case_images: PMC9891144_01
case_images: a In gastric mucosa, multiple black nodular lesions were identified with white light. The two largest lesions of 5 mm were present on the distal body. These lesions were suggestive of melanoma metastasis. b Similar black nodular lesion of 3 mm on the duodenum.
case_images: pjg-0030-0073-g01.jpg
case_images: PMC9891144_01_pjg-0030-0073-g01.jpg
case_images: F1
case_images: Upper endoscopy was performed showing multiple black nodular lesions in the stomach and duodenum (Fig. 1).
case_images: Narrow-band imaging: black patches present on the summit of elevated lesions. The lesions' base showed an enlarged regularly placed oval and elongated pit pattern in contrast to a small pit pattern of the surrounding normal gastric mucosa.
case_images: pjg-0030-0073-g02.jpg
case_images: PMC9891144_01_pjg-0030-0073-g02.jpg
case_images: F2
case_images: Narrow-band imaging revealed the presence of black patches on the top of these nodular lesions (Fig. 2).
case_images: a Lamina propria diffuse infiltration by epithelioid malignant neoplasia. Haematoxylin-eosin staining. x40. b Tumoural cells show intense and diffuse expression for HMB45. HMB45. x40.
case_images: pjg-0030-0073-g03.jpg
case_images: PMC9891144_01_pjg-0030-0073-g03.jpg
case_images: F3
case_images: Histopathological examination showed an epithelioid malignant injury with intense and diffuse HMB45 expression suggestive of pigmented melanoma (Fig. 3).