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case_images: Ultrasonographic appearance of the jejunum (arrowhead) and ascending colon on a transverse section revealing increased wall thickness to 4.8 mm (arrow)
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case_images: Ultrasonography revealed moderately increased intestinal wall thickness (4.8 mm) from the ascending to proximal descending colon (Figure 1).
case_images: Endoscopic image of the transverse colon. Multiple haemorrhagic lesions are apparent in the friable mucous membrane
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case_images: Endoscopic examination revealed partial circumferential narrowing of the transverse colon and friable colonic mucosa with multiple haemorrhagic regions (Figure 2).
case_images: Colon. Lower magnification reveals thickening of the colonic wall. Marked ulceration of the colonic mucosa and distortion of the glandular architecture in the lamina propria are identified. Haematoxylin and eosin
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case_images: Histological examination with haematoxylin and eosin staining (HE) revealed marked ulceration of the colonic mucosa; marked alteration in the normal glandular architecture was observed in the lamina propria (Figure 3).
case_images: Colon. Marked transmural infiltration of foamy macrophages (arrow) is accompanied by neutrophils, plasma cells and lymphocytes
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case_images: The lesions consisted of marked transmural infiltration of foamy macrophages accompanied by neutrophils, plasma cells and lymphocytes (Figure 4).
case_images: Colon. Infiltration of periodic acid-Schiff stain-positive macrophages in the lamina propria
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case_images: The infiltrating macrophages were predominantly periodic acid-Schiff (PAS) positive (Figure 5).
case_images: Colon. Colonisation of bacilli is identified in the granulomatous lesion. Warthin-Starry stain
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case_images: Warthin-Starry, Ziehl-Neelsen and gram stains identified intracytoplasmic non-acid-fast, gram-negative bacilli in the macrophages on tissue section (Figure 6).
case_images: Colon. Numerous bacilli are identified in the colonic lamina propria. Immunohistochemistry for Escherichia coli lipopolysaccharide
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case_images: Iba-1+ macrophages and colonisation of E coli in the granulomatous lesions (Figure 7). In view of these findings, a final diagnosis of GC was made at day 21.