case_images: PMC3350070_01
case_images: PMC3350070_02
case_images: PMC3350070_03
case_images: Sagittal T1 (a) and transverse FLAIR (b) MRI of sixth pregnancy (third case) in family 1. Note thin corpus callosum in (a). Irregular ventricular borders, white matter hypoplasia, ventriculomegaly, and periventricular hyperintense signal are demonstrated in (b).
case_images: CRIM.PEDIATRICS2011-307857.001.jpg
case_images: PMC3350070_03_CRIM.PEDIATRICS2011-307857.001.jpg
case_images: fig1
case_images: MRI showed significant loss of white matter in both right and left cerebral hemispheres, with dilatation and irregularity of the lateral ventricular borders, and a thin corpus callosum (Figure 1).
case_images: PMC3350070_04
case_images: Transverse FLAIR MRI from the first case, family 2. Note irregular ventricular border in (a) and in a more rostral section, white matter hyperintense signal more prominent on the left in (b).
case_images: CRIM.PEDIATRICS2011-307857.002.jpg
case_images: PMC3350070_04_CRIM.PEDIATRICS2011-307857.002.jpg
case_images: fig2
case_images: T2-weighted MRI images (Figure 2). The spastic hypertonia of the right upper and lower extremities has been stable in keeping with the diagnosis of right hemiparetic cerebral palsy.
case_images: PMC3350070_05