case_images: PMC5088313_01
case_images: (a)-(d) Wright Giemsa stained bone marrow aspirate smear with increased number of histiocytes depicting hemophagocytosis (engulfed white and red blood cell precursors).
case_images: CRIID2016-1358742.001.jpg
case_images: PMC5088313_01_CRIID2016-1358742.001.jpg
case_images: fig1
case_images: Aspirate smears showed numerous macrophages with evidence of hemophagocytosis (Figures 1(a)-1(d)).
case_images: (a) Bone marrow biopsy with increased number of histiocytes, focally present in loose aggregates, hematoxylin and eosin stain, 40x. (b) CD163 staining on bone marrow biopsy highlighting histiocytes. (c)-(d) GMS (Gomori-Methenamine Silver) staining on bone marrow biopsy. Numerous budding fungal organisms with morphology consistent with Histoplasma are present.
case_images: CRIID2016-1358742.002.jpg
case_images: PMC5088313_01_CRIID2016-1358742.002.jpg
case_images: fig2
case_images: Well defined granulomas or areas of necrosis were not seen (Figures 2(a) and 2(b)).