case_images: PMC6252184_01
case_images: (a) Computed tomography showed the right kidney tumor (arrow). (b) The right nephrectomy specimen contained a grayish tumor measuring 5.5cm x 5.0 cm on the upper pole (arrow). (c, d) Histologic sections of the resection specimen showed that the tumor formed a papillary structure, and the lumen was filled with eosinophilic substances considered colloids. Individual cancer cells had nuclear grooves, and findings suggestive of nuclear inclusions were also observed (arrow). (c): Original magnification x200, (d): Original magnification x400. (e, f) Immunohistochemistry revealed positive for thyroid transcription factor 1 (e) and thyroglobulin (f). Original magnification x400.
case_images: CRIE2018-7842792.001.jpg
case_images: PMC6252184_01_CRIE2018-7842792.001.jpg
case_images: fig1
case_images: In addition, CT revealed an irregular tumor mass projecting outward from the right kidney with no evidence of other metastatic lesions (Figure 1(a)). The pathology report revealed that the right nephrectomy specimen contained a grayish tumor measuring 5.5 x 5.0 cm on the upper pole (Figure 1(b)). Further, individual cancer cells had nuclear grooves, and findings suggestive of nuclear inclusions were observed (Figures 1(c) and 1(d)). Tg (Figures 1(e) and 1(f)). The patient was discharged from the hospital on postoperative day 7 without any complications.
case_images: PMC6252184_02
case_images: (a) Computed tomography showed the left kidney tumor (arrow). (b) The left nephrectomy specimen contained a light brown tumor measuring 4.5cm x 4.4 cm on the lower pole arrow. (c, d) Histologic sections of the resection specimen showed that the tumor formed a follicular structure, and was infiltrating and proliferating. (c): Original magnification x200, (d): Original magnification x400. (e, f) Immunohistochemistry revealed positive for thyroid transcription factor 1 (e) and thyroglobulin (f). Original magnification x400.
case_images: CRIE2018-7842792.002.jpg
case_images: PMC6252184_02_CRIE2018-7842792.002.jpg
case_images: fig2
case_images: TSH, 0.09 muIU/mL; F-T4, 1.35 ng/mL; Tg, 10500.0 ng/dL (Tg doubling time, 0.31 years); and TgAb, 11 IU/mL. CT revealed a left kidney tumor measuring 4.0 x 3.5 cm (Figure 2(a)). The Tg level was remarkably high; thus, recurrence of FTC was predominantly suspected. The pathology report revealed that the left nephrectomy specimen comprised a light brown tumor measuring 4.5 x 4.4 cm on the lower pole (Figure 2(b)). In addition, histological sections of the resected specimen revealed that the tumor formed a follicular structure and was undergoing infiltration and proliferation (Figures 2(c) and 2(d)). Tg (Figures 2(e) and 2(f)). The patient was discharged from the hospital on postoperative day 6 without any complications. The Tg level decreased postoperatively to 298 ng/dL.