case_images: PMC10538527_01
case_images: (A) Timeline of an episode of care. The patient ingested 50 mg tid of eperisone hydrochloride for the first 3 days with no adverse effects. However, on the morning of the 4th day, the patient experienced frequent bilateral tonic seizures. The following day, the patient was admitted to the hospital and treated with diazepam, sodium valproate, and rehydration, after which the symptoms decreased and did not occur on the morning of the 2nd day after admission. The head MRI was normal on the 2nd day after admission, sodium valproate was discontinued on the 3rd day after admission, and the 24-h video EEG from the 3rd to the 4th day after admission was normal. (B) EEG showing low-to-medium amplitude alpha background EEG predominantly at 8.5-11.5 Hz in the quiet, awake with closed-eye state (a), and K complex waves during sleep (b).
case_images: fneur-14-1240526-g0001.jpg
case_images: PMC10538527_01_fneur-14-1240526-g0001.jpg
case_images: F1
case_images: The head magnetic resonance imaging (MRI) and 24-h video electroencephalogram (EEG) (Figure 1B) were normal. After eperisone hydrochloride discontinuation for more than five half-lives and his symptoms being effectively controlled, sodium valproate was discontinued on the 3rd day after admission, and the patient recovered and was discharged within 4 days without any adverse sequelae (Figure 1A).