case_images: PMC11831057_01
case_images: Endoscopic images of the duodenum.
case_images: bcr-18-2-g001.jpg
case_images: PMC11831057_01_bcr-18-2-g001.jpg
case_images: F1
case_images: Serology for CD was strongly positive, prompting an upper gastrointestinal tract endoscopy, which revealed normal examination till the second part of the duodenum (figure 1).
case_images: Low-power view of multiple duodenal biopsies showing an area of total villous atrophy (red arrow) and an area with significant villous shortening (black arrow).
case_images: bcr-18-2-g002.jpg
case_images: PMC11831057_01_bcr-18-2-g002.jpg
case_images: F2
case_images: Histological evaluation confirmed the diagnosis of CD, with findings consistent with Marsh type 3, Corazza: grade B1, showing hypertrophic crypts and partial to subtotal loss of villi (figures2  3).
case_images: Heavy lymphocyte infiltration of the enterocytes, highlighted by H&E staining (A) and CD3 immunostaining (B).
case_images: bcr-18-2-g003.jpg
case_images: PMC11831057_01_bcr-18-2-g003.jpg
case_images: F3
case_images: Histological evaluation confirmed the diagnosis of CD, with findings consistent with Marsh type 3, Corazza: grade B1, showing hypertrophic crypts and partial to subtotal loss of villi (figures2  3).