case_images: PMC9082725_01
case_images: Consumptive coagulopathy trend for patient 1 during hospitalisation. IVIg, intravenous immunoglobulin.
case_images: bmjno-2022-000270f01.jpg
case_images: PMC9082725_01_bmjno-2022-000270f01.jpg
case_images: F1
case_images: The patient's coagulation parameters steadily improved over the course of 11 days on argatroban and a further two doses of 0.5 g/kg IVIg (figure 1).
case_images: PMC9082725_02
case_images: Axial slices of CT brain demonstrating (A) intraparenchymal haematoma within right temporal lobe extending into the occipital lobe with extra-axial haematoma adjacent to frontal, temporal and parietal lobes. (B, C) Axial CT venogram with images showing partial thrombosis of superior aspect of the right internal jugular vein.
case_images: bmjno-2022-000270f02.jpg
case_images: PMC9082725_02_bmjno-2022-000270f02.jpg
case_images: F2
case_images: CT brain demonstrated extensive right-sided temporal lobe haemorrhage with mass effect (figure 2).
case_images: Coagulopathy trend for patient 2 during hospitalisation. IVIg, intravenous immunoglobulin.
case_images: bmjno-2022-000270f03.jpg
case_images: PMC9082725_02_bmjno-2022-000270f03.jpg
case_images: F3
case_images: Initial pathology demonstrated evidence of a severe thrombocytopenia (platelet count of 26x109/L), markedly elevated D-dimer >20 mg/L and a low fibrinogen level at 0.9 g/L (figure 3). Significant platelet increment, rising fibrinogen and decreasing D-dimer levels were noted following IVIg (figure 3).
case_images: PMC9082725_03