case_images: PMC11724620_01
case_images: Imaging examinations revealed a mass in the right thigh. (A) Ultrasound examination revealed a mass measuring 39x22 mm. (B-E). MRI revealed a mass measuring 140 mm x 50 mm x 55 mm. (B) Axial fat-suppressed PDWI exhibited a slightly higher signal. (C) Coronal T1WI displayed an equal signal. (D) Coronal PDWI exhibited a slightly higher signal, although the signal is not uniform. (E) Sagittal PDWI exhibited a slightly higher signal.
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case_images: Ultrasound examination revealed a 39 mm x 22 mm mass with indistinct borders, a regular shape, uneven internal echoes, and detectable blood flow signals (Figure 1A). The laminar demarcation is clear, and the laminar bundles are intact, though adjacent muscle groups are compressed (Figure 1B-E).
case_images: Pathological and histochemical staining findings of GCT. (A) The tumor was not well-defined and consisted of round or polygonal cells arranged in nests, sheets, or wide bands at 100x magnification. (B) The nuclei of most tumor cells are small and round, located in the center of the cells; the chromatin is compact or vacuolar, and the cytoplasm is abundant, eosinophilic, and finely granular at 200x magnification. (C-I). Immunohistochemistry revealed that the tumor cells tested positive for S100 (C), SOX-10 (D), Vimentin (E), NSE (F), CD56 (G), and H3K27Me3 (H) at 200x magnification. The Ki-67 labeling index is 15% (x200) (I).
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case_images: PMC11724620_01_ORR-17-1-g0002.jpg
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case_images: Under microscopic examination, the tumor was poorly demarcated and comprised round or polygonal cells arranged in nests, sheets, or broad bands, with fibrous connective tissue intervals of varying widths between the tumor cells (Figure 2A). Some local tumor cells exhibited mild to moderate atypia (Figure 2B). Immunohistochemical analysis revealed positive staining for S100, SOX-10, Vimentin, NSE, CD56, and H3K27Me3 in the tumor cells, with a Ki-67 labeling index of approximately 15% (Figure 2C-I).