case_images: PMC3961349_01
case_images: Positron emission tomography-computed tomography demonstrated a hypermetabolic lesion (standardized uptake value, 12.8) in the interspace between the liver and stomach. There was no additional fludeoxyglucose (18F) uptake, which indicated a primary site in other organs.
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case_images: PET/CT and maximum intensity projection images are shown in Fig. 1. PET/CT identified a hypermetabolic lesion in the interspace between the liver and stomach.
case_images: Intraoperative fast pathological sections revealed that the tumor tissues were composed of nidulant, multi-mitotic cells and necrosis, which was reported as a squamous cell carcinoma. (Hematoxylin and eosin staining; magnification, x100).
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case_images: Intraoperative fast pathological sections revealed that the tumor tissues were composed of nidulant, multi-mitotic cells and necrosis, which were identified as SCC (Fig. 2); therefore, the tumor was resected and a proximal gastrectomy was performed.
case_images: Tumor cells were observed in the (A) gastric serosa fibrous tissue, (B) lamina muscularis and (C) submucosa. (Hematoxylin and eosin staining; magnification, x100).
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case_images: Histopathology revealed that the SCC infiltrated into the serosal fibrous tissue, lamina muscularis and submucosa of the gastric wall (Fig. 3A-C); however, there was no cancer cell infiltration into the mucosa.
case_images: Strong expression of cytokeratin 5/6 observed via immunohistochemical staining. (Hematoxylin and eosin staining; magnification, x200).
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case_images: The immunohistochemical staining was positive for cytokeratin (CK)5/6, p63, CKpan and glutathione S-transferase pi (Figs. 4-7), and negative for cluster of differentiation (CD)56, CDX-2, chromogranin A, CK20, CK7, S100, Syn, Villin, P-glycoprotein, epidermal growth factor receptor, topoisomerase II and p53.
case_images: Immunohistochemical staining identified p63 positivity in the tumor cells. (Hematoxylin and eosin staining; magnification, x200).
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case_images: The immunohistochemical staining was positive for cytokeratin (CK)5/6, p63, CKpan and glutathione S-transferase pi (Figs. 4-7), and negative for cluster of differentiation (CD)56, CDX-2, chromogranin A, CK20, CK7, S100, Syn, Villin, P-glycoprotein, epidermal growth factor receptor, topoisomerase II and p53.
case_images: Immunohistochemical staining identified cytokeratin pan positivity in the tumor cells. (Hematoxylin and eosin staining; magnification, x200).
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case_images: The immunohistochemical staining was positive for cytokeratin (CK)5/6, p63, CKpan and glutathione S-transferase pi (Figs. 4-7), and negative for cluster of differentiation (CD)56, CDX-2, chromogranin A, CK20, CK7, S100, Syn, Villin, P-glycoprotein, epidermal growth factor receptor, topoisomerase II and p53.
case_images: Positive glutathione S-transferase pi immunostaining was observed in the neoplastic cells. (Hematoxylin and eosin staining; magnification, x200).
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case_images: The immunohistochemical staining was positive for cytokeratin (CK)5/6, p63, CKpan and glutathione S-transferase pi (Figs. 4-7), and negative for cluster of differentiation (CD)56, CDX-2, chromogranin A, CK20, CK7, S100, Syn, Villin, P-glycoprotein, epidermal growth factor receptor, topoisomerase II and p53.
case_images: Ki-67 proliferation index, ~50%. (Hematoxylin and eosin staining; magnification, x200).
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case_images: The Ki-67 proliferation index was ~50% (Fig. 8).