case_images: PMC4065452_01
case_images: Tumor extending from distal aspect of 37 to uvula
case_images: JOMFP-18-77-g001.jpg
case_images: PMC4065452_01_JOMFP-18-77-g001.jpg
case_images: F1
case_images: Intraorally there was a pedunculated and ulcerated growth covered with slough, extending from the distal aspect of 37 to uvula, measuring approximately 5 x 3 cm [Figure 1].
case_images: Photomicrograph showing epithelial component around the glandular spaces and arranged in solid nests surrounded by spindle component. (H&E stain, x400)
case_images: JOMFP-18-77-g002.jpg
case_images: PMC4065452_01_JOMFP-18-77-g002.jpg
case_images: F2
case_images: These were surrounded by sheets of spindle cells with marked atypical nuclei [Figure 2].
case_images: Immunohistochemistry revealed strong nuclear positivity of tumor cells for Transducer-like enhancer of split 1 (TLE1) in both spindle and epithelial component (IHC stain, x100)
case_images: JOMFP-18-77-g003.jpg
case_images: PMC4065452_01_JOMFP-18-77-g003.jpg
case_images: F3
case_images: Immunohistochemistry revealed strong nuclear positivity in both the components for transducer-like enhancer of split 1 (TLE1) [Figure 3], epithelial membrane antigen (EMA) positivity [Figure 4] in the cuboidal epitheloid cells, vimentin [Figure 5] and Bcl-2 positivity [Figure 6] in the spindle cells, which confirmed the diagnosis of biphasic SS (BSS).
case_images: Immunohistochemistry revealing Epithelial Membrane Antigen (EMA) positivity in the cuboidal epitheloid cells and negativity in the spindle cells (IHC stain, x100)
case_images: JOMFP-18-77-g004.jpg
case_images: PMC4065452_01_JOMFP-18-77-g004.jpg
case_images: F4
case_images: Immunohistochemistry revealed strong nuclear positivity in both the components for transducer-like enhancer of split 1 (TLE1) [Figure 3], epithelial membrane antigen (EMA) positivity [Figure 4] in the cuboidal epitheloid cells, vimentin [Figure 5] and Bcl-2 positivity [Figure 6] in the spindle cells, which confirmed the diagnosis of biphasic SS (BSS).
case_images: Immunohistochemistry revealing vimentin positivity in the spindle cells and negativity in the cuboidal cells (IHC stain, x400)
case_images: JOMFP-18-77-g005.jpg
case_images: PMC4065452_01_JOMFP-18-77-g005.jpg
case_images: F5
case_images: Immunohistochemistry revealed strong nuclear positivity in both the components for transducer-like enhancer of split 1 (TLE1) [Figure 3], epithelial membrane antigen (EMA) positivity [Figure 4] in the cuboidal epitheloid cells, vimentin [Figure 5] and Bcl-2 positivity [Figure 6] in the spindle cells, which confirmed the diagnosis of biphasic SS (BSS).
case_images: Immunohistochemistry revealing Bcl-2 positivity in the spindle cells (IHC stain, x100)
case_images: JOMFP-18-77-g006.jpg
case_images: PMC4065452_01_JOMFP-18-77-g006.jpg
case_images: F6
case_images: Immunohistochemistry revealed strong nuclear positivity in both the components for transducer-like enhancer of split 1 (TLE1) [Figure 3], epithelial membrane antigen (EMA) positivity [Figure 4] in the cuboidal epitheloid cells, vimentin [Figure 5] and Bcl-2 positivity [Figure 6] in the spindle cells, which confirmed the diagnosis of biphasic SS (BSS).