case_images: PMC10828972_01
case_images: Histological findings show diffuse crescentic necrotizing glomerulonephritis with endocapillary proliferation and full-house immune complex deposition. Glomerulus with cellular crescent (arrow), endocapillary crescent and fibrinoid necrosis by light microscopy, Masson's trichrome stain (A). Direct immunofluorescence demonstrates granular mesangial and capillary wall staining deposits of IgG (B), IgM (C), IgA (D), C3 (E), C1q (F), Fibrinogen (G), Kappa (H) e Lambda (I). Note the crescent surrounding the vascular tuft. Electron microscopy from paraffin embedded tissue reveals electron-dense deposits in the subendothelial (J) and mesangial (K) regions.
case_images: fimmu-14-1298622-g001.jpg
case_images: PMC10828972_01_fimmu-14-1298622-g001.jpg
case_images: f1
case_images: A renal biopsy revealed a proliferative and necrotizing glomerulonephritis with a full house immunofluorescence pattern, leading to the suspicion of lupus nephritis ( Figure 1 ).
case_images: Timeline of clinical evolution. The time and initial symptoms are specified from COVID-19 vaccination, investigation, treatment and patient outcome.
case_images: fimmu-14-1298622-g002.jpg
case_images: PMC10828972_01_fimmu-14-1298622-g002.jpg
case_images: f2
case_images: The timeline of the patient's evolution is shown in  Figure 2 .