case_images: PMC7403923_01
case_images: Tense bullae over erythematous plaques on the trunk (a) and left upper extremity (b).
case_images: CRIRH2020-8873337.001.jpg
case_images: PMC7403923_01_CRIRH2020-8873337.001.jpg
case_images: fig1
case_images: Physical examination was notable for fever (temp 102.8 F/39.3 C) and clear fluid-filled bullae over the face, trunk, and extremities with crusting lesions on the lips, soft palate, and genitals (Figure 1).
case_images: Direct immunofluorescence with linear deposition of IgG and IgA at the basement membrane zone (a) and salt-split preparation with immune complex deposition at the dermal site (b).
case_images: CRIRH2020-8873337.002.jpg
case_images: PMC7403923_01_CRIRH2020-8873337.002.jpg
case_images: fig2
case_images: Direct immunofluorescence (IF) showed linear deposition of IgG and IgA at the dermal side with salt-split skin preparation consistent with BSLE (Figure 2).
case_images: Worsening blistering eruption on the abdomen.
case_images: CRIRH2020-8873337.003.jpg
case_images: PMC7403923_01_CRIRH2020-8873337.003.jpg
case_images: fig3
case_images: Despite aggressive treatment, new blistering lesions continued to appear on the face (at the vermilion border of the lips and the nasal bridge), trunk, abdomen, and limbs (Figure 3).
case_images: Hypopigmented macules on the trunk (a) and upper extremity (b) with no bullae lesions after seven months of treatment with dapsone.
case_images: CRIRH2020-8873337.004.jpg
case_images: PMC7403923_01_CRIRH2020-8873337.004.jpg
case_images: fig4
case_images: The skin lesions showed a marked improvement with only few hypopigmented macules on the trunk and upper extremities (Figure 4).