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case_images: HRCT scan (March 2017).
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case_images: A 27-year-old male newly diagnosed with AD-HIES with mutation in STAT3 (c.1406A > G; c.1406A) was referred to a pulmonology clinic by the infectious disease clinic, because of incidental finding of large pulmonary infiltrates on his chest X-ray and computed tomography (CT) thorax as well as a cavity with a fungal ball-looking lesion (Figure 1).
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case_images: Graph showing voriconale treatment and correlation with C-reactive protein over
  time.
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case_images: BAL findings of S. pneumoniae and Achromobacter sp. Because of the high suspicion of pulmonary Aspergillosis, empiric Voriconazole treatment was prescribed for 11 months (Figure 2).
case_images: CT/PET image showing high FDG uptake in the right-sided infiltrate (May 2017).
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case_images: A control CT/positron emission tomography (PET) (Figure 3) 2 months later showed increased fluorodeoxyglucose (FDG) uptake at the level of the cavity; 8 months later a high-resolution computed tomography (HRCT) scan (Figure 4) showed further progression of cavitating lesion in the right upper lobe and new infiltrates caudally.
case_images: CT scan showing progressing infiltrate (Dec 2017).
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case_images: A control CT/positron emission tomography (PET) (Figure 3) 2 months later showed increased fluorodeoxyglucose (FDG) uptake at the level of the cavity; 8 months later a high-resolution computed tomography (HRCT) scan (Figure 4) showed further progression of cavitating lesion in the right upper lobe and new infiltrates caudally.
case_images: HRCT scan with partial resolution after treatment with oral glucocorticoids (May
  2018).
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case_images: A control CT thorax (Figure 5) after 1 month of this treatment regimen showed some regression of the infiltrate.
case_images: HRCT with further resolution of infiltrative changes (May 2019).
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case_images: A further follow-up CT thorax (Figure 6) 12 months later showed further regression of the infiltrate.
case_images: Graph showing Prednisolone treatment and correlation with leukocytes, neutrophils and
  lymphocytes over time.
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case_images: The Prednisolone treatment was subsequently stopped (Figure 7).