case_images: PMC2892660_01
case_images: Solitary fibrous tumour of the anterior thoracic wall.
case_images: CRM2010-257167.001.jpg
case_images: PMC2892660_01_CRM2010-257167.001.jpg
case_images: fig1
case_images: On physical examination, the tumour appeared as an exophytic pseudolobulated tan-pink mass, measuring 18 x 10 cm, with multiple hemorrhagic foci, yellow and black necrosis, and localized infection with purulent exudates (Figure 1).
case_images: Tumour specimen after resection.
case_images: CRM2010-257167.002.jpg
case_images: PMC2892660_01_CRM2010-257167.002.jpg
case_images: fig2
case_images: The patient underwent wide local resection of the tumour by a surgical team consisting of thoracic and plastic surgeons (Figure 2).
case_images: Immediate postoperative result after tumour resection and reconstruction with bilateral pectoralis major advancement flaps and split-thickness skin graft.
case_images: CRM2010-257167.003.jpg
case_images: PMC2892660_01_CRM2010-257167.003.jpg
case_images: fig3
case_images: For the reconstruction of the wide defect both pectoralis major advancement flaps were mobilized and covered with a partial-thickness skin graft (Figure 3). 
case_images: Malignant solitary fibrous tumour demonstrating patternless arrangement of spindle cells and areas with very high cellularity. The spindle cells have moderate cytological atypia, and three mitoses in mitotically active fields are evident (HE x400).
case_images: CRM2010-257167.004.jpg
case_images: PMC2892660_01_CRM2010-257167.004.jpg
case_images: fig4
case_images: Microscopically spindle cells were arranged patternless, with a characteristic hemangiopericytoma-like morphology, and there were areas with very high cellularity (Figures 4 and 5).
case_images: (a) Malignant solitary fibrous tumour demonstrating uniform immunoreactivity for CD34 (CD34 x400) with hemangiopericytoma-like morphology. (b) A hyalinized vessel with thrombus in it is evident (HE x200), as well as (c) hyalinized staghorn vessels of tumour, that are centered (CD34 x200). (d) Areas of hypo- and hypercellularity (HE x200) are evident.
case_images: CRM2010-257167.005.jpg
case_images: PMC2892660_01_CRM2010-257167.005.jpg
case_images: fig5
case_images: Microscopically spindle cells were arranged patternless, with a characteristic hemangiopericytoma-like morphology, and there were areas with very high cellularity (Figures 4 and 5).