case_images: PMC11412948_01
case_images: Images of the patient vulva at different stage. (A) Physical examination of the patient prior to surgery demonstrated the presence of vulvar swelling. (B) Vulva of the patient, one month after the first resection of the lesion on the left labium minus. (C). Image of the patient vulva, post-second resection of the lesions on the left labium majus and the right side of mons pubis. (D). Follow-up examination for 1-year post-surgery showed no obvious signs of recurrence.
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case_images:   Figure 1A  illustrated the results of the patient's physical examination, which revealed chronic vulvar swelling, involving both labia majora. The initial excision involved the lesion on the left labium minus (illustrated as the green area in the graph above), followed by a second excision after a one-month interval, encompassing the lesions on the left labium majus (indicated by the red area in the diagram) and the right side of the mons pubis, as shown in  Figures 1B, C . Figure 4 . Follow-up examinations for 1-year post-surgery showed no obvious signs of recurrence, as shown in  Figure 1D .
case_images: Multiple dilated lymphatic vessels, with differing lumen sizes and irregular shapes, are present in superficial and deep dermis of a vulvar lesion tissue section, as shown by hematoxylin & eosin (H&E) staining.
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case_images: Pathological examination of the excised specimen revealed multiple dilated lymphatic vessels of varying lumen sizes and irregular shapes in superficial and deep dermis, as illustrated in  Figure 2 .
case_images: Immunohistochemical staining for D2-40, a marker for lymphatic endothelial cells, within the resected vulvar lesion.
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case_images: The lymphatic vessels were delineated by D2-40 staining, a specific marker for lymphatic endothelial cells, as shown in  Figure 3 .
case_images: Lumen of dilated lymphatic vessels within the resected vulvar lesion, depicting the presence of a substantial infiltration of plasma cells and lymphocytes, under H&E staining.
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case_images: Figure 4 . Follow-up examinations for 1-year post-surgery showed no obvious signs of recurrence, as shown in  Figure 1D .
case_images: Historical and current information from this episode of care organized as a imeline.
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case_images: A chronological overview of the complete case is presented on a timeline in  Figure 5 .