case_images: PMC11786691_01
case_images: Gross image, skin surface, swelling-like growth, grayish-white, grayish-black, nodular protrusion with local surface ulceration.
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case_images: The tumor exhibited infiltrative growth beneath the skin, with visible fat infiltration, without involvement of the jawbone (as shown in Fig. 1, Fig. 2).
case_images: HE image, 200x magnification, the tumor is located in the subcutaneous dermis layer, consisting of arborizing blood vessels arranged in a testicular network pattern, lined with vascular endothelium resembling boot spikes; red blood cells are visible in the lumen, and local intraluminal papillary structures can be seen, similar to Dabska's tumor. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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case_images: The tumor cells had lightly stained or eosinophilic cytoplasm, typically with less cytoplasmic content, a high nuclear-to-cytoplasmic ratio, and a transition between tumor cells and reticular vessels (Fig. 3, Fig. 4, Fig. 5, Fig. 6).
case_images: HE image, 200x magnification, the tumor grows in a solid nest-like, strip-like, and cord-like pattern, with whirlpool-like arrangement, vascular endothelial cell nuclei are round or oval, small nucleoli are visible, the cytoplasm is acidophilic and contains less cytoplasmic content, cell boundaries are unclear, and some cytoplasm appears vacuolated. Cytological atypia is minimal, mitotic figures are virtually absent, and the tumor infiltrates among collagen fibers in the dermis.
case_images: gr5.jpg
case_images: PMC11786691_01_gr5.jpg
case_images: f0025
case_images: The tumor cells had lightly stained or eosinophilic cytoplasm, typically with less cytoplasmic content, a high nuclear-to-cytoplasmic ratio, and a transition between tumor cells and reticular vessels (Fig. 3, Fig. 4, Fig. 5, Fig. 6).
case_images: Immunohistochemistry image, CD31, 200x magnification, positive tumor vascular endothelial cells.
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case_images: PMC11786691_01_gr7.jpg
case_images: f0035
case_images: Tumor cells expressed vascular endothelial markers such as CD31 (as shown in Fig. 7), CD34 (as shown in Fig. 8), ERG, and D2-40, with a high Ki67 proliferation index of approximately 40 %, and interstitial
case_images: Immunohistochemistry image, 200x magnification, showing CD3 positive expression of T lymphocytes in the stroma.
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case_images: PMC11786691_01_gr9.jpg
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case_images: T lymphocytes expressed CD3 immunomarkers (as shown in Fig. 9). The work has been reported in line with the SCARE criteria.