case_images: PMC8591280_01
case_images: Patients clinical course from admission to our university medical center intensive care unit (ICU). Dexamethasone therapy is shown in yellow; Interferon-y-therapy is shown in red and antibiotics are shown in blue.
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case_images: PMC8591280_01_fimmu-12-753849-g001.jpg
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case_images: Table 1 ) are shown. The diagnosis of severe sepsis was confirmed by the detection of multiple bacterial species: four different multidrug-resistant 4MRGN species were detected in blood cultures (Klebsiella pneumoniae) and in tracheal fluids (Pseudomonas aeruginosa, Acinetobacter baumanii, Enterococcus faecalis) (see  Figure 1  and  Table 2 ).
case_images: Chest X-ray of the patient immediately before interferon administration at week 4 (A) and after administration and clinical improvement at week 6 (B).
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case_images: PMC8591280_01_fimmu-12-753849-g002.jpg
case_images: f2
case_images: Table 1 ) are shown. The diagnosis of severe sepsis was confirmed by the detection of multiple bacterial species: four different multidrug-resistant 4MRGN species were detected in blood cultures (Klebsiella pneumoniae) and in tracheal fluids (Pseudomonas aeruginosa, Acinetobacter baumanii, Enterococcus faecalis) (see  Figure 1  and  Table 2 ). Chest radiographs and computed tomography scans revealed severe persistent ARDS with extensive pulmonary infiltrates (See  Figure 2 ).