case_images: PMC9022114_01
case_images: Contrast-enhanced magnetic resonance (MR) of a mass on the pancreatic neck-body. (A) T1W Cross-sections MR in arterial phase. (B) T1W Cross-sections MR in portal phase. (C) T2W Axial MR in arterial phase.
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case_images: PMC9022114_01_fsurg-09-874006-g001.jpg
case_images: F1
case_images: Contrast-enhanced magnetic resonance (MR) revealed an 8.2 x 5.7 cm circular confounding signal mass on the pancreatic neck (Figure 1).
case_images: A slightly weaker echogenic mass on ultrasound. (A) Two-dimensional ultrasonography. (B) contrast-enhanced ultrasound (CEUS) in arterial phase. (C) CEUS in parenchymal phase.
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case_images: F2
case_images: Two-dimensional ultrasonography revealed a slightly weaker echogenic mass of approximately 8.6 x 6.4 cm in the pancreatic neck body area, with clear boundaries, clear capsules, heterogeneous internal echoes, and small hypoechoic areas (Figure 2A). CEUS considered mostly SPT (Figures 2B,C).
case_images: Photomicrograph of pancreatic neurofibroma. Collagen fibers contain a large number of spindle cells (H&E stain, x100).
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case_images: F3
case_images: Histopathology found that the tumor was mainly composed of spindle cells with cytologically bland wavy nuclei in a collagenous matrix (Figure 3).
case_images: Photomicrograph of pancreatic neurofibroma. (A) Immunohistochemical staining [CD34(+)]. (B) Immunohistochemical staining [S100(+)].
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case_images: PMC9022114_01_fsurg-09-874006-g004.jpg
case_images: F4
case_images: CD34 (+), and Ki67 (+2%) (Figures 4A,B). Combined with histological morphology and immunohistochemical results, it was considered a peripheral nerve tumor, and its subtype was consistent with solitary neurofibroma.