case_images: PMC11813640_01
case_images: (A) Sclerotic white plaques on the labia majora, with intermixed white papules. (B) Comparable sclerotic plaques were also observed in the perianal region.. Original image by the authors.
case_images: cureus-0017-00000077303-i01.jpg
case_images: PMC11813640_01_cureus-0017-00000077303-i01.jpg
case_images: FIG1
case_images: Similar lesions were noted in the perianal region (Figure 1).
case_images: Low-power view of the biopsy specimen from the labia majora.. Original image by the authors.
case_images: cureus-0017-00000077303-i02.jpg
case_images: PMC11813640_01_cureus-0017-00000077303-i02.jpg
case_images: FIG2
case_images: Histopathological analysis of a biopsy from the labia majora revealed mild hyperkeratosis, epidermal atrophy, and liquefactive degeneration of the basal layer (Figures 2, 3). The upper dermis showed homogenized collagen fibers and edema, while the deeper dermis exhibited thickened collagen bundles and inflammatory cell infiltration (Figures 2, 4).
case_images: Higher magnification of the dotted circular area in Figure 2, demonstrating a flattened epidermis (white arrow), focal liquefactive degeneration of the basal layer (black arrows), and homogenized collagen fibers in the superficial dermis.. Original image by the authors.
case_images: cureus-0017-00000077303-i03.jpg
case_images: PMC11813640_01_cureus-0017-00000077303-i03.jpg
case_images: FIG3
case_images: Histopathological analysis of a biopsy from the labia majora revealed mild hyperkeratosis, epidermal atrophy, and liquefactive degeneration of the basal layer (Figures 2, 3).
case_images: Higher magnification of the circled area in Figure 2, demonstrating pronounced thickened and inflated collagen bundles in the deeper dermis.. Original image by the authors.
case_images: cureus-0017-00000077303-i04.jpg
case_images: PMC11813640_01_cureus-0017-00000077303-i04.jpg
case_images: FIG4
case_images: The upper dermis showed homogenized collagen fibers and edema, while the deeper dermis exhibited thickened collagen bundles and inflammatory cell infiltration (Figures 2, 4).
case_images: Clinical response to topical steroid ointment. After six months of treatment with topical hydrocortisone butyrate, the lesion exhibited notable pigmentation (black arrows), accompanied by significant improvement in pruritus.. Original image by the authors.
case_images: cureus-0017-00000077303-i05.jpg
case_images: PMC11813640_01_cureus-0017-00000077303-i05.jpg
case_images: FIG5
case_images: After four months of treatment, the skin lesions showed partial hyperpigmentation, and by six months, most plaques had resolved into hyperpigmented patches (Figure 5).