case_images: PMC11804941_01
case_images: During the initial visit, the patient presented with extensive purulent deposits on the tooth surfaces, accompanied by multiple residual roots. In addition, significant ulceration was noted on the mucosa of the cheeks and upper palate.
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case_images: PMC11804941_01_fmed-11-1458606-g001.jpg
case_images: fig1
case_images: Three months ago, the patient developed ulcers on the maxillary gums and mucosa, accompanied by local purulent plaques (Figure 1).
case_images: A plain computed tomography scan of the maxillofacial region indicated local bone destruction with surrounding soft tissue swelling on the right upper palate.
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case_images: PMC11804941_01_fmed-11-1458606-g002.jpg
case_images: fig2
case_images: A plain computed tomography scan of the maxillofacial region indicated local bone destruction with surrounding soft tissue swelling on the right upper palate, prompting clinical correlation and biopsy to exclude neoplasms (Figure 2).
case_images: The tissue biopsy results revealed diffuse proliferation of atypical lymphocytes of varying sizes. Immunohistochemical results indicated PAX-5 (cells+), Mum-1 (plasma cells+), and Ki-67 (ulcer area+, 20%).
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case_images: fig3
case_images: Immunohistochemical results (Figures 3, 4) indicated CD79a (B cells+), CD20 (B cells+), Mum-1 (plasma cells+), Ki-67 (ulcer area+, 20%), EBER (+), PAX-5 (cells+), C-myc (<5%), and CD30 (+), suggesting EBV-positive mucocutaneous ulcers.
case_images: Immunohistochemical results indicated CD20 (B cells+), CD30 (+), C-myc (<5%), and EBER (+).
case_images: fmed-11-1458606-g004.jpg
case_images: PMC11804941_01_fmed-11-1458606-g004.jpg
case_images: fig4
case_images: Immunohistochemical results (Figures 3, 4) indicated CD79a (B cells+), CD20 (B cells+), Mum-1 (plasma cells+), Ki-67 (ulcer area+, 20%), EBER (+), PAX-5 (cells+), C-myc (<5%), and CD30 (+), suggesting EBV-positive mucocutaneous ulcers.