case_images: PMC6120276_01
case_images: Necrotic lesions on the distal phalanges.
case_images: CRIHEM2018-1980749.001.jpg
case_images: PMC6120276_01_CRIHEM2018-1980749.001.jpg
case_images: fig1
case_images: Physical examination at admission highlighted necrotic lesions on the distal phalanges of both hands (except the thumbs) (Figure 1), enlarged lymph nodes in right axillary (3 cm), and right supraclavicular gaps (4 cm).
case_images: Resolution of necrotic lesions after 3 cycles of ABVD protocol (3 months from the HL diagnosis). Amputation of three phalanges was required.
case_images: CRIHEM2018-1980749.002.jpg
case_images: PMC6120276_01_CRIHEM2018-1980749.002.jpg
case_images: fig2
case_images: After surgery, a delay for healing due to acrosyndrome was not observed (Figure 2).
case_images: Lymph node biopsy sample. (a) Typical morphology of Reed-Sternberg cells, surrounded by a background of reactive inflammation, nodular sclerosis pattern (HE stain x40). Immunohistochemistry staining of the Reed-Sternberg population showed expression of (b) CD15 and (c) CD30. (d) CD20 expression was negative.
case_images: CRIHEM2018-1980749.003.jpg
case_images: PMC6120276_01_CRIHEM2018-1980749.003.jpg
case_images: fig3
case_images: Biopsy of axillary nodes demonstrated nodular sclerosis classical Hodgkin's lymphoma (HL) (Figure 3).