case_images: PMC11670901_01
case_images: A chest x-ray taken on the day of the measurements, at 10 cm H2O of PEEP. PEEP, positive end-expiratory pressure.
case_images: mat-71-e12-g001.jpg
case_images: PMC11670901_01_mat-71-e12-g001.jpg
case_images: F1
case_images: An x-ray of the chest showed extensive atelectasis of the dependent lung regions combined with cardiogenic pulmonary edema (Figure 1), initially managed with a PEEP of 10 cm H2O, associated with a Plateau Pressure of 25 cm H2O and a driving pressure of 15 cm H2O.
case_images: Changes in RV PV loops and respiratory system mechanics at different PEEP levels in a patient supported by 3.5 L/minute of VA-ECMO blood flow. CRS, respiratory system compliance; Dp, driving pressure; Ea, arterial elastance; EDV, end-diastolic volume; Ees, ventricular end-systolic elastance; Ees/Ea, ventriculo-arterial coupling; PE, potential energy; PEEP, positive end-expiratory pressure; SV, stroke volume; SW, stroke work; SW/PVA, stroke work/pressure-volume area ratio. VA-ECMO, veno-arterial extracorporeal membrane oxygenation.
case_images: mat-71-e12-g002.jpg
case_images: PMC11670901_01_mat-71-e12-g002.jpg
case_images: F2
case_images: ECMO blood flow was 3.5 L/minute (1.7 L/minute/Body Surface Area (BSA)) and the ventilator was set in a volume controlled mode with tidal volumes of 450 ml (6 ml/kg of ideal body weight), respiratory rate of 12 breaths/minute and FiO2 at both natural and membrane lung of 0.65 (Figure 2). Each PEEP level was kept for 5 minutes, vasoactive agents were kept constant (noradrenaline 0.05 mcg/kg/minute, milrinone 0.25 mcg/kg/minute, dobutamine 3 mcg/kg/minute), and no fluid load was administered.