case_images: PMC11098598_01
case_images: Mitochondrial chromosome DNA (ChrMT DNA) purification from the long-term ME/CFS female patient. 1. Extracellular ChrMT DNA isolated from the plasma; 2. cellular ChrMT DNA isolated from WBCs and platelets.
case_images: CRIG2024-6475425.002.jpg
case_images: PMC11098598_01_CRIG2024-6475425.002.jpg
case_images: fig2
case_images: The ChrMT DNA was isolated from the cells (including WBCs/platelets) and the plasma (Figure 2) and stored at -80 C before the sequencing analysis.
case_images: Methylamine tungstate, negatively stained, whole-mount TEM analysis of mitochondria (mt) isolated from the patient's plasma. Mitochondria with different shapes and sizes, ranging from ~400 nm (Panel (a)) to over 1 microm (Panel (f)), were identified. Some mitochondria are attached to "vesicle-like" structures protruding from the membrane (~100 nm in diameter), pointed by white arrows in Panels (a-c). Scale bar: 100 nm.
case_images: CRIG2024-6475425.003.jpg
case_images: PMC11098598_01_CRIG2024-6475425.003.jpg
case_images: fig3
case_images: Mitochondria were identified with altered shapes, including irregular shapes (Figure 3), and different sizes, ranging from 400 nm to over 1 mum. Some mitochondria appeared to "protrude" vesicle-like structures (approximately 100 nm in diameter) from the membrane (Figure 3).