case_images: PMC4331673_01
case_images: Firmness and marked increase in size of the right breast as seen on presenting physical examination.
case_images: fonc-05-00026-g001.jpg
case_images: PMC4331673_01_fonc-05-00026-g001.jpg
case_images: F1
case_images: She developed a recurrent fluid collection involving her right breast (Figure 1).
case_images: Effusion fluid (seroma). Anaplastic large cells present in the effusion surrounding the breast implant. Anaplastic large cells also involve the breast implant capsule (not shown). Immunohistochemical staining shows anaplastic large-cell lymphoma T-cell type.
case_images: fonc-05-00026-g002.jpg
case_images: PMC4331673_01_fonc-05-00026-g002.jpg
case_images: F2
case_images: On histopathologic analysis, anaplastic large-cell lymphoma (ALCL), anaplastic lymphoma kinase (ALK)-negative was demonstrated in the fibrous capsule, cystic fluid, and axillary lymph nodes (Figures 2 and 3).
case_images: Axillary lymph node. Axillary lymph node of the same patient shows large atypical cells involving the sinusoidal and lymphatic space, consistent with anaplastic large cells involving the lymph node.
case_images: fonc-05-00026-g003.jpg
case_images: PMC4331673_01_fonc-05-00026-g003.jpg
case_images: F3
case_images: On histopathologic analysis, anaplastic large-cell lymphoma (ALCL), anaplastic lymphoma kinase (ALK)-negative was demonstrated in the fibrous capsule, cystic fluid, and axillary lymph nodes (Figures 2 and 3).
case_images: Right axillary lymphadenopathy demonstrated on axial and coronal PET scan images with abnormal FDG avidity (A,B) and coronal CT images with contrast (C,D).
case_images: fonc-05-00026-g004.jpg
case_images: PMC4331673_01_fonc-05-00026-g004.jpg
case_images: F4
case_images: Imaging with CT and PET scans demonstrated residual right axillary lymphadenopathy with FDG avidity, as illustrated in Figure 4.
case_images: Coronal CT slice of treatment plan showing isodose lines and contoured axillary nodal volume.
case_images: fonc-05-00026-g005.jpg
case_images: PMC4331673_01_fonc-05-00026-g005.jpg
case_images: F5
case_images: The axilla levels 1-3 were contoured and a lightly weighted posterior axillary field was used to bring the volume up to the prescription dose (Figure 5).