case_images: PMC3764967_01
case_images: Abdominal CT images. a Before ERT. Liver size: 23.3 x 15.4 x 20.3 cm. Spleen size: 12.8 x 10.5 x 21.1 cm. b 5 months after ERT started. Liver size: 22.1 x 15.3 x 17.9 cm. Spleen size: 11.8 x 9.4 x 17.3 cm.
case_images: crg-0007-0340-g01.jpg
case_images: PMC3764967_01_crg-0007-0340-g01.jpg
case_images: F1
case_images: The splenic and the superior mesenteric vein were dilated and tortuous, whereas no apparent cirrhotic change of the liver was observed (fig. 1a). Figure 1b shows the CT scan 5 months after ERT started.
case_images: Microscopic findings of liver biopsy specimen. a, b Gaucher cells in Glisson's capsule (Elastica-Masson, a x40, b x400). c Arrowheads indicate the assembly of Gaucher cells in Glisson's capsule (hematoxylin and eosin, x200). d The cytoplasm of Gaucher cells is well stained with periodic acid-Schiff (x400).
case_images: crg-0007-0340-g02.jpg
case_images: PMC3764967_01_crg-0007-0340-g02.jpg
case_images: F2
case_images: The liver biopsy specimen showed that numerous large cells with striated cytoplasm assembled in Glisson's capsule (fig. 2).
case_images: Changes in platelets count and ACE concentration during the course of ERT.
case_images: crg-0007-0340-g03.jpg
case_images: PMC3764967_01_crg-0007-0340-g03.jpg
case_images: F3
case_images: Platelet counts number and ACE concentration, a biomarker of the progress of Gaucher disease, were also improved from 7.4 to 11.3 x 104/mul and from 42.5 to 24.7 IU/mul, respectively (fig. 3).