case_images: PMC4578063_01
case_images: The CT scan of the thorax at aortic arch level showed a 4x3x3 cm-sized, well-defined mass in the posterior mediastinum. The mass showed high density with good contrast enhancement (arrow).
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case_images: The computed tomographic (CT) scan of the thorax, obtained after the injection of contrast material, showed a 4x3x3cm-sized, well-defined high density posterior mediastinal mass with a suspicious finding of rib destruction (Figure 1).
case_images: MRI imaging of the thoracic spine revealed an ovoid mass in the posterior mediastinum at T4-5 level with low signal intensity in T1-weighted image which is well enhanced after injection of contrast media. Epidural space invasion by the tumor was suspected (arrow).
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case_images: MRI imaging of the thoracic spine revealed a round mass in the posterior mediastinum at T4-5 level with low-signal intensity in T1-weighted image which was well enhanced and with suspicious epidural space-nvasion (Figure 2).
case_images: Histologic section of the tumor revealed exuberant mesenchymal proliferation which was intricately composed of mature adipocytes, opened or closed capillaries and smooth muscle fibers (H & E, x100).
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case_images: Histologically, the tissue was characterized by mesenchymal cell proliferation, intricately composed of mature fat, capillaries and smooth muscle fibers (Figure 3).
case_images: (A) The smooth muscle component showed scattered bundles of slender spindle cells with eosinophilic fibrillary cytoplasms and cigar-shaped nuclei (H & E, x200). (B) The smooth muscle fibers were immunohistochemically positive for smooth muscle actin (Avidin-biodin peroxidase, x200).
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case_images: In immunohistochemical staining to identify the different components of angiomyolipoma, smooth muscle actin was positive for smooth muscle component (Figure 4A, 4B), CD34 (Figure 5) and factor-VIII for vascular component were positive and S-100 was positive for fat component.
case_images: Immunostaining for CD34 antigen revealed many CD34-reactive capillaries intermingled with mature adipocytes (ABC method, x100).
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case_images: In immunohistochemical staining to identify the different components of angiomyolipoma, smooth muscle actin was positive for smooth muscle component (Figure 4A, 4B), CD34 (Figure 5) and factor-VIII for vascular component were positive and S-100 was positive for fat component.