case_images: PMC9885080_01
case_images: Microscopic morphology of the clonal gammadeltaT cell subtype. (A, B) show single cells found in a peripheral blood smear and show clear morphological characteristics; (C, D) are clustered cells found in the bone marrow aspirate smear with clear cytoplasmic protrusions.
case_images: fimmu-13-1103448-g001.jpg
case_images: PMC9885080_01_fimmu-13-1103448-g001.jpg
case_images: f1
case_images: Flow cytometry revealed the proliferation of gammadeltaT cells in the peripheral blood and bone marrow, accounting for 14.075% and 11.162% of all nucleated cells, respectively ( Supplementary Figures S1 ,  S2 ). TCR rearrangement, a characteristic population of lymphoid cells was found in the peripheral blood and bone marrow smears ( Figures 1A-D ). These cells were not prominent and thus easily overlooked in the initial microscopic examination.
case_images: (A) The timeline of the case. (B) The change in the patient's hemoglobin levels and gammadeltaT cell percentage in the total T-cell component in the peripheral blood sample over 10 months.
case_images: fimmu-13-1103448-g002.jpg
case_images: PMC9885080_01_fimmu-13-1103448-g002.jpg
case_images: f2
case_images: Flow cytometry revealed the proliferation of gammadeltaT cells in the peripheral blood and bone marrow, accounting for 14.075% and 11.162% of all nucleated cells, respectively ( Supplementary Figures S1 ,  S2 ). The patient's peripheral blood hemoglobin level increased from 37 to 95 g/L after 10 months of treatment, and his gammadeltaT cell percentage decreased from 14.075% to 6.637% ( Figure 2B ). The timeline of this case is demonstrated in  Figure 2A .