case_images: PMC10994700_01
case_images: Inflammatory response during anti-IL-1 therapy. Daily monitoring of blood cell counts (absolute lymphocyte counts (ALC) and platelets), serum c-reactive protein (CRP), ferritin, and liver transaminases (AST and ALT) showed rapid improvement after therapy with methylprednisolone (MP) and intravenous anakinra (in grey shade) was initiated. Anemia and marked elevations of B-type natriuretic (BNP) and soluble IL-2 (sIL-2) also reverted with therapy (data not shown).
case_images: CRIPE2024-9946401.001.jpg
case_images: PMC10994700_01_CRIPE2024-9946401.001.jpg
case_images: fig1
case_images: Notably, during the treatment with IV anakinra, the patient's fevers improved, his liver enzymes and inflammatory markers started to decrease, and there were clinical signs of improvement (Figure 1).