case_images: PMC3087438_01
case_images: Thoracic X-ray: (a) on day 176, it could be observed a small pulmonary node behind the fifth right thoracic rib (arrow); (b) 3 months, later the pulmonary node was much larger and became cavitated.
case_images: CRIM2011-830769.001.jpg
case_images: PMC3087438_01_CRIM2011-830769.001.jpg
case_images: fig1
case_images: On the thoracic X-ray (Figure 1(a)) there was small pulmonary node that gradually enlarged so he forwarded a thoracic CT, on day 192 which revealed a cavitated lesion on the right superior pulmonary lobe. However, he maintained persistent fever and the pulmonary cavitated nodule continued to get worse on thoracic X-ray image (Figure 1(b)).
case_images: CT scan of the perinasal sinuses: infiltrative lesion of the perinasal sinuses that exerts compression on the right optic nerve.
case_images: CRIM2011-830769.002.jpg
case_images: PMC3087438_01_CRIM2011-830769.002.jpg
case_images: fig2
case_images: CT scan of the perinasal sinuses revealed an infiltrative lesion of the perinasal sinuses with ethmoiditis and compression of the right optic nerve (Figure 2).
case_images: Ethmoiditis due to Scedosporium apiospermum. (a) Mucosa lined by respiratory type epithelium with intense inflammatory reaction (hematoxylin and eosin [H&E] staining, magnification x100); (b) higher magnification (x400) of (a) it can be identified numerous epithelioid granulomas and multinucleated giant cells; (c) partially destroyed bone tissue and numerous fungal hyphae (H&E staining, magnification x100); (d) morphologically the fungal hyphae resemble Aspergillus spp. (H&E, magnification x400); (e) bone tissue destruction by fungal hyphae (PAS staining, magnification x100); (f) the main host response is a mixed neutrophilic and monocytic infiltrate (PAS staining, magnification x400).
case_images: CRIM2011-830769.003.jpg
case_images: PMC3087438_01_CRIM2011-830769.003.jpg
case_images: fig3
case_images: Pathology analysis showed signs of ethmoiditis and numerous fungal hyphae (Figures 3(a)-3(f)).