case_images: PMC3271029_01
case_images: An abdominal computed tomography (CT) scan showing a heterogeneous mass (3 cm x 4 cm) located in the lower part of the stomach body. The tumor is indicated with an arrow.
case_images: 1477-7819-10-6-1.jpg
case_images: PMC3271029_01_1477-7819-10-6-1.jpg
case_images: F1
case_images: Abdominal CT scan showed a well-defined, heterogeneous mass (3 x 4 m) which was located in the lower part of the stomach body (Figure 1).
case_images: Gastric endoscopy confirmed an ulcerated tumor with bleeding along the lesser curvature of the proximal stomach.
case_images: 1477-7819-10-6-2.jpg
case_images: PMC3271029_01_1477-7819-10-6-2.jpg
case_images: F2
case_images: Gastric endoscopy showed the ulcerated tumor with bleeding along the lesser curvature of the proximal stomach (Figure 2) and a submucosal nodule that measured about 3 cm in diameter in the lower part of the stomach body (Figure 3).
case_images: Gastric endoscopy showing a submucosal nodule that measured about 3 cm in diameter in the lower part of the stomach body.
case_images: 1477-7819-10-6-3.jpg
case_images: PMC3271029_01_1477-7819-10-6-3.jpg
case_images: F3
case_images: Gastric endoscopy showed the ulcerated tumor with bleeding along the lesser curvature of the proximal stomach (Figure 2) and a submucosal nodule that measured about 3 cm in diameter in the lower part of the stomach body (Figure 3).
case_images: Macroscopic examination of a total gastrectomy specimen showing Borrman type-2 tumor measuring 5 x 6 cm (black arrow) and submucosal nodule measuring 3 x 4 cm in the stomach (white arrow).
case_images: 1477-7819-10-6-4.jpg
case_images: PMC3271029_01_1477-7819-10-6-4.jpg
case_images: F4
case_images: Macroscopic examination of the total gastrectomy specimen showed Borrman type-2 tumor measuring 5 x 6 cm and submucosal nodule measuring 3 x 4 cm in the stomach (Figure 4).
case_images: Microscopic examination of the proximal tumor in the stomach demonstrating typical histological findings of adenocarcinoma (A). In addition, histopathological examination of the submucosal nodule revealed GIST of the low-risk category, composed of cytologically bland spindle cells with a low mitotic index (< 5) (B). Immunohistochemistry indicated strong staining for CD34 (C) and C-kit (D), while negative results were observed for S-100 (E) and SMA (F).
case_images: 1477-7819-10-6-5.jpg
case_images: PMC3271029_01_1477-7819-10-6-5.jpg
case_images: F5
case_images: On histopathological examination, the Borrman type-2 tumor gastric tumor showed transmural infiltration by a poorly differentiated diffuse adenocarcinoma (Figure 5A). The immunohistochemistry indicated strong staining for CD34 and C-kit, while expressions of SMA and S-100 were negative (Figure 5B-F).