case_images: PMC7098359_01
case_images: Multimodal imaging of multiple vitelliform lesions in a patient with Alport syndrome. Scanning laser ophthalmoscopy of the right (a) and left (b) eye shows multiple yellowish lesions along the superior vascular arcades, in the temporal maculae, and nasally to the optic discs. Autofluorescence images of the right (c) and left (d) eye display hyperautofluorescence corresponding to the lesions. eSpectral-domain optical coherence tomography of the left macula reveals temporal disruption of the retinal pigment epithelium and hyperreflective subretinal material surrounded by a localized retinoschisis. There is also an irregular foveal contour.
case_images: cop-0011-0079-g01.jpg
case_images: PMC7098359_01_cop-0011-0079-g01.jpg
case_images: F1
case_images: Bilateral dilated fundus evaluation revealed multiple yellowish lesions of differing sizes located along the superior vascular arcades, nasally to the optic discs, and in the temporal macular regions; the largest lesion constituted two-thirds of an optic disc diameter (Fig. 1a, b). Fundus autofluorescence imaging exposed hyperautofluorescence corresponding to the yellow lesions (Fig. 1c, d). Macular SD-OCT displayed multilayered retinoschisis located in the superotemporal macula of the left eye (Fig. 1e).
case_images: Macular spectral-domain optical coherence tomography in a patient with Alport syndrome. In both the right (a) and the left (b) eye, there is central macular thinning and an irregular foveal contour.
case_images: cop-0011-0079-g02.jpg
case_images: PMC7098359_01_cop-0011-0079-g02.jpg
case_images: F2
case_images: Furthermore, central macular thinning and an irregular foveal contour were evident in both eyes (Fig. 2).