case_images: PMC11707780_01
case_images: Lung biopsy specimen. Histologic assessment of the lung biopsy shows a trabecular and nested arrangement of tumor cells with basal palisading and central stellate reticulum, diagnostic of metastatic ameloblastoma. Some areas with squamous, follicular, and granular cell changes are also seen. (H&E, 100x).
case_images: 10.1177_20363613241309961-fig1.jpg
case_images: PMC11707780_01_10.1177_20363613241309961-fig1.jpg
case_images: fig1-20363613241309961
case_images: This was followed by a lung biopsy which revealed ameloblastoma (Figure 1).
case_images: Metastatic lung disease regression from prior to starting copanilisib (left image) to the most recent imaging from June 2024 (right image).
case_images: 10.1177_20363613241309961-fig2.jpg
case_images: PMC11707780_01_10.1177_20363613241309961-fig2.jpg
case_images: fig2-20363613241309961
case_images: Since beginning therapy with copanlisib, she has experienced notable disease regression with a partial response per the Response Evaluation Criteria in Solid Tumors (RECIST) (v1.1) Criteria (Figure 2).