case_images: PMC11250236_01
case_images: Clinical course of case 1. History of antacid use. Endoscopic images of gastric fundic gland polyps before, during, and after taking esomeprazole (a PPI).
case_images: crg-2024-0018-0001-538833_F01.jpg
case_images: PMC11250236_01_crg-2024-0018-0001-538833_F01.jpg
case_images: F1
case_images: December 2012, the patient presented with anemia, accompanied by oozing from the erosions at the gastrointestinal anastomosis. During examination, multiple white FGPs, measuring 2-4 mm, were observed in the upper and lower parts of the gastric body (Fig. 1). Therefore, ranitidine was replaced with esomeprazole (20 mg/day), a PPI, which alleviated the patient's anemia (Fig. 1). However, the FGPs had increased in size to a maximum diameter of 20 mm (Fig. 1). Anastomotic erosion at the gastrointestinal anastomosis remained absent (Fig. 1).
case_images: PMC11250236_02
case_images: Clinical course of case 2. a History of antacid use. b Endoscopic imaging of gastric fundic gland polyps before, during, and after administration of vonoprazan (a P-CAB). c Endoscopic imaging of colon polyps before, during, and after vonoprazan administration.
case_images: crg-2024-0018-0001-538833_F02.jpg
case_images: PMC11250236_02_crg-2024-0018-0001-538833_F02.jpg
case_images: F2
case_images: FGPs and colon polyps were observed during surveillance EGD and colonoscopy, compared to those observed in the endoscopic findings in May 2021 (Fig. 2). Furthermore, the histopathological evaluation of biopsy specimens from the largest number of gastric polyps revealed cystic dilatation of the fundus gland. During this period, EGD and colonoscopy revealed a decrease in colon polyps and FGPs, with a maximum diameter of 4 mm (Fig. 2).