case_images: PMC7728113_01
case_images: Intraprocedural image of a voluminous pedunculated polyp, with irregular surface tubulo-villous appearance; SFI mode. SFI: Spectral focused imaging
case_images: RJME-61-1-235-fig1.jpg
case_images: PMC7728113_01_RJME-61-1-235-fig1.jpg
case_images: F1
case_images: The lesion responsible for the bleeding was a voluminous pedunculated polyp (2.5/1.5/1.5 cm, a pedicle of 0.8 cm diameter), with hemorrhagic regions, located in the sigmoid (Figure 1).
case_images: Colonic adenoma with low-grade dysplasia. HE staining, x40
case_images: RJME-61-1-235-fig2.jpg
case_images: PMC7728113_01_RJME-61-1-235-fig2.jpg
case_images: F2
case_images: Histologically, the excised fragment was identified as a tubulovillous adenoma with low-grade dysplasia, comprising multiple foci of complete and incomplete squamous metaplasia, similar to squamous morules commonly found in some endometrial carcinomas, as it can be seen in Figures 2,3,4,5,6,7.
case_images: Immunoexpression of p16 in the areas of squamous metaplasia. IHC staining, DAB chromogen, x100. IHC: Immunohistochemical; DAB: 3,3'-Diaminobenzidine
case_images: RJME-61-1-235-fig8.jpg
case_images: PMC7728113_01_RJME-61-1-235-fig8.jpg
case_images: F8
case_images: Ki67 was negative in the areas of squamous metaplasia, suggesting that those areas are mitotically inactive (Figures 8 and 9).
case_images: Absence of Ki67 immunoexpression in the areas of squamous metaplasia. IHC staining, DAB chromogen, x100. IHC: Immunohistochemical; DAB: 3,3'-Diaminobenzidine
case_images: RJME-61-1-235-fig9.jpg
case_images: PMC7728113_01_RJME-61-1-235-fig9.jpg
case_images: F9
case_images: Ki67 was negative in the areas of squamous metaplasia, suggesting that those areas are mitotically inactive (Figures 8 and 9).