case_images: PMC11647275_01
case_images: Erythematous, edematous papules, and plaques on the trunk and proximal extremities.
case_images: gr1.jpg
case_images: PMC11647275_01_gr1.jpg
case_images: fig1
case_images: Physical examination revealed scattered, excoriated, erythematous, edematous papules, and plaques involving proximal extremities, thighs, and abdomen with periumbilical involvement (Fig 1).
case_images: A, Histopathological examination demonstrated mild spongiosis with a perivascular and interstitial inflammatory cell infiltrate comprising eosinophils and neutrophils with eosinophils preset at dermal-epidermal junction (DEJ). B, Direct immunofluorescence with linear deposition of immunoglobulin G (IgG) along DEJ.
case_images: gr2.jpg
case_images: PMC11647275_01_gr2.jpg
case_images: fig2
case_images: Given concern for a pregnancy-related dermatosis, skin biopsies for hematoxylin and eosin and direct immunofluorescence (DIF) were performed demonstrating an urticarial pattern of inflammation without vesiculation or subepidermal blister formation (Fig 2).