case_images: PMC11374662_01
case_images: The NovoTTF-200A System.
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case_images: PMC11374662_01_fonc-14-1441146-g001.jpg
case_images: f1
case_images: A full timeline of the episode of care is shown in  Supplementary Figure 1 .
case_images: Computed tomography scan images. (A) Axial and coronal views at the time of initial diagnosis (May 2021) showing an avidly enhancing intra-axial mass in the right temporal lobe (maximal dimensions of 4.7 x 3.4 x 3.5 cm) with moderate surrounding vasogenic edema. (B) Post-operative axial computed tomography (May 2021). (C) Axial view with contrast enhancement while on treatment with Tumor Treating Fields (February 2022) showing stable disease. (D) Two slices of CT Axial views while on treatment with Tumor Treating Fields (May 2022) showing stable disease. No evidence of tumor is noted. (E) Two different level slices of CT Axial views. There is heterogenous and irregular contrast enhancement extending to the posterior right temporal lobe with vasogenic edema consistent with recurrence (August 2022).
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case_images: PMC11374662_01_fonc-14-1441146-g002.jpg
case_images: f2
case_images: Upon admission, his initial computed tomography (CT) scans revealed a right-sided temporal lobe mass (4.7 x 3.4 x 3.5 cm) suggestive of malignancy ( Figure 2A ) and he underwent a right temporal craniotomy for subtotal tumor resection ( Figure 2B ). Follow-up CT scans in February ( Figure 2C ) and May ( Figure 2D ) of 2022 were indicative of stable disease. The following CT scan in August 2022 ( Figure 2E ) revealed a significant increase in size of heterogeneously enhancing mass within the right temporal occipital lobe with surrounding vasogenic edema (11 mm left midline shift and mild right subfalcine herniation).
case_images: Specimens from pathology report. (A) Hematoxylin and eosin staining. (B) Glial fibrillary acidic protein. (C) Ki67.
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case_images: PMC11374662_01_fonc-14-1441146-g003.jpg
case_images: f3
case_images: The frozen specimen was consistent with GBM, and the final pathology confirmed a World Health Organization grade 4 GBM (2021 classification;  Figures 3A-C ).