case_images: PMC11125376_01
case_images: Multiple erythematous plaques with thick rough squama on trunk, back, both arms and legs of the patient.
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case_images: NarraJ-4-e207-F1
case_images: Dermatological examination showed that the lesions were multiple erythematous plaques with thick rough squama on trunk, on the back, as well as both arms and legs (Figure 1).
case_images: Psoriasiform lesion showing clubbed-shaped of the rete ridges, parakeratosis, hyperkeratosis, acanthosis, dilated capillary and infiltration of neutrophils into stratum corneum (Munro microabscess) and stratum spinosum (spongiform pustule of Kogoj) (hematoxylin-eosin staining, 100 x magnification).
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case_images: NarraJ-4-e207-F2
case_images: Histopathological examination revealed that there were hyperkeratosis, parakeratosis and Munro microabscess in the stratum corneum, as well as hypogranulosis and spongiform pustule of Kogoj (Figure 2).
case_images: Follow up of the lesions after 5 weeks of secukinumab administration. Multiple plaques with squama on trunk, back, arms and legs of the patient. The erythematous plaques have decreased. There were improvements of the patient's condition.
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case_images: PMC11125376_01_NarraJ-4-e207-g003.jpg
case_images: NarraJ-4-e207-F3
case_images: The lesions then began to disappear and the joint pain symptoms began to decrease (Figure 3).