case_images: PMC6196920_01
case_images: Chest CT scan showing bilateral ground glass opacities and nodular densities.
case_images: CRIHEM2018-3821392.001.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.001.jpg
case_images: fig1
case_images: He had a computed tomography (CT) scan of the chest which showed bilateral ground glass opacities predominantly in the upper lobes with increased nodularity and small-volume mediastinal lymphadenopathy (Figure 1).
case_images: Atypical lymphocytes in the vessels (100x).
case_images: CRIHEM2018-3821392.002.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.002.jpg
case_images: fig2
case_images: Pathologic examination of the wedge resection of the lung showed expanded pulmonary interstitium by atypical, discohesive lymphoid cells within alveolar capillaries on routine hematoxylin and eosin staining (Figures 2 and 3).
case_images: Hematoxylin-eosin staining atypical lymphocytes in the capillaries (20x).
case_images: CRIHEM2018-3821392.003.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.003.jpg
case_images: fig3
case_images: Pathologic examination of the wedge resection of the lung showed expanded pulmonary interstitium by atypical, discohesive lymphoid cells within alveolar capillaries on routine hematoxylin and eosin staining (Figures 2 and 3).
case_images: Hematoxylin-eosin staining showing angiotropism of medium size vessel.
case_images: CRIHEM2018-3821392.004.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.004.jpg
case_images: fig4
case_images: These atypical lymphoid cells also demonstrated angiotropism/angioinvasion of the medium sized pulmonary vessels (Figure 4).
case_images: CD20 immunostaining showing intravascular atypical lymphoid cells.
case_images: CRIHEM2018-3821392.005.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.005.jpg
case_images: fig5
case_images: Immunohistochemical (IHC) staining (DAKO platform) showed that the atypical lymphoid cells were positive for CD20 (Figures 5 and 6), CD79A, Pax5, BCL2, MUM1, BCL6 (more than 30%), and CD10 (focal; less than 10%).
case_images: CD20 immunostain showing angiotropism of medium size vessels by atypical lymphoid cells.
case_images: CRIHEM2018-3821392.006.jpg
case_images: PMC6196920_01_CRIHEM2018-3821392.006.jpg
case_images: fig6
case_images: Immunohistochemical (IHC) staining (DAKO platform) showed that the atypical lymphoid cells were positive for CD20 (Figures 5 and 6), CD79A, Pax5, BCL2, MUM1, BCL6 (more than 30%), and CD10 (focal; less than 10%).