case_images: PMC4784184_01
case_images: Initial clinical presentation:clinical composite photograph of the patient's left eye reveals an extensive fleshy salmon solid tumor of the conjunctiva extending into the orbit inferonasally
case_images: NAJMS-8-56-g001.jpg
case_images: PMC4784184_01_NAJMS-8-56-g001.jpg
case_images: F1
case_images: Upon further ophthalmic evaluation, a fleshy, salmon colored conjunctival tumor was identified in her left eye [Figure 1].
case_images: Histopathology from biopsied conjunctival lesion:photomicrograph reveals sheets of large neoplastic lymphoid cells with moderate nuclear pleomorphism, vesicular chromatin, and large nucleoli underlying normal epithelium. (H&E, 30X)
case_images: NAJMS-8-56-g002.jpg
case_images: PMC4784184_01_NAJMS-8-56-g002.jpg
case_images: F2
case_images: Histopathologic examination of the specimen revealed sheets of large neoplastic lymphoid cells with moderate nuclear pleomorphism, vesicular chromatin, and large nucleoli underlying the normal conjunctival epithelium [Figure 2].
case_images: Immunohistochemical stains of conjunctival lesion:photomicrographs of multiple immunohistochemical assays showed that the large lymphoid cells stained strongly positive for CD20 and MUM-1; it was also positive for Pax-5 and weakly positive for Bcl-6. The large lymphoid cells were negative for CD10. The small background lymphocytes stained positive with CD3
case_images: NAJMS-8-56-g003.jpg
case_images: PMC4784184_01_NAJMS-8-56-g003.jpg
case_images: F3
case_images: The small background lymphocytes were CD3-positive [Figure 3].