case_images: PMC4006558_01
case_images: Clinical picture at time of first presentation and histological stains ((a) right breast, (b) cytokeratin 7 stain, (c) HE stain, and (d) left breast).
case_images: CRIDM2014-152836.001.jpg
case_images: PMC4006558_01_CRIDM2014-152836.001.jpg
case_images: fig1
case_images: A 72-year-old woman (para 1) was seen with erythematous and eczematous patches that developed simultaneously on both nipples and had been present for 2.5 years (Figures 1(a) and 1(d)). The histopathology showed epidermal cells with hyperchromatic and polymorphic nuclei, intraepithelial gland cells (Figure 1(b)), and a high expression of cytokeratin 7 (Figure 1(c)), so-called Paget's cells.