case_images: PMC9618642_01
case_images: PMC9618642_02
case_images: Brain imaging of subjects with PLPHP deficiency. MRI of subjects 2 (A-D) and 3 (E,F) at 4.5 and 2.5 years. (A,E) Sagittal T1 demonstrates thin corpus callosum. (B,F) Axial views show a patchy bilateral increase in T2 and (C,D,G,H) FLAIR signal in the deep white matter around the ventricles at bilateral frontal and bilateral peritrigonal regions. Both subjects have cerebral atrophy, most noted in subject 2, with a prominence of CSF spaces, particularly over frontal and sylvian regions bilaterally.
case_images: fneur-13-913652-g0001.jpg
case_images: PMC9618642_03_fneur-13-913652-g0001.jpg
case_images: F1
case_images: The CSF spaces and ventricles were enlarged, suggesting poor cerebral growth (Figures 1E-H).
case_images: PMC9618642_03
case_images: Brain imaging of subjects with PLPHP deficiency. MRI of subjects 2 (A-D) and 3 (E,F) at 4.5 and 2.5 years. (A,E) Sagittal T1 demonstrates thin corpus callosum. (B,F) Axial views show a patchy bilateral increase in T2 and (C,D,G,H) FLAIR signal in the deep white matter around the ventricles at bilateral frontal and bilateral peritrigonal regions. Both subjects have cerebral atrophy, most noted in subject 2, with a prominence of CSF spaces, particularly over frontal and sylvian regions bilaterally.
case_images: fneur-13-913652-g0001.jpg
case_images: PMC9618642_03_fneur-13-913652-g0001.jpg
case_images: F1
case_images: The CSF spaces and ventricles were enlarged, suggesting poor cerebral growth (Figures 1E-H).