case_images: PMC11772169_01
case_images: CBA (cell-based assay): Serum samples were incubated with human embryonic kidney (HEK) transfected with CARP VIII. (A) A specific reaction was detected when HEK cells transfected with CARP VIII were incubated with patient serum. A specific fluorescence could be seen in the cytoplasm, as indicated by the arrows, revealed a positive reaction. (B) On the contrary, no specific fluorescence was observed in the cytoplasm after incubation with serum from healthy people, indicating a negative reaction.
case_images: fimmu-15-1480212-g001.jpg
case_images: PMC11772169_01_fimmu-15-1480212-g001.jpg
case_images: f1
case_images: Neurological examination found cerebrospinal fluid nucleated cell count 6x106/L, monocytes 83%, apocytes 17%, negative tests for Pandy assay, cerebrospinal fluid protein (179.4 mg/L), cerebrospinal fluid glucose (4.0 mmol/L), cerebrospinal fluid chloride (130.3 mmol/L), normal results for cerebrospinal fluid culture and cerebrospinal fluid mycoplasma pneumoniae antibody, negative results for serum and cerebrospinal fluid autoimmune encephalitis spectrum [anti-glutamic acid decarboxylase (GAD65) antibody IgG, anti-glutamate receptor (NMDA) antibody IgG, anti-glutamate receptor (AMPA1) antibody IgG, anti-glutamate receptor (AMPA2) antibody, anti-leucine rich glioma inactivated protein 1 (LGI 1) antibody IgG, anti-contacting associated protein 2 (CASPR2) antibody IgG, GABA B receptor antibody IgG, MOG antibody IgG], negative results for oligoclonal bands and anti-AQP4 antibody IgG, serum and cerebrospinal fluid autoimmune cerebellitis spectrum [Yo/CDR2 antibody IgG, anti-DNER antibody IgG, ITPR1 antibody IgG, CARP VIII antibody IgG, PCA-2 antibody IgG, anti-glutamic acid decarboxylase (GAD65) antibody IgG] suggested serum CARP VIII antibody IgG (+) 1: 10 ( Figure 1 ), and negative findings for cerebrospinal fluid (Tested by Hangzhou Oumeng WeiYi Medical Laboratory, cranial magnetic resonance imaging(MRI), cranial magnetic resonance venous imaging(MRV), cranialmagnetic resonance arterial imaging(MRA) and spinal cord magnetic resonance imaging(MRI) scan were unremarkable.