case_images: PMC5726698_01
case_images: Firm, erythematous nodule, adhered and with central crust, measuring 2.0
  x 1.5cm, located on the left nasojugal groove
case_images: abd-92-05-s1-0118-g01.jpg
case_images: PMC5726698_01_abd-92-05-s1-0118-g01.jpg
case_images: f1
case_images: On dermatological examination, there was a firm, erythematous nodule, measuring 2.0 x 1.5 cm, adhered to the skin, with a central crust and located on the left nasojugal groove (Figure 1).
case_images: Spindle cell neoplasia (*) diffusely infiltrating the dermis and
  epidermis (arrow) (Hematoxylin & eosin, X200)
case_images: abd-92-05-s1-0118-g02.jpg
case_images: PMC5726698_01_abd-92-05-s1-0118-g02.jpg
case_images: f2
case_images: An incisional biopsy was performed, and the histology revealed a poorly differentiated malignancy, with a spindle cell pattern, diffusely infiltrating the dermis (Figures 2 and 3).
case_images: Detail of spindle cell with bulky, elongated, cigar-shaped nuclei
  (Hematoxylin & eosin, X400)
case_images: abd-92-05-s1-0118-g03.jpg
case_images: PMC5726698_01_abd-92-05-s1-0118-g03.jpg
case_images: f3
case_images: An incisional biopsy was performed, and the histology revealed a poorly differentiated malignancy, with a spindle cell pattern, diffusely infiltrating the dermis (Figures 2 and 3).
case_images: Positive staining for HUC-1 (A) and desmin (B) (X200)
case_images: abd-92-05-s1-0118-g04.jpg
case_images: PMC5726698_01_abd-92-05-s1-0118-g04.jpg
case_images: f4
case_images: Immunohistochemistry was positive for specific muscle actin (HHF-35), smooth muscle actin (HUC-1) and Ki-67 in 10% of the tumor cells (Figure 4).