case_images: PMC10807985_01
case_images: (A) Chest computed tomography scan obtained at the onset of radiation pneumonitis in April 2020. (B) A chest computed tomography scan was obtained when dabrafenib and trametinib combination therapy was initiated in August 2020.
case_images: RCR2-12-e01277-g001.jpg
case_images: PMC10807985_01_RCR2-12-e01277-g001.jpg
case_images: rcr21277-fig-0001
case_images: Subsequently, the patient developed radiation pneumonitis and was started on prednisolone (PSL) at 30 mg/day in April 2020, which was subsequently tapered off (Figures 1A and 2A,B). Additionally, chest radiography revealed consolidation mixed with a large glass shadow in the left upper lung field (Figures 1B and 2C).
case_images: (A) Chest radiography scan obtained at the onset of radiation pneumonitis in April 2020. (B) Chest radiography scan obtained in July 2020. Radiation pneumonitis was improved by prednisolone. (C) Chest radiography scan obtained when the patient was started on dabrafenib and trametinib combination therapy in August 2020. (D) Chest radiography scan obtained in May 2021. As of 35 weeks after initiation of dabrafenib and trametinib combination therapy, the lung tumour shrinkage was maintained without worsening of interstitial pneumonitis.
case_images: RCR2-12-e01277-g003.jpg
case_images: PMC10807985_01_RCR2-12-e01277-g003.jpg
case_images: rcr21277-fig-0002
case_images: Subsequently, the patient developed radiation pneumonitis and was started on prednisolone (PSL) at 30 mg/day in April 2020, which was subsequently tapered off (Figures 1A and 2A,B). Additionally, chest radiography revealed consolidation mixed with a large glass shadow in the left upper lung field (Figures 1B and 2C). As of 35 weeks after initiation of combination therapy with dabrafenib and trametinib, the lung tumour shrinkage was maintained without worsening interstitial pneumonitis or recurrence of brain metastasis (Figure 2D).