case_images: PMC10859147_01
case_images: Low-power view showing skin and subcutaneous tissue with dermal inflammation (A, B; 4x, 10x). Medium and high-power views showing diffuse infiltration of histiocytes in the dermal collagens, forming granulomas consistent with granulomas annulare (C, D; 20x, 40x).
case_images: cureus-0016-00000052174-i01.jpg
case_images: PMC10859147_01_cureus-0016-00000052174-i01.jpg
case_images: FIG1
case_images: The dermal aggregates of loosely arranged histocytes with central foci of necrobiosis and poorly formed granulomas were consistent with GA (Figure 1).
case_images: IHC for CD68 is diffusely positive in histiocytes (A, 20x). PAS, GMS, and AFB are negative for fungal, bacterial, and tuberculosis (B, C, D; 20x).. IHC = immunohistochemistry; PAH = periodic acid-Schiff; GMS = Grocott methenamine silver; ABF = acid-fast bacilli
case_images: cureus-0016-00000052174-i02.jpg
case_images: PMC10859147_01_cureus-0016-00000052174-i02.jpg
case_images: FIG2
case_images: CD68 immunohistochemistry highlighted the histiocytes, and periodic acid-Schiff, Grocott methenamine silver, and acid-fast bacilli stains were negative for fungal and mycobacterial microorganisms (Figure 2).