case_images: PMC11809126_01
case_images: Liver biopsy. Haematoxylin-Eosin staining showing micro/macrovascular steatosis, hepatocyte ballooning and periportal lymphocytic infiltrations (Left). Reticulin staining depicting the normal liver parenchyma (Right).
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case_images: PMC11809126_01_JVH-32-0-g001.jpg
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case_images: Next, liver biopsy was performed showing non-specific alterations consistent with chronic-active hepatitis (Figure 1).
case_images: Total bilirubin, ALT and HEV RNA values during the disease course including treatment with ribavirin.
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case_images: PMC11809126_01_JVH-32-0-g002.jpg
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case_images: Liver biochemistry was normalised 30 days later and remained in normal values (Figure 2). In line with this, HEV RNA significantly decreased 15 days post-treatment (9.48 x 103 IU/mL) and was undetectable 1 month after RBV administration, indicating sustained virological response (SVR) (Figure 2).