case_images: PMC4655025_01
case_images: Initial gangrene of the lower limb at admission.
case_images: CRIDM2015-576580.002.jpg
case_images: PMC4655025_01_CRIDM2015-576580.002.jpg
case_images: fig2
case_images: These lesions had a necrotic appearance, without granulation tissue, and were covered by purulent exudates (Figure 2).
case_images: Seven days after EBS treatment and standard dressing.
case_images: CRIDM2015-576580.003.jpg
case_images: PMC4655025_01_CRIDM2015-576580.003.jpg
case_images: fig3
case_images: After 7 days of therapy, the wide ulcers of the lower limb started to present some granulation tissue with irregular edges and discrete fibrinous exudate (Figure 3).
case_images: After 2 weeks of EBS treatment and standard dressing.
case_images: CRIDM2015-576580.004.jpg
case_images: PMC4655025_01_CRIDM2015-576580.004.jpg
case_images: fig4
case_images: Following a two-week EBS treatment period, all wide ulcers of the lower limb had improved with remarkable reduction and marked granulation tissue was apparent on the wide ulcers (Figure 4).
case_images: Skin ulcers completely heal after 5 weeks.
case_images: CRIDM2015-576580.005.jpg
case_images: PMC4655025_01_CRIDM2015-576580.005.jpg
case_images: fig5
case_images: EBS treatment, the ulcers on the leg had completely healed (Figure 5) and the patient was able to walk using a walking aid. ESR and CRP consequently decreased to almost normal values.
case_images: PMC4655025_02
case_images: Foot diabetic ulcer at admission.
case_images: CRIDM2015-576580.006.jpg
case_images: PMC4655025_02_CRIDM2015-576580.006.jpg
case_images: fig6
case_images: A skin examination performed at the time of admission showed a foot ulcer of about 2.5 cm involving the fascia, and it was evaluated as grade II according to the Wagner grading system (Figure 6).
case_images: Wound epithelization after 10 days of EBS treatment.
case_images: CRIDM2015-576580.007.jpg
case_images: PMC4655025_02_CRIDM2015-576580.007.jpg
case_images: fig7
case_images:  Figure 7 shows changes in the diabetic ulcer, respectively, after 10 days of treatment.
case_images: Complete diabetic ulcer healing at discharge.
case_images: CRIDM2015-576580.008.jpg
case_images: PMC4655025_02_CRIDM2015-576580.008.jpg
case_images: fig8