case_images: PMC10898913_01
case_images: Evolution of the patient's MRI over different time periods. Left: Abdominal MRI at the beginning of immunomodulatory therapy (30 December 2016) - showing post-right nephrectomy and two small solid nodules with neoplastic appearance found in the right renal fossa. Right: Abdominal MRI after 50 cycles of immunomodulatory therapy (8 July 2022) - showing a complete response with no secondary neoplastic involvement observed in the abdomen and pelvis.
case_images: can-17-1643fig1.jpg
case_images: PMC10898913_01_can-17-1643fig1.jpg
case_images: figure1
case_images: Extension studies were conducted, showing multiple bone metastases in the thoracic vertebrae, knee and right hip, as well as metastatic compromise of the lung, mediastinum, and retroperitoneal right renal fossa (Figures 1 and 2). Notably, this was the first time in which imaging did not reveal any lesions since the initial documentation of metastatic disease (Figures 1 and 2).
case_images: Evolution of the patient's computed tomography scans over different time periods. Left: CT scan at the beginning of immunomodulatory therapy (30 December 2016) - showing multiple solid pulmonary nodules (8-13 mm) predominantly in the peripheral left mid upper and lower lobes and left hilar adenopathies (15-17 mm). Right: CT scan (8 July 2022) - showing complete response of thoracic lesions after 50 cycles of immunomodulatory therapy.
case_images: can-17-1643fig2.jpg
case_images: PMC10898913_01_can-17-1643fig2.jpg
case_images: figure2
case_images: Extension studies were conducted, showing multiple bone metastases in the thoracic vertebrae, knee and right hip, as well as metastatic compromise of the lung, mediastinum, and retroperitoneal right renal fossa (Figures 1 and 2). Notably, this was the first time in which imaging did not reveal any lesions since the initial documentation of metastatic disease (Figures 1 and 2).
case_images: Chronological overview of key patient treatments and outcomes.
case_images: can-17-1643fig3.jpg
case_images: PMC10898913_01_can-17-1643fig3.jpg
case_images: figure3
case_images: To date, the patient has received 66 cycles of immunotherapy without experiencing adverse effects and has sustained complete remission (Figure 3).