case_images: PMC7270203_01
case_images: Painful, deep ulcer in the left buccal mucosa at age 26.
case_images: fimmu-11-00967-g0001.jpg
case_images: PMC7270203_01_fimmu-11-00967-g0001.jpg
case_images: F1
case_images: We first saw the patient at age 25 during the episode what the patient defined as the most severe attack of oropharyngeal ulceration (Figure 1).
case_images: (A) Pedigree of patient 1 and patient 2 (black arrows). (B) Novel heterozygous mutation affecting the DNA binding domain of STAT1 was detected in the patient and her daughter.
case_images: fimmu-11-00967-g0002.jpg
case_images: PMC7270203_01_fimmu-11-00967-g0002.jpg
case_images: F2
case_images: The baby of Patient 1 was breastfed for 6 months and she has had only mild gluteal and oral candidiasis after birth (Figure 2A).