case_images: PMC10849904_01
case_images: (a-c) Rapidly progressive painful ulcer (d) Positive pathergy test.
case_images: JIR-17-687-g0001.jpg
case_images: PMC10849904_01_JIR-17-687-g0001.jpg
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case_images: Physical examination revealed deep ulcers with irregular, violaceous and undermined borders on his bilateral cheek and upper lip (Figure 1a and b). Multiple irregular, violaceous lesions with central ulcer and undermined elevated borders had developed on his bilateral cheek and upper lip (Figure 1c).  During hospital, cutaneous papulopustule developed on his opisthenar at an intravenous cannula site, suggesting positive pathergy test (Figure 1d).
case_images: Histological HE staining photographs. (a) magnified 5 times, and (b) magnified 20 times.
case_images: JIR-17-687-g0002.jpg
case_images: PMC10849904_01_JIR-17-687-g0002.jpg
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case_images: A skin biopsy of the facial ulcer revealed an intense neutrophilic infiltrate, neutrophilic pustules and abscess formation (Figure 2).
case_images: Clinical photos of 7 months after treatment.
case_images: JIR-17-687-g0003.jpg
case_images: PMC10849904_01_JIR-17-687-g0003.jpg
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case_images: After a 7-month follow-up, the patient's skin lesions have healed well and there are no signs of recurrence (Figure 3).