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case_images: (A and B) Large infiltrative erythematous and swollen plaques with indistinct margins are seen on the face; (C) irregular erythematous plaques with scattered pinhead-sized pustules on the neck; (D) indistinct erythematous plaques with pinhead-sized pustules on some of the erythematous plaques are seen on the back, and some of the erythematous plaques are semi-annular in shape. (E and F) Diffuse erythematous desquamation with scattered pinhead-sized pustules overlying both hands and feet.
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case_images: Diffuse erythematous desquamation is observed on the hands and feet, with scattered pinpoint-sized pustules (Figure 1A-F).
case_images: (A) Mild edema of epidermal acanthocytes and a large number of eosinophils and a small number of neutrophil lymphocyte-dominated infiltrates around the hair follicle sebaceous gland in the dermis (HEx200x) (B) Eosinophil-formed abscess in the hair follicle and a small number of inflammatory cell infiltrates around the superficial dermal vessels (HEx400).
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case_images: Skin biopsy of the back erythema reveals mild edema of the epidermal keratinocytes, abundant eosinophilic infiltration with a small number of neutrophils and lymphocytes around the hair follicles and sebaceous glands in the dermis, pustule formation with eosinophilic infiltrates within the hair follicles, and a small amount of inflammatory cell infiltration around the superficial dermal blood vessels (Figure 2A and B).
case_images: (A-D) Largely disappeared skin lesions on the back of the face and neck.
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case_images: After ten days of treatment, the erythematous patches on the face, neck, and trunk mostly disappear, the pustules dry up, and a small number of adherent scales are observed (Figure 3A-D).