case_images: PMC11335410_01
case_images: Transverse plane (a, b) and coronal plane (c) computed tomography (CT): observed pericardial effusion (red arrows) with relative hyperdensity of the collections and suspected cardiac tamponade.
case_images: CRIID2024-8877876.001.jpg
case_images: PMC11335410_01_CRIID2024-8877876.001.jpg
case_images: fig1
case_images: Computed tomography revealed bilateral pleural effusion and suggested the presence of cardiac tamponade caused by a substantial pericardial effusion (Figure 1).
case_images: Results of mNGS analysis on the patient's pericardial fluid. The sequenced gene fragment regions were widely distributed across different locations on the Rickettsia felis genome. This indicated that the detected reads did not originate from single-fragmented DNA pieces through repeated sequencing but rather came from the entire genome, thus proving the presence of Rickettsia felis in the sample.
case_images: CRIID2024-8877876.002.jpg
case_images: PMC11335410_01_CRIID2024-8877876.002.jpg
case_images: fig2
case_images: Our mNGS results indicated the presence of Rickettsia felis (275 reads) that accounted for 2.18% of nucleotide sequence coverage and showed 62.29% relative abundance in the pericardial fluid (Table 1, Figure 2) but was not detected in the blood.