case_images: PMC10601888_01
case_images: Fundus photography showing vascular attenuation and retinal pigment mottling. a Right eye. b Left eye.
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case_images: F1
case_images: Fundoscopic examination showed discrete vascular attenuation with subtle pigment epithelium alterations (Fig. 1).
case_images: OCT scan showing foveal disruption of ellipsoid and interdigitation zone. a Right eye. b Left eye.
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case_images: F2
case_images: OCT scan examination revealed foveal disruption of ellipsoid and interdigitation zone with normal foveal depression in both eyes (Fig. 2).
case_images: Fluorescein angiography. a Early arteriovenous phase (right eye). b Late venous phase (right eye). c Late venous phase (left eye).
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case_images: F3
case_images: Fluorescein angiography showed no signs of retinal vasculitis or other vascular pathology, although minor leakage of dye from the optic disc was noted in the late phase (Fig. 3).
case_images: Octopus perimetry showing general visual field depression in both eyes.
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case_images: F4
case_images: Automated perimetry examination with an Octopus Field Analyzer showed generalized suppression in the right eye (Fig. 4).
case_images: Full-field ERG showing an electronegative ERG reflecting inner retinal dysfunction in the right eye.
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case_images: F5
case_images: Considering her medical history of melanoma in combination with the currently presenting visual phenomena and abnormal visual field examination, further investigation was done using full-field flash ERG (Fig. 5).
case_images: PET-CT scan showing uptake of FDG glucose of the regional distant lymph node at the right-sided iliac lymph node chain, indicated by the arrow.
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case_images: F6
case_images: We subsequently organized a full-body CT and positron emission tomography scan, which showed uptake of fluorodeoxyglucose at the right-sided iliac lymph node chain (Fig. 6).
case_images: Octopus perimetry showing improvement of the visual field defects of both eyes with persisting arcuate scotoma in the upper sector.
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case_images: F7
case_images: Objectively, vision remained, but a marked improvement of the visual field examination was noted, with only a remaining arc scotoma in the superior sector (Fig. 7).
case_images: Full-field ERG after peroral glucocorticoid treatment showing recuperation of b-wave in the right eye.
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case_images: F8
case_images: Posttreatment ERG showed improvement in both eyes with normalization of the b-wave in the right eye (Fig. 8).