case_images: PMC10637727_01
case_images: Ulcer lesions with a necrotic base and exophytic central crust on the face, affecting the frontal, temporal, infraorbital, parotideomasseteric, and left auricular regions (A and I) and left upper limb (E). During treatment with tecovirimat, a reduction in the diameter of the crusts in the frontal and temporal regions (B) and healing area with reduction of the crust were noted. Appearance of a new lesion with a necrotic center in the left upper limb (F). After approximately 45 days of tecovirimat treatment, the appearance of healing areas with a reduction in the size of the crusts on the face and scalp (C), complete healing of the lesions on the left upper limb and parotideomasseteric and left auricular region (D, G, H, K).
case_images: 1678-9849-rsbmt-56-e0228-2023-gf1.jpg
case_images: PMC10637727_01_1678-9849-rsbmt-56-e0228-2023-gf1.jpg
case_images: f1
case_images: He was hospitalized with ulcers and cornu cutaneum-like crusts on the face (Figure 1A, E, I ), and purulent discharge persisted in the anal canal. Finally, the lesions began to heal (Figure 1C, D, G, H, K), and the patient was discharged in March 2023.
case_images: PMC10637727_02
case_images: Ulcerated lesion with central necrosis and purulent border on the right cheek (A) and proximal phalanx on the upper lip of the third finger on the right hand (D). Abdominal radiography in orthostasis shows gaseous distension of the intestinal loops with Peer Review air-fluid level (B), and abdomen computed tomography shows distension of the colon, with heterogeneous content forming a level and irregular parietal thickening with reduced lumen transition between the sigmoid and the rectum (C and E).
case_images: 1678-9849-rsbmt-56-e0228-2023-gf2.jpg
case_images: PMC10637727_02_1678-9849-rsbmt-56-e0228-2023-gf2.jpg
case_images: f2
case_images: In October 2022, a 29-year-old man, MSM, with AIDS, presented to the ER with polymorphic bullous skin lesions on the upper limbs and dorsum (Figure 2A, D). Abdominal CT revealed marked distension of the colon, irregular and heterogeneous parietal thickening between the sigmoid and rectum, luminal reduction and densification of the local adipose planes, and enlargement of numerous lymph nodes in the mesorectal space (Figure 2B, C, E).