case_images: PMC4719350_01
case_images: A seven month old infant presented with X-ray of left tibia showed an expansile osteolytic and poorly demarcated lesion involving the metaphyseo-diaphyseal region of left upper tibia with no periosteal reaction.
case_images: JOCR-5-37-g001.jpg
case_images: PMC4719350_01_JOCR-5-37-g001.jpg
case_images: F1
case_images: X-ray of left tibia showed an expansile osteolytic and poorly demarcated lesion involving the metaphyseo-diaphyseal region of left upper tibia (Fig 1).
case_images: MRI of left tibia showed relatively well delineated expansile metadiaphyseal intramedullary lesion in the proximal and mid tibia with marked cortical thinning and suspicion of cortical breach.
case_images: JOCR-5-37-g002.jpg
case_images: PMC4719350_01_JOCR-5-37-g002.jpg
case_images: F2
case_images: Surrounding periosteal thickening was seen with edematous changes (Fig 2).
case_images: Histology of the lesion showing inter anastomosing capillary sized vessels lined by polygonal cells. (H&E, 40X)
case_images: JOCR-5-37-g003.jpg
case_images: PMC4719350_01_JOCR-5-37-g003.jpg
case_images: F3
case_images: Microscopic examination of sections from bone showed a vascular neoplasm composed of interanastomosing capillary sized vessels(Fig 3).
case_images: Immunoistochemistry showing CD34 positivity by tumour cells(40X)
case_images: JOCR-5-37-g004.jpg
case_images: PMC4719350_01_JOCR-5-37-g004.jpg
case_images: F4
case_images: The tumor was immunoreactive for factor CD34 and vimentin (Fig 4).
case_images: Sequential Radiographs show progressive regression of the lesion. Radiographs (from left to right) 6 montinone year and two year follow tip
case_images: JOCR-5-37-g005.jpg
case_images: PMC4719350_01_JOCR-5-37-g005.jpg
case_images: F5
case_images: The lesion showed a dramatic response by spontaneous regression during this period (Fig 5) and by the end of 1 1/2 years the lesion almost healed (Fig. 5).