case_images: PMC4334324_01
case_images: Mood state of (A) Case 1 and (B) Case 2 throughout the course of the study.. Notes: The severities of depression and manic states were assessed using the MADRS as a depression rating scale and the YMRS as a mania rating scale.. Abbreviations: MADRS, Montgomery-Asberg Depression Rating Scale; YMRS, Young Mania Rating Scale.
case_images: ndt-11-353Fig1.jpg
case_images: PMC4334324_02_ndt-11-353Fig1.jpg
case_images: f1-ndt-11-353
case_images: Figure 1B.
case_images: Correlation of plasma MHPG levels with MADRS (upper) or YMRS (lower) scores in Case 1 (A) and Case 2 (B).. Notes: There was a significant negative correlation between MHPG levels and MADRS scores (Case 1: rho=-0.542, P<0.001; Case 2: rho=-0.488, P<0.001). There was a significant positive correlation between MHPG levels and YMRS scores (Case 1: rho=0.429, P<0.001; Case 2: rho=0.465, P<0.001). Statistical analysis was performed using Spearman's correlation test.. Abbreviations: MADRS, Montgomery-Asberg Depression Rating Scale; MHPG, 3-methoxy-4-hydroxyphenylglycol; YMRS, Young Mania Rating Scale.
case_images: ndt-11-353Fig2.jpg
case_images: PMC4334324_02_ndt-11-353Fig2.jpg
case_images: f2-ndt-11-353
case_images: We also found a significant negative correlation between MADRS scores and plasma MHPG (rho=-0.465, P<0.001) and HVA (rho=-0.381, P<0.001) levels (Figure 2A).
case_images: PMC4334324_02
case_images: Mood state of (A) Case 1 and (B) Case 2 throughout the course of the study.. Notes: The severities of depression and manic states were assessed using the MADRS as a depression rating scale and the YMRS as a mania rating scale.. Abbreviations: MADRS, Montgomery-Asberg Depression Rating Scale; YMRS, Young Mania Rating Scale.
case_images: ndt-11-353Fig1.jpg
case_images: PMC4334324_02_ndt-11-353Fig1.jpg
case_images: f1-ndt-11-353
case_images: Figure 1B.
case_images: Correlation of plasma MHPG levels with MADRS (upper) or YMRS (lower) scores in Case 1 (A) and Case 2 (B).. Notes: There was a significant negative correlation between MHPG levels and MADRS scores (Case 1: rho=-0.542, P<0.001; Case 2: rho=-0.488, P<0.001). There was a significant positive correlation between MHPG levels and YMRS scores (Case 1: rho=0.429, P<0.001; Case 2: rho=0.465, P<0.001). Statistical analysis was performed using Spearman's correlation test.. Abbreviations: MADRS, Montgomery-Asberg Depression Rating Scale; MHPG, 3-methoxy-4-hydroxyphenylglycol; YMRS, Young Mania Rating Scale.
case_images: ndt-11-353Fig2.jpg
case_images: PMC4334324_02_ndt-11-353Fig2.jpg
case_images: f2-ndt-11-353
case_images: We also found a significant negative correlation between MADRS scores and plasma MHPG (rho=-0.465, P<0.001) and HVA (rho=-0.381, P<0.001) levels (Figure 2A).