case_images: PMC3687196_01
case_images: Intraoral view showing buccal cortical expansion with ulceration on the palatal aspect
case_images: JOMFP-17-89-g001.jpg
case_images: PMC3687196_01_JOMFP-17-89-g001.jpg
case_images: F1
case_images: The premolars were slightly displaced and an ulcer was observed in the interdental region on the palatal aspect [Figure 1].
case_images: Orthopantomogram showing ill-defined radiolucent lesion i.r.t. right maxillary posterior region with displaced roots of the regional teeth
case_images: JOMFP-17-89-g002.jpg
case_images: PMC3687196_01_JOMFP-17-89-g002.jpg
case_images: F2
case_images: Orthopantomogram revealed a well-delineated, unilocular radiolucent lesion extending from the mesial aspect of 23-26 with divergence of roots of the regional teeth [Figure 2].
case_images: H and E stained section showing islands of clear cells in fibrous connective tissue stroma (x40)
case_images: JOMFP-17-89-g003.jpg
case_images: PMC3687196_01_JOMFP-17-89-g003.jpg
case_images: F3
case_images: Microscopically, sections stained with H and E revealed sheets and islands of large clear cells separated by a delicate fibrous connective tissue stroma [Figure 3].
case_images: H and E stained section showing islands of polygonal, clear cells with interspersed hyperchromatic, columnar cells having eosinophilic cytoplasm (x100), Inset: Nuclear palisading observed at the periphery of the island (x400)
case_images: JOMFP-17-89-g004.jpg
case_images: PMC3687196_01_JOMFP-17-89-g004.jpg
case_images: F4
case_images: In addition, the fibrous connective tissue stroma exhibited some areas of hyalinization, but no fibrous capsule was identified at the periphery of the tumor [Figure 4].
case_images: PAS-positive cytoplasmic granules. Inset: diastase sensitive granules (x400)
case_images: JOMFP-17-89-g005.jpg
case_images: PMC3687196_01_JOMFP-17-89-g005.jpg
case_images: F5
case_images: The abundant cytoplasm of the clear cells showed diastase sensitive Periodic Acid Schiff-positive granules, indicating intracytoplasmic glycogen deposition [Figure 5].
case_images: Mild cytokeratin (CK-8) immunoreactivity in the tumor islands (x400)
case_images: JOMFP-17-89-g006.jpg
case_images: PMC3687196_01_JOMFP-17-89-g006.jpg
case_images: F6
case_images: CK-8 [Figure 6]. CK-19 on the other hand showed moderate, diffuse, heterogeneous pattern of immunoreactivity in the tumor islands [Figure 7].
case_images: Moderate cytokeratin (CK-19) immunoreactivity (x400)
case_images: JOMFP-17-89-g007.jpg
case_images: PMC3687196_01_JOMFP-17-89-g007.jpg
case_images: F7
case_images: CK-8 [Figure 6]. CK-19 on the other hand showed moderate, diffuse, heterogeneous pattern of immunoreactivity in the tumor islands [Figure 7].
case_images: Vimentin immunoreactivity localized to the fibrous connective tissue stroma (x400)
case_images: JOMFP-17-89-g008.jpg
case_images: PMC3687196_01_JOMFP-17-89-g008.jpg
case_images: F8
case_images: Vimentin was strongly positive in the fibrous stromal component only [Figure 8].