case_images: PMC5366790_01
case_images: Lateral anterior border of the tongue showing a large ulcerated lesion with indurated borders.
case_images: CRIM2017-1489501.001.jpg
case_images: PMC5366790_01_CRIM2017-1489501.001.jpg
case_images: fig1
case_images: According to the patient the lesion has been growing for the last 5 months (Figure 1).
case_images: Excisional biopsy of the lesion.
case_images: CRIM2017-1489501.002.jpg
case_images: PMC5366790_01_CRIM2017-1489501.002.jpg
case_images: fig2
case_images: After an excisional biopsy the diagnosis was of coccidioidomycosis (Figure 2).
case_images: Chronic granulomatous inflammatory infiltrate, showing lymphocytes, plasma cells, and multinucleated giant cells containing spherical cytoplasmic inclusions corresponding to Coccidioides immitis (H&E; 200x).
case_images: CRIM2017-1489501.003.jpg
case_images: PMC5366790_01_CRIM2017-1489501.003.jpg
case_images: fig3
case_images: C. PAS staining highlighting various bodies of C. immitis in red color (PAS).
case_images: CRIM2017-1489501.004.jpg
case_images: PMC5366790_01_CRIM2017-1489501.004.jpg
case_images: fig4
case_images: C. Grocott staining confirming the presence of large bodies of C. immitis in black (Grocott).
case_images: CRIM2017-1489501.005.jpg
case_images: PMC5366790_01_CRIM2017-1489501.005.jpg
case_images: fig5
case_images: Immunohistochemistry showing granulomatous inflammation with predominance of macrophages and giant multinucleated cells positive for CD68, containing bodies of C. immitis (200x).
case_images: CRIM2017-1489501.006.jpg
case_images: PMC5366790_01_CRIM2017-1489501.006.jpg
case_images: fig6