case_images: PMC2631530_01
case_images: CT slice showing new lesion in oropharynx.
case_images: 1757-1626-2-3-1.jpg
case_images: PMC2631530_01_1757-1626-2-3-1.jpg
case_images: F1
case_images: As a result of ongoing odynophagia, a repeat CT scan was requested at a further 2 month interval (nine months after the onset of symptoms) which revealed a new lesion in the oropharynx [fig 1] and significant adenopathy within the neck (cervical and supraclavicular lymph nodes), more marked on the left than right.
case_images: Biopsy of oropharnyx confirming submucosal metastatic invasive ductal carcinoma.
case_images: 1757-1626-2-3-2.jpg
case_images: PMC2631530_01_1757-1626-2-3-2.jpg
case_images: F2
case_images: Subsequent examination under anaesthetic and biopsy of the area confirmed submucosal metastatic invasive ductal carcinoma with some lobular differentiation [fig 2].
case_images: E-cadherin stain on oropharyngeal biopsy.
case_images: 1757-1626-2-3-3.jpg
case_images: PMC2631530_01_1757-1626-2-3-3.jpg
case_images: F3
case_images: E-Cadherin staining showed strong expression within the majority of the tumour cells [fig 3].