case_images: PMC4617150_01
case_images: Summary of exome sequencing results comparing tumor and control skin tissue displayed as a Circos diagram. The outermost ring indicates chromosomes. The next ring summarizes DNA copy number and shows a scatter plot of the log2 ratio of normalized DNA concentration (RPKM) in the tumor and normal samples (red points). The green points indicate the inferred segmented copy number profile. The third ring from the outermost summarizes variant allele frequencies across the chromosomes (red points) and segmented allele frequencies (green points). The innermost ring indicates the positions of somatic SNP (circles) and indels (triangles). Somatic mutations likely to lead to a change in an encoded protein are colored green and those that are also included in the Cancer Gene Census list are colored red. All other somatic mutations are colored gray.
case_images: fonc-05-00236-g001.jpg
case_images: PMC4617150_01_fonc-05-00236-g001.jpg
case_images: F1
case_images: Second pathological review at our center found the presence of rhabdoid cells in over 90% of the tumor material (Figure S1A in Supplementary Material) and negative immunostaining for INI-1 within the tumor except for intratumoral blood vessels (Figure S1B in Supplementary Material).