case_images: PMC10601771_01
case_images: PMC10601771_02
case_images: PMC10601771_03
case_images: Family lineage with age of identification of MTC and age at the last follow-up. Proband - a boy in left lower angle (matched by pointer). Green - cases of revealed MTC after preventive TE in asymptomatic patients. Blue - patients with preoperative evidence of MTC.
case_images: cro-2023-0016-0001-533570_F01.jpg
case_images: PMC10601771_03_cro-2023-0016-0001-533570_F01.jpg
case_images: F1
case_images: Preventive TE was performed on the native sister of the proband at the age of 3 years old as well, and MTC was also revealed (Fig. 1).
case_images: PMC10601771_04
case_images: Trocars position in TOETVA.
case_images: cro-2023-0016-0001-533570_F02.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F02.jpg
case_images: F2
case_images: The approach was done by one 10 mm and two 5 mm ports (Fig. 2).
case_images: Identification of parathyroid glands and recurrence laryngeal nerve.
case_images: cro-2023-0016-0001-533570_F03.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F03.jpg
case_images: F3
case_images: Vessels were crossed as close as possible to TG and parathyroid glands were identified and preserved (Fig. 3).
case_images: Patient's view before operation (left), the next day after operation (in center), and 1 month later (right).
case_images: cro-2023-0016-0001-533570_F04.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F04.jpg
case_images: F4
case_images: Only transitory paresthesia and slight edema of submental compartment were noticed, which were resolved independently in 4 weeks (Fig. 4, 5).
case_images: Mucosa of mouth vestibule 1 month after operation.
case_images: cro-2023-0016-0001-533570_F05.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F05.jpg
case_images: F5
case_images: Only transitory paresthesia and slight edema of submental compartment were noticed, which were resolved independently in 4 weeks (Fig. 4, 5).
case_images: Nonencapsulated medullary thyroid cancer.
case_images: cro-2023-0016-0001-533570_F06.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F06.jpg
case_images: F6
case_images: An immunohistochemical study was performed with antibodies to calcitonin and diffuse bright cytoplasmic expression of calcitonin was detected (Fig. 6, 7).
case_images: Expression of calcitonin in tumor cells.
case_images: cro-2023-0016-0001-533570_F07.jpg
case_images: PMC10601771_04_cro-2023-0016-0001-533570_F07.jpg
case_images: F7
case_images: An immunohistochemical study was performed with antibodies to calcitonin and diffuse bright cytoplasmic expression of calcitonin was detected (Fig. 6, 7).