case_images: PMC9932368_01
case_images: Skin exanthema of various sites due to SDRIFE (A: Flexural forearm, B: Axillar area, C: Posterior neck, C: Inguinal region).
case_images: cureus-0015-00000033849-i01.jpg
case_images: PMC9932368_01_cureus-0015-00000033849-i01.jpg
case_images: FIG1
case_images: Dermatological examination of the posterior neck and the intertriginous area revealed many bilateral, symmetrical, well-demarcated blue-purple macules and plaques involving the axillary, flexures of the extremities, inguinal, and gluteal regions (Figure 1).
case_images: Perivascular inflammation
case_images: cureus-0015-00000033849-i02.jpg
case_images: PMC9932368_01_cureus-0015-00000033849-i02.jpg
case_images: FIG2
case_images: They revealed focal parakeratosis of the epidermis, significant spongiosis, irregular acanthosis, and perivascular moderately mixed inflammation in the dermis (Figure 2). Based on histology and clinical characteristics, SDRIFE was defined (Figures 2, 3).
case_images: Parakeratozis and spongiosis
case_images: cureus-0015-00000033849-i03.jpg
case_images: PMC9932368_01_cureus-0015-00000033849-i03.jpg
case_images: FIG3
case_images: Based on histology and clinical characteristics, SDRIFE was defined (Figures 2, 3).