case_images: PMC11741629_01
case_images: CASE augmentation process with a study period P = 20 years.
case_images: pone.0315928.g002.jpg
case_images: PMC11741629_01_pone.0315928.g002.jpg
case_images: pone.0315928.g002
case_images: For example, if a currently survived patient (deltai = 0) had a transplant six years ago and we are interested in P = 20 years of survival, the censoring time is ti = 6, and the patient's record will be replicated six times,  tau   {1, ...6}, with positive records yitau = 1, and no replications with yitau = 0 (Fig 2, sample ID 7). Conversely, if that patient died (deltai = 1) ti = 6 years after transplant (Fig 2, sample ID 8), the record is replicated 20 times with positive records yitau = 1 for the first six replications,  tau   {1, ..., 6}, and negative records (yitau = 0) for the remaining 14 replications,  tau   {7, ..., 20}. In Fig 2, the sample size of  is n = 149 with a positive class ratio of 43%, compared to an original sample size of 10 for a survival study, or a sample size of six with a class ratio of 17% for a 20-year binary classification study.
case_images: Survival curves for five randomly selected patients with actual time marked.. Note that KM produces only a single population curve. A: actual graft survival; P: predicted graft survival.
case_images: pone.0315928.g007.jpg
case_images: PMC11741629_01_pone.0315928.g007.jpg
case_images: pone.0315928.g007
case_images: For example, if a currently survived patient (deltai = 0) had a transplant six years ago and we are interested in P = 20 years of survival, the censoring time is ti = 6, and the patient's record will be replicated six times,  tau   {1, ...6}, with positive records yitau = 1, and no replications with yitau = 0 (Fig 2, sample ID 7).
case_images: Distribution of predicted survival probabilities at the time of event.
case_images: pone.0315928.g008.jpg
case_images: PMC11741629_01_pone.0315928.g008.jpg
case_images: pone.0315928.g008
case_images: Conversely, if that patient died (deltai = 1) ti = 6 years after transplant (Fig 2, sample ID 8), the record is replicated 20 times with positive records yitau = 1 for the first six replications,  tau   {1, ..., 6}, and negative records (yitau = 0) for the remaining 14 replications,  tau   {7, ..., 20}.
case_images: PMC11741629_02
case_images: Distribution of observed survival times in the liver transplant SRTR dataset.
case_images: pone.0315928.g005.jpg
case_images: PMC11741629_02_pone.0315928.g005.jpg
case_images: pone.0315928.g005
case_images: The survival distribution of the final dataset is shown in Fig 5.