case_images: PMC8655352_01
case_images: Apical 4 chamber during fetal echocardiography at 32 weeks of gestation. Cardiac ventricular asymmetry and right ventricle cardiac hypertrophy. LV: Left Ventricle; RV: Right Ventricle; RVH: Right Ventricle Hypertrophy.
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case_images: PMC8655352_01_fphar-12-756056-g001.jpg
case_images: F1
case_images: The third revealed cardiac ventricular asymmetry and a right ventricle cardiac hypertrophy (Figure 1).
case_images: Supra-systemic pulmonary hypertension was assessed on echocardiography. Parasternal short axis ventricles (A): Bowing of the interventricular septum into the left ventricle. Apical 4 chamber (B): Tricuspid regurgitation blood flow velocities higher than 4 m.s-1. RV: Right Ventricle; LV: Left Ventricle; IVS: Interventricular Septum.
case_images: fphar-12-756056-g002.jpg
case_images: PMC8655352_01_fphar-12-756056-g002.jpg
case_images: F2
case_images: The newborn was admitted to the Neonatal Intensive Care Unit where an echocardiography showed supra-systemic pulmonary hypertension with tricuspid regurgitation blood flow velocities of 60 mmHg (Figure 2), whereas systolic blood pressure was 54 mmHg.
case_images: Change of pulmonary artery systolic pressures (mmHg) estimated by measuring peak systolic tricuspid regurgitation velocity. PAPs normalized 2 months after birth. D, Day.
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case_images: PMC8655352_01_fphar-12-756056-g003.jpg
case_images: F3
case_images: Symptoms improved on day 17, the ductus arteriosus was closed at day 20 and the infant was discharged from hospital on day 24 with normalization of pulmonary pressures (Figure 3). Sildenafil was stopped on day 157.