case_images: PMC6875186_01
case_images: Clinical aspect of intraoral lesions in the palate and alveolar ridge regions (a, b).
case_images: CRID2019-6895481.001.jpg
case_images: PMC6875186_01_CRID2019-6895481.001.jpg
case_images: fig1
case_images: The intraoral physical examination revealed diffuse, friable, vegetative areas on the right upper alveolar ridge, hard palate, and left inferior alveolar ridge (Figures 1(a) and 1(b)).
case_images: Connective tissue with intense inflammatory infiltrate with a granulomatous pattern, consisting of giant multinucleated inflammatory cells and vacuolated macrophages, with several fungi suggestive of H. capsulatum:(hematoxylin-eosin stain; (a) x200, (b) x400). In (c) and (d), the periodic acid-Schiff (PAS) staining showed vacuolated macrophage with positivity for H. capsulatum ((c d) x400). Note the numerous small rosy dots (arrow).
case_images: CRID2019-6895481.002.jpg
case_images: PMC6875186_01_CRID2019-6895481.002.jpg
case_images: fig2
case_images: An incisional biopsy of the right upper alveolar ridge showed connective tissue with intense inflammatory infiltrate with a granulomatous pattern, consisting of giant multinucleated inflammatory cells and vacuolated macrophages, with innumerable fungi suggestive of H. capsulatum (Figures 2(a) and 2(b)). Staining slides with periodic acid-Schiff (PAS) (Figures 2(c) and 2(d)) and Grocott-Gomori methenamine silver were positive for the morphological characteristics of H. capsulatum.
case_images: After twelve months, the clinical regression of oral histoplasmosis lesions.
case_images: CRID2019-6895481.003.jpg
case_images: PMC6875186_01_CRID2019-6895481.003.jpg
case_images: fig3
case_images: The clinical control one year after initiation of itraconazole treatment can be seen in Figures 3(a) and 3(b).