case_images: PMC11130422_01
case_images: Timeline. Chemotherapy and ICI consisting of carboplatin AUC 6, paclitaxel 200 mg/m2, and pembrolizumab 200 mg IV every 3 weeks. ICI, immune checkpoint inhibitor.
case_images: fimmu-15-1393901-g001.jpg
case_images: PMC11130422_01_fimmu-15-1393901-g001.jpg
case_images: f1
case_images: He had no history of chronic kidney disease, high blood pressure, urological disease, and gross hematuria ( Figure 1 ).
case_images: The patient's kidney biopsy shown by light microscopy: Glomeruli showing endocapillary hypercellularity (solid arrow, green), cellular crescent (hollow arrow, orange), and fibrinoid necrosis (asterisk, blue), x40 magnification, Masson's trichrome stain (A) and Jones' silver stain (B). Interstitium showing mild to moderate inflammation, edema, and diffuse acute tubular injury (C), x10 magnification, Masson's trichrome stain. (D) Immunofluorescence showed IgA mesangial staining without other significant deposit.
case_images: fimmu-15-1393901-g002.jpg
case_images: PMC11130422_01_fimmu-15-1393901-g002.jpg
case_images: f2
case_images: The kidney biopsy, performed 7 days after the admission and the beginning of oral corticosteroid, contained 16 glomeruli ( Figure 2 ).