case_images: PMC11362092_01
case_images: A CT of the neck revealed a solid lesion in the left thyroid lobe causing tracheal compression and deviation with endotracheal intubation.
case_images: fendo-15-1349114-g001.jpg
case_images: PMC11362092_01_fendo-15-1349114-g001.jpg
case_images: f1
case_images: Contrast-enhanced computed tomography of the neck revealed a solid lesion in the left thyroid lobe causing tracheal compression and deviation, with endotracheal intubation ( Figure 1 ).
case_images: Pathological examination: (A) The tumor cells are cuboidal, mostly polygonal, with abundant cytoplasm filled with eosinophilic granular substances. The nuclei vary in size, being round, oval, or irregular in shape, with deep chromatin staining. Nuclear division can be seen, and nucleoli are visible in some areas. The cell boundaries are clear. The tumor cells are arranged in a follicular or trabecular pattern, with the follicular structure being predominant. There are areas with unevenly thickened colloid inside the follicular cavity. (B) Capsular invasion is visible, and outside the capsule, there are tumor cell nodules of varying sizes. (C) Tumor thrombi can be seen inside the vessels. (D) Focal necrosis is visible. (E) Immunohistochemistry for TTF-1 is positive. (F) Immunohistochemistry for TG is positive.
case_images: fendo-15-1349114-g002.jpg
case_images: PMC11362092_01_fendo-15-1349114-g002.jpg
case_images: f2
case_images: Immunohistochemistry demonstrated positive staining for CK19, TG, TTF-1, and CD56, negative staining for Galectin-3 and TPO, and positive CD34 vascular staining ( Figure 2 ).