case_images: PMC10866087_01
case_images: Core from the renal cortex showing mild interstitial edema and diffuse tubular injury, mostly manifesting as cytoplasmic sub-nuclear vacuoles (hematoxylin and eosin stain, 200x and 400x, respectively).
case_images: cureus-0016-00000052304-i01.jpg
case_images: PMC10866087_01_cureus-0016-00000052304-i01.jpg
case_images: FIG1
case_images: Finally, a kidney biopsy was performed, which showed diffuse tubular vacuolization and focal interstitial edema (Figure 1), while glomeruli only showed evidence of podocyte injury (foot process effacement over 60% of the capillary surface) (Figure 2), possibly suggesting early interstitial nephritis.
case_images: Ultrastructural examination shows effacement of the podocyte foot process, while the glomerular basement membrane has unremarkable thickness and texture (EM).
case_images: cureus-0016-00000052304-i02.jpg
case_images: PMC10866087_01_cureus-0016-00000052304-i02.jpg
case_images: FIG2
case_images: Finally, a kidney biopsy was performed, which showed diffuse tubular vacuolization and focal interstitial edema (Figure 1), while glomeruli only showed evidence of podocyte injury (foot process effacement over 60% of the capillary surface) (Figure 2), possibly suggesting early interstitial nephritis.
case_images: Tubular vacuolization and focal interstitial lymphocytic infiltrate (hematoxylin and eosin stain, 400x).
case_images: cureus-0016-00000052304-i03.jpg
case_images: PMC10866087_01_cureus-0016-00000052304-i03.jpg
case_images: FIG3
case_images: The biopsy showed a similar but less profound tubular injury and focal interstitial lymphocytic infiltrate (Figure 3).