case_images: PMC3934697_01
case_images: Abdominal X-ray showing megacolon.
case_images: crg-0008-0007-g01.jpg
case_images: PMC3934697_01_crg-0008-0007-g01.jpg
case_images: F1
case_images: During the last admission to our hospital, an abdominal X-ray showed a massively distended large bowel (fig. 1), and an abdominal computed tomography scan did not reveal any mechanical obstruction (fig. 2).
case_images: Intraoperative picture of the dilated large bowel (after patient's personal permission).
case_images: crg-0008-0007-g03.jpg
case_images: PMC3934697_01_crg-0008-0007-g03.jpg
case_images: F3
case_images: During laparotomy (fig. 3) no obvious mechanical cause was found and a subtotal colectomy and Hartmann's procedure was performed.
case_images: Giant ganglion cells stained with neuron-specific enolase antibodies (x400).
case_images: crg-0008-0007-g04.jpg
case_images: PMC3934697_01_crg-0008-0007-g04.jpg
case_images: F4
case_images: A small number of isolated ganglion cells and giant submucosal ganglia (containing 7-15 ganglion cells) (fig. 4) were also detected in the submucosa.