case_images: PMC10989740_01
case_images: HE stained slides from (A-D) show: (A) squamous epithelium with no Pagetoid changes, while the dermal tumor exhibits a vaguely glandular structure (x10). (B) Shows infiltrative tumor cells forming irregular nests with stromal inflammatory reaction and (C) with geographic necrosis (x20). (D) Demonstrates vesicular nuclei with aberrant mitotic figures (x40).
case_images: pore-30-1611376-g001.jpg
case_images: PMC10989740_01_pore-30-1611376-g001.jpg
case_images: F1
case_images: The positive IHC staining for CK7, GATA3 and ER with high Ki67 labeling index is illustrated as below. Other stains are not shown.
case_images: pore-30-1611376-g002.jpg
case_images: PMC10989740_01_pore-30-1611376-g002.jpg
case_images: F2
case_images: IHC staining for CK7, GATA3, and ER shows strong positivity for CK7, GATA3, and ER with proliferation index by Ki67 over 90% (Figure 2).