case_images: PMC5958585_01
case_images: Crops of small, red-yellow dome-shaped papules of approx. 6 mm with well-defined borders located on the anterior medial thigh
case_images: JFMPC-7-267-g001.jpg
case_images: PMC5958585_01_JFMPC-7-267-g001.jpg
case_images: F1
case_images: Physical examination revealed multiple, nodular/firm pearly-yellow papules distributed bilaterally on the skin of the anterior thighs and on the right elbow [Figure 1].
case_images: Appearance of venous blood following phlebotomy, exhibiting a thick, milky supernatant
case_images: JFMPC-7-267-g002.jpg
case_images: PMC5958585_01_JFMPC-7-267-g002.jpg
case_images: F2
case_images: During routine phlebotomy, the patient's blood appeared lipemic with a thick, milky supernatant [Figure 2].
case_images: Biopsy photo showing changes of lichen simplex chronicus above collections of lipid-laden histiocytes and areas of extracellular lipid deposition, including cholesterol clefts. (H and E, x20)
case_images: JFMPC-7-267-g003.jpg
case_images: PMC5958585_01_JFMPC-7-267-g003.jpg
case_images: F3
case_images: A shave biopsy of the skin lesions revealed the collections of lipid-laden histiocytes and areas of extracellular lipid deposition, including cholesterol clefts, consistent with a diagnosis of eruptive xanthomatosis [Figures 3 and 4]. Additional stains and cultures for infectious organisms were all negative.
case_images: Within the dermis, there are somewhat nodular collections of lipid-laden histiocytes highlighted by a CD68 stain. Areas of extracellular lipid deposition are also seen including cholesterol clefts. (H and E, x100)
case_images: JFMPC-7-267-g004.jpg
case_images: PMC5958585_01_JFMPC-7-267-g004.jpg
case_images: F4
case_images: A shave biopsy of the skin lesions revealed the collections of lipid-laden histiocytes and areas of extracellular lipid deposition, including cholesterol clefts, consistent with a diagnosis of eruptive xanthomatosis [Figures 3 and 4]. Additional stains and cultures for infectious organisms were all negative.