case_images: PMC5612604_01
case_images: Histopathologic features of the urinary bladder tumor (a, b) and the cutaneous lesion (c, d).
case_images: CRIPA2017-4818537.001.jpg
case_images: PMC5612604_01_CRIPA2017-4818537.001.jpg
case_images: fig1
case_images: TURBT specimen, the presence of malignant tumor segments was ascertained, which were characterized by high cellular density areas. The cytological features of tumor cells included large nuclei with variation in size and prominent nucleoli (Figures 1(a) and 1(b)). III (Figures 1(c) and 1(d)). Immunohistochemical markers were positive for S100, Melan A, and HMB45 and negative for Cytokeratins and EMA.
case_images: Melan A immunopositivity in the cells of the TURBT specimen.
case_images: CRIPA2017-4818537.002.jpg
case_images: PMC5612604_01_CRIPA2017-4818537.002.jpg
case_images: fig2
case_images: Immunohistochemical expressions (Table 1) of S100 protein, Melan A (Figure 2), HMB45, and Vimentin were positive, while expressions of Cytokeratin AE1/AE3, Desmin, Chromogranin, and CD99 were negative.