case_images: PMC11150800_01
case_images: Contrast-enhanced computed tomography on admission. Contrast-enhanced computed tomography showing left upper lobe lung cancer (arrowheads).
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case_images: PMC11150800_01_fendo-15-1407192-g001.jpg
case_images: f1
case_images: C-peptide level was 0.42 ng/mL, and the GAD antibody level exceeded 2000 U/mL. Chest radiography and computed tomography ( Figure 1 ) confirmed known lung cancer, with no additional findings.
case_images: Clinical course. On the 48th day after the start of immunotherapy, the blood glucose level spiked; thereafter, the blood glucose levels fluctuated. The HbA1c and C-peptide levels increased and decreased rapidly, respectively. Continuous intravenous insulin was administered at 0.2 to 5.0 U/h from day 48 to day 50. FBS, fasting blood sugar; HbA1c, glycated hemoglobin; Ipi, ipilimumab; nivolumab, nivolumab.
case_images: fendo-15-1407192-g002.jpg
case_images: PMC11150800_01_fendo-15-1407192-g002.jpg
case_images: f2
case_images: The clinical course of the patient is summarized in  Figure 2 .