case_images: PMC7443985_01
case_images: Serum creatinine (mg/dL) versus months after presentation with SRC.. BP: blood pressure; mg/dL: milligrams/deciliter; DBP: diastolic blood
  pressure; H: hospitalization for renal crisis; mmHg: millimeters of mercury;
  RBx: renal biopsy; SBP: systolic blood pressure; SBx: skin biopsy; sCr:
  serum creatinine; SRC: scleroderma renal crisis. Black arrow:
  corticosteroids 1 mg/kg; Red arrow: bevacizumab 1.25 mg injections x 2;
  Green arrow: renal replacement therapy:hemodialysis.
case_images: 10.1177_2050313X20952650-fig2.jpg
case_images: PMC7443985_01_10.1177_2050313X20952650-fig2.jpg
case_images: fig2-2050313X20952650
case_images: Figure 2 shows the trends of serum creatinine, systolic blood pressure, and diastolic blood pressures for this case.
case_images: Features of active thrombotic microangiopathy on renal biopsy: (a) arteries
  with near-complete luminal occlusion by fibrointimal proliferation (arrows)
  and adjacent ischemic tubulopathy (periodic acid Schiff stain, 100x); (b)
  artery with mucoid intimal hyperplasia (arrow) (trichrome stain 200x); (c)
  artery with "onion skin" change (trichrome stain 400x); and (d) "bloodless"
  glomerulus (H&E stain, 400x).
case_images: 10.1177_2050313X20952650-fig3.jpg
case_images: PMC7443985_01_10.1177_2050313X20952650-fig3.jpg
case_images: fig3-2050313X20952650
case_images: The patient's renal biopsy (Figure 3) contained 57 glomeruli (1 globally sclerotic) and light microscopy demonstrated arteries with near-complete luminal occlusion by fibrointimal proliferation and adjacent ischemic tubulopathy.