case_images: PMC10901989_01
case_images: Histopathological examination (scale bar 50 mum) of the surgical specimen from the lesion of left breast showed invasive ductal carcinoma grade 3 (A). Immunohistochemically, tumor cells were negative for estrogen receptor (B), progesterone receptor (C) and HER2 (D) and Ki67 score was 78% (E).
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case_images: PMC10901989_01_fonc-14-1340419-g001.jpg
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case_images: PgR (Allred score 0), HER2 (IHC score 0), and MIB1 (78%) ( Figures 1A-E ). Postoperative dose-dense doxorubicin plus cyclophosphamide (ddAC; doxorubicin 60 mg/m2 day1, cyclophosphamide 600 mg/m2 day1, 2-week cycle)x4 cycles followed by dose-dense paclitaxel (ddPTX; paclitaxel 175 mg/m2 day1, 2-week cycle)x4 cycles, then radiation to the residual breast, was planned for the adjuvant therapy.
case_images: Contrast-enhanced CT showed pancreatic enlargement and peri-pancreatic fluid (indicated by yellow arrows), meeting criteria for mild acute pancreatitis according to the revised Atlanta classification (scale bar 5 cm).
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case_images: Contrast-enhanced CT showed pancreatic enlargement and peri-pancreatic fluid, meeting criteria for mild acute pancreatitis by the revised Atlanta classification ( Figure 2 ).
case_images: Clinical time course and the serum level of pancreatic enzymes of the patient are shown. The vertical axis of the graph shows the serum levels of pancreatic enzymes [U/mL], and the horizontal axis shows the days from initiation of dose-dense doxorubicin plus cyclophosphamide (ddAC). Dexamethasone (DEX) was administered on day1-4.
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case_images: PMC10901989_01_fonc-14-1340419-g003.jpg
case_images: f3
case_images: With fasting and intravenous fluid administration, pancreatic enzymes rapidly decreased, and the abdominal pain resolved ( Figure 3 ).