case_images: PMC11004277_01
case_images: PMC11004277_02
case_images: Representative diagnostic images at primary diagnosis for case 2. (A) Contrast-enhanced computed tomography of chest abdomen and pelvis showing multiple bilateral, centrally necrotic lung metastases and a singular retroperitoneal para-aortic lymph node metastasis. (B) T2-weighted image of a whole-brain MRI showing a central metastasis close to the pituitary gland, which lead to a clinically significant diabetes mellitus with polyuria and polydipsia.
case_images: fonc-14-1338438-g001.jpg
case_images: PMC11004277_02_fonc-14-1338438-g001.jpg
case_images: f1
case_images: A subsequent CT of thorax, abdomen, and pelvis confirmed the widespread pulmonary metastatic lesions and also showed a large centrally necrotic left-sided retroperitoneal lymph node of 5.3 cm x 4.6 cm adjacent to the pancreatic tail ( Figure 1 ). Consequently, the patient underwent an additional magnetic resonance imaging (MRI) of the brain, which revealed metastases in the left hemisphere with perifocal edema, in the right splenium and at the base of the pituitary gland ( Figure 1 ), the latter causing an additionally diagnosed diabetes insipidus as an explanation for his polydipsia and polyuria of about 10 L/day.