case_images: PMC11828631_01
case_images: High-resolution CT scan of the temporal bone showcasing the osteolytic lesion, soft tissue invasion in the middle ear and mastoid.
case_images: cureus-0017-00000077501-i01.jpg
case_images: PMC11828631_01_cureus-0017-00000077501-i01.jpg
case_images: FIG1
case_images: CT and MRI results showed an osteolytic lesion with involvement of the glenoid cavity, middle fossa, and anterior wall of the auditory external canal, with a soft tissue expression to the inner ear (Figures 1, 2). Clinical examination at this time showed exophytic invasion in the outer 1/3 of the external auditory canal.
case_images: MRI of the brain showcasing the lesion with involvement of the middle fossa.
case_images: cureus-0017-00000077501-i02.jpg
case_images: PMC11828631_01_cureus-0017-00000077501-i02.jpg
case_images: FIG2
case_images: CT and MRI results showed an osteolytic lesion with involvement of the glenoid cavity, middle fossa, and anterior wall of the auditory external canal, with a soft tissue expression to the inner ear (Figures 1, 2). Clinical examination at this time showed exophytic invasion in the outer 1/3 of the external auditory canal.
case_images: Histological microscopic images from the lesion biopsy.. A. Immunohistochemistry stain for CDX2 at 100x magnification; B. Immunohistochemistry stain for CK7 at 100x magnification; C. Immunohistochemistry stain for CK20 at 100x magnification; D. Hematoxylin and Eosin stain at 100x magnification
case_images: cureus-0017-00000077501-i03.jpg
case_images: PMC11828631_01_cureus-0017-00000077501-i03.jpg
case_images: FIG3
case_images: Histological analysis revealed invasive adenocarcinoma consistent with colorectal origin (CK20+, CDX2+, CK7-, TTF1-, PSA-) (Figure 3).