case_images: PMC9529482_01
case_images: Original magnification x40 hematoxylin and eosin stain, depicting thickened muscularis propria with an area of mucosa herniation through the muscularis propria (Rokitansky-Aschoff sinuse) and accompanying exuberant inflammatory infiltrate.
case_images: CRIPA2022-2956052.001.jpg
case_images: PMC9529482_01_CRIPA2022-2956052.001.jpg
case_images: fig1
case_images: On microscopic exam, the specimen showed chronic cholecystitis with exuberant inflammatory infiltrate (Figure 1).
case_images: Original magnification x400 hematoxylin and eosin stain, depicting a mural vessel with intraluminal large mononucleated cells with occasional folding of the nuclear membranes, open chromatin, and an inconspicuous red nucleoli, representing immature precursors.
case_images: CRIPA2022-2956052.002.jpg
case_images: PMC9529482_01_CRIPA2022-2956052.002.jpg
case_images: fig2
case_images: On careful examination, atypical cells with vesicular chromatin, folded nuclei, and inconspicuous red nucleoli were noted percolating into the gallbladder wall and lining vascular spaces (Figure 2).
case_images: Original magnification x400 CD43 immunohistochemical stain, depicting CD43 membranous staining of the intravascular immature precursors.
case_images: CRIPA2022-2956052.003.jpg
case_images: PMC9529482_01_CRIPA2022-2956052.003.jpg
case_images: fig3
case_images: These cells were positive for CD117, CD43 (Figure 3), and myeloperoxidase (Figure 4) stains and negative for CD20 and CD3 stains.
case_images: Original magnification x400 myeloperoxidase immunohistochemical stain, depicting characteristic granular cytoplasmic staining of myeloperoxidase in the intravascular immature precursors.
case_images: CRIPA2022-2956052.004.jpg
case_images: PMC9529482_01_CRIPA2022-2956052.004.jpg
case_images: fig4
case_images: These cells were positive for CD117, CD43 (Figure 3), and myeloperoxidase (Figure 4) stains and negative for CD20 and CD3 stains.