case_images: PMC11129564_01
case_images: Results of gastroscopy after admission. (a) Esophageal lumen stenosis, resulting in endoscopy cannot pass, mucosal hyperplasia, erosion, from the incisors about 33 cm visible mucosal erosion, the vascular texture is not clear. (b) Esophageal mucosa uneven, local hyperplasia, mucosal erosion, after biopsy, local bleeding.
case_images: 10.1177_2050313X241252743-fig1.jpg
case_images: PMC11129564_01_10.1177_2050313X241252743-fig1.jpg
case_images: fig1-2050313X241252743
case_images: Endoscopic manifestations included esophageal stenosis (Figure 1(a)), mucosal color changes, thickening, transparency and vascular structure changes, mucosal erosion, plaque, and other morphological changes (Figure 1(b)).
case_images: (a) The patient underwent a chest-enhanced CT examination after admission. (b) Results of upper abdominal enhanced CT examination. Based on the chest-enhanced CT examination, the patient has esophageal stenosis caused by the compression of the esophageal tumor.
case_images: 10.1177_2050313X241252743-fig2.jpg
case_images: PMC11129564_01_10.1177_2050313X241252743-fig2.jpg
case_images: fig2-2050313X241252743
case_images: After admission, the patient underwent chest-enhanced CT, which revealed that the patient had esophageal stenosis (Figure 2(a)). Upper abdominal-enhanced CT revealed that the patient had liver space occupied, and the AFP level was also very high, suggesting the possibility of liver cancer (Figure 2(b)).
case_images: Patients with esophageal and liver biopsy. (a) The results of gastroscopy pathology showed squamous cell carcinoma. (b) The results of the liver biopsy showed hepatocellular carcinoma. (H&E, 400x).
case_images: 10.1177_2050313X241252743-fig3.jpg
case_images: PMC11129564_01_10.1177_2050313X241252743-fig3.jpg
case_images: fig3-2050313X241252743
case_images: After admission, according to the results of the endoscopy, the patient's pathology improved, suggesting esophageal squamous cell carcinoma (Figure 3(a)). After communication with the patient's family, the liver puncture examination improved, and the pathology indicated HCC (Figure 3(b)).
case_images: Results of liver biopsy immunohistochemistry. (a) Cytokeratin (CK) 19 was positive. (b) CD10 was positive. (c) CK 7 was partially positive. (d) Ki67 was about 70% positive. (e) CD34 was positive in the hepatic sinusoid.
case_images: 10.1177_2050313X241252743-fig4.jpg
case_images: PMC11129564_01_10.1177_2050313X241252743-fig4.jpg
case_images: fig4-2050313X241252743
case_images: Based on the diagnosis of a malignant liver tumor, Ki67 was positive in approximately 70% of the patients, considering the rapid growth of tumor cells (Figure 4).
case_images: Transcatheter arterial chemoembolization was performed after the diagnosis of liver cancer was confirmed (a)-(c).
case_images: 10.1177_2050313X241252743-fig5.jpg
case_images: PMC11129564_01_10.1177_2050313X241252743-fig5.jpg
case_images: fig5-2050313X241252743
case_images: TACE is the most common palliative therapy for HCC.   Moreover, TACE combined with lenvatinib was used for the treatment of HCC (Figure 5).