case_images: PMC11074827_01
case_images: The kidney biopsy findings. (a) Light microscopy shows minor glomerular abnormalities, mild interstitial edema, and vacuolar regeneration in some proximal tubular cells (arrow heads), a necrotic renal tubule (arrow), and tubular simplification (asterisk). Original magnification x200. Periodic acid-Schiff. (b) Electron microscopy shows diffuse foot process effacement and microvillous transformation of podocytes. Bar = 2.0 mum.
case_images: CRIN2024-1505583.001.jpg
case_images: PMC11074827_01_CRIN2024-1505583.001.jpg
case_images: fig1
case_images: The kidney biopsy revealed minor glomerular abnormalities, mild interstitial edema, and vacuolar regeneration in some proximal tubular cells and a few necrotic renal tubules (Figure 1(a)). Tubular simplification, including loss of brush border of the proximal tubule and dilated tubule with flattening of tubular epithelium, was also observed (Figure 1(a)). No immune reactant depositions were found in the immunofluorescence study, while electron microscopy showed diffuse foot process effacement (Figure 1(b)).
case_images: The clinical course after the onset of nephrotic syndrome. Arrow: steroid pulse therapy (500 mg of methylprednisolone given daily for 3 days); PSL: prednisolone; LDL-apheresis: low-density lipoprotein-apheresis; Alb: albumin; Cr: creatinine.
case_images: CRIN2024-1505583.002.jpg
case_images: PMC11074827_01_CRIN2024-1505583.002.jpg
case_images: fig2
case_images: Her clinical course is depicted in Figure 2.
case_images: The clinical course after the relapse of nephrotic syndrome. Arrow: steroid pulse therapy (500 mg of methylprednisolone given daily for 3 days); PSL: prednisolone; Alb: albumin; Cr: creatinine; NAG: urinary N-acetyl-beta-D-glucosaminidase; ualpha1MG: urinary alpha1-microglobulin.
case_images: CRIN2024-1505583.003.jpg
case_images: PMC11074827_01_CRIN2024-1505583.003.jpg
case_images: fig3
case_images: Her clinical course is illustrated in Figure 3.