case_images: PMC10352934_01
case_images: Poorly cohesive adenocarcinoma (yellow arrows) admixed with abundant tumor-infiltrating lymphocytes (red arrows) in subperitoneal connective tissue (scale 50 mum).
case_images: cro-2023-0016-0001-530965_F01.jpg
case_images: PMC10352934_01_cro-2023-0016-0001-530965_F01.jpg
case_images: F1
case_images: She underwent an upper endoscopy with a biopsy finding of a poorly cohesive gastric adenocarcinoma and strong immune infiltration, as shown in Figure 1.
case_images: Preserved expression of mismatch repair proteins (MLH1, PMS2, MSH2, MSH6) on immunohistochemistry. MHL1 (a); PMS2 (b); MSH2 (c), and MSH6 (d) (scale 50 mum).
case_images: cro-2023-0016-0001-530965_F02.jpg
case_images: PMC10352934_01_cro-2023-0016-0001-530965_F02.jpg
case_images: F2
case_images: Pathology reported a poorly cohesive, poorly differentiated carcinoma with a preserved expression of mismatch repair proteins on immunohistochemistry, as shown in Figure 2.
case_images: Comparison of the patients' imaging studies (computerized topographies) from December 2020 prior to immunotherapy and January 2023 with immunotherapy (created with BioRender.com).
case_images: cro-2023-0016-0001-530965_F03.jpg
case_images: PMC10352934_01_cro-2023-0016-0001-530965_F03.jpg
case_images: F3
case_images: The patient achieved complete clinical response in January 2023 and remains in complete remission until the present day (more than 1 year and 6 months), as shown in Figure 3.