case_images: PMC11798677_01
case_images: Mild maculopapular rash on the face.
case_images: cureus-0017-00000078581-i01.jpg
case_images: PMC11798677_01_cureus-0017-00000078581-i01.jpg
case_images: FIG1
case_images: He presented painless lymphadenopathy in the right posterior cervical area and a mild maculopapular rash on his face without pruritus (Figure 1).
case_images: Oropharyngeal candidiasis and oral mucosal ulcerative lesions.
case_images: cureus-0017-00000078581-i02.jpg
case_images: PMC11798677_01_cureus-0017-00000078581-i02.jpg
case_images: FIG2
case_images: He also presented oropharyngeal candidiasis and oral mucosal ulcerative lesions (Figure 2).
case_images: A-C: Peripheral blood smear (May-Grunwald-Giemsa, x 1000) within 7-8% of neutrophils and monocytes yeast-like forms with an eccentric nucleus and an apparent pseudo capsule. Rare similar forms have also been observed extracellular. These visualised forms are suggestive of disseminated Histoplasmosis. The intracellular load was 1 to 10 organisms. D: White colonies with a cottony and sometimes warty appearance observed on the 18th day of culture. E: (Blue lactophenol, x1000) Microscopic exam of the colonies showing thick-walled single-celled macroconidia.
case_images: cureus-0017-00000078581-i03.jpg
case_images: PMC11798677_01_cureus-0017-00000078581-i03.jpg
case_images: FIG3
case_images: A peripheral blood smear revealed intracytoplasmic yeast cells consistent with H. capsulatum (Figure 3). Characteristic colonies and macroconidia of Histoplasma were observed, as described in Figure 3.