case_images: PMC10601863_01
case_images: Photographs of the left eye before and after treatment. a At the first visit, superficial multi-lobulated epithelial infiltration of 4 x 4 mm located at the inferior cornea. An irregular epithelial surface, mild anterior chamber inflammation with a small hypopyon, and moderate conjunctival injection were noted. b Slit beam biomicroscopy revealed irregular multi-lobulated superficial corneal infiltration (arrow). c Fluorescein stain picture showed positive fluorescein epithelial staining at the irregular surface of the lower cornea. d After 3 weeks of medical treatment, the edge of lesions became flat and well demarcated, with an irregular superficial corneal epithelial healing.
case_images: cop-2023-0014-0001-533906_F01.jpg
case_images: PMC10601863_01_cop-2023-0014-0001-533906_F01.jpg
case_images: F1
case_images: There was an irregular epithelial surface, mild anterior chamber inflammation with small hypopyon, and moderate ciliary injection (shown in Fig. 1a, b). The edge of lesion became flat and well-demarcated infiltration, with irregular superficial corneal epithelial healing (shown in Fig. 1c, d).
case_images: a, b Numerous dry and chalky white colonies of Nocardia spp. grew up on blood agar and Lowenstein-Jensen agar. c Gram-positive bacilli with filamentous branching found in Gram stain x100. d modified acid-fast stain demonstrated partial eosinophilic filamentous pathogens x100.
case_images: cop-2023-0014-0001-533906_F02.jpg
case_images: PMC10601863_01_cop-2023-0014-0001-533906_F02.jpg
case_images: F2
case_images: However, bacterial culture on blood agar after 5 days demonstrated dry and chalky white colonies (shown in Fig. 2a), and colonies of similar appearance grew on the Lowenstein-Jensen media (shown in Fig. 2b). Gram stain and modified acid-fast stain of the specimens derived from white colonies exhibited Gram-positive branched filamentous bacilli (shown in Fig. 2c) and partial eosinophilic filamentous organisms (shown in Fig. 2d), respectively.