case_images: PMC10767575_01
case_images: (a) EEG (21 years old): during drowsiness, bilateral, synchronous, and asynchronous spike-wave (SW) over the temporal-parietal regions enhanced by sleep, evolving to a pattern of continuous SW during sleep (SWAS). (b) Brain MRI (21 years old): diffuse, bilateral hyperintensity in T2-FLAIR of the subcortical white matter (retrotrigonal regions, semioval centers, pre and post-central gyrus) with reduced apparent diffusion coefficient (ADC), suggestive of diffuse hypomyelination. Posterior atrophy. The spectroscopy study was performed by placing two volumes on the right, in the altered white matter of the Rolandic region and in the morphologically apparently free over the frontal region. The results show a modest reduction in NAA/Cr and Cho/Cr ratios.
case_images: MGG3-12-e2311-g002.jpg
case_images: PMC10767575_01_MGG3-12-e2311-g002.jpg
case_images: mgg32311-fig-0001
case_images: The EEG still shows frequent epileptiform abnormalities during drowsiness that became continuous in sleep (Figure 1a).