case_images: PMC6815603_01
case_images: Macroscopic and microscopic descriptions of WD in case number 1. (a) Intestinal lipodystrophy in duodenum. (b) CD68 positive for macrophage-duodenal biopsy. (c) PAS-positive granules-duodenal biopsy.
case_images: CRIRH2019-3410468.001.jpg
case_images: PMC6815603_01_CRIRH2019-3410468.001.jpg
case_images: fig1
case_images: The histological findings resulted in PAS-positive granules in macrophages (intestinal lipodystrophy) (Figure 1).
case_images: Course of body temperature ( C) in case number 1.
case_images: CRIRH2019-3410468.002.jpg
case_images: PMC6815603_01_CRIRH2019-3410468.002.jpg
case_images: fig2
case_images: There were no relapses after 6 months and was a significant weight recovery (Figures 2 and 3).
case_images: Course of CRP (mg/l) in case number 1.
case_images: CRIRH2019-3410468.003.jpg
case_images: PMC6815603_01_CRIRH2019-3410468.003.jpg
case_images: fig3
case_images: There were no relapses after 6 months and was a significant weight recovery (Figures 2 and 3).
case_images: PMC6815603_02
case_images: Course of CRP (mg/l) in case number 2.
case_images: CRIRH2019-3410468.004.jpg
case_images: PMC6815603_02_CRIRH2019-3410468.004.jpg
case_images: fig4
case_images: Tropheryma whipplei detection by PCR on saliva and stool in case number 2 (original report from the Reference Laboratory of Marseille, France).
case_images: CRIRH2019-3410468.005.jpg
case_images: PMC6815603_02_CRIRH2019-3410468.005.jpg
case_images: fig5
case_images: Thus, the duodenal samples, as well as other samples from stool and saliva, collected before the introduction of the antibiotic therapy, were analyzed for T. whipplei by PCR in the Reference Center of Marseille, resulting all positive (Figures 5 and 6).
case_images: Tropheryma whipplei detection by PCR on duodenum sample in case number 2 (duplicate from the original report from the Reference Laboratory of Marseille, France).
case_images: CRIRH2019-3410468.006.jpg
case_images: PMC6815603_02_CRIRH2019-3410468.006.jpg
case_images: fig6
case_images: Thus, the duodenal samples, as well as other samples from stool and saliva, collected before the introduction of the antibiotic therapy, were analyzed for T. whipplei by PCR in the Reference Center of Marseille, resulting all positive (Figures 5 and 6).