case_images: PMC6874140_01
case_images: Percent change in targeted blood proteins during RAAM. A previous study determined that these proteins are not acutely upregulated following an exercise bout, potentially implicating them as strong candidates for NFOR monitoring in individuals.
case_images: fphys-10-01410-g001.jpg
case_images: PMC6874140_01_fphys-10-01410-g001.jpg
case_images: F1
case_images: Blood sample analysis indicated the largest serum protein increases during RAAM were immune-related proteins involved in complement activation and the acute phase response (Figure 1).
case_images: Intensity values for serum amyloid A4 (SAA4) before, during (morning and evening), and after RAAM competition.
case_images: fphys-10-01410-g002.jpg
case_images: PMC6874140_01_fphys-10-01410-g002.jpg
case_images: F2
case_images: A 359% increase in complement component C7 (CO7), a 231% increase in complement C4-B (CO4B), a 210% increase in serum amyloid A-4 protein (SAA4) (see Figure 2 for the time course of changes in SAA4), a 191% increase in Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4), and a 188% increase in alpha-1-antitrypsin (A1AT), occurred due to RAAM.