case_images: PMC11096462_01
case_images: Heinrich Max Runge (1849- 1909), a German obstetrician and gynecologist who was the first to describe a histologically proven case of spinal metastases secondary to thyroid cancer.The image was taken from an open source: : Runge,_Max_Heinrich.jpg. The first page of the article entitled "Tumor des Atlas und Epistropheus bei einer Schwangeren". The paper was published in "Archiv fur pathologische Anatomie und Physiologie und fur klinische Medicin" in March 1876.
case_images: fendo-15-1354750-g002.jpg
case_images: PMC11096462_01_fendo-15-1354750-g002.jpg
case_images: f2
case_images: Max Runge described a case of what he believed was primary bone cancer with "little-observed and remarkable complex of symptoms, by the complication of pregnancy" in a 41-year-old woman ( Figure 2 ).
case_images: The original illustration of the metastatic tumor involving the C1 and C2 vertebrae secondary to thyroid carcinoma, published by Max Runge in 1876.
case_images: fendo-15-1354750-g003.jpg
case_images: PMC11096462_01_fendo-15-1354750-g003.jpg
case_images: f3
case_images: Microscopic examination of the thyroid does not yield anything suspicious." ( Figure 3 ).
case_images: Julius Friedrich Cohnheim (1839 - 1884), a German pathologist who published the case of " The image was taken from open source: . The first page of the article entitled "Einfacher Gallertkropf mit Metastasen" published in "Archiv fur pathologische Anatomie und Physiologie und fur klinische Medicin" in October 1876.
case_images: fendo-15-1354750-g004.jpg
case_images: PMC11096462_01_fendo-15-1354750-g004.jpg
case_images: f4
case_images: In October 1876, Julius Cohnheim, from Breslau, published a paper entitled "Simple Gelatinous Goiter with Metastasis." ( Figure 4 ).