case_images: PMC9286925_01
case_images: Liver portal triad is expanded by lymphocytes, eosinophils, and noncaseating granulomatous inflammation. H&E stain of liver tissue. No interface hepatitis or proliferating bile ductules. Original magnification, 400x.
case_images: CRIID2022-7949471.001.jpg
case_images: PMC9286925_01_CRIID2022-7949471.001.jpg
case_images: fig1
case_images: This showed portal triad inflammation involving lymphocytes, eosinophils, and granulomatous inflammation (Figure 1), as well as rare lobular microgranulomata (Figure 2).
case_images: Lobular microgranuloma in the liver. H&E stain of liver tissue. Original magnification, 400x.
case_images: CRIID2022-7949471.002.jpg
case_images: PMC9286925_01_CRIID2022-7949471.002.jpg
case_images: fig2
case_images: This showed portal triad inflammation involving lymphocytes, eosinophils, and granulomatous inflammation (Figure 1), as well as rare lobular microgranulomata (Figure 2).
case_images: Immunohistochemical staining of CD68-positive macrophages/Kupffer cells (brown stain) in the liver. An excessive number of macrophages are located in sinusoids.
case_images: CRIID2022-7949471.003.jpg
case_images: PMC9286925_01_CRIID2022-7949471.003.jpg
case_images: fig3
case_images: Liver sinusoids had excessive numbers of Kupffer cells (Figure 3) and T-lymphocytes (Figure 4).
case_images: Immunohistochemical staining of CD3-positive T-lymphocytes (brown stain) in the liver. An excessive number of T-lymphocytes are in sinusoids.
case_images: CRIID2022-7949471.004.jpg
case_images: PMC9286925_01_CRIID2022-7949471.004.jpg
case_images: fig4
case_images: Liver sinusoids had excessive numbers of Kupffer cells (Figure 3) and T-lymphocytes (Figure 4).
case_images: Sinusoidal histiocytic hemophagocytosis. H&E stain of liver tissue. Examples of mature red cells within histiocyte cytoplasm as well as probable degenerate neutrophils within histiocytes are circled. Original magnification, 400x.
case_images: CRIID2022-7949471.005.jpg
case_images: PMC9286925_01_CRIID2022-7949471.005.jpg
case_images: fig5
case_images: Occasional benign appearing histiocytes/Kupffer cells had findings of hemophagocytosis of red blood cells and probable leukocytes (Figure 5).