case_images: PMC8577472_01
case_images: PMC8577472_02
case_images: Flow cytometry plots from the dihydrorhodamine assay. Unstimulated (A) and PMA stimulated (B) neutrophils from a normal control. Patient's neutrophils exhibited the typical CGD XL- carrier bimodal distribution upon PMA stimulation; in 2005, 34% of neutrophils generated normal oxidative activity (C), in 2018, 6% of neutrophils had normal oxidative activity (D).
case_images: gr1.jpg
case_images: PMC8577472_02_gr1.jpg
case_images: fig0005
case_images: The flow cytometric dihydrorhodamine (DHR) assay revealed that only 6% of her neutrophils were able to mount normal oxidative burst, while at the age of 21 years, when her son was diagnosed with CGD, the DHR assay had revealed normal oxidative activity in 34% of her neutrophils (Fig. 1).