case_images: PMC11250684_01
case_images: a Contrast-enhanced T1 imaging of the anterior orbit showing enlarged contrast enhancing m obliquus inferior dx (arrowhead) and lacrimal gland bilateral (arrows). b Contrast-enhanced T1 imaging of the dorsal orbit with enlarged right lacrimal gland (arrow) and rectus muscles predominantly on the right side (arrowheads).
case_images: cop-2024-0015-0001-539184_F01.jpg
case_images: PMC11250684_01_cop-2024-0015-0001-539184_F01.jpg
case_images: F1
case_images: It also revealed enlargement of the anterior portion of the inferior rectus muscle and a slightly enlarged lacrimal gland in the right orbit (shown in Fig. 1).
case_images: a 18F-FDG PET-CT of the face with pathological uptake in orbital muscles bilaterally (arrowheads) and left lacrimal gland (arrow). b 18F-FDG PET-CT of the thorax with pathological uptake surrounding ruptured silicone breast implant (arrowhead) and in lymph nodes in the right pulmonary hilus (arrow).
case_images: cop-2024-0015-0001-539184_F02.jpg
case_images: PMC11250684_01_cop-2024-0015-0001-539184_F02.jpg
case_images: F2
case_images: In addition, pathological metabolism was detected in one retromandibular lymph node on the left side, in multiple lymph nodes in the right axillae, along the right common and internal carotid artery, in the thoracic wall right of the sternum, in the hilum of the right lung and left side of the pelvis, as well as in the internal oblique muscle of the abdominal wall (shown in Fig. 2).
case_images: Histological and immunohistochemical characterization of the lacrimal gland. a Low magnification reveals the lobular structure of the lacrimal gland interspersed with areas of granulomatous inflammation (arrowheads), stained with hematoxylin and eosin. b Higher magnification of these granulomatous regions shows the presence of multinucleated foreign body giant cells. c Immunohistochemical analysis (CD68) highlights an elevated concentration of macrophages within the granulomas. d Examination under polarized light reveals birefringent material within the granulomas (arrows).
case_images: cop-2024-0015-0001-539184_F03.jpg
case_images: PMC11250684_01_cop-2024-0015-0001-539184_F03.jpg
case_images: F3
case_images: The material was birefringent on polarized light (shown in Fig. 3).