case_images: PMC11748404_01
case_images: (A & B) endoscopic findings before H. Pylori eradication: Diffuse redness, mucosal swelling, and enlarged folds are observed in the gastric corpus. (C&D) endoscopic findings after eradication: Remnants of the oxyntic mucosa sticky adherent dense mucus and scattered minute whitish protrusions were identified at the greater curvature site of the gastric corpus.
case_images: omae178f1.jpg
case_images: PMC11748404_01_omae178f1.jpg
case_images: f1
case_images: In November 2021, esophagogastroduodenoscopy (EGD) was performed, which revealed diffuse redness, mucosal swelling, enlarged folds in the gastric corpus (Fig. 1A and B), and chronic atrophic gastritis (open type: O-1). dense mucus and scattered minute whitish protrusions at the greater curvature site of the gastric corpus (Fig. 1 C and D).
case_images: (A) Biopsy specimens from the greater curvature of the gastric corpus before H. Pylori eradication; moderately infiltrating inflammatory neutrophilic cells in the gastric superficial mucosa are shown. (bar = 200 mum). (B) Biopsy specimens from the greater curvature of the gastric corpus after H. Pylori eradication; infiltrating lymphocytes increased near the muscularis mucosa. (bar = 200 mum). The arrow shows infiltrating lymphocyte sites. (C & D) biopsy specimens from the greater curvature of the gastric corpus before (C) and after (D) H. Pylori eradication. Chromogranin A-positive cells increased in the superficial mucosa after (D) H. Pylori eradication. (E) Biopsy specimens from the greater curvature of the gastric corpus after H. Pylori eradication; infiltrating inflammatory neutrophilic cells decreased in the superficial mucosa but infiltrating lymphocytes increased in the sub-superficial mucosa.
case_images: omae178f2.jpg
case_images: PMC11748404_01_omae178f2.jpg
case_images: f2
case_images: Biopsy specimens from the greater curvature of the gastric corpus revealed moderately infiltrating inflammatory neutrophilic cells in the superficial gastric mucosa (Fig. 2A). Chromogranin A-positive cells increased (Fig. 2C and D) in the superficial mucosa (Fig. 2C and D), and infiltrating lymphocytes increased in the superficial mucosa (Fig. 2E). Consistent with this, it was reported that the early phase of AIG is characterized by diffuse basal-predominant inflammation within the mucosa.