case_images: PMC10876304_01
case_images: (A) Kidney biopsy showing acute tubular injury with numerous granular casts (arrows) (H&E stain, 100x). (B) PAS-stained section showing a tubule containing granular cast material (PAS, 600x). (C) Multiple myoglobin casts staining positively by immunohistochemistry (IHC-stained section, 200x). (D) Very dark acellular material within tubules corresponding to myoglobin casts (electron microscopy photomicrograph, 3000x).
case_images: CRIN2024-6764335.001.jpg
case_images: PMC10876304_01_CRIN2024-6764335.001.jpg
case_images: fig1
case_images: There were many tubular granular eosinophilic casts (Figures 1(A) and 1(B)) which stained positively for myoglobin on immunohistochemistry (Figure 1(C)). Clumps of very dark acellular material were seen filling tubules, corresponding to the myoglobin casts seen on light microscopy (Figure 1(D)).