case_images: PMC10591023_01
case_images: Intraoral clinical picture of the lesion (a) on facial aspect; (b) on palatal aspect
case_images: FID-20-36-g001.jpg
case_images: PMC10591023_01_FID-20-36-g001.jpg
case_images: F1
case_images: Intraoral periapical radiograph showing the level of bone loss in the right maxillary quadrant from 5-8 region
case_images: FID-20-36-g002.jpg
case_images: PMC10591023_01_FID-20-36-g002.jpg
case_images: F2
case_images: Tooth number 7 was associated with severe bone loss and horizontal bone loss was seen around 6 (Figure 2).
case_images: Histopathological H&E image showing (a) fibrovascular connective tissue exhibiting proliferation of spindle-shaped cells; (b) hyper-cellular Antoni A pattern; (c) marked cellularity with fascicles of spindle cells, displaying short intersecting fascicles and whorls of Schwann cells;(d) spindle shaped cells with wavy nuclei along with cellular and nuclear pleomorphism
case_images: FID-20-36-g003.jpg
case_images: PMC10591023_01_FID-20-36-g003.jpg
case_images: F3
case_images: Cellular and nuclear pleomorphism was seen in focal areas (Figure 3).
case_images: Immunohistochemical images showing reactivity of cells for (a) S-100 protein, (b) Ki67, (c) Vimentin and (d) p53.
case_images: FID-20-36-g004.jpg
case_images: PMC10591023_01_FID-20-36-g004.jpg
case_images: F4
case_images: The tissue showed 100% positive immunohistochemical reactivity with S100 protein (Figure 4a), thus confirming the neural origin. Ki 67 (Figure 4b) showed 60% positivity in hot spot areas suggesting increased DNA proliferation and aggressive behavior of this tumor. Vimentin (Figure 4c) also showed positive reactivity in the connective tissue, while p53 (Figure 4d) was weakly positive, with only 10% of cells showing immunoreactivity. 
case_images: Intra-operative picture after excision of the lesion and extraction of 7 and 6
case_images: FID-20-36-g005.jpg
case_images: PMC10591023_01_FID-20-36-g005.jpg
case_images: F5
case_images: Extraction of 7 and 6 was performed due to anticipated poor prognosis. (Figure 5) Vulcanite bur was used to smoothen the sharp bony edges under irrigation.
case_images: Excised gingival mass
case_images: FID-20-36-g006.jpg
case_images: PMC10591023_01_FID-20-36-g006.jpg
case_images: F6