case_images: PMC11835195_01
case_images: Cutaneous histoplasmosis.. The figure shows hyperkeratotic lesions characteristic of psoriasiform histoplasmosis on the patient's buttocks. The lesions are firm papules, some with central umbilication and others with hyperkeratotic surfaces.. Clinical significance: These skin lesions are indicative of disseminated histoplasmosis and are key in differentiating it from other dermatological conditions.. Location and distribution: The lesions are distributed over the back, buttocks, trunk, limbs, face, scalp, axillae, and pubis.
case_images: cureus-0017-00000077668-i01.jpg
case_images: PMC11835195_01_cureus-0017-00000077668-i01.jpg
case_images: FIG1
case_images: Femoral head osteonecrosis.. X-ray showing the loss of sphericity of the femoral head and the loss of joint line regularity associated with subchondral condensation consistent with femoral head osteonecrosis.
case_images: cureus-0017-00000077668-i02.jpg
case_images: PMC11835195_01_cureus-0017-00000077668-i02.jpg
case_images: FIG2
case_images: Evolution of cutaneous rash after one month's treatment with itraconazole.. After one month of itraconazole, the molluscum-like papules and hyperkeratotic lesions over the back and buttocks started to resolve.
case_images: cureus-0017-00000077668-i03.jpg
case_images: PMC11835195_01_cureus-0017-00000077668-i03.jpg
case_images: FIG3
case_images: After one month of itraconazole, the diffuse rash noted on admission began to resolve with no recurrence after one year of follow-up (Figure 3).