case_images: PMC11003595_01
case_images: H&E-stained image showing focal mesangial proliferation and capillary lumen filled with red blood cells. H&E = hematoxylin and eosin 20X.
case_images: IJN-34-059-g001.jpg
case_images: PMC11003595_01_IJN-34-059-g001.jpg
case_images: F1
case_images: The fluorescence in situ hybridization (FISH) test was positive for 13q14.2 and negative for deletion 6q, deletion 11 q, trisomy 12, Immunoglobulin heavy chain locus (IGH) rearrangement, and deletion 17p [Figures 1 to 5].
case_images: Electron microscopy showing significant foot process effacement. Several mesangial and paramesangial areas showing aggregates of nonbranching, randomly orientedfibrils. No electron dense deposits identified.
case_images: IJN-34-059-g002.jpg
case_images: PMC11003595_01_IJN-34-059-g002.jpg
case_images: F2
case_images: The fluorescence in situ hybridization (FISH) test was positive for 13q14.2 and negative for deletion 6q, deletion 11 q, trisomy 12, Immunoglobulin heavy chain locus (IGH) rearrangement, and deletion 17p [Figures 1 to 5].
case_images: Glomerulus and blood vessel showing deposits of pale staining amorphous material (amyloid) on H and E stain. H&E = hematoxylin and eosin.
case_images: IJN-34-059-g003.jpg
case_images: PMC11003595_01_IJN-34-059-g003.jpg
case_images: F3
case_images: The fluorescence in situ hybridization (FISH) test was positive for 13q14.2 and negative for deletion 6q, deletion 11 q, trisomy 12, Immunoglobulin heavy chain locus (IGH) rearrangement, and deletion 17p [Figures 1 to 5].
case_images: Aggregates of randomly oriented fibrillary structures on electron microscopy.
case_images: IJN-34-059-g004.jpg
case_images: PMC11003595_01_IJN-34-059-g004.jpg
case_images: F4
case_images: The fluorescence in situ hybridization (FISH) test was positive for 13q14.2 and negative for deletion 6q, deletion 11 q, trisomy 12, Immunoglobulin heavy chain locus (IGH) rearrangement, and deletion 17p [Figures 1 to 5].
case_images: Markedly expanded mesangial and subendothelial areas occupied by aggregates of randomly oriented, nonbranching fibrillary structures measuring about 9-12 nm in diameter (mean fibril diameter 10.8 nm) with focal "streaming" arrangement. CyBorD = cyclophosphamide, bortezomib, and dexona, GN = glomerulonephritis.
case_images: IJN-34-059-g005.jpg
case_images: PMC11003595_01_IJN-34-059-g005.jpg
case_images: F5
case_images: The fluorescence in situ hybridization (FISH) test was positive for 13q14.2 and negative for deletion 6q, deletion 11 q, trisomy 12, Immunoglobulin heavy chain locus (IGH) rearrangement, and deletion 17p [Figures 1 to 5].
case_images: PMC11003595_02
case_images: PMC11003595_03
case_images: PMC11003595_04