case_images: PMC10895986_01
case_images: SRFMM tongue ulcer in patient 2. (A) shows a small ulcer at 8 months of age. (B) shows multiple ulcers at 1.2 year of age.
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case_images: PMC10895986_01_NSS-16-207-g0001.jpg
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case_images: The tongue biting event occurred to the four male infants at the age of 0.5-2 years along with sudden scream 1-20 times per night, crying, breast-feed difficulty and severe ulcers on the tongue (Figure 1).
case_images: Electroclinical features of SRFMM in patient 1. (A) showed a sudden EMG burst of bilateral masticatory muscle followed by arousals at NREM stage 3 period during video-EEG monitoring. Red arrow indicates EMG bursts over bilateral masseter. (B-D) showed clinical manisfestations of crying and limbs lifting during SRFMM episode.
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case_images: PMC10895986_01_NSS-16-207-g0002.jpg
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case_images: SRFMM were recorded during the whole video-EEG, with 58 (93.5%) presented in non-rapid eye movement (NREM) sleep (35 in NREM 1, 21 in NREM 2 sleep, 2 in NREM 3 sleep) and 4 (6.5%) in tonic rapid eye movement (REM) sleep. Synchronized video-EEG disclosed a mouth movement, or sudden mouth closing which occasionally were triggered by sound or touch and always followed by limbs lifting and crying in infants (Figure 2).