case_images: PMC3928749_01
case_images: First bone scan performed on July 2010, showing bone metastases
case_images: IJNM-29-34-g001.jpg
case_images: PMC3928749_01_IJNM-29-34-g001.jpg
case_images: F1
case_images: Routine radiological and scintigraphic bone examination confirmed multifocal bone spread with a mixed osteolytic-osteosclerotic pattern [Figure 1].
case_images: First 18F-fluorodeoxyglucose positron emission tomography performed on 1st October 2010: Maximum intensity projection projection with some pathological uptakes in the sternum, ribs, both humeri and right femur
case_images: IJNM-29-34-g002.jpg
case_images: PMC3928749_01_IJNM-29-34-g002.jpg
case_images: F2
case_images: Numerous skeletal lesions were detected, with no metastases outside bones [Figure 2a]. Evident recalcification of bone lesions was seen on computed tomography (CT), while an increase of FDG uptake was clearly observable for almost all the bone lesions [Figures 2b, 3 and 4].
case_images: Second fluorodeoxyglucose positron emission tomography from 8 February 2013: Maximum intensity projection projection showing a marked increase of metabolism in sternal, humeral and costal lesions
case_images: IJNM-29-34-g003.jpg
case_images: PMC3928749_01_IJNM-29-34-g003.jpg
case_images: F3
case_images: Evident recalcification of bone lesions was seen on computed tomography (CT), while an increase of FDG uptake was clearly observable for almost all the bone lesions [Figures 2b, 3 and 4]. However, tumor/background ratios between physiological liver uptake and pathologic FDG accumulation displayed on Figures 3b (V right rib) and 4b (sternum) confirmed the visual impression of increased radiofarmaceutical uptake [Table 1].
case_images: Mixed osteolytic-osteosclerotyc lesion on VIII right rib at firs positron emission tomography-computed tomography examination (a) showing recalcification at second examination (b)
case_images: IJNM-29-34-g004.jpg
case_images: PMC3928749_01_IJNM-29-34-g004.jpg
case_images: F4
case_images: Evident recalcification of bone lesions was seen on computed tomography (CT), while an increase of FDG uptake was clearly observable for almost all the bone lesions [Figures 2b, 3 and 4].