case_images: PMC11722611_01
case_images: Patient 1 before treatment with anifrolumab. A and B, Forearms with annular erythematous plaques with surrounding scale. C, Anterior thighs and shins with scattered, annular erythematous papules, and plaques with surrounding scale.
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case_images: fig1
case_images: A 70-year-old woman with a history of chronic kidney disease and hypothyroidism presented with polycyclic, pink, scaly plaques on all extremities and trunk in a predominantly photo-distributed pattern (Fig 1).
case_images: Patient 1 at follow-up after 2 infusions of anifrolumab (A) Forearms with postinflammatory erythema. B, Anterior thighs and shins with improving resolution of scale and deep erythema.
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case_images: fig2
case_images: Physical examination showed postinflammatory erythema (Fig 2).
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case_images: Patient 2 before treatment with anifrolumab. A, Erythematous papules and plaques. B, Upper chest with grouped erythematous papules and nodules.
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case_images: fig3
case_images: A 48-year-old woman presented with a longstanding history of nontender erythematous dermal plaques on the cheeks, forehead, and upper chest (Fig 3).
case_images: Patient 2 at after 2 infusions of anifrolumab. A, Face with resolution of papules and plaques. B, Upper chest resolution of papules and plaques and mild postinflammatory erythema.
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case_images: fig4
case_images: After 2 monthly infusions of anifrolumab 300 mg, the patient experienced complete resolution (Fig 4) without new flares.
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case_images: Patient 3 before treatment with anifrolumab. A, Posterior shoulder with nodules and adjacent hyperpigmented scars at prior biopsy sites. B,Lower cheek with atrophy and upper cheek with nodules.
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case_images: fig5
case_images: A 41-year-old woman presented with nodules and atrophic plaques on the shoulder and cheek (Fig 5).
case_images: Patient 3 after 3 infusions of anifrolumab. A, Posterior shoulder with postinflammatory hyperpigmentation and resolution of nodules. B,Lower cheek with atrophy and upper cheek with atrophy, postinflammatory hyperpigmentation, and resolution of nodules.
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case_images: fig6
case_images: Following 3 monthly infusions of anifrolumab 300 mg, the patient demonstrated significant improvement in nodules, with follow-up examination demonstrating postinflammatory pigmentary change and atrophy (Fig 6).