case_images: PMC9068340_01
case_images: Characteristic crazy paving pattern in a patient referred to lung transplantation because of Niemann-Pick type B disease.
case_images: CRIT2022-5428381.001.jpg
case_images: PMC9068340_01_CRIT2022-5428381.001.jpg
case_images: fig1
case_images: He had extensive pulmonary involvement at chest computed tomography (CT) with a diffuse interstitial disease and a radiological pattern of "crazy paving" in the lower and middle lung fields (Figure 1).
case_images: Macroscopic view of the explanted lungs.
case_images: CRIT2022-5428381.002.jpg
case_images: PMC9068340_01_CRIT2022-5428381.002.jpg
case_images: fig2
case_images: Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).
case_images: Microscopic section of lung parenchyma. Morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of Niemann-Pick disease.
case_images: CRIT2022-5428381.003.jpg
case_images: PMC9068340_01_CRIT2022-5428381.003.jpg
case_images: fig3
case_images: Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).
case_images: At higher magnification, foamy histiocytes.
case_images: CRIT2022-5428381.004.jpg
case_images: PMC9068340_01_CRIT2022-5428381.004.jpg
case_images: fig4
case_images: Histopathologic findings in the explant lungs revealed a morphological pattern of unclassifiable interstitial pneumonia with foamy histiocytes suggestive of NPD (Figures 2-4).