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case_images: The chest CT revealed the absence of a thymus.
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case_images: Table 2 ). The chest computed tomography (CT) revealed the absence of a thymus and showed a hazy opacity ( Figure 1 ). To sum up, the infant developed severe BCGosis and progressed rapidly, even developing complicated HPS.
case_images: The treatment timeline of the patient.
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case_images: We have summarized the timeline of patient treatment and disease progression in  Figure 2 .
case_images: Diagnosis of MTB infection using mNGS. (A) The reads mapped to the MTB genome with coverage of 14.8487% in the blood. The distribution of species-specific reads aligns with the MTB in the blood. (B) The reads mapped to the MTB genome with coverage of 29.1761% in the CSF. The distribution of species-specific reads aligns with the MTB in the CSF.
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case_images: The reads mapped to the MTB genome with coverage of 14.8487% in the blood ( Figure 3A ) and 29.1761% in the CSF ( Figure 3B ).
case_images: Genetic detection of the variant in the IL2RG gene (Exon 3: c.391C>T; p.Gln131Ter) among the patient, his father (wild-type) and his mother (carrier).
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case_images: Through the above WES and Sanger Sequencing process, we accurately identified the mutation in the IL2RG gene (Exon 3: c.391C>T; p.Gln131Ter) in the patient ( Figure 4 ). The genetic detection of the father was wild-type, and the genetic detection of the mother was with respect to the mutation in the IL2RG gene (Exon 3: c.391C>T; p.Gln131Ter.  Figure 4 ).