case_images: PMC11182326_01
case_images: Composite photograph showing slit lamp photograph with a total cataract in the right eye (A) and pseudophakia in the left eye (B); a color fundus photograph of the left eye showing vitritis, vitreous membranes, and multiple areas of retinitis with sheathing of arteries and veins (C); external photograph showing annual erythematous lesions on the abdomen (D); a fundus photograph of left eye 1 week after the initiation of systemic antifungals showing decreased vitreous haze (E); and cytology of the vitreous biopsy showing a few lymphocytes and macrophages (F).
case_images: fopht-03-1174414-g001.jpg
case_images: PMC11182326_01_fopht-03-1174414-g001.jpg
case_images: f1
case_images: Her skin lesions had started healing at 1 week with a marginal improvement in vision [BCVA 2/60 in the left eye] and a decrease in vitreous haze in left eye to 2+ with better appreciation of retinal details. ( Figure 1 ) The total WBC counts also decreased to 12,000 cells/mm3.
case_images: Composite photograph showing a fundus photograph of left eye 1 month after vitrectomy (A) with resolving retinitis with sheathing around the arteries (white arrow head) and veins (red arrow head); optical coherence tomography (OCT) over the retinitis (B) inferior to the fovea showing hyperreflectivity of the retina (white arrow); OCT over the healed retinitis lesion nasal to the disc showing disorganization of the inner retinal layer (C); OCT angiogram showing a flow void area nasal to the disc corresponding to area of healed retinitis (D) and at the macula showing a flow void area (yellow arrow head) corresponding to area of retinitis (E); OCT over the healed retinitis lesion superior to macula showing hyperreflectivity of the retina and involvement of choroid (F); an external photograph showing healed skin lesions over the hand with hyperpigmentation at the 6-month follow-up (G); and a fundus photograph of left eye at the 6-month follow-up showing resolved inflammation and chorioretinal scars.
case_images: fopht-03-1174414-g002.jpg
case_images: PMC11182326_01_fopht-03-1174414-g002.jpg
case_images: f2
case_images: After 4 weeks, her BCVA had improved to 6/24 in left eye, with healing retinochoroiditis lesions and peripapillary atrophy. ( Figure 2 ) The antifungal medications were continued for 3 months, and the dose of methotrexate was reduced to 15 mg/week.