case_images: PMC10898597_01
case_images: Mucous membrane pemphigoid with the oral predominant response to abrocitinib therapy. (a) before the abrocitinib therapy. (b) Two weeks later after the abrocitinib therapy. (c) Four weeks later after the abrocitinib therapy.
case_images: PPA-18-503-g0001.jpg
case_images: PMC10898597_01_PPA-18-503-g0001.jpg
case_images: f0001
case_images: Physical examination revealed that post-blistering erosions were mainly present on the left palatal mucosa (Figure 1a) and several small fluid-filled blisters and erythema were scattered on the scalp, trunk, and limbs. Two weeks later, the oral erosions had mostly subsided (Figure 1b); 4 weeks later, they had disappeared without any accompanying pain and discomfort (Figure 1c), and the skin blisters were mostly dry.
case_images: (a) A cleavage between the epidermis and dermis with a few infiltrations of eosinophils and lymphocytes. (b) Direct immunofluorescence showed IgG was deposited linearly in the basement membrane zone.
case_images: PPA-18-503-g0002.jpg
case_images: PMC10898597_01_PPA-18-503-g0002.jpg
case_images: f0002
case_images: Histopathology of a blister on the scalp revealed that there was a cleavage between the epidermis and dermis with a few eosinophils and lymphocyte infiltrations (Figure 2a). Direct immunofluorescence testing found linear immunoglobulin G (IgG) and C3 deposits along the dermoepidermal junction (Figure 2b).