case_images: PMC5050589_01
case_images: Anterior view of patient s face and body
case_images: 13039_2016_278_Fig1_HTML.jpg
case_images: PMC5050589_01_13039_2016_278_Fig1_HTML.jpg
case_images: Fig1
case_images: A 4-year-old male proband (Figs. 1, 2, 3) presented with global developmental delay noticed by his family when he was around 11 months of age.
case_images: Lateral view of patient s face and body
case_images: 13039_2016_278_Fig2_HTML.jpg
case_images: PMC5050589_01_13039_2016_278_Fig2_HTML.jpg
case_images: Fig2
case_images: A 4-year-old male proband (Figs. 1, 2, 3) presented with global developmental delay noticed by his family when he was around 11 months of age.
case_images: Anterior view of patient s face and body
case_images: 13039_2016_278_Fig3_HTML.jpg
case_images: PMC5050589_01_13039_2016_278_Fig3_HTML.jpg
case_images: Fig3
case_images: A 4-year-old male proband (Figs. 1, 2, 3) presented with global developmental delay noticed by his family when he was around 11 months of age.
case_images: PMC5050589_02
case_images: Brain MRI - Increased signal in T2-weighted images in the withe matter territories adjacent to the lateral ventricles bodies and subcortical zone
case_images: 13039_2016_278_Fig4_HTML.jpg
case_images: PMC5050589_02_13039_2016_278_Fig4_HTML.jpg
case_images: Fig4
case_images: However, we identified sparse increased signal in FLAIR and T2-weighted images in the white matter territories adjacent to the lateral ventricles bodies and subcortical zones (Figs. 4, 5, 6, 7).
case_images: Brain MRI - Increased signal in FLAIR images in the withe matter territories adjacent to the lateral ventricles bodies and subcortical zone
case_images: 13039_2016_278_Fig5_HTML.jpg
case_images: PMC5050589_02_13039_2016_278_Fig5_HTML.jpg
case_images: Fig5
case_images: However, we identified sparse increased signal in FLAIR and T2-weighted images in the white matter territories adjacent to the lateral ventricles bodies and subcortical zones (Figs. 4, 5, 6, 7).
case_images: Brain MRI - Increased signal in FLAIR images in the withe matter territories adjacent to the lateral ventricles bodies and subcortical zone
case_images: 13039_2016_278_Fig6_HTML.jpg
case_images: PMC5050589_02_13039_2016_278_Fig6_HTML.jpg
case_images: Fig6
case_images: However, we identified sparse increased signal in FLAIR and T2-weighted images in the white matter territories adjacent to the lateral ventricles bodies and subcortical zones (Figs. 4, 5, 6, 7).
case_images: Brain MRI - Increased signal in FLAIR images in the withe matter territories adjacent to the lateral ventricles bodies and subcortical zone
case_images: 13039_2016_278_Fig7_HTML.jpg
case_images: PMC5050589_02_13039_2016_278_Fig7_HTML.jpg
case_images: Fig7
case_images: However, we identified sparse increased signal in FLAIR and T2-weighted images in the white matter territories adjacent to the lateral ventricles bodies and subcortical zones (Figs. 4, 5, 6, 7).
case_images: EEG showing non specific slow background activity, as well as no epileptiform discharges
case_images: 13039_2016_278_Fig8_HTML.jpg
case_images: PMC5050589_02_13039_2016_278_Fig8_HTML.jpg
case_images: Fig8
case_images: In addition, around the same period of time, a v-EEG demonstrated signs of a non-specific slow background, but no other abnormal electrographic activity had been identified (Fig. 8).     