case_images: PMC9376313_01
case_images: Light brown plaques were seen on the chest and abdomen (A), back (B), shoulder (C), and left upper arm (D).
case_images: fneur-13-874613-g0001.jpg
case_images: PMC9376313_01_fneur-13-874613-g0001.jpg
case_images: F1
case_images: Systemic examination revealed a light brown plaque with clear boundaries of different sizes scattered on the chest and abdomen, back, shoulder, and left upper arm, not protruding from the skin surface, and with a diameter of 0.3-8.0 cm (Figure 1).
case_images: MRI showed multiple abnormal signal foci in bilateral basal ganglia, thalamus, and pons.
case_images: fneur-13-874613-g0002.jpg
case_images: PMC9376313_01_fneur-13-874613-g0002.jpg
case_images: F2
case_images: MRI of the head revealed multiple abnormal signal foci in the bilateral basal ganglia, thalamus, and pons (Figure 2).
case_images: (A) Pedigree of the family affected with NF1. (B) Sequencing results of the NF1 mutation.
case_images: fneur-13-874613-g0003.jpg
case_images: PMC9376313_01_fneur-13-874613-g0003.jpg
case_images: F3
case_images: Q514Rfs*) in the NF1 gene in the proband and his mother (Figure 3). The same mutation was not detected in the proband's father (Figure 3).