case_images: PMC8684531_01
case_images: Fundus photograph of the right eye (a) revealed normal fundus appearance. Montage fundus photograph of the left eye (b) revealed vitreous hemorrhage, moderately pale optic disc, macular hemorrhage, extensive peripheral retinal avascular area, sea fan neovascularization, and small fibrotic tissue in the temporal midperipheral retina.
case_images: CRIOPM2021-5988889.001.jpg
case_images: PMC8684531_01_CRIOPM2021-5988889.001.jpg
case_images: fig1
case_images: Funduscopic examination of the left eye revealed vitreous hemorrhage, moderately pale optic disc, macular hemorrhage, extensive peripheral retinal avascular area, sea fan neovascularization, and small fibrotic tissue in the temporal midperipheral retina (Figure 1).
case_images: Horizontal macular optical coherence tomography (OCT) of the right eye (a) revealed the normal macular structure and in the left eye (b) revealed inner retinal irregularity and thinning along with foveal splaying (saucerization of the foveal pit).
case_images: CRIOPM2021-5988889.002.jpg
case_images: PMC8684531_01_CRIOPM2021-5988889.002.jpg
case_images: fig2
case_images: Hemoglobin electrophoresis showed the presence of 57.6% hemoglobin A (HbA), 37.6% hemoglobin S, 2.4% hemoglobin A2, and 2.4% hemoglobin F, which was compatible with the diagnosis of sickle cell trait.
case_images: CRIOPM2021-5988889.003.jpg
case_images: PMC8684531_01_CRIOPM2021-5988889.003.jpg
case_images: fig3
case_images: Hemoglobin electrophoresis showed the presence of 57.6% hemoglobin A (HbA), 37.6% HbS, 2.4% HbA2, and 2.4% HbF, which was compatible with the diagnosis of sickle cell trait (Figure 3).
case_images: Montage fundus photograph of the left eye 6 months later revealed that vitreous and preretinal hemorrhages cleared, sea fan neovascularization partially regressed, and fibrotic membrane extended in the temporal midperipheral area.
case_images: CRIOPM2021-5988889.004.jpg
case_images: PMC8684531_01_CRIOPM2021-5988889.004.jpg
case_images: fig4
case_images: On examination, vitreous hemorrhage was cleared and sea fan neovascularization regressed clinically (Figure 4).
case_images: Montage midphase fluorescein angiography of the right eye (a) showed unremarkable findings but in the left eye (b) revealed residual peripheral avascular area, laser scars, and partially regressed neovascularizations corresponding to the leakage areas.
case_images: CRIOPM2021-5988889.005.jpg
case_images: PMC8684531_01_CRIOPM2021-5988889.005.jpg
case_images: fig5
case_images: Fluorescein angiography (Heidelberg Engineering GmbH, Heidelberg, Germany) showed normal foveal avascular zone size, residual peripheral avascular area, laser scars, and partially regressed neovascularization at the midperipheral retina (Figure 5).