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case_images: (A) The image shows facial patchy brownish-black spots, with several lentil-sized follicular red papules distributed on top. (B) The skin lesion on the posterior area has regressed after treatment.
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case_images: Physical examination revealed no abnormalities in various systems, and dermatological analysis unveiled patchy dark brown plaques on the face, with several green bean-sized follicular red papules on top (Figure 1A). The patient was treated with minocycline 100mg/d orally daily; most of the erythema on the face disappeared, and the bumps dried up after ten days of treatment (Figures 1B, 3B and 4B).
case_images: (A) The image displays hyperkeratosis, with lamellar mixed inflammatory cell infiltration (indicated by black arrows) in the superficial dermis (HE, 40x magnification). (B) The image reveals dense lymphocytic and eosinophilic infiltration (indicated by black arrows) around hair follicles and sebaceous glands, disrupting some structures (HE, 200x magnification).
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case_images: Pathological examination of the skin lesions demonstrated excessive keratinization, patchy mixed inflammatory cell infiltration in the superficial dermis, dense infiltration of lymphocytes, and numerous eosinophils around some hair follicles and sebaceous glands, with partial destruction of structures (Figure 2A and B).
case_images: (A) The lesions are ill-defined, with irregular sheets or clusters of punctate vessels (indicated by black arrows) on a dark red base, covered with a few white scales, and seen as follicular corns. (B) The above dermoscopic manifestations subsided after treatment.
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case_images: Dermoscopic examination showed unclear boundaries of the lesion, irregular patches or clusters of red blood vessels on the dark red base, a few white scales on top, and follicular keratosis (Figure 3A). The patient was treated with minocycline 100mg/d orally daily; most of the erythema on the face disappeared, and the bumps dried up after ten days of treatment (Figures 1B, 3B and 4B).
case_images: (A) A sizeable inflammatory infiltrate in the superficial dermis, consisting of many sparse hyper-reflective cells. Additionally, a hyperreflective inflammatory infiltrate (indicated by red arrows) was observed around specific hair follicles and sebaceous glands. (B) After treatment, the hair follicle and the massive inflammatory cell mass-like infiltration around the hair follicle disappeared.
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case_images: Furthermore, a hyper-reflective inflammatory infiltrate was observed around specific hair follicles and sebaceous glands (Figure 4A). The patient was treated with minocycline 100mg/d orally daily; most of the erythema on the face disappeared, and the bumps dried up after ten days of treatment (Figures 1B, 3B and 4B).