case_images: PMC8559630_01
case_images: Computed tomography image showing an 8.8 x1.6.8 x1 cm mass in the head of pancreas
case_images: cjim-12-407-g001.jpg
case_images: PMC8559630_01_cjim-12-407-g001.jpg
case_images: F1
case_images: Abdominal and pelvic computed tomography (CT) has been considered for confirming the diagnosis and heterogeneous enhancing mass lesion measured 8.8x1.6.8.x1 cm in the pancreas's head (figure 1) was reported accordingly.
case_images: PMC8559630_02
case_images: PMC8559630_03
case_images: Markedly pleomorphic tumor cells in diffuse sheets showed clouds of squamous cells with keratin pearls displaying in the hemorrhagic necrotic tissue (hematoxylin and eosin staining, magnification, x200)
case_images: cjim-12-407-g002.jpg
case_images: PMC8559630_03_cjim-12-407-g002.jpg
case_images: F2
case_images: Highly mitotic activity with atypical mitosis and granular eosinophilic cytoplasm was also observed (figure 2).
case_images: Histological finding showed a positive result for immunohistochemistry staining A, P63 marker B, CK5/6 marker (magnification, x400)
case_images: cjim-12-407-g003.jpg
case_images: PMC8559630_03_cjim-12-407-g003.jpg
case_images: F3
case_images: In addition, immunohistochemical (IHC) staining revealed that the samples were positive for CK5/6 and P63 markers, sensitive markers for squamous differentiation, which had confirmed our diagnosis (Figure 3).
case_images: PMC8559630_04
case_images: PMC8559630_05