case_images: PMC11192191_01
case_images: MRI (Plain) of the Brain. (A-C) are T1-weighted; (D-F) are T2-weighted; (G-I) are FLAIR-weighted. (A-C) show hypointense regions and (D-I) show hyperintense regions in the periventricular white matter with multiple cystic spaces. The splenium of corpus callosum is also involved. Blue arrows mark the abnormal regions.
case_images: DNND-14-75-g0001.jpg
case_images: PMC11192191_01_DNND-14-75-g0001.jpg
case_images: f0001
case_images: The corresponding fundoscopic image is available in the Supplementary Figure 1. These findings also extended to involve the splenium of the corpus callosum, suggesting white matter demyelination with encephalomalacia (Figure 1).
case_images: MRI (Plain) of the Brain. (A-C) are FLAIR-weighted, T2-weighted, and T1-weighted MRI respectively. (A and B) show hyperintensity in the bilateral dentate nucleus, whereas (C) shows hypointensity in the bilateral dentate nucleus (marked by white arrows).
case_images: DNND-14-75-g0002.jpg
case_images: PMC11192191_01_DNND-14-75-g0002.jpg
case_images: f0002
case_images: Mild to minimal white matter demyelination changes were also detected in the frontal region (Figure 2).
case_images: Postcontrast study with gadolinium-enhanced MRI of the brain; (A-C) show mild focal linear enhancement on both sides with greater enhancement on the right side (marked by white arrows).
case_images: DNND-14-75-g0003.jpg
case_images: PMC11192191_01_DNND-14-75-g0003.jpg
case_images: f0003
case_images: Subsequent post-contrast MRI with gadolinium enhancement revealed mild focal linear enhancement on both sides (Figure 3).