case_images: PMC2929522_01
case_images: Macrophotograph showing solid tumoral lesion in subepidermal area. A slice of the lesion contained some regions of bleeding.
case_images: CRM2010-913734.001.jpg
case_images: PMC2929522_01_CRM2010-913734.001.jpg
case_images: fig1
case_images: A slice of the lesion contained some regions of bleeding (Figure 1). 
case_images: Histological microphotograph showing neoplastic cells with prominent nucleoli and moderate plemorphism beneath the squamous epithelium (H&E; (a) x100; (b) x200; (c) x400).
case_images: CRM2010-913734.002.jpg
case_images: PMC2929522_01_CRM2010-913734.002.jpg
case_images: fig2
case_images: The lesion was localized predominantly in the dermis, beneath hyperkeratotic epidermis, and pressing on subcutaneous fatty tissue (Figure 2(a)). The tumor cells had translucent cytoplasm, prominent cytoplasmic membranes, and round-to-ovoid nuclei (Figure 2(b)). Pleomorphisms in the tumor cell nuclei and eosinophilic nucleoli were apparent (Figure 2(c)).
case_images: Renal cell carcinoma marker and vimentine immunoreactions in neoplastic tumor cells (ABC-DAB; (a, b) x200).
case_images: CRM2010-913734.003.jpg
case_images: PMC2929522_01_CRM2010-913734.003.jpg
case_images: fig3
case_images: The tumor cells reacted positively with RCC (Figure 3(a)), vimentin (Figure 3(b)), pan-CK, EMA (Figure 4(a)), and CD10, but no reaction was observed with the other immune indicators.
case_images: Diffuse positive membranous immunoreaction with antibodies against EMA (a) and focal positive nuclear Ki-67 immunoreaction (b) are observed in the clear cells (ABC-DAB; (a) x200; (b) x400).
case_images: CRM2010-913734.004.jpg
case_images: PMC2929522_01_CRM2010-913734.004.jpg
case_images: fig4
case_images: The tumor cells reacted positively with RCC (Figure 3(a)), vimentin (Figure 3(b)), pan-CK, EMA (Figure 4(a)), and CD10, but no reaction was observed with the other immune indicators. A 5% Ki67 index was determined for the neoplastic cells (Figure 4(b)).