case_images: PMC10477776_01
case_images: Timeline of the patient's clinical course with major clinical events.
case_images: fonc-13-1216725-g001.jpg
case_images: PMC10477776_01_fonc-13-1216725-g001.jpg
case_images: f1
case_images: A timeline with relevant data is shown in  Figure 1 .
case_images: PMC10477776_02
case_images: Contrast-enhanced computed tomography scan of the pelvis showing lesions in trigone of bladder extending up to the left ureteral ostium.
case_images: fonc-13-1216725-g002.jpg
case_images: PMC10477776_02_fonc-13-1216725-g002.jpg
case_images: f2
case_images: CT scan ( Figure 2 ) and multiparametric magnetic resonance imaging (mpMRI) for bladder cancer showed a VI-RADS score of 5 and tumoral lesions in the trigone of the bladder extending up to the left ureteral ostium, with no lymphadenopathies detected. Clinicians performed transurethral resection of the bladder tumor (TURBT) as the treatment.
case_images: Enlarged lower third of the leg. Clinical appearance of multi-nodular lesion, biopsy showed cutaneous metastasis urothelial carcinoma. Microscopic view of biopsy specimen shows subcutaneous infiltration of urothelial cell carcinoma.
case_images: fonc-13-1216725-g003.jpg
case_images: PMC10477776_02_fonc-13-1216725-g003.jpg
case_images: f3
case_images: Two months after radical cystectomy, a multi-nodular lesion associated with skin rash in the lower third of the leg appeared ( Figure 3 ). A skin biopsy of the leg lesion was performed, showing poorly differentiated carcinomatous proliferation with extensive infiltration from atypical pleomorphic cells with round nuclei and a moderate amount of cytoplasm ( Figure 3 ).