case_images: PMC10762310_01
case_images: The in-phase T1-weighted imaging (T1WI) of abdominal magnetic resonance imaging (MRI) reveals a high and low mixed signal nodule about 2.0 cm x 1.8 cm in size in the medial segment of the left lobe of liver (A, arrow); The reverse phase of T1WI shows that the signal of the high signal part of the original nodules has become low (B, arrow), indicating fat composition; The nodule shows slightly high signal on T2-weighted imaging (T2WI) (C) and diffusion weighted imaging (D). On contrast-enhanced T1WI, the lesion shows significant enhancement in the arterial phase (E) and rapid resolution in the venous phase (F), presenting a typical "fast in and fast out" enhancement pattern.
case_images: fmed-10-1322048-g001.jpg
case_images: PMC10762310_01_fmed-10-1322048-g001.jpg
case_images: fig1
case_images: On magnetic resonance imaging (MRI as shown in Figure 1), the lesion presented uneven short T1 and long T2 signals, with a clear "fast in and fast out" appearance on contrast-enhanced scans.
case_images: (A) The maximum intensity projection of the positron emission tomography (PET)/computed tomography (CT) shows a nodule (arrow) on the left side of the spine with increased uptake of fluorine-18 fluorodeoxyglucose (18F-FDG), with a maximum standardized uptake value (SUVmax) of 5.4. Axial images CT (B) showed the corresponding nodule at the medial segment of the left lobe of liver, with solid components of equal hepatic parenchymal density and low-density adipose tissue (arrow). Axial PET (C) and PET/CT fusion image (D) showed an increased 18F-FDG uptake of the solid component of the nodule (arrows).
case_images: fmed-10-1322048-g002.jpg
case_images: PMC10762310_01_fmed-10-1322048-g002.jpg
case_images: fig2
case_images: To determine the best course of treatment, the patient underwent a positron emission tomography (PET)/CT examination (PET/CT imaging presented in Figure 2), which revealed increased fluorine-18 fluorodeoxyglucose (18F-FDG) uptake in the lesion, while no significant abnormal radioactive uptake was observed throughout the rest of the body.
case_images: (A) Hematoxylin-Eosin staining shows that tumor cells are composed of epithelioid cells, with smooth muscle (white arrow) and adipose tissue (red arrow) visible within the tumor tissue. Immunohistochemistry shows that tumor cells positively express HMB45 (B), melan-A (C), smooth muscle actin (SMA) (D).
case_images: fmed-10-1322048-g003.jpg
case_images: PMC10762310_01_fmed-10-1322048-g003.jpg
case_images: fig3
case_images: The tumor cells as shown in Figure 3 were composed of epithelioid cells rich in transparent cytoplasm and eosinophilic granules.