case_images: PMC3891405_01
case_images: Skin lesions of case I. There are numerous, small subcutaneous nodules of neurofibroma and brownish-pigmented lesions (cafe au lait spots) in the trunk.
case_images: kjim-20-100-g001.jpg
case_images: PMC3891405_01_kjim-20-100-g001.jpg
case_images: F1
case_images: A physical examination revealed a large, hard soft-tissue mass bulging out from the middle abdomen, and numerous, small subcutaneous neurofibroma nodules and brownish-pigmented lesions (cafe au lait spots) in the trunk and extremities (Figure 1). An abdominal CT scan demonstrated a large (approximately 9x10 cm) inhomogeneous mass with an area of central necrosis (Figure 2).
case_images: Abdominal CT scan of case I demonstrating a large (approximately 9x10 cm) inhomogeneous mass with an area of central necrosis.
case_images: kjim-20-100-g002.jpg
case_images: PMC3891405_01_kjim-20-100-g002.jpg
case_images: F2
case_images: A physical examination revealed a large, hard soft-tissue mass bulging out from the middle abdomen, and numerous, small subcutaneous neurofibroma nodules and brownish-pigmented lesions (cafe au lait spots) in the trunk and extremities (Figure 1). An abdominal CT scan demonstrated a large (approximately 9x10 cm) inhomogeneous mass with an area of central necrosis (Figure 2).
case_images: (A) The tumor cells show frequent mitoses of more than five per one high power field (H & E stain, x400). (B) Immunohistochemical stain for the S-100 protein shows a positive reaction.
case_images: kjim-20-100-g003.jpg
case_images: PMC3891405_01_kjim-20-100-g003.jpg
case_images: F3
case_images: The histopathology of the circumscribed and encapsulated mass obtained by a wide excision indicated a MPNST from the mesentery showing frequent mitoses in more than five per one high power field (Figure 3A). In the immunohistochemical stain, the tumor cells stained positively to the S-100 protein, which is a cytoplasmic marker used for identifying Schwann cells (Figure 3B).
case_images: PMC3891405_02
case_images: Chest PA (A) and CT scan (B) of case II show a homogenous mass measuring 3.5 cmx2.5 cm at the left upper lung field with a well-demarcated margin.
case_images: kjim-20-100-g004.jpg
case_images: PMC3891405_02_kjim-20-100-g004.jpg
case_images: F4
case_images: A chest PA and CT scan demonstrated a homogenous mass measuring 3.5x2.5 cm at the left upper lung field with a well-demarcated margin (Figure 4A, 4B). A wide excision was performed.
case_images: Chest CT scan of case II shows an inhomogeneous mass and a large amount of a left pleural effusion.
case_images: kjim-20-100-g005.jpg
case_images: PMC3891405_02_kjim-20-100-g005.jpg
case_images: F5
case_images: A chest CT scan demonstrated an inhomogeneous mass and a large amount of a left pleural effusion (Figure 5).
case_images: The chest CT scan shows that the tumor is markedly reduced after chemotherapy.
case_images: kjim-20-100-g006.jpg
case_images: PMC3891405_02_kjim-20-100-g006.jpg
case_images: F6
case_images: After 6 cycles of MAID combination chemotherapy, a CT scan showed that the mass was markedly reduced (Figure 6).