case_images: PMC11114444_01
case_images: CT of the lungs (A, B) diffuse ground-glass shadow and high-density shadow in both lungs were seen in the lung window and mediastinal window when the patient was first admitted to the hospital; (C, D) higher density was seen on repeat CT after a period of treatment; (E, F) higher density shadow was still seen on repeat CT before discharge, although the ground-glass shadow was absorbed.
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case_images: F1
case_images: C. Computed tomography (CT) scan revealed severe diffuse ground-glass opacities (Figure 1), calcification of heart valves (Figure 2), and gastric mucosa (Figure 2).
case_images: Extrapulmonary organ calcification (A) cardiac valve calcification; (B) Gastric mucosal calcification.
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case_images: F2
case_images: C. Computed tomography (CT) scan revealed severe diffuse ground-glass opacities (Figure 1), calcification of heart valves (Figure 2), and gastric mucosa (Figure 2).
case_images: (A) Painful skin followed by herpes and purpura; (B) follow-up skin condition. (C) Patient's buttocks after skin grafting.
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case_images: F3
case_images: A partial debridement of the patient's necrotic skin was performed, followed by a skin grafting procedure (Figure 3C).
case_images: Hematoxylin and eosin stain sections of lung tissue biopsy showing crystalline materials with calcification and foreign body (arrows) granulomas in the interstitium and alveolar cavity (x 100).
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case_images: F4
case_images: Lung tissue biopsy showed the presence of crystalline materials with calcification and granulomatous foreign bodies in the interstitium and alveolar cavity (Figure 4).
case_images: PMC11114444_02
case_images: (A) Painful skin followed by herpes and purpura; (B) follow-up skin condition. (C) Patient's buttocks after skin grafting.
case_images: fmed-11-1357260-g0003.jpg
case_images: PMC11114444_02_fmed-11-1357260-g0003.jpg
case_images: F3
case_images: A partial debridement of the patient's necrotic skin was performed, followed by a skin grafting procedure (Figure 3C).
case_images: (A) The patient's genetic test results suggested a mutation in the FBN1 gene. (B) Her son's test results also showed a mutation in the FBN1 gene. (C) Her daughter's results were normal.
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case_images: F5
case_images: H) (Figure 5), while her daughter's results were normal. Her 29-year-old son did not show clinical symptoms such as cough or dyspnea, and a CT scan of the lungs did not reveal any abnormalities.