case_images: PMC10073570_01
case_images: Necropsy findings in rabbit #4 (Oryctolagus cuniculus cuniculus) case. Liver with an enlarged, pale, and distinct lobular pattern with light gray discoloration in the edges of the lobes (likely a postmortem change) (A). Lungs (B) and uterus (C) had multifocal to coalescing hemorrhages.
case_images: fvets-10-1144227-g0001.jpg
case_images: PMC10073570_01_fvets-10-1144227-g0001.jpg
case_images: F1
case_images: At necropsy, the liver had an enlarged, pale, and distinct lobular pattern with regional areas of light gray discoloration in the edges of all lobes (likely a postmortem change) (Figure 1A). Additionally, the lungs (Figure 1B) and uterus (Figure 1C) had multifocal to coalescing hemorrhages.
case_images: Liver with a severe generalized hepatocellular necrosis with hemorrhage, most evident in the periportal areas, H&E stain (A). Liver, detail of necrotic cells, H&E [(A) inset]. Liver. Marked hepatocytes' immunolabeling with monoclonal antibody (Mab) against rabbit hemorrhagic disease virus capsid proteins (B).
case_images: fvets-10-1144227-g0002.jpg
case_images: PMC10073570_01_fvets-10-1144227-g0002.jpg
case_images: F2
case_images: Hepatocellular necrosis with hemorrhage was detected in all sections examined (Figure 2A), generally with a random distribution, although more evident in the periportal areas. Figure 2B depicts the hepatocytes' positive staining with the immunohistochemical technique, confirming the presence of RHDV.