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case_images: T2-weighted FLAIR MR Images obtained by magnetic resonance imaging (MRI) scans. (A,B) The matched control's brain MR images show the normal lateral ventricles (A) and mild atrophy without septum pellucidum cyst (SPC) (B). (C,D) The patient's brain MR images show the enlarged double lateral ventricles (C) and the SPC between the lateral ventricles (arrow) (D). And the walls of the cyst are laterally bowed, which compress the lateral ventricles (D). After removing the SPC (E,F), the patient's brain MR images show lessened enlargement of the lateral ventricles (arrows) (E) and the disappeared SPC in the middle line area (arrows) (F).
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case_images: PMC5604059_01_fnagi-09-00299-g0001.jpg
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case_images: Table 1), therefore we gave a diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA Criteria 2011. Moreover, compared with the matched control whose brain shows mild atrophy without SPC, and his cognitive functions are normal (Figures 1A,B). The MRI results showed that the double lateral ventricles were significantly expanded (Figure 1C) and the space-occupying lesions in the midline area were clearly observed (Figure 1D). MRI results confirmed a shrinkage of the expanded lateral ventricles (Figure 1E) and elimination of SPC (Figure 1F). Meanwhile, his MMSE score was 28 (see Table 1), and he was able to be competent at both his job and daily life.