case_images: PMC9157756_01
case_images: Brain magnetic resonance imaging done on the first hospital day. T1WI/T2WI/Post-Contrast T1WI didn't show any abnormality.
case_images: fmed-09-855020-g0001.jpg
case_images: PMC9157756_01_fmed-09-855020-g0001.jpg
case_images: F1
case_images: Brain MRI (Figure 1), lung CT, and Doppler echocardiography showed no abnormalities.
case_images: Repeated mNGS of blood results of the patient. The coverage and proportion of Coxiella burnetii detected by mNGS in blood (A) and reexamined mNGS in blood (B). mNGS, metagenomics next-generation sequencing.
case_images: fmed-09-855020-g0002.jpg
case_images: PMC9157756_01_fmed-09-855020-g0002.jpg
case_images: F2
case_images: Blood mNGS detected 20 reads of C. burnetii on day 3 (Figure 2A) but CSF mNGS turned to a negative result. Therefore, the diagnosis of acute Q fever had been proven by a positive of the second mNGS analysis of blood [10 unique reads of C. burnetii (Figure 2B)] and a good response to doxycycline.
case_images: Longitudinal analysis of temperature and medication. After using specific drugs:doxycycline, the temperature was under control and didn't bounce back again.
case_images: fmed-09-855020-g0003.jpg
case_images: PMC9157756_01_fmed-09-855020-g0003.jpg
case_images: F3
case_images: Empiric acyclovir and moxifloxacin had been stopped due to the definitive diagnosis (Figure 3).