case_images: PMC10622596_01
case_images: Homogeneous ANA IFA pattern:cytoplasmic speckled titer 1/80.
case_images: CRIPS2023-5260208.001.jpg
case_images: PMC10622596_01_CRIPS2023-5260208.001.jpg
case_images: fig1
case_images: ANA with a homogenous pattern and cytoplasmic dense fine speckled titer 1/80 (Figure 1). In addition, the dsDNA test was positive (Figure 2). ANA profile was examined using euroline ANA profile three panels plus DFS70 showed strong positive for antinucleosome (++), antihistones (+++), anti-AMA-M2 (+++), and borderline for anti-RNP/Sm, PM-Scl100 (PM 100), and anti-dsDNA and negative for anti-Sm, SSA, Ro-52, SSB, Scl-70, Jo-1, centromere B, PCNA, and ribosomal protein (RIB).
case_images: Results of ANA examination using the cytobead method. (a) Compartment 1 is negative (using tiny beads to detect anti-La/SSB and large beads for CENPB). (b) Compartment 2 is negative (using tiny beads to detect anti-Sm and large beads for RNP Sm). (c) Compartment 3 is positive for tiny beads, which means positive for anti-Ds-DNA (using small beads to detect anti-dsDNA and large beads for Scl-70). (d) Compartment 4 negatives (using tiny beads to detect anti-Ro-60 and large beads for RO-52). Red arrow: reference bead; blue arrow: positive beads.
case_images: CRIPS2023-5260208.002.jpg
case_images: PMC10622596_01_CRIPS2023-5260208.002.jpg
case_images: fig2
case_images: ANA with a homogenous pattern and cytoplasmic dense fine speckled titer 1/80 (Figure 1). In addition, the dsDNA test was positive (Figure 2). ANA profile was examined using euroline ANA profile three panels plus DFS70 showed strong positive for antinucleosome (++), antihistones (+++), anti-AMA-M2 (+++), and borderline for anti-RNP/Sm, PM-Scl100 (PM 100), and anti-dsDNA and negative for anti-Sm, SSA, Ro-52, SSB, Scl-70, Jo-1, centromere B, PCNA, and ribosomal protein (RIB).