case_images: PMC10577444_01
case_images: (A) Neck ultrasonography showed a solid hypoechoic nodule measuring 16mmx11mmx13mm in the middle-lower part of the right thyroid. The nodule exhibited irregular shape and unclear border but without calcification and linear hyperechoic patterns. The ratio of nodule longitudinal diameter to transverse diameter was less than 1. (B) Color Doppler sonography revealed scanty blood flow within the nodule.
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case_images: PMC10577444_01_fonc-13-1234961-g001.jpg
case_images: f1
case_images: Color Doppler sonography indicated meager blood flow within the nodule ( Figure 1 ).
case_images: Immunohistochemically, the tumor cells were positively immunoreactive for CD5, CD117, P40, P53, Pax 8, and Bcl-2, and negatively for TTF-1.
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case_images: PMC10577444_01_fonc-13-1234961-g002.jpg
case_images: f2
case_images: Immunohistochemical analysis revealed that the tumor cells were positively reactive to CD5, CD117, CK19, P40, P53, Pax 8, and Bcl-2, and negative to thyroglobulin (Tg), thyroid transcription factor-1 (TTF-1), and calcitonin ( Figure 2 ).
case_images: Process of diagnosis and treatment for the case.
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case_images: PMC10577444_01_fonc-13-1234961-g003.jpg
case_images: f3
case_images: During the 4-year follow-up, which included physical examination of the neck, thyroid function tests, and US for the neck, she showed no signs of locally recurrent or distant disease ( Figure 3 ).