case_images: PMC10984608_01
case_images: Photomicrographs of the breast and tumor. The interface between tumor (arrow) and breast parenchyma (star) (H&E, 100x).
case_images: autopsy-14-e2024484-g01.jpg
case_images: PMC10984608_01_autopsy-14-e2024484-g01.jpg
case_images: gf01
case_images: Photomicrographs of the tumor. A - Large cell neuroendocrine carcinoma composed of nests of large cells with prominent nucleoli (H&E, 600x); B - positive reaction to Chromogranin (200x); C - positive reaction to Synaptophysin (200x); D - Ki-67 showed a proliferation index of 50%.
case_images: autopsy-14-e2024484-g02.jpg
case_images: PMC10984608_01_autopsy-14-e2024484-g02.jpg
case_images: gf02
case_images: CgA and Syn, Ki67 50%, with lymphovascular invasion, ER 70%, progesterone receptors 1%, HER2 negative (score 1+ by immunohistochemistry), E-cadherin positive, CK19 positive and GATA3 positive (Figure 2). Carcinoma in situ was not found.