case_images: PMC6719345_01
case_images: Light microscopy: presence of PAS-positive coagula of cryoglobulin in the glomerular capillaries and arterioles (arrowheads).
case_images: CRIN2019-7940291.001.jpg
case_images: PMC6719345_01_CRIN2019-7940291.001.jpg
case_images: fig1
case_images: Many glomeruli contained PAS-positive intracapillary coagula of cryoglobulin (Figure 1), and small double contours were observed on silver stain.
case_images: Immunofluorescence microscopy: Kappa light chain deposits within the glomerulus. Lambda light chain is negative.
case_images: CRIN2019-7940291.002.jpg
case_images: PMC6719345_01_CRIN2019-7940291.002.jpg
case_images: fig2
case_images: IF and revealed the following findings: IgM, Kappa, and C3 (3+) granular staining along peripheral capillary loops (Figure 2); IgG and Lambda (negative to trace) staining in the glomeruli. IgA, C1q, and Albumin were negative.
case_images: Electron microscopy: subendothelial and subepithelial electron dense deposits of cryoglobulins (arrowheads).
case_images: CRIN2019-7940291.003.jpg
case_images: PMC6719345_01_CRIN2019-7940291.003.jpg
case_images: fig3
case_images: Electron microscopy (EM): endocapillary proliferation, mesangial interposition, and presence of subendothelial and subepithelial electron dense deposits were observed in the single glomerulus present for electron microscopy (Figure 3).