case_images: PMC11165194_01
case_images: A chronological overview of the key events in the treatment journey of a 45-year-old male with muscle-invasive bladder cancer (A). PET/CT scans showed a 4.6 cm bladder base tumor extending into the bladder neck and prostatic urethra (B), with bilateral multiple pelvic lymph node involvement (C). The patient showed a complete response after 4 cycles of gemcitabine/cisplatin, with disappearance of the tumor (D); all pelvic lymph nodes subsided (E).
case_images: fonc-14-1397738-g001.jpg
case_images: PMC11165194_01_fonc-14-1397738-g001.jpg
case_images: f1
case_images: A 45-year-old Chinese male, married with one son, non-smoker, and non-drinker, and with no significant past medical history, initially presented in 2019 with non-muscle invasive BC (NMIBC) ( Figure 1A ). No evidence of distant metastasis was found ( Figures 1B, C ). Post-chemotherapy PET-CT scans revealed a complete response in the tumor and involved LNs ( Figures 1D, E ).
case_images: PMC11165194_02
case_images: A chronological overview of the key events in the treatment journey of a 57-year-old male with muscle-invasive bladder cancer (A). PET/CT scans showed a right posterior urinary bladder lesion medial to the ureteral orifice (B) with associated right hydronephrosis and involvement of multiple pelvic lymph nodes (C). The patient showed a good response after 4 cycles of gemcitabine/cisplatin, with complete remission in the bladder and pelvic lymph nodes (D, E), along with resolution of the hydronephrosis.
case_images: fonc-14-1397738-g002.jpg
case_images: PMC11165194_02_fonc-14-1397738-g002.jpg
case_images: f2
case_images: His initial management involved TURBT and intravesical BCG therapy ( Figure 2A ). Metastasis to multiple pelvic lymph nodes was noted but without distant metastasis ( Figures 2B, C ). A post-chemotherapy PET-CT scan showed complete remission in the bladder and pelvic LNs ( Figures 2D, E ).