case_images: PMC5306993_01
case_images: Transurethral bladder resection specimen displaying plasmacytoid tumor cells, with eccentric nuclei and eosinophilic cytoplasm. There is occasional intracytoplasmic vacuolization (H&E, x400).
case_images: CRIPA2017-5209059.001.jpg
case_images: PMC5306993_01_CRIPA2017-5209059.001.jpg
case_images: fig1
case_images: On H&E staining, the basic morphology of the tumor cells was plasmacytoid, with eccentric nuclei and eosinophilic cytoplasm (Figure 1).
case_images: Strong and diffuse nuclear immunoreactivity for GATA3 by tumor cells in the transurethral bladder resection specimen (x400).
case_images: CRIPA2017-5209059.002.jpg
case_images: PMC5306993_01_CRIPA2017-5209059.002.jpg
case_images: fig2
case_images: Tumor cells displayed both strong and diffuse nuclear reactivity for p53 and GATA3 (Figure 2).
case_images: Duodenal biopsy with atypical cells in submucosal location, showing enlarged nuclei and nucleoli, with partial plasmacytoid morphology. These cells were presented in a single cell pattern (H&E, x400).
case_images: CRIPA2017-5209059.003.jpg
case_images: PMC5306993_01_CRIPA2017-5209059.003.jpg
case_images: fig3
case_images: Some sparse interspersed atypical cells were noted in this layer, showing enlarged nuclei and nucleoli, with partial plasmacytoid morphology (Figure 3).
case_images: Duodenal biopsy showing strong nuclear GATA3 immunoreactivity in many tumor cells, which are observed more readily on immunostaining than on H&E histology (x100).
case_images: CRIPA2017-5209059.004.jpg
case_images: PMC5306993_01_CRIPA2017-5209059.004.jpg
case_images: fig4
case_images: They were immunoreactive for OSCAR pankeratin and GATA3 and, thus, were considered consistent with the previously diagnosed PUC (Figure 4).