case_images: PMC10847797_01
case_images: CT of the chest (bases) shows diffuse interstitial opacities. Interstitium is thickened and mildly irregular, more prominent in the dependent regions (1a). Periodic acid-Schiff stain (without and with diastase) confirms glycogen within interstitial mesenchymal cells (1b, 1c, respectively). Interstitial glycogenosis involves more than 30 % of the alveolar septa.
case_images: gr1c.jpg
case_images: PMC10847797_01_gr1c.jpg
case_images: fig1
case_images: CT scan of the chest was notable for diffuse bilateral interstitial opacities most prominent near the lung bases, with thickened interstitium and mild lymphangiectasia (Fig. 1).
case_images: CT of the lung bases shows low lung volumes with diffuse interstitial thickening. Right hemidiaphragm is elevated (2a). Periodic acid-Schiff stain (without and with diastase) confirms glycogen within interstitial mesenchymal cells (2b, 2c, respectively). In some biopsy profiles it involves 60-70 % of the area. In others, where the alveolar simplification and enlargement are more prominent, PIG involves 20-30 % of the area.
case_images: gr2c.jpg
case_images: PMC10847797_02_gr2c.jpg
case_images: fig2
case_images: Tissue exam of right lung biopsy described alveolar growth abnormality with periodic acid-Schiff stains demonstrated abundant non-membrane bound, monoparticulate glycogen within mesenchymal cells estimated to involve more than 30 % of the area, as well as areas of alveolar simplification (Fig. 2b, c).
case_images: PMC10847797_02
case_images: CT of the lung bases shows low lung volumes with diffuse interstitial thickening. Right hemidiaphragm is elevated (2a). Periodic acid-Schiff stain (without and with diastase) confirms glycogen within interstitial mesenchymal cells (2b, 2c, respectively). In some biopsy profiles it involves 60-70 % of the area. In others, where the alveolar simplification and enlargement are more prominent, PIG involves 20-30 % of the area.
case_images: gr2c.jpg
case_images: PMC10847797_02_gr2c.jpg
case_images: fig2
case_images: Tissue exam of right lung biopsy described alveolar growth abnormality with periodic acid-Schiff stains demonstrated abundant non-membrane bound, monoparticulate glycogen within mesenchymal cells estimated to involve more than 30 % of the area, as well as areas of alveolar simplification (Fig. 2b, c).