case_images: PMC10798064_01
case_images: Magnetic resonance enterography revealed small bowel wall thickening (arrow).
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case_images: Magnetic resonance enterography revealed small bowel wall thickening of 15 mm x 2 mm (Figure 1).
case_images: (A) Intraoperative views showing the tumor (arrow) with mesenteric lymphadenopathy (asterisk). (B) Gross examination revealed a polypoid mass within the small intestine wall. (C) On the cut section, the mass had a tan-white lobulated appearance.
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case_images: A wide resection of the mass was then performed (Figure 2A). On the cut section, the mass displayed a lobulated appearance with a tan-white color (Figure 2B and C).
case_images: (A) Microscopic examination revealed an infiltrative proliferation centered in the submucosa of the ileum (H&E stain, x40). (B) The proliferation displayed a nested pattern of growth (H&E stain, x100). (C) The tumor was composed of uniform epithelioid and spindle cells with variable amounts of eosinophilic cytoplasm. The nuclei were vesicular with inconspicuous nucleoli and mitotic figures. (H&E stain, x400).. Abbreviation: H&E, hematoxylin and eosin.
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case_images: Three mesenteric lymph nodes were found to be free from malignancy (Figure 3).
case_images: (A) Diffuse and strong staining with S100. (B) Diffuse and strong staining with SOX10. (C) Staining with HMB45 was negative. (D) The tumor cells did not express Melan A.
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case_images: CD117, DOG1, cytokeratin, CD34, smooth muscle actin (SMA), desmin, chromogranin, and CD56 showed all negative results (Figure 4).