case_images: PMC5221465_01
case_images: Computed tomography scan. Solitary pulmonary nodule with an irregular margin.
case_images: RCR2-5-0-g001.jpg
case_images: PMC5221465_01_RCR2-5-0-g001.jpg
case_images: rcr2208-fig-0001
case_images: Computed tomography (CT) of the chest revealed a 3.1-cm pulmonary nodule with an irregular margin in the right middle lobe (Fig. 1).
case_images: Histolopathological and immunohistochemical examination of tissue sections. (A) Photomicrograph showing extensive lymphoplasmacytic infiltration with storiform fibrosis (haematoxylin and eosin staining, x100). (B) Photomicrograph showing infiltration of immunoglobulin (IgG)-positive plasma cells (IgG stain, x400). (C) Photomicrograph showing infiltration of immunoglobulin G4 (IgG4)-positive plasma cells (IgG4 stain, x400).
case_images: RCR2-5-0-g002.jpg
case_images: PMC5221465_01_RCR2-5-0-g002.jpg
case_images: rcr2208-fig-0002
case_images: Obliterative arteritis and phlebitis were also noted (Fig. 2A). Immunohistochemical staining indicated diffuse infiltration of IgG4-positive plasma cells, with an IgG4-positive/IgG-positive plasma cell ratio of 0.65 and an average number of 92 IgG4-positive plasma cells per high-power field (HPF) (Fig. 2B, C).