case_images: PMC3535818_01
case_images: Photograph of patient showing slightly raised lesion on the forehead near the medial side of the left eyebrow.
case_images: CRIM.DM2012-796818.001.jpg
case_images: PMC3535818_01_CRIM.DM2012-796818.001.jpg
case_images: fig1
case_images: We present a case of a five-year-old boy who presented with a slightly raised, painless lesion on base of the nose near the medial side of a the left eyebrow (Figure 1) since 6 months.
case_images: Cytosmear showing loosely cohesive clusters comprising oval to spindle cells in hemorrhagic background (10x, MGG) and inset showing tumor cells having oval hyperchromatic nuclei, inconspicuous nucleoli, and poorly defined cytoplasmic borders (40x, MGG).
case_images: CRIM.DM2012-796818.002.jpg
case_images: PMC3535818_01_CRIM.DM2012-796818.002.jpg
case_images: fig2
case_images: Pathological Finding: May-Grunwald Giemsa (MGG) stained cytological smears showed scanty cellularity comprising few cohesive clusters and singly dispersed oval to spindle cells in hemorrhagic background (Figures 2 and 3). Tumor cells had oval hyperchromatic nuclei, inconspicuous nucleoli, and poorly defined cytoplasmic borders (Figure 2 inset).
case_images: Cytosmear showing loosely cohesive clusters comprising cells with oval to spindle nuclei ((a) and (b)) (40x, MGG).
case_images: CRIM.DM2012-796818.003.jpg
case_images: PMC3535818_01_CRIM.DM2012-796818.003.jpg
case_images: fig3
case_images: Pathological Finding: May-Grunwald Giemsa (MGG) stained cytological smears showed scanty cellularity comprising few cohesive clusters and singly dispersed oval to spindle cells in hemorrhagic background (Figures 2 and 3).
case_images: Section showing spindle cells arranged in short fascicles and storiform pattern (10x, H&E) and inset showing tumor cells with oval nuclei, vesicular chromatin, inconspicuous nucleoli, and scanty to moderate cytoplasm (40x, H&E).
case_images: CRIM.DM2012-796818.004.jpg
case_images: PMC3535818_01_CRIM.DM2012-796818.004.jpg
case_images: fig4
case_images: Hematoxylin and eosin stained sections showed cellular and poorly circumscribed tumor in the dermis comprising interwoven bundles and fascicles of uniform spindle shaped cells arranged in "storiform" or "cartwheel" pattern (Figure 4). The tumor cells had monotonous appearance with oval nuclei, vesicular chromatin, inconspicuous nucleoli, and scanty to moderate cytoplasm (Figure 4 inset).
case_images: Section showing tumor cells focally positive for CD34 (10x, CD34 DAB).
case_images: CRIM.DM2012-796818.005.jpg
case_images: PMC3535818_01_CRIM.DM2012-796818.005.jpg
case_images: fig5
case_images: Tumor cells were positive for both vimentin and CD-34 (Figure 5).