case_images: PMC4710046_01
case_images: PMC4710046_02
case_images: The probandat 14 years of age. Note relative macrocephaly, coarse face, broad forehead, deep-set and widely spaced eyes, strabismus, broad nose bridge, shallow philtrum, thick lips. Hand X-ray showed delayed bone age.
case_images: 13039_2016_214_Fig1_HTML.jpg
case_images: PMC4710046_02_13039_2016_214_Fig1_HTML.jpg
case_images: Fig1
case_images: He had severe short stature and hands X-ray showed delayed bone age (Fig. 1).