case_images: PMC10898855_01
case_images: Some representative images about malignant melanoma in this case. a-c The tumor appears as a green bulge by hysteroscopy. d Laparoscopically, we saw a black lymph node beside the left external iliac artery. e Postoperative section view of the specimen. A melanocyte cluster-like mass was found at the bottom of the uterus and the other lesion was located in the cervical canal.
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case_images: PMC10898855_01_cro-2024-0017-0001-535635_F01.jpg
case_images: F1
case_images: After admission, she underwent a hysteroscopy, which revealed a greenish protruding mass measuring 3 x 2 cm on the anterior wall of the uterus (Fig. 1a-c). Shockingly, a black lymph node about 1.2 x 1.0 cm in size was observed beside the left external iliac artery during the operation, and an enlarged lymph node was found beside the left groin (Fig. 1d), which indicates possible nodal metastases. The resected specimen was then dissected, a 5 x 3.5 x 2 cm melanocyte cluster-like mass was found at the bottom of the uterus, and the other lesion was located in the cervical canal, with a size of 1.3 x 1 cm (Fig. 1e). Fig. 1; for all online suppl. material, see https://doi.org/10.1159/000535635).
case_images: Representative images about HE staining of some specimens. a HE staining representative image of endometrial tissue. It shows the existence of tumor cells with a wide cytoplasm containing melanin pigment. The tumor cells are nested and separated by fibrous vessels. b HE staining representative image of metastatic melanoma of gastric fundus. It shows about 15 heteromorphic cells were nested and contained melanin in the cytoplasm.
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case_images: PMC10898855_01_cro-2024-0017-0001-535635_F02.jpg
case_images: F2
case_images: The final pathological diagnosis was PMME (Fig. 2a). The pathological results of biopsy confirmed metastatic MM (Fig. 2b).