case_images: PMC10373902_01
case_images: A 53-year-old female patient presenting with "bumpy neck skin." (A) Front and (B) orthogonal view with magnified inset showing raised, hypopigmented bumps characteristic of Birt-Hogg-Dube syndrome.
case_images: ojad064f1.jpg
case_images: PMC10373902_01_ojad064f1.jpg
case_images: ojad064-F1
case_images: The skin of the face, neck (Figure 1A, B), and abdomen (Figure 2) was covered with numerous skin-colored 2 to 8 mm-diameter papules that were occasionally itchy. Tong et al In addition, several acrochordons were observed on the neck and upper chest of this patient (Figures 1B, 2). This "lumpy bumpy" appearance, especially of the neck, has always been embarrassing for the patient.
case_images: Photograph of the abdomen of the 53-year-old female patient shown in Figure 1, revealing many skin growths of different sizes and pigmentations.
case_images: ojad064f2.jpg
case_images: PMC10373902_01_ojad064f2.jpg
case_images: ojad064-F2
case_images: The skin of the face, neck (Figure 1A, B), and abdomen (Figure 2) was covered with numerous skin-colored 2 to 8 mm-diameter papules that were occasionally itchy. Tong et al In addition, several acrochordons were observed on the neck and upper chest of this patient (Figures 1B, 2). This "lumpy bumpy" appearance, especially of the neck, has always been embarrassing for the patient.
case_images: Hematoxylin and eosin stains from the biopsied tissue reveal fibrofolliculomas characterized by the presence of a dilated central follicle, loose connective tissue, and a central cyst lined by keratinizing squamous epithelium.
case_images: ojad064f3.jpg
case_images: PMC10373902_01_ojad064f3.jpg
case_images: ojad064-F3
case_images: In this case, the central cystic space is filled with keratinous debris and lined by keratinizing squamous epithelium that resembles normal epidermis (Figure 3).