case_images: PMC11769805_01
case_images: Vegetative plaques with circinate pustular edges on the vulva and thigh. The lesion at the biopsy site on the thigh showed significant exacerbation (A) and lesions on the toe, dorsum pedis (B).
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case_images: Notably, the lesions on her thigh worsened significantly after a biopsy ( Figure 1A ). Upon further inquiry, the patient reported the onset of red plaques and pustular skin lesions on her toe and dorsum pedis approximately 10 months before her presentation ( Figure 1B ).
case_images: Skin biopsy (HE) showing mild epidermal hyperplasia, focal acantholysis, and dermal inflammation with neutrophils, lymphocytes, and eosinophils.
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case_images: Initial histopathological examination revealed mild epidermal hyperplasia and dermal inflammation with infiltration of neutrophils, lymphocytes, and eosinophils ( Figure 2 ).
case_images: Skin biopsy (HE) showing epidermis erosions with extensive infiltrations of neutrophils, eosinophils, and lymphocytes in the superficial and mid-dermis.
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case_images: f3
case_images: Histopathological examination of the thigh biopsy revealed epidermal hyperplasia, epidermis erosions, and extensive infiltration of neutrophils, eosinophils, and lymphocytes in the superficial and mid-dermis ( Figure 3 ).