case_images: PMC8383176_01
case_images: Enhanced computed tomography of the scrotum showed a nodular hyperdense shadow in the right epididymis (arrow).
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case_images: PMC8383176_01_fimmu-12-717902-g001.jpg
case_images: f1
case_images: Enhanced computed tomography of the scrotum showed a nodular hyperdense shadow with a diameter of approximately 23 mm on the right epididymis, with significant heterogeneous enhancement on the enhanced scan (Figure 1).
case_images: Pathological biopsy of the right epididymis showed infiltration of plasma cells, lymphocytes, and a few neutrophils with occlusive vasculitis changes in the tissue (HE, x40) (A). Immunostains showed a markedly increased number of IgG4+ plasma cells as well as an increased IgG4+/IgG+ ratio (IgG4 immunostain, x40) (B).
case_images: fimmu-12-717902-g002.jpg
case_images: PMC8383176_01_fimmu-12-717902-g002.jpg
case_images: f2
case_images: Pathological biopsy of the right epididymis showed infiltration of plasma cells, lymphocytes, and a few neutrophils with occlusive vasculitis changes in the tissue (Figure 2A). IgG4+ plasma cells stained positive, with an IgG4/IgG ratio of more than 40% and more than 30 IgG4+ plasma cells per high-power field (Figure 2B).
case_images: Timeline of diagnosis, treatment, and prognosis in this case.
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case_images: PMC8383176_01_fimmu-12-717902-g003.jpg
case_images: f3
case_images: The timeline of diagnosis, treatment, and prognosis for this case is shown in Figure 3.