case_images: PMC9672085_01
case_images: X-ray of both knee joints indicated uneven bone density in bilateral femoral diaphysis, epiphysis, and proximal tibia, with multiple low-density sites and calcification.
case_images: fped-10-995340-g001.jpg
case_images: PMC9672085_01_fped-10-995340-g001.jpg
case_images: F1
case_images: Imaging examinations included bilateral knee x-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), and whole-body bone imaging (Figures 1-3).
case_images: Coronal (A) and sagittal (B) MRI images indicated that lump-shaped shadow with long T1 and T2 signal was observed in the bottom of the femurs and in the upper end of tibias on both sides, no abnormality was observed in the shape and signal of the medial and lateral meniscus. After 6 months follow-up, we could see that the lesion was smaller than before (C).
case_images: fped-10-995340-g002.jpg
case_images: PMC9672085_01_fped-10-995340-g002.jpg
case_images: F2
case_images: Imaging examinations included bilateral knee x-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), and whole-body bone imaging (Figures 1-3).
case_images: Whole-body bone imaging showed increased radiation in bone metabolism of bilateral lower femurs after intravenous 10 mCi of 99 mTc-MDP.
case_images: fped-10-995340-g003.jpg
case_images: PMC9672085_01_fped-10-995340-g003.jpg
case_images: F3
case_images: Imaging examinations included bilateral knee x-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI), and whole-body bone imaging (Figures 1-3).
case_images: The left side of the distal femoral bone cortex was changing slightly rough in the operation (A), and the postoperative pathology results were showed (B: HE, x200; C: positive D2-40, x100).
case_images: fped-10-995340-g004.jpg
case_images: PMC9672085_01_fped-10-995340-g004.jpg
case_images: F4
case_images: Postoperative pathology results showed positivity for CD31, SMA, Ki-67, CD34, FA-8, ERG, and D2-40, and negativity for NSE (Figure 4).