case_images: PMC10803013_01
case_images: a-d Preoperative FLAIR and contrast-enhanced T1-weighted images (upper panel: FLAIR, lower panel: Gd+, right panel: enhanced lesions, left panel: non-enhanced lesion) showing the three lesions, which are highlighted by three arrowheads; yellow arrowhead: lesion (1), blue arrowhead: lesion (2), red arrowhead: lesion (3). The white arrow indicates a lack of continuity between lesions (2) and (3) in a FLAIR image. FLAIR, fluid attenuated inversion recovery; Gd, gadolinium.
case_images: cro-2024-0017-0001-536051_F01.jpg
case_images: PMC10803013_01_cro-2024-0017-0001-536051_F01.jpg
case_images: F1
case_images: The lesions were as follows: (1) a non-enhancing lesion in the anterior part of the right temporal lobe; (2) an enhancing lesion in the right temporal lobe; and (3) the largest enhancing lesion in the right parietal lobe, extending through the corpus callosum to the left parietal lobe (Fig. 1). T2WI and FLAIR images (Fig. 1).
case_images: Photomicrographs showing the pathological characteristics of the three lesions (hematoxylin and eosin stain, all at x20 magnification). a Lesion (1). b Lesion (2). c Lesion (3). Lesions (2) and (3) contain atypical proliferating cells characterized by densely stained and enlarged nuclei. These areas are associated with areas of necrosis and increased microvascularization. Additionally, there is evidence of degeneration due to chemoradiotherapy, including fibrosis, ghost-like cellular changes, and calcifications. There are similar atypical proliferating cells in some regions of lesion (1).
case_images: cro-2024-0017-0001-536051_F02.jpg
case_images: PMC10803013_01_cro-2024-0017-0001-536051_F02.jpg
case_images: F2
case_images: Histopathological examination had revealed proliferation of atypical cells with enlarged hyperchromatic nuclei, accompanied by microvascular proliferation and partial necrosis (Fig. 2). Similar atypical proliferating cells were identified in some regions of lesion (1) (Fig. 2).