case_images: PMC11723969_01
case_images: Third-degree generation pedigree of the proband (III-3) with spastic paraplegia.
case_images: cureus-0017-00000077256-i01.jpg
case_images: PMC11723969_01_cureus-0017-00000077256-i01.jpg
case_images: FIG1
case_images: The proband, identified as III-3 in Figure 1, was a 36-year-old Filipino male who sought consultation at the clinic for bilateral lower extremity weakness that started at the age of nine. Third-generation pedigree history (Figure 1) reported a strong familial history of spastic paraplegia on the maternal side, including his grandmother (I-2), mother (II-2), and sister (III-1).