case_images: PMC7520001_01
case_images: (a) Hemotoxylin and eosin (H&E) stain showing enlarged and distended hepatocytes with clear cytoplasm. (b) Periodic acid-Schiff (PAS) stain showing increased glycogen content in the cytoplasm of hepatocytes. (c) Periodic acid-Schiff-diastase (PAS-D) stain showing the removal of glycogen from hepatocytes with the diastase staining.
case_images: CRIPE2020-8836534.001.jpg
case_images: PMC7520001_01_CRIPE2020-8836534.001.jpg
case_images: fig1
case_images: The liver biopsy revealed distended hepatocytes with excessive glycogen accumulation and fine septate fibrosis, and the biopsy of the right vastus lateralis muscle revealed uneven distribution of mitochondria in muscle fibers as well as focal swollen glycogen containing mitochondria (Figure 1).