case_images: PMC11770488_01
case_images: SD-OCT shows right eye pre (left photo) and post amniotic membrane graft surgery (right photo). Yellow arrow pointing to amniotic graft. Post surgery OCT showing integration of graft into inner retinal layers. Subretinal bubbles of perfluorocarbon can be seen in the superior macula of both images. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
case_images: gr1.jpg
case_images: PMC11770488_01_gr1.jpg
case_images: fig1
case_images: One month after his second surgery, the macular hole was still open (Fig. 1), VA was 20/60 eccentrically. OCT showed the DHACM integrated into the inner retina with the outer retinal layers underneath (Fig. 1).
case_images: Color fundus photos show right eye pre (top left) and post amniotic membrane removal (top right). SD-OCT shows right eye macular hole remains closed after amniotic membrane removal (bottom photo). Subretinal bubbles of perfluorocarbon in the superior macula seen in both images. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
case_images: gr2.jpg
case_images: PMC11770488_01_gr2.jpg
case_images: fig2
case_images: At his 1 week post-operative visit, his vision improved to 20/80 with a flat retina, closed macular hole, and restoration of macular layers on OCT (Fig. 2).
case_images: Excised fragment of amniotic tissue as provided by pathology lab.
case_images: gr3.jpg
case_images: PMC11770488_01_gr3.jpg
case_images: fig3
case_images: After 6 months of implantation, the 0.1cm fragment of hypocellular membranous amniotic tissue (Fig. 3) did not show obvious retinal tissue integration on multiple H&E-stained levels examined under high-magnification.