case_images: PMC1334206_01
case_images: Lymph node infarction with viable rim of sub capsular lymphoid tissue. (40X, H & E) Inset: Note the cellular outlines of the individual lymphocytes, which have undergone coagulative necrosis. (400X, H&E).
case_images: 1472-6890-5-11-1.jpg
case_images: PMC1334206_01_1472-6890-5-11-1.jpg
case_images: F1
case_images: On microscopy, two of the lymph nodes (including the largest one) showed near total infarction of the parenchyma with preservation of cellular outlines of the lymphocytes (Fig 1).
case_images: Perinodal blood vessels show marked congestion (H&E-40X), and fibrin thrombi (Inset-H&E-100X).
case_images: 1472-6890-5-11-2.jpg
case_images: PMC1334206_01_1472-6890-5-11-2.jpg
case_images: F2
case_images: The medullary vessels showed vascular congestion however the blood vessels in the perinodal adipose tissue showed multiple fibrin thrombi with congestion in some of the vessels (Fig 2).
case_images: CD20 immunohistochemistry highlights the viable subcapsular lymphoid tissue, where as the adjacent infarcted area also shows focal positivity (H&E-200X).
case_images: 1472-6890-5-11-3.jpg
case_images: PMC1334206_01_1472-6890-5-11-3.jpg
case_images: F3
case_images: T-cells. The infarcted tissue showed variable positivity and these markers highlighted few reactive follicles (Fig 3). The uninvolved lymph nodes also showed a normal positivity pattern.