case_images: PMC11249612_01
case_images: Fundus photo, OCT images, FA, and ICGA at the patient's first visit at Oita University Hospital. The fundus photo (a), OCT (b: horizontal section, c: vertical section), and the images of FA (d, left) and ICGA (d, right) of his left eye at the first visit of the patient, a 63-year-old male. The fundus photo shows retinal hemorrhage, cotton wool spots, and narrowing of the inferior arcade vein (a), and OCT shows ME (b, c). The FA and ICGA of the left eye revealed an NPA of the inferior retina (d). BCVA at the first visit was 0.1. OCT, optical coherence tomography; FA, fluorescein angiography; ICGA, indocyanine green angiography; NPA, non-perfusion area.
case_images: cop-2024-0015-0001-539343_F01.jpg
case_images: PMC11249612_01_cop-2024-0015-0001-539343_F01.jpg
case_images: F1
case_images: Fundus examination revealed a retinal hemorrhage, cotton wool spots, and narrowing of the inferior arcade vein (Fig. 1a). Optical coherence tomography revealed ME in the left eye (Fig. 1b, c). Fluorescein angiography and indocyanine green angiography revealed a non-perfusion area in the inferior retina of the left eye (Fig. 1d).
case_images: OCT images after IVA injections. OCT images at 1 month (a: horizontal section, b: vertical section), 6 months (c: horizontal section, d: vertical section), and 7 months (e: horizontal section, f: vertical section) after the first visit. ME was substantially decreased after the first IVA injection (a, b). A relapse of ME after 6-month treatment with the initial IVA injection was observed (c, d), which was promptly decreased by an additional IVA injection (e, f). There were segmental retinal thinning and nerve fiber loss in the inferior area on vertical section of OCT (f). OCT, optical coherence tomography.
case_images: cop-2024-0015-0001-539343_F02.jpg
case_images: PMC11249612_01_cop-2024-0015-0001-539343_F02.jpg
case_images: F2
case_images: ME decreased substantially after the first IVA injection (Fig. 2a, b). ME relapse was observed 6 months after the initial IVA injection (Fig. 2c, d), which promptly decreased upon receiving an additional IVA injection (Fig. 2e, f). There was a segmental retinal thinning and nerve fiber loss in the inferior area on vertical sections of optical coherence tomography (Fig. 2f, 3c).
case_images: Fundus photo and OCT images at the last visit. The fundus photo (a) and OCT images (b: horizontal section, c: vertical section) at the last visit (9 months after the first visit). The fundus photo shows only narrowing of the inferior arcade vein and the scar from RP in the inferior area of the retina (a), and there is no ME (b, c). Segmental retinal thinning and nerve fiber loss were still seen in the inferior area (c). BCVA had improved to 0.8 at that time. OCT, optical coherence tomography.
case_images: cop-2024-0015-0001-539343_F03.jpg
case_images: PMC11249612_01_cop-2024-0015-0001-539343_F03.jpg
case_images: F3
case_images: RP in the inferior area of the retina. Retinal hemorrhage and cotton wool spots were not detected, the caliber of the retinal artery returned to normal (Fig. 3a), and no ME was detected (Fig. 3b, c). There was a segmental retinal thinning and nerve fiber loss in the inferior area on vertical sections of optical coherence tomography (Fig. 2f, 3c).