case_images: PMC9233607_01
case_images: CT chest showing involvement of the right lower paratracheal lymphnodes (Station 4R).
case_images: CRIPU2022-5453420.001.jpg
case_images: PMC9233607_01_CRIPU2022-5453420.001.jpg
case_images: fig1
case_images: Multiple lytic lesions in the dorsal vertebrae and a sclerotic focus in the manubrium sternum were identified (Figures 1 and 2).
case_images: CT chest. (a) Confluent prevascular nodal mass measuring 4.1 x 2.4 cm. (b) Right hilar lymph node measuring 2.5 x 3.1 cm.
case_images: CRIPU2022-5453420.002.jpg
case_images: PMC9233607_01_CRIPU2022-5453420.002.jpg
case_images: fig2
case_images: Multiple lytic lesions in the dorsal vertebrae and a sclerotic focus in the manubrium sternum were identified (Figures 1 and 2).
case_images: Diff-Quik smear shows clusters of cohesive neoplastic, epithelioid cells with a small amount of cytoplasm (a). The alcoholol-fixed smears demonstrate individual and clustered neoplastic cells with coarse chromatin, ill-defined borders, and nuclear grooves (c, d). The corresponding cellblock material is shown in (b).
case_images: CRIPU2022-5453420.003.jpg
case_images: PMC9233607_01_CRIPU2022-5453420.003.jpg
case_images: fig3
case_images: Cytoplasmic extensions were appreciated in some areas (Figure 3).
case_images: GFAP is immunoreactive in the tumor cells (a). (b) Strong positivity for synaptophysin. S100 protein immunostain demonstrates strong and diffuse positivity (c). Keratin is negative (not shown).
case_images: CRIPU2022-5453420.004.jpg
case_images: PMC9233607_01_CRIPU2022-5453420.004.jpg
case_images: fig4
case_images: Tumor cells, however, were immunoreactive for GFAP, synaptophysin, and S100 protein (Figure 4).
case_images: Treatment timeline. Abbreviations: CCRT: concurrent chemoradiation; Adj TMZ: adjuvant temozolomide; XRT: radiation therapy; DD: dose dense.
case_images: CRIPU2022-5453420.005.jpg
case_images: PMC9233607_01_CRIPU2022-5453420.005.jpg
case_images: fig5
case_images: Treatment timeline is shown in Figure 5.