case_images: PMC4887623_01
case_images: Ultrasonography.
case_images: CRIONM2016-7149821.001.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.001.jpg
case_images: fig1
case_images: Abdominopelvic ultrasound showed bilateral complex adnexal masses (Figure 1) as well as moderate ascites.
case_images: CT scan (abdomen and pelvis).
case_images: CRIONM2016-7149821.002.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.002.jpg
case_images: fig2
case_images: CT scan done showed two heterogeneously enhancing solid cystic lesions arising from the adnexae on either side measuring 12 x 9 cm on left and 9.7 x 8.5 cm on right, eccentric asymmetric wall thickening along the right posterolateral wall in the anal canal and rectum for a length of approximately 3-4 cm of maximal thickness 1.3 cm, and multiple hepatic metastatic lesions noted (Figure 2).
case_images: Sigmoidoscopy.
case_images: CRIONM2016-7149821.003.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.003.jpg
case_images: fig3
case_images: Sigmoidoscopy (Figure 3) showed ulceroproliferative growth 1 cm from anal verge from which multiple biopsies were taken.
case_images: Photomicrograph showing neuroendocrine carcinoma involving the rectum.
case_images: CRIONM2016-7149821.004.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.004.jpg
case_images: fig4
case_images: Rectal and ovarian biopsies were consistent with neuroendocrine carcinoma (Figures 4 and 5).
case_images: Photomicrograph showing tumor composed of cells with round to oval nuclei and stippled chromatin.
case_images: CRIONM2016-7149821.005.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.005.jpg
case_images: fig5
case_images: Rectal and ovarian biopsies were consistent with neuroendocrine carcinoma (Figures 4 and 5).
case_images: Tumor cells showing positivity for synaptophysin (immunohistochemistry for synaptophysin, x200).
case_images: CRIONM2016-7149821.006.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.006.jpg
case_images: fig6
case_images: Immunocytochemistry for synaptophysin and chromogranin was positive (Figures 6 and 7) and also immunolabelled as Ki67 antigen positive.
case_images: Tumor cells showing positivity for chromogranin (immunohistochemistry for chromogranin, x200).
case_images: CRIONM2016-7149821.007.jpg
case_images: PMC4887623_01_CRIONM2016-7149821.007.jpg
case_images: fig7
case_images: Immunocytochemistry for synaptophysin and chromogranin was positive (Figures 6 and 7) and also immunolabelled as Ki67 antigen positive.