case_images: PMC5465775_01
case_images: Purplish nodules on lower extremities.
case_images: cde-0009-0080-g01.jpg
case_images: PMC5465775_01_cde-0009-0080-g01.jpg
case_images: f1
case_images: Ten days later, she developed tender erythematous nodules and plaques on her upper and lower extremities as well as on the abdomen, clinically suggestive of erythema nodosum-like lesions (Fig. 1).
case_images: Hemalun eosin, x50 magnification. The infiltrate occurred in fat lobules.
case_images: cde-0009-0080-g02.jpg
case_images: PMC5465775_01_cde-0009-0080-g02.jpg
case_images: f2
case_images: Histopathological examination showed no specific perivascular lymphohistiocytic infiltrate in the superficial dermis, but in the deep dermis and hypodermis the infiltrate was composed with a predominance of neutrophils (Fig. 2).
case_images: Hemalun eosin, x400 magnification. A: Inflammatory compounds (containing polymorphonuclear neutrophils) surrounding hypodermis capillary walls. B: Fibrinoid necrosis of a vascular wall.
case_images: cde-0009-0080-g03.jpg
case_images: PMC5465775_01_cde-0009-0080-g03.jpg
case_images: f3
case_images: In hypodermis, these neutrophils were located in fat lobules and surrounded some capillary walls with fibrinoid necrosis and nuclear debris (Fig. 3).