case_images: PMC10153454_01
case_images: Fine needle aspiration cytology (FNAC) for the diagnosis of CTVT. Plasmacytoid cytological subtypes (black arrow) and lymphocytoid (white arrow). Note the predominance of plasmacytoid oncocytes. Staining by Giemsa, at 63x objective.
case_images: bjvm-45-e000123-g01.jpg
case_images: PMC10153454_01_bjvm-45-e000123-g01.jpg
case_images: gf01
case_images: The tumor initially had adhered to the adjacent tissues, preventing exposure of the dog's penis, and leaving visible only its distal portion in preputial mucosa joined to the glans, which exhibited a friable hyperemic mass of cauliflower aspect (Figure 1).
case_images: Canine transmissible venereal tumor in a male dog. Multilobular vegetating mass, brittle and of reddish coloration adhering to the skin of the penis before the initiation of chemotherapy. Right ventrolateral view of the animal.
case_images: bjvm-45-e000123-g02.jpg
case_images: PMC10153454_01_bjvm-45-e000123-g02.jpg
case_images: gf02
case_images: Inflammatory infiltrate and mitotic figures were also observed (Figure 2).
case_images: Mass of a dog's penis after chemotherapeutic treatment. Note the redness on the abdominal skin (white arrow). Right ventrolateral view of the animal (A). Micrograph evidencing fibroblasts dispersed in extracellular matrix and collagenous fibers. Staining by H.E, at 20x objective (B).
case_images: bjvm-45-e000123-g03.jpg
case_images: PMC10153454_01_bjvm-45-e000123-g03.jpg
case_images: gf03
case_images: IV), weekly. Interestingly, after 6 sessions of chemotherapy, upon exposing the penis of the patient to evaluate the clinical evolution of the tumor, we observed the presence of a hardened vegetative multi-lobed mass with a smooth brilliant surface, and of pinkish-white coloration (Figure 3A). In which it was possible to observe a fibrotic process (Figure 3B), confirmed by Masson's trichrome staining (Figure 4).
case_images: Microscopy showing positive Masson's trichrome staining for collagen fibers in blue. Representing tissue fibrosis after chemotherapy with Vincristine. Staining by Masson's trichrome, at 20x objetive.
case_images: bjvm-45-e000123-g04.jpg
case_images: PMC10153454_01_bjvm-45-e000123-g04.jpg
case_images: gf04
case_images: In which it was possible to observe a fibrotic process (Figure 3B), confirmed by Masson's trichrome staining (Figure 4).