case_images: PMC3859158_01
case_images: Coronal (a) and transverse (b) contrast-enhanced computed tomography (CT) scan showed a 9.2 x 9.5 x 11.5 cm, huge, and well-defined left suprarenal mass (arrow) arising either from adrenal gland, pancreas, or retroperitoneum. The mass demonstrated mild heterogeneous enhancement with central cystic/necrotic area. No evidence of lymphadenopathy or regional/distant metastasis was identified.
case_images: CRIM.ONCMED2013-416713.001.jpg
case_images: PMC3859158_01_CRIM.ONCMED2013-416713.001.jpg
case_images: fig1
case_images: No evidence of lymphadenopathy or regional/distant metastasis was identified (Figures 1(a) and 1(b)).
case_images: Microscopic examination of the pancreatic tail tumor. (a) Tumor was composed of monomorphic spindle-shaped Schwann cells with poorly defined eosinophilic cytoplasm and pointed basophilic nuclei set in a collagenous stroma. Focal nuclear palisading is noted (H&E stain, magnification power: 10x). (b) Areas characteristic for Antoni B composed of Schwann cells with inconspicuous cytoplasm and nuclei suspended in myxoid matrix are identified. Scattered degenerated nuclei in a hyalinized stroma suggestive of ancient schwannoma were present. No mitosis or necrosis was noted (H&E stain, magnification power: 40x).
case_images: CRIM.ONCMED2013-416713.002.jpg
case_images: PMC3859158_01_CRIM.ONCMED2013-416713.002.jpg
case_images: fig2
case_images: Focal nuclear palisading was noted (Figure 2(a)). No mitosis or necrosis was noted (Figure 2(b)).
case_images: Immunohistochemical examination of the pancreatic tail tumor showed diffuse and strong positivity to S100 protein (magnification power: 40x).
case_images: CRIM.ONCMED2013-416713.003.jpg
case_images: PMC3859158_01_CRIM.ONCMED2013-416713.003.jpg
case_images: fig3
case_images: Immunohistochemically, tumor cells stained diffusely and strongly positive for S100 protein (Figure 3).