case_images: PMC7756053_01
case_images: Disease course of the patient. MRI, Magnetic resonance imaging; OB, oligoclonal immunoglobulin bands; MS, multiple sclerosis; RRMS, relapsing remitting multiple sclerosis; Anti-NMDAR encephalitis, Anti-N-methyl-D-aspartate receptor encephalitis; Anti-AQP4 ab, Anti-aquaporin 4 antibody; Anti-MOG ab, Anti-myelin oligodendrocyte glycoprotein antibody; anti-NMDAR ab, Anti-N-methyl-D-aspartate receptor antibody.
case_images: fimmu-11-595417-g001.jpg
case_images: PMC7756053_01_fimmu-11-595417-g001.jpg
case_images: f1
case_images: Figure 1  provides a graphical presentation of the case.
case_images: Magnetic resonance imaging findings. MRI performed in July 2012 demonstrated multiple T2 hyperintense lesions (periventricular, juxtacortical, thalamus, basal ganglia, caudex cerebri) (A, B), some of them obtained with gadolinium enhancement [(C), arrowhead]. Repeated MRI in Jan 2020 revealed multiple T2 hyperintense lesions (juxtacortical, periventricular, left brachium pontis), with some lesions appearing as "fried egg sign" (D, E). Some of them with enhancement lesions appeared as "open sing sign" [(F), arrowhead]. MRI in May 2020 exhibited multiple FLAIR hyperintense lesions (periventricular, juxtacortical, left caudex cerebri, left temporal lobe) (G, H), with a left temporal lobe lesion showing gadolinium enhancement [(I), arrowhead]. MRI, Magnetic resonance imaging; FLAIR, fluid attenuated inversion recovery.
case_images: fimmu-11-595417-g002.jpg
case_images: PMC7756053_04_fimmu-11-595417-g002.jpg
case_images: f2
case_images: Figures 2G-I ) and she eventually started treatment in May 2020. Following a methylprednisolone pulse therapy complete remission was reached.
case_images: PMC7756053_02
case_images: Magnetic resonance imaging findings. MRI performed in July 2012 demonstrated multiple T2 hyperintense lesions (periventricular, juxtacortical, thalamus, basal ganglia, caudex cerebri) (A, B), some of them obtained with gadolinium enhancement [(C), arrowhead]. Repeated MRI in Jan 2020 revealed multiple T2 hyperintense lesions (juxtacortical, periventricular, left brachium pontis), with some lesions appearing as "fried egg sign" (D, E). Some of them with enhancement lesions appeared as "open sing sign" [(F), arrowhead]. MRI in May 2020 exhibited multiple FLAIR hyperintense lesions (periventricular, juxtacortical, left caudex cerebri, left temporal lobe) (G, H), with a left temporal lobe lesion showing gadolinium enhancement [(I), arrowhead]. MRI, Magnetic resonance imaging; FLAIR, fluid attenuated inversion recovery.
case_images: fimmu-11-595417-g002.jpg
case_images: PMC7756053_04_fimmu-11-595417-g002.jpg
case_images: f2
case_images: Figures 2G-I ) and she eventually started treatment in May 2020. Following a methylprednisolone pulse therapy complete remission was reached.
case_images: PMC7756053_03
case_images: PMC7756053_04
case_images: Magnetic resonance imaging findings. MRI performed in July 2012 demonstrated multiple T2 hyperintense lesions (periventricular, juxtacortical, thalamus, basal ganglia, caudex cerebri) (A, B), some of them obtained with gadolinium enhancement [(C), arrowhead]. Repeated MRI in Jan 2020 revealed multiple T2 hyperintense lesions (juxtacortical, periventricular, left brachium pontis), with some lesions appearing as "fried egg sign" (D, E). Some of them with enhancement lesions appeared as "open sing sign" [(F), arrowhead]. MRI in May 2020 exhibited multiple FLAIR hyperintense lesions (periventricular, juxtacortical, left caudex cerebri, left temporal lobe) (G, H), with a left temporal lobe lesion showing gadolinium enhancement [(I), arrowhead]. MRI, Magnetic resonance imaging; FLAIR, fluid attenuated inversion recovery.
case_images: fimmu-11-595417-g002.jpg
case_images: PMC7756053_04_fimmu-11-595417-g002.jpg
case_images: f2
case_images: Figures 2G-I ) and she eventually started treatment in May 2020. Following a methylprednisolone pulse therapy complete remission was reached.