case_images: PMC4766327_01
case_images: Brain magnetic resonance imaging (horizontal) indicating a solid mass in the left temporal lobe.
case_images: CRIOG2016-9813253.001.jpg
case_images: PMC4766327_01_CRIOG2016-9813253.001.jpg
case_images: fig1
case_images: Brain magnetic resonance imaging (MRI) revealed a solid mass on the left temporal lobe (Figure 1).
case_images: Pedigree of the patient's family. The cancer type or site followed by the age of diagnosis is indicated for pancreatic carcinoma (Pancreatic ca) and breast cancer (Breast ca) and stomach cancer (Stomach ca). The age in years or weeks (wks) at the time of ascertainment or age at death (d.), if known, is shown.
case_images: CRIOG2016-9813253.002.jpg
case_images: PMC4766327_01_CRIOG2016-9813253.002.jpg
case_images: fig2
case_images: Her sisters and brother did not have cancer (Figure 2).
case_images: Histological examination indicates a diagnosis of invasive ductal carcinoma ((a) hematoxylin-eosin [HE] staining). Immunohistochemical examination indicates that the tumor was negative for human epidermal growth factor receptor 2 (HER-2) (b), estrogen receptor (ER) (c), and progesterone receptor (PR) (d). Moreover, the Ki-67 expression index is 80% (e).
case_images: CRIOG2016-9813253.003.jpg
case_images: PMC4766327_01_CRIOG2016-9813253.003.jpg
case_images: fig3
case_images: The Ki-67 expression index was 80% (Figure 3).
case_images: Positron emission tomography-computed tomography indicates the presence of lung metastasis at the left lung apex.
case_images: CRIOG2016-9813253.004.jpg
case_images: PMC4766327_01_CRIOG2016-9813253.004.jpg
case_images: fig4
case_images: To confirm whether there was metastasis at other locations, positron emission tomography-CT was also performed, and lung metastasis was detected (Figure 4).
case_images: Brain magnetic resonance imaging (horizontal) indicating the absence of the metastatic tumor after urgent craniotomy and chemoradiation.
case_images: CRIOG2016-9813253.005.jpg
case_images: PMC4766327_01_CRIOG2016-9813253.005.jpg
case_images: fig5
case_images: At present, she has not shown any signs of recurrence (Figure 5).