case_images: PMC6390251_01
case_images: PMC6390251_02
case_images: Patient's face shows "bird-like facial appearance", beak-shaped nose, scarce and gray hair, and eyebrows. Note thin upper limbs with decreased subcutaneous fat and truncal obesity.
case_images: CRIG2019-8538325.001.jpg
case_images: PMC6390251_02_CRIG2019-8538325.001.jpg
case_images: fig1
case_images: He had thin upper limbs with decreased subcutaneous fat and truncal obesity (Figure 1).
case_images: Lower limbs with markedly atrophied skin and subcutaneous fat, abnormal pigmentation of the skin and hyperkeratosis in the left perimalleolar area, flat feet, plantar hyperkeratosis, and callus in the right 5th metatarsal head and 5th metatarsal base areas.
case_images: CRIG2019-8538325.002.jpg
case_images: PMC6390251_02_CRIG2019-8538325.002.jpg
case_images: fig2
case_images: Moreover, we found short stature, hypogenitalism, lower limbs with markedly atrophied skin and subcutaneous fat, abnormal pigmentation of the skin and hyperkeratosis, and flat feet (Figures 2 and 3).
case_images: Left foot showing contractures, nail dystrophy, dermal atrophy, circumscribed hyperkeratosis and hyperpigmentation, and decreased subcutaneous fat and muscle.
case_images: CRIG2019-8538325.003.jpg
case_images: PMC6390251_02_CRIG2019-8538325.003.jpg
case_images: fig3
case_images: Moreover, we found short stature, hypogenitalism, lower limbs with markedly atrophied skin and subcutaneous fat, abnormal pigmentation of the skin and hyperkeratosis, and flat feet (Figures 2 and 3).