case_images: PMC8248351_01
case_images: Brain CT and MRI findings of the case. (A) CT scan taken at 1 month after birth shows a focal calcification in the right thalamus. MRI [(B-D) T2WI, (E) FLAIR, (F) contrast-enhanced sequence] taken at 4 years and 1 month of age demonstrates bilateral calcifications and cysts, some with contrast enhancement, in the periventricular regions, basal ganglia, right thalamus, and pons, along with increased T2/FLAIR signal changes in periventricular white matter.
case_images: fneur-12-585606-g0001.jpg
case_images: PMC8248351_01_fneur-12-585606-g0001.jpg
case_images: F1
case_images: The first onset of his seizure was at 10 days after birth, and his initial brain CT taken at 1 month of age showed a focal calcification in the right thalamus (Figure 1A). Increased T2/FLAIR (fluid-attenuated inversion recovery) signal was also identified in periventricular white matter (Figures 1B-F).
case_images: Patient's timeline of seizures and the following treatment. Patient's seizures periods were highlighted in yellow. The dosages of LEV treatment are shown under the diagram of disease onset. // was used to omit the time intervals that have no changes in clinical display or treatment.
case_images: fneur-12-585606-g0002.jpg
case_images: PMC8248351_01_fneur-12-585606-g0002.jpg
case_images: F2
case_images: The boy continued to receive oral antiepileptic treatment with levetiracetam (250 mg in the morning and 375 mg at night, Q12h, about 28 mg/kg/day) (Figure 2).