case_images: PMC11113035_01
case_images: Right breast enlargement with distortion of the nipple-areolar complex.
case_images: 10.1177_2050313X241255808-fig1.jpg
case_images: PMC11113035_01_10.1177_2050313X241255808-fig1.jpg
case_images: fig1-2050313X241255808
case_images: On clinical examination, a large, ill-defined, non-tender mass involving the entire right breast was noted which was also close to the nipple-areolar complex (Figure 1).
case_images: Magnetic resonance imaging images of the tumour. (a) Post-contrast enhancement in the posterior aspect of the tumour with retro areolar non-enhancing area with some serpiginous enhancement in the periphery. (b) T1-weighted view - Heterogenous central low and peripheral high-intensity signal. (c) T2-weighted view - Diffuse enhancement, the high-intensity signal in the peripheral area and heterogeneous signal in the retro areolar region. (d) TIRM sagittal - High signal lesion diffusely involving right breast with central necrotic area in a medial quadrant, infiltrating into the subcutaneous tissue.
case_images: 10.1177_2050313X241255808-fig2.jpg
case_images: PMC11113035_01_10.1177_2050313X241255808-fig2.jpg
case_images: fig2-2050313X241255808
case_images: A breast neoplasm such as angiosarcoma was the likely diagnosis on MRI interpretation (Figure 2).
case_images: Macroscopic and microscopic images of the tumour. (a) Macroscopically pink solid tumour mass. (b) Vascular channels with bland endothelial cells. (H &E X200). (c) Strong nuclear staining of the endothelium (IHC-ERG X200). (d) Ki 67 proliferative index of 50% (IHC Ki 67X200).
case_images: 10.1177_2050313X241255808-fig3.jpg
case_images: PMC11113035_01_10.1177_2050313X241255808-fig3.jpg
case_images: fig3-2050313X241255808
case_images: All margins were free of tumour/R0 resection (Figure 3).