case_images: PMC9834187_01
case_images: Plasma ammonia levels from July 2018 to September 2021 before and after treatment with carglumic acid (Carbaglu , CA)
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case_images: PMC9834187_01_MGG3-11-e2073-g002.jpg
case_images: mgg32073-fig-0001
case_images: Carglumic acid (Carbaglu , CA) was introduced (45 mg/kg/day) to treat persistent mild hyperammonemia (69 mumoL/L, normal value <50), (Figure 1).
case_images: Growth charts for height and weight (a and b) of patient from July 2018 to September 2021. Curves for 3rd, 25th, 50th, 75th and 97th are reported in each graph (growth charts reproduced from: Cacciari E, et al. Italian cross-sectional growth charts (2 to 20 yr). J Endocrinol invest. 2006; 29(7): 581-593)
case_images: MGG3-11-e2073-g003.jpg
case_images: PMC9834187_01_MGG3-11-e2073-g003.jpg
case_images: mgg32073-fig-0002
case_images: At the routine visits (aged 6 years 5 months; 6 years 8 months; 7 years 1 month and 7 years and 4 months), she was adhering well to therapy and her condition continued to improve (Figure 2a,b).