case_images: PMC10681373_01
case_images: Acute infection course: massive corneal edema with no red eye, no hypopyon, and no pain at the first postoperative day (a); graft failure with corneal edema, corneal melting, and AC involvement 1 week later (b, c); the new clear cornea sutured in place (d) 10 days postoperatively.
case_images: cop-2023-0014-0001-531801_F01.jpg
case_images: PMC10681373_01_cop-2023-0014-0001-531801_F01.jpg
case_images: F1
case_images: The next day at postoperative control, the patient presented with massive corneal edema (Fig. 1a) with no red eye, no hypopyon, and no pain, so that regular postoperative therapy was delivered. AC involvement (Fig. 1c) - led to the suspicion of acute surgery-related exogenous endophthalmitis. A new surgery was planned as follows: the infected sutures were removed and the opacified, edematous graft with severe melting was replaced with a new donor cornea, the partially dislocated scleral fixation IOL was removed, and subtotal vitrectomy was performed (Fig. 1d).
case_images: Three-day-old A. oryzae colonies grown on solid medium: tryptic soy agar (TSA) (a), Candida bromocresol green (BCG) agar (b), Sabouraud agar (c). Mass spectrum profile of A. oryzae using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS) (d).
case_images: cop-2023-0014-0001-531801_F02.jpg
case_images: PMC10681373_01_cop-2023-0014-0001-531801_F02.jpg
case_images: F2
case_images: Therefore, they were inoculated onto blood agar and Sabouraud dextrose agar isolation media with incubation at 29 C and daily observation: very fast colony growth occurred in both AC exudate samples and donor storage medium cultures (Fig. 2a, b, c). Mass spectrum profile was acquired by MALDI-TOF mass spectrometry and identified as A. oryzae by matching against an in-house-implemented database (Fig. 2d).
case_images: Six months follow-up after voriconazole intravitreal injections a clear graft resulted with a BSCVA of 20/100 with +11 = +3.50 x140  (Aphakia).
case_images: cop-2023-0014-0001-531801_F03.jpg
case_images: PMC10681373_01_cop-2023-0014-0001-531801_F03.jpg
case_images: F3
case_images: Six months after intravitreal injections, a clear graft resulted (Fig. 3a) in a BSCVA of 20/100 with +11 = +3.50 x 140 .