case_images: PMC11720992_01
case_images: (A) Microscopy of C. auris at x1000 magnification by an optical microscope with urine centrifugal specimen. (B and C) Phenotypic characterization of C. auris colonies on Sabouraud dextrose agar and Chromagar Candida at 35  C for 3 days.
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case_images: PMC11720992_01_IDR-18-127-g0001.jpg
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case_images: The EXS3000 matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system (Zybio, China) identification revealed the presence of Enterococcus faecium and C. auris in urine (Figure 1), and the serum 1,3-beta-D glucan level was 101 pg/mL, the procalcitonin (PCT) level was 0.22 ng/mL.
case_images: Maximum-likelihood phylogeny analysis of representative C. auris strains. Phylogenetic tree of 14 C. auris strains based on sequences from China. Data of C. auris clade IV and clade V strains were retrieved from the NCBI SRA database. Strains of clade I, II, and III are indicated in red, blue, and purple, respectively.
case_images: IDR-18-127-g0002.jpg
case_images: PMC11720992_01_IDR-18-127-g0002.jpg
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case_images: ITS and D1/D2 regions, we found the isolate belonged to clade I (Figure 2). In vitro susceptibility of C. auris strains to ten antifungal drugs was determined using the Sensititre CMC1JHY panel (Thermo Fisher Scientific, USA) and the AMB microbroth dilution kit (BIO-KONT , Wenzhou, China) based on manufacturer's instructions.