case_images: PMC11104548_01
case_images: (a) Computed tomography of the pulmonary artery in the postero-anterior view showing a large thrombus in the main, right, and left pulmonary artery branches. (b) Computed tomography (CT) chest clearly showing a large saddle embolus in cross-sectional view, (c) pulmonary angiography showing a large thrombus more to in right branches. (d) CT chest post-EkoSonic supported tissue plasminogen activator thrombolysis and no thrombus in cross-sectional view
case_images: HV-25-42-g001.jpg
case_images: PMC11104548_01_HV-25-42-g001.jpg
case_images: heartviews.heartviews_103_23-F1
case_images: A PA catheter was placed in the main PA to conduct pulmonary angiography [Figure 1c], and baseline pulmonary artery pressure (PAP) was found to be markedly raised 96/32 (mean 64) mmHg [Figure 2b]. A repeat pulmonary angiography confirmed the dissolution of the saddle thrombus in main pulmonary artery, same were the findings of follow-up CT pulmonary angiography [Figure 1d].
case_images: (a) EkoSonic ultrasound perfusion catheters in each pulmonary artery (PA), (b) PA pressure pre 96/32 (64), (c) Improved pulmonary artery pressure to 47/27 (36) mmHg, day after the EkoSonic + recombinant tissue plasminogen activator catheter Directed Therapy (CDT)
case_images: HV-25-42-g002.jpg
case_images: PMC11104548_01_HV-25-42-g002.jpg
case_images: heartviews.heartviews_103_23-F2
case_images: A PA catheter was placed in the main PA to conduct pulmonary angiography [Figure 1c], and baseline pulmonary artery pressure (PAP) was found to be markedly raised 96/32 (mean 64) mmHg [Figure 2b]. Catheter was used for the left PA through a separate right femoral vein puncture [Figure 2a]. Catheter therapy with a recombinant tissue plasminogen activator (rtPA) 50 mg was given through an EKOS Catheter with multiple delivery ports divided between two catheters, slowly over 16 h along with unfractionated heparin (UFH). A repeat PA measurement on the following day showed a significant 46% reduction in PAP to 47/27 (mean 39) mmHg [Figure 2c].