case_images: PMC6945939_01
case_images: Echocardiographic images of cardiac rhabdomyomas from parasternal long-axis (left column), parasternal short-axis (middle column), and apical 5-chamber (right column) views. The top row of images was taken on the day of birth. The middle row of images was taken on the 13th day after birth. The bottom row of images was taken at 43 days after initiating sirolimus. LA, left atrium; LV, left ventricle; RV, right ventricle; AO, aorta; arrows, subaortic mass.
case_images: bmh-0002-0001-g01.jpg
case_images: PMC6945939_01_bmh-0002-0001-g01.jpg
case_images: F1
case_images: On the day of birth, echocardiogram revealed rhabdomyomas of various sizes with multiple locations, including a huge 13.2-mm rhabdomyoma located in the left ventricle (LV) free wall to interventricular septum, a 4.9 x 3.3-mm subaortic interventricular septum, and a 5.1-mm rhabdomyoma in the LV free wall and the right ventricle (RV) apex area (Fig. 1). The LV function by M-mode echocardiography was decreased due to dyskinetic hypertrophied interventricular septum to the LV free wall (Fig. 1). The interventricular septal mass became smaller (8.7 mm) and nearly lost its echogenicity at 43 days after mTOR treatment (Fig. 1).
case_images: During sirolimus treatment, serum levels of sirolimus and white blood cell (WBC) counts were monitored at neonatal intensive care unit admission.
case_images: bmh-0002-0001-g02.jpg
case_images: PMC6945939_01_bmh-0002-0001-g02.jpg
case_images: F2
case_images: The results are shown in Figure 2.