case_images: PMC10726562_01
case_images: A: B-scan ultrasonography showing a mushroom-shaped mass protruding through the retina into the vitreous cavity, measuring 11.24 mm in the largest basal diameter and 6.56 mm in height. B: Sequence T1 and C: sequence T2 magnetic resonance imaging (MRI) showing a hyperintense and hypointense intraocular mass (yellow arrowhead), respectively, consistent with choroidal melanoma.
case_images: OC-13-22-g-001.jpg
case_images: PMC10726562_01_OC-13-22-g-001.jpg
case_images: F1
case_images: B-scan ultraso-nography demonstrated an infero-temporal retinal mass, mushroom-shaped, measuring 11.24x8.2x6.56 mm (Figure 1A (Fig. 1)). It showed a well-circumscribed mass with hyperintensity in sequence T1 and hypointensity in sequence T2, consistent with choroidal melanoma (Figure 1B and C (Fig. 1)).
case_images: A: Enucleated eye with a nodular amelanotic retinal mass with respect of underlying choroid and projecting into the vitreous cavity. B: A histopathologic image of the focal reactive nodular gliosis demonstrates that the tumor consists of a mass of spindle-shaped eosinophilic astrocytes (hematoxylin and eosin, 400 X). C: Note the abnormal sclerotic blood vessels with thickened and hyalinized wall (black arrow) (hematoxylin and eosin, 100 X). D: Immunohistochemistry for GFAP. Glial fibrillary acid protein is strongly expressed in the components of the spindle cells (glial tissue marker).
case_images: OC-13-22-g-002.jpg
case_images: PMC10726562_01_OC-13-22-g-002.jpg
case_images: F2
case_images: A nodular amelanotic mass was observed involving less than one quadrant of retina at equator with respect of underlying choroid and blurred overlying vitreous (Figure 2A (Fig. 2)). Numerous blood vessels with thickened and hyalinized wall were present as were hemorrhage foci (Figure 2B (Fig. 2)). Immunohistochemical stains showed intense positivity for glial fibrillary acid protein (GFAP) (Figure 2C (Fig. 2)) but not for S-100 protein.