case_images: PMC8684417_01
case_images: Axial (A) and sagittal (B) CT scans of the whole abdomen included the pelvis with IV contrast injection demonstrated a large heterogenous enhancing mass, 5.3x6.2 cm in size with internal calcification in the urinary bladder.
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case_images: PMC8684417_01_RRU-13-833-g0001.jpg
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case_images: CT abdomen was done and revealed a large heterogeneous enhancing mass 5.3x6.2 cm in size with internal calcification in the urinary bladder (Figure 1).
case_images: The histological appearance of the urinary bladder melanoma tissue was composed of solid nests and groups of atypical, poorly differentiated, highly mitotically active cells with prominent nucleoli: HE x10 (A); HE x100 (B); HE x400 (C); immunohistochemistry indicating positive reaction to HMB-45 (x100) (D); Melan-A(x100) (E) and S-100 (x100) (F).
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case_images: PMC8684417_01_RRU-13-833-g0002.jpg
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case_images: Hematoxylin and eosin (H&E) staining was performed on tissue sections and S100 (+), HMB-45 (+), and Melan-A (+) were detected by immunohistochemistry (Figure 2).
case_images: Axial (A) and coronal (B) CT scan of the abdomen/pelvis with IV contrast injection, demonstrated a new left cardiophrenic lymph node enlargement.
case_images: RRU-13-833-g0003.jpg
case_images: PMC8684417_01_RRU-13-833-g0003.jpg
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case_images: After a postoperative period of one year, a computerized tomography scan showed new cardiophrenic lymph node enlargement without local recurrence (Figure 3).