case_images: PMC10868795_01
case_images: 63-year-old caucasian patient with intense slate-gray pigmentation.
case_images: dp1401a8g001.jpg
case_images: PMC10868795_01_dp1401a8g001.jpg
case_images: f1-dp1401a8
case_images: (A) The epidermis shows solar lentigo-like characteristics while melanophages containing cytoplasmic melanin are visible in the dermis. (B) Perivascular and peri-adnexal distribution of macrophages. (C) High expression of CD68 pgm-1 by superficial dermal melanophages. (D) Negative immunohistochemical study for SOX-10 (D).
case_images: dp1401a8g002.jpg
case_images: PMC10868795_01_dp1401a8g002.jpg
case_images: f2-dp1401a8
case_images: Immunohistochemistry was negative for pS100, Sox10, HMB45; positive for CD68 pgm1, supporting the diagnosis of diffused cutaneous melanosis (Figure 2).