case_images: PMC3087490_01
case_images: Mass in the axillary tail of the left breast (mammographic image).
case_images: CRIM2011-972168.001.jpg
case_images: PMC3087490_01_CRIM2011-972168.001.jpg
case_images: fig1
case_images: Mammography revealed a smooth bordered opacity with a 1 cm diameter in the axillary tail of the left breast (Figure 1).
case_images: Nests of polygonal cells with eosinophilic cytoplasm divided by fibrous septa (H&E, x40).
case_images: CRIM2011-972168.002.jpg
case_images: PMC3087490_01_CRIM2011-972168.002.jpg
case_images: fig2
case_images: The histological examination revealed polygonal cells with eosinophilic granular cytoplasm, and fibrous septae between the clusters (Figure 2), cells with vesicular nuclei with prominent nucleoles and eosinophilic granular cytoplasms and eosinophilic intracytoplasmic particles surrounded by a clear halo (Figure 3).
case_images: Eosinophilic granular cells with vesicular nuclei, prominent nucleoli, and in addition intracytoplasmic eosinophilic particles surrounded by a clear zone (H&E, x100).
case_images: CRIM2011-972168.003.jpg
case_images: PMC3087490_01_CRIM2011-972168.003.jpg
case_images: fig3
case_images: The histological examination revealed polygonal cells with eosinophilic granular cytoplasm, and fibrous septae between the clusters (Figure 2), cells with vesicular nuclei with prominent nucleoles and eosinophilic granular cytoplasms and eosinophilic intracytoplasmic particles surrounded by a clear halo (Figure 3).
case_images: Tumor cells showing diffuse strong immunostaining for S-100 protein (x40).
case_images: CRIM2011-972168.004.jpg
case_images: PMC3087490_01_CRIM2011-972168.004.jpg
case_images: fig4
case_images: In immunohistochemical examination, S-100 protein (Figure 4), CEA, and vimentin were (+), and cytokeratin was (-) (Figure 5), and these findings led us to the diagnosis of granular cell tumor.
case_images: The lack of GCDFP-15 immunostaining in tumor cells (x40).
case_images: CRIM2011-972168.005.jpg
case_images: PMC3087490_01_CRIM2011-972168.005.jpg
case_images: fig5
case_images: In immunohistochemical examination, S-100 protein (Figure 4), CEA, and vimentin were (+), and cytokeratin was (-) (Figure 5), and these findings led us to the diagnosis of granular cell tumor.