case_images: PMC10773876_01
case_images: (A) T1-weighted brain magnetic resonance imaging with contrast enhancement showing increased vessel enhancement in the cerebral sulci (left panel) and bilateral dura thickening (right panel), suggesting an inflammatory or infectious process. (B) Bone marrow smear showing proliferated macrophages with phagocytosis of nucleated cell (arrow, left panel) and platelets (arrow, right panel) (Wright-Giemsa stain, x 1000). (C) Abdominal computed tomography showing normal spleen size on day 12 of admission (arrowhead, left panel), and splenomegaly (arrowhead, right panel), with the length measuring 12.7 cm on day 18 of admission. (D) Diffuse skin petechiae.
case_images: fimmu-14-1296575-g001.jpg
case_images: PMC10773876_01_fimmu-14-1296575-g001.jpg
case_images: f1
case_images: The brain magnetic resonance imaging with gadolinium enhancement showed increased vessel enhancement in the cerebral sulci and bilateral dura thickening ( Figure 1A ), suggesting an inflammatory or infectious process. Figure 1B ). Furthermore, new-onset hypertriglyceridemia (478 mg/dL on day 12 of admission; initial value, 84 mg/dL), high serum ferritin level (4501 ug/L;  Table 1 ), and new-onset splenomegaly ( Figure 1C ) were found. Sepsis and MODS developed, including jaundice (bilirubin, 16.8 mg/dL), acute kidney injury (creatinine, 4.5 mg/dL), acute respiratory distress syndrome (PaO2/FiO2 ratio < 100), and disseminated intravascular coagulation with multiple skin petechiae ( Figure 1D ).