case_images: PMC11131417_01
case_images: Peritoneal tumor in Hedgehog. (A) Mass of mesenchymal origin adhered to the bladder (marks in yellow show two lobes of tumor mass). 1 Jejunum, 2 Seminal vesicle, * shows caudal orientation in image.
case_images: fvets-11-1341815-g001.jpg
case_images: PMC11131417_01_fvets-11-1341815-g001.jpg
case_images: fig1
case_images: A few oval-shaped cells with moderate pleomorphism were observed, meeting nuclear malignancy criteria, such as anisokaryosis, nucleoli, and a nucleus-to-cytoplasm ratio of 1:1 as well as cytoplasmic malignancy criteria, such basophilia (Supplementary Figure S1). From visual and morphological points of view, the presence of two oval, whitish, granular, well-defined, and solid lobes was observed; one was larger than the other (measuring 2.5 cm and 1.5 cm, respectively) (Figure 1).
case_images: Histopathological sample with H-E staining. Mesothelial cells arranged in solid masses. (A) Arrow heads show small cysts covered by neoplastic mesothelial cells, asterisk marks interior of cysts with fluid and detached cells inside (4x magnification). (B) Arrow marks mesothelial cells bordering the cyst (10x magnification).
case_images: fvets-11-1341815-g002.jpg
case_images: PMC11131417_01_fvets-11-1341815-g002.jpg
case_images: fig2
case_images: Some areas presented small cysts filled with serous fluid and were also observed to be covered by flattened or cuboidal mesothelial cells (Figures 2A,B).
case_images: Calretinin-positive IHC sample. (A) IHQ with 4x magnification, arrowheads show cysts surrounded by cells positive for the calretinin marker. (B) Asterisk shows interior of cysts with fluid and detached cells inside, 10x magnification. (C) 40x magnification arrows mark cells labeled with IHQ brown staining.
case_images: fvets-11-1341815-g003.jpg
case_images: PMC11131417_01_fvets-11-1341815-g003.jpg
case_images: fig3
case_images: IHC staining showed evident cytoplasmatic positive immunostaining for the marker calretinin (Figure 3) and mesothelin (Figure 4), but showed no positivity for CK5/6.
case_images: Mesothelin-positive IHC sample. (A) IHQ with 4x magnification, arrowheads show cysts surrounded by cells positive for the mesothelin marker. (B) Asterisk shows interior of cysts with fluid and detached cells inside, 10x magnification. (C) 40x magnification arrows mark cells labeled with IHQ brown staining.
case_images: fvets-11-1341815-g004.jpg
case_images: PMC11131417_01_fvets-11-1341815-g004.jpg
case_images: fig4
case_images: IHC staining showed evident cytoplasmatic positive immunostaining for the marker calretinin (Figure 3) and mesothelin (Figure 4), but showed no positivity for CK5/6.