case_images: PMC3383684_01
case_images: CT of Case 1, before (left; 02/08/'05) and after (right; 19/02/'09) the programmed chemotherapy.. 60 yrs old male with melena was introduced to our hospital. He had differentiated-type MGC with liver metastasis and local lymph metastases. He was classified as level 1 and was treated with S-1 plus CDDP combination for 6 cools. CR was confirmed radiologically.
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case_images: PMC3383684_01_pone.0038652.g004.jpg
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case_images: CDDP combination for four cycles. CR was confirmed radiologically (Figure 4) and endoscopically.
case_images: PMC3383684_02
case_images: Endoscopic features of Case 2.. PR was confirmed in Case 2 by endoscopic features before (left; 21/02/'07) and after (right; 29/06/'07) programmed chemotherapy.
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case_images: PMC3383684_02_pone.0038652.g005.jpg
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case_images: We therefore selected the next S-1 combination in accordance with the program for this patient, and he finally achieved partial response (PR) (Figure 5).
case_images: PMC3383684_03
case_images: The course of tumor markers in Case 3.. CEA and CA19-9 increased markedly when we stopped giving S-1, suggesting that S-1 was still effective to control the case.
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case_images: pone-0038652-g006
case_images: Her tumor markers increased markedly after we stopped S-1 treatment, suggesting that S-1 should have been effective for controlling this case (Figure 6).