case_images: PMC3644768_01
case_images: Axial T2 weighted images in first admission (a) second admission (b) and at follow-up (c) Hyperintensity of the posterior limb of internal capsule (white arrow), anterolateral midbrain and anterior pons (thick black arrow) and middle cerebellar peduncle (black arrowhead) are more pronounced in second admission. Splenial hyperintensity was circumscribed in first admission while being more extensive in second admission with partial resolution at follow-up (thin black arrow)
case_images: AIAN-16-106-g002.jpg
case_images: PMC3644768_01_AIAN-16-106-g002.jpg
case_images: F1
case_images: Cerebral MRI revealed symmetrical white matter hyperintensities in FLAIR, T2 and diffusion weighted imaging (DWI) sequences, which were hypointense in T1 images [Figure 1a]. MRI revealed extensive symmetrical T2, FLAIR, and DWI hyperintensities of white matter with prominent changes in internal capsule extending through midbrain and pons to middle cerebellar peduncle simulating the 'wine-glass' Figures appearance [Figures 1b and 2a]. Repeat MRI revealed partial resolution of the white matter hyperintensities [Figures 1c and 2b] whereas AEP was normal.
case_images: Coronal T2 weighted images at second admission (a) and at follow-up at 7 months later. There is symmetrical hyperintensity of the white matter in corticospinal tracts from internal capsule to pons producing 'wine glass' appearance (thick white arrow) which extends to middle cerebellar peduncle (black arrow) along with splenial hyperintensity (thin white arrows) at second admission which resolved significantly at follow-up
case_images: AIAN-16-106-g004.jpg
case_images: PMC3644768_01_AIAN-16-106-g004.jpg
case_images: F2
case_images: MRI revealed extensive symmetrical T2, FLAIR, and DWI hyperintensities of white matter with prominent changes in internal capsule extending through midbrain and pons to middle cerebellar peduncle simulating the 'wine-glass' Figures appearance [Figures 1b and 2a]. Repeat MRI revealed partial resolution of the white matter hyperintensities [Figures 1c and 2b] whereas AEP was normal.