case_images: PMC10947762_01
case_images: Flow cytometry showing CD20+, CD19+, CD5+, CD23-, CD10+ (weak), lambda restricted. (a) CD45 versus SSC, (b) CD20 versus SSC, (c) CD19 versus CD20, (d) CD5 versus CD23, (e) CD5 versus CD20, (f) Kappa versus lambda, (g) CD19 versus CD10
case_images: IJABMR-14-63-g001.jpg
case_images: PMC10947762_01_IJABMR-14-63-g001.jpg
case_images: ijabmr_406_23-f001
case_images: Negativity for nTdT and CD23 favored the possibility of MCL with aberrant CD10 expression [Figure 1].
case_images: Biopsy from chest wall swelling shows diffuse sheets of large atypical lymphoid cells with conspicuous nucleoli (H and E, x400), IHC: The neoplastic cells are strongly positive for CD20, CD5, Cyclin D1, CD10 with high Ki 67, and CD23 negative (IHC, x400)
case_images: IJABMR-14-63-g002.jpg
case_images: PMC10947762_01_IJABMR-14-63-g002.jpg
case_images: ijabmr_406_23-f002
case_images: TdT [Figure 2]. These findings were consistent with a diagnosis of a blastoid variant of mantle cells with CD10 aberrant expression.