case_images: PMC11825224_01
case_images: Imaging studies.. (A, B) Urinary tract CT revealed an irregular, partial hyperreflective and reflective lesion growing through the bladder (white arrows). (C) A follow-up CT showing pulmonary metastasis.
case_images: cureus-0017-00000077414-i01.jpg
case_images: PMC11825224_01_cureus-0017-00000077414-i01.jpg
case_images: FIG1
case_images: Segmental thickening on the lateral side of the bladder was detected on computed tomography (CT) scans shown in Figure 1A and Figure 1B. A follow-up CT was performed 5 months after diagnosis and revealed multiple pulmonary metastases (Figure 1C). After five months, follow-up CT (Figure 1C) showed progressive pulmonary metastasis.
case_images: Histopathological picture.. The tumor showed anastomotic vascular spaces (A), lined by epithelioid tumor cells with high mitotic activity, and cytonuclear atypia (B), muscular invasion was prominent (C), the tumor cells are positive for ERG (D), CD31 (E), factor VIII (F) and c-myc (G).
case_images: cureus-0017-00000077414-i02.jpg
case_images: PMC11825224_01_cureus-0017-00000077414-i02.jpg
case_images: FIG2
case_images: The epithelioid tumor cells had markedly pleomorphic, vesicular nuclei, evident nucleoli, and moderate cytoplasm, as shown in Figures 2A, 2B, 2C. They were positive for ERG, CD34, CD31, factor VIII, and c-myc (Figure 2D, 2E, 2F, 2G), confirming the diagnosis of an epithelioid angiosarcoma.