case_images: PMC11711088_01
case_images: Mucolytics and their mechanisms of action.. HTS disrupts ionic bonds between mucoproteins, dissociates DNA from mucoproteins, and hydrates mucus via osmosis. NAC cleaves covalent disulfide bonds between mucoprotein monomers. Dornase alfa cleaves DNA polymers. HTS hypertonic saline, NAC N-acetylcysteine.
case_images: 41372_2024_2178_Fig1_HTML.jpg
case_images: PMC11711088_01_41372_2024_2178_Fig1_HTML.jpg
case_images: Fig1
case_images: Fig. 1 summarizes the mechanisms of action of the various mucolytic medications.