case_images: PMC7457521_01
case_images: 18F-DOPA PET/CT Pancreatic Imaging. 18F-DOPA PET/CT imaging in the case described demonstrates diffuse pancreatic uptake (a-c). A coronal maximal intensity projection (MIP) image with OSEM reconstruction is shown at 30-45 min after radionucleotide injection (a) with merged coronal (b) and axial (c) PET and CT images. The previous patient with the same KCNJ11 mutation demonstrated similar findings on 18F-DOPA PET-CT scanning with diffuse uptake throughout the pancreas at 44 min post-injection on both MIP and merged PET-CT coronal images (d, e)
case_images: 13633_2020_86_Fig1_HTML.jpg
case_images: PMC7457521_02_13633_2020_86_Fig1_HTML.jpg
case_images: Fig1
case_images: Similar scan findings to our case were noted (Fig. 1D-E).
case_images: PMC7457521_02
case_images: 18F-DOPA PET/CT Pancreatic Imaging. 18F-DOPA PET/CT imaging in the case described demonstrates diffuse pancreatic uptake (a-c). A coronal maximal intensity projection (MIP) image with OSEM reconstruction is shown at 30-45 min after radionucleotide injection (a) with merged coronal (b) and axial (c) PET and CT images. The previous patient with the same KCNJ11 mutation demonstrated similar findings on 18F-DOPA PET-CT scanning with diffuse uptake throughout the pancreas at 44 min post-injection on both MIP and merged PET-CT coronal images (d, e)
case_images: 13633_2020_86_Fig1_HTML.jpg
case_images: PMC7457521_02_13633_2020_86_Fig1_HTML.jpg
case_images: Fig1
case_images: Similar scan findings to our case were noted (Fig. 1D-E).
case_images: PMC7457521_03
case_images: Focal CHI Lesion Histology. (a) Haematoxylin & eosin and (b) insulin staining of the resected pancreas revealed a 4.9 x 1.7 mm nodular lesion consistent with the presence of a focal lesion. Size marker is equivalent to 0.5 mm
case_images: 13633_2020_86_Fig2_HTML.jpg
case_images: PMC7457521_03_13633_2020_86_Fig2_HTML.jpg
case_images: Fig2
case_images: The histology demonstrated islands of endocrine cells, predominantly insulin and proinsulin positive, interspersed by bands of fibrous tissue and some acinar cells, consistent with a focal lesion (Fig. 2).