case_images: PMC11250046_01
case_images: A 42-years-old male with cystic intracranial solitary fibrous tumor. (A, B) The mass was multicompartmental cystic with hypointensity T1WI and hyperintensity T2WI in the cystic component and equal/slightly hyperintensity T1WI and mixed signal T2WI in the solid component, with surrounding edema, mass effect and compression of the ventriculus quartus cerebri, no obvious destruction of adjacent bone. (C, D) A high signal on diffusion-weighted imaging (DWI), and a low signal on apparent diffusion coefficient (ADC). (E) The enhanced scan showed that the solid component of the lesion and the cystic wall were significantly enhanced. (F) Sagittal view shows the mass growing across the vermis of the cerebellum.
case_images: fonc-14-1422779-g001.jpg
case_images: PMC11250046_01_fonc-14-1422779-g001.jpg
case_images: f1
case_images: Magnetic Resonance Imaging (MRI) Scanning and Enhancement: there was a mass of predominantly cystic composition in the right occipital region, measuring approximately 5.1x5.3x6.0cm, which crossed the cerebellar peduncle, compressed the adjacent brain parenchyma, and the fourth ventricle was narrowed by the compression ( Figure 1F ). The mass was multicompartmental cystic with hypointensity T1WI and hyperintensity T2WI in the cystic component and equal/slightly hyperintensity T1WI and mixed signal T2WI in the solid component ( Figures 1A, B ). Diffusion-weighted imaging (DWI) showed heterogeneous hyperintense with decreased apparent diffusion coefficient (ADC) values ( Figures 1C, D ). The enhanced scan showed that the solid component of the lesion and the cystic wall were significantly enhanced ( Figure 1E ).
case_images: HE stainingx100 and immunohistochemistry. (A) H&E staining revealed the tumor cells are spindle-shaped, diffusely distributed, the density of tumor cells is high, the pathological mitotic image is not obvious in the sparse area, the interstitium is interspersed with collagen fibers, and the vitreous changes can be seen around the blood vessel wall. (B) STAT-6M marker: diffuse strong positive expression of tumor cell nuclei.
case_images: fonc-14-1422779-g002.jpg
case_images: PMC11250046_01_fonc-14-1422779-g002.jpg
case_images: f2
case_images: Pathological analysis confirmed the presence of a solitary fibrous tumor, characterized by histomorphology and immunophenotype ( Figures 2A, B ), including CD34 (+), SATA6 (+), Vimentin (+), and Ki-67 (+, about 3%).