case_images: PMC10046802_01
case_images: PMC10046802_02
case_images: Timing of major events in both kidney transplant recipients. (A) Recipient of the right kidney. (B) Recipient of the left kidney.
case_images: fmed-10-1142611-g001.jpg
case_images: PMC10046802_02_fmed-10-1142611-g001.jpg
case_images: fig1
case_images: The timing of most important events for both recipients is presented in Figure 1.
case_images: Histopathological findings in the recipient of the right kidney. (A) Adenocarcinoma in the surveillance biopsy of the graft [hematoxylin-eosin (H&E)]. (B) Adenocarcinoma in the surveillance biopsy of the graft - closer view (H&E). (C) Adenocarcinoma in the surveillance biopsy of the graft expressing cytokeratin 7 (immunohistochemical staining). (D) Adenocarcinoma in the surveillance biopsy of the graft expressing mucin-1 protein (immunohistochemical staining).
case_images: fmed-10-1142611-g002.jpg
case_images: PMC10046802_02_fmed-10-1142611-g002.jpg
case_images: fig2
case_images: Immunohistochemical findings (positive immunohistochemical staining for cytokeratin 19 and 7 and mucin-1 protein) suggested a pancreatic origin of the tumor (Figure 2).
case_images: Ultrasound of the growing formation (arrow) in the kidney graft seen in the left kidney transplant recipient. An aspiration needle biopsy showed poorly differentiated cells of metastatic adenocarcinoma.
case_images: fmed-10-1142611-g003.jpg
case_images: PMC10046802_02_fmed-10-1142611-g003.jpg
case_images: fig3
case_images: In summer and fall 2017, serial ultrasound examinations of the graft showed growing complex formation in the lower pole of the kidney (Figure 3).
case_images: Pathological findings in the recipient of the left kidney. (A) Macroscopic view of the adenocarcinoma (arrow). (B) Adenocarcinoma by light microscopy (H&E).
case_images: fmed-10-1142611-g004.jpg
case_images: PMC10046802_02_fmed-10-1142611-g004.jpg
case_images: fig4
case_images: Examination of the explanted kidney revealed an adenocarcinoma with identical immunohistochemical features as in the first recipient, suggesting a pancreatic origin of the tumor (Figure 4).