case_images: PMC5813913_01
case_images: Endoscopic picture of ulcers at the soft palate and gingiva with irregular margins, raised edges and erythematous floors.
case_images: can-12-801fig1.jpg
case_images: PMC5813913_01_can-12-801fig1.jpg
case_images: figure1
case_images: A screening upper endoscopy with narrow band imaging (NBI) showed multiple oral and pharyngeal ulcers with irregular margins, raised edges and erythematous floors (Figures 1 and 2), thick aryepiglottic folds (Figure 3), multiple small gastric fundic gland polyps and multiple small submucosal duodenal swellings (Figure 4).
case_images: Ulcer at the uvula with white light endoscopy (left) and NBI (right).
case_images: can-12-801fig2.jpg
case_images: PMC5813913_01_can-12-801fig2.jpg
case_images: figure2
case_images: A screening upper endoscopy with narrow band imaging (NBI) showed multiple oral and pharyngeal ulcers with irregular margins, raised edges and erythematous floors (Figures 1 and 2), thick aryepiglottic folds (Figure 3), multiple small gastric fundic gland polyps and multiple small submucosal duodenal swellings (Figure 4).
case_images: Thickened aryepiglottic fold (yellow arrow) suspicious of infiltration.
case_images: can-12-801fig3.jpg
case_images: PMC5813913_01_can-12-801fig3.jpg
case_images: figure3
case_images: A screening upper endoscopy with narrow band imaging (NBI) showed multiple oral and pharyngeal ulcers with irregular margins, raised edges and erythematous floors (Figures 1 and 2), thick aryepiglottic folds (Figure 3), multiple small gastric fundic gland polyps and multiple small submucosal duodenal swellings (Figure 4).
case_images: Multiple submucosal swellings at the second part of the duodenum as seen by white light endoscopy (upper left), NBI (lower left) and magnified view (right).
case_images: can-12-801fig4.jpg
case_images: PMC5813913_01_can-12-801fig4.jpg
case_images: figure4
case_images: A screening upper endoscopy with narrow band imaging (NBI) showed multiple oral and pharyngeal ulcers with irregular margins, raised edges and erythematous floors (Figures 1 and 2), thick aryepiglottic folds (Figure 3), multiple small gastric fundic gland polyps and multiple small submucosal duodenal swellings (Figure 4).
case_images: Histopathologic sections from oropharyngeal mucosa, stained by hematoxylin & eosin with different magnification powers (x4: left side, x8: right side); showing malignant lymphocytic infiltration with hyperchromatic enlarged nuclei and scanty cytoplasm.
case_images: can-12-801fig5.jpg
case_images: PMC5813913_01_can-12-801fig5.jpg
case_images: figure5
case_images: Histopathologic examination of pharyngeal biopsy revealed infiltration by malignant lymphoid cells with hyperchromatic enlarged nuclei and scanty cytoplasm (Figures 5 and 6) while immune-histochemical staining showed CD3 (+), CD4 (+) and CD8 (-) cells (Figures 7-9).
case_images: Histopathologic sections stained by hematoxylin & eosin from the same specimen with higher magnification powers (x20: left side, x40: right side).
case_images: can-12-801fig6.jpg
case_images: PMC5813913_01_can-12-801fig6.jpg
case_images: figure6
case_images: Histopathologic examination of pharyngeal biopsy revealed infiltration by malignant lymphoid cells with hyperchromatic enlarged nuclei and scanty cytoplasm (Figures 5 and 6) while immune-histochemical staining showed CD3 (+), CD4 (+) and CD8 (-) cells (Figures 7-9).
case_images: Immune-histochemical staining of the same sections showing CD3-positive cells (x20: left side, x40: right side).
case_images: can-12-801fig7.jpg
case_images: PMC5813913_01_can-12-801fig7.jpg
case_images: figure7
case_images: Histopathologic examination of pharyngeal biopsy revealed infiltration by malignant lymphoid cells with hyperchromatic enlarged nuclei and scanty cytoplasm (Figures 5 and 6) while immune-histochemical staining showed CD3 (+), CD4 (+) and CD8 (-) cells (Figures 7-9).
case_images: Immune-histochemical staining of the same sections showing CD4-positive cells (x20: left side, x40: right side).
case_images: can-12-801fig8.jpg
case_images: PMC5813913_01_can-12-801fig8.jpg
case_images: figure8
case_images: Histopathologic examination of pharyngeal biopsy revealed infiltration by malignant lymphoid cells with hyperchromatic enlarged nuclei and scanty cytoplasm (Figures 5 and 6) while immune-histochemical staining showed CD3 (+), CD4 (+) and CD8 (-) cells (Figures 7-9).
case_images: Immune-histochemical staining of the same sections showing CD8-negative cells (x20: left side, x40: right side).
case_images: can-12-801fig9.jpg
case_images: PMC5813913_01_can-12-801fig9.jpg
case_images: figure9
case_images: Histopathologic examination of pharyngeal biopsy revealed infiltration by malignant lymphoid cells with hyperchromatic enlarged nuclei and scanty cytoplasm (Figures 5 and 6) while immune-histochemical staining showed CD3 (+), CD4 (+) and CD8 (-) cells (Figures 7-9).