case_images: PMC3572682_01
case_images: CT scan of abdomen and pelvis with contrast in (a) axial view and (b) coronal view showed well-defined 4.5 cm enhancing mass of mesocolon which was located anterior to descending duodenum, posterior to gastric antrum, and just medial to the hepatic flexure of colon.
case_images: CRIM.ONCMED2013-329472.001.jpg
case_images: PMC3572682_01_CRIM.ONCMED2013-329472.001.jpg
case_images: fig1
case_images: CT scan of abdomen and pelvis with contrast was performed to further evaluate the mass which showed well-defined 4.5 cm enhancing mass of mesocolon which was located anterior to descending duodenum, posterior to gastric antrum, and just medial to the hepatic flexure of colon (Figure 1).
case_images: (a) Clusters of cells surrounded by reticulin fibrosis known as Zellballen arrangement, typical of paraganglioma. (b) CD34 immunostain marking the numerous small capillaries in the tumor. (c) Chromogranin A immunohistochemical stain.
case_images: CRIM.ONCMED2013-329472.002.jpg
case_images: PMC3572682_01_CRIM.ONCMED2013-329472.002.jpg
case_images: fig2
case_images: This appearance is known as Zellballen arrangement, which is typical of paraganglioma (Figure 2(a)). The tumor was highly vascular in nature as highlighted by the CD34 immunostain (Figure 2(b)). AE1/AE3 cytokeratin and strongly immunoreactive for neuroendocrine markers CD56, chromogranin A (Figure 2(c)), and synaptophysin. Additional immunostains were performed to rule out carcinoid tumors and pheochromocytoma. 