case_images: PMC6477463_01
case_images: The right axillary skin appearance. Small reddish nodules were noted at the same site as the synchronous cutaneous metastasis.
case_images: crg-0013-0095-g01.jpg
case_images: PMC6477463_01_crg-0013-0095-g01.jpg
case_images: F1
case_images: After 6 years, the patient became aware of small, slowly growing reddish nodules on the scar of the primary surgery in his right axilla (Fig. 1).
case_images: Computed tomography imaging. Irregular thickening of the right axillary skin was noted.
case_images: crg-0013-0095-g02.jpg
case_images: PMC6477463_01_crg-0013-0095-g02.jpg
case_images: F2
case_images: Computed tomography revealed irregular thickening of the right axillary skin (Fig. 2), and no other signs of recurrence including lungs and the abdomen were observed.
case_images: Histopathological findings of the metachronous cutaneous metastasis of the right axillary skin. a Moderately to poorly differentiated adenocarcinoma with proliferation of atypical epithelium forming ductal and nest-like structure, showing similarity to the tissues of gastric cancer resected 6 years ago. HE. x100. b-d Immunohistochemical staining was positive for CK7 (c), and negative for CDX-2 (b) and CK20 (d).
case_images: crg-0013-0095-g03.jpg
case_images: PMC6477463_01_crg-0013-0095-g03.jpg
case_images: F3
case_images: Histopathological examination revealed moderately to poorly differentiated adenocarcinoma with proliferation of atypical epithelium forming ductal and nest-like structures, and immunohistochemistry showed CK7 positivity, CK20 negativity, CDX-2 negativity (Fig. 3).
case_images: Histopathological findings of the gastric cancer (a) and the synchronous cutaneous metastasis of the right axillary skin (b) resected 6 years ago. a, b Moderately to poorly differentiated adenocarcinoma was observed. Immunohistochemical staining was positive for CK7 and negative for CDX-2 and CK20 (not shown). HE. x100.
case_images: crg-0013-0095-g04.jpg
case_images: PMC6477463_01_crg-0013-0095-g04.jpg
case_images: F4
case_images: The histological appearance and the immunohistochemistry were identical to the tissues of the gastric carcinoma and the synchronous cutaneous metastasis resected 6 years ago (Fig. 4); therefore, a diagnosis of solitary late cutaneous metastasis from gastric cancer was made.