case_images: PMC3134051_01
case_images: Gingival enlargement in the right upper anterior region between the lateral incisor and the canine
case_images: JISP-15-64-g001.jpg
case_images: PMC3134051_01_JISP-15-64-g001.jpg
case_images: F1
case_images: It was firm, lobulated, and attached to the gingiva by a narrow stalk [Figure 1].
case_images: Intraoral, periapical radiograph of the region showing no bony involvement
case_images: JISP-15-64-g002.jpg
case_images: PMC3134051_01_JISP-15-64-g002.jpg
case_images: F2
case_images: The radiological examination of the region showed no bony involvement [Figure 2].
case_images: Micrograph at low magnification showing plasma cell infiltrate and elongated rete ridges
case_images: JISP-15-64-g003.jpg
case_images: PMC3134051_01_JISP-15-64-g003.jpg
case_images: F3
case_images: Hemotoxylin and Eosin stain, revealed a stratified squamous parakeratinized hyperplastic epithelium, with underlying fibrocellular connective tissue stroma [Figure 3], with fibroblasts, few lymphocytes, and abundant plasma cells [Figure 4]. However, a typical eccentrically placed hyperchromatic, cartwheel-shaped nucleus of the plasma cell was also evident [Figure 5].
case_images: Low power microscopy showing abundant plasma cells in the connective tissue
case_images: JISP-15-64-g004.jpg
case_images: PMC3134051_01_JISP-15-64-g004.jpg
case_images: F4
case_images: Hemotoxylin and Eosin stain, revealed a stratified squamous parakeratinized hyperplastic epithelium, with underlying fibrocellular connective tissue stroma [Figure 3], with fibroblasts, few lymphocytes, and abundant plasma cells [Figure 4]. However, a typical eccentrically placed hyperchromatic, cartwheel-shaped nucleus of the plasma cell was also evident [Figure 5].
case_images: High power microscopy showing plasma cells with eccentrically placed nucleus
case_images: JISP-15-64-g005.jpg
case_images: PMC3134051_01_JISP-15-64-g005.jpg
case_images: F5
case_images: Hemotoxylin and Eosin stain, revealed a stratified squamous parakeratinized hyperplastic epithelium, with underlying fibrocellular connective tissue stroma [Figure 3], with fibroblasts, few lymphocytes, and abundant plasma cells [Figure 4]. However, a typical eccentrically placed hyperchromatic, cartwheel-shaped nucleus of the plasma cell was also evident [Figure 5].
case_images: Immunohistochemistry for kappa chains
case_images: JISP-15-64-g006.jpg
case_images: PMC3134051_01_JISP-15-64-g006.jpg
case_images: F6
case_images: A strong positivity for the kappa light chain was seen in the polyclonal plasma cell population [Figure 6], whereas, a weak expression was noted for the lambda light chain [Figure 7], with a ratio of 2:1.
case_images: Immunohistochemistry for lambda chains
case_images: JISP-15-64-g007.jpg
case_images: PMC3134051_01_JISP-15-64-g007.jpg
case_images: F7
case_images: A strong positivity for the kappa light chain was seen in the polyclonal plasma cell population [Figure 6], whereas, a weak expression was noted for the lambda light chain [Figure 7], with a ratio of 2:1.