case_images: PMC8558305_01
case_images: CT image of primary sinonasal SDC tumor (indicated by black arrows).
case_images: fmed-08-730403-g0001.jpg
case_images: PMC8558305_01_fmed-08-730403-g0001.jpg
case_images: F1
case_images: Additional imaging examinations revealed a large sinonasal process (Figure 1).
case_images: Photomicrographs of case report 1: cervical lymph node containing an SDC metastasis. (A) H&E stain 1X, (B) H&E stain 10X, (C) H&E stain 21X, (D) AR stain 20X, AR441 (BioCare Medical), (E) HER2neu stain 21X, HercepTest (Dako Agilent).
case_images: fmed-08-730403-g0002.jpg
case_images: PMC8558305_01_fmed-08-730403-g0002.jpg
case_images: F2
case_images: The tumor cells were positive for androgen receptor (AR) (see Figure 2).
case_images: Time-line of case report 1.
case_images: fmed-08-730403-g0003.jpg
case_images: PMC8558305_01_fmed-08-730403-g0003.jpg
case_images: F3
case_images: Apart from Cr(VI) exposure, the patient may have come into contact with other chemical substances during a previous occupation (Figure 3).
case_images: PMC8558305_02
case_images: CT image of primary submandibular SDC tumor (indicated by white arrows).
case_images: fmed-08-730403-g0004.jpg
case_images: PMC8558305_02_fmed-08-730403-g0004.jpg
case_images: F4
case_images: PET/CT imaging showed a primary tumor originating from the right submandibular gland (Figure 4) and also right lymphadenopathy at level I-V, suspect for lymph node metastases, and a lesion in the 3rd thoracic vertebra.
case_images: Photomicrographs of case report 2: biopsy of SDC bone metastasis in thoracic vertebra 3. 1. (A) H&E stain 1X, (B) H&E stain 10X, (C) H&E stain 20X, (D) AR stain 5X (photomicrograph from referring center), (E) HER2neu stain 10X, HercepTest (Dako Agilent).
case_images: fmed-08-730403-g0005.jpg
case_images: PMC8558305_02_fmed-08-730403-g0005.jpg
case_images: F5
case_images: Biopsy of the bone lesion revealed a SDC metastasis (T2N2bM1 disease) (Figure 5).
case_images: Time-line of case report 2.
case_images: fmed-08-730403-g0006.jpg
case_images: PMC8558305_02_fmed-08-730403-g0006.jpg
case_images: F6
case_images: In addition to Cr(VI) exposure, the patient may have come into contact with other chemical substances (Figure 6).