case_images: PMC5863397_01
case_images: Clinical picture of the lesion
case_images: CCD-9-132-g001.jpg
case_images: PMC5863397_01_CCD-9-132-g001.jpg
case_images: F1
case_images: A 52-year-old female patient reported with a chief complaint of an enlarging but painless, gingival growth in relation to the lower front tooth region [Figure 1].
case_images: Surgically excised lesion
case_images: CCD-9-132-g002.jpg
case_images: PMC5863397_01_CCD-9-132-g002.jpg
case_images: F2
case_images: The lesion [Figure 2] was surgically excised with electrosurgical unit to minimize bleeding and postoperative discomfort [Figure 3] and subjected to histopathological examination.
case_images: Surgical site after removal of granuloma
case_images: CCD-9-132-g003.jpg
case_images: PMC5863397_01_CCD-9-132-g003.jpg
case_images: F3
case_images: The lesion [Figure 2] was surgically excised with electrosurgical unit to minimize bleeding and postoperative discomfort [Figure 3] and subjected to histopathological examination.
case_images: Vestibuloplasty of shallow sulcus
case_images: CCD-9-132-g004.jpg
case_images: PMC5863397_01_CCD-9-132-g004.jpg
case_images: F4
case_images: Vestibuloplasty was also performed to correct inadequate vestibular depth [Figure 4].
case_images: Histopathological picture showing numerous plasma cells in cytoma
case_images: CCD-9-132-g005.jpg
case_images: PMC5863397_01_CCD-9-132-g005.jpg
case_images: F5
case_images: Histopathological examination revealed a dense fibrovascular connective tissue with sheets of mixed inflammatory cell infiltrates comprising predominantly of plasma cells and few lymphocytes with an overlying parakeratinized stratified squamous epithelium with anastomosing rete pegs [Figures 5 and 6].
case_images: Magnified view of connective tissue stroma
case_images: CCD-9-132-g006.jpg
case_images: PMC5863397_01_CCD-9-132-g006.jpg
case_images: F6
case_images: Histopathological examination revealed a dense fibrovascular connective tissue with sheets of mixed inflammatory cell infiltrates comprising predominantly of plasma cells and few lymphocytes with an overlying parakeratinized stratified squamous epithelium with anastomosing rete pegs [Figures 5 and 6].
case_images: Immunohistochemical examination with kappa chain immunoglobulin markers
case_images: CCD-9-132-g007.jpg
case_images: PMC5863397_01_CCD-9-132-g007.jpg
case_images: F7
case_images: Immunohistochemical examination revealed kappa and lambda light chain immunoglobulin markers [Figures 7 and 8] which are used to differentiate reactive from benign and malignant lesions as was confirmed in our case, with a positive reaction revealing the lesion to be reactive rather than being benign or, malignant in nature.
case_images: Immunohistochemical examination revealing lambda chain immunoglobulin markers
case_images: CCD-9-132-g008.jpg
case_images: PMC5863397_01_CCD-9-132-g008.jpg
case_images: F8
case_images: Immunohistochemical examination revealed kappa and lambda light chain immunoglobulin markers [Figures 7 and 8] which are used to differentiate reactive from benign and malignant lesions as was confirmed in our case, with a positive reaction revealing the lesion to be reactive rather than being benign or, malignant in nature.
case_images: Follow-up examination revealing no reoccurrence of lesion
case_images: CCD-9-132-g009.jpg
case_images: PMC5863397_01_CCD-9-132-g009.jpg
case_images: F9
case_images: The patient was re-called after every 3 months [Figure 9] for 1 year for a follow-up.