case_images: PMC10495986_01
case_images: Fine needle aspiration from level 11L showing occasional non-caseating granulomas. There was no evidence of melanoma. (A, B): Diff-Quik stain, 400x)0.
case_images: fonc-13-1217179-g001.jpg
case_images: PMC10495986_01_fonc-13-1217179-g001.jpg
case_images: f1
case_images: Endobronchial biopsy of station 11L lymph nodes demonstrated polymorphous lymphocyte population and rare non-necrotizing granulomas ( Figure 1 ).
case_images: PMC10495986_02
case_images: Core biopsy from right inguinal lymph node demonstrating well-formed, non-caseating granulomas. There was no evidence of melanoma. (H&E, 100x).
case_images: fonc-13-1217179-g002.jpg
case_images: PMC10495986_02_fonc-13-1217179-g002.jpg
case_images: f2
case_images: Given proximity to original presentation, biopsy was pursued and demonstrated non-caseating granulomatous inflammation consistent with sarcoidosis ( Figure 2 ).
case_images: Case 2 PET progression. (A) Baseline PET scan on 30/05/2019 showing a large right inguinal mass and prominent subcarinal node with SUV max 2.9. (B) PET 28/08/2020, after completion of adjuvant therapy showing postsurgical changes in the right thigh and resolved FDG uptake of the subcarinal lymph node. (C) 21/07/2021 representative surveillance PET with mediastinal, abdominal, retroperitoneal, and right iliac lymph nodes (biopsy). (D) 28/06/2023, most recent PET. Postsurgical changes without abnormal lymphadenopathy. This patient received no sarcoid-directed therapy over this course.
case_images: fonc-13-1217179-g003.jpg
case_images: PMC10495986_02_fonc-13-1217179-g003.jpg
case_images: f3
case_images: A similar pattern of waxing and waning adenopathy persisted through the last follow-up in June 2023 ( Figure 3 ).