case_images: PMC10634416_01
case_images: CT and ultrasound features of retroperitoneal anastomosing hemangioma. (A) Plain scan. (B) Arterial phase. (C) Venous phase. (D, E) The lesion exhibits a hypoechoic mass with slight blood flow signals in the inferior anteromedial region of the right kidney. (F) Contrast-enhanced ultrasound demonstrates homogeneous and "slow-in and slow-out" low enhancement.
case_images: fonc-13-1269631-g001.jpg
case_images: PMC10634416_01_fonc-13-1269631-g001.jpg
case_images: f1
case_images: Notably, the arterial phase demonstrated significant enhancement of the mass, which extended to the center during the venous phase ( Figures 1A-C ). The mass displayed a clear boundary and a homogeneous echo signal, and exhibited gradual enhancement during "slow-in and slow-out" phases ( Figures 1D-F ).
case_images: MRI and pathological features of retroperitoneal anastomosing hemangioma. (A) T2-weighted image. (B) T1-weighted image. (C) Diffusion-weighted image. (D) Arterial phase post-contrast T1-weighted image. (E) Venous phase post-contrast T1-weighted image. (F) Hematoxylin and eosin (HE) staining (200x). (G, H) Immunohistochemistry (200x) showed vascular endothelial cell markers CD31 (G) and CD34 (H) were positive.
case_images: fonc-13-1269631-g002.jpg
case_images: PMC10634416_01_fonc-13-1269631-g002.jpg
case_images: f2
case_images: T1-weighted imaging (T1WI) and a high signal on T2-weighted imaging (T2WI), with a clear boundary and a slightly increased signal on the diffusion-weighted image (DWI) ( Figures 2A-C ). The enhancement of the mass showed progressive centripetal filling ( Figures 2D, E ). Pathological examination revealed a well-defined mass with nodular growth, composed of interconnected and anastomosing blood vessels ( Figure 2F ). Immunohistochemical analysis demonstrated positive staining for CD31 ( Figure 2G ), CD34 ( Figure 2H ), SMA, and focal Ki-67, while Calponin, S-100, Des CK, D2-40, CK5/6, HMB45, Melan-A, NSE, and Melan-A showed negative results.