case_images: PMC10879359_01
case_images: Echocardiogram optimizing the right ventricle with the right parasternal short axis view of the right ventricular outflow tract depicting irregular thickening and heterogenous echodensity surrounded by anechoic pericardial effusion. The white outline area is the location depicted in the zoomed insert on the lower left corner, a focused area of the right ventricular free wall base, which depicts the heterogenous echodensity of the myocardium with a hypoechoic, roughly spherical mass (arrow). A, aorta; MPA, main pulmonary artery; PE, pericardial effusion; RA, right atrium; RV, right ventricle; RVW, right ventricular wall.
case_images: fvets-11-1256442-g001.jpg
case_images: PMC10879359_01_fvets-11-1256442-g001.jpg
case_images: fig1
case_images: There was diffusely irregular thickening of the anterior and septal right ventricular walls, which were hyperechoic and mottled in appearance due to heterogenous echogenicity (Figure 1), consistent with infiltration.
case_images: Gross section of the left ventricular outflow tract. Multifocal to coalescing, white to tan, soft nodules expand the myocardium; microscopically, these masses were composed of neoplastic round cells. Adjacent to the aorta root is an oval, red, well-circumscribed nodule (circled by a blue-dashed line), which is histologically consistent with a chemodectoma.
case_images: fvets-11-1256442-g002.jpg
case_images: PMC10879359_01_fvets-11-1256442-g002.jpg
case_images: fig2
case_images: The myocardium of the right and left ventricular free walls was irregularly thickened by numerous multifocal to coalescing, white to tan, soft nodules ranging from 1 mm in diameter to 10x5x3mm (Figure 2). The nuclei were about the size of an erythrocyte, and there were 108 mitotic figures in ten 400x (2.37 mm2) fields, with occasional bizarre mitoses.
case_images: Myocardial lymphoma. (A) Right ventricular outflow tract. The myocardium is multifocally expanded by sheets of neoplastic round cells (H&E stain, 20x). (B) Neoplastic round cells have scattered mitoses (H&E stain, 600x). (C) Immunohistochemistry for CD3; no immunoreactivity (600x). (D) Immunohistochemistry for CD8; no immunoreactivity (600x).
case_images: fvets-11-1256442-g003.jpg
case_images: PMC10879359_01_fvets-11-1256442-g003.jpg
case_images: fig3
case_images: Figures 3, 4 highlight the immunoreactivity of the two tumors.
case_images: Aortic chemodectoma. (A) Mass adjacent to the aorta (bracket) (H&E stain, 40x). (B) Nests and packets of polygonal neoplastic cells with granular basophilic cytoplasm (H&E stain, 400x). (C) Churukian-Schenk stain highlights the argyrophilic (black) neurosecretory granules in the neoplastic cells (H&E stain, 600x). (D) Immunohistochemistry for neuron-specific enolase (NSE). There is faint pink cytoplasmic and membranous immunoreactivity (black arrows indicate some of the immunoreactive cells) (600x). The inset is positive control brain tissue with a large immunoreactive pyramidal neuronal cell body (600x).
case_images: fvets-11-1256442-g004.jpg
case_images: PMC10879359_01_fvets-11-1256442-g004.jpg
case_images: fig4
case_images: Figures 3, 4 highlight the immunoreactivity of the two tumors.