case_images: PMC8216391_01
case_images: Lumbar spine magnetic resonance imaging. (A) A sagittal T1 sequence shows diffuse hypointense signal of the lumbo-sacral spine (red arrows). (B) An axial T2W sequence showing bilateral sacroiliitis (right > left; green arrow).
case_images: 10.1177_23247096211026503-fig1.jpg
case_images: PMC8216391_01_10.1177_23247096211026503-fig1.jpg
case_images: fig1-23247096211026503
case_images: Lumbar spine magnetic resonance imaging showed abnormal, diffuse, hypointense bone marrow signaling, and diffuse ankylosis of sacroiliac joints (right > left; Figure 1).
case_images: Histopathology and immunofluorescence of kidney biopsy. (A) Renal biopsy periodic acid-Schiff (PAS) stain, 100x magnification, showing multifocal endarteritis (black arrows) and mesangio-proliferative glomerulonephritis (Blue arrows). (B) Immunofluorescence showing arteriolar and glomerular IgM-kappa dominant deposits (Red arrows) consistent with cryoglobulinemic vasculitis and glomerulonephritis.
case_images: 10.1177_23247096211026503-fig2.jpg
case_images: PMC8216391_01_10.1177_23247096211026503-fig2.jpg
case_images: fig2-23247096211026503
case_images: Acute onset of renal failure which was otherwise unexplainable prompted kidney biopsy, which showed multifocal endarteritis with mild mesangial proliferative glomerulonephritis and IgM-kappa dominant deposits diagnostic of cryoglobulinemic vasculitis and glomerulonephritis (Figure 2).