case_images: PMC5253496_01
case_images: PMC5253496_02
case_images: PMC5253496_03
case_images: (a) Pedigree tree of the patient. (b) GCK gene analysis of the patient (grandmother). The heterozygosity of exon 6 c.590T>C (p.M197T), a novel GCK-activating mutation, was identified.
case_images: CRIE2017-4709262.001.jpg
case_images: PMC5253496_03_CRIE2017-4709262.001.jpg
case_images: fig1
case_images: The sequencing of exon 6 in her DNA revealed the same mutation as her son and grandchild, and she was diagnosed with congenital hyperinsulinemic hypoglycemia (Figure 1).