case_images: PMC10500233_01
case_images: Abdominal CT. A 2.5 cm lesion in the left lobe of the liver, with dense contrast-enhancement in both arterial and late phases.
case_images: NCI-10-524-g001.jpg
case_images: PMC10500233_01_NCI-10-524-g001.jpg
case_images: F1
case_images: Abdominal computed tomography (CT) revealed the lesion enhanced both arterial and late phases (Fig. 1).
case_images: Hematoxylin and eosin staining. (A) Low magnification reveals multiple capillaries with variable sizes and accompanying congestion. The infiltrative appearance raises suspicion of angiosarcoma. (B) At high magnification, anastomosing sinusoidal channels lined by flattened endothelium lacking cytologic atypia and mitosis are observed.
case_images: NCI-10-524-g002.jpg
case_images: PMC10500233_01_NCI-10-524-g002.jpg
case_images: F2
case_images: The neoplastic cells usually revealed the morphology of flattened epithelium and occasional hobnail appearance (Fig. 2).
case_images: Immunohistochemistry. A and B indicate CD31 and CD34 positive neoplastic cells, respectively. C and D show Heppar and Cam 5.2 negativity, respectively.
case_images: NCI-10-524-g003.jpg
case_images: PMC10500233_01_NCI-10-524-g003.jpg
case_images: F3
case_images: Desmin, Cam 5.2, Heppar, HMB45, and HHV8 were negative (Fig. 3).