case_images: PMC6598596_01
case_images: Year distribution of published papers and reported cases. In china, the first patient with clinical features similar to POEMS syndrome was reported in 1986. No new case was reported until 1988. From 1988 to 2010, the number of published papers and reported cases increased in fluctuation and peaked in 2009 and 2010, respectively. The number of patients was reported over 50 in 1994 and over 100 in 2004, reaching 161 in 2010 and declining gradually.
case_images: fimmu-10-01428-g0002.jpg
case_images: PMC6598596_01_fimmu-10-01428-g0002.jpg
case_images: F2
case_images: The number of patients was reported over 50 in 1994 and over 100 in 2004, reaching 161 in 2010 and declining gradually (Figure 2).
case_images: Regional distribution of reported cases. The top seven provinces on the number of reported cases were ordinally Beijing, Shanghai, Henan, Zhejiang, Liaoning, Hebei, and Jiangsu. There was no paper or case reported in Tibet, Taiwan, Hong Kong, and Macao.
case_images: fimmu-10-01428-g0003.jpg
case_images: PMC6598596_01_fimmu-10-01428-g0003.jpg
case_images: F3
case_images: There was no paper or case reported in Tibet, Taiwan, Hong Kong, and Macao (Figure 3).
case_images: Department distribution of published papers and reported cases. The top three departments on the number of published papers and reported cases were ordinally department of Neurology, department of Hematology, and department of Endocrinology.
case_images: fimmu-10-01428-g0004.jpg
case_images: PMC6598596_01_fimmu-10-01428-g0004.jpg
case_images: F4
case_images: The rest of the papers and cases were reported by other areas, which account for 41.84 and 21.28%, respectively (Figure 4).