case_images: PMC10589407_01
case_images: A, B) bone marrow aspirate smear examination: mature lympho-plasmacytoidic cells associated to variable size blast-like cells with thin chromatin and prominent nucleoli; may-Grunwald-Giemsa, x100 objective
case_images: PAMJ-45-158-g001.jpg
case_images: PMC10589407_01_PAMJ-45-158-g001.jpg
case_images: F1
case_images: The cells have an extended agranular cytoplasm with variable basophilia and the myeloperoxidase staining returned negative (Figure 1).
case_images: flow cytometry representation of the CD45-dim population; (gating S) presence of an immature population, (gating AB) moderately expressed CD19 with a highly expressed CD38
case_images: PAMJ-45-158-g002.jpg
case_images: PMC10589407_01_PAMJ-45-158-g002.jpg
case_images: F2
case_images: The fluorescence intensity was different when compared with the lymphocytes  profile (CD38 low and CD19 high) (Figure 2 and Figure 3).
case_images: flow cytometry representation of CD2, CD3 positive lymphocytes; (AB) presence of an immature population with a highly expressed CD38 (CD2 negative, CD3 positive), (AE) normal mature lymphocyte (CD38 low CD2 positive, CD3 positive)
case_images: PAMJ-45-158-g003.jpg
case_images: PMC10589407_01_PAMJ-45-158-g003.jpg
case_images: F3
case_images: The fluorescence intensity was different when compared with the lymphocytes  profile (CD38 low and CD19 high) (Figure 2 and Figure 3).
case_images: bone marrow location of a plasmablastic lymphoma; medullary spaces are infiltrated with a dense lymphomatous proliferation (hematoxylin eosin x100); tumor cells are medium to large sized and show diffuse plasmacytic differentiation with abundant cytoplasm and eccentric nuclei (hematoxylin eosin x400)
case_images: PAMJ-45-158-g004.jpg
case_images: PMC10589407_01_PAMJ-45-158-g004.jpg
case_images: F4
case_images: A fibrous background was observed with reactional lymphocytes (Figure 4).
case_images: immunohistochemistry of the plasmablastic cells (x200); (A) cells are strongly positive for CD138; (B) cells are focally positive for EMA; (C) cells are negative for CD20
case_images: PAMJ-45-158-g005.jpg
case_images: PMC10589407_01_PAMJ-45-158-g005.jpg
case_images: F5
case_images: Immunohistochemistry showed a diffuse positivity of the tumor cells for CD138, focal expression of EMA (Figure 5), and was negative for CD45, CD79a, CD3, CD30, CD5, CD10, MuM1, Bcl6, and Cyclin D1.