case_images: PMC11813744_01
case_images: Pathological findings of breast malignancy and colon malignancy. breast malignancy: HE staining (A); ER+ (C); PR+ (E); HER2+ (G); Ki67 15%+ (I); E-Cadherin+ (K); colon malignancy: HE staining (B); ER- (D); PR- (F); HER2- (H); Ki67 50%+ (J); E-Cadherin+ (L). HE staining: Hematoxylin-Eosin staining; ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor-2; Ki67: nuclear-associated antigen Ki67.
case_images: fonc-14-1391393-g001.jpg
case_images: PMC11813744_01_fonc-14-1391393-g001.jpg
case_images: f1
case_images: She had a previous diagnosis of ER- and PR-positive ( Figure 1 ), HER2 ++ (no further testing was done) invasive ductal carcinoma of the left breast 5 years before.
case_images: Colonoscopy revealed a mass of ascending colon.
case_images: fonc-14-1391393-g002.jpg
case_images: PMC11813744_01_fonc-14-1391393-g002.jpg
case_images: f2
case_images: During colonoscopy, a mass was found in the ascending colon ( Figure 2 ).
case_images: Immunohistochemical staining results of colonic malignancies. CK7+, CK20-, GATA3+. CK7: Cytokeratin 7; CK20: Cytokeratin 20; GATA3: GATA 3 binding protein.
case_images: fonc-14-1391393-g003.jpg
case_images: PMC11813744_01_fonc-14-1391393-g003.jpg
case_images: f3
case_images: Further immunohistochemical staining revealed positive results for Cytokeratin 7 (CK7), negative results for Cytokeratin 20 (CK20), and positive results for GATA 3 binding protein (GATA3) and E-Cadherin ( Figure 3 ).
case_images: Computedtomography (CT) scan, a solitary nodule was detected in the liver, indicating a metastatic lesion.
case_images: fonc-14-1391393-g004.jpg
case_images: PMC11813744_01_fonc-14-1391393-g004.jpg
case_images: f4
case_images: In a 14-month postoperative computed tomography (CT) scan, a solitary nodule was detected in the liver, indicating a metastatic lesion ( Figure 4 ).
case_images: Timeline depicting the treatment and follow-up of the patient.
case_images: fonc-14-1391393-g005.jpg
case_images: PMC11813744_01_fonc-14-1391393-g005.jpg
case_images: f5
case_images: Treatment and follow-up are organized into a timeline ( Figure 5 ).