case_images: PMC9547027_01
case_images: PMC9547027_02
case_images: gross examination of the specimen showing a white beige neoplasm, encapsulated, with yellowish, necrotic and hemorrhagic areas (blue arrow)
case_images: PAMJ-42-206-g001.jpg
case_images: PMC9547027_02_PAMJ-42-206-g001.jpg
case_images: F1
case_images: Diagnosis: the gross examination of the specimen revealed a white beige neoplasm, encapsulated, measuring 19x18x17 cm, with yellowish, necrotic and hemorrhagic areas (Figure 1).
case_images: histological examination, hematoxylin and eosin stain, (A, 10x) and (B, 20x) showing the chromophobe renal cell carcinoma and high-grade sarcomatous component with sheets lipoblasts pleomorphics
case_images: PAMJ-42-206-g002.jpg
case_images: PMC9547027_02_PAMJ-42-206-g002.jpg
case_images: F2
case_images: The histopathological examination showed two distinct morphologic components, chromophobe renal cell carcinoma and sarcomatous component (Figure 2): the sarcomatous component was predominant and constituted of sheets lipoblasts pleomorphics with micro and macrovacuolated cytoplasms notching the nuclei in concave way.
case_images: immunohistochemistry, (A, 20x) and (B, 40x); chromophobe renal cell carcinoma showing positive reactivity for cytokeratin AE1/AE3
case_images: PAMJ-42-206-g003.jpg
case_images: PMC9547027_02_PAMJ-42-206-g003.jpg
case_images: F3
case_images: Immunohistochemically, Chromophobe renal cell carcinoma cells were positive for cytokeratin AE1/AE3 and cytokeratin 7 (Figure 3).