case_images: PMC10837848_01
case_images: Lymph node biopsy pathology (A) HEx40, (B) HEx400. The stains of the patient's cervical lymph nodes show the characteristic features of histiocytic necrotizing lymphadenitis. Lymphoid follicular hyperplasia is observed, and the structure of the lymph node in the light-stained area is disrupted. Under a high-power view, histiocytic infiltrate with karyorrhectic debris is seen, along with partly histiocytic crescent-shaped nuclei and large immunoblastic cells at the edges of necrotic foci. The box shows a tissue necrosis lesion. Arrows indicate characteristic crescent-shaped nuclei.
case_images: fimmu-14-1279592-g001.jpg
case_images: PMC10837848_01_fimmu-14-1279592-g001.jpg
case_images: f1
case_images: The postoperative pathology showed numerous lympho-histiocytic cells, multiple necrotic areas with marked karyorrhexis and proliferation of distinctive crescentic histiocytes, and a few remaining lymphoid follicles in the surrounding area without neutrophils or eosinophils ( Figure 1 ).
case_images: Immunohistochemical findings of cervical lymph nodes. (A) CD68(+), (B) MPO(+), (C) CD163(+), and (D) CD123(+).
case_images: fimmu-14-1279592-g002.jpg
case_images: PMC10837848_01_fimmu-14-1279592-g002.jpg
case_images: f2
case_images: Immunohistochemistry was positive for lysozyme, CD68, MPO, CD163 and CD123 ( Figure 2 ).