case_images: PMC4357411_01
case_images: Computed tomography urography. (A) Images taken three months before the surgery demonstrate a 4.9-cm-sized right seminal vesicle cyst (arrowhead) and an exophytic tumor measuring up to 3 cm (arrow). (B) Images taken three months later show a 4.7-cm-sized seminal vesicle cyst (arrowhead) with an enlarged mass (arrow) bulging to the left prostate gland (6.1 cm).
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case_images: Computed tomography (CT) urography revealed hypoplastic change in the right kidney, a 4.9-cm-sized right seminal vesicle cyst with a thickened wall, and benign prostate hyperplasia (Fig. 1A). CT urography and magnetic resonance imaging demonstrated a bulging mass at the left prostate gland, which had increased in size compared with images taken three months previous (Fig. 1B).
case_images: Histopathologic findings of the right seminal vesicle cyst. The specimen shows squamous metaplasia (insert), glandular tissues (A), and a poorly differentiated carcinoma (B).
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case_images: Under the microscope, squamous metaplasia was observed in the seminal vesicle cyst lining (Fig. 2A). Microscopically observed, the tumor was a poorly differentiated carcinoma (Fig. 2B).
case_images: Immunohistochemistry and histochemical staining for phenotyping of the carcinoma. Tumor cells are positive for p63 (A), and negative for cytokeratin 7 (B), cytokeratin 20 (C), and carcinoembryonic antigen (D). Vimentin shows focal positivity in macrophages (E), and periodic acid-Schiff staining is positive for mucin (F).
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case_images: Immunohistochemical analysis of the tumor was positive for p63 (Fig. 3A) and negative for cytokeratin 7 (Fig. 3B), cytokeratin 20 (Fig. 3C), and carcinoembryonic antigen (Fig. 3D). Although the specimen displayed some immunoactivity for vimentin (Fig. 3E), the staining was positive in macrophages, as reported in murine seminal vesicle carcinoma. Histochemical studies (periodic acid-Schiff [PAS] and mucicarmine) were positive for mucin (Fig. 3F).