case_images: PMC9338354_01
case_images: Computed tomography defining the extent of the lesion.
case_images: DRJ-19-49-g001.jpg
case_images: PMC9338354_01_DRJ-19-49-g001.jpg
case_images: F1
case_images: A computer tomography revealed a well-defined horizontally oval homogenously enhancing lesion measuring 23 x 17 x 30 mm in Craniocaudal x Anteroposterior x Transverse dimensions noted in the right gingiva-buccal sulcus with broad base toward mandible extending from central incisors to second premolar [Figure 1].
case_images: Resection of the lesion in toto.
case_images: DRJ-19-49-g002.jpg
case_images: PMC9338354_01_DRJ-19-49-g002.jpg
case_images: F2
case_images: The lesion was carefully separated from the underlying the tissues, free margins identified, dissected, and removed in toto [Figure 2].
case_images: Histopathological examination of the excised specimen under x40.
case_images: DRJ-19-49-g003.jpg
case_images: PMC9338354_01_DRJ-19-49-g003.jpg
case_images: F3
case_images: Histopathological examination (HE) showed nodular tissue devoid of lining epithelium, composed of a tumor arranged in sheets and perivascular pattern [Figure 3].
case_images: Immunohistochemistry slides revealed the cells positive for CD99.
case_images: DRJ-19-49-g004.jpg
case_images: PMC9338354_01_DRJ-19-49-g004.jpg
case_images: F4
case_images: IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
case_images: Immunohistochemistry slides revealed the cells positive for spinal muscular atrophy.
case_images: DRJ-19-49-g005.jpg
case_images: PMC9338354_01_DRJ-19-49-g005.jpg
case_images: F5
case_images: IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
case_images: Immunohistochemistry slides revealed the cells positive for ERG.
case_images: DRJ-19-49-g006.jpg
case_images: PMC9338354_01_DRJ-19-49-g006.jpg
case_images: F6
case_images: IHC studies revealed the cells positive for CD99 [Figure 4], spinal muscular atrophy [Figure 5], ERG [Figure 6], and FLi (weak) while being negative for CK, CD45, CD34, CD31, HMB45, S100, DESMIN, WT1, and MyoD1.
case_images: Immunohistochemistry slides revealed the cells positive for Ki67.
case_images: DRJ-19-49-g007.jpg
case_images: PMC9338354_01_DRJ-19-49-g007.jpg
case_images: F7
case_images: Ki67 index was 20%, giving final diagnosis as malignant small round cell tumor favoring ES [Figure 7].