case_images: PMC10436618_01
case_images: Bone marrow biopsy showing hemophagocytosis by histiocyte.
case_images: fimmu-14-1223062-g001.jpg
case_images: PMC10436618_01_fimmu-14-1223062-g001.jpg
case_images: f1
case_images: Bone marrow biopsy revealed occasional hemophagocytic cells ( Figure 1 ).
case_images: The patient's clinical course in hospital. DXM, dexamethasone; MP, Methylprednisolone; PSL, prednisolone;VP-16,etoposide;CsA, Cyclosporine A;CTX, cyclophosphamide.
case_images: fimmu-14-1223062-g002.jpg
case_images: PMC10436618_01_fimmu-14-1223062-g002.jpg
case_images: f2
case_images: SLE complicated with secondary HLH, and 5 days of pulsed intravenous methylprednisolone with a dose of 200mg daily was administered for shock treatment. Subsequently, a combination treatment of etoposide (100mgx3/week, accumulated 1000mg), cyclosporine (50mg, bid), cyclophosphamide (200mg, qw), and entecavir was administered, which successfully reversed the patient's body temperature to the normal range ( Figure 2 ).