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case_images: Two irregular erythematous plaques hemangioma on the left anterior chest and on the left upper abdomen. The black arrow indicates the observation area for the dermoscope.
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case_images: The lesions gradually bulged, enlarged, brightened, and developed progressively into elevated erythema plaques (Figure 1). Physical examination revealed two irregular erythematous plaques of approximately 3.0 x 1.8 cm in size on the left anterior chest and 2.6 x 1.4 cm in size on the left upper abdomen (Figure 1).
case_images: Dermoscopy (amplification x33) revealed an intensive vascular network. The black arrow indicates the same landmark for comparative dermoscopic observations.
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case_images: Dermoscopy revealed an intensive vascular network (Figure 2).
case_images: A two-dimensional grayscale diagram before treatment revealed an approximately 1.3x0.9x1.5 cm hemangiomatoid solid mass in the patient's right liver. The white circle indicates the location of the hepatic hemangioma.
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case_images: Indeed, abdominal ultrasound revealed an approximately 1.3 x 0.9 x 1.5 cm hemangiomatoid solid mass in the patient's right liver (Figure 3), and the hemogram showed an abundant blood flow signal in the mass (Figure 4), the diagnosis was consistent with Infantile hepatic hemangioma (IHH).
case_images: The hemogram showed an abundant blood flow signal in the mass before treatment. The white circle indicates the location of the hepatic hemangioma.
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case_images: Indeed, abdominal ultrasound revealed an approximately 1.3 x 0.9 x 1.5 cm hemangiomatoid solid mass in the patient's right liver (Figure 3), and the hemogram showed an abundant blood flow signal in the mass (Figure 4), the diagnosis was consistent with Infantile hepatic hemangioma (IHH).
case_images: After 3 months of treatment, the two-hemangioma lesion became flat. The black arrow indicates the observation area for the dermoscope.
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case_images: After 6 months of treatment, the skin lesion became flat and was significantly reduced in size (Figure 5); dermoscopic features showed a distinct vascular network and fewer capillary branches (Figure 6).
case_images: After 3 months of treatment, the intensive vascular network gradually disappeared. The black arrow indicates the same landmark for comparative dermoscopic observations.
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case_images: After 6 months of treatment, the skin lesion became flat and was significantly reduced in size (Figure 5); dermoscopic features showed a distinct vascular network and fewer capillary branches (Figure 6).
case_images: After 4 months of treatment, the solid mass in the right liver shrank to approximately 0.9x0.9 cm. The white circle indicates the location of the hepatic hemangioma.
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case_images: Two repeat ultrasounds of the patient's abdomen (4 and 7 months after starting the ICZ oral solution) revealed a progressive decrease in the size of the IHH, and the internal blood flow signal disappeared (Figures 7-9); therefore, the treatment was terminated at 9 months.
case_images: The internal blood flow signal disappeared after 4 months of treatment. The white circle indicates the location of the hepatic hemangioma.
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case_images: Two repeat ultrasounds of the patient's abdomen (4 and 7 months after starting the ICZ oral solution) revealed a progressive decrease in the size of the IHH, and the internal blood flow signal disappeared (Figures 7-9); therefore, the treatment was terminated at 9 months.
case_images: By the seventh month of treatment, the mass had shrunk to a 0.5 cm echogenic area. The white circle indicates the location of the hepatic hemangioma.
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case_images: Two repeat ultrasounds of the patient's abdomen (4 and 7 months after starting the ICZ oral solution) revealed a progressive decrease in the size of the IHH, and the internal blood flow signal disappeared (Figures 7-9); therefore, the treatment was terminated at 9 months.
case_images: The last follow-up showed no significant liver abnormalities.
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case_images: A follow-up 2 months later showed that the lesions had almost disappeared, with only residual skin erythema remaining (10 and 11), and ultrasounds showed that the IHH had completely disappeared (Figure 12).