case_images: PMC10837056_01
case_images: Case 1 images are in the left column (panels A-D) and case 2 in the right column (panels E-H). A and E. Coronal reconstructions using high resolution (1.25 mm slice thickness) unenhanced head CT demonstrates areas of small acute hemorrhage (arrow). B and F. Axial T2*GRE image demonstrating cerebral microbleeds (arrows). C and G. Axial diffusion weighted image (DWI) in the left and apparent diffusion coefficient (ADC) in the right for each case demonstrating hypointense lesion surrounded by hyperintense rim in case 1 (arrow) and hyperintense DWI signal with corresponding hypointense ADC signal for case 2 (arrows). D. DWI (left) and T2*GRE (right) images predating the occurrence of CMB show absence of the lesions for case 1. H. Axial and coronal high resolution (1.25 mm slice thickness) unenhanced head CT predating the occurrence of CMB in case 2 demonstrating absence of the acute hemorrhage (arrow).
case_images: gr1.jpg
case_images: PMC10837056_02_gr1.jpg
case_images: fig0001
case_images: A routine unenhanced head CT scan was unremarkable, however, high-resolution CT (1.25 mm slice thickness) showed a small hyperdensity in the right thalamus/internal capsule region (Fig. 1E), which was absent on a previous head CT scan from 2 years earlier (Fig. 1H). Brain MRI performed the same day showed a CMB in the same region as the lesion observed on the CT (Fig. 1F). The lesion demonstrated subtle restricted diffusion on DWI (Fig. 1G).
case_images: PMC10837056_02
case_images: Case 1 images are in the left column (panels A-D) and case 2 in the right column (panels E-H). A and E. Coronal reconstructions using high resolution (1.25 mm slice thickness) unenhanced head CT demonstrates areas of small acute hemorrhage (arrow). B and F. Axial T2*GRE image demonstrating cerebral microbleeds (arrows). C and G. Axial diffusion weighted image (DWI) in the left and apparent diffusion coefficient (ADC) in the right for each case demonstrating hypointense lesion surrounded by hyperintense rim in case 1 (arrow) and hyperintense DWI signal with corresponding hypointense ADC signal for case 2 (arrows). D. DWI (left) and T2*GRE (right) images predating the occurrence of CMB show absence of the lesions for case 1. H. Axial and coronal high resolution (1.25 mm slice thickness) unenhanced head CT predating the occurrence of CMB in case 2 demonstrating absence of the acute hemorrhage (arrow).
case_images: gr1.jpg
case_images: PMC10837056_02_gr1.jpg
case_images: fig0001
case_images: A routine unenhanced head CT scan was unremarkable, however, high-resolution CT (1.25 mm slice thickness) showed a small hyperdensity in the right thalamus/internal capsule region (Fig. 1E), which was absent on a previous head CT scan from 2 years earlier (Fig. 1H). Brain MRI performed the same day showed a CMB in the same region as the lesion observed on the CT (Fig. 1F). The lesion demonstrated subtle restricted diffusion on DWI (Fig. 1G).