case_images: PMC4712428_01
case_images: The patient's swollen left knee (A) and vasculitic lesions on the lower limb (B).
case_images: kjim-31-1-194f1.jpg
case_images: PMC4712428_01_kjim-31-1-194f1.jpg
case_images: f1-kjim-31-1-194
case_images: A 35-year-old man presented with arthralgia in the large joints, a palpable purpuric rash on both legs, swelling of the left knee (Fig. 1), difficulty swallowing, and epigastric discomfort for 2 weeks.
case_images: Light (A: H&E, x200; B: PAS, x200) and immunofluorescence (C) microscopy of the renal biopsy, and light microscopic images (D: H&E, x400) of the skin biopsy. (A) and (B) show mesangial cellular proliferation (arrows), and increased mesangial matrix production, respectively. (C) depicts mesangial deposits of immunoglobulin A. (D) shows perivascular polymorphic neutrophil infiltration and extravasated erythrocytes (arrows).
case_images: kjim-31-1-194f2.jpg
case_images: PMC4712428_01_kjim-31-1-194f2.jpg
case_images: f2-kjim-31-1-194
case_images: A renal biopsy was compatible with IgA nephropathy (Fig. 2).