case_images: PMC10601682_01
case_images: Histopathological findings. a Tumor cell proliferation with solid and trabecular architecture with focal necrosis, consistent with an AC (H&E stain; x200). b Tumor cells stain diffusely for synaptophysin (x400).
case_images: crn-2023-0015-0001-529846_F01.jpg
case_images: PMC10601682_01_crn-2023-0015-0001-529846_F01.jpg
case_images: F1
case_images: Histology and immunohistochemistry showed tumor cell proliferation with solid and trabecular architecture, focal necrosis, and diffuse positivity for synaptophysin consistent with an AC (shown in Fig. 1).
case_images: Coronal FLAIR sequences show a hypersignal in the left and right temporal lobes as well as a cortico-subcortical atrophy of both temporal lobes, which are subtle in the baseline MRI (a) and increase on a 13-month (b) and a 21-month (c) follow-up MRI.
case_images: crn-2023-0015-0001-529846_F02.jpg
case_images: PMC10601682_01_crn-2023-0015-0001-529846_F02.jpg
case_images: F2
case_images: Brain MRI revealed bilateral mesial temporal and insular T2 hyperintensities predominating on the left side, in addition to extensive frontal subcortical vascular leukoencephalopathy (shown in Fig. 2a). Brain MRI showed a notable regression of bilateral mesial temporal lobe hyperintensities (Fig. 2b). Two years after treatment, cognitive performance remained stable despite atrophy of the mesial temporal lobe (shown in Fig. 2c).