case_images: PMC10822910_01
case_images: (A) OCT image of the patient with the paracentral scotoma with oral 3-day oseltamivir, showing the macular edema (red arrowhead) and the hyperreflectivity at the retinal outer layer (yellow arrowhead). (B) the AMN lesions in the outer retinal layer can be found easily (yellow arrowhead) with 1 week of oral oseltamivir. (C) some repair of the microcapsule cavity (red arrowhead) in the retina and the structure of the outer retinal layer 2 weeks of treatment (yellow arrowhead). (D) the retinal structure was obviously repaired at the 1-month follow-up appointment (yellow arrowhead).
case_images: fimmu-14-1302504-g001.jpg
case_images: PMC10822910_01_fimmu-14-1302504-g001.jpg
case_images: f1
case_images: Omicron strains. Optical coherence tomography (OCT) conducted at a local hospital revealed macular edema (ME) in both eyes ( Figure 1A ). A 1-month follow-up showed the presence of a microcapsule cavity in the retina of both eyes ( Figure 1C ) and significant repair of the retinal structure ( Figure 1D ).
case_images: (A) the wedge-like AMN lesion is classic (yellow arrowhead) and some perivascular cotton plaques (blue arrowhead) in the fundus photograph. (B) IR image showing a wedge-like AMN lesion (yellow arrowhead) and radial weak reflex lesions (blue arrowhead). (C) the SD-OCT image shows the hyperreflectivity at the retinal outer layer (yellow arrowhead) with PAMM lesion in inner retinal layers (orange arrowhead). (D) the AMN lesion is an unremarkable weak reflex lesion (yellow arrowhead), and there is a perivascular weak reflex lesion not detectable (blue arrowhead) in the AF image. (E, F) FFA showed the unremarkable weak reflex lesions (yellow arrowhead) and the perivascular occluded fluorescence (blue arrowhead) at the early stage, then the weak reflex lesion in macula (yellow arrowhead), and the strong perivascular fluorescence at the later stage (blue arrowhead). (G) the OCTA image showed the decreased density of SCP and DCP.
case_images: fimmu-14-1302504-g002.jpg
case_images: PMC10822910_01_fimmu-14-1302504-g002.jpg
case_images: f2
case_images: Classic wedge-like lesions were detected in infrared reflectance (IR) and fundus photography at our hospital ( Figures 2A, B ), but weak reflex lesions were unremarkable in Autofluorescence (AF) ( Figure 2D ). Figure 2C ). Further examinations using fundus fluorescein angiography (FFA) and optical coherence tomography angiography (OCTA) were conducted. FFA results showed preretinal arteriolar obstruction in both eyes, with perivascular fluorescence shielded in the early angiography, and perivascular fluorescence leakage and mild telangiectasia in the later stage, corresponding to the lesions in the IR image ( Figures 2E, F ). OCTA revealed an incomplete macular arch ring structure and hypoperfusion in both the superficial capillary plexus (SCP) and the deep capillary plexus (DCP) ( Figure 2G ).