case_images: PMC10832604_01
case_images: (a) Optos fundus photograph of the right eye showing a large refractory macular hole temporal to the optic nerve. (b) Zoomed-in Optos photograph of the posterior pole demonstrating the measurements of the large macular hole as well as the measurements of the optic nerve for comparison. (c) Swept-source OCT image taken across the diameter of the macular hole, demonstrating its extensive length (green line).
case_images: rjae013f1.jpg
case_images: PMC10832604_01_rjae013f1.jpg
case_images: f1
case_images: Fundus examination of the right eye revealed media opacities, a pale disc with peripapillary elevation due to subretinal fluid, a large macular hole measuring 15 sq mm (Fig 1a and b) with temporal subretinal fluid, and an area of large exudation in the periphery with a visible outline of the scleral buckle and peripheral laser scars amidst areas of fibrosis. Optical coherence tomography (OCT) confirmed the absence of the central retina (Fig 1c).
case_images: (a) Optos color fundus photograph of the right eye after amniotic membrane placement, with tissue remaining in place above the location of the previously demonstrated macular hole. (b) Zoomed-in Optos color photograph of the posterior pole demonstrating the graft in place. The green line indicates the location of the swept-source OCT in c. (c) Swept-source OCT shows the hole has been closed with amniotic membrane graft in place, and flat without subretinal fluid.
case_images: rjae013f2.jpg
case_images: PMC10832604_01_rjae013f2.jpg
case_images: f2
case_images: One year after amniotic membrane graft placement, the patient's BCVA improved to 20/200 in the right eye, with an intraocular pressure of 12 mmHg, and continued attachment of the amniotic membrane graft in the bed of the macular hole (Fig 2a and b). OCT confirmed integration of amniotic membrane graft with complete closure of macular hole (Fig 2c).