case_images: PMC10693421_01
case_images: Bronchoscopic examination shows (A) an irregular, protuberant mass at the orifice of RB7 on bronchoscopy, (B) a hybrid knife used to remove the tumor stump, (C) the appearance of the orifice of RB7, after a combined treatment of electrocautery snare, cryoresection, ESD using a hybrid knife, and APC for wound management, and (D) the appearance of the orifice of RB7 3-month post-treatment. (E) Hematoxylin and eosin staining shows the mass composed of spindle cells. Immunohistochemical staining reveals a (F) Ki-67 index of 3%+; the mass is positive for (G) alpha-smooth muscle actin, (H) desmin, and (I) vimentin.
case_images: fonc-13-1288044-g001.jpg
case_images: PMC10693421_01_fonc-13-1288044-g001.jpg
case_images: f1
case_images: Under general anesthesia, the bronchoscopy (BF-1T290; Olympus, Tokyo, Japan) conducted using a rigid bronchoscope revealed an irregular, protuberant mass at the orifice of RB7, which obstructed the lumen ( Figure 1A ). Subsequently, a hybrid knife (HybridKnife  ERBE JET2 Elektromedizin, Tubingen, Germany) was employed to dissect the tumor stump, as described previously ( Figure 1B ). After the tumor base resection, argon plasma coagulation (APC) was applied to treat the wound surface ( Figure 1C ). The 3-month and 5-month follow-up showed no signs of recurrence ( Figure 1D ). Hematoxylin and eosin staining indicated that the mass was composed of spindle cells ( Figure 1E ). Immunohistochemical staining revealed a relatively low Ki-67 proliferation index of 3%+ ( Figure 1F ), positive for alpha-smooth muscle actin, desmin, and vimentin ( Figures 1G-I ) and negative for HMB45 and S-100.