case_images: PMC9161546_01
case_images: (A) Case 1: rash on the inner side of the left thigh after 6 h of CBD use. The disappearance of the lesion on digital pressure is observed. (B) Case 2: confluent erythematous papules on the trunk and left arm after 8 days of CBD use. (C) Case 3: abdominal rash after 5 days of CBD use. The disappearance of the lesion on digital pressure is observed. (D) Case 3: evolution of rash to erythematous papules, surrounded by a hypochromic halo, on the lower limbs, after 10 days of CBD use.
case_images: fphar-13-881617-g001.jpg
case_images: PMC9161546_03_fphar-13-881617-g001.jpg
case_images: F1
case_images: A 34-year-old woman without comorbidities or medication use developed a rash on the abdomen after 5 days of CBD use (Figure 1C). On physical examination, monomorphic erythematous papular lesions with a hypochromic halo were observed on the trunk, back, buttocks, lower limbs, and upper limbs (Figure 1D), sparing the face and the palmoplantar region, and without mucosal lesions.
case_images: PMC9161546_02
case_images: (A) Case 1: rash on the inner side of the left thigh after 6 h of CBD use. The disappearance of the lesion on digital pressure is observed. (B) Case 2: confluent erythematous papules on the trunk and left arm after 8 days of CBD use. (C) Case 3: abdominal rash after 5 days of CBD use. The disappearance of the lesion on digital pressure is observed. (D) Case 3: evolution of rash to erythematous papules, surrounded by a hypochromic halo, on the lower limbs, after 10 days of CBD use.
case_images: fphar-13-881617-g001.jpg
case_images: PMC9161546_03_fphar-13-881617-g001.jpg
case_images: F1
case_images: A 34-year-old woman without comorbidities or medication use developed a rash on the abdomen after 5 days of CBD use (Figure 1C). On physical examination, monomorphic erythematous papular lesions with a hypochromic halo were observed on the trunk, back, buttocks, lower limbs, and upper limbs (Figure 1D), sparing the face and the palmoplantar region, and without mucosal lesions.
case_images: PMC9161546_03
case_images: (A) Case 1: rash on the inner side of the left thigh after 6 h of CBD use. The disappearance of the lesion on digital pressure is observed. (B) Case 2: confluent erythematous papules on the trunk and left arm after 8 days of CBD use. (C) Case 3: abdominal rash after 5 days of CBD use. The disappearance of the lesion on digital pressure is observed. (D) Case 3: evolution of rash to erythematous papules, surrounded by a hypochromic halo, on the lower limbs, after 10 days of CBD use.
case_images: fphar-13-881617-g001.jpg
case_images: PMC9161546_03_fphar-13-881617-g001.jpg
case_images: F1
case_images: A 34-year-old woman without comorbidities or medication use developed a rash on the abdomen after 5 days of CBD use (Figure 1C). On physical examination, monomorphic erythematous papular lesions with a hypochromic halo were observed on the trunk, back, buttocks, lower limbs, and upper limbs (Figure 1D), sparing the face and the palmoplantar region, and without mucosal lesions.
case_images: PMC9161546_04
case_images: (A) Case 4: erythematoedematous papules on the left upper limb after 9 days of CBD use. (B) Evolution of the lesions after 2 days, after medication discontinuation, and initiation of oral prednisone.
case_images: fphar-13-881617-g002.jpg
case_images: PMC9161546_04_fphar-13-881617-g002.jpg
case_images: F2
case_images: The physical examination showed monomorphic urticarial lesions (Figure 2A) that evolved after 2 days, with coalescence in the trunk, abdomen, and the upper and lower limbs (Figure 2B), even after discontinuing CBD in the period.