case_images: PMC7908392_01
case_images: PMC7908392_02
case_images: A) computed tomography scan showing a large mass constricting the bowel lumen at the ileocecal junction; B) photo of the resected surgical specimen (right hemicolectomy)
case_images: PAMJ-36-223-g001.jpg
case_images: PMC7908392_02_PAMJ-36-223-g001.jpg
case_images: F1
case_images: X-rays of the chest and abdomen were indicative for large bowel obstruction, a finding that was confirmed by computed tomography (CT) scan (Figure 1), which also revealed a large mass of the ascending colon constricting the bowel lumen, extending in a length of about 14cm with minimal involvement of the terminal ileum.
case_images: A) monomorphic neoplastic lymphoid cells and interspersed histiocytes consistent with the pathognomonic "starry sky" appearance of BL; B) infiltration of submucosa and complete destruction of the normal colonic architecture from BL (H-E x 100); C) immunohistochemistry showing CD20 stain positivity (x100); D) C-myc positivity in >80% of neoplastic cells
case_images: PAMJ-36-223-g002.jpg
case_images: PMC7908392_02_PAMJ-36-223-g002.jpg
case_images: F2
case_images: The cytogenetical analysis revealed proto-oncogene (c-myc) rearrangement (>80%), BCL-2 (-), Ki-67 100% (Figure 2).