case_images: PMC4242059_01
case_images: Cranial MRI: T1 post-contrast image in axial view: Enhancing parenchymal nodule involving the left temporal lobe, the lenticular nucleus and the internal capsule
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case_images: F0001
case_images: A follow-up Magnetic resonance neuro-imaging studies (MRI), with and without contrast, identified a left temporal globular mass involving the lenticular nucleus and the internal capsule with edema and signal intensities suggestive of glial neoplasm (Figure 1, Figure 2).
case_images: Cranial MRI: T2 image in coronal view: Nodule with surrounding edema
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case_images: PMC4242059_01_PAMJ-18-236-g002.jpg
case_images: F0002
case_images: A follow-up Magnetic resonance neuro-imaging studies (MRI), with and without contrast, identified a left temporal globular mass involving the lenticular nucleus and the internal capsule with edema and signal intensities suggestive of glial neoplasm (Figure 1, Figure 2).
case_images: Granulomatous process involving neuroglial tissue (H&E x40)
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case_images: F0003
case_images: Pathological examination revealed neuroglial tissue heavily involved with multiple granulomas (Figure 3).
case_images: Nectrotising Granuloma with a central region of necrosis (H&E x 100)
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case_images: PMC4242059_01_PAMJ-18-236-g004.jpg
case_images: F0004
case_images: These lesions consisted of focal areas of fibrinoid necrosis, surrounded by a rim of mononuclear cells (Figure 4).
case_images: Granuloma with epithlioid cells and lymphocytes (H&E x200)
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case_images: F0005
case_images: Most cells also had a generous amount of pink cytoplasm (epithelioid cells) (Figure 5).
case_images: Masson trichrome staining highlighting Fibrosis surrouding granulomas (TM x 40)
case_images: PAMJ-18-236-g006.jpg
case_images: PMC4242059_01_PAMJ-18-236-g006.jpg
case_images: F0006
case_images: Trichrome staining (Figure 6). There was no definitive vasculitis, although some vessels had inflammatory cells around them.