case_images: PMC3424652_01
case_images: Gross examination reveal pink-tan tissue fragments.
case_images: CRIM.GM2012-141693.001.jpg
case_images: PMC3424652_01_CRIM.GM2012-141693.001.jpg
case_images: fig1
case_images: Gross examination revealed two portions of pink-tan tissue measuring 7.3 x 2.8 x 1.4 cm and 4.5 x 2.8 x 1.2 cm (Figure 1).
case_images: Area of well-differentiated fatty component (arrow). The lesion is submucosal.
case_images: CRIM.GM2012-141693.002.jpg
case_images: PMC3424652_01_CRIM.GM2012-141693.002.jpg
case_images: fig2
case_images: Microscopic examination revealed a biphasic submucosal neoplasm (Figure 2) composed of a well-differentiated lipomatous component adjacent to a high-grade spindle cell sarcoma.
case_images: Examination of the fibrous septa shows atypical hyperchromatic stromal cells (arrow) and scattered lipoblasts (arrowhead).
case_images: CRIM.GM2012-141693.003.jpg
case_images: PMC3424652_01_CRIM.GM2012-141693.003.jpg
case_images: fig3
case_images: Examination of the well-differentiated areas showed mature adipose tissue with fibrous septae containing atypical hyperchromatic stromal cells and scattered lipoblasts (Figure 3) which involved the surgical resection margin.
case_images: The high-grade component was composed of atypical spindle cells with nuclear hyperchromasia.
case_images: CRIM.GM2012-141693.004.jpg
case_images: PMC3424652_01_CRIM.GM2012-141693.004.jpg
case_images: fig4
case_images: The morphologically high-grade component corresponded to the firm area identified grossly and was composed of atypical spindle cells with nuclear hyperchromasia and easily identifiable mitotic figures (Figure 4).
case_images: Fluorescence in situ hybridization studies showed amplification of the CPM gene.
case_images: CRIM.GM2012-141693.005.jpg
case_images: PMC3424652_01_CRIM.GM2012-141693.005.jpg
case_images: fig5
case_images: Fluorescence in situ hybridization studies showed amplification of the CPM gene (Figure 5).