case_images: PMC3959423_01
case_images: Upper endoscopy showing rings in the middle third of the esophagus (white arrow). Black arrow shows mucosal split at the lower end during endoscopy
case_images: AnnGastroenterol-25-355-g001.jpg
case_images: PMC3959423_01_AnnGastroenterol-25-355-g001.jpg
case_images: F1
case_images: A later endoscopy showed a tight distal stricture and course rings at the middle third of the esophagus (Fig. 1). A mucosal split occurred during endoscopy (Fig. 1, black arrow).
case_images: HE stains showing infiltration of large number of intraepithelial lymphocytes in the peripapillary area without or rare granulocytes
case_images: AnnGastroenterol-25-355-g002.jpg
case_images: PMC3959423_01_AnnGastroenterol-25-355-g002.jpg
case_images: F2
case_images: Biopsies taken from the middle third of the esophagus showed marked infiltration of exclusive intraepithelial lymphocytes in a peripapillary distribution (Fig. 2).
case_images: Immunostains showing presence of CD3 cells (T cells)
case_images: AnnGastroenterol-25-355-g003.jpg
case_images: PMC3959423_01_AnnGastroenterol-25-355-g003.jpg
case_images: F3
case_images: The immunostains showed presence of CD3 and CD5 lymphocytes (T cell markers) in the epithelium (Fig. 3).