case_images: PMC4063997_01
case_images: Three generation pedigree of family A. Bladder cancer shown as shaded. - indicates other cancer.
case_images: 40064_2014_1001_Fig1_HTML.jpg
case_images: PMC4063997_01_40064_2014_1001_Fig1_HTML.jpg
case_images: Fig1
case_images: No parental siblings had a history of any relevant cancer (Figure 1).Family B.
case_images: Four generation pedigree of family B. Bladder cancer shown as shaded. - indicates other cancer.
case_images: 40064_2014_1001_Fig2_HTML.jpg
case_images: PMC4063997_01_40064_2014_1001_Fig2_HTML.jpg
case_images: Fig2
case_images: The proband's daughter III.1 developed stage III bladder cancer aged 76, a son III.6 was diagnosed with stage II UCC bladder at age 50 (also a HFE gene carrier) a daughter III.4 (a smoker) developed lung cancer at age 65, and a son III.5 developed colon cancer at age 60 (Figure 2).