case_images: PMC10961069_01
case_images: Before treatment, approximately 2.5cm x 1.5 cm white patches on the patient's forehead.
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case_images: Dermatological examination revealed a white patch on the forehead measuring approximately 2.5cmx1.5 cm with clear borders (Figure 1).
case_images: Before treatment, reflectance confocal microscopy (RCM) revealed complete depigmentation of the basal layer of the epidermis.
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case_images: PMC10961069_01_CCID-17-707-g0002.jpg
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case_images: Reflectance confocal microscopy (RCM) revealed complete depigmentation of the basal layer of the epidermis (Figure 2).
case_images: After 30 days after treatment, the white macular rash was completely re-pigmented.
case_images: CCID-17-707-g0003.jpg
case_images: PMC10961069_01_CCID-17-707-g0003.jpg
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case_images: After obtaining the patient's written informed consent, the patient was given 10 mg/d oral tofacitinib, without the combination of phototherapy and topical medication. After 30 days, the white macular rash was completely re-pigmented (Figure 3), the pigment granules in the basal layer of the epidermis returned to normal on RCM (Figure 4), and no significant abnormalities were found on imaging and laboratory examination, including frontal and lateral chest radiographs, complete blood count, liver function tests, kidney function tests, plasma lipid levels, D-dimer, hepatitis B, and PPD test.
case_images: After 30 days after treatment, the pigment granules in the basal layer of the epidermis returned to normal on RCM.
case_images: CCID-17-707-g0004.jpg
case_images: PMC10961069_01_CCID-17-707-g0004.jpg
case_images: f0004
case_images: After obtaining the patient's written informed consent, the patient was given 10 mg/d oral tofacitinib, without the combination of phototherapy and topical medication. After 30 days, the white macular rash was completely re-pigmented (Figure 3), the pigment granules in the basal layer of the epidermis returned to normal on RCM (Figure 4), and no significant abnormalities were found on imaging and laboratory examination, including frontal and lateral chest radiographs, complete blood count, liver function tests, kidney function tests, plasma lipid levels, D-dimer, hepatitis B, and PPD test.