case_images: PMC6381904_01
case_images: PMC6381904_02
case_images: Adenocarcinoma which is tubular, moderately differentiated, infiltrating into the deep muscle layer. a H&E, magnification x40. b H&E, magnification x100.
case_images: crg-0013-0017-g01.jpg
case_images: PMC6381904_02_crg-0013-0017-g01.jpg
case_images: F1
case_images: Microscopic examination of the masses showed sigmoid colon tubular adenocarcinoma grade II infiltrating into the deep muscle layer (Fig. 1).
case_images: PMC6381904_03
case_images: Endoscopic image: anastomosis was found 20 cm away from the anus edge, and the mucosa of the anastomosis was smooth, with no erosion, ulcer or tumor (a). Three polypoid growths were seen 45 cm away from the anal margin (b-d), with a size of about 0.2 cm x 0.2 cm to 0.4 cm x 0.4 cm, and one polyp surface was flushed (b).
case_images: crg-0013-0017-g02.jpg
case_images: PMC6381904_03_crg-0013-0017-g02.jpg
case_images: F2
case_images: At reexamination of the electron colonoscopy on August 1, 2017, multiple polypoid eminences of sigmoid colon were found with a high possibility of inflammatory hyperplasia (Fig. 2).
case_images: A large number of lymphoid tissue hyperplasia under the mucosa of sigmoid colon, with a single morphology. a H&E, magnification x40. b H&E, magnification x100. c CD5, magnification x100. d cyclin D1, magnification x100. e CD20, magnification x100. f Ki-67, magnification x100. g CD10, magnification x100. h CD23, magnification x100.
case_images: crg-0013-0017-g03.jpg
case_images: PMC6381904_03_crg-0013-0017-g03.jpg
case_images: F3
case_images: Microscopic examination of the polyps showed a large number of hyperplastic lymphoid cells under the mucosa with a single shape (Fig. 3a, b). On examination of immunohistochemistry (IHC), hyperplastic lymphocytes were positive for CD5 (Fig. 3c), cyclin D1 (Fig. 3d), CD20 (Fig. 3e), CD79alpha, Bcl-2, CD43, and Ki-67 (40%) (Fig. 3f), and negative for CD10 (Fig. 3g) and CD23 (Fig. 3h).