case_images: PMC5892341_01
case_images: Clinical images of the patient at first visit. a Slit-lamp examination showed a perforation at the center of the cornea. b The Seidel test was positive with fluorescein staining. c Pigments were attached on the anterior lens capsule. d A retroillumination image showed that the anterior capsule was opacified. e An AS-OCT image showed a corneal perforation that reached the corneal endothelial layer.
case_images: cop-0009-0154-g01.jpg
case_images: PMC5892341_01_cop-0009-0154-g01.jpg
case_images: F1
case_images: Slit-lamp examination showed a perforation at the center of the right cornea; leakage of aqueous humor through the perforation was observed (Fig. 1a). The Seidel test, which evaluates aqueous leakage on the cornea using fluorescein, was positive, although the anterior chamber was deep (Fig. 1b). The iris was damaged, and the anterior lens capsule was opacified with pigments (Fig. 1c, d). AS-OCT showed a corneal wound involving the endothelial layer (Fig. 1e).
case_images: Clinical images of the patient on day 3. a Slit-lamp examination showed that folds of Descemet membrane appeared with cell infiltration. b A retroillumination image showed folds of Descemet membrane. c The Seidel test was negative. d AS-OCT image showed that the wound had closed and the endothelial layer had become smooth.
case_images: cop-0009-0154-g02.jpg
case_images: PMC5892341_01_cop-0009-0154-g02.jpg
case_images: F2
case_images: On day 3, folds of Descemet membrane appeared (Fig. 2a, b). Slit-lamp examination and a repeat AS-OCT suggested inner wound closure (Fig. 2c, d).
case_images: Clinical images of the patient on day 26. a Slit-lamp examination showed that cell infiltration had disappeared. b Slight opacification was left at the center of cornea. c AS-OCT showed that the wound had closed and corneal edema had improved. d AS-OCT analysis suggested that the corneal irregularity caused by the wound was small.
case_images: cop-0009-0154-g03.jpg
case_images: PMC5892341_01_cop-0009-0154-g03.jpg
case_images: F3
case_images: The opacification and cell infiltration at the center of the cornea had improved (Fig. 3a, b). AS-OCT showed healing of the corneal wound with reduction in the central corneal thickness to 523 mum (Fig. 3c). The corneal shape analysis suggested that the wound did not affect corneal irregular astigmatism (Fig. 3d).