case_images: PMC11061434_01
case_images: Imaging findings at the initial examination, (A), CT; (B), (C): MRI; (D), MRA. Bilateral involvement of the globus pallidus and abnormalities in the right cerebellar hemisphere are evident. No major vessel stenosis is observed. CT, computed tomography; MRI, magnetic resonance imaging; MRA, magnetic resonance angiography.
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case_images: PMC11061434_01_fmed-11-1364038-g0001.jpg
case_images: F1
case_images: Initial magnetic resonance imaging (MRI) revealed abnormal intensities in the bilateral globus pallidus and cerebellum (Figure 1).
case_images: Clinical course of the patient. Circle, HBO; square, MRI taken; diamond, MMSE score. ADL, activities of daily living; DPHL, delayed post-hypoxic leukoencephalopathy; GCS, Glasgow Coma Scale; HBO, hyperbaric oxygen; MMSE, Mini-Mental State Examination; MRI, magnetic resonance imaging.
case_images: fmed-11-1364038-g0002.jpg
case_images: PMC11061434_01_fmed-11-1364038-g0002.jpg
case_images: F2
case_images: Although HBO was sometimes interrupted, the patient received 63 HBO treatments (Figure 2; Supplementary Video).
case_images: The course of MRI findings. (A) day 11; (B) day 25; (C) day 38; (D) day 89; (E) day 165. White matter abnormalities become apparent from day 25 and gradually disappear after consecutive HBO therapy. HBO, hyperbaric oxygen; MRI, magnetic resonance imaging.
case_images: fmed-11-1364038-g0003.jpg
case_images: PMC11061434_01_fmed-11-1364038-g0003.jpg
case_images: F3
case_images: HBO, MRI revealed a gradual disappearance of white matter abnormality (Figure 3). However, hypoperfusion in the frontal lobe detected on N-isopropyl-p-[123I]-iodoamphetamine single-photon emission computed tomography (123I-IMP-SPECT) that appeared during the course, remained evident (Figure 4).
case_images: 123I-IMP SPECT findings. (A) day 12; (B) day 96; (C) day 164. The frontal lobe hypoperfusion is apparent on day 96 and persists. 123I-IMP SPECT, N-isopropyl-p-[123I]- iodoamphetamine single-photon emission computed tomography.
case_images: fmed-11-1364038-g0004.jpg
case_images: PMC11061434_01_fmed-11-1364038-g0004.jpg
case_images: F4
case_images: HBO, MRI revealed a gradual disappearance of white matter abnormality (Figure 3). However, hypoperfusion in the frontal lobe detected on N-isopropyl-p-[123I]-iodoamphetamine single-photon emission computed tomography (123I-IMP-SPECT) that appeared during the course, remained evident (Figure 4).