case_images: PMC11095596_01
case_images: CT scan showing innumerable pulmonary nodules and irregular nodular opacities throughout the lungs. CT, computed tomography.
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case_images: F1
case_images: The CT scan showed innumerable pulmonary nodules and irregular nodular opacities throughout the lungs, and the majority were stable from prior imaging, but one of which was new in the medial left upper lobe, measuring up to 15 mm (Fig. 1).
case_images: PET scan showing multiple nodules in the left lung exhibiting variable degrees of abnormally increased tracer activity. PET, positron emission tomography.
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case_images: PMC11095596_01_cro-2024-0017-0001-538796_F02.jpg
case_images: F2
case_images: The patient eventually underwent a positron emission tomography scan, which showed multiple nodules in the left lung exhibiting variable degrees of abnormally increased tracer activity, including the new nodule in the medial left upper lobe on the recent CT scan (Fig. 2).
case_images: a Hematoxylin and eosin stain showing pulmonary neuroendocrine cell hyperplasia (x100 magnification). b Immunohistochemical staining showing lesional cells positive for chromogranin.
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case_images: F3
case_images: Immunohistochemical stains for chromogranin and synaptophysin performed on blocks A5 and A6 were positive within the lesional cells of interest, consistent with neuroendocrine hyperplasia/tumorlets (Fig. 3).
case_images: PET scan showing bilateral pulmonary nodules overall similar in size with an uptake similar to or slightly higher than the blood pool. The nodule with the most avid radiotracer is within the superior and medial left lower lobe, measuring up to 15 mm. PET, positron emission tomography.
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case_images: PMC11095596_01_cro-2024-0017-0001-538796_F04.jpg
case_images: F4
case_images: The nodule with the most avid radiotracer uptake was located within the superior and medial left lower lobe, measuring up to 15 mm (Fig. 4).