case_images: PMC10656801_01
case_images: Clinical presentation of mantle cell lymphoma. Top row: Mantle cell lymphoma presenting as an edematous diffuse morbilliform rash, biopsy site highlighted in the second panel in red. Bottom row: similar presentation and minimal improvement after withdrawal of offending medications and one week of topical steroids.
case_images: 10.1177_2050313X231212994-fig1.jpg
case_images: PMC10656801_01_10.1177_2050313X231212994-fig1.jpg
case_images: fig1-2050313X231212994
case_images: On examination, he was noted to have edematous pink macules and papules on his trunk and extremities, most prominent over his lower chest and back (Figure 1, top row). He was started on topical triamcinolone ointment twice daily with minimal improvement after 1 week (Figure 1, bottom row).
case_images: Punch biopsy of the left lower abdomen showing (a) dense dermal infiltrate surrounding the follicle; (b) atypical monomorphic lymphocytes; (c) ovoid nuclei and open and dispersed chromatin (highlighted by red arrows); and (d) positive cyclin D1 staining.
case_images: 10.1177_2050313X231212994-fig2.jpg
case_images: PMC10656801_01_10.1177_2050313X231212994-fig2.jpg
case_images: fig2-2050313X231212994
case_images: A punch biopsy was obtained which demonstrated atypical monomorphic lymphocytes with ovoid nuclei and open and dispersed chromatin (Figure 2).