case_images: PMC9643837_01
case_images: Images of 18F-FDG PET/CT. (A) No obvious abnormality is found in the maximum intensity projection (MIP) image. (B-D) The axial images of the abdominal cavity reveal slight FDG activity in the thickened gastric wall (long arrows; SUVmax 3.8). (E-G) Similarly, the axial images of the pelvic cavity show an abnormal mass with a slight FDG uptake in the right adnexal area (short arrows; SUVmax 3.0).
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case_images: PMC9643837_01_fonc-12-1013066-g001.jpg
case_images: f1
case_images: Fluorine 18 (18F) fluorodeoxyglucose (FDG) PET/CT ( Figure 1 ) results revealed slight FDG activity in the thickened gastric wall (SUVmax 3.8) and an abnormal mass in the right adnexal area (SUVmax 3.0).
case_images: Images of 68Ga-FAPI PET/CT. (A) The MIP image shows several lesions with varying degrees of FAPI uptake. (B-D) Axial views of abdominal cavity demonstrate significantly elevated FAPI activity in the thickened gastric wall (long arrows; SUVmax 9.8). (E-G) The axial images of pelvic cavity reveal abnormal FAPI uptake in the bilateral adnexal areas (short arrows; SUVmax of right 11.6, SUVmax of left 6.5). (C, D) Furthermore, 68Ga-FAPI PET/CT showed extensive peritoneal carcinomatosis with FAPI uptake (dotted arrows; SUVmax 3.9).
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case_images: PMC9643837_01_fonc-12-1013066-g002.jpg
case_images: f2
case_images: Figure 2 ) results demonstrated significantly elevated FAPI activity in the thickened gastric wall (SUVmax 9.8) and a mass in the right adnexal area (SUVmax 11.6). Furthermore, 68Ga-FAPI PET/CT showed extensive peritoneal carcinomatosis with FAPI uptake (SUVmax 3.9) and a mass in the left adnexal area with moderate FAPI activity (SUVmax 6.5).
case_images: Biopsy results of (A) gastric wall, (B) pelvic nodule, (C) right ovary, and (D) left ovary confirm that there are gastric, peritoneal, and ovarian metastases from breast cancer.
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case_images: PMC9643837_01_fonc-12-1013066-g003.jpg
case_images: f3
case_images: In addition to gastric metastasis, histopathological and immunohistochemical examinations of bilateral adnexectomy and peritoneal nodule confirmed that both the peritoneum and bilateral ovaries had metastases from breast cancer ( Figure 3 ).