case_images: PMC4475516_01
case_images: Bilateral intense arytenoid edema with fullness of the right pyriform sinus.
case_images: CRIOT2015-934926.001.jpg
case_images: PMC4475516_01_CRIOT2015-934926.001.jpg
case_images: fig1
case_images: The remaining laryngeal structures had an intense edematous appearance (Figure 1).
case_images: (a) CT scan with contrast enhancement showing a tumoral mass of the right pyriform sinus extending through the extralaryngeal region with thyroid cartilage destruction and prevertebral area involvement. (b) CT scan demonstrating multiple metastases in both lungs.
case_images: CRIOT2015-934926.002.jpg
case_images: PMC4475516_01_CRIOT2015-934926.002.jpg
case_images: fig2
case_images: Contrast-enhanced CT (Figure 2(a)) and MRI examinations demonstrated a tumoral mass at the right pyriform sinus extending through the extralaryngeal region with thyroid cartilage destruction and prevertebral area involvement. Multiple metastatic nodules were detected in both lungs with thorax CT (Figure 2(b)).
case_images: (a) Hematoxylin and eosin staining showing small cells, round to fusiform in shape with scanty cytoplasm, fine granular nuclear chromatin, and absence of nucleoli. Note the necrosis and crush artifact (original magnification x200). The tumor cells were immunoreactive for (b) pancytokeratin and (c) CD56 (original magnification x200).
case_images: CRIOT2015-934926.003.jpg
case_images: PMC4475516_01_CRIOT2015-934926.003.jpg
case_images: fig3
case_images: The tumor cells were of small size with hyperchromatic, round to oval nuclei and scanty, poorly defined cytoplasm (Figure 3(a)). The tumor cells were immunoreactive for pancytokeratin (Figure 3(b)), CD56 (Figure 3(c)), focal synaptophysin, and thyroid transcription factor- (TTF-) 1 but negative for CD20, leukocyte common antigen, and S100.