case_images: PMC9127150_01
case_images: Example of opioid object + precipitant base pair exposure episode eligible for inclusion. The presence of candidate precipitant-unexposed person-days before and after candidate precipitant-exposed person-days is indicative of a bi-directional implementation of the self-controlled case series design.
case_images: fphar-13-845485-g001.jpg
case_images: PMC9127150_01_fphar-13-845485-g001.jpg
case_images: F1
case_images: Figure 1 provides a graphical representation of the design.
case_images: PMC9127150_02