case_images: PMC6784618_01
case_images: Clinical photographs. (A, B) A mass with an old operation scar is present in the abdominal wall.
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case_images: LUQ of the abdomen (Fig. 1). Laboratory tests are non-specific.
case_images: A computed tomography scan shows and abdominal wall mass (in red circle).
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case_images: On computed tomography (CT), a 5x6-cm tumor was observed between the skin and subcutaneous tissue in the LLQ of the abdomen (Fig. 2).
case_images: Microscopic findings. The transformation from neurofibroma (left area) to malignant peripheral nerve sheath tumor (right area) is present (hematoxylin and eosin stain, x100).
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case_images: Histologic testing showed tissue with specific spindle cells that were longitudinal and wavy, transformed from neurofibroma with low cellularity to MPNST with increased cellularity and pleomorphic cells (Fig. 3).
case_images: Immunochemical findings. The tumor cells are weakly positive for S100 protein (A) and negative for H3K27me3 (B) (immunohistochemial stain, x200)
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case_images: On immunochemistry testing, an S100 protein test was weakly positive, and H3K27me3 staining was negative (Fig. 4); based on these results, we made a definite diagnosis of MPNST.