case_images: PMC8172793_01
case_images: Brain MRI in November 2018 revealed multiple ischemic lesions, white matter degeneration and brain atrophy, including hippocampal atrophy.
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case_images: F1
case_images: One year ago, a brain magnetic resonance image (MRI) scan revealed multiple ischemic lesions, white matter degeneration and encephalatrophy, including hippocampal atrophy (Figure 1).
case_images: Human embryonic kidney 293 cells staining transfected with NR1 and NR1-NR2B subunits by using indirect immunofluorescence. As shown in this figure, the results were positive (200x).
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case_images: PMC8172793_01_fneur-12-656024-g0002.jpg
case_images: F2
case_images: Transfection of human embryonic kidney (HEK) 293 cells with NR1 subunit or NR1-NR2B subunits of NMDAR was performed to test for the presence of NMDAR antibody (Figure 2) and it was confirmed by using a commercial kit (Euroimmune, Germany) with both cell-based assay (CBA) and rat brain immunostaining.
case_images: Brain MRI in September 2019 before treatment showed new scattered foci of T2- FLAIR hyperintensity within the periventricular, deep and subcortical white matter of the frontoparietal lobe and progressive brain atrophy, especially in the hippocampus.
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case_images: PMC8172793_01_fneur-12-656024-g0003.jpg
case_images: F3
case_images: Brain MRI showed new scattered foci of T2-weighted-fluid-attenuated inversion recovery (FLAIR) hyperintensity within the periventricular, deep and subcortical white matter of the frontoparietal lobe without post-contrast enhancement (Figure 3).
case_images: Repeated brain MRI after 2 months of treatment in November 2019 showed the scattered foci of T2-FLAIR hyperintensity disappeared partially.
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case_images: PMC8172793_01_fneur-12-656024-g0004.jpg
case_images: F4
case_images: Repeated brain MRI after 2 months of treatment showed scattered foci of T2-FLAIR hyperintensity disappeared partially (Figure 4).