case_images: PMC10823013_01
case_images: PET-CT highlighting metastatic TNBC with spread to the neck, sternum, thoracic spine, upper abdomen, and pelvis.
case_images: fonc-13-1305584-g001.jpg
case_images: PMC10823013_01_fonc-13-1305584-g001.jpg
case_images: f1
case_images: A PET/CT dated 31/01/2023 showed a right hypermetabolic breast mass of 2.5 cm x 1.9 cm with extensive adenopathy in the neck, chest, pelvic, and upper abdomen ( Figure 1 ).
case_images: CT scan with contrast showing marked hepatosplenomegaly.
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case_images: PMC10823013_01_fonc-13-1305584-g002.jpg
case_images: f2
case_images: Figure 2 ) without discrete lesions, which caused abdominal pain and bloating. Further workup failed to identify biliary ductal obstruction.
case_images: Total bilirubin over course of inpatient stay.
case_images: fonc-13-1305584-g003.jpg
case_images: PMC10823013_01_fonc-13-1305584-g003.jpg
case_images: f3
case_images: The patient experienced remarkable clinical response, with total bilirubin dropping steadily and liver function testing improving daily ( Figure 3 ).
case_images: Timeline of relevant clinical events (2022-2023).
case_images: fonc-13-1305584-g004.jpg
case_images: PMC10823013_01_fonc-13-1305584-g004.jpg
case_images: f4
case_images: CT 11/08/2023 showed stable hepatomegaly and splenomegaly and stable bone metastasis. Clinically patient is doing well with ECOG PS of 0, lab work showed platelet count of 128k/UL, total bilirubin 1.2 mg/dl, AST 62 U/L, ALT 69 U/L without additional growth factor support ( Figure 4 ).