case_images: PMC7781713_01
case_images: CT scan showing lytic bone lesions.
case_images: CRIHEM2020-8823877.001.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.001.jpg
case_images: fig1
case_images: Bone survey and computed tomography scan (CT scan) findings were consistent with multiple lytic lesions in the vertebrae (Figure 1) and hepatosplenomegaly.
case_images: Plasma cells in bone marrow aspirate smear.
case_images: CRIHEM2020-8823877.002.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.002.jpg
case_images: fig2
case_images: Bone marrow biopsy showed >90% kappa-restricted plasma cells, which were CD 138 positive by immunohistochemistry (Figures 2 and 3).
case_images: Bone marrow CD 138 IHC stain.
case_images: CRIHEM2020-8823877.003.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.003.jpg
case_images: fig3
case_images: Bone marrow biopsy showed >90% kappa-restricted plasma cells, which were CD 138 positive by immunohistochemistry (Figures 2 and 3).
case_images: Circulating plasma cells in peripheral blood smear.
case_images: CRIHEM2020-8823877.004.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.004.jpg
case_images: fig4
case_images: Peripheral smear showed 55% plasma cells leading to the diagnosis of IgM pPCL (Figure 4).
case_images: Serum monoclonal proteins.
case_images: CRIHEM2020-8823877.005.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.005.jpg
case_images: fig5
case_images: IgM level decreased to 200 mg/dL, M protein to 0.2 gm/dL, and bone marrow plasma cells to 3%, with no peripheral plasma cells (Figures 5 and 6).
case_images: Ig M levels.
case_images: CRIHEM2020-8823877.006.jpg
case_images: PMC7781713_01_CRIHEM2020-8823877.006.jpg
case_images: fig6
case_images: IgM level decreased to 200 mg/dL, M protein to 0.2 gm/dL, and bone marrow plasma cells to 3%, with no peripheral plasma cells (Figures 5 and 6).