case_images: PMC4435049_01
case_images: Fundus photographs of the left eye of the patient upon presentation at our hospital.. Notes: The photographs revealed multiple areas of confluent necrotizing retinitis and occlusive vasculitis at the posterior pole (A) and the temporal periphery (B) with overlying vitritis consistent with acute retinal necrosis.
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case_images: PMC4435049_01_opth-9-853Fig1.jpg
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case_images: On examination, there were 2+ aqueous cells in the anterior chamber and mutton-fat keratic precipitates, and the following were also observed: 3+ vitreous cells, vasculitis in the temporal arcade, and white patches of retinal necrosis in the temporal part of the posterior pole and peripheral retina (Figure 1).
case_images: Agarose gel electrophoresis of the PCR products from vitreous.. Notes: Positive controls (A) and vitreous sample from the patient (B). Lane 1: HSV-1; lane 2: HSV-2; lane 3: VZV; lane 4: EBV; lane 5: CMV; lane 6: HHV-6A/B; and lane 7: HHV-7. VZV and CMV were detected (B).. Abbreviations: PCR, polymerase chain reaction; HSV, herpes simplex virus; VZV, varicella-zoster virus; EBV, Epstein-Barr virus; CMV, cytomegalovirus; HHV, human herpes virus.
case_images: opth-9-853Fig2.jpg
case_images: PMC4435049_01_opth-9-853Fig2.jpg
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case_images: The results of the PCR of vitreous were positive for VZV and CMV and negative for HSV, EBV, and human herpes virus 6 and 7 (Figure 2).
case_images: Gradual resolution of the retinitis and occlusive vasculitis with treatment.. Notes: Gradual resolution of the retinitis and occlusive vasculitis with treatment (silicon oil in situ): day 2 (A), day 5 (B), day 8 (C), and day 20 (D) after admission to our hospital.
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case_images: PMC4435049_01_opth-9-853Fig3.jpg
case_images: f3-opth-9-853
case_images: Although the patient was given only acyclovir, the white patches gradually disappeared or cicatrized (Figure 3).