case_images: PMC6465719_01
case_images: Immunofluorescence shows 2+ linear stating along the glomerular basement membrane with antibodies against IgG (a) and kappa (b). All other stains including lambda (c) and albumin (d) were negative. IgG1 subclass shows 2+ linear staining of glomerular basement membrane (e). Staining for IgG subclasses IgG2, IgG3, and IgG4 was negative (not shown).
case_images: cnd-0009-0008-g01.jpg
case_images: PMC6465719_01_cnd-0009-0008-g01.jpg
case_images: F1
case_images: Kidney biopsy revealed linear staining along the GBMs by monotypic IgG1-kappa (Fig. 1) with numerous red blood cell casts (Fig. 2), interstitial fibrosis, tubular atrophy, moderate arteriosclerosis, and moderate arteriolar hyalinosis of moderate chronicity.
case_images: Electron microscopic examination of glomerulus reveals widespread effacement of the foot processes (black arrows) and absence of any immune complex electron dense deposits.
case_images: cnd-0009-0008-g03.jpg
case_images: PMC6465719_01_cnd-0009-0008-g03.jpg
case_images: F3
case_images: Electron microscopic examination of the glomerulus (Fig. 3) revealed widespread effacement of the foot processes and absence of any immune complex electron dense deposits.