case_images: PMC4763580_01
case_images: (a and b) Multiple non healing ulcers over the shin
case_images: IDOJ-7-43-g001.jpg
case_images: PMC4763580_01_IDOJ-7-43-g001.jpg
case_images: F1
case_images: Three similar ulcers [Figure 1a and b] appeared on the shin over the next one month.
case_images: (a-c) Hyperplastic, sclerotic epidermis and a dense superficial and deep dermal infiltrate of lymphocyte and plasma cells concentrated around the blood vessels and sweat glands with several granulomas arranged in a horizontal manner in mid and lower dermis. (H and E, x10, x40, x40)
case_images: IDOJ-7-43-g002.jpg
case_images: PMC4763580_01_IDOJ-7-43-g002.jpg
case_images: F2
case_images: Skin biopsy from the edge of the ulcer revealed a hyperplastic, sclerotic epidermis and a dense superficial and deep dermal infiltrate of lymphocyte and plasma cells concentrated around the blood vessels and sweat glands [Figure 2a-c].
case_images: (a and b) Complete healing and softening of skin after treatment with thalidomide
case_images: IDOJ-7-43-g003.jpg
case_images: PMC4763580_01_IDOJ-7-43-g003.jpg
case_images: F3
case_images: Pain reduced dramatically within 2 weeks and the ulcers healed completely after 4 weeks [Figures 3a and b].