case_images: PMC9938668_01
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: PMC9938668_02
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: PMC9938668_03
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: Sequencing results and evolutionary tree for case 3, 4, 5. (A) Genome coverage of Case: Mapping of the 864 mNGS reads from Chlamydia psittaci to reference genome. (B) Case: Mapping of the 102 reads. (C) Case 5: Mapping of the 2 reads. (D) Electrophoresis of ompA gene. PCR product sequencing showed that sequences ~1000 bp in size were obtained from all 3 samples. These 3 bands correspond to the expected fragment size. (E) Phylogenetic tree of ompA gene. Coverage: the percentage of the genome covered by reads over 1x. Average depth: average sequencing depth. The number of bases aligned to the reference genome divided by the length of the genome.
case_images: IDR-16-869-g0002.jpg
case_images: PMC9938668_06_IDR-16-869-g0002.jpg
case_images: f0002
case_images: All three samples were greater than 1000 bp in size (Figure 2D). All C. psittaci-positive samples shared the highest ompA similarity with C. psittaci strain 41A12, which belongs to the B genotype(Figure 2E).
case_images: PMC9938668_04
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: Sequencing results and evolutionary tree for case 3, 4, 5. (A) Genome coverage of Case: Mapping of the 864 mNGS reads from Chlamydia psittaci to reference genome. (B) Case: Mapping of the 102 reads. (C) Case 5: Mapping of the 2 reads. (D) Electrophoresis of ompA gene. PCR product sequencing showed that sequences ~1000 bp in size were obtained from all 3 samples. These 3 bands correspond to the expected fragment size. (E) Phylogenetic tree of ompA gene. Coverage: the percentage of the genome covered by reads over 1x. Average depth: average sequencing depth. The number of bases aligned to the reference genome divided by the length of the genome.
case_images: IDR-16-869-g0002.jpg
case_images: PMC9938668_06_IDR-16-869-g0002.jpg
case_images: f0002
case_images: All three samples were greater than 1000 bp in size (Figure 2D). All C. psittaci-positive samples shared the highest ompA similarity with C. psittaci strain 41A12, which belongs to the B genotype(Figure 2E).
case_images: PMC9938668_05
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: Sequencing results and evolutionary tree for case 3, 4, 5. (A) Genome coverage of Case: Mapping of the 864 mNGS reads from Chlamydia psittaci to reference genome. (B) Case: Mapping of the 102 reads. (C) Case 5: Mapping of the 2 reads. (D) Electrophoresis of ompA gene. PCR product sequencing showed that sequences ~1000 bp in size were obtained from all 3 samples. These 3 bands correspond to the expected fragment size. (E) Phylogenetic tree of ompA gene. Coverage: the percentage of the genome covered by reads over 1x. Average depth: average sequencing depth. The number of bases aligned to the reference genome divided by the length of the genome.
case_images: IDR-16-869-g0002.jpg
case_images: PMC9938668_06_IDR-16-869-g0002.jpg
case_images: f0002
case_images: All three samples were greater than 1000 bp in size (Figure 2D). All C. psittaci-positive samples shared the highest ompA similarity with C. psittaci strain 41A12, which belongs to the B genotype(Figure 2E).
case_images: PMC9938668_06
case_images: Chlamydia psittaci appearance on chest CT in Cases 1-6 (A-F) on the day of admission (left) and after treatment (right).
case_images: IDR-16-869-g0001.jpg
case_images: PMC9938668_06_IDR-16-869-g0001.jpg
case_images: f0001
case_images: Chest CT images obtained on the second day of hospitalization showed an air bronchogram in the right subpleural area with GGOs and halo signs (Figure 1F, left). After 6 days of doxycycline treatment, the patient's right upper lobe lesions improved and were totally absorbed (Figure 1F, right).
case_images: Sequencing results and evolutionary tree for case 3, 4, 5. (A) Genome coverage of Case: Mapping of the 864 mNGS reads from Chlamydia psittaci to reference genome. (B) Case: Mapping of the 102 reads. (C) Case 5: Mapping of the 2 reads. (D) Electrophoresis of ompA gene. PCR product sequencing showed that sequences ~1000 bp in size were obtained from all 3 samples. These 3 bands correspond to the expected fragment size. (E) Phylogenetic tree of ompA gene. Coverage: the percentage of the genome covered by reads over 1x. Average depth: average sequencing depth. The number of bases aligned to the reference genome divided by the length of the genome.
case_images: IDR-16-869-g0002.jpg
case_images: PMC9938668_06_IDR-16-869-g0002.jpg
case_images: f0002
case_images: All three samples were greater than 1000 bp in size (Figure 2D). All C. psittaci-positive samples shared the highest ompA similarity with C. psittaci strain 41A12, which belongs to the B genotype(Figure 2E).
case_images: Bronchoscope imagings of all cases after hospitalization. All patients showed hyperemia and swelling of bronchial mucosa, significant exudation in the bronchi, and a little of white secretions in the segmental bronchi.
case_images: IDR-16-869-g0003.jpg
case_images: PMC9938668_06_IDR-16-869-g0003.jpg
case_images: f0003
case_images: Supplementary. Significant congestion in the bronchial lumen of the lung was observed in all patients in fiberoptic bronchoscopy (Figure 3).