case_images: PMC6745162_01
case_images: Large fungating mass centered in the duodenum.
case_images: CRIPA2019-1713546.001.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.001.jpg
case_images: fig1
case_images: The mass was centered in the lumen of the duodenum with a well-demarcated (pushing) front of macroscopic invasion into the pancreas (Figure 1).
case_images: (a and b) Duodenal tumor adjacent to pancreatic heterotopia composed of pancreatic acini, islets of Langerhans, and ducts (original magnification x100 and x200).
case_images: CRIPA2019-1713546.002.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.002.jpg
case_images: fig2
case_images: The neoplasm was located in the duodenum adjacent to an area of pancreatic heterotopia (Figures 2(a) and 2(b)).
case_images: (a and b) Neuroendocrine cell component (original magnification x100 and x400).
case_images: CRIPA2019-1713546.003.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.003.jpg
case_images: fig3
case_images: Some other areas demonstrated pseudorosettes (Figures 3(a) and 3(b)), while others showed a typical acinar pattern with cells that had moderate to abundant granular eosinophilic cytoplasm, nuclei with open chromatin and prominent nucleoli, and increased mitotic figures (40/10 hpf) (Figures 4(a) and 4(b)).
case_images: (a and b) Acinar cell component (original magnification x100 and x400).
case_images: CRIPA2019-1713546.004.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.004.jpg
case_images: fig4
case_images: Some other areas demonstrated pseudorosettes (Figures 3(a) and 3(b)), while others showed a typical acinar pattern with cells that had moderate to abundant granular eosinophilic cytoplasm, nuclei with open chromatin and prominent nucleoli, and increased mitotic figures (40/10 hpf) (Figures 4(a) and 4(b)).
case_images: (a and b) Trypsin positivity in the acinar component (original magnification x100 and x200).
case_images: CRIPA2019-1713546.005.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.005.jpg
case_images: fig5
case_images: (a and b) Synaptophysin in the neuroendocrine component (original magnification x100 and x200).
case_images: CRIPA2019-1713546.006.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.006.jpg
case_images: fig6
case_images: BCL-10, as well as a neuroendocrine population that stained positively for synaptophysin (Figures 6(a) and 6(b)) and chromogranin (Figures 7(a) and 7(b)). Both acinar and neuroendocrine cell populations made up >25%-30% of the lesion, thus the patient was diagnosed with a MAEC.
case_images: (a and b) Chromogranin in the neuroendocrine component (original magnification x100 and x200).
case_images: CRIPA2019-1713546.007.jpg
case_images: PMC6745162_01_CRIPA2019-1713546.007.jpg
case_images: fig7
case_images: BCL-10, as well as a neuroendocrine population that stained positively for synaptophysin (Figures 6(a) and 6(b)) and chromogranin (Figures 7(a) and 7(b)). Both acinar and neuroendocrine cell populations made up >25%-30% of the lesion, thus the patient was diagnosed with a MAEC.