case_images: PMC3271982_01
case_images: Mammography of the left breast, showing a 1.1 x 2.2-cm, well-demarcated, oval, isodense mass that was partly indistinct (arrow).
case_images: 1477-7819-10-12-1.jpg
case_images: PMC3271982_01_1477-7819-10-12-1.jpg
case_images: F1
case_images: Mammography showed a 22-mm, well-demarcated, oval, isodense mass that was partly indistinct (BI-RADS category 4) (Figure 1), and ultrasonography revealed a 20 x 15 x 8.8-mm, well-demarcated, hypoechoic lesion with slightly irregular margins in the outer part of the left breast (Figure 2).
case_images: Ultrasonography of the breast shows a 20 x 15 x 8.8-mm, well-demarcated, low-echoic lesion with slightly irregular margins (arrow).
case_images: 1477-7819-10-12-2.jpg
case_images: PMC3271982_01_1477-7819-10-12-2.jpg
case_images: F2
case_images: Mammography showed a 22-mm, well-demarcated, oval, isodense mass that was partly indistinct (BI-RADS category 4) (Figure 1), and ultrasonography revealed a 20 x 15 x 8.8-mm, well-demarcated, hypoechoic lesion with slightly irregular margins in the outer part of the left breast (Figure 2).
case_images: a) MRI of the left breast, showing a well-circumscribed mass with a high signal intensity on T2WI. b) On contrast-enhanced T1WI, the left breast lesion appeared as an enhanced mass with a microlobulated margin. c-f) The lesion on dynamic contrast MRI shows a peak in signal intensity within 90 seconds, after contrast injection.
case_images: 1477-7819-10-12-3.jpg
case_images: PMC3271982_01_1477-7819-10-12-3.jpg
case_images: F3
case_images: MRI displayed a well-circumscribed mass with high signal intensity on T2-weighted images (T2WI) (Figure 3a). On contrast-enhanced T1-weighted images (T1WI), the mass showed strong enhancement with a microlobulated margin (Figure 3b). The signal intensity peaked within 90 seconds after the intravenous injection of the contrast medium gadolinium (Figure 3c-f).
case_images: Gross pathologic appearance of the myoid hamartoma. The cut surface of the lesion shows a yellow-white, well-circumscribed, non-encapsulated mass, resembling a fibroadenoma.
case_images: 1477-7819-10-12-4.jpg
case_images: PMC3271982_01_1477-7819-10-12-4.jpg
case_images: F4
case_images: Macroscopically, the mass was completely excised and the cut surface of the lesion showed a yellow-white, well-circumscribed, non-encapsulated mass, resembling a fibroadenoma (Figure 4).
case_images: Hematoxylin and eosin and immunohistochemical staining of the breast tumor specimen. a) Hematoxylin and eosin staining of the breast tumor specimen shows a delicately encapsulated mass comprising fibrous and adipose tissue (Original magnification x 50). b-d) Immunohistochemical staining for smooth muscle actin, desmin, and HHF35 shows the smooth muscle histogenesis of stromal spindle cells (Original magnification x 150).
case_images: 1477-7819-10-12-5.jpg
case_images: PMC3271982_01_1477-7819-10-12-5.jpg
case_images: F5
case_images: Microscopically, Hematoxylin and eosin staining showed benign ductal and lobular units, adipose tissue, fibrous stroma and bundles of elongated spindle cells in a disorganized pattern (Figure 5a). Immunohistochemically, the smooth muscle tissue stained diffusely positive for smooth-muscle actin (SMA), vimentin, desmin, and HHF35 (Figure 5b-d).