case_images: PMC8213507_01
case_images: Computed tomography revealing bone metastasis (arrow). (a) C5, (b) L4, (c) S1, and (d) left acetabular cartilage.
case_images: CRIE2021-3024639.001.jpg
case_images: PMC8213507_01_CRIE2021-3024639.001.jpg
case_images: fig1
case_images: Computed tomography (CT) revealed a thyroid tumor and multiple vertebral bone metastases (C5, L4, S1, and left acetabular cartilage) (Figure 1).
case_images: Pathological diagnosis of poorly differentiated carcinoma derived from follicular thyroid carcinoma with minimal invasion; Victoria Blue hematoxylin and eosin staining, 200x.
case_images: CRIE2021-3024639.002.jpg
case_images: PMC8213507_01_CRIE2021-3024639.002.jpg
case_images: fig2
case_images: Pathological diagnosis was poorly differentiated carcinoma derived from follicular thyroid carcinoma with minimal invasion (Figure 2).
case_images: Iodine-131 scintigraphy after radioactive iodine therapy. No uptake was observed in the metastatic lesions.
case_images: CRIE2021-3024639.003.jpg
case_images: PMC8213507_01_CRIE2021-3024639.003.jpg
case_images: fig3
case_images: However, no uptake was observed in the metastatic lesions (Figure 3).
case_images: Magnetic resonance imaging revealing thickening of the right inferior rectus muscle (asterisk).
case_images: CRIE2021-3024639.004.jpg
case_images: PMC8213507_01_CRIE2021-3024639.004.jpg
case_images: fig4
case_images: One year after RAI, the patient presented with diplopia, and magnetic resonance imaging revealed a thickening of the right inferior rectus muscle (Figure 4).
case_images: Change of thyroglobulin (Tg) and thyroglobulin antibody (TgAb) levels (from thyroid-associated ophthalmopathy occurrence to improvement).
case_images: CRIE2021-3024639.005.jpg
case_images: PMC8213507_01_CRIE2021-3024639.005.jpg
case_images: fig5
case_images: However, Tg and TgAb gradually decreased with sorafenib and lenvatinib administration, and TAO was improved two years after occurrence (Figure 5).