case_images: PMC11794817_01
case_images: The condition of muscle weakness of the patient. (A) Overall condition of the patient, underweight. (B) Double lower limb muscular atrophy.
case_images: fmed-11-1481780-g001.jpg
case_images: PMC11794817_01_fmed-11-1481780-g001.jpg
case_images: fig1
case_images: A 33-year-old male with no significant past medical history presented with a five-year history of weight loss and decreased muscle strength in the lower extremities (Figure 1), accompanied by 6 months of bowel symptoms, including mucopurulent blood stools and increased stool frequency.
case_images: Colonoscopic and pathological manifestations of intestinal damage. (A) Inflammation and ulcers in the rectum. (B) Disturbed crypt structure with lymphocytic plasma cell sheet proliferation at the base of the mucosa. (C) The saphenous fossa is atrophied and reduced in number, with a widening of the spacing between the base of the saphenous fossa and the mucosal layer and a reduction in the epithelial cup cells in some of the saphenous fossae. (D) Crypt fossa branching, irregular.
case_images: fmed-11-1481780-g002.jpg
case_images: PMC11794817_01_fmed-11-1481780-g002.jpg
case_images: fig2
case_images: Based on the combined clinical evidence available to date, including but not limited to serology, endoscopy, and histopathology, the intestinal manifestations were ultimately caused by UC (Figure 2).