case_images: PMC10559532_01
case_images: (a-c) Admission magnetic resonance imaging: large expansive intraparenchymal lesion in the left superior temporal gyrus with vasogenic edema, mass effect, and midline shift. Mild vascular engorgement of M2/M3 branches of the left middle cerebral artery.
case_images: SNI-14-310-g001.jpg
case_images: PMC10559532_01_SNI-14-310-g001.jpg
case_images: F1
case_images: Magnetic resonance imaging (MRI) revealed a 3.3 x 2.4 cm lesion in the left temporal lobe with hyposignal on T2, an intermediate signal on T1, diffusion restriction, and intense homogeneous contrast enhancement [Figures 1, a-c, respectively].
case_images: Pathology and immunohistochemical staining: primary central nervous system diffuse large B-cell lymphoma cells with positive staining for CD20, C-MYC, BCL-2, BCL-6, and MUM1, respectively, from (a-f) (original magnification x200).
case_images: SNI-14-310-g002.jpg
case_images: PMC10559532_01_SNI-14-310-g002.jpg
case_images: F2
case_images: Histopathological and immunohistochemistry confirmed DLBCL [Figure 2].
case_images: (a-c) Control magnetic resonance imaging 2-month post-surgery: left pterional craniotomy with extra-axial residual blood collection. Partially resected infiltrative left temporal lesion with extension to the frontal and parietal lobes. Persistent contrast-enhancing lesion with mass effect on the left lateral ventricle.
case_images: SNI-14-310-g003.jpg
case_images: PMC10559532_01_SNI-14-310-g003.jpg
case_images: F3
case_images: Two-month postoperative, MRI showed partial resection of the left temporal lobe lesion [Figure 3].
case_images: (a-c) Control magnetic resonance imaging after two cycles of combined chemotherapy: left pterional craniotomy with extra-axial residual surgical hemostatic material (red arrows). Extensive parenchymal left temporal resection with extension into the frontal and parietal lobes. No contrast-enhancing lesion or midline shift.
case_images: SNI-14-310-g004.jpg
case_images: PMC10559532_01_SNI-14-310-g004.jpg
case_images: F4
case_images: Control MRI revealed the absence of the previous lesion [Figure 4], suggesting a complete response.
case_images: Diffusion tensor imaging and fiber tractography: marked reduction of fractional anisotropy (FA) in the left inferior longitudinal fasciculus and anterior corona radiata, suggesting fiber injury. Slight reduction of FA in the corpus callosum. No evidence of intracranial expansile process, hemorrhage, extra-axial collections, or midline shift.
case_images: SNI-14-310-g005.jpg
case_images: PMC10559532_01_SNI-14-310-g005.jpg
case_images: F5
case_images: Diffusion tensor imaging, fiber tractography (DTI tractography), and fractional anisotropy data were collected [Figure 5], the Western aphasia battery was applied, and the aphasia quotient calculated to assess residual symptoms, which showed mild sensory aphasia related to naming objects.