case_images: PMC11708175_01
case_images: Endoscopic findings and Pedigree chart of Family 1. a-c Endoscopic findings of the proband (II-1). A complete colonoscopy revealed more than 500 adenomatous polyps in the entire large intestine (a) and an additional EGD detected fundic gland polyposis (b) in the stomach and several non-ampullary duodenal adenoma (c). d Pedigree chart of Family 1
case_images: 13053_2024_297_Fig1_HTML.jpg
case_images: PMC11708175_01_13053_2024_297_Fig1_HTML.jpg
case_images: Fig1
case_images: A complete colonoscopy revealed more than 500 adenomatous polyps throughout the large intestine, and additional oesophagogastroduodenoscopy (EGD) detected fundic gland polyposis in the stomach and several non-ampullary duodenal adenomas (Fig. 1a-c). As shown in her family pedigree, she had no family history of colonic polyposis or colorectal cancer, despite the typical features of FAP (Fig. 1d).
case_images: PMC11708175_02
case_images: Endoscopic findings and Pedigree chart of Family 2. a-c Endoscopic findings of the proband (II-1). The patient underwent complete colonoscopy and around 50 adenomatous polyps were found in the entire large intestine (a). Additionally, fundic gland polyposis in the stomach (b) and several non-ampullary adenomas in the duodenum (c) were detected by EGD. d Pedigree chart of Family 2
case_images: 13053_2024_297_Fig2_HTML.jpg
case_images: PMC11708175_02_13053_2024_297_Fig2_HTML.jpg
case_images: Fig2
case_images: The patient underwent complete colonoscopy, and approximately 50 adenomatous polyps were found throughout the large intestine (Fig. 2a). Additionally, fundic gland polyposis in the stomach and several non-ampullary adenomas in the duodenum were detected on EGD (Fig. 2b-c). He appeared to have FAP based on his clinical phenotype, but had no family members with FAP phenotypes (Fig. 2d).