case_images: PMC3907403_01
case_images: Bone marrow biopsy intertrabecular space showing bizarre multinucleated cells with hyperchromatic nuclei embedded in bed of necrosis and haemorrhage (200x) H&E.
case_images: can-8-393fig1.jpg
case_images: PMC3907403_01_can-8-393fig1.jpg
case_images: figure1
case_images: However, a bone marrow examination was conducted prior to this and revealed erythroid hyperplasia, while a bone marrow biopsy showed extensive necrosis, bizarre cells, multinucleated cells, abnormal mitosis, and haemorrhage with normal haematopoietic areas interspersed in between (Figures 1 and 2).
case_images: Tumour tissue showing predominantly polygonal cells with moderate to abundant clear cytoplasm, nucleus with high N/C ratio and coarse chromatin and prominent nucleoli (400x) H&E.
case_images: can-8-393fig2.jpg
case_images: PMC3907403_01_can-8-393fig2.jpg
case_images: figure2
case_images: However, a bone marrow examination was conducted prior to this and revealed erythroid hyperplasia, while a bone marrow biopsy showed extensive necrosis, bizarre cells, multinucleated cells, abnormal mitosis, and haemorrhage with normal haematopoietic areas interspersed in between (Figures 1 and 2).
case_images: Tumour cells showing positive staining for betaHCG on IHC (400x).
case_images: can-8-393fig3.jpg
case_images: PMC3907403_01_can-8-393fig3.jpg
case_images: figure3
case_images: On Immunohistochemistry (IHC) tumour cells were positive for betaHCG (Figure 3) while negative for CD31 and CK.