case_images: PMC9977208_01
case_images: Pink atrophic plaque with linear hyperkeratotic borders, central fissuring, and erosions extending from the right thenar eminence to the first webspace
case_images: cureus-0015-00000034401-i01.jpg
case_images: PMC9977208_01_cureus-0015-00000034401-i01.jpg
case_images: FIG1
case_images: He denied any pruritus or tenderness in the affected region aside from the areas of denuded skin (Figure 1). Physical examination revealed a pink atrophic plaque with linear hyperkeratotic borders along the right thenar eminence extending to the first webspace (Figure 1).
case_images: Punch biopsy demonstrating sharply demarcated hypokeratosis of stratum corneum adjacent to normal-appearing acral skin, a characteristic finding in CPH (Hematoxylin and eosin stain; original magnification X50). CPH: Circumscribed palmar hypokeratosis.
case_images: cureus-0015-00000034401-i02.jpg
case_images: PMC9977208_01_cureus-0015-00000034401-i02.jpg
case_images: FIG2
case_images: The biopsy revealed a sharply demarcated hypokeratosis of the epidermis with some parakeratosis and basal keratinocyte atypia (Figures 2, 3).
case_images: Higher power magnification demonstrating parakeratosis, basal keratinocyte atypia, and lichenoid inflammation (Hematoxylin and eosin stain; original magnification X100)
case_images: cureus-0015-00000034401-i03.jpg
case_images: PMC9977208_01_cureus-0015-00000034401-i03.jpg
case_images: FIG3
case_images: The biopsy revealed a sharply demarcated hypokeratosis of the epidermis with some parakeratosis and basal keratinocyte atypia (Figures 2, 3).
case_images: Small heme-crusted papule in the right first webspace with some faint erythema and scale and otherwise normal skin; this figure shows the improvement at two-month follow-up.
case_images: cureus-0015-00000034401-i04.jpg
case_images: PMC9977208_01_cureus-0015-00000034401-i04.jpg
case_images: FIG4
case_images: Physical examination revealed a small heme-crusted papule at the right first webspace with some faint scale and erythema and otherwise normal skin (Figure 4).