case_images: PMC5742908_01
case_images: Fundus photograph of the left eye showing central exudation and intraretinal hemorrhages in the temporal macula.
case_images: CRIOPM2017-2824874.001.jpg
case_images: PMC5742908_01_CRIOPM2017-2824874.001.jpg
case_images: fig1
case_images: Fundus examination of the left eye showed intraretinal hemorrhages and exudation with associated edema centrally (Figure 1).
case_images: Wide-field fluorescein angiography of the left eye highlighting numerous microaneurysms and associated leakage within the macula (a) and peripheral capillary dropout (b).
case_images: CRIOPM2017-2824874.002.jpg
case_images: PMC5742908_01_CRIOPM2017-2824874.002.jpg
case_images: fig2
case_images: Wide-field fluorescein angiography of the left eye revealed central microaneurysms with leakage and capillary nonperfusion peripherally (Figure 2).
case_images: (a) Initial OCT of the macular with intraretinal edema and subretinal fluid. (b) Persistent macular edema despite initial peripheral laser photocoagulation and three intravitreal bevacizumab injections at 3 months. (c) Resolution of central macular edema at 12 months after repeated intravitreal aflibercept injections.
case_images: CRIOPM2017-2824874.003.jpg
case_images: PMC5742908_01_CRIOPM2017-2824874.003.jpg
case_images: fig3
case_images: Spectral domain optical coherence tomography (OCT) initially demonstrated macular edema and subretinal fluid (Figure 3(a)). Despite a series of three monthly intravitreal bevacizumab injections, macular edema persisted at 3 months (Figure 3(b)). Additional focal laser to noncenter involving macular edema was also applied at month 10; however, the improvement of macular edema on OCT was most pronounced following two additional monthly injections of intravitreal aflibercept (Figure 3(c)).