case_images: PMC10485270_01
case_images: (A) Pedigree of the extended family with no ALS history; (B) Sanger sequencing results of family members. The index patient is heterozygous for c.140A>G mutation, while neither of the asymptomatic parents carries the mutation, confirming the de novo occurrence of the mutation.
case_images: fgene-14-1208673-g001.jpg
case_images: PMC10485270_01_fgene-14-1208673-g001.jpg
case_images: F1
case_images: There are no similar complaints in the family and no previous disease history (Figure 1A).
case_images: PMC10485270_02
case_images: PMC10485270_03