case_images: PMC10959544_01
case_images: Biomicroscopy of the right anophthalmic socket of the patient.
case_images: cop-2024-0015-0001-535598_F01.jpg
case_images: PMC10959544_01_cop-2024-0015-0001-535598_F01.jpg
case_images: F1
case_images: Ophthalmological evaluation revealed a thickened bulbar conjunctiva with a central translucid round area, vascularized, and an associated inferior symblepharon (Fig. 1).
case_images: Orbital MRI revealing a cyst-like structure on the right orbit.
case_images: cop-2024-0015-0001-535598_F02.jpg
case_images: PMC10959544_01_cop-2024-0015-0001-535598_F02.jpg
case_images: F2
case_images: There was a structure with a T1 signal which was identical to an atrophied optic nerve, and there was no contrast uptake that indicated an expanding lesion (Fig. 2). These exams were compared with previous orbital CT from 6 years before (after a trauma incident), in which the lesion was not apparent.
case_images: CT of the same patient 6 years earlier, with the hyperdensity of the prothesis and normal right orbit volume.
case_images: cop-2024-0015-0001-535598_F03.jpg
case_images: PMC10959544_01_cop-2024-0015-0001-535598_F03.jpg
case_images: F3
case_images: Drainage of the cystic content and biopsy with partial resection were performed (Fig. 3).
case_images: Giant conjunctival cyst of the orbit. The histopathological analysis of the biopsy material showed tissue fragments lined by multilayered cuboidal non-keratinized epithelium, without goblet cells (H&E, a x200 magnification; b x400 magnification); and tissue fragments lined by multilayered cuboidal epithelium, focally having goblet cells (yellow asterisk), compatible with conjunctival type epithelium (H&E, c x200 magnification; d x400 magnification). Foci of squamous, non-keratinizing epithelium were also present in some of the tissue fragments (H&E, c x200 magnification; d x400 magnification). In a subepithelial location, there was a mild to moderate chronic inflammatory infiltrate and mild fibrosis. There were neither signs of dysplasia nor of carcinoma structures. There was also no evidence of the previously diagnosed retinoblastoma. The morphological findings are compatible with a conjunctival cyst.
case_images: cop-2024-0015-0001-535598_F04.jpg
case_images: PMC10959544_01_cop-2024-0015-0001-535598_F04.jpg
case_images: F4
case_images: Pathology exam revealed fragments of fibrous tissue with a cystic structure covered with conjunctival-like epithelium, with no evidence of dysplasia or malignancy (Fig. 4).