case_images: PMC5102841_01
case_images: Chart summarizing the vital signs of the patient with anaphylaxis. Arrows indicate drug administrations: the first narrow arrow, 450 mg of pentothal sodium, 60 mg of rocuronium, and 50 microg of fentanyl; the second narrow arrow, 50 microg of fentanyl; arrowhead, palonosetron; and wide arrow, 5 mg of ephedrine twice, followed by 10 mg of ephedrine twice. Circle indicates the appearance of rash, facial edema, and conjunctival swelling with immediate administration of 4 mg of chlorpheniramine and 100 mg of hydrocortisone. sBP, systolic blood pressure; dBP, diastolic blood pressure.
case_images: aair-9-92-g002.jpg
case_images: PMC5102841_01_aair-9-92-g002.jpg
case_images: F2
case_images: As shown in Fig. 2, for general anesthesia, rocuronium, fentanyl, and sodium pentothal were administered for intubation, and desflurane was used for maintenance.
case_images: Skin test to determine hypersensitivity to palonosetron at dilutions of 1:1, 1:10, 1:100, and 1:1,000. H, control (histamine); N, control (saline). On POD 54, the sizes of wheals were as follows: histamine, 9.5 mm; saline, 2 mm; palonosetron 1:1, 13.86 mm; palonosetron 1:10, 8.5 mm; palonosetron 1:100, 9.5 mm; and palonosetron, 1:1,000, no wheal.. POD, postoperative day.
case_images: aair-9-92-g003.jpg
case_images: PMC5102841_01_aair-9-92-g003.jpg
case_images: F3
case_images: The skin test was negative on days 1 and 17, but was positive at 1:100 dilution of the allergen (0.5 microg/mL) on day 54 (Fig. 3).