case_images: PMC10644375_01
case_images: (A) Timeline of key events. GTR, Gross total resection; NTCT, network-targeting combination therapy (see text for details); CR, Complete remission. (B) Lumbar spine MRI T1 sagittal LEFT: at relapse and RIGHT: 10 months after NTCT during remission.
case_images: fonc-13-1210224-g001.jpg
case_images: PMC10644375_01_fonc-13-1210224-g001.jpg
case_images: f1
case_images: Figure 1 ). Following gross total resection (GTR) and conventional chemoradiotherapy 60 Gy in 30 fractions with concurrent temozolomide (TMZ) (75mg/m2/day) followed by adjuvant (TMZ) (150   200 mg/m2 x 5 days every 28 days) x 6 cycles, she achieved a disease-free survival of 24 months from diagnosis before developing back pain that led to the diagnosis of relapse with L3 spinal cord involvement ( Figure 1B ).