case_images: PMC11080743_01
case_images: (A) Verrucous plaques over both sides of the labia majora, with overlying vesicles. (B) Brownish-red pigmentation and induration above the ankles. Notice the overlying dilated veins.
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case_images: The skin of the mons pubis was erythematous and indurated. (Figure 1A). These changes were consistent with lipodermatosclerosis (Figure 1B).
case_images: Dilated lymphatic channels within the papillary dermis. H&E stain 20X.
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case_images: Multiple skin biopsies were taken: Punch biopsy taken from vesicles over labia demonstrated dilated lymphatic channels (Figure 2), while ellipse biopsy taken from indurated skin overlying mons pubis showed non-caseating epithelioid granulomas (Figure 3).
case_images: Non-caseating epithelioid granulomas within the reticular dermis. H&E stain 20X.
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case_images: PMC11080743_01_10.1177_11795476241253109-fig3.jpg
case_images: fig3-11795476241253109
case_images: Multiple skin biopsies were taken: Punch biopsy taken from vesicles over labia demonstrated dilated lymphatic channels (Figure 2), while ellipse biopsy taken from indurated skin overlying mons pubis showed non-caseating epithelioid granulomas (Figure 3).
case_images: Clinical response after 6months of antimalarial therapy and topical steroids.
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case_images: The patient was evaluated monthly, and by the end of the 6 months, she reported a significant improvement in pain and appearance (Figure 4).