case_images: PMC5565258_01
case_images: Subungual hyperkeratosis (arrow) (A, B), onycholysis, onychomadesis, and a transparent serous exudate emanating from the toenail bed (circle) (A).
case_images: dddt-11-2373Fig1.jpg
case_images: PMC5565258_01_dddt-11-2373Fig1.jpg
case_images: f1-dddt-11-2373
case_images: Examination of the patient revealed toenail changes including subungual hyperkeratosis, onycholysis, onychomadesis, and a transparent serous exudate emanating from all the nail beds (Figure 1).
case_images: The patient's hands became desquamated and red (B). Fingernail changes included dark pigmentations, Beau's lines, and subungual hyperkeratosis (A).
case_images: dddt-11-2373Fig2.jpg
case_images: PMC5565258_01_dddt-11-2373Fig2.jpg
case_images: f2-dddt-11-2373
case_images: Her hands had desquamation and redness, and fingernail changes included dark pigmentations, Beau's lines, and subungual hyperkeratosis (Figure 2).
case_images: Dysesthesia symptoms remained, and all the toenails exhibited defects (arrow) (A) or deformities (circle) (A, B) at a 24-month follow-up.
case_images: dddt-11-2373Fig3.jpg
case_images: PMC5565258_01_dddt-11-2373Fig3.jpg
case_images: f3-dddt-11-2373
case_images: The dysesthesia symptoms remained, and all the toenails exhibited defects or deformities (Figure 3); however, her hands returned to normal and her fingernails improved at a 24-month follow-up (Figure 4).
case_images: The patient's hands returned to normal (B). Fingernail changes improved at a 24-month follow-up (A).
case_images: dddt-11-2373Fig4.jpg
case_images: PMC5565258_01_dddt-11-2373Fig4.jpg
case_images: f4-dddt-11-2373
case_images: The dysesthesia symptoms remained, and all the toenails exhibited defects or deformities (Figure 3); however, her hands returned to normal and her fingernails improved at a 24-month follow-up (Figure 4).