case_images: PMC10493324_01
case_images: Before anterior chamber washout and intravitreal methotrexate, bilateral pseudohypopyon.
case_images: fonc-13-1237204-g001.jpg
case_images: PMC10493324_01_fonc-13-1237204-g001.jpg
case_images: f1
case_images: Because of poor patient cooperation due to age, pain, and photophobia, it was not possible to measure the visual acuity and to find details on the slit lamp, so a physical examination under general anesthesia was performed, finding a pseudohypopyon of 4 mm and 1 mm on the right and left eyes, respectively ( Figure 1 ), an IOP of 30 mmHg in the right eye and 14 mmHg in the left eye, and vitreous haze on both eyes ( Figure 2 ).
case_images: Before intravitreal methotrexate, bilateral vitreous haze.
case_images: fonc-13-1237204-g002.jpg
case_images: PMC10493324_01_fonc-13-1237204-g002.jpg
case_images: f2
case_images: Because of poor patient cooperation due to age, pain, and photophobia, it was not possible to measure the visual acuity and to find details on the slit lamp, so a physical examination under general anesthesia was performed, finding a pseudohypopyon of 4 mm and 1 mm on the right and left eyes, respectively ( Figure 1 ), an IOP of 30 mmHg in the right eye and 14 mmHg in the left eye, and vitreous haze on both eyes ( Figure 2 ).
case_images: Left, aqueous humor biopsy before intravitreal methotrexate that reported atypical immature cells compatible with blasts, >500 blasts per high-power field. Right, aqueous humor biopsy after intravitreal methotrexate, five blasts per high-power field at the third week of treatment.
case_images: fonc-13-1237204-g003.jpg
case_images: PMC10493324_01_fonc-13-1237204-g003.jpg
case_images: f3
case_images: In the aqueous humor biopsy, >500 blasts were reported per high-power field ( Figure 3 ).
case_images: After anterior chamber washout and intravitreal methotrexate, no pseudohypopyon.
case_images: fonc-13-1237204-g004.jpg
case_images: PMC10493324_01_fonc-13-1237204-g004.jpg
case_images: f4
case_images: On ophthalmological examination, there was no pseudohypopyon ( Figure 4 ), a marked decrease in IOP, and a progressive decrease in the vitreous haze ( Figure 5 ) until the fundus could be visualized without evidence of lesions.
case_images: After anterior chamber washout and intravitreal methotrexate. Improvement of the bilateral vitreous haze.
case_images: fonc-13-1237204-g005.jpg
case_images: PMC10493324_01_fonc-13-1237204-g005.jpg
case_images: f5
case_images: On ophthalmological examination, there was no pseudohypopyon ( Figure 4 ), a marked decrease in IOP, and a progressive decrease in the vitreous haze ( Figure 5 ) until the fundus could be visualized without evidence of lesions.
case_images: Treatment timeline.
case_images: fonc-13-1237204-g006.jpg
case_images: PMC10493324_01_fonc-13-1237204-g006.jpg
case_images: f6