case_images: PMC11027738_01
case_images: Patient's pharmacological treatment, EEG traces before and after fluoxetine therapy. Schematic representation of the proband's complex pharmacological treatment over time [legend of ASMs: acetazolamide (ACZ), carbamazepine (CBZ), clobazam (CLB), clonazepam (CNZ), diazepam (DZP), lamotrigine (LTG), methyl bromide (MB), nitrazepam (NZP), oxcarbazepine (OXC), topiramate (TPM)] (A). EEG trace assessed before fluoxetine treatment, showing diffuse, low-amplitude, theta background activity, and bitemporal epileptiform abnormalities with alternating prevalence of side (red squares, B). EEG during treatment with fluoxetine, revealing the improvement of background activity with alpha-slow rhythm of increased amplitude, together with disappearance of epileptic activity (C).
case_images: fncel-18-1367838-g001.jpg
case_images: PMC11027738_01_fncel-18-1367838-g001.jpg
case_images: fig1
case_images: Several antiseizure medications (ASMs) including lamotrigine, nitrazepam, oxcarbazepine, acetazolamide, and clonazepam, resulted ineffective (Figure 1A). EEG showed diffuse, low-amplitude, theta background activity, and bitemporal epileptiform abnormalities with alternating prevalence of side (Figure 1B).