case_images: PMC6302271_01
case_images: Cisternal cerebrospinal fluid (CSF) white blood cell count. CSF analyses were conducted every 1 to 3 months. Normal limit: <5 cells/cm2 (red line).
case_images: 10.1177_2324709618820047-fig1.jpg
case_images: PMC6302271_01_10.1177_2324709618820047-fig1.jpg
case_images: fig1-2324709618820047
case_images: Despite 42 years of therapy, longitudinal CSF studies reveal persistent lymphocytic pleocytosis (Figure 1), elevated protein (Figure 2), normalizing glucose (Figure 3), and persistent complement fixation titers (Figure 4).
case_images: Cisternal cerebrospinal fluid (CSF) protein. CSF analyses were conducted every 1 to 3 months. Normal values: 15 (red) to 45 (green) mg/dL.
case_images: 10.1177_2324709618820047-fig2.jpg
case_images: PMC6302271_01_10.1177_2324709618820047-fig2.jpg
case_images: fig2-2324709618820047
case_images: Despite 42 years of therapy, longitudinal CSF studies reveal persistent lymphocytic pleocytosis (Figure 1), elevated protein (Figure 2), normalizing glucose (Figure 3), and persistent complement fixation titers (Figure 4).
case_images: Cisternal cerebrospinal fluid (CSF) glucose. CSF analyses were conducted every 1 to 3 months. Normal values: 40 (red) to 75 (green) mg/dL.
case_images: 10.1177_2324709618820047-fig3.jpg
case_images: PMC6302271_01_10.1177_2324709618820047-fig3.jpg
case_images: fig3-2324709618820047
case_images: Despite 42 years of therapy, longitudinal CSF studies reveal persistent lymphocytic pleocytosis (Figure 1), elevated protein (Figure 2), normalizing glucose (Figure 3), and persistent complement fixation titers (Figure 4).
case_images: Serological complement fixation titers. Cerebrospinal fluid analyses were conducted every 1 to 3 months.
case_images: 10.1177_2324709618820047-fig4.jpg
case_images: PMC6302271_01_10.1177_2324709618820047-fig4.jpg
case_images: fig4-2324709618820047
case_images: Despite 42 years of therapy, longitudinal CSF studies reveal persistent lymphocytic pleocytosis (Figure 1), elevated protein (Figure 2), normalizing glucose (Figure 3), and persistent complement fixation titers (Figure 4).
case_images: Serum fluconazole level. Cerebrospinal fluid analyses were conducted every 1 to 3 months. Currently, there is no universally accepted therapeutic serum level. At Kern Medical, the Division of Infectious Diseases accepts serum fluconazole levels of 30 (red) to 80 (green) microg/mL.
case_images: 10.1177_2324709618820047-fig5.jpg
case_images: PMC6302271_01_10.1177_2324709618820047-fig5.jpg
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case_images: Serum fluconazole levels have been routinely collected (Figure 5).