case_images: PMC8316747_01
case_images: Biopsy of the primary nasopharyngeal neoplasm (A-C), right upper arm lesion (D), and lung metastases lesion (E). (A) Epithelial papillary hyperplasia (hematoxylin and eosin, original magnification x10). (B) Squamous differentiation (hematoxylin and eosin, original magnification x20). (C) Base-like arrangement (hematoxylin and eosin, original magnification x20). (D) Representative images of the metastatic carcinoma in the right upper arm (hematoxylin and eosin, original magnification x20). (E) Representative images of the metastatic carcinoma in the lung (hematoxylin and eosin, original magnification x20).
case_images: fonc-11-665652-g001.jpg
case_images: PMC8316747_01_fonc-11-665652-g001.jpg
case_images: f1
case_images: Nasal endoscopy was performed, and a biopsy of the nasopharyngeal neoplasm confirmed basaloid squamous cell carcinoma ( Figures 1A-C ). We performed a biopsy of the right upper arm lesion ( Figure 1D ). Meanwhile, to exclude primary lung malignancy, a biopsy of a lung lesion was performed, which showed that the pathology was consistent with results of the right upper arm and nasopharynx biopsy ( Figure 1E ); the metastatic lung lesions revealed progressive disease.
case_images: MRI of the dural and multiple brain metastases. (A) T1-weighted axial image shows cerebellum lesions. (B) T1-weighted sagittal image shows lesions in the cerebellum, occipital lobe, parietal lobe, and frontal lobe. (C) T1-weighted coronal image shows dural metastasis and lesions in the parietal and temporal lobes.
case_images: fonc-11-665652-g002.jpg
case_images: PMC8316747_01_fonc-11-665652-g002.jpg
case_images: f2
case_images: MRI was then performed and revealed dural metastasis and multiple intracranial metastatic lesions throughout both cerebral hemispheres and the cerebellum, including the frontal lobe, parietal lobe, and occipital lobe ( Figure 2 ).