case_images: PMC10189115_01
case_images: (A) Left fallopian tube invasive serous carcinoma (high-grade), bilateral ovaries, uterus, cervix, omentum, right fallopian tube, appendix, and dome margin with no tumor tissue (H&E staining, 200x). (B) Immunostaining for CA125 showing a positive reaction (200x). (C) Immunostaining for CR showing a positive reaction (200x). (D) Immunostaining for P53 showing a positive reaction (200x). (E) Immunostaining for WT1 showing a positive reaction (200x). (F) Immunostaining for CKL showing a positive reaction (200x). (G) Immunostaining for P16 showing a positive reaction (200x). (H) Immunostaining for CD10 showing a negative reaction (200x).
case_images: fonc-13-1079044-g001.jpg
case_images: PMC10189115_01_fonc-13-1079044-g001.jpg
case_images: f1
case_images: Histological examination of the resected specimen revealed a high-differentiated serous carcinoma of the left fallopian tube with serosa invasion ( Figures 1A-H ).
case_images: Abdominal computed tomography showing a low-density lesion in the low pole of the spleen with contrast enhancement during the arterial phase. (A) Arterial phase. (B) Venous phase.
case_images: fonc-13-1079044-g002.jpg
case_images: PMC10189115_01_fonc-13-1079044-g002.jpg
case_images: f2
case_images: The abdominal CT scan revealed a 4.0x3.0 cm low-density lesion in the spleen that was potentially malignant, with mild contrast enhancement during the arterial and no lymphadenectasis or distant metastasis ( Figures 2A, B ).
case_images: (A) Postoperative pathological result of the splenic lesion: serous carcinoma from the primary fallopian tube carcinoma (H&E staining, 200x). (B) Immunostaining for CA125 showing a positive reaction (200x). (C) Immunostaining for CK7 showing a positive reaction (200x). (D) Immunostaining for ER showing a positive reaction (200x). (E) Immunostaining for NapsinA showing a negative reaction (200x). (F) Immunostaining for Inhibin-alpha showing a negative reaction (200x). (G) Immunostaining for Vimentin showing a negative reaction (200x).
case_images: fonc-13-1079044-g003.jpg
case_images: PMC10189115_01_fonc-13-1079044-g003.jpg
case_images: f3
case_images: The histopathological diagnosis confirmed the splenic metastasis from PFTC ( Figure 3A ), supported by immunohistochemical stains positive for CA125, CK-7, and ER and negative for NapsinA, Inhibin-alpha, and Vimentin ( Figure 3B-G ).