case_images: PMC11528893_01
case_images: Hematoxylin-eosin staining. A: Showed CK (-), CD38 (+), CD138 (+), EMA (+), CyclinD1 (-), k (-), lambda (+), CD20 (-), CD68 (-), Ki-67 (5%+), CD56 (-), EBER (-), CD10 (-), MUM-1 (+), Bcl-2 (partially+), Bcl-6 (-), p63 (-), WIM (+), S-100 (-), CD79a (+), CD3 (-), CgA (-), SYN (-), EGFR (-), and MyoD1 (-); B: A small number of nested growth plasma cell-like cells were seen in the tissue sent for examination. With some heterogeneity, combined with the immunohistochemical results, a plasma cell tumor was considered.
case_images: 96131-g001.jpg
case_images: PMC11528893_01_96131-g001.jpg
case_images: F1
case_images: Further immunohistochemical analysis of the specimens showed positivity for the plasma cell markers CD38 and CD138, while CD20 and CD3 were negative (Figure 1).
case_images: Magnetic resonance imaging images showing a uvula mass (orange arrow) and the uvula (blue arrow). A: February 2023; B: April 2023.
case_images: 96131-g002.jpg
case_images: PMC11528893_01_96131-g002.jpg
case_images: F2
case_images: Magnetic resonance imaging (MRI) of the oropharynx showed an irregular, sharply defined soft tissue mass measuring 1.8 cm x 1.9 cm x 2.2 cm with heterogeneous enhancement (Figure 2A).