case_images: PMC5437434_01
case_images: Clinical appearance before and after therapy. Ventral trunk (a), dorsal trunk (b), face(c), and hypertrophic verrucous vegetative plaques on the armpit (d).
case_images: cde-0009-0145-g01.jpg
case_images: PMC5437434_01_cde-0009-0145-g01.jpg
case_images: F1
case_images: BMI of 13.01. Blisters, erosions, and hemorrhagic crusts with hypertrophic verrucous vegetative plaques were found on the armpits, trunk, extremities, and in the perianal region (Fig. 1).
case_images: a Histopathological results of the vegetating lesions on the extremities revealed a suprabasal cleft with scattered acantholytic cells and hyperkeratosis. The subepithelial layer was filled with lymphocytes (hematoxylin and eosin. x100). b Direct immunofluorescence staining (DIF) showed deposits of immunoglobulin G (green color) in the epidermal intracellular spaces, which is characteristic of pemphigus (DIF. x400).
case_images: cde-0009-0145-g02.jpg
case_images: PMC5437434_01_cde-0009-0145-g02.jpg
case_images: F2
case_images: The subepithelial layer was filled with lymphocytes (Fig. 2a). Direct immunofluorescence (DIF) staining showed deposits of immunoglobulin G on the surface of the keratinocytes (Fig. 2b), which supported the diagnosis of pemphigus vegetans.