case_images: PMC11074456_01
case_images: The pathology and immunohistochemical staining of thyroid specimens. The tumor tissue demonstrates a distinctive organization in nested clusters and sheets, characterized by the presence of large nuclei with intense staining. ((A) H&E, x200), ((B) H&E, x100). Immunohistochemical staining revealed that the tissue were positive for CA9 ((C) x200)[CD10 ((D) x200)[PAX-8 ((E) x100), negative for TG ((F) x100).
case_images: fonc-14-1350043-g003.jpg
case_images: PMC11074456_01_fonc-14-1350043-g003.jpg
case_images: f3
case_images: (A, B) Ultrasound of the thyroid and neck: (A) The largest mixed echogenic nodule in the right lobe of the thyroid gland, measuring about 27*20 mm, with clear borders, regular morphology, and showed abundant blood flow signals both within and around the area. (B) Multiple mixed echogenic nodules were observed in the right lobe of the thyroid gland, and some of the nodules exhibited punctate strong echoes. (C-H) The pathology and immunohistochemical staining of tyroid specimens. Tumor cells exhibit a growth pattern characterized by the formation of nests composed of cells with translucent cytoplasm, the nuclei of these cells are rounded, displaying varying sizes and prominent staining, with abundant interstitial blood sinuses. ((C) H&E, x100), ((D) H&E, x200). Immunohistochemical staining revealed that the tissue were positive for CD10 ((E) x200)[PAX-8 ((F) x200)[, negative for TG ((G) x200)[TPO ((H) x200).
case_images: fonc-14-1350043-g004.jpg
case_images: PMC11074456_01_fonc-14-1350043-g004.jpg
case_images: f4