case_images: PMC10199319_01
case_images: V. vulnificus infection in the right forearm. (a) On the first day of admission, the right forearm was swollen and tenderness. (b) On the second day of admission, the scope was enlarged and tension blisters. (c) Swelling and blisters disappear when transferred out of ICU. (d) One month after discharge, the right forearm was recovered as before.
case_images: j_biol-2022-0584-fig001.jpg
case_images: PMC10199319_01_j_biol-2022-0584-fig001.jpg
case_images: j_biol-2022-0584_fig_001
case_images: Later, the swelling gradually spread and became painful; half a day before admission the patient began to develop asthma and dyspnea, which gradually worsened; physical examination into the emergency room: body temperature 101.3 degrees Fahrenheit, SPO290%, blood pressure 78/54 mmHg (1 mmHg = 0.133 kPa), blurred consciousness, no stab wounds or injuries, high skin temperature on the right forearm and back of the hand, sunken redness and swelling, obvious tenderness (Figure 1a), GCS score 12, qSOFA score 3. On the second day after admission, the focus of infection spread to the proximal end of the heart, and tension blisters appeared (Figure 1b). Patients were transferred to intensive care unit (ICU) on the ninth day (Figure 1c) and recovered well 1 month after discharge (Figure 1d).
case_images: mNGS total sequence coverage of V. vulnificus. (a) The total coverage rate of V. vulnificus in blood samples is 4.80%. (b) The total coverage rate of V. vulnificus in secretion was 26.02%.
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case_images: PMC10199319_01_j_biol-2022-0584-fig002.jpg
case_images: j_biol-2022-0584_fig_002
case_images: There was no indication of incision in surgical consultation. mNGS results on the second day of admission: the sequence number of V. vulnificus in secretion samples was 42,501, the relative abundance was 89.88%, the total coverage rate was 26.02%, and the sequence number, relative abundance, and total coverage rate of V. vulnificus in blood samples were 6,523, 52.07%, and 4.80% respectively (Figure 2).