case_images: PMC7071809_01
case_images: Fungating tumour with active bleeding from the erosion.
case_images: CRIONM2020-5768438.001.jpg
case_images: PMC7071809_01_CRIONM2020-5768438.001.jpg
case_images: fig1
case_images: Five years following the initial diagnosis, she presented with a rapidly enlarging right breast lump with skin erosion and bleeding of 2 weeks duration (Figure 1).
case_images: (a and b) Microscopic analysis showing anastomosing channels of vascular spaces lined by atypical cells with markedly pleomorphic vesicular nuclei and moderate eosinophillic cytoplasm. (c) Diffuse sheets and infiltrating cords of cells, areas of necrosis and blood lakes. (d) Tumour infiltration around the mammary ducts and surrounding fatty tissues.
case_images: CRIONM2020-5768438.002.jpg
case_images: PMC7071809_01_CRIONM2020-5768438.002.jpg
case_images: fig2
case_images: Microscopic analysis of all lesions showed similar features with anastomosing channels of vascular spaces lined by atypical cells with markedly pleomorphic vesicular nuclei and moderate eosinophillic cytoplasm (Figure 2). There was tumour infiltration around the mammary ducts and surrounding fatty tissues (Figure 2).
case_images: Immunohistochemical analyses showing strong and diffuse cytoplasmic and membrane positivity for CD 31 and occasional cytoplasmic and membrane positivity for CD 34. Tumour cells were negative for PanCK., ER, PR, and HER-2.
case_images: CRIONM2020-5768438.003.jpg
case_images: PMC7071809_01_CRIONM2020-5768438.003.jpg
case_images: fig3
case_images: Immunohistochemical analyses showed strong and diffuse cytoplasmic and membrane positivity for CD 31 and occasional cytoplasmic and membrane positivity for CD 34 (Figure 3).