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case_images: A: The histopathological appearance of the left eye corneal ulcer and acute keratitis with stromal infiltrate by acute polymorphonuclear cells (Original magnification x400 Hematoxylin & Eosin). B: The evisceration tissue showing areas of bone formation as part of phthisis bulbi changes (Original magnification x200 Hematoxylin & Eosin). C: The area of capillary proliferation within the retina and surrounding foamy histiocytes confirming the intraocular retinal capillary hemangioma (Original magnification x200 Hematoxylin & Eosin). D: The outline of the capillaries in the retinal hemangioma using endothelial cell marker (Original magnification x200 CD31).
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case_images: Histopathological studies revealed thick and irregular corneal epithelium and stroma with acute inflammatory cells, an adjacent area of necrosis, and an area of ulceration (Fig. 1A). However, adjacent to the choroid, large areas of fibrous tissue and bone formation were observed, representing fibrous and osseous metaplasia of the retinal pigment epithelium (RPE) (Fig. 1B). One focal area in the retina showed marked disruption and gliosis with a large vascular lesion consisting of retinal capillary blood vessels proliferation (Fig. 1C). The capillaries of the vascular lesion were outlined with immunohistochemical staining and expression of CD31 (Fig. 1D).
case_images: Timeline describing the steps of the patient's presentation and diagnosis. Retinal Capillary Hemangioma in a Pthisical Globe: Late sequelae in a case of Von Hippel-Lindau (VHL) disease presenting with endophthalmitis.
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