case_images: PMC11233050_01
case_images: (a and b) Large granulomatous ulcer extending over the shaft and root of penis up to pubic area (pre and posttreatment), (c) Gram stain showing plenty of pus cells and few encapsulated Gram-negative bacilli (x100), (d) Tissue smear stained with Giemsa stain showing bipolar condensation of Donovan bodies (x100)
case_images: IJSTD-45-64-g001.jpg
case_images: PMC11233050_01_IJSTD-45-64-g001.jpg
case_images: ijstd_9_24-f001
case_images: Local examination revealed two well-defined, irregular beefy-red ulcers which bled on touch with overlying granulation tissue; present over the root of penis, extending to involve the pubic region, scrotum, and prepuce [Figure 1a]. Gram-negative bacilli were visible [Figure 1c]. Giemsa stain showed pink ovoid bodies containing dark blue nuclei with bipolar condensation lying both within and outside of large monocytes suggestive of donovanosis [Figure 1d].
case_images: (a) Single skin-colored pedunculated nodule over the pubic area (genital molluscum), (b) Multiple shiny skin-colored papules with central umbilication noted over the forehead (extragenital molluscum), (c) HPE: Intraepithelial and dermal keratinocytes showing intracytoplasmic eosinophilic molluscum inclusion bodies (x10)
case_images: IJSTD-45-64-g002.jpg
case_images: PMC11233050_01_IJSTD-45-64-g002.jpg
case_images: ijstd_9_24-f002
case_images: Single skin-colored pedunculated nodule was noted over the pubic area [Figure 2a]. Multiple shiny skin-colored papules with central umbilication were noted over the forehead and scalp [Figure 2b]. Biopsy from the skin-colored pedunculated nodule over pubic area showed epidermis with short rete pegs and acanthosis, intraepithelial and dermal keratinocytes showing intracytoplasmic eosinophilic molluscum inclusion bodies along with focal aggregates of lymphocytes and macrophages, suggestive of molluscum contagiosum [Figure 2c].