case_images: PMC4281457_01
case_images: Preoperative CT scan brain showing a calcified lesion in the right temporoparietal region.
case_images: CRIM2014-175679.001.jpg
case_images: PMC4281457_01_CRIM2014-175679.001.jpg
case_images: fig1
case_images: CT scan showed a contrast enhancing isodense space occupying lesion with areas of calcification in right frontal cortex with surrounding edema (Figure 1).
case_images: Gross post-op specimen.
case_images: CRIM2014-175679.002.jpg
case_images: PMC4281457_01_CRIM2014-175679.002.jpg
case_images: fig2
case_images: Few areas of calcification are also seen (Figure 2).
case_images: 10x with mitosis.
case_images: CRIM2014-175679.003.jpg
case_images: PMC4281457_01_CRIM2014-175679.003.jpg
case_images: fig3
case_images: Hematoxylin and eosin stained tissue sections revealed a highly cellular neoplasm composed of predominantly spindle shaped cells with pleomorphic oval to elongated hyperchromatic nuclei (Figure 3).
case_images: SMA.
case_images: CRIM2014-175679.004.jpg
case_images: PMC4281457_01_CRIM2014-175679.004.jpg
case_images: fig4
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: GFAP.
case_images: CRIM2014-175679.005.jpg
case_images: PMC4281457_01_CRIM2014-175679.005.jpg
case_images: fig5
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: Mgen.
case_images: CRIM2014-175679.006.jpg
case_images: PMC4281457_01_CRIM2014-175679.006.jpg
case_images: fig6
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: PAS.
case_images: CRIM2014-175679.007.jpg
case_images: PMC4281457_01_CRIM2014-175679.007.jpg
case_images: fig7
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: S100.
case_images: CRIM2014-175679.008.jpg
case_images: PMC4281457_01_CRIM2014-175679.008.jpg
case_images: fig8
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: EMA.
case_images: CRIM2014-175679.009.jpg
case_images: PMC4281457_01_CRIM2014-175679.009.jpg
case_images: fig9
case_images: Immunostaining for S100, epithelial membrane antigen, was found to be negative and glial fibrillary acidic protein was scanty positive; Ki67 proliferation index was 10-15% and P 53 protein was positive (Figures 4, 5, 6, 7, 8, and 9).
case_images: Post-op CT scan brain with residual disease.
case_images: CRIM2014-175679.010.jpg
case_images: PMC4281457_01_CRIM2014-175679.010.jpg
case_images: fig10
case_images: The patient was given external beam radiotherapy 66 Gy at 2 Gy in 33 fractions and 6 cycles of chemotherapy with temozolomide 200 mg per day for 5 days every 28 days (Figure 10). The post-treatment MRI scan showed a residual focal area of brain edema and granulomatous calcified lesion with reactivation 2.5 x 2.5 cm; the lesion is hypointense in T1W and hyper in T2W (Figure 10).
case_images: CT scan residual tumor 2012.
case_images: CRIM2014-175679.011.jpg
case_images: PMC4281457_01_CRIM2014-175679.011.jpg
case_images: fig11
case_images: He is on regular follow-up with us and has survived for 30 months (Figures 11 and 12).
case_images: CT scan brain with residual tumor in the right temporoparietal region May 2014.
case_images: CRIM2014-175679.012.jpg
case_images: PMC4281457_01_CRIM2014-175679.012.jpg
case_images: fig12
case_images: He is on regular follow-up with us and has survived for 30 months (Figures 11 and 12).