case_images: PMC5742511_01
case_images: A well-demarcated nodule is seen in the dermis (original magnification: x40).
case_images: CRIOT2017-8289710.001.jpg
case_images: PMC5742511_01_CRIOT2017-8289710.001.jpg
case_images: fig1
case_images: Microscopic examination showed a roundish, well-demarcated nodular tumor invading the mid- and deep-dermis, sparing the underlying ear cartilage (Figures 1 and 2).
case_images: The dermal tumor spares the underlying ear cartilage (original magnification: x40).
case_images: CRIOT2017-8289710.002.jpg
case_images: PMC5742511_01_CRIOT2017-8289710.002.jpg
case_images: fig2
case_images: Microscopic examination showed a roundish, well-demarcated nodular tumor invading the mid- and deep-dermis, sparing the underlying ear cartilage (Figures 1 and 2).
case_images: At higher magnification, the tumor consists of spindle cells with eosinophilic cytoplasm and blunt nuclei, forming fascicles surrounding the vessels with thick muscular walls (hematoxylin-eosin-saffron stain, original magnification: x250).
case_images: CRIOT2017-8289710.003.jpg
case_images: PMC5742511_01_CRIOT2017-8289710.003.jpg
case_images: fig3
case_images: Several vascular channels were seen within the nodule, and at the periphery of the lesion, several small round vessels with a thick smooth-muscle wall were present, often merging with the main spindle-cell population of the nodule (Figure 3).
case_images: By immunohistochemistry, tumor cells express caldesmon (immunoperoxidase revealed with aminoethylcarbazole) (original magnification: x250).
case_images: CRIOT2017-8289710.004.jpg
case_images: PMC5742511_01_CRIOT2017-8289710.004.jpg
case_images: fig4
case_images: The immunohistochemical study showed that the tumor cells expressed smooth-muscle markers, that is, caldesmon (Figure 4), desmin, and smooth-muscle actin, but not keratin.