case_images: PMC6714328_01
case_images: Histopathological findings in a kidney biopsy specimen showing collapse of capillary loop and segmental sclerosis with proliferation of glomerular epithelial cells. (a) Hematoxylin-eosin staining, high magnification. Intraluminal cell proliferation or necrotizing crescentic formation is not shown. (b) Periodic acid-Schiff staining, high magnification. Mesangial matrix proliferation or mesangial cell proliferation is not shown. (c) Periodic acid-methenamine-silver staining, low magnification. (d) Periodic acid-methenamine-silver staining, high magnification. A segmental lesion is observed at the tubular pole. (e) Periodic acid-methenamine-silver staining, low magnification. (f) Periodic acid-Schiff staining. Although there was slight lymphocytic infiltration in the tubulointerstitial area, obvious tubulointerstitial nephritis was not detected.
case_images: CRIRH2019-1749795.001.jpg
case_images: PMC6714328_01_CRIRH2019-1749795.001.jpg
case_images: fig1
case_images: TIN were not detected in the specimens (Figure 1). There was one glomerulus in the immunofluorescence specimen.
case_images: Patient's clinical course. The patient was treated with PSL and CyA. The urine protein/urine creatinine ratio gradually decreased until complete remission (urine protein excretion <0.3 g/gCr) was achieved. CyA: cyclosporine; PSL: prednisolone.
case_images: CRIRH2019-1749795.002.jpg
case_images: PMC6714328_01_CRIRH2019-1749795.002.jpg
case_images: fig2
case_images: The urinary protein/urinary creatinine ratio was 0.09 g/g Cr, her serum albumin level increased to 3.7 g/dL, and her leg edema disappeared (Figure 2).