case_images: PMC10704451_01
case_images: PMC10704451_02
case_images: Excerpt of vEEG showing a hyperkinetic seizure. The patient awoke from sleep, sat up abruptly, looked left, exhibited dystonia of the left lower limb, fumbled with hands involuntarily, arranged the quilt aimlessly, and exhibited confusion. The ictal EEG is characterized by a sudden decrease in the amplitude of each area on both sides at the beginning of the event, low amplitude fast waves, synchronous heart rate increase, and a myoelectric burst.
case_images: fneur-14-1280348-g001.jpg
case_images: PMC10704451_02_fneur-14-1280348-g001.jpg
case_images: fig1
case_images: The EEG during these episodes showed a sudden decrease in the amplitude of each area on both sides at the beginning of the event, low amplitude fast waves, synchronous heart rate increase, and a myoelectric burst (Figure 1). The father did not possess this mutation (Supplementary Figure S1).
case_images: Excerpt of vPSG showing one of the mixed arousal patterns of N3 sleep. The EEG characteristics of the first 3 s of a SWS interruption were mixed delta, theta, alpha, and beta activities.
case_images: fneur-14-1280348-g002.jpg
case_images: PMC10704451_02_fneur-14-1280348-g002.jpg
case_images: fig2
case_images: The duration and proportion of N3 sleep appeared reduced, with a SWS fragmentation index of 17.9/h, a mixed/slow awakening pattern of 3.6/h (Figure 2), and high values of cycle-alternating pattern (CAP) rates.