case_images: PMC10754631_01
case_images: CMV titer and corresponding antiviral medication received throughout the course of the disease. VCG: valganciclovir. GCV: ganciclovir. IL-2: interleukin-2 (aldesleukin). CMV titer: copies/ml.
case_images: CRIGM2023-8888429.001.jpg
case_images: PMC10754631_01_CRIGM2023-8888429.001.jpg
case_images: fig1
case_images: Her CMV titers remained elevated (Figure 1). After exhausting all medical treatment options and due to the worsening of CMV colitis, a multidisciplinary decision was made to proceed with a pan colectomy, which was performed around mid-2021, as indicated by an arrow on Figure 1. Initial postoperative CMV titers remained elevated (Figure 1), but subsequent measurements ranged between 1000 and 2000 copies/ml, resulting in significant clinical improvement.
case_images: Endoscopic image showing colonic ulceration.
case_images: CRIGM2023-8888429.002.jpg
case_images: PMC10754631_01_CRIGM2023-8888429.002.jpg
case_images: fig2
case_images: A repeat colonoscopy (Figure 2) revealed pan colitis with ulceration, and the biopsy confirmed severe colitis with positive CMV inclusion bodies and immunohistochemistry from multiple sites of ulceration and inflammation (Figures 3(a) and 3(b)).
case_images: Inclusion bodies on colonic biopsy with positive immunohistochemistry for CMV.
case_images: CRIGM2023-8888429.003.jpg
case_images: PMC10754631_01_CRIGM2023-8888429.003.jpg
case_images: fig3
case_images: A repeat colonoscopy (Figure 2) revealed pan colitis with ulceration, and the biopsy confirmed severe colitis with positive CMV inclusion bodies and immunohistochemistry from multiple sites of ulceration and inflammation (Figures 3(a) and 3(b)).