case_images: PMC9626822_01
case_images: A timeline showing symptoms and exams/interventions performed on the patient. AOSD, Adult-onset Still's disease; CRP, C-reactive protein; LDH, lactate dehydrogenase, ESR, erythrocyte sedimentation rate.
case_images: fneur-13-1016393-g0001.jpg
case_images: PMC9626822_01_fneur-13-1016393-g0001.jpg
case_images: F1
case_images: The lymph node ultrasound revealed extensive enlarged superficial lymph nodes (Figure 1). We performed the electrophysiological examination, and nerve and muscle biopsy revealed immune-mediated extensive peripheral nerve injury (Supplementary Figures 1-3).
case_images: Patient's photograph of the sural nerve biopsy specimen. Electron microscopic findings: Myelinated nerve fibers were extensively destroyed. Wallerian degeneration could be observed (white star), and Schwann cells and macrophages were not observed. Scale bars: 2mum.
case_images: fneur-13-1016393-g0002.jpg
case_images: PMC9626822_01_fneur-13-1016393-g0002.jpg
case_images: F2
case_images: We performed the electrophysiological examination, and nerve and muscle biopsy revealed immune-mediated extensive peripheral nerve injury (Supplementary Figures 1-3). Intriguingly, electron microscopy images of nerve biopsy demonstrate the typical manifestation of distal axonal degeneration due to nerve injury:Wallerian degeneration (Figure 2).