case_images: PMC11806549_01
case_images: Pedigree, symptom, and EEG recording of the probands. (A) Family pedigree of CNKSR2 variation cases (B) EEG results showed the presence of spike and waves. (C) 6 years old Proband II's carpal bones were 4 years old and 6 months old, phalanges were 6 years old and 8 months old
case_images: 13052_2025_1877_Fig1_HTML.jpg
case_images: PMC11806549_01_13052_2025_1877_Fig1_HTML.jpg
case_images: Fig1
case_images: EEG analyses indicated normal background activity with numerous spikes and waves in the bilateral rolandic areas, prominently on the right side (Fig. 1B). Proband II (Fig. 1A) was a 6-year-old boy. EEG recordings during sleep revealed spikes and waves in the bilateral polus frontalis, frontal and right middle posterior temporal areas (Fig. 1B). In addition, the patient showed delayed bone age (Fig. 1C).