case_images: PMC11808407_01
case_images: PMC11808407_02
case_images: Urethral mass.
case_images: fonc-14-1503116-g001.jpg
case_images: PMC11808407_02_fonc-14-1503116-g001.jpg
case_images: f1
case_images: The mass was slightly soft, bled easily upon touch, had unclear boundaries, and poor mobility (see  Figure 1 ).
case_images: MRI.
case_images: fonc-14-1503116-g002.jpg
case_images: PMC11808407_02_fonc-14-1503116-g002.jpg
case_images: f2
case_images: Auxiliary Examination: On May 3rd, 2024, pelvic MRI indicated a cystic shadow in the region below the bladder and the urethra, with a mass lesion inside: urethral diverticulum-like changes with suspected tumorous lesions (see  Figure 2 ).
case_images: Cystoscopy.
case_images: fonc-14-1503116-g003.jpg
case_images: PMC11808407_02_fonc-14-1503116-g003.jpg
case_images: f3
case_images: May 11, 2024, cystoscopy revealed a diverticulum approximately 3x3cm in size located below the left urethra, with cauliflower-like neoplasms inside (see  Figure 3 ). Multiple biopsies of the urethral mass were taken intraoperatively, and the postoperative pathological diagnosis indicated a suspected malignant tumor.
case_images: (gross specimen). *CK(Pan), CK8&18, EMA, CK7, and GATA3 all indicate the presence of epithelial components, consistent with the diagnosis of urothelial carcinoma. p63, p53, Ki-67, and HER2 are used to determine the degree of tumor differentiation, malignancy, growth rate, and prognosis. CK5&6 suggests the presence of tumor cells with basal-like features. CD56 indicates the presence of a small number of NK cells or cells with neuroendocrine features in the sample. CK20, CDX2, CgA, and Syn are used to distinguish the origin of the tumor.).
case_images: fonc-14-1503116-g004.jpg
case_images: PMC11808407_02_fonc-14-1503116-g004.jpg
case_images: f4
case_images: The resected gross specimen showed the tumor located within the urethral diverticulum (see  Figure 4 ).