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case_images: Preoperative imaging images. (A) Ultrasound examination detected the left thyroid gland measuring approximately 9 cm. (B) Ultrasound examination detected the right thyroid gland measuring over 6 cm. (C) The isthmus of the thyroid displayed a thickness of 1.6 cm. (D) Computed tomography imaging demonstrates significant enlargement of the thyroid gland, resulting in evident compression and displacement of the trachea.
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case_images: Furthermore, the isthmus of the thyroid displayed a thickness of 1.6 cm ( Figures 1A-C ). Furthermore, the computed tomography (CT) scan demonstrated significant enlargement of the thyroid gland, resulting in evident compression and displacement of the trachea ( Figure 1D ).
case_images: (A, B) Histopathological examination (HE) staining of MALT lymphoma. The presence of lymphoproliferative lesions on thyroid glands, atrophy of thyroid follicles, active hyperplasia of a small number of follicular epitheliums. (C) Immunohistochemistry (IHC) analysis demonstrated positive expression of CD20. (D) Histopathological examination (HE) staining of PTC, there is a typical cancer nest change in the thyroid gland.
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case_images: Subsequent intraoperative histopathological examination confirmed the presence of lymphoproliferative lesions on both thyroid glands, atrophy of thyroid follicles, active hyperplasia of a small number of follicular epitheliums ( Figures 2A, B ), and the presence of a 0.5 cm papillary thyroid carcinoma on the right thyroid gland based on the pathological findings ( Figure 2D ). Additionally, there was no evidence of diffuse large B-cell lymphoma (DLBCL) since the B-cell size was either normal or slightly enlarged ( Figures 2A, B ).