case_images: PMC5836235_01
case_images: Barium enema showing filling defects and a partial ileum stricture (arrows).
case_images: crg-0012-0063-g01.jpg
case_images: PMC5836235_01_crg-0012-0063-g01.jpg
case_images: F1
case_images: Barium enema showed filling defects of the ileum (Fig. 1).
case_images: Small-bowel CT demonstrating bowel thickening, distal bowel dilation, and "comb" sign (arrows).
case_images: crg-0012-0063-g02.jpg
case_images: PMC5836235_01_crg-0012-0063-g02.jpg
case_images: F2
case_images: CT (Fig. 2). Colonoscopy was performed and returned without ulcers or nodularities.
case_images: Surgical specimen showing ileum fibrosis and stenosis, and multiple cobblestone appearances (arrows).
case_images: crg-0012-0063-g03.jpg
case_images: PMC5836235_01_crg-0012-0063-g03.jpg
case_images: F3
case_images: The surgical specimen showed severe fibrosis and stenosis of 6 cm in length, the maximum depth of the lesion was 1.8 cm, additional to multiple cobblestone appearances (Fig. 3).
case_images: a Diffused lymphohistiocytic infiltration and well-formed granulomas were observed microscopically (HE x20) (arrows). b Periodic acid-Schiff staining revealed budding forms of histoplasma capsulatum within macrophages (HE x40) (arrows).
case_images: crg-0012-0063-g04.jpg
case_images: PMC5836235_01_crg-0012-0063-g04.jpg
case_images: F4
case_images: Hematoxylin and eosin staining and immunohistochemistry with periodic acid-Schiff revealed budding forms of histoplasma capsulatum within the macrophages (Fig. 4).