case_images: PMC11659833_01
case_images: The characterization of case-1. A. Hearing curves before and after treatment for Case 1 (red and blue represent pre-treatment, pink and green represent post-treatment). B. Temporal bone CT findings for Case 1 show bilateral well-aerated mastoid air cells, clear bilateral tympanic cavity and mastoid antrum, and absence of apparent abnormal density lesions. Intact ossicular chain with no significant abnormalities in morphology and bone structure of auditory ossicles. No significant abnormalities observed in bony structures of bilateral inner ears.
case_images: ijmsv22p0179g001.jpg
case_images: PMC11659833_01_ijmsv22p0179g001.jpg
case_images: F1
case_images: Temporal bone CT imaging showed no structural abnormalities (Figure 1A-B).
case_images: PMC11659833_02
case_images: The characterization of case-2. A. Hearing curves before and after treatment for Case 2 (red and blue represent pre-treatment, pink and green represent post-treatment). B. Skull base MRI findings for Case 2 show bilateral patent external auditory canals, normal structures of middle ear tympanic cavity, mastoid sinuses, and mastoid antrum, intact bilateral ossicular chains, intact facial nerve canal structure, and normal structures of bilateral semicircular canals and cochlea in the inner ears.
case_images: ijmsv22p0179g002.jpg
case_images: PMC11659833_02_ijmsv22p0179g002.jpg
case_images: F2
case_images: Temporal bone MRI showed patent external auditory canals and normal middle ear structures (Figure 2A-B).
case_images: PMC11659833_03
case_images: The characterization of case-3. A. Hearing curves before and after treatment for Case 3 (red and blue represent pre-treatment, pink and green represent 4 weeks post-treatment, orange and brown represent 16 weeks post-treatment). B. PET-CT findings for Case 3 show bilateral patent mastoid antrums with no soft tissue density shadows, intact ossicular chains, and normal structures of bilateral cochlea.
case_images: ijmsv22p0179g003.jpg
case_images: PMC11659833_03_ijmsv22p0179g003.jpg
case_images: F3
case_images: PET-CT indicated enlargement and increased metabolic activity in bilateral submandibular, parotid, and lacrimal glands (Figure 3A-B), suggestive of IgG4-related systemic involvement.