case_images: PMC5259930_01
case_images: Bronchial washing cytology shows bronchial epithelial cells and mixed acute and chronic inflammatory infiltrate, including numerous histiocytes. Most histiocytes were packed with many yeast-like organisms (Pap, x400) with inset showing oval to oblong in shape with central transverse septum (GMS, x1000)
case_images: JCytol-34-45-g001.jpg
case_images: PMC5259930_01_JCytol-34-45-g001.jpg
case_images: F1
case_images: Most histiocytes were packed with many yeast-like organisms measuring 3mm in diameter that stained dark brown on methenamine silver (GMS) stain [Figure 1]. The most characteristic feature was a central transverse septum that was transparent with Papanicolaou stain but highlighted by GMS stain [Figure 1].
case_images: Bronchoscopic biopsy shows diffuse histiocytic proliferation with organisms in submucosa. (H&E, x400)
case_images: JCytol-34-45-g002.jpg
case_images: PMC5259930_01_JCytol-34-45-g002.jpg
case_images: F2
case_images: In Hematoxylin and eosin (H and E)-stained sections, the organisms were seen as nonbudding round-to-oval spherules within the histiocytes in the submucosa of bronchi [Figure 2].