case_images: PMC2972593_01
case_images: Magnetic resonance imaging showing rectal neoplasm (A) and perirectal nodes (B).
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case_images: PMC2972593_01_cln-65-10-1063-g001.jpg
case_images: f1-cln_65p1063
case_images: Melan-A expression were found. MRI revealed circumferential thickening due to rectal lesion with a 7.2 cm length and 1.8 cm thickness, leading to narrowing of the rectal lumen located 3.2 cm away from the anus and several enlarged perirectal nodes (Figure 1).
case_images: The rectum, the large nodes, and the tumor after an abdominalperineal resection.
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case_images: PMC2972593_01_cln-65-10-1063-g002.jpg
case_images: f2-cln_65p1063
case_images: An abdominoperineal resection was performed because a substantial part of the internal anal sphincter was invaded (Figure 2).
case_images: Anal melanoma. Cross-section of the external surface region (H&E x 100).
case_images: cln-65-10-1063-g003.jpg
case_images: PMC2972593_01_cln-65-10-1063-g003.jpg
case_images: f3-cln_65p1063
case_images: Histology (Figures 3, 4, 5) confirmed a malignant metastatic, epithelioid melanoma in 13 of the 14 examined lymph nodes.
case_images: Anal melanoma. Cross-section of the mucosa surface region (H&E x 100).
case_images: cln-65-10-1063-g004.jpg
case_images: PMC2972593_01_cln-65-10-1063-g004.jpg
case_images: f4-cln_65p1063
case_images: Histology (Figures 3, 4, 5) confirmed a malignant metastatic, epithelioid melanoma in 13 of the 14 examined lymph nodes.
case_images: Anal melanoma. Cross-section of the tumor region (H&E x 400).
case_images: cln-65-10-1063-g005.jpg
case_images: PMC2972593_01_cln-65-10-1063-g005.jpg
case_images: f5-cln_65p1063
case_images: Histology (Figures 3, 4, 5) confirmed a malignant metastatic, epithelioid melanoma in 13 of the 14 examined lymph nodes.