case_images: PMC5137636_01
case_images: Preoperative photograph showing right breast mass and incision lines for planned conservative breast approach
case_images: 003588414x13824511649210-1.jpg
case_images: PMC5137636_01_003588414x13824511649210-1.jpg
case_images: fig1
case_images: A 35-year-old woman presented to the surgical outpatient clinic of the National Cancer Institute at Cairo University with a rapidly growing right breast mass (Fig 1). Incision was planned preoperatively with an inferior-based breast reduction plan (Fig 1).
case_images: Gross specimen following excision
case_images: 003588414x13824511649210-2.jpg
case_images: PMC5137636_01_003588414x13824511649210-2.jpg
case_images: fig2
case_images: Complete excision of the mass was carried out with negative safety margins (Fig 2) confirmed by intraoperative frozen section.
case_images: Follow-up photograph one month after conservative breast surgery. There was no need for contralateral reduction mammoplasty. (No major discrepancy in breast symmetry.)
case_images: 003588414x13824511649210-3.jpg
case_images: PMC5137636_01_003588414x13824511649210-3.jpg
case_images: fig3
case_images: Local glandular flaps were used to reconstruct the remaining breast volume (Fig 3) without major discrepancy in breast symmetry.
case_images: Gross specimen: tumour measured 19cm x 9cm x 9cm; lobulated, firm, friable, whitish mass with few chondroid and wide myxoid areas with focal cystic change and haemorrhagic foci
case_images: 003588414x13824511649210-4.jpg
case_images: PMC5137636_01_003588414x13824511649210-4.jpg
case_images: fig4
case_images: Gross and microscopic pictures of the excised mass (Figs 4-6) were consistent with the picture of rare extraskeletal chondrosarcoma, myxoid type.
case_images: Microscopic picture showing nodules separated by fibrous septa and populated by cellular groups of malignant small to medium-sized round cells lying in lacunar spaces and having vesicular nuclei and prominent nucleoli, disposed in a loose myxoid, focally chondrohyaline matrix. (Few tumour nodules showed peripheral rim of calcific shell. No epithelial component could be detected and the possibility of a malignant phyllodes tumour, a carcinosarcoma or a metaplastic carcinoma was therefore excluded.)
case_images: 003588414x13824511649210-5.jpg
case_images: PMC5137636_01_003588414x13824511649210-5.jpg
case_images: fig5
case_images: Gross and microscopic pictures of the excised mass (Figs 4-6) were consistent with the picture of rare extraskeletal chondrosarcoma, myxoid type.
case_images: Immunohistochemistry showing a positive reaction of the tumour cells to S100 protein, and a negative reaction to casein kinase, calponin and actin
case_images: 003588414x13824511649210-6.jpg
case_images: PMC5137636_01_003588414x13824511649210-6.jpg
case_images: fig6
case_images: Gross and microscopic pictures of the excised mass (Figs 4-6) were consistent with the picture of rare extraskeletal chondrosarcoma, myxoid type.