case_images: PMC11736479_01
case_images: Imaging characteristics of the hepatic lesion at the time of admission. A-C: Contrast-enhanced computed tomography scans in the venous phase demonstrated a lesion in the hepatic hilum, specifically in segment IV, with features suggestive of biliary involvement and invasion of the gallbladder; D: Magnetic resonance imaging also revealed similar characteristics.
case_images: 101664-g001.jpg
case_images: PMC11736479_01_101664-g001.jpg
case_images: F1
case_images: Further imaging with contrast-enhanced computed tomography (CT) and magnetic resonance imaging of the liver (Figure 1) demonstrated a mass in the hepatic hilum, particularly involving segment IV, raising suspicion for intrahepatic cholangiocarcinoma with possible invasion into the gallbladder.
case_images: Marked eosinophil infiltration observed on a hematoxylin and eosin-stained liver biopsy specimen. The biopsy showed dense infiltration of inflammatory cells, including lymphocytes and a significant number of eosinophils (orange arrows), in the periportal and lobular areas at various magnifications. A: 4 x magnification; B and C: 10 x magnification; D: 40 x magnification. No evidence of tumor tissue nor of malignant lesions was observed.
case_images: 101664-g002.jpg
case_images: PMC11736479_01_101664-g002.jpg
case_images: F2
case_images: After a comprehensive review by the multidisciplinary tumor board, a percutaneous core needle biopsy of the liver was performed, which showed acute inflammation in the portal tracts extending into the lobules, with marked eosinophilic infiltration and no evidence of malignancy (Figure 2).