case_images: PMC2822253_01
case_images: The EGD shows a submucosal tumor with an irregular central umbilication in the gastric antrum.
case_images: jkms-19-145-g001.jpg
case_images: PMC2822253_01_jkms-19-145-g001.jpg
case_images: F1
case_images: On esophagogastroduodenoscopy (EGD), a submucosal mass with an irregular central umbilication was found in the gastric antrum (Fig. 1).
case_images: The abdominal CT reveals a well-demarcated multiseptate cystic mass (arrows) in the gastric antrum.
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case_images: PMC2822253_01_jkms-19-145-g002.jpg
case_images: F2
case_images: Abdominal CT scan revealed a well-demarcated multiseptate cystic mass in the gastric antrum (Fig. 2).
case_images: The submucosal mass consists of oligolocular cystic (arrows) and solid areas without overlying mucosal change (H&E stain, x10).
case_images: jkms-19-145-g003.jpg
case_images: PMC2822253_01_jkms-19-145-g003.jpg
case_images: F3
case_images: Microscopically, the cystic portion was lined by a single layer of flat, cuboidal epithelium and surrounded by smooth muscle layers (Fig. 3, arrow and Fig. 4A).
case_images: The cystic area (arrows in Fig. 3) shows dilated benign ductal structures lined by cuboidal epithelium (A, H&E stain, x200) and focal periductal glandular structures without islet cell islands (B, H&E stain, x100).
case_images: jkms-19-145-g004.jpg
case_images: PMC2822253_01_jkms-19-145-g004.jpg
case_images: F4
case_images: Periductal glandular structures were focally identified without islet cells (Fig. 4B).
case_images: The solid area shows well to moderately differentiated adenocarcinoma with an adjacent dysplastic change in the lining cells of the dilated ductal structures (H&E stain, x40).
case_images: jkms-19-145-g005.jpg
case_images: PMC2822253_01_jkms-19-145-g005.jpg
case_images: F5
case_images: In the solid area, the adenocarcinoma components forming well-formed tubules (Fig. 5) infiltrated the underlying proper muscle layer and the overlying mucosa of the stomach. A dysplastic change was found in the epithelium of the cystic portion of the heterotopic pancreas, adjacent to the invasive adenocarcinoma (Fig. 5).
case_images: Positive immunoreactivity for cytokeratin 7 is observed in the tumor cells and ductal epithelium in the heterotopic pancreas (x40).
case_images: jkms-19-145-g006.jpg
case_images: PMC2822253_01_jkms-19-145-g006.jpg
case_images: F6
case_images: The neoplastic cells and the heterotopic pancreas tissue showed diffusely strong positivity for cytokeratin 7 (CK7+, 1:200, DAKO, Denmark) and negativity for cytokeratin 20 (CK20-, 1:200, DAKO, Denmark) by immunohistochemical stainings (Fig. 6).