case_images: PMC10612521_01
case_images: Imaging studies before and after ICI therapy. (A and B) A 4.83x3.73 cm hypervascular mass at liver S5. The mass had invaded her gallbladder and encased the right hepatic artery. (A) Arterial phase, (B) delayed phase; (C and D) after nivolumab, the tumor decreased from 4.83 cm to 3.21 cm (>30% reduction). The major vessels including right hepatic artery were spared from tumor invasion. (C) Arterial phase, (D) delayed phase.
case_images: JHC-10-1873-g0001.jpg
case_images: PMC10612521_01_JHC-10-1873-g0001.jpg
case_images: f0001
case_images: The mass had invaded her gallbladder and encased the right hepatic artery (Figure 1A and B). The major vessels including right hepatic artery were spared from tumor invasion (Figure 1C and D).
case_images: PMC10612521_02
case_images: Imaging studies before and after ICI therapy. (A) A 10.32x7.15 cm hypervascular tumor was found at S6 of liver. (B and C) Recurrent HCCs were found at S6 (1.29 cm) (B) and S1 (2.82 cm) (C) of liver. (D) The tumor at S1 demonstrated partial response after 8 cycles (from 2.82 cm to 1.94 cm). However, it enlarged at cycle 13 (from 1.94 cm to 2.43 cm).
case_images: JHC-10-1873-g0002.jpg
case_images: PMC10612521_02_JHC-10-1873-g0002.jpg
case_images: f0002
case_images: S6 of liver (Figure 2A). She received laparoscopic hepatectomy to remove the tumor. One year after the operation, CT found recurrent HCCs at S1 (2.82 cm) and S6 (1.29 cm) of liver (Figure 2B and C). However, the tumor was found to enlarge at cycle 13 (from 1.94 cm to 2.43 cm) (Figure 2D).
case_images: PMC10612521_03
case_images: Imaging studies before and after ICI therapy. (A and B) A huge conglomerate tumor (18x14x10 cm) at the right inferior lobe of liver with obliteration of right portal vein. (C and D) The tumor reduced to 9.44x5.66 cm in size after 17 cycles of Atezo/Bev, and the right portal vein tumor thrombus (PVTT) also regressed.
case_images: JHC-10-1873-g0003.jpg
case_images: PMC10612521_03_JHC-10-1873-g0003.jpg
case_images: f0003
case_images: CT furthered disclosed a huge conglomerate tumor (18 x 14 x 10 cm) at the right inferior lobe of liver with obliteration of right portal vein (Figure 3A and B). The tumor remained stationary in size after 17 cycles of Atezo/Bev, and the right PVTT also regressed (Figure 3C and D).