case_images: PMC10901191_01
case_images: Flow cytometry was performed on the bone marrow aspirate revealing a flow differential of 61.8% lymphocytes, 4.6% monocytes, 15.1% granulocytes, 15.9% CD45 dim (blasts), 2.9% CD45 negative, 0.4% plasma cells, and 8.4% CD34+. Gating on the lymphocyte population reveals predominantly T lymphocytes present with no kappa or lambda light chain restriction and no aberrant markers noted. SS INT LIN: side scatter intensity, linear; CD45 KO: CD45 knockout cells
case_images: cureus-0016-00000053159-i01.jpg
case_images: PMC10901191_01_cureus-0016-00000053159-i01.jpg
case_images: FIG1
case_images: Flow cytometry was performed on the bone marrow aspirate and was fairly unremarkable (Figure 1).
case_images: Fluorescence in situ hybridization (FISH) analysis using 7q-/-7 tri: The probe set for chromosome 7 shows an abnormal FISH signal pattern of 1R1G1A indicative of monosomy 7
case_images: cureus-0016-00000053159-i02.jpg
case_images: PMC10901191_01_cureus-0016-00000053159-i02.jpg
case_images: FIG2
case_images: MDS fluorescence in situ hybridization (FISH) was performed and revealed that all cells analyzed showed a loss of one copy of chromosome 7 (Figure 2).
case_images: Cytogenetic analysis shows an abnormal female karyotype. All cells analyzed show a loss of one copy of chromosome 7
case_images: cureus-0016-00000053159-i03.jpg
case_images: PMC10901191_01_cureus-0016-00000053159-i03.jpg
case_images: FIG3
case_images: Cytogenetics final analysis confirmed Karyotype 45, XX,-7(20) (Figure 3).