case_images: PMC5421196_01
case_images: Schematic diagram of T2-weighted axial (a) and coronal (b) images revealing a nonenhancing hyperintense lesion in the right mesial temporal lobe. Axial (c) and coronal FLAIR sequences (d) showing a hyperintense lesion in the white matter of the right mesial temporal lobe
case_images: SNI-8-64-g001.jpg
case_images: PMC5421196_01_SNI-8-64-g001.jpg
case_images: F1
case_images: The lesion appeared hyperintense on T2-weighted images [Figure 1a and b]. Fluid-attenuated inversion recovery (FLAIR) sequences delineated a nonspecific hyperintense focus in the right temporal lobe near the gray-white interface [Figure 1c and d].
case_images: Schematic diagram of a 20x magnification of H and E stained specimen revealing polyglucosan bodies (a) and 20x magnification of CA stained pink with periodic-acid Schiff staining (b)
case_images: SNI-8-64-g002.jpg
case_images: PMC5421196_01_SNI-8-64-g002.jpg
case_images: F2
case_images: Permanent section H and E slides [Figure 2a] also demonstrated the presence of numerous polyglucosan bodies, far in excess of those found in the normal aging brain. Periodic-acid Schiff stain highlighted the polyglucosan bodies [Figure 2b], providing a final diagnosis of a dense CA lesion.