case_images: PMC6710319_01
case_images: Chest CT before and after video-assisted wedge resection of left upper lung lobe. (A) The lung tumor located in the left upper lung lobe; (B) Fourteen months after resection of lung tumor in the left upper lung lobe.
case_images: fonc-09-00784-g0001.jpg
case_images: PMC6710319_01_fonc-09-00784-g0001.jpg
case_images: F1
case_images: Fourteen months prior to this admission, he had undergone video-assisted thoracic surgery for the wedge resection of left upper lung lobe due to the left upper lung mass found in chest CT scan (Figure 1A), and pathology revealed infiltrating lung adenocarcinoma with T2N0M0 staging (Figure 2A). Re-examination of chest CT on this admission indicated no evidence of disease recurrence after lung lesion resection (Figure 1B).
case_images: Histopathology of lung and urethra cancer. (A) Primary adenocarcinoma of lung (Hematoxylin and Eosin, original magnification x 100). (B) Metastatic urethral adenocarcinoma (Hematoxylin and Eosin, original magnification x 100). Black arrows indicated adenocarcinoma.
case_images: fonc-09-00784-g0002.jpg
case_images: PMC6710319_01_fonc-09-00784-g0002.jpg
case_images: F2
case_images: Fourteen months prior to this admission, he had undergone video-assisted thoracic surgery for the wedge resection of left upper lung lobe due to the left upper lung mass found in chest CT scan (Figure 1A), and pathology revealed infiltrating lung adenocarcinoma with T2N0M0 staging (Figure 2A). Routine hematoxylin and eosin stained sections indicated adenocarcinoma (Figure 2B) and further immunohistochemical staining showed negative PSA, positive thyroid transcription factor 1 (TTF1) and Napsin A, confirming the urethral metastasis of lung adenocarcinoma.
case_images: Tumor located in the membranous urethra under transurethral endoscopy. The black arrow indicated urethral tumor, while white arrow indicated normal posterior urethra.
case_images: fonc-09-00784-g0003.jpg
case_images: PMC6710319_01_fonc-09-00784-g0003.jpg
case_images: F3
case_images: Urethrocystoscopy under general anesthesia found the mass in the membranous urethra near the verumontanum (Figure 3), and transurethral loop electrosurgical excision was conducted to remove the mass.