case_images: PMC11064694_01
case_images: LCA patient's ultrasound and CT images. (A,B) Ultrasound indicated multiple solid slightly hyperechoic masses were diffusely distributed in the spleen, measuring approximately 26 mm x 23 mm, 12 mm x 13 mm, 19 mm x 19 mm, 9 mm x 9 mm, 8 mm x 5 mm, etc. (C) CT revealed multiple nodular lesions in the spleen. (D) Enhancement reveals multiple masses of varying sizes within the spleen, with uneven internal enhancement and weaker than the spleen. The arrows point to the tumor.
case_images: fped-12-1383015-g001.jpg
case_images: PMC11064694_01_fped-12-1383015-g001.jpg
case_images: F1
case_images: Some lesions exhibited obvious enhancement with indistinct edges and were surrounded by splenic vascular branches (Figure 1).
case_images: Postoperative pathological examinations. (A) The spleen significantly enlarged, with measured 10.5 cm x 5 cm x 3 cm. (B) The spleen is grayish-red, with nodular cut surfaces, solid, and slightly firm in consistency. (C) Hematoxylin and eosin staining of LCA. The tumor consists of an interlacing vascular network similar to splenic sinus, with papillary projections and cystic cavities (IHC x 5). (D) Papillary structures are seen in the lumen of the blood vessels (IHC x 10). (E) Nuclei with no obvious heterogeneity. (IHC x 20). (F) ERG staining: ERG(+) (IHC x 20).
case_images: fped-12-1383015-g002.jpg
case_images: PMC11064694_01_fped-12-1383015-g002.jpg
case_images: F2
case_images: Tumor cells are homogeneous, and nuclear division is rare (Figure 2).