case_images: PMC3420629_01
case_images: MEP magnitude was determined by identifying the peak-to-peak amplitude of the quadriceps EMG trace following each TMS-evoked stimulus.
case_images: CRIM.RHEUMATOLOGY2011-537420.001.jpg
case_images: PMC3420629_01_CRIM.RHEUMATOLOGY2011-537420.001.jpg
case_images: fig1
case_images: MEPs across 10 trials, each with a peak-to-peak amplitude (Figure 1) of at least 200 muV. MEPs were then elicited from the motor cortex at stimulus intensities of 105%, 115%, 120%, 125%, 130%, 135%, and 145%
case_images: Stimulus response curves at the baseline testing session produced by calculating average MEP magnitudes at TMS stimulus intensities equal to 115%, 120%, 125%, 130%, 135%, and 145% of the active motor threshold (AMT) for each limb. Values are represented as a normalized percentage of the average MEP amplitude calculated at 105% of the AMT for the affected limb (squares and solid lines) and unaffected limb (diamonds and dashed lines). Thick lines correspond to the first baseline testing session (before the initial 30-minute exercise session), while thin lines correspond to the second baseline testing session (immediately following the initial 30-minute exercise session).
case_images: CRIM.RHEUMATOLOGY2011-537420.002.jpg
case_images: PMC3420629_01_CRIM.RHEUMATOLOGY2011-537420.002.jpg
case_images: fig2
case_images: Between-limb differences in MEP amplitude were evident across all stimulus intensities at baseline (Figure 2).
case_images: Stimulus response curves for the affected limb from the baseline, preexercise testing session (thick line) and 8-week follow-up testing session (thin line) produced by calculating average MEP amplitudes at TMS stimulus intensities equal to 115%, 120%, 125%, 130%, 135%, and 145% of the active motor threshold (AMT). Values are represented as a normalized percentage of the average MEP magnitude calculated at 105% of the AMT from each testing session.
case_images: CRIM.RHEUMATOLOGY2011-537420.003.jpg
case_images: PMC3420629_01_CRIM.RHEUMATOLOGY2011-537420.003.jpg
case_images: fig3
case_images: Following 8 weeks of lower limb muscle strengthening, MEP amplitudes in the affected limb increased, compared to baseline at all stimulus intensities except 115% of AMT (Figure 3).