case_images: PMC9989017_01
case_images: Pre-operative T2 (A) and post-gadolinum (B) sagittal and axial (C) MRI scans of our patient showing the extensive metastasis to hypothalamus. (D) post-gadolinium-enhanced T1-weighted sagittal spine MRI image showing leptomeningeal dissemination of medulloblastoma.
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case_images: PMC9989017_01_fped-11-1145941-g001.jpg
case_images: F1
case_images: Tomography (CT) scan showed a voluminous posterior fossa tumor with several supratentorial metastases, associated with ventricular dilatation. The gadolinium-enhanced MRI confirmed the presence of a cerebellar tumor with a voluminous metastasis in the hypothalamic site (Figure 1).
case_images: T2 (A) and FLAIR (B) axial MRI scans showing multifocal leukoencephalopathy after two months of maintenance treatment. Gadolinium-enhanced T1-weighted MRI (C, coronal section; D, axial section) shows a ring enhancement of the hypothalamic lesion compressing the chiasm and the optic tracts.
case_images: fped-11-1145941-g002.jpg
case_images: PMC9989017_01_fped-11-1145941-g002.jpg
case_images: F2
case_images: The MRI instead suggested radiological patterns of leukoencephalopathy (Figure 2).
case_images: Clinical course of the patient.
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case_images: PMC9989017_01_fped-11-1145941-g003.jpg
case_images: F3
case_images: The clinical course of the patient is depicted in Figure 3.