case_images: PMC11798950_01
case_images: (A) D+26: maculopapular facial rash. (B) D+27: progression of rash over 80% BSA; blistering rash with involvement of mouth and genital mucosa; injected sclera with blurry vision; skin biopsy confirmed pathologic Grade III aGVHD. (C, D) D+34: bullae slowly ruptured, skin peeled, and the patient was left with erythematous skin to the face, chest, back, and extremities.
case_images: fimmu-15-1452245-g001.jpg
case_images: PMC11798950_01_fimmu-15-1452245-g001.jpg
case_images: f1
case_images: Three days later (D+26), he was found to have a maculopapular facial rash, which rapidly progressed over 24 h to involve approximately 80% of his total BSA with skin detachment >30% BSA ( Figure 1A ). The progression was notable for development of vesicles coalescing into bullae and for mucosal involvement of his mouth, eyes, scrotum, and urethra ( Figure 1B ). Over the next 2 days, the bullae slowly ruptured, the skin peeled, and the patient was left with erythematous skin on D+34 ( Figures 1C, D ).