case_images: PMC11810811_01
case_images: 3D-reconstructed MRCP demonstrates smooth narrowing of the common hepatic duct (solid white arrow), mild focal narrowing at the origins of the right hepatic duct (dashed arrow) and left hepatic duct (yellow arrow). 3D, three-dimensional; MRCP, magnetic resonance cholangiopancreatography.
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case_images: PMC11810811_01_JPR3-6-56-g003.jpg
case_images: jpr312155-fig-0001
case_images: Magnetic resonance cholangiopancreatography (MRCP) showed cholelithiasis and nonspecific narrowing of the common hepatic duct thought to be related to crossing of the hepatic artery without dilatation of the biliary tree (Figure 1).
case_images: There is significant hepatocyte injury, including degenerating hepatocytes and ballooned hepatocytes (dark arrow). Regenerating hepatocytes with multiple nuclei are also noted (open arrow).
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case_images: PMC11810811_01_JPR3-6-56-g002.jpg
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case_images: AUS-guided liver biopsy showed acute and subacute hepatopathy (Figure 2), which was thought to be secondary to Deferasirox.
case_images: Graph of AST/ALT, direct bilirubin, total bilirubin, Alk Phos, and GGT from admission to 6 months post-discharge. ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyltransferase.
case_images: JPR3-6-56-g001.jpg
case_images: PMC11810811_01_JPR3-6-56-g001.jpg
case_images: jpr312155-fig-0003
case_images: Six months after discontinuation, his liver labs were close to normal with DB 0.62 mg/dL (0-0.3 mg/dL) and TB 5.17 mg/dL (0-1.20 mg/dL) with his AST/ALT 49 U/L (8-60 U/L)/33 U/L (0-41 U/L) (see Figure 3).