case_images: PMC8573166_01
case_images: Gene check analysis showed that the patient had an EGFR exon20 insertion (p.D770-N771insGT) mutation.
case_images: fonc-11-733276-g001.jpg
case_images: PMC8573166_01_fonc-11-733276-g001.jpg
case_images: f1
case_images: Next-generation sequencing (NGS) testing showed an EGFR exon20 insertion (p.D770-N771insGT) mutation with concurring ERBB2 and TP53 mutations ( Figure 1 ).
case_images: Patient dynamic changes in the chest CT and brain MRI during treatments.
case_images: fonc-11-733276-g002.jpg
case_images: PMC8573166_01_fonc-11-733276-g002.jpg
case_images: f2
case_images: The dynamic changes in chest CT and brain MRI during treatments are shown in  Figure 2 .
case_images: Patient clinical course including treatment process and relevant assessment.
case_images: fonc-11-733276-g003.jpg
case_images: PMC8573166_01_fonc-11-733276-g003.jpg
case_images: f3
case_images: On March 20th, the patient died with an overall survival time of 13.5 months.  Figure 3  shows a flow pathway for treatment and assessment.