case_images: PMC10516137_01
case_images: PMC10516137_02
case_images: Video shows the clinical features of the patient with MAPT mutation. Showing (A) slowing or horizontal and vertical saccades. (B) asymmetric rest tremor of upper and lower limbs with re-emergence and position specificity, and mild right-sided bradykinesia of upper and lower limbs. (C) Worsening of tremor when pouring water between two cups. (written consent was obtained from the patients for the video to be submitted/published if accepted in this journal).
case_images: .jpg
case_images: PMC10516137_02_.jpg
case_images: V1
case_images: Magnetic resonance imaging (MRI) scans showed progressive frontotemporal and mesial temporal atrophy (left > right) as well as stable post-operative surgical changes. (Figure 1A to 1F).
case_images: Serial coronal magnetic resonance fluid attenuated inversion recovery images taken at different time points relative to the clinical presentation. A, C, E show anterior frontotemporal regions and B, D, F show mesial temporal structures. Progressive atrophy of anterior temporal (arrow) and mesial temporal lobe structures (arrowhead) is demonstrated. Left frontal lobe changes secondary to meningioma surgery are also seen.
case_images: tohm-13-1-804-g1.jpg
case_images: PMC10516137_02_tohm-13-1-804-g1.jpg
case_images: F1
case_images: There was no significant midbrain atrophy (Figure 2).