case_images: PMC11806458_01
case_images: Asymptomatic, skin-colored, erythematous infiltrating nodules on the armpits and trunk.
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case_images: Clinical examination revealed asymptomatic, erythematous, infiltrating skin-colored nodules measuring 2 x 3 cm in the axillae and trunk (Figure 1).
case_images: Subcutaneous soft tissue nodule. Resection revealed metastatic adenocarcinoma with single-cell infiltrate involving the skin, consistent with mammary origin, lobular type. (a) Immunohistochemical staining showed positive nuclear staining for estrogen receptors in 50% of the tumor cells, with staining intensity of ++/+++. (b) Negative nuclear staining for progesterone receptors in the tumor cells. (c) Faintly cytoplasmic positive and negative membranous staining for HER2-neu (c-erbB-2) and (d) Hematoxylin and eosin staining.
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case_images: Immunohistochemical staining showed positive nuclear staining for estrogen receptor (ER) in 50% of tumor cells with ++/+++ intensity, negative progesterone receptor (PR) staining, and faint cytoplasmic and negative membranous staining for HER2-neu (c-erbB-2) (Figure 2).
case_images: Computed tomography scan showing a large amount of ascites and pleural effusion, with no evidence of lung metastases.
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case_images: A computed tomography scan revealed a significant accumulation of ascites and pleural effusion, though no lung metastases were identified (Figure 3).