case_images: PMC4772936_01
case_images: A 5-mm orange-pink papule on the right frontal scalp.
case_images: dpa-0001-0029-g01.jpg
case_images: PMC4772936_01_dpa-0001-0029-g01.jpg
case_images: F1
case_images: A 12-year-old girl presented with a 1-year history of a slow-growing papule on her right frontal scalp (fig. 1).
case_images: Low power reveals numerous nests and fascicles of cells intersecting the collagen bundles of the superficial and deep reticular dermis. HE. x4.
case_images: dpa-0001-0029-g02.jpg
case_images: PMC4772936_01_dpa-0001-0029-g02.jpg
case_images: F2
case_images: Histopathologic examination revealed a diffuse proliferation of spindle and epithelioid cells within the superficial and deep reticular dermis, arranged in a nested and fascicular growth pattern (fig. 2, 3, 4).
case_images: The nests and fascicles are composed of large, oval to spindled cells with abundant amphophilic cytoplasm and little nuclear cytologic pleomorphism; occasional cells possess smudgy hyperchromatic nuclei. HE. x10.
case_images: dpa-0001-0029-g03.jpg
case_images: PMC4772936_01_dpa-0001-0029-g03.jpg
case_images: F3
case_images: Histopathologic examination revealed a diffuse proliferation of spindle and epithelioid cells within the superficial and deep reticular dermis, arranged in a nested and fascicular growth pattern (fig. 2, 3, 4).
case_images: The nests and fascicles are composed of large, oval to spindled cells with abundant amphophilic cytoplasm and little nuclear cytologic pleomorphism; occasional cells possess smudgy hyperchromatic nuclei. HE. x20.
case_images: dpa-0001-0029-g04.jpg
case_images: PMC4772936_01_dpa-0001-0029-g04.jpg
case_images: F4
case_images: Histopathologic examination revealed a diffuse proliferation of spindle and epithelioid cells within the superficial and deep reticular dermis, arranged in a nested and fascicular growth pattern (fig. 2, 3, 4).
case_images: Immunohistochemical staining positive for antibodies to NK1C3 (x20).
case_images: dpa-0001-0029-g05.jpg
case_images: PMC4772936_01_dpa-0001-0029-g05.jpg
case_images: F5
case_images: Immunohistochemical staining showed the tumor to be strongly positive for NK1C3 (fig. 5) and negative for S-100.