case_images: PMC7441430_01
case_images: Zosteriform vesicle-like papules, measuring 0.5-1.0 cm on the left breast. Pink or red, firm, and tender.
case_images: CRIDM2020-8880604.001.jpg
case_images: PMC7441430_01_CRIDM2020-8880604.001.jpg
case_images: fig1
case_images: The lesions were pink or red, firm, and tender (Figure 1).
case_images: Skin biopsy revealed (a) blue nodular lesions infiltrating in the dermis, composed of clustered heterogeneous tumor cells with glandular formation (H&E, magnification: x20); (b) some tumor cells were detected within vessels or lymphatic vessels (H&E, magnification: x40); (c) some cells were blue and transparent, and mitosis was significant (H&E, magnification: x200).
case_images: CRIDM2020-8880604.002.jpg
case_images: PMC7441430_01_CRIDM2020-8880604.002.jpg
case_images: fig2
case_images: Mitosis was significant (Figures 2(a)-2(c)).
case_images: Immunohistochemical stain highlighting the tumor cells, showing (a) CK-7, (b) EMA, and (c) TTF-1 positive.
case_images: CRIDM2020-8880604.003.jpg
case_images: PMC7441430_01_CRIDM2020-8880604.003.jpg
case_images: fig3
case_images: In immunohistochemistry, tumor cells were positive for cytokeratin (CK), cytokeratin-7 (CK7), thyroid transcription factor-1 (TTF1), and EMA and negative for cytokeratin-20 (CK20), carcinoembryonic antigen (CEA), and gross cystic disease fluid protein-15 (GCDFP-15) (Figures 3(a)-3(c)).