case_images: PMC10467227_01
case_images: Widespread pink-to-erythematous papules, vesicles, and bullae with a few scattered pustules over the trunk.
case_images: 10.1177_2050313X231195467-fig1.jpg
case_images: PMC10467227_01_10.1177_2050313X231195467-fig1.jpg
case_images: fig1-2050313X231195467
case_images: A 53-year-old female with a history of Darier's disease diagnosed at the age of 47 years presented with a sudden onset of widespread pruritic vesicles and papules over her extremities and back (Figures 1 and 2).
case_images: Close-up of vesicles and crusted papules on the back.
case_images: 10.1177_2050313X231195467-fig2.jpg
case_images: PMC10467227_01_10.1177_2050313X231195467-fig2.jpg
case_images: fig2-2050313X231195467
case_images: A 53-year-old female with a history of Darier's disease diagnosed at the age of 47 years presented with a sudden onset of widespread pruritic vesicles and papules over her extremities and back (Figures 1 and 2).
case_images: (a) Low-power histologic image depicting prominent suprabasilar and intraepidermal vesicle with lymphocytic infiltrate acantholysis and dyskeratosis. Magnification 10x (b) High-power histologic image depicting suprabasilar and intraepidermal vesicle with dense dermal lympho-eosinophilic infiltrate. Magnification 40x.
case_images: 10.1177_2050313X231195467-fig3.jpg
case_images: PMC10467227_01_10.1177_2050313X231195467-fig3.jpg
case_images: fig3-2050313X231195467
case_images: A skin biopsy of an intact vesicle was performed showing prominent lymphocytic infiltrate with acantholysis and dyskeratosis, and in the area of the vesicle formation, there was a suprabasilar split with scattered eosinophils and occasional dyskeratotic cells (Figure 3).