case_images: PMC5488594_01
case_images: Chest computed tomography scan image show the right lower lobe nodule of the lung
case_images: CJ-14-15-g001.jpg
case_images: PMC5488594_01_CJ-14-15-g001.jpg
case_images: F1
case_images: Chest CT-scan showed a 1.8 cm x 0.9 cm nodule in the right lower lung lobe [Figure 1]. The chest CT scan showed a 1.8 cm x 0.9 cm nodule in the right lower lung lobe [Figure 1].
case_images: (a) Papanicolaou stain smears show high grade spindle cell neoplasm. (b) H and E stained section from cell block shows sweeping fascicles of spindle cell lesion with nuclear atypia. (c) Cell block; prostatic specific antigen immunostains highlighted the large atypical epithelial cells. (d) Cell block; cytokeratin adverse event 1/3 immunostains is negative in the large atypical stromal cells. (e) Prostatectomy resection; left lobe shows prostatic stromal sarcoma. (f) Prostatectomy specimen; right lobe, prostatic adenocarcinoma, acinar, type, Gleason score 3 + 3 = 6. (g) Neoplastic spindle cells on cytology. (h) Cytomorphology showing high grade spindle cells
case_images: CJ-14-15-g002.jpg
case_images: PMC5488594_01_CJ-14-15-g002.jpg
case_images: F2
case_images: The biopsy showed malignant neoplasm with mixed spindle and epithelial cell features confirmed to be metastatic PSS with proper immunohistochemical stains [Figure 2a-d]. The morphologic picture and the immunohistochemical profile of the PSS are identical to the lung nodular lesion [Figure 2e and f]. The cells had a fascicular arrangement with focal storiform pattern with no glandular architectures were identified [Figure 2a, b, g and h]. The current case tumor cells were positive for CK AE1/AE3, PSA, PR, CD34, actin, desmin and vimentin, and negative for S100, TTF-1, napsin A, CK 7, CD117, ER, and melan A [Figure 2c and d].