case_images: PMC10963102_01
case_images: Intraoral photographs of the patient showing the widespread, corrugated, and slightly stippled white lesions with a spongy texture on the (a) right buccal mucosa, (b) upper and lower gingiva, and (c) left buccal mucosa.
case_images: CRID2024-2251450.001.jpg
case_images: PMC10963102_01_CRID2024-2251450.001.jpg
case_images: fig1
case_images: A clinical examination showed irregular white plaques with well-defined borders and multiple localizations on the buccal mucosa, gingiva, and mucobuccal folds of the upper and lower jaws, with different densities in places (Figure 1).
case_images: (a) The acanthosis and parakeratosis of the squamous epithelium (hematoxylin and eosin stain, x10); (b) the extensive vacuolization of suprabasal keratinocytes (hematoxylin and eosin stain, x40); (c) keratinocytes with dense perinuclear eosinophilic condensation due to the aggregation of intermediate filaments (hematoxylin and eosin stain, x40).
case_images: CRID2024-2251450.002.jpg
case_images: PMC10963102_01_CRID2024-2251450.002.jpg
case_images: fig2
case_images: A histological examination of the lesions revealed squamous epithelium with hyperparakeratosis and acanthosis, which had elongated rete ridges and scarce lymphocytic presence in the subepithelial connective tissue (Figure 2(a)). A characteristic finding was the vacuolization of suprabasal keratinocytes and dyskeratotic cells with dense perinuclear eosinophilic condensation, demonstrating cytokeratin filament aggregation (Figures 2(b) and 2(c)).