case_images: PMC10248421_01
case_images: Cranial MRI in Case 1. Axial T2 weighted (A) and FLAIR (B) sequences showed hyper-intensity in the right hippocampus. 20 months after immunotherapy, a control cranial MRI showed a significant reduction of right hippocampus hyper-intensity in T2 (C) weighted and FLAIR (D) sequences. 28 months after immunotherapy, no significant changes contrasted (E, F) with (C, D).
case_images: fimmu-14-1191823-g001.jpg
case_images: PMC10248421_01_fimmu-14-1191823-g001.jpg
case_images: f1
case_images: A cranial MRI showed hyper-intensity in the right hippocampus on T2 and fluid attenuated inversion recovery (FLAIR) sequences ( Figure 1 ). However, a follow-up cranial MRI showed a significant reduction of right hippocampus hyper-intensity on T2 weighted and FLAIR sequences ( Figure 1 ).
case_images: PMC10248421_02
case_images: PMC10248421_03
case_images: Cranial MRI in Case 3. Axial T2 weighted (A) and FLAIR (B) sequences showed hyper-intensity in the left hippocampus. 2 months after immunotherapy, a control cranial MRI showed a significant reduction of right hippocampus hyper-intensity in T2 weighted (C) and FLAIR (D) sequences.
case_images: fimmu-14-1191823-g002.jpg
case_images: PMC10248421_03_fimmu-14-1191823-g002.jpg
case_images: f2
case_images: Cognitive Assessment (MoCA) and 16/30 on the Mini-Mental State Examination (MMSE). Cranial MRI showed hyper-intensity on T2 and FLAIR sequence in the left hippocampus ( Figure 2 ).
case_images: PMC10248421_04
case_images: PMC10248421_05