case_images: PMC11375247_01
case_images: PMC11375247_02
case_images: - Blood counts and supportive medications from start of induction for case #1. Aza = azacitidine; ven = venetoclax; EPO = epoetin; BMBx = bone marrow biopsy; CR = complete remission.
case_images: gr1.jpg
case_images: PMC11375247_02_gr1.jpg
case_images: fig0001
case_images: The hemoglobin nadir was 66 g/L on Day 22, while the platelet nadir was 28 x 109/L on Day 15 (Fig. 1).
case_images: - Blood counts and supportive medications from start of induction for case #2. HU = hydroxyurea; ATO = arsenic trioxide; ATRA = all-trans retinoic acid; DBPOI = darbepoetin; BMBx = bone marrow biopsy; CR = complete remission.
case_images: gr2.jpg
case_images: PMC11375247_02_gr2.jpg
case_images: fig0002
case_images: ATO 0.15 mg/kg/day IV was initiated on Day 3. ATO was held at various points during induction (Fig. 2) for leukocytosis to minimize differentiation syndrome risk. The Hgb nadir was 44 g/L on Day 19, and platelet nadir was 9 x 109/L on Day 3, with a secondary platelet nadir of 28 x 109/L on Day 17 (Fig. 2).