case_images: PMC6311237_01
case_images: Muscle biopsy: (a) hematoxylin eosin; (b) staining for cytochrome oxidase; (c) Succinate dehydrogenase (SDH) staining; (d) Gomori trichrome stain.
case_images: CRINM2018-8406712.001.jpg
case_images: PMC6311237_01_CRINM2018-8406712.001.jpg
case_images: fig1
case_images: Muscle biopsy revealed myopathic changes with scattered ragged red and blue fibers, as well as COX negative fibers (Figure 1).
case_images: Ultrastructural examination on muscle: (a) and (b) show intra mitochondrial lipid inclusion; (c) mitochondria with transversal orientation to the myofiber; (d) mitochondrial hyperplasia.
case_images: CRINM2018-8406712.002.jpg
case_images: PMC6311237_01_CRINM2018-8406712.002.jpg
case_images: fig2
case_images: Ultrastructural examination on muscle confirmed the mitochondrial alterations with mitochondrial hyperplasia and ring cristae, intramitochondrial lipid inclusion, and mitochondria with transversal orientation to the myofiber (Figure 2).