case_images: PMC3586447_01
case_images: Computed tomography (CT) of paranasal sinuses and orbit showing mass (arrow) occupying the entire left ethmoid and sphenoid sinus extending into left nasal cavity causing erosion of nasal septum, extending into orbit and intracranial extension into basifrontal area (before chemoradiation and after chemoradiation).
case_images: CRIM.ONCMED2013-728479.001.jpg
case_images: PMC3586447_01_CRIM.ONCMED2013-728479.001.jpg
case_images: fig1
case_images: Computed tomography (CT) of paranasal sinuses and orbit revealed soft-tissue mass occupying the entire left ethmoid and sphenoid sinus extending into left nasal cavity causing erosion of nasal septum, extending into orbit and intracranial extension into basifrontal area (Figure 1(a)). Reassessment showed that the tumour had regressed completely (Figure 1(b)).
case_images: (haematoxylin and eosin x100): Showing poorly differentiated malignant neoplasm with neuroendocrine differentiation.
case_images: CRIM.ONCMED2013-728479.002.jpg
case_images: PMC3586447_01_CRIM.ONCMED2013-728479.002.jpg
case_images: fig2
case_images: Biopsy from nasal mass was reported as poorly differentiated malignant neoplasm with neuroendocrine differentiation (Figure 2).
case_images: Neuroendocrine cells showing synaptophysin positivity (arrow). (Immunoperoxidase technique, HPR polymerase method x100.)
case_images: CRIM.ONCMED2013-728479.003.jpg
case_images: PMC3586447_01_CRIM.ONCMED2013-728479.003.jpg
case_images: fig3
case_images: Immunohistochemistry (IHC) revealed that neoplastic cells were positive for cytokeratin, synaptophysin, and chromogranin and negative for S-100 (Figure 3).