case_images: PMC11555608_01
case_images: Two masses were observed in the left armpit with local cutaneous redness.
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case_images: On physical examination, two masses were observed in the left axilla, the larger of which was approximately 3 cm x 1 cm, with local cutaneous redness (Figure 1).
case_images: Postoperative pathology confirmed cutaneous myoepithelial carcinoma with lymph node metastasis. (a) Tumor had trabecular infiltrating growth (200x). (b) Tumor cytoplasm was eosinophilic, nucleoli were prominent, and pathological mitotic figures were easily seen (400x). (c) Intravascular tumor thrombus was observed (400x). (d) Neurological invasion was present (400x). (e) Lymph node was invaded by tumor cells (100x). (f) The morphology of the tumor cells in lymph node was consistent with that of the primary lesion, with eosinophilic cytoplasm and significant nucleoli (200x).
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case_images: A pathological examination revealed trabecular infiltrating growth (Figure 2a), eosinophilic cytoplasm, prominent nucleoli, and mitotic figures visible in the tumor (Figure 2b). Intravascular tumor thrombus and neurological invasion were also found (Figure 2c,d). Metastatic carcinoma 15/17 was also observed in the left axillary lymph node, with the normal structures of the lymph node replaced by tumor cells showing extensive infiltration and growth (Figure 2e). The tumor cells displayed significant nucleoli and eosinophilic cytoplasm similar to the primary lesion (Figure 2f).
case_images: Detection of markers of cutaneous myoepithelial carcinoma by immunochemistry analysis. (a) Positive expression of cytokeratin (200x). (b) Positive expression of SMA (200x). SMA, smooth muscle actin.
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case_images: Furthermore, the tumor cells were positive for expression of cytokeratin and SMA (Figure 3).