case_images: PMC5422747_01
case_images: Electroretinograms (ERGs) of the patient presented in this case report. a Single bright-flash, mixed rod-cone ERG elicited by a 20-J white flash stimulus after 20 min of dark adaption. This showed a negative configuration and an unremarkable oscillatory potential. b ERGs performed according to the International Society for Clinical Electrophysiology of Vision protocol when the patient was 38 years of age. The rod response was non-recordable and the cone response was within normal range. DA, dark adaptation; LA, light adaptation.
case_images: cop-0008-0237-g01.jpg
case_images: PMC5422747_01_cop-0008-0237-g01.jpg
case_images: F1
case_images: The oscillatory potential was unremarkable (Fig. 1a). However, the photopic 3.0 ERG and the 30-Hz flicker with a background light intensity of 25 cd/m2 after 10 min of light adaptation were within normal limits (Fig. 1b).
case_images: Clinical course of the patient presented in this report. a Visual acuity. b Refraction. c Amplitude of the a-wave. d Amplitude of the b-wave. e Implicit time of the a-wave. f Implicit time of the b-wave. g b/a-wave ratio. The oblique line shows the time when the patient resumed attending our hospital.
case_images: cop-0008-0237-g02.jpg
case_images: PMC5422747_01_cop-0008-0237-g02.jpg
case_images: F2
case_images: By 10 years of age, BCVA had increased to 0.8 in the right eye and 0.9 in the left eye, and has remained unchanged thereafter (Fig. 2a). The myopia has progressed (Fig. 2b). The data for the various components of the mixed rod-cone ERG are shown in Figure 2c-g.
case_images: Color fundus photograph and optical coherence tomography (OCT) image of the patient at present. a The fundus photograph of the right eye shows myopic changes but no atrophic changes. b The OCT image of the right eye shows a normal central retinal thickness and retinal lamination.
case_images: cop-0008-0237-g03.jpg
case_images: PMC5422747_01_cop-0008-0237-g03.jpg
case_images: F3
case_images: The fundus shows myopic changes but no atrophic changes (Fig. 3). Central retinal thickness and retinal lamination are normal on spectral-domain optical coherence tomography (Fig. 3).