case_images: PMC10837784_01
case_images: Sigmoidoscopy images showing normal-looking mucosa.. Descending colon (A), Sigmoid colon (B), Rectum (C)
case_images: cureus-0016-00000051638-i01.jpg
case_images: PMC10837784_01_cureus-0016-00000051638-i01.jpg
case_images: FIG1
case_images: The examination was done till the descending colon (Figure 1A). Biopsies were obtained from both the descending and sigmoid colon (Figure 1B).
case_images: Histological appearance of collagenous colitis.. (A) and (B) (H&E, 20X and 4X, respectively) show colonic mucosa with intact crypt architecture and no significant inflammation. (A) exhibits colonic mucosa with a thickened subepithelial collagen band (arrow) with entrapped inflammatory cells. (C) shows Masson trichrome special stain highlighting a thick collagen band (arrow) under the surface epithelium, consistent with collagenous colitis.
case_images: cureus-0016-00000051638-i02.jpg
case_images: PMC10837784_01_cureus-0016-00000051638-i02.jpg
case_images: FIG2
case_images: The histopathology report yielded a thickened subepithelial collagen band with entrapped inflammatory cells (Figures 2A-2C).