case_images: PMC5811469_01
case_images: (A) Axial and (B) coronal 3 T MRI head scan shows blurry cortical gray and white matter on the left frontal lobe suggestive of focal cortical dysplasia (white arrow). Abbreviations: R, right; L, left.
case_images: fneur-09-00065-g001.jpg
case_images: PMC5811469_01_fneur-09-00065-g001.jpg
case_images: F1
case_images: A 28-year-old right-handed female presented to our service with neuroimaging findings compatible with frontal cortical dysplasia (Figure 1) refractory to AEDs.
case_images: (A) Sleep interictal scalp EEG shows epileptiform interictal discharges and focal slowing over the left fronto-central regions. Filters: 0.3-70 Hz. Notch: 60 Hz. Sensitivity: 7 microV/mm. (B) Ictal scalp video-EEG recording illustrates a clinical seizure onset over the left frontal central regions characterized by a fast and low voltage pattern with clonic right hemi-body seizures with Jacksonian march without loss of consciousness and preserved language. Filters: 1.0-35 Hz. Notch: 60 Hz. Sensitivity: 100 muVp-p.
case_images: fneur-09-00065-g002.jpg
case_images: PMC5811469_01_fneur-09-00065-g002.jpg
case_images: F2
case_images: A 10-h video-EEG recording showed 185 ictal (170 electrographic and 15 electro-clinical seizures) events of awake and sleep, mainly during sleep (10/15), characterized by brief focal clonic right hemi-facial seizures with or without Jacksonian march without loss of consciousness and preserved language, and with electrographic onset on the left fronto-central region; interictally showed 7-8 Hz background and 3-4 Hz focal slowing and epileptiform activity on the same region (Figure 2).