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case_images: eCT image showing a solid mass (3.2 cm x 3.1 cm) in the upper pole of the left kidney in 2019: (a) transverse plane and (b) coronal plane.
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case_images: Enhanced computed tomography (eCT) showed the presence of a solid mass (3.2 cm x 3.1 cm) in the dorsal upper pole of the left kidney, with evidence of invasion into the upper renal calyces (Figure 1).
case_images: (a) Ultrasound showing a high echogenic area with internal uneven echo in the upper pole of the left kidney. (b) Ultrasound showing blood flow signal inside the echogenicity.
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case_images: These findings were confirmed by ultrasonography (Figure 2) and enhanced magnetic resonance imaging (MRI) (Figure 3).
case_images: MRI image showing a solid mass in the upper pole of the kidney with long signal in T2WI: (a) transverse plane and (b) coronal plane.
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case_images: These findings were confirmed by ultrasonography (Figure 2) and enhanced magnetic resonance imaging (MRI) (Figure 3).
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case_images: A sizeable cystic kidney with increased compartments was detected in the left abdomen on eCT and MRI scanning in 2023: (a) transverse plane, (b) coronal plane, and (c) T2 scan.
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case_images: Furthermore, metastasis was indicated based on the observed enlargement of the retroperitoneal lymph nodes (Figure 4).
case_images: Postoperative gross morphology of a typical Xp11.2 translocation RCC. (a) Specimen obtained on RN, showing multiple protruding masses. (b) Dissected specimen showing the cystic tumor covering the whole kidney.
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case_images: The patient provided written consent and underwent retroperitoneal lymph node dissection and radical resection of the left carcinoma under general anesthesia (Figure 5).
case_images: Microscopic examination of tumor cells with dense clear or eosinophilic cytoplasm and papillary and solid multilayered architecture. Hematoxylin and eosin (H&E) staining at 100x magnification. (a) Papillary architecture (200x) and (b) psammoma bodies (red arrows) (400x).
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case_images: Immunohistochemical examination of the tumor cells (200x magnification) and FISH. The tumor cells were negative for CA IX (a), CD117 (d), CK7 (e), GATA3 (f), HMB45 (g), and melan-A (h) expression, using the EnVision two-step immunostaining method at a magnification of 200x. Conversely, positive immunostaining was observed for CD10 (c), P504S (i), and PAX8 (j) using the same method and magnification. Additionally, the tumor cells displayed strong nuclear positivity for Cathepsin K (b) using the EnVision two-step method and for TFE3 (k) using the SP method, both at a magnification of 200x. The TFE3 break-apart FISH assay (l) showed split green and red signals, indicating TFE3 gene rearrangement.
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