case_images: PMC10955186_01
case_images: Multimodal imaging of a patient with focal choroidal excavation at initial presentation.. a. Color fundus photography of the left eye showing a yellow plaque-like foveal lesion. b. Fluorescein Angiography showing foveal hyperfluorescence without leakage c. Swept-source OCT in the macular region showing a foveal depression of the choroid and the complex Bruch's membrane-RPE (blue arrow). A localized foveal RPE atrophy was noted with a hypertransmission signal (white asterisk). The EZ was separated from the RPE by a hyperreflective material (yellow arrow) and a hyporeflective zone. The choroid appeared thinner in the area of the RPE depression than the parafoveal choroid which was a pachychoroid with pachyvessels. d.e.f.g. OCT-angiography showing a normal retinal vasculature with a foveal choriocapillaris flow void, corresponding to the thinned choroid beneath the FCE.. OCT: optical coherence tomography, RPE: retinal pigment epithelium, EZ: ellipsoid zone, SCP: superficial capillary plexus, DCP: deep capillary plexus.
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case_images: PMC10955186_01_f1000research-12-154513-g0000.jpg
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case_images: Fundus examination revealed the presence of a yellowish foveal lesion ( Figure 1). This multimodal imaging confirmed the diagnosis of a conforming FCE ( Figure 1).
case_images: Imaging before and after anti-VEGF treatment in a patient with FCE complicated with CNV.. a. Swept-source OCT showing intraretinal fluid with a foveal RPE detachment. b.c OCT-angiography at the level of the SCP (b) and the DCP (d) showing capillary disorganization and cystoid edema in the foveal region. d.e. OCT-angiography showing CNV at the level of the external retina (yellow arrow) and the choriocapillaris (blue arrow). f. Swept-source OCT two months after intravitreal injection of bevacizumab revealing normal aspect of the fovea with regular and intact RPE and resorption of the FCE. g.h. OCT-angiography at the level of the SCP (g) and the DCP (h) showing normalization of the retinal vasculature. i.j. Complete resorption of the CNV tissue on the external retina (i) and the choriocapillaris (j) on the OCT-angiography. The choriocapillaris showed persistence of the flow void in the foveal region corresponding to the localized choroidal thinning (white circle).. VEGF: vascular endothelial growth factor, FCE: focal choroidal excavation, CNV: choroidal neovascularization, OCT: optical coherence tomography, RPE: retinal pigment epithelium, SCP: superficial capillary plexus, DCP: deep capillary plexus.
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case_images: The OCT-angiography confirmed the presence of CNV ( Figure 2).