case_images: PMC3385281_01
case_images: Clinical photograph (after biopsy) of case 1 showing residual ulcerated light red plaque on medial aspect of left leg
case_images: IJMPO-33-54-g001.jpg
case_images: PMC3385281_01_IJMPO-33-54-g001.jpg
case_images: F1
case_images: Recently, the lesion was rapidly increasing in size and subsequently ulcerated [Figure 1].
case_images: Photomicrograph (low power) showing diffuse nonepidermotropic infiltrates of tumor cells in the papillary and reticular dermis (Hematoxylin and Eosin, x100)
case_images: IJMPO-33-54-g002.jpg
case_images: PMC3385281_01_IJMPO-33-54-g002.jpg
case_images: F2
case_images: The tumor cells were located in the papillary and reticular dermis and reaching the interface between dermis and subcutis [Figure 2].
case_images: Photomicrograph showing CD20 positivity (cytoplasmic membrane) by tumor cells (x400)
case_images: IJMPO-33-54-g003.jpg
case_images: PMC3385281_01_IJMPO-33-54-g003.jpg
case_images: F3
case_images: Immunohistochemistry (IHC) revealed expression of CD20, CD19, Bcl-2, Bcl- 6 and MUM-1 by tumor cells, while they were negative for CD10, CD30, EMA, CD3, and CD5 [Figures 3 and 4].
case_images: Photomicrograph showing Bcl-6 positivity (nuclear) by tumor cells (x100)
case_images: IJMPO-33-54-g004.jpg
case_images: PMC3385281_01_IJMPO-33-54-g004.jpg
case_images: F4
case_images: Immunohistochemistry (IHC) revealed expression of CD20, CD19, Bcl-2, Bcl- 6 and MUM-1 by tumor cells, while they were negative for CD10, CD30, EMA, CD3, and CD5 [Figures 3 and 4].
case_images: PMC3385281_02
case_images: Photomicrograph (high power) showing monomorphic large cells arranged in diffuse sheets. The cells have the high nuclearcytoplasmic ratio and prominent single to multiple nucleoli (Hematoxylin and Eosin, x400)
case_images: IJMPO-33-54-g005.jpg
case_images: PMC3385281_02_IJMPO-33-54-g005.jpg
case_images: F5
case_images: Incisonal biopsy was taken and histopathological examination revealed similar findings as in case 1 [Figure 5].