case_images: PMC11326921_01
case_images: Showing the-anti seizure treatment given during the stay in our hospital including ASM and ketogenic diet. Illustrating highest dosage and application period in milligramms/day (mg/d) and grams/day (g/d). Abbreviations: FFA - fenfluramine, TPM - topiramate, PB - phenobarbital, PHT - phenytoin, BRV - brivaracetam, LCM - lacosamide, PER - perampanel, VPA- valproic acid. Anaesthestics used included: esketamin, propofol, diazepam, isoflurane.
case_images: gr1.jpg
case_images: PMC11326921_01_gr1.jpg
case_images: f0005
case_images: Fig. 1 and Fig. 3. After one week of therapy, SE could not be terminated so we decided to try anaesthetics starting with diazepam on day 7. From day 6 to day 18 continuous
case_images: Panel A. Initial EEG upon arrival showing fast ictal activity in the central region and muscle artefacts during a tonic seizure. Panel B. Treatment day 7 - EEG showing periodic sharp-slow-wave/periodic discharges mainly in the frontocentral regions. Panel C. EEG after initiation of FFA showing diffuse slowing. No epileptiform discharges. All EEGs displayed at 7 microV/mm, HFF 70 Hz, LFF 0.5 Hz, 30 mm/sec (millimeters/second).
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case_images: PMC11326921_01_gr2.jpg
case_images: f0010
case_images: EEG changes can be seen in Fig. 2. Even oral feeding could slowly be established but stayed insufficient during the further hospital stay so that a percutaneous endoscopic gastrostomy (PEG) was placed on 13.01.2023.