case_images: PMC10753133_01
case_images: PMC10753133_02
case_images: PMC10753133_03
case_images: Serum VPA levels (mg/L) during hospital. HP, hemoperfusion; CRRT, continuous renal replacement therapy. The serum drug concentration in acute valproic acid (VPA) poisoning is well above the normal range. In case 1, the initial concentration reached 635.77 mg/L. HP and CRRT measures will rapidly reduce the serum drug concentration of VPA. As the drug concentration in the tissues and organs is still high, the drug redistribution leads to an increase in the blood drug concentration. It should be considered that HP and CRRT measures should be repeated or repeated to ensure rapid elimination of the drug.
case_images: CCR3-12-e8367-g001.jpg
case_images: PMC10753133_03_CCR3-12-e8367-g001.jpg
case_images: ccr38367-fig-0001