case_images: PMC10282535_01
case_images: (A) CT chest of the patient with the 12 cm diameter left-sided fungating breast mass shown at the time of initial diagnosis. (B) Tumor visualized after progressing through initial line of paclitaxel chemotherapy and right before initiating FAST-Forward radiation therapy. (C) Radiotherapy plan with prescribed dose of 26 Gy in 5 fractions with a 0.5 cm bolus. (D) CT chest showing the 1.8 cm tumor 3.5 months after completion of radiation therapy and starting doxorubicin chemotherapy.
case_images: fonc-13-1171444-g001.jpg
case_images: PMC10282535_01_fonc-13-1171444-g001.jpg
case_images: f1
case_images: Figure 1A ), abnormally enhancing axillary and retropectoral lymph nodes, and multiple non-specific pulmonary nodules. Further staging examinations included a nuclear bone scan which revealed a focus of increased activity in the sacrum, consistent with metastases. After 3 cycles of doxorubicin, her follow-up chest CT revealed an increase in size of the left breast mass as well as of the pulmonary nodules ( Figure 1B ). Doxorubicin was stopped and the patient underwent ultrahypofractionated radiation therapy to the whole left breast with 26 Gy over 5 fractions ( Figure 1C ). This chest CT taken 3.5 months after completion of the ultrahypofractionated radiation therapy showed that the mass had significantly reduced and measured 0.8 cm by 1.8 cm ( Figure 1D ).