case_images: PMC9218342_01
case_images: PMC9218342_02
case_images: Comparison of images on US (A, B) and CT (C, D) of the patient before and after 8 months. Eight months later, the lesion was much larger with unclear boundaries, and there were much more calcifications.
case_images: fonc-12-875793-g001.jpg
case_images: PMC9218342_02_fonc-12-875793-g001.jpg
case_images: f1
case_images: A calcified mass was found at the first examination of ultrasonography (US) and computed tomography (CT) plain scan and contrast enhancement of chest (Figure 1). BI-RADS category 4C because of its rapid growth and more calcifications at the examination of US and CT plain scan and contrast enhancement of chest (Figure 1). Biopsy was performed according to the patient's preference, resulting in specimens showing to be a malignant phyllodes tumor of the breast with ossification or osteosarcoma.
case_images: The 99mTc-MDP whole-body bone imaging. It showed that there was a mass-like abnormal radioactive concentration of Tc-99m outside the bone of the left chest, without other abnormal concentrations.
case_images: fonc-12-875793-g002.jpg
case_images: PMC9218342_02_fonc-12-875793-g002.jpg
case_images: f2
case_images: Then, 99mTc-MDP whole-body bone imaging was performed, and it showed that there was a mass-like abnormal radioactive concentration of Tc-99m outside the bone of the left chest, without other abnormal concentrations (Figure 2).
case_images: The gross specimen (A) and the histologic result (B:ross specimen (A) showed a 7 cm x 8 cm x 8 cm mass in the central region with clear boundary, regular shape, and pectoralis major invaded, and the histologic result (B: HEx40) showed that it was rich in osteoid tissues, heteromorphic osteoblast-like cells, and multinucleated giant cells.
case_images: fonc-12-875793-g003.jpg
case_images: PMC9218342_02_fonc-12-875793-g003.jpg
case_images: f3
case_images: Mastectomy and axillary lymph node dissection was performed on the left breast, and the histological results were observed (Figure 3).
case_images: Timeline.
case_images: fonc-12-875793-g004.jpg
case_images: PMC9218342_02_fonc-12-875793-g004.jpg
case_images: f4
case_images: Four months later, she died of respiratory failure caused by multiple lung metastases (Figure 4).