case_images: PMC11402096_01
case_images: Gross appearance of superficial angiomyxoma: (a) White polypoid mass with superficial papillary elevations (cauliflower-like). (b) The cut surface showing white translucent, glistening appearance.
case_images: 10.1177_2050313X241281263-fig1.jpg
case_images: PMC11402096_01_10.1177_2050313X241281263-fig1.jpg
case_images: fig1-2050313X241281263
case_images: At gross examination, the tissue specimen was described as a white polypoid lesion, upraised on the narrowed stalk, with the maximal diameter of 3 cm (Figure 1(a)). The cut surface was white, translucent, glistening, and gelatinous (Figure 1(b)).
case_images: Histopathological images: (a) HE image, showing spindle and stellate cells dispersed in myxoid stroma, thin-walled blood vessels and inflammatory cells, concentrated mostly in subepithelial site (original magnification 40x). (b) Alcian blue staining showing hypocellular myxoid stroma (original magnification 40x). (c) Positive expression of Vimentin in tumor cells (original magnification 40x). (d) High expression of CD34 in blood vessels and moderate positive expression in tumor cells (original magnification 40x). (e) Expression of Ki-67 showing a very low proliferation index in tumor cells, and positive reactive expression in epithelia (original magnification 40x). (f) Tumor cells showing negative expression for S100 (original magnification 100x).
case_images: 10.1177_2050313X241281263-fig2.jpg
case_images: PMC11402096_01_10.1177_2050313X241281263-fig2.jpg
case_images: fig2-2050313X241281263
case_images: Scattered tumor cells showed scant cytoplasm and fine delicate cytoplasmic extensions (Figure 2(a)). The presence of loose hypocellular myxoid stroma was highlighted with alcian blue stain (Figure 2(b)). Diffuse cytoplasmic staining for Vimentin was detected in scattered tumor spindle and stellate cells (Figure 2(c)). Immunostaining with CD34 was more prominent in endothelial cells of blood vessels, and it showed moderate cytoplasmic expression in tumor cells (Figure 2(d)), whereas described cells were negative for S100 (Figure 2(f)). The proliferation index detected by immunostaining with Ki67 was below 4% (Figure 2(e)).