case_images: PMC11309047_01
case_images: Preoperative brain MRI (4 years prior to surgery). T2-weighted axial sections showing extensive and symmetric white matter signal abnormalities including deep gray nuclei especially of the globi pallidi bilaterally, as well as the red and dentate nuclei.
case_images: sfn-2024-0102-0004-538418_F01.jpg
case_images: PMC11309047_01_sfn-2024-0102-0004-538418_F01.jpg
case_images: F1
case_images: There was note of mild cerebellar and cerebral volume loss resulting in some prominence of the ventricular system (shown in Fig. 1).
case_images: Preoperative brain MRI (3 months prior to surgery). T2-weighted coronal section (a) and T2-weighted axial section (b) at the level of the anterior and posterior commissures, showing extensive subcortical supratentorial increased white matter signal involving the subcortical U fibers and the peripheral cerebral white matter. Symmetric hyperintense signal abnormalities involving the globus pallidus (GP), putamen, and caudate nucleus bilaterally.
case_images: sfn-2024-0102-0004-538418_F02.jpg
case_images: PMC11309047_01_sfn-2024-0102-0004-538418_F02.jpg
case_images: F2
case_images: As was previously seen, there were symmetric T2 and FLAIR hyperintense signal abnormalities involving the globi pallidi, putamen, caudate, dentate, and red nuclei (shown in Fig. 2).
case_images: Postoperative brain MRI. T2-weighted coronal section (a) and T2-weighted axial section (b) at the level of the anterior and posterior commissures, showing the tips of DBS leads implanted in the GP internus bilaterally. c Processed 3D image (Lead-DBS ) showing the DBS leads reaching the GP internus (green) with the volume of tissue activated (red) based on the last stimulation parameters.
case_images: sfn-2024-0102-0004-538418_F03.jpg
case_images: PMC11309047_01_sfn-2024-0102-0004-538418_F03.jpg
case_images: F3
case_images: A postoperative brain MRI confirmed the position of the DBS leads in the intended target (shown in Fig. 3).