case_images: PMC8650131_01
case_images: Pedigree of the patient's family. Squares represent male family members, while circles represent female family members. The diamond symbol indicates unknown gender. Slash indicates that the family member is deceased. Black symbols represent individuals with ID/DD, and blank symbols represent unaffected family members. The gray filled symbols indicates balanced translocation carriers.
case_images: fgene-12-741607-g001.jpg
case_images: PMC8650131_01_fgene-12-741607-g001.jpg
case_images: F1
case_images: Facial features, hand and foot characteristics of patients with more obvious symptoms in the family.
case_images: fgene-12-741607-g002.jpg
case_images: PMC8650131_01_fgene-12-741607-g002.jpg
case_images: F2
case_images: She walks like a duck (Figure 2A). Except for typical hand bones and joints, the remaining clinical manifestations were the same as IV-10 (Figure 2B). He was illiterate and had no numeracy skills (Figure 2C). His body posture and clinical manifestations were the same as for patient IV-15 (Figure 2D).