case_images: PMC11802409_01
case_images: (A-F) The report of the colonoscope describes scattered ulcers, scars, and polypoid hyperplasia observed in the mucosa. (G-I) Microscopic images of the patient's colon tissue section revealed colonic mucosa with crypt abscesses, crypt architectural distortion, and expansion of the lamina propria with mixed inflammatory cell infiltration (hematoxylin&eosin, G, magnification x100, H,I, magnification x 200).
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case_images: PMC11802409_01_fmed-11-1507524-g001.jpg
case_images: fig1
case_images: The report of the colonoscope describes scattered ulcers, scars, and polypoid hyperplasia observed in the mucosa (Figures 1A-F). Microscopic images of the patient's colon tissue section reveal crypt distortion and abscesses (Figures 1G-I).
case_images: (A,B) Multiple scaly erythematous eruptions and pustules on the ankles, lower legs, knees, elbows, palms, and soles. (C) Histology showing epidermal psoriasiform hyperplasia, Kogoj's micro-abscesses and spongiotic vesicle in the epidermis (hematoxylin&eosin, magnification x40). (D) Eosinophils observed in the dermis (hematoxylin&eosin, magnification x400).
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case_images: PMC11802409_01_fmed-11-1507524-g002.jpg
case_images: fig2
case_images: Four months after initiating adalimumab treatment, the patient developed multiple scaly erythematous eruptions and pustules on the ankles, lower legs, knees, elbows, palms, and soles (Figures 2A,B). A skin biopsy of the plaque was performed revealing epidermal psoriasiform hyperplasia, Kogoj's micro-abscesses and spongiotic intraepidermal vesicle, and neutrophils in the vesicle, eosinophils observed in the dermis (Figures 2C,D).
case_images: Timeline of the patient's diagnosis with the relevant data about the treatment and follow-up.
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case_images: PMC11802409_01_fmed-11-1507524-g003.jpg
case_images: fig3
case_images: Four months later, the patient's psoriatic lesions resolved, and his CD entered remission (Figure 3).