case_images: PMC10589024_01
case_images: Computerized tomography (CT) scan of the abdomen with contrast showed a large infiltrative heterogeneous mass (red arrow) involvng the entire right hepatic lobe with a non-occlusive thrombus extending to the portal vein (green arrow).
case_images: jchim-13-04-049f1.jpg
case_images: PMC10589024_01_jchim-13-04-049f1.jpg
case_images: f1-jchim-13-04-049
case_images: Serum AFP was elevated at 1955.8 ng/mL and a CT scan of the abdomen and pelvis demonstrated a large infiltrative heterogeneous mass involving the entire right hepatic lobe with a non-occlusive thrombus extending to the portal vein (Fig. 1).
case_images: Immunohistochemical study shows positive CA 19-9 stain of adenocarcinoma.
case_images: jchim-13-04-049f2.jpg
case_images: PMC10589024_01_jchim-13-04-049f2.jpg
case_images: f2-jchim-13-04-049
case_images: Ultrasound-guided liver biopsy and immunohistochemical analysis demonstrated positive expression for cytokeratin 20, and CA 19-9 (Fig. 2).
case_images: Histology of poorly differentiated adenocarcinoma composed of duct-like structure with high pleomorphism. H&E 400x.
case_images: jchim-13-04-049f3.jpg
case_images: PMC10589024_01_jchim-13-04-049f3.jpg
case_images: f3-jchim-13-04-049
case_images: The histological pattern was consistent with poorly differentiated adenocarcinoma (Fig. 3), most likely pancreaticobiliary in origin consistent with ICC.