case_images: PMC4118727_01
case_images: Gross-grey white mass.
case_images: can-8-447fig1.jpg
case_images: PMC4118727_01_can-8-447fig1.jpg
case_images: figure1
case_images: The cut surface was grey-white solid homogeneous [Figure 1].
case_images: M/E showing squamous and spindle cell component (H & E Stain; 10x).
case_images: can-8-447fig2.jpg
case_images: PMC4118727_01_can-8-447fig2.jpg
case_images: figure2
case_images: Microscopic examination revealed a tumour composed of proliferating atypical bipolar spindle cells and small nests of squamous epithelial cells [Figure 2].
case_images: M/E showing spindle cells arranged in fascicles (H & E Stain; 10x).
case_images: can-8-447fig3.jpg
case_images: PMC4118727_01_can-8-447fig3.jpg
case_images: figure3
case_images: Malignant spindle cells, arranged in fascicles [Figures 3 and 4], formed the main bulk of the tumour.
case_images: M/E showing spindle cell component (H & E Stain; 40x).
case_images: can-8-447fig4.jpg
case_images: PMC4118727_01_can-8-447fig4.jpg
case_images: figure4
case_images: Malignant spindle cells, arranged in fascicles [Figures 3 and 4], formed the main bulk of the tumour.
case_images: M/E showing epithelial pearl (H & E Stain; 10x).
case_images: can-8-447fig5.jpg
case_images: PMC4118727_01_can-8-447fig5.jpg
case_images: figure5
case_images: At a few foci, small nests of malignant squamous epithelial cells and epithelial pearls were seen [Figure 5].
case_images: IHC showing spindle cells strongly positive for vimentin (10x).
case_images: can-8-447fig6.jpg
case_images: PMC4118727_01_can-8-447fig6.jpg
case_images: figure6
case_images: On immunohistochemistry, vimentin was strongly positive in the spindle cell component [Figure 6] and negative in the epithelial component.
case_images: IHC showing spindle cells focal positivity for cytokeratin (10x).
case_images: can-8-447fig7.jpg
case_images: PMC4118727_01_can-8-447fig7.jpg
case_images: figure7
case_images: Cytokeratin was focally positive in spindle cell component [Figure 7] and strongly positive in the epithelial component [Figure 8].
case_images: IHC showing squamous cells positive for cytokeratin (10x).
case_images: can-8-447fig8.jpg
case_images: PMC4118727_01_can-8-447fig8.jpg
case_images: figure8
case_images: Cytokeratin was focally positive in spindle cell component [Figure 7] and strongly positive in the epithelial component [Figure 8].