case_images: PMC9743192_01
case_images: Urticarial and palpable non-blanching purpuric rash compatible with mild mixed perivascular infiltration of lymphocytes and neutrophils in the superficial dermis, oedema of blood vessels endothelium, no vessels wall necrosis identified.
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case_images: PMC9743192_01_j_med-2022-0608-fig001.jpg
case_images: j_med-2022-0608_fig_001
case_images: On the initial physical examination, next to typical urticaria on the limbs and trunk, some palpable non-blanching purpuric papules were noticed on the thighs (Figure 1). Histopathologic findings revealed mild mixed perivascular infiltration of lymphocytes and neutrophils in the superficial dermis, a thin interstitial neutrophil infiltrate of the derma, oedema of the vascular endothelium, and vessel wall necrosis, but no signs of IgA vasculitis were found (Figure 1).
case_images: PMC9743192_02
case_images: A palpable non-blanching purpuric rash on the right thigh and a sore with necrosis signs on the right shin.
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case_images: PMC9743192_02_j_med-2022-0608-fig002.jpg
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case_images: On physical examination, a palpable non-blanching purpuric rash on all extremities (Figure 2) was evident with some small sores with necrosis on the right shin (Figure 2).
case_images: Small vessels oedema of endothelium with perivascular leukocytoclasis, erythrocytes extravasation with focal IgA deposition in the vessels.
case_images: j_med-2022-0608-fig003.jpg
case_images: PMC9743192_02_j_med-2022-0608-fig003.jpg
case_images: j_med-2022-0608_fig_003
case_images: IgA deposition in the vessels (Figure 3). IgA vasculitis (Henoch-Schonlein purpura) was diagnosed.