case_images: PMC6662482_01
case_images: PET-CT scan images. (a) Pathologically enlarged, metabolically active left axillary lymph node. (b) Metabolically active thickening and seroma around left breast implant.
case_images: CRIG2019-5647940.001.jpg
case_images: PMC6662482_01_CRIG2019-5647940.001.jpg
case_images: fig1
case_images: PET CT scan confirmed increased uptake in the left axillary node and around the left breast implant (Figure 1), without other evident areas of disease.
case_images: (a) Surgically removed textured silicone implant. (b) Fibrous capsule from which the implant was removed; solid BIA-ALCL deposits on the internal surface; (c) seroma fluid from inside the fibrous capsule which contained CD30-positive atypical lymphocytes.
case_images: CRIG2019-5647940.002.jpg
case_images: PMC6662482_01_CRIG2019-5647940.002.jpg
case_images: fig2
case_images: Surgery was performed with en bloc capsulectomy and removal of the implant (Figure 2).
case_images: (a) H&E axillary lymph node showing ALCL; (b) H&E capsule showing BIA-ALCL; (c) CD30 positive immunohistochemical staining on capsular lymphoma cells.
case_images: CRIG2019-5647940.003.jpg
case_images: PMC6662482_01_CRIG2019-5647940.003.jpg
case_images: fig3
case_images: Histopathological examination (Figure 3) demonstrated both the breast capsule and lymph node to be infiltrated with CD30 positive, ALK-negative BIA-ALCL.
case_images: A: family pedigree. Proband for this case report is family member A. Other cancer-affected relatives: B-D, as described in the article.
case_images: CRIG2019-5647940.004.jpg
case_images: PMC6662482_01_CRIG2019-5647940.004.jpg
case_images: fig4
case_images: The pedigree is shown in Figure 4.