case_images: PMC6129685_01
case_images: CT scan of chest showing a mediastinal mass.
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case_images: PMC6129685_01_gr1.jpg
case_images: fig0005
case_images: The rest of past medical history was unremarkable and she did not show any signs/symptoms of hypo or hyperthyroidism (Fig. 1, Fig. 2, Fig. 3, Fig. 4) . A CT scan of chest, abdomen and pelvis showed a 15*15 cm localized anterior mediastinal mass invading through the sternal bone in the center and protruding outward from the skin (Fig. 1).
case_images: Gross morphology showing a highly vascular soft mass.
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case_images: PMC6129685_01_gr2.jpg
case_images: fig0010
case_images: The specimen was sent for biopsy (See Fig. 2).
case_images: Post radiotherapy bone scan showing good iodine uptake.
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case_images: PMC6129685_01_gr3.jpg
case_images: fig0015
case_images: The rest of past medical history was unremarkable and she did not show any signs/symptoms of hypo or hyperthyroidism (Fig. 1, Fig. 2, Fig. 3, Fig. 4) . With a post therapy scan showing good uptake of therapeutic dose by post-operative residual functioning thyroid tissue over thyroid bed (See Fig. 3).
case_images: [A] Tumor infiltration into bone (arrows). (HnE stain;100x magnification) [B] Tumor infiltration into cartilage (arrows). (HnE stain;40x magnification) [C] Tumor infiltration into muscle fibers (arrows). (HnE stain; 400x magnification) [D] Tumor cells showing follicular arrangement and nuclei exhibiting enlargement, overlapping and clearing. (HnE stain;400x magnification).
case_images: gr4.jpg
case_images: PMC6129685_01_gr4.jpg
case_images: fig0020
case_images: The biopsy of the thyroid specimen showed benign thyroid tissue, however, the mediastinal mass showed follicular variant of papillary thyroid cancer (See Fig. 4).