case_images: PMC1192792_01
case_images: Liver biopsy contains numerous neoplastic elongate cells consistent with malignant melanoma infiltration.
case_images: 1471-2407-5-67-1.jpg
case_images: PMC1192792_01_1471-2407-5-67-1.jpg
case_images: F1
case_images: Autopsy revealed >80% liver infiltration by melanoma (Figure 1), a diagnosis verified by an immunohistochemical phenotype of S-100 and HMB-45 positive cells (Figure 2).
case_images: Immunohistochemistry of the liver. S-100 antibody stains malignant melanocytes with a brown chromogen (diaminobenzidine). Rare negative cells (blue due to hematoxylin counterstaining) are intact hepatocytes.
case_images: 1471-2407-5-67-2.jpg
case_images: PMC1192792_01_1471-2407-5-67-2.jpg
case_images: F2
case_images: Autopsy revealed >80% liver infiltration by melanoma (Figure 1), a diagnosis verified by an immunohistochemical phenotype of S-100 and HMB-45 positive cells (Figure 2).