case_images: PMC3919951_01
case_images: Axial and coronal views from computed tomography scan revealing the position of the tumor protruding into the bladder with an intact surface.
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case_images: PMC3919951_01_OL-07-03-0891-g00.jpg
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case_images: This was confirmed by cystoscopy demonstrating a protruding tumor on the right wall of the bladder with normal mucosa, measuring 2.0x2.0 cm (Fig. 1A and B).
case_images: Histopathological evaluation of the paraganglioma. (A) Paraganglioma composed of dual cell populations arranged in a characteristic nested Zellballen pattern (H&E staining; magnification, x400). (B) Synaptophysin (immunohistochemical stain) confirmed neuroendocrine origin, compatible with paraganglioma (magnification, x400).
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case_images: On histopathological evaluation, the tumor cells were arranged in a nested pattern (Fig. 2A). The histopathological examination showed positive staining for NSE, Syn, CgA and CD56, sustentacular cells stained positive for S-100 and the Ki-67 staining revealed a proliferation index of <2%, compatible with paraganglioma (Fig. 2B).