case_images: PMC5864713_01
case_images: A nodule with large localized areas of necrosis under the thyroid capsule (H&E, x40).
case_images: NCI-5-67-g001.jpg
case_images: PMC5864713_01_NCI-5-67-g001.jpg
case_images: F1
case_images: Focal papillary proliferations around large necrosis areas (H&E, x100).
case_images: NCI-5-67-g002.jpg
case_images: PMC5864713_01_NCI-5-67-g002.jpg
case_images: F2
case_images: Thyrocytes of papillary carcinoma with a large oncocytic cytoplasm aligned around the fibrovascular core (H&E, x400).
case_images: NCI-5-67-g003.jpg
case_images: PMC5864713_01_NCI-5-67-g003.jpg
case_images: F3
case_images: Extensive strong positivity with cytokeratin 19 and papillary structures (Immunohistochemistry, x400).
case_images: NCI-5-67-g004.jpg
case_images: PMC5864713_01_NCI-5-67-g004.jpg
case_images: F4
case_images: Focal weak positive staining with HBME 1 (Immunohistochemistry, x400).
case_images: NCI-5-67-g005.jpg
case_images: PMC5864713_01_NCI-5-67-g005.jpg
case_images: F5
case_images: No staining with galectin-3 was observed (Immunohistochemistry, x400).
case_images: NCI-5-67-g006.jpg
case_images: PMC5864713_01_NCI-5-67-g006.jpg
case_images: F6
case_images: Cytologic examination revealed presence of mild hypochromia with large oncocytic morphology, focal overlapping, and infrequent intranuclear inclusion (PAP EA 50, x400).
case_images: NCI-5-67-g007.jpg
case_images: PMC5864713_01_NCI-5-67-g007.jpg
case_images: F7
case_images: Magnetic Resonance Imaging (MRI) showed a 2.5x1.5-cm mass lesion in the right superior mesencephalon.
case_images: NCI-5-67-g008.jpg
case_images: PMC5864713_01_NCI-5-67-g008.jpg
case_images: F8
case_images: During MRI at our center (Fig. 8), a mass was detected in the brain stem. "Astrocytoma," as a 2nd synchronous primary tumor, was detected in the patient who underwent surgery at an external center at the patient's request.