case_images: PMC10984360_01
case_images: Ultrasound reveals heterogeneous neoplastic lesion in the right testis
case_images: 2188-2126-69-5-0395-g001.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g001.jpg
case_images: g001
case_images: Ultrasound revealed heterogeneous neoplastic lesion in the central part of the right testis (Figure 1).
case_images: MRI reveals 2.7cm in diameter, clear boundary, and marginally smooth tumor in the right testis
case_images: 2188-2126-69-5-0395-g002.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g002.jpg
case_images: g002
case_images: MRI revealed 2.7cm clear boundary and marginally smooth tumor in the center of the testis (Figure 2).
case_images: A solid mass 1.5cm in diameter in the right testis
case_images: 2188-2126-69-5-0395-g003.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g003.jpg
case_images: g003
case_images: The cut surface showed a solid mass 1.5cm in diameter in the right testis (Figure 3).
case_images: H&E staining x 100. Lower part is hemorrhagic necrosis area. No tumor was seen in the bordering granulation tissue.
case_images: 2188-2126-69-5-0395-g004.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g004.jpg
case_images: g004
case_images: The granulation tissue intervened on the boundary line between necrosis and existing testicular tissue, but no findings suggestive of a tumor were obtained (Figure 4).
case_images: H&E staining x 200. Atypical cells do not extend beyond the basement membrane. Tumor cells are large, composed of a pale cytoplasm and large, irregular nuclei with well-defined nucleoli.
case_images: 2188-2126-69-5-0395-g005.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g005.jpg
case_images: g005
case_images: No extension to epididymis, vas deferens, and spermatic cord of atypical cells was seen (Figure 5).
case_images: MIB-1 staining x 100. The tumor cell nuclei stain blackish brown color. 30-40% are positive, indicating cancer.
case_images: 2188-2126-69-5-0395-g006.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g006.jpg
case_images: g006
case_images: The atypical cells were stained positively with immune-histochemical staining MIB-1 (Figure 6), CD117 (c-kit) (Figure 7) and D2-40 (Figure 8), but negatively with alpha-fetoprotein, human chorionic gonadotropin, and human chorionic gonadotropin-beta subunit.
case_images: KIT (CD117) staining x 100. The tumor cell cytoplasm stains brown color. Consistent with GCNIS diagnosis.
case_images: 2188-2126-69-5-0395-g007.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g007.jpg
case_images: g007
case_images: The atypical cells were stained positively with immune-histochemical staining MIB-1 (Figure 6), CD117 (c-kit) (Figure 7) and D2-40 (Figure 8), but negatively with alpha-fetoprotein, human chorionic gonadotropin, and human chorionic gonadotropin-beta subunit.
case_images: D2-40 (podoplanin) staining x 100. The tumor cell membrane stains brown color. Consistent with GCNIS diagnosis.
case_images: 2188-2126-69-5-0395-g008.jpg
case_images: PMC10984360_01_2188-2126-69-5-0395-g008.jpg
case_images: g008
case_images: The atypical cells were stained positively with immune-histochemical staining MIB-1 (Figure 6), CD117 (c-kit) (Figure 7) and D2-40 (Figure 8), but negatively with alpha-fetoprotein, human chorionic gonadotropin, and human chorionic gonadotropin-beta subunit.