case_images: PMC11250398_01
case_images: Patient at time of initial presentation. Patient reported 17-month history of slow-growing mass above left eye which had recently undergone a period of rapid growth. Mass was firm and mobile, measuring 1.5 x 2.5 cm. a Anterior view. b Lateral view.
case_images: cde-2024-0016-0001-539123_F01.jpg
case_images: PMC11250398_01_cde-2024-0016-0001-539123_F01.jpg
case_images: F1
case_images: Examination revealed a 1.5 x 2.5 cm firm, mobile, mass at the lateral, left supraorbital rim, shown in Figure 1.
case_images: a-c Hematoxylin and eosin sections show a poorly circumscribed, asymmetrical tumor consisting of pleomorphic basaloid cells and eosinophilic shadow cells seen at the center of these basaloid islands (x4, a). Prominent nucleoli are also noted, with oftentimes mild cytologic atypia (x10, b, x20, c).
case_images: cde-2024-0016-0001-539123_F02.jpg
case_images: PMC11250398_01_cde-2024-0016-0001-539123_F02.jpg
case_images: F2
case_images: Histopathology revealed uniform basaloid cells and "ghost cells" in which only shadows of nuclei remained, basaloid cells with infiltrative patterns and aggregates with central necrosis, shown in Figures 2 and 3.
case_images: Beta-catenin positively stains basaloid tumor cells.
case_images: cde-2024-0016-0001-539123_F03.jpg
case_images: PMC11250398_01_cde-2024-0016-0001-539123_F03.jpg
case_images: F3
case_images: Histopathology revealed uniform basaloid cells and "ghost cells" in which only shadows of nuclei remained, basaloid cells with infiltrative patterns and aggregates with central necrosis, shown in Figures 2 and 3.
case_images: Mib1 (Ki-67) staining demonstrates a high proliferative index in the infiltrative areas and areas of necrosis.
case_images: cde-2024-0016-0001-539123_F04.jpg
case_images: PMC11250398_01_cde-2024-0016-0001-539123_F04.jpg
case_images: F4
case_images: Mib1 (Ki-67) showed a high proliferative index in the infiltrative areas and areas of necrosis, shown in Figure 4.
case_images: a Markings prior to MMS excision with planned margins of 0.5 cm. b Final defect measuring 2.5 cm x 3.5 cm. Of note, patient opted for healed by secondary intent.
case_images: cde-2024-0016-0001-539123_F05.jpg
case_images: PMC11250398_01_cde-2024-0016-0001-539123_F05.jpg
case_images: F5
case_images: Final defect measured 2.5 cm x 3.5 cm, shown in Figure 5.