case_images: PMC8010692_01
case_images: (A) Magnetic resonance imaging revealing a soft tissue mass in the left scrotum. (B) Surgical piece of the left orchiectomy presenting a 9.5 x 5.0 x 4.5 cm3 paratesticular tumor. (C) Histopathological section (hematoxylin and eosin staining). (D) Immunohistochemistry results showing the expression of Desmin. (E) Immunohistochemistry results showing the expression of MyoD1. (F) Immunohistochemistry results showing the expression of Myogenin.
case_images: fonc-11-629878-g001.jpg
case_images: PMC8010692_01_fonc-11-629878-g001.jpg
case_images: f1
case_images: On the other hand, magnetic resonance imaging (MRI) showed that the soft tissue mass in the left scrotum was closely associated with the epididymis and had gradual enhancement after contrast suggesting that the lesion might be arising from mesenchymal tissues (Figure 1A). During the operation, a pear-like lesion could be seen on the cauda epididymis with a complete outer membrane (scrotal sheath) and a diameter of 9.5 x 5.0 x 4.5 cm (Figure 1B). The postoperative pathological examination confirmed eRMS (Figure 1C) and a negative surgical margin. In addition, IHC analysis revealed the expression of Desmin, MyoD1 and Myogenin in the excised tissue samples (Figures 1D-F).
case_images: PMC8010692_02
case_images: (A) Recurrent tumors in the left inguinal region for a duration of 1 month. (B) Magnetic resonance imaging revealing presence of a soft tissue mass above the left groin and pelvis. (C) Surgical biopsy of the recurrent tumors from the left inguinal and pelvic region (D) Histopathological section (hematoxylin and eosin staining). (E) Immunohistochemistry results showing the expression of Desmin. (F) Immunohistochemistry results showing the expression of MyoD1.
case_images: fonc-11-629878-g002.jpg
case_images: PMC8010692_02_fonc-11-629878-g002.jpg
case_images: f2
case_images: This mass was hard and immobile, growing into the pelvic cavity (Figure 2A), but superficial lymph nodes were normal in size. In addition, chest, abdominal and pelvis CT and MRI scans showed an irregular lesion above the left groin and pelvis (Figure 2B), indicating tumor recurrence and metastasis. Postoperative pathologic examinations showed that the gross specimen had no obvious capsule and had a pale profile with a fish-flesh appearance (Figure 2C). In addition, the examination revealed that the recurrent tumor was eRMS and resection margins were negative (Figure 2D). The immunostaining results showed the expression of Desmin and MyoD1 in the tumor cells (Figures 2E, F).