case_images: PMC11823877_01
case_images: (A) Sagittal short tau inversion recovery magnetic resonance imaging (MRI) image shows hyperintense signal involving the T11, T12, and S1 vertebral bodies (arrow) with no involvement of the adjacent intervertebral discs. (B) D12 vertebral body on axial image of MRI (Dense infiltration of acute and chronic inflammatory cells).
case_images: JOCR-15-106-g001.jpg
case_images: PMC11823877_01_JOCR-15-106-g001.jpg
case_images: F1
case_images: An MRI of the lumbar spine revealed destruction of the D12 and S1 vertebral bodies with paravertebral collection (Fig. 1).
case_images: Axial computed tomography images through the lung apex shows multiple bronchocentric nodules with adjacent endobronchial nodules in the right lung (arrow).
case_images: JOCR-15-106-g002.jpg
case_images: PMC11823877_01_JOCR-15-106-g002.jpg
case_images: F2
case_images: A repeat CT scan revealed nodular lesions in the lungs, spleen, and liver (Fig. 2).
case_images: Coronal reconstructed 18F-fluorodeoxyglucose positron emission tomography-computed tomography scan shows increased metabolic activity in multiple pulmonary nodules; also seen is focal metabolic activity in the right lobe of the liver and spleen (arrows) with moderate hepatosplenomegaly.
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case_images: F3
case_images: PET-CT scans showed multiple metabolically active lymph nodes and lesions in the liver, spleen, and lungs (Fig. 3).
case_images: (A) Hematoxylin and eosin stain (x20) showing a polymorphous population of cells with mononuclear/binuclear Reed Sternberg cells (arrow, Inset x40). (B) Immunohistochemistry for CD30 shows membrane and Golgi positivity (arrow) in Reed Sternberg cells (x20).
case_images: JOCR-15-106-g004.jpg
case_images: PMC11823877_01_JOCR-15-106-g004.jpg
case_images: F4
case_images: The final diagnosis was HL with a high load of Reed-Sternberg cells (Fig. 4).