case_images: PMC11114136_01
case_images: Ultrasonography shows mild polyhydramnios and also chorioamniotic membrane separation(CMS).
case_images: IMCRJ-17-487-g0001.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0001.jpg
case_images: f0001
case_images: At 36+5-week gestation, upon transferring to our hospital in preparation for delivery, ultrasound revealed mild polyhydramnios (Amniotic fluid index of 33.5 cm.)(Figure 1), chorioamniotic membrane separation(CMS), and an enlarged fetal gastric bubble (7.2cmx3.0cm) (Figure 2), and the pregnant woman was diagnosed with gestational diabetes (GDM) and suspected fetal digestive tract obstruction by the outpatient obstetrician.  
case_images: Ultrasonography shows an enlarged fetal stomach bubble.
case_images: IMCRJ-17-487-g0002.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0002.jpg
case_images: f0002
case_images: At 36+5-week gestation, upon transferring to our hospital in preparation for delivery, ultrasound revealed mild polyhydramnios (Amniotic fluid index of 33.5 cm.)(Figure 1), chorioamniotic membrane separation(CMS), and an enlarged fetal gastric bubble (7.2cmx3.0cm) (Figure 2), and the pregnant woman was diagnosed with gestational diabetes (GDM) and suspected fetal digestive tract obstruction by the outpatient obstetrician.  
case_images: Absence of skin of both lower legs went along Blaschko's lines over the anteromedial aspect starting from the lower third (of right leg) and upper fourth (of left leg) of the thighs and extending to the dorsal and medial plantar aspects of the feet. The lesions had sharply demarcated borders covered by a brownish-red moist ultrathin translucent membrane, beneath which the vasculature was clearly visible.
case_images: IMCRJ-17-487-g0003.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0003.jpg
case_images: f0003
case_images: On physical examination, the neonate was found tachypnea (with respiration rate of 55/min) and absence of skin along Blaschko's lines over the anteromedial aspect of both lower legs almost symmetrically (Figure 3), and also skin absence on the nasal tip (Figure 4), ears, right neck (Figure 5), the right hip, and mucosa absence in the oral cavity, and totally the skin missing covered about 17% of the whole body surface (Roughly, calves, feet, buttocks, and neck accounted for 10%, 3.5%, 2.5%, and 1% respectively), with scattered blisters.
case_images: Aplasia cutis congenita(ACC) also exists on the nose.
case_images: IMCRJ-17-487-g0004.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0004.jpg
case_images: f0004
case_images: On physical examination, the neonate was found tachypnea (with respiration rate of 55/min) and absence of skin along Blaschko's lines over the anteromedial aspect of both lower legs almost symmetrically (Figure 3), and also skin absence on the nasal tip (Figure 4), ears, right neck (Figure 5), the right hip, and mucosa absence in the oral cavity, and totally the skin missing covered about 17% of the whole body surface (Roughly, calves, feet, buttocks, and neck accounted for 10%, 3.5%, 2.5%, and 1% respectively), with scattered blisters.
case_images: The neonate's external ears were both dysplastic, and aplasia cutis congenita(ACC) also exists on the right neck.
case_images: IMCRJ-17-487-g0005.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0005.jpg
case_images: f0005
case_images: On physical examination, the neonate was found tachypnea (with respiration rate of 55/min) and absence of skin along Blaschko's lines over the anteromedial aspect of both lower legs almost symmetrically (Figure 3), and also skin absence on the nasal tip (Figure 4), ears, right neck (Figure 5), the right hip, and mucosa absence in the oral cavity, and totally the skin missing covered about 17% of the whole body surface (Roughly, calves, feet, buttocks, and neck accounted for 10%, 3.5%, 2.5%, and 1% respectively), with scattered blisters. Moreover, there was bilateral ear maldevelopment (Figure 5).   
case_images: Abdominal X-ray reveals a single gas bubble in a distended stomach with no gas detected in the distal portions, indicating pyloric atresia (PA).
case_images: IMCRJ-17-487-g0006.jpg
case_images: PMC11114136_01_IMCRJ-17-487-g0006.jpg
case_images: f0006
case_images: A subsequent plain abdominal radiograph was performed and it revealed a large gastric air bubble with no gas distally (Figure 6), indicating PA.