case_images: PMC10896921_01
case_images: Timeline from amniocentesis to termination of pregnancy due to severe preeclampsia.
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case_images: PMC10896921_01_fmed-11-1340905-g001.jpg
case_images: fig1
case_images: For better comprehension of the course of disease, please have a look at the timeline in Figure 1. For the course of ss HCG levels, see Supplementary Figure S1.
case_images: Ultrasound images showing the hydatidiform mole presenting as an enlarged placenta with numerous cysts reminding of a bunch of grapes.
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case_images: PMC10896921_01_fmed-11-1340905-g002.jpg
case_images: fig2
case_images: In the department of prenatal diagnostics, an ultrasound scan showed a normal fetus and an enlarged, mole-like placenta praevia, keeping with a hydatidiform mole (see Figure 2).
case_images: Histopathology images of the the normal placenta (A) and of the complete hydatidiform mole (B) using haematoxylin eosin staining. The pictures of the hydatitiform mole show a centrally broadened stroma with scarcely cells and pseudocystic transformation. The stroma is surrounded by a markedly proliferating accumulation of syncytio- and cytotrophoblasts. Magnification x5, x10.
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case_images: PMC10896921_01_fmed-11-1340905-g003.jpg
case_images: fig3
case_images: A selection of the histopathological samples is shown in Figure 3.
case_images: Quantitative Fluorescence PCR illustrates the absence of maternal alleles in DNA originating from hydatidiform mole. In molar DNA, only one (paternally inherited) allele could be detected for each STR- marker.
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case_images: PMC10896921_01_fmed-11-1340905-g004.jpg
case_images: fig4
case_images: Figure 4 shows the results of Quantitative Fluorescence PCR illustrating the finding of paternal uniparental isodisomy.