case_images: PMC10350867_01
case_images: Findings at the initial examination (the day after vaccination). BCVA was 0.03 in the right eye and 1.0 in the left eye. Color fundus photographs showed retinal vasculitis with sheathing of the arteries and veins (suggestive of FBA), retinal blot hemorrhages, and vitreous haze grade 1+ in both eyes (a). Fluorescein angiography revealed dye staining and slight leakage from retinal veins, with leakage of the optic disc and a non-perfusion area in the peripheral fundus in the right eye (b). Optical coherence tomography of the macula showed retinal edema and retinal detachment in the right eye (c).
case_images: cop-2023-0014-0001-530794_F01.jpg
case_images: PMC10350867_01_cop-2023-0014-0001-530794_F01.jpg
case_images: F1
case_images: Funduscopic examination revealed grade 1+ vitreous haze and severe retinal vasculitis, with sheathing of the artery and vein in both eyes (Fig. 1a), suggestive of FBA. Fluorescein angiography revealed dye staining and slight leakage from the retinal veins in both eyes (Fig. 1b). Optical coherence tomography of the macula showed retinal edema and retinal detachment in the right eye (Fig. 1c).
case_images: Findings at 1 day after the initial visit (2 days after the patient had received the third dose of the COVID-19 vaccine). BCVA was 0.03 in the right eye and 0.08 in the left eye. Color fundus photographs showed worsening retinal vasculitis in both eyes but especially in the left eye (a). Retinal edema also had developed in the left eye (b).
case_images: cop-2023-0014-0001-530794_F02.jpg
case_images: PMC10350867_01_cop-2023-0014-0001-530794_F02.jpg
case_images: F2
case_images: Funduscopic findings revealed expanded retinal vasculitis and development of macular edema in the left eye (Fig. 2).
case_images: Findings after 2 courses of pulse steroid therapy and intravenous infusion of acyclovir (20 days after COVID-19 vaccination). BCVA was 0.15 in the right eye and 0.6 in the left eye. Color fundus photographs showed that sheathing of retinal vessels was improving, and macular edema had disappeared. FBA after mRNA COVID-19 vaccination.
case_images: cop-2023-0014-0001-530794_F03.jpg
case_images: PMC10350867_01_cop-2023-0014-0001-530794_F03.jpg
case_images: F3
case_images: The second course was successful, and the funduscopic findings improved (Fig. 3).