case_images: PMC4198115_01
case_images: PMC4198115_02
case_images: A) Pedigree of the NCL family. Black symbols refer to affected individuals.. Half-black symbols into third and fourth generation individuals symbols (III:6, III:7, IV:3) represents the MFSD8 c.1219T>C and c.1361T>C mutations at heterozygous state. B) Brain magnetic resonance imaging (T2-FLAIR image, axial section) of patient (P3) showing mild cerebral atrophy.
case_images: pone.0109576.g001.jpg
case_images: PMC4198115_02_pone.0109576.g001.jpg
case_images: pone-0109576-g001
case_images: MRI brain showed diffuse cerebral and cerebellar atrophy with normal thalamus ( Figure 1B ).
case_images: PMC4198115_03