case_images: PMC10847898_01
case_images: Histological examination of liver biopsy. Histological examination of slides prepared with H&E staining and periodic-acid-Schiff (PAS) staining. Masson's trichrome shows liver tissue with a globally preserved lobular architecture and moderate to intense inflammatory infiltrate, with lymphocytes, plasmocytes, numerous polymorphonuclear neutrophils, and frequent epithelioid histiocytic cells with a vaguely granulomatous arrangement (thin black arrow), without necrosis.
case_images: cureus-0016-00000051840-i01.jpg
case_images: PMC10847898_01_cureus-0016-00000051840-i01.jpg
case_images: FIG1
case_images: Liver biopsy revealed moderate to intense polymorphic, portal and lobular inflammatory infiltrates, and frequent epithelioid histiocytic cells with a granulomatous arrangement, without necrosis (see Figure 1 and Figure 2).
case_images: Granulomatous arrangement in H&E staining of liver biopsy. H&E staining amplification (x40) showing the vaguely granulomatous arrangement (thick black arrow). Although typical fibrin-ring lipogranulomas were not identified, the findings are compatible with Q fever hepatitis.
case_images: cureus-0016-00000051840-i02.jpg
case_images: PMC10847898_01_cureus-0016-00000051840-i02.jpg
case_images: FIG2
case_images: Liver biopsy revealed moderate to intense polymorphic, portal and lobular inflammatory infiltrates, and frequent epithelioid histiocytic cells with a granulomatous arrangement, without necrosis (see Figure 1 and Figure 2).