case_images: PMC3439720_01
case_images: Overview of EVA with the six exome mining modules. To store and manage variation data, EVA consist of a database, ExomeDB and a friendly web interface. To date six modules permitted to authentify the user (1), to integrate data (2), to search and browse data with charts (3) or tables (4,5) and finally to conduct a customizable filtering strategy (6) by a combination of selected criteria dealing with common variations, molecular types of variants, inheritance modes and multiple samples intersection or difference.
case_images: 1471-2105-13-S14-S9-1.jpg
case_images: PMC3439720_01_1471-2105-13-S14-S9-1.jpg
case_images: F1
case_images: Figure 1 corresponds to the raw 'variation overview' of this exome project integrated in EVA and is obtained with the Table browser module.
case_images: Examples of graphical visualization with the Variation statistics module of EVA. Through a guided mode selection (a), the distribution of variations for the 14 ADEOAD exome project are graphically represented by a caryotype view (b), a bar chart or a pie chart distribution (c, d). Useful analysis of indels (e), ratio of transition (purine/purine or pyrimidine/pyrimidine) substitutions to transversion (purine/pyrimidine) substitutions (f) and substitution matrix of amino-acid (not showed) are proposed.
case_images: 1471-2105-13-S14-S9-2.jpg
case_images: PMC3439720_01_1471-2105-13-S14-S9-2.jpg
case_images: F2