case_images: PMC6505228_01
case_images: (a) Right chest breast mass, (b) chest X-ray, and (c) computed tomography of
  chest (prior to thoracentesis).
case_images: 10.1177_2324709619847230-fig1.jpg
case_images: PMC6505228_01_10.1177_2324709619847230-fig1.jpg
case_images: fig1-2324709619847230
case_images: The patient reported having a right chest wall/breast mass since childhood but noticed significant worsening for several months prior to being seen (Figure 1a). An admission chest X-ray was notable for complete opacification of the right lung compatible with a large pleural effusion (Figure 1b). Further workup with computed tomography scan of the chest revealed a 6 to 7 cm mass in the right breast with right axillary adenopathy, a large right pleural effusion, and a 7-mm soft tissue nodule at the left lung base (Figure 1c).
case_images: Core biopsy of the right breast mass. (a) Invasive ductal carcinoma, (b)
  estrogen receptor positive, and (c) GATA-3 antibody staining pattern: GATA-3
  antibody appears to have an essential role in controlling genes that are
  involved in differentiation and proliferation of breast cancer.
case_images: 10.1177_2324709619847230-fig2.jpg
case_images: PMC6505228_01_10.1177_2324709619847230-fig2.jpg
case_images: fig2-2324709619847230
case_images: The patient underwent an ultrasound-guided core biopsy of the right breast mass with pathology revealing invasive ductal carcinoma, grade 2, and positive for estrogen receptor (ER) 90%, progesterone receptor (PR) 1% to 5%, and human epidermal growth factor receptor 2 positive, equivocal by immunohistochemistry, and positive by FISH (fluorescence in situ hybridization; Figure 2a-c).