case_images: PMC10641789_01
case_images: The clinical tests and treatment timeline of the patient.
case_images: fcimb-13-1269963-g001.jpg
case_images: PMC10641789_01_fcimb-13-1269963-g001.jpg
case_images: f1
case_images: Initial treatment involved cefloxacin administration and fluid rehydration ( Figure 1 ), but his symptoms did not improve. Infectious diarrhea was highly suspected, and cefoperazone sulbactam (4g q8h) was given as empiric therapy ( Figure 1 ).
case_images: The proportion of detected Cryptosporidium parvum sequences in the total microbial sequences and the genome coverage (A) Day 3; blood samples (B) Day 6; anal swabs (C) Day 15; anal swabs.
case_images: fcimb-13-1269963-g002.jpg
case_images: PMC10641789_01_fcimb-13-1269963-g002.jpg
case_images: f2
case_images: After the sequence of human genome was excluded, mNGS identified 3,178 specific reads belong to C. parvum, accounting for 1.9% of nucleotide sequence coverage ( Figure 2A ). The results of child's tests showed that 92.2% (116,897) of pathogenic reads corresponded to C. parvum with a coverage of 61.9%, and neither parent was detected with any pathogen ( Figure 2B ). However, Candida tropicalis and Candida parapsilosis (302,484 and 5,320 specific reads) were also detected in this test ( Figure 2C ).