case_images: PMC7320889_01
case_images: Inflammation of the anterior dorsal tongue is evident.
case_images: CCIDE-12-219-g0001.jpg
case_images: PMC7320889_01_CCIDE-12-219-g0001.jpg
case_images: F0001
case_images: Erythema was noted of the anterior tongue (Figure 1), approximately two cm in diameter.
case_images: A lesion of the lower right lip is evident.
case_images: CCIDE-12-219-g0002.jpg
case_images: PMC7320889_01_CCIDE-12-219-g0002.jpg
case_images: F0002
case_images: Also, the clinician noted a raised area of the right vermilion of the lip approximately 1.5 cm in diameter of normal coloration and texture (Figure 2).
case_images: Low magnification of the lip specimen reveals intact normal arranged epithelium lining. Directly below are dilated blood vessels in the superficial lamina propria surrounded by sparse lymphocytic infiltrate scattered throughout the area. In the deep reticular zone there are numerous large and small nests of non-caseating granulomatous infiltrate with scattered inflammatory cells.
case_images: CCIDE-12-219-g0003.jpg
case_images: PMC7320889_01_CCIDE-12-219-g0003.jpg
case_images: F0003
case_images: There were numerous large and small nests of non-caseating granulomatous infiltrate consisting of epithelioid histiocytes and scattered inflammatory cells within the deep reticular zone. (Figures 3 and 4) The histologic appearance of the anterior tongue biopsy revealed numerous and extensive lymphocytic inflammation surrounding blood vessels and interlaced between were nests of non-caseating granulomatous infiltration of the reticular zone. (Figure 5) Giant cells were not evident in either site.
case_images: Medium magnification of the lip specimen reveals large and small clustered nest of non-caseating granulomatous infiltrate consisting of epithelioid histiocytes with no giant cells. Scattered chronic inflammation and dilated blood vessels at the superficial lamina propria and surrounding granulomatous nest.
case_images: CCIDE-12-219-g0004.jpg
case_images: PMC7320889_01_CCIDE-12-219-g0004.jpg
case_images: F0004
case_images: There were numerous large and small nests of non-caseating granulomatous infiltrate consisting of epithelioid histiocytes and scattered inflammatory cells within the deep reticular zone. (Figures 3 and 4) The histologic appearance of the anterior tongue biopsy revealed numerous and extensive lymphocytic inflammation surrounding blood vessels and interlaced between were nests of non-caseating granulomatous infiltration of the reticular zone. (Figure 5) Giant cells were not evident in either site.
case_images: Low magnification of anterior tongue specimen reveals numerous and extensive lymphocytic inflammatory response surrounding blood vessels and interlaced between are nests of non-caseating granulomatous infiltration within the reticular zone.
case_images: CCIDE-12-219-g0005.jpg
case_images: PMC7320889_01_CCIDE-12-219-g0005.jpg
case_images: F0005
case_images: There were numerous large and small nests of non-caseating granulomatous infiltrate consisting of epithelioid histiocytes and scattered inflammatory cells within the deep reticular zone. (Figures 3 and 4) The histologic appearance of the anterior tongue biopsy revealed numerous and extensive lymphocytic inflammation surrounding blood vessels and interlaced between were nests of non-caseating granulomatous infiltration of the reticular zone. (Figure 5) Giant cells were not evident in either site.