case_images: PMC10810171_01
case_images: Pancreatic panniculitis - example of numerous tender, erythematous, and violaceous subcutaneous nodules on the bilateral lower extremities
case_images: cureus-0016-00000052925-i01.jpg
case_images: PMC10810171_01_cureus-0016-00000052925-i01.jpg
case_images: FIG1
case_images: Erythematous and tender subcutaneous nodules were noted on the lower extremities (Figure 1). A punch biopsy of the right lower extremity demonstrated lobular panniculitis with necrotic adipocytes, basophilic debris, and calcification, consistent with PP (Figures 1, 3).
case_images: Pancreatic parenchyma with acute cellular rejection, grade II, with septal inflammation as activated lymphocytes involving septal structures and venulitis (subendothelial accumulation of inflammatory cells). Also shown is multifocal (but not confluent or diffuse) acinar inflammation (>=3 foci per lobule) with spotty acinar cell injury (power of field: 100x)
case_images: cureus-0016-00000052925-i02.jpg
case_images: PMC10810171_01_cureus-0016-00000052925-i02.jpg
case_images: FIG2
case_images: Both observations were made at a 100x power of field (Figure 2).
case_images: Hematoxylin and Eosin stain (100x) demonstrating ghosts of lipocytes surrounded by basophilic material and a mixed inflammatory cell infiltrate, consistent with pancreatic panniculitis
case_images: cureus-0016-00000052925-i03.jpg
case_images: PMC10810171_01_cureus-0016-00000052925-i03.jpg
case_images: FIG3
case_images: A punch biopsy of the right lower extremity demonstrated lobular panniculitis with necrotic adipocytes, basophilic debris, and calcification, consistent with PP (Figures 1, 3).