case_images: PMC5020471_01
case_images: Panel a, b, c: HRCT scan images demonstrating atypical paraseptal emphysema; Panel d: flow-volume loops showing normal values
case_images: 40248_2016_69_Fig1_HTML.jpg
case_images: PMC5020471_01_40248_2016_69_Fig1_HTML.jpg
case_images: Fig1
case_images: In detail, the CT scan allowed to report in many sections a single chaplet layer of bubbles with thin walls formed by interlobular septa typical for PE (Fig. 1,a). As opposite, it differed from typical PE because lesions were not entirely peripheral and interested mainly the lobules localized at the center of the lung (Fig 1,b). Moreover, chest alterations were consistent neither with CLE, since they mainly affected lower lobes instead of the expected upper ones (Fig. 1,c), nor with PLE because of the presence of cyst-like lesions. The global spirometry showed normal lung function together with a slightly reduced diffusing capacity (DLCO) (Fig. 1,d).