case_images: PMC7568163_01
case_images: Our patient's initial chest CT scan showing scattered ground glass opacities bilaterally (red circle).
case_images: CRIONM2020-8048056.001.jpg
case_images: PMC7568163_01_CRIONM2020-8048056.001.jpg
case_images: fig1
case_images: Computerized tomography (CT) of the chest revealed scattered ground glass opacities bilaterally (Figure 1).
case_images: Follow-up chest CT scan showing an 8 mm left lower lobe pulmonary nodule (red arrow) which appeared to be enlarging.
case_images: CRIONM2020-8048056.002.jpg
case_images: PMC7568163_01_CRIONM2020-8048056.002.jpg
case_images: fig2
case_images: On her latest CT scan of the chest, there was an 8 mm left lower lobe pulmonary nodule which appeared to be enlarging (Figure 2).
case_images: Hematoxylin and eosin stain of transthoracic needle lung biopsy. This slide is at 40x magnification. The sections show multiple cores of lung parenchyma, some of which contain an intra-alveolar infiltrate of relatively monomorphic tumor cells with round nuclei and a moderate eosinophilic cytoplasm. The cells are set in a myxohyaline stroma. Scattered areas show intracytoplasmic lumina, and there are also intranuclear inclusions. Most of the tumor appears to be intra-alveolar and the surrounding lung parenchyma shows mildly prominent type II pneumocytes. There is no evidence of significant nuclear atypia, mitoses, or necrosis.
case_images: CRIONM2020-8048056.003.jpg
case_images: PMC7568163_01_CRIONM2020-8048056.003.jpg
case_images: fig3
case_images: TTF-1, Pax-8, CAM 5.2, EMA, CDX2, CK20, and CK7 were negative in the tumor cells. The findings fit with a low-grade epithelioid hemangioendothelioma (Figures 3, 4, and 5).
case_images: Immunohistochemical stain showing uptake of CD31.
case_images: CRIONM2020-8048056.004.jpg
case_images: PMC7568163_01_CRIONM2020-8048056.004.jpg
case_images: fig4
case_images: TTF-1, Pax-8, CAM 5.2, EMA, CDX2, CK20, and CK7 were negative in the tumor cells. The findings fit with a low-grade epithelioid hemangioendothelioma (Figures 3, 4, and 5).
case_images: Immunohistochemical stain showing uptake of ERG.
case_images: CRIONM2020-8048056.005.jpg
case_images: PMC7568163_01_CRIONM2020-8048056.005.jpg
case_images: fig5
case_images: TTF-1, Pax-8, CAM 5.2, EMA, CDX2, CK20, and CK7 were negative in the tumor cells. The findings fit with a low-grade epithelioid hemangioendothelioma (Figures 3, 4, and 5).