case_images: PMC2816287_01
case_images: Chest computed tomography shows diffuse micronodules and ground glass opacities in both lung fields.
case_images: jkms-19-901-g001.jpg
case_images: PMC2816287_01_jkms-19-901-g001.jpg
case_images: F1
case_images: During the 3 yr follow-up period, no significant change was found in pulmonary micronodular densities, but occasionally, GGO was found on chest CT with symptoms of dyspnea ATS grade II and fever (Fig. 1).
case_images: Histologic section shows numerous micronodules in the alveolar spaces (H&E, x1).
case_images: jkms-19-901-g002.jpg
case_images: PMC2816287_01_jkms-19-901-g002.jpg
case_images: F2
case_images: Histologic sections showed numerous micronodules in the alveolar spaces (Fig. 2). Mitotic figures were less than 2 per 10 high power fields.
case_images: Microscopically, nodules consist of short spindle cells arranged in ill-defined whorls. The tumor cells have bland nuclear features and eosinophilic cytoplasm (H&E, x200). Inset shows nuclear immunoreactivity for estrogen receptor (x400).
case_images: jkms-19-901-g003.jpg
case_images: PMC2816287_01_jkms-19-901-g003.jpg
case_images: F3
case_images: These nodules consisted of short spindle cells arranged in ill-defined whorls and the neoplastic cells had bland nuclear features and eosinophilic cytoplasm (Fig. 3). Immunohistochemically, these neoplastic cells showed strong nuclear staining for estrogen receptor (Novocastra, Newcastle, U.K., 1:100 dilution) (Fig. 3, inset) and progesterone receptor (Novocastra, 1:40 dilution), and diffuse cytoplasmic staining for CD10 (Novocastra, 1:40 dilution).