case_images: PMC10265369_01
case_images: Intestinal and extraintestinal clinical manifestation of the patient at presentation: (A) alopecia, hyperpigmentation of skin on the palms and scalp, and onychodystrophy in all digits most notably in thumbs. Multiple polyps accompanying mucosal edema and hyperemia were observed in the (B) stomach and (C) colon.
case_images: 10.1177_23247096231179451-fig1.jpg
case_images: PMC10265369_01_10.1177_23247096231179451-fig1.jpg
case_images: fig1-23247096231179451
case_images: He also noticed generalized muscle loss, bilateral leg edema, progressive alopecia, onychodystrophy in all digits, and skin discoloration most notably on the palms, soles, and scalp (Figure 1A). Esophagogastroduodenoscopy and colonoscopy revealed multiple hyperemic polyps in the stomach, duodenum, terminal ileum, and colon (Figure 1B and C).
case_images: Follow-up endoscopic evaluation after treating with infliximab: Significant regression in both polyps' size and number in the (A) stomach and (B) entire colon.
case_images: 10.1177_23247096231179451-fig2.jpg
case_images: PMC10265369_01_10.1177_23247096231179451-fig2.jpg
case_images: fig2-23247096231179451
case_images: Endoscopic evaluation 24 months after the initiation of infliximab showed significant regression of polyposis in the stomach and colon (Figure 2).