case_images: PMC11770369_01
case_images: (A) Non-contrast abdominal CT images revealed a large, poorly defined mass of slightly lower density in the right abdominal cavity. (B-D) Post-contrast images showed heterogeneous enhancement of the mass, with significant non-enhancing areas and prominent enhancing foci that appear to "float" within them.
case_images: fonc-14-1517710-g001.jpg
case_images: PMC11770369_01_fonc-14-1517710-g001.jpg
case_images: f1
case_images: Within the larger right mesenteric lesion, enhancing lesions appeared to "float" within the low-density area ( Figure 1 ).
case_images: (A) Hematoxylin and eosin staining (original magnification x200) showed oval and spindle-shaped tumor cells with varying cellular densities against a prominent mucinous matrix background, accompanied by small blood vessels and marked inflammatory cell infiltration. (B) Immunohistochemistry for ALK (original magnification x200) revealed a diffuse membranous staining pattern in tumor cells.
case_images: fonc-14-1517710-g002.jpg
case_images: PMC11770369_01_fonc-14-1517710-g002.jpg
case_images: f2
case_images: Microscopy revealed oval- and spindle-shaped tumor cells with varying cellular densities against a prominent mucinous matrix background, accompanied by small blood vessels and marked inflammatory cell infiltration ( Figure 2A ). Immunohistochemistry for ALK demonstrated diffuse positive expression of ALK in the tumor cells, with a distinctive nuclear membranous staining pattern ( Figure 2B ).
case_images: Follow-up abdominal CT scan: (A) Non-contrast abdominal CT images show a large amount of ascites, with unclear lesion contours. (B-D) Contrast-enhanced images reveal diffuse nodules and masses of varying sizes throughout the abdominal cavity, exhibiting markedly heterogeneous enhancement, with still noticeable non-enhancing areas, most of which are located at the center of the lesions.
case_images: fonc-14-1517710-g003.jpg
case_images: PMC11770369_01_fonc-14-1517710-g003.jpg
case_images: f3
case_images: A follow-up whole abdominal CT scan ( Figure 3 ) showed multiple nodules and mass shadows of varying sizes in the abdominal mesenteric area, peritoneum, and omentum, which were significantly increased compared to the previous CT images, suggesting tumor recurrence and seeding metastasis.