case_images: PMC10691445_01
case_images: A - gross view of the lesion over the left ear's cavum concha; B - head computed tomography, axial view showing a homogeneous, well-circumscribed, round lesion over the lateral aspect of the left external auditory canal and adjacent to cavum concha (arrowhead).
case_images: autopsy-13-e2023447-g02.jpg
case_images: PMC10691445_01_autopsy-13-e2023447-g02.jpg
case_images: gf02
case_images: The lesion was 10 x 8 mm, firm, non-tender, and gradually progressed to the present size (Figure 2A). The lesion did not seem to infiltrate the underlying cartilage or erode the overlying skin (Figure 2B).
case_images: Photomicrographs of the tumor. A - compact nests of basaloid cells arranged together resembling a jigsaw puzzle pattern (H&E; 100X); B - nests are composed of an outer layer of peripheral palisading cells with small, dark nuclei and centrally located ductal cells with larger, pale nuclei. These nests are surrounded by a thickened, hyalinized membrane (H&E; 400X).
case_images: autopsy-13-e2023447-g03.jpg
case_images: PMC10691445_01_autopsy-13-e2023447-g03.jpg
case_images: gf03
case_images: Focal luminal differentiation was seen (Figure 3).
case_images: Photomicrographs of the tumor. Immunohistochemistry. A - central cells are immuno-positive for CK7; B - central cells are immuno-reactive for CK8 /18; C - luminal areas showing EMA immuno-reactivity; D - luminal areas showing CEA immuno-positivity.
case_images: autopsy-13-e2023447-g04.jpg
case_images: PMC10691445_01_autopsy-13-e2023447-g04.jpg
case_images: gf04
case_images: The central basaloid cells were immuno-reactive for CK7 and CK8/18, with luminal differentiation areas exhibiting immunopositivity for CEA and EMA (Figure 4).