLI1 chimeric gene of approximately 260 bp is identified by RT-PCR in this case (arrow) (M, size marker; lane 1, positive control; lane 2, negative control; lane 3, this case).
case_images: jkms-20-687-g007.jpg
case_images: PMC2782172_01_jkms-20-687-g007.jpg
case_images: F7
case_images: The RT-PCR showed the presence of the EWS-FLI-1 fusion transcript, which is of the t(11;22) translocation characteristic of ES and primitive neuroectodermal tumor (Fig. 7).