case_images: PMC11003583_01
case_images: Light microscopy photo-micrograph showing glomerulus with mesangiolysis, intra-capillary fibrin thrombi, and the presence of fragmented RBCs in glomerular capillary lumina and mesangial areas (thrombotic micro-angiopathy) (Masson's TrichromeX200).
case_images: IJN-34-074-g001.jpg
case_images: PMC11003583_01_IJN-34-074-g001.jpg
case_images: F1
case_images: Occasional arterioles showed necrotizing lesions with the presence of fragmented RBC and luminal thrombotic occlusion, suggestive of TMA [Figure 1].
case_images: (a) Electron microscopy image showing loss of glomerular endothelial fenestrations and a marked expansion of the subendothelial area indicative of severe endothelial injury (EM X 2500) (b) Electron microscopy image showing paramesangial electron-dense deposits (EM X4000).
case_images: IJN-34-074-g002.jpg
case_images: PMC11003583_01_IJN-34-074-g002.jpg
case_images: F2
case_images: Electron microscopy [Figure 2] revealed loss of glomerular endothelial fenestrations and marked expansion of the subendothelial area and paramesangial electron-dense deposits, indicative of severe endothelial injury.
case_images: (a and b) MRI revealed multiple T2/FLAIR hyper-intensities of variable sizes in bilateral cerebral hemispheres, predominantly in the bilateral ganglio-capsular region (left > right) and bilateral occipital lobes, with minimal mass effect evident in the form of chinking of bilateral lateral ventricles adjacent to the lesions. (c and d) MRI revealed complete resolution of T2/FLAIR hyper-intensities in bilateral occipital regions and the left ganglio-capsular region with complete resolution of the mass effect. There was minimal residual hyper-intensity in the right ganglio-capsular region.
case_images: IJN-34-074-g003.jpg
case_images: PMC11003583_01_IJN-34-074-g003.jpg
case_images: F3