case_images: PMC5070207_01
case_images: The fibrocolonoscopy performed in October 2014 showed multiple ulcers on the colonic mucosa.
case_images: esmoopen2015000032f01.jpg
case_images: PMC5070207_01_esmoopen2015000032f01.jpg
case_images: ESMOOPEN2015000032F1
case_images: A full colonoscopy showed erythematous mucosa, loss of normal vascular pattern and multiple ulcers (figure 1).
case_images: CT scan showing a radiological complete response. (A) was taken on 2 September, 2014 and (B) was taken 12 weeks after first dose of ipilimumab, on 5 November, 2014.
case_images: esmoopen2015000032f02.jpg
case_images: PMC5070207_01_esmoopen2015000032f02.jpg
case_images: ESMOOPEN2015000032F2
case_images: During admission a CT scan performed at week 12 post-ipilimumab showed a complete response of metastatic liver disease (figure 2).
case_images: Skin examinations previous and at week 12 after initiation of ipilimumab. We can observe regression in number and size of multiples skin metastases on the left limb and less swelling.
case_images: esmoopen2015000032f03.jpg
case_images: PMC5070207_01_esmoopen2015000032f03.jpg
case_images: ESMOOPEN2015000032F3
case_images: Moreover a skin examination revealed flat blue-pigmented lesions on the left limb (figure 3) that were biopsied, confirming a complete regression of melanoma with presence of melanophages in the dermis.