case_images: PMC11253907_01
case_images: EEG features of continuous periodic biphasic and triphasic complexes and generalized slow waves.
case_images: autopsy-14-e2024502-g01.jpg
case_images: PMC11253907_01_autopsy-14-e2024502-g01.jpg
case_images: gf01
case_images: On further evaluation, Electroencephalogram (EEG) showed periodic sharp wave discharges bilaterally throughout the EEG recording (Figure 1).
case_images: Brain MRI. A - DWI images (b 1000) at basal ganglia; and B - supraganglionic levels showing cortical hyperintensities (white arrows) in the frontal, parietal, occipital lobes and insular cortex, more predominant on the right side (the 'Cortical Ribbon' sign - white arrows) and also hyperintensity in the pulvinar of thalami (yellow arrow) bilaterally and the right putamen (blue arrow);C and D - FLAIR images at basal ganglia and supraganglionic levels show subtle hyperintensities in the cerebral cortex in the distribution described above and in bilateral pulvinar region. These findings are consistent with sporadic CJD.
case_images: autopsy-14-e2024502-g02.jpg
case_images: PMC11253907_01_autopsy-14-e2024502-g02.jpg
case_images: gf02
case_images: Changes were more widespread and prominent on the right side, with corresponding appreciable cortical FLAIR hyperintensity seen in most of these areas, representing the classical cortical ribbon sign typical of sporadic CJD (Figure 2).