case_images: PMC4754484_01
case_images: CT scan of brain showing that the lesion has encircled both optic nerves.
case_images: CRINM2016-1972594.001.jpg
case_images: PMC4754484_01_CRINM2016-1972594.001.jpg
case_images: fig1
case_images: The final radiological impression was left parasellar meningioma (Figure 1).
case_images: Photomicrograph showing inflammatory nature of the lesion (H&E, x200).
case_images: CRINM2016-1972594.002.jpg
case_images: PMC4754484_01_CRINM2016-1972594.002.jpg
case_images: fig2
case_images: Microscopically, the tumour showed hyalinized fibrocollagenous tissue containing nodular collections of foamy histiocytes, lymphocytes, and plasma cells (Figure 2).
case_images: Photomicrograph of the lesion showing many histiocytes, some of which have engulfed intact lymphocytes (H&E, x400).
case_images: CRINM2016-1972594.003.jpg
case_images: PMC4754484_01_CRINM2016-1972594.003.jpg
case_images: fig3
case_images: A few foci showed emperipolesis (lymphophagocytosis by histiocytes) (Figure 3).
case_images: Photomicrograph of immunohistochemistry of the lesion showing positive reactivity of the histiocytes to S-100 protein (S-100, x400).
case_images: CRINM2016-1972594.004.jpg
case_images: PMC4754484_01_CRINM2016-1972594.004.jpg
case_images: fig4
case_images: Immunohistochemically, the emperipolesis histiocytes were positive for S-100 protein (Figure 4) and negative for AE1/AE3 (pan-cytokeratin), epithelial membrane antigen (EMA), vimentin, and estrogen receptor.