case_images: PMC10413872_01
case_images: Clinical presentation of a 7-year-old American short hair cat showing signs of Horner's syndrome and laryngeal paralysis. Pharmacological testing with topical 1% phenylephrine (A, B). The left eye of a cat (red rectangle) showed miosis, protrusion of the third eyelid, ptosis, and enophthalmos consistent with Horner's syndrome (A). After topical administration of 1% phenylephrine to the left eye, clinical signs resolved within 20 min (B). Laryngoscopy images (C, D) showed the right and left arytenoid cartilage movement during inspiration. It confirmed the left-sided laryngeal paralysis.
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case_images: F1
case_images: A topical 1% phenylephrine test was performed for neurolocalization, and the related clinical signs resolved within 20 min after application (Figures 1A, B). Abnormal movements of the larynx consistent with left laryngeal paralysis were confirmed (Figures 1C, D) during the examination.
case_images: Computed tomography images of a 7-year-old American short hair cat with left-sided middle ear adenocarcinoma. Pre-contrast (A, C, E) and post-contrast (B, D, F) images of soft tissue mass around the tympanic bulla at each level. On transverse tympanic bulla level (A, B), bilateral tympanic bulla was filled with soft tissue density material. The left-sided bulla was expanded, and osteolysis (yellow arrow) was marked (A, C, E). The ventral margin of the bulla was disrupted, and a contrast-enhancing mass (orange arrow) around the tympanic bulla was noted (B, D, F). On the sagittal view (C-F), the tympano-occipital fissure (green arrow) (C, D) and the hypoglossal canal (red arrow) (E, F) were occupied with soft tissue mass.
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case_images: F2
case_images: CT i3D, Woorien, Seoul, South Korea) images of the head and neck were obtained (Figure 2). CT examination demonstrated hyper-attenuating materials within the bilateral tympanic cavity.
case_images: Histopathology of adenocarcinoma in the left tympanic bulla of a 7-year-old American shorthair cat. Microscopically, the mass was made up of glandular and solid pattern proliferation of polygonal to columnar epithelial cells. Neoplastic cells had abundant eosinophilic granular cytoplasm, and some cells had varying degrees of vacuolated cytoplasm. The nuclei of these cells were round to oval in shape and had one or two prominent nucleoli. These cells were moderately pleomorphic, and no mitotic figures were shown.
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case_images: F3
case_images: The mass was diagnosed as a low-grade adenocarcinoma with mild inflammatory cells (Figure 3).