case_images: PMC11184617_01
case_images: Pedigree of the family. Squares and circles represent men and women, respectively. Solid symbols represent cancer patients. Roman numerals indicate generations. Arrows point to the cancer patient.I1 had colon cancer at the age of 60. I2 had liver cancer at the age of 71. II3 and II7 had brain tumors at the age of 57 and 39, respectively.
case_images: fonc-14-1382154-g001.jpg
case_images: PMC11184617_01_fonc-14-1382154-g001.jpg
case_images: f1
case_images: The patient also has a daughter who is currently in good health ( Figure 1 ).
case_images: Pathological examination of MPTs. (A) Pathological finding of sigmoid colon cancer. (B) Pathological finding of acute non-lymphocytic leukemia. (C) Pathological finding of urothelial carcinoma. (D) Pathological finding of ascending colon cancer.
case_images: fonc-14-1382154-g002.jpg
case_images: PMC11184617_01_fonc-14-1382154-g002.jpg
case_images: f2
case_images: Postoperative pathological examination showed mucinous adenocarcinoma of the sigmoid colon infiltrating the outer muscular layer, and no cancer was found on both ends of the sigmoid colon ( Figure 2A ). The final diagnosis was acute non-lymphocytic leukemia, M6 type ( Figure 2B ). The pathological examination revealed invasive papillary carcinoma of grade II to III in the deep muscle layer of the left ureter with involvement of blood vessels ( Figure 2C ). The pathological findings revealed tubular adenoma with high to moderate differentiation (adenocarcinoma) ( Figure 2D ), with cancer tissue infiltrating through the mucosal muscle layer into the submucosa, with a measured depth of infiltration of approximately 2.3mm.