case_images: PMC6201621_01
case_images: PMC6201621_02
case_images: Radiological findings: A) bladder ultrasonography T: tumor; F: Foley catheter; B) non-contrast-computed tomography image, lymph node swelling (asterisks); C) JJ stent after transurethral resection
case_images: PAMJ-30-134-g001.jpg
case_images: PMC6201621_02_PAMJ-30-134-g001.jpg
case_images: f0001
case_images: Mild dilatation was observed in the left kidney and an approximately four cm mass in the left lateral wall of the bladder were observed at CT (Figure 1).
case_images: Histological examination: tumoral tissue with intense cellularity in a loose vascularized stroma, hematoxylin-eosin staining, x200; B) diffuse areas of necrosis and hemorrhage in the tumor, x100; C) synaptofizin positive, x400; D) chromogranin A positive, x200; E) CD56 positive, x400; F) CD44 negative, x400)
case_images: PAMJ-30-134-g002.jpg
case_images: PMC6201621_02_PAMJ-30-134-g002.jpg
case_images: f0002
case_images: Immunohistochemically, the tumor neuroendocrine tumor differentiation markers CD56, chromogranin A and synaptophysin were positive while CD44 was negative, exhibiting neuroendocrine differentiation (Figure 2, Figure 3).
case_images: Large numbers of atypical mitotic figures in all fields (indicated by an arrow), hematoxylin-eosin staining, x400
case_images: PAMJ-30-134-g003.jpg
case_images: PMC6201621_02_PAMJ-30-134-g003.jpg
case_images: f0003
case_images: Immunohistochemically, the tumor neuroendocrine tumor differentiation markers CD56, chromogranin A and synaptophysin were positive while CD44 was negative, exhibiting neuroendocrine differentiation (Figure 2, Figure 3).