case_images: PMC11180431_01
case_images: (a) Prior to treatment. (b) The plaques were lighter in color after one year of treatment.
case_images: VHRM-20-251-g0001.jpg
case_images: PMC11180431_01_VHRM-20-251-g0001.jpg
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case_images: Physical examination revealed firm, red plaques, and elevated cutaneous temperature with no pain (Figure 1a). One year later, there was a noticeable lightening of lesion color, resolution of the induration, and a decrease in cutaneous temperature (Figure 1b).
case_images: (a) B-ultrasound examination showed hyperechoic area with vascular echo. (b) Follow-up B-ultrasound showed scattered hyperechoic areas with a little blood flow signals.
case_images: VHRM-20-251-g0002.jpg
case_images: PMC11180431_01_VHRM-20-251-g0002.jpg
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case_images: The diameter of the thicker blood vessels was approximately 0.16cm (Figure 2a). Follow-up B-ultrasound revealed a reduction in thickness to approximately 0.21 cm with minimal blood flow signals (Figure 2b).
case_images: (a) Histopathological showing focal, well-circumscribed nodules comprised of atypical spindle cells (HE, x50). (b) The spindle-shaped endothelial cells aligned to form a slit-like vascular channels (arrow, HE, x100). (c) The proliferated vessels were positive for CD31(CD31, x50). (d) The proliferated vessels were positive for CD34(CD34, x50). (e) The proliferated vessels were negative for GLUT-1 (GLUT-1, x50). (f) D2-40 staining was negative in the center of the lesion and positive in the surrounding dilated lymphatic vessels (D2-40, x50).
case_images: VHRM-20-251-g0003.jpg
case_images: PMC11180431_01_VHRM-20-251-g0003.jpg
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case_images: Histological examination of a biopsy sample from the plaques identified blood vessels in a tufted or plexiform distribution, CD31(+), CD34(+), D2-40(-), and GLUT-1(-) (Figure 3).