case_images: PMC11753348_01
case_images: (A) The T2WI sequence, where (1) indicates that the signal intensity of the L4-L5 vertebral body is significantly lower than that of the surrounding vertebrae (white arrow) with disrupted intervertebral disc morphology, and (2) highlights bone destruction at the upper margin of the L5 vertebral body. (B) The contrast-enhanced sequence, with (3) showing a ring-shaped high-signal band around the intervertebral disc and (4) marking the biopsy site. (C) The histopathological biopsy image of the infected intervertebral space, revealing degenerated bone tissue, inflammatory infiltration, and minor necrosis under the microscope. In Figure C, the top image is at 4x magnification, while the bottom image is at 10x magnification.
case_images: fmed-11-1499153-g001.jpg
case_images: PMC11753348_01_fmed-11-1499153-g001.jpg
case_images: fig1
case_images: Post-contrast enhancement sequences demonstrated diffuse high signal intensity in the L4-L5 vertebral bodies and annular high signal in the L4-L5 intervertebral disc, accompanied by significant disc destruction (Figure 1).
case_images: Timeline of diagnosis and treatment.
case_images: fmed-11-1499153-g002.jpg
case_images: PMC11753348_01_fmed-11-1499153-g002.jpg
case_images: fig2
case_images: Candida tropicalis, while sequencing for Mycobacterium tuberculosis DNA was negative. Consequently, the treatment regimen was modified to intravenous voriconazole 200 mg every 12 h for 2 weeks (Figure 2).