case_images: PMC5824501_01
case_images: (a) Clinical picture; (b) Photomicrograph (H&E, x10); (c) Photomicrograph (D2-40 stain, x10)
case_images: JOMFP-22-108-g001.jpg
case_images: PMC5824501_01_JOMFP-22-108-g001.jpg
case_images: F1
case_images: Provisional diagnosis as lymphangioma of palate was made [Figure 1a]. Few large cavernous spaces too were seen, mostly filled with lymph [Figure 1b]. Immunostaining with lymphatic marker D2-40 yield positive results [Figure 1c] and a diagnosis of lymphangioma (simplex) was confirmed.
case_images: PMC5824501_02
case_images: (a) Clinical picture; (b) Photomicrograph (H&E, x10); (c) Photomicrograph (D2-40 stain, x10)
case_images: JOMFP-22-108-g002.jpg
case_images: PMC5824501_02_JOMFP-22-108-g002.jpg
case_images: F2
case_images: The swelling was translucent in color with many fine, prominent radiating blood vessels [Figure 2a]. Stroma showed many small dilated endothelium-lined vessels containing homogeneous eosinophilic material suggestive of lymph vessel [Figure 2b]. Further positive staining with D2-40 marker confirmed the diagnosis [Figure 2c].
case_images: PMC5824501_03
case_images: (a) Clinical picture; (b) Photomicrograph (H&E, x10); (c) Photomicrograph (D2-40 stain, x10)
case_images: JOMFP-22-108-g003.jpg
case_images: PMC5824501_03_JOMFP-22-108-g003.jpg
case_images: F3
case_images: After 21/2 months, these red lesions reappeared and for the past 6-7 days, we observed protruded enlarged tongue with difficulty in closing mouth and many small elevated nodules with pink or yellowish [Figure 3a]. Underlying connective tissue stroma was loose fibro-cellular and showed numerous single endothelial lined vessels of variable sizes [Figure 3b]. Immunostaining with D2-40 marker was carried out, and the positive finding [Figure 3c] confirmed the diagnosis of capillary lymphangioma.
case_images: PMC5824501_04
case_images: (a) Clinical picture; (b) Photomicrograph (H&E, x10); (c) Photomicrograph (D2-40 stain, x10)
case_images: JOMFP-22-108-g004.jpg
case_images: PMC5824501_04_JOMFP-22-108-g004.jpg
case_images: F4
case_images: Provisional diagnosis as lymphangioma of the left buccal mucosa was made [Figure 4a]. Stroma revealed dilated endothelial lined vessels of variable sizes [Figure 4b]. These findings were suggestive of cavernous lymphangioma which was confirmed by positive staining by D2-40 marker [Figure 4c].