case_images: PMC11185854_01
case_images: Images of capsule endoscopy showing a small bowel polypoidal lesion with surrounding altered blood (a), double-balloon enteroscopy showing an ulcerated jejunal subepithelial lesion (b), and EUS showing a subepithelial lesion arising from the muscularis propria layer (c).
case_images: crg-2024-0018-0001-538688_F01.jpg
case_images: PMC11185854_01_crg-2024-0018-0001-538688_F01.jpg
case_images: F1
case_images: This showed a large pedunculated polypoidal lesion with surrounding altered blood in the proximal small bowel (shown in Fig. 1a). Antegrade double-balloon enteroscopy demonstrated an ulcerated subepithelial lesion in the proximal jejunum (Fig. 1b). Endoscopic ultrasound (EUS) with a 15-MHz mini-probe demonstrated a heterogenous hypoechoic lobulated mass without calcifications measuring 28 mm by 17 mm in cross-sectional diameter arising from the muscularis propria layer (Fig. 1c).
case_images: Axial computed tomography image of an enhancing proximal jejunal submucosal tumour. The arrows show the location of the lesion.
case_images: crg-2024-0018-0001-538688_F02.jpg
case_images: PMC11185854_01_crg-2024-0018-0001-538688_F02.jpg
case_images: F2
case_images: Abdominal computed tomography (CT) with enteroclysis confirmed an isolated submucosal tumour without any other small bowel lesions nor distant lesions (Fig. 2).
case_images: Microscopic images of a surgically resected specimen showing fascicles of spindle cells with minimal cytologic atypia (haematoxylin and eosin staining, original magnification, x200) (a) and tumour cells diffusely positive for CD117 (c-kit) (immunohistochemistry, original magnification, x100) (b).
case_images: crg-2024-0018-0001-538688_F03.jpg
case_images: PMC11185854_01_crg-2024-0018-0001-538688_F03.jpg
case_images: F3
case_images: Histopathology demonstrated a 4.2 cm unifocal tumour composed of fascicles of spindle cells with minimal cytologic atypia (H&E, orig. mag., x200) (Fig. 3a), with immunohistochemistry showing tumour cells diffusely positive for CD117 (c-kit) (IHC, orig. mag., x100) (Fig. 3b), in keeping with a diagnosis of GIST.