case_images: PMC6666353_01
case_images: MRI images (a) Axial T1WI shows heterogeneous signal intensity tumor in the right side of the posterior fossa, mainly iso-to slightly low signal intensity, with multiple round-like low signal intensity regions. The masses have well-defined margins, the right cerebellar hemisphere and vermis are involved, the fourth ventricle and brain stem are compressed and deformed. (b) Axial T2WI shows that the tumor appears as iso-to slightly high signal intensity, with multiple round-like high signal intensity regions. Contrast enhanced MRI. (c) Axial contrast enhanced MRI shows that the mass had obvious heterogeneous enhancement with peritumoral edema and non-enhancement regions of multiple small round cystic lesions and necrosis. (d) Sagittal enhanced image shows that the fourth ventricle was not clear and the contours of enhanced cauliflower-like masses. (e) Axial enhanced image of enhanced FLAIR sequence shows multiple non-enhanced cystic lesions and necrosis more clearly
case_images: TPA-54-125-g001.jpg
case_images: PMC6666353_01_TPA-54-125-g001.jpg
case_images: F1
case_images: Magnetic Resonance Imaging (MRI): Non-enhancement MRI (Figure 1a, b) showed a heterogeneous signal intensity mass in the right side of the posterior fossa. Contrast-enhanced MRI scan (Figure 1c-e): The mass showed obvious heterogeneous enhancement, with multiple cystic regions.
case_images: Microscopic examinations of the tumor show many primitive neural tube, choroidea, squamous epithelium, appendix organ of skin, cartilage, bone, columnar epithelium, and muscle tissues
case_images: TPA-54-125-g002.jpg
case_images: PMC6666353_01_TPA-54-125-g002.jpg
case_images: F2
case_images: Immature teratoma [World Health Organization (WHO) grade III, posterior fossa], contained multiple primitive neural tubes, choroidea, squamous epithelium, appendix organs of skin, cartilage, bone, columnar epithelium, and muscle tissues (Figure 2). Immunohistochemistry: CK (+), EMA (+), 10% Ki67 (+), Syn (+), NF (+), GFAP (+), sporadic LCA (+), some desmin (+).