case_images: PMC10375206_01
case_images: (a) Macroscopic photography of the eyelid showing ulcerated mass on the eyelid. (b) Anterior segment photography showing ulcerated mass before punch biopsy.
case_images: BEJ-8-139-g001.jpg
case_images: PMC10375206_01_BEJ-8-139-g001.jpg
case_images: F1
case_images: A 28-year-old male was referred to our clinic for an ulcerated, hyperemic, and nodular mass on his right upper eyelid that grew rapidly within 2 weeks (Fig. 1a). Hence, the symptoms of the patient progressed despite treatment, a punch biopsy from the lesion was performed which did not distinguish infective pathologies or malignancy (Fig. 1b).
case_images: (a-c) Hematoxylin and eosin staining of dermis showing abundant eosinophils, histiocytes, and lymphoid infiltrate. (d) Immunohistochemical analysis revealing CD30-positive lymphocytes.
case_images: BEJ-8-139-g002.jpg
case_images: PMC10375206_01_BEJ-8-139-g002.jpg
case_images: F2
case_images: Abundant eosinophils, histiocytes, and lymphoid infiltrate were detected in dermis (Figures 2a-c). CD30-positive lymphocytes in immunohistochemical analysis (Fig. 2d). CD30-positive lymphoproliferative diseases and insect bite reactions were evaluated in the differential diagnosis.
case_images: (a) Photograph of the eyelid after incisional biopsy. (b) Tarsal conjunctival photography after the incisional biopsy.
case_images: BEJ-8-139-g003.jpg
case_images: PMC10375206_01_BEJ-8-139-g003.jpg
case_images: F3
case_images: However, following incisional biopsy, the lesion rapidly regressed in 7 days (Figs. 3a-b).