case_images: PMC10415045_01
case_images: (A) Magnetic resonance angiography showing stenosis and thickening of the wall of the abdominal aortic. (B) Abdominal CT showing liver cirrhosis, splenomegaly, portal hypertension, and ascites. (C) Magnetic resonance imaging showing joint effusion, synovial thickening, and bone destruction of the distal femur and proximal tibia in the left knee. (D) Liver biopsy showing epithelioid granulomas with multinucleated giant cell reaction [hematoxylin and eosin (H&E)-stained section, 150x magnification].
case_images: fped-11-1063222-g002.jpg
case_images: PMC10415045_01_fped-11-1063222-g002.jpg
case_images: F2
case_images: Magnetic resonance (MR) angiography showed stenosis and thickening of the wall of the abdominal aortic at the level of the renal artery (Figure 2A) and mild hepatosplenomegaly. Abdominal computed tomography (CT) showed liver cirrhosis, splenomegaly, portal hypertension, and ascites (Figure 2B). MR imaging showed joint effusion with extensive synovial thickening and bone destruction of the distal femur and proximal tibia in the left knee (Figure 2C). A liver biopsy revealed cirrhosis and hepatic granulomas (Figure 2D).
case_images: (A,B) Camptodactyly of the fingers and toes. (C,D) Ichthyosiform rashes on the trunk and limbs.
case_images: fped-11-1063222-g003.jpg
case_images: PMC10415045_01_fped-11-1063222-g003.jpg
case_images: F3
case_images: On physical examination, he appeared with camptodactyly (Figures 3A,B) and boggy swelling of both wrists and knees. Ichthyosiform rashes on the whole body (Figures 3C,D) and splenomegaly were noted.