case_images: PMC10711076_01
case_images: Ultrasound examination of the contents of the patient's scrotum (in this case, the right testicle) performed prior to the final indication for surgery. According to the final evaluation, it was determined that it is a malignant tumour developing from testicular tissue that also extends into the epididymis, causing induration in this location. As previously noted in the text, the dilation of the veins of the pampiniformis plexus of the first degree on the left was a secondary finding. No additional pathologies were discovered. This was the decisive examination on the basis of which the patient was indicated for orchiectomy.
case_images: fimmu-14-1253120-g002.jpg
case_images: PMC10711076_01_fimmu-14-1253120-g002.jpg
case_images: f2
case_images: Based on the results of the subsequent ultrasound examination, a diagnosis of a tumour arising from the testicular tissue with simultaneous induration (suspicious malignant infiltration) of the epididymis on the right was made ( Figure 2 ).
case_images: The testicle, epididymis, and spermatic cord complex (A) were sent to the Pathology department of the Ostrava University Hospital following a radical orchiectomy. The testes and spermatic cord showed no obvious macroscopical pathology. The testis sheaths were slightly thickened. However, a solid lesion approx. 1 x 2 x 2 cm in size primarily whitish in colour was present in the epididymis (black arrows on the left, the lesion can be seen on both sides of the cut). (B-E) demonstrate the typical microscopic structures seen in sarcoidosis when stained with haematoxylin and eosin, particularly confluent non-caseating epithelioid granulomas. Another common trait is the presence of numerous asteroid bodies (white arrows with black outlines). Rich lymphocytic infiltration can also be seen around the granulomas. (E) shows the immunohistochemical staining for CD68 (histiocytic marker), which was highly positive in our case, as is typical of this type of cells.
case_images: fimmu-14-1253120-g003.jpg
case_images: PMC10711076_01_fimmu-14-1253120-g003.jpg
case_images: f3
case_images: There were no other significant macroscopic findings ( Figure 3 ). CD68 diffusely using immunohistochemical techniques. CKAE1/AE3 expression, on the other hand, was not observed ( Figure 3 ).