case_images: PMC8512258_01
case_images: Chest X-Ray showed a pulmonary nodule (arrow) in the right lower lobe that
  measured 29 x 21 mm without any other lesions.
case_images: 10.1177_2632010X211051741-fig1.jpg
case_images: PMC8512258_01_10.1177_2632010X211051741-fig1.jpg
case_images: fig1-2632010X211051741
case_images: A chest X-Ray showed a pulmonary nodule in the right lower lobe that measured 29 x 21 mm (Figure 1).
case_images: Computed tomography (CT) scan of the chest with a pulmonary nodule
  (25.53 x 20.44 mm) located in the superior segment of the right inferior
  lobe adjacent to the pleura.
case_images: 10.1177_2632010X211051741-fig2.jpg
case_images: PMC8512258_01_10.1177_2632010X211051741-fig2.jpg
case_images: fig2-2632010X211051741
case_images: Subsequent computed tomography (CT) scan of the chest confirmed the pulmonary nodule (25.5 x 20.4 mm) located in the superior segment of the right inferior lobe (Figure 2).
case_images: Lower right lobe of the lung. Black arrow showing the tumor.
case_images: 10.1177_2632010X211051741-fig3.jpg
case_images: PMC8512258_01_10.1177_2632010X211051741-fig3.jpg
case_images: fig3-2632010X211051741
case_images: The patient was cleared for surgery and a right lower lobectomy via thoracotomy was performed (Figure 3).
case_images: Histologic findings of lung tumor: (A) H&E stained sections at low power
  (5x) show organoid nests of large neoplastic cells, (B and C) geographic
  necrosis marked with an * (10x), (D) at high power (40x) neoplasic cells
  contain abundant eosinophilic cytoplasm, granular or salt and pepper
  chromatin pattern with a mitotic account of 36 mitoses per 2 mm2 (arrows),
  and (E-H) immunohistochemistry (40x) shows positive cytoplasmatic staining
  for synaptophysin and CK7, weak and diffuse chromogranin staining, and Ki67
  was highly expressed (70%).
case_images: 10.1177_2632010X211051741-fig4.jpg
case_images: PMC8512258_01_10.1177_2632010X211051741-fig4.jpg
case_images: fig4-2632010X211051741
case_images: Histologically, the tumor showed nests and sheets of monomorphic neoplastic cells, arranged in trabecular and organoid pattern in some fields (Figure 4A) with geographic necrosis and scant well-formed rosettes (Figure 4B and C). High mitotic index ratio was also observed with 36 mitoses per 10 high power field (2 mm2) (Figure 4D). Tumoral cells showed weak and diffuse chromogranin positivity and high level Ki67 staining (70%) (Figure 4E-G).