case_images: PMC10646735_01
case_images: Gross appearance of atrophic right and left kidneys
case_images: ijp-18-480-g001.jpg
case_images: PMC10646735_01_ijp-18-480-g001.jpg
case_images: F1
case_images: On gross examination, each right and left nephrectomy specimen weighted 50 gram and measured 8x3x2 cm and 7x2x2 cm, respectively; consistent with atrophic appearance (Figure 1).
case_images: A. Negative for colloidal iron stain in transitional metaplasia of collecting ducts (X400). B. Negative Alcian blue stain in collecting ducts with transitional metaplasia, (X400). C. Negative PAS staining in the apical cytoplasm of metaplastic transitional ductal epithelium and PAS positive material in the lumen of some collecting ducts, (X400).
case_images: ijp-18-480-g002.jpg
case_images: PMC10646735_01_ijp-18-480-g002.jpg
case_images: F2
case_images: In Periodic acid Schiff (PAS) staining, negative staining in the apical cytoplasm of metaplastic transitional ductal epithelium and PAS positive material in the lumen of some collecting ducts were present (Figure 2). Colloidal iron and Alcian blue stains in metaplastic epithelium were negative (Figure 2).
case_images: Sections show renal papilla collecting ducts with transitional metaplasia (H&E stain, 100X, 400X). C, D. GATA3 nuclear immunohistochemical staining in transitional metaplasia of the collecting ducts (IHC stain 100X, 400X).
case_images: ijp-18-480-g003.jpg
case_images: PMC10646735_01_ijp-18-480-g003.jpg
case_images: F3
case_images: Immunohistochemical staining was performed to evaluate the transitional metaplasia using GATA3 nuclear staining (Figure 3).