case_images: PMC11771172_01
case_images: Multiple well-demarcated blue-grey patches affecting the face and bilateral temples. (A) Right side view, (B) frontal view, (C) left side view.
case_images: CCID-18-235-g0001.jpg
case_images: PMC11771172_01_CCID-18-235-g0001.jpg
case_images: f0001
case_images: On examination, he had multiple well-demarcated blue-gray patches with no secondary changes affecting the central face and the bilateral temples (Figure 1A-C).
case_images: (A) histologically, lesions showed vacuolar basal cell damage of the epidermis and superficial perivascular lymphohistiocytic infiltrate, apart from pigment incontinence. (H&E, X100). (B) pigment incontinence in the superficial dermis is the histopathological hallmark. (H&E, X200).
case_images: CCID-18-235-g0002.jpg
case_images: PMC11771172_01_CCID-18-235-g0002.jpg
case_images: f0002
case_images: The biopsies showed focal vacuolar basal cell damage of the epidermis and superficial perivascular lymphohistiocytic infiltrate in addition to pigment incontinence (Figure 2A and B).
case_images: Significant improvement with after 6 months of therapy with topical tacrolimus 0.1% cream. (A) Right side view, (B) Frontal view, (C) Left side view.
case_images: CCID-18-235-g0003.jpg
case_images: PMC11771172_01_CCID-18-235-g0003.jpg
case_images: f0003
case_images: The patient presented 6 months later with a significant improvement of his skin's hyperpigmentation (Figure 3A-C).