case_images: PMC11018878_01
case_images: (A, B): Significant thickening of the gastric wall at the antrum was seen before neoadjuvant therapy. (C, D): Significant reduction of visible primary foci and lymph nodes at the gastric antrum after neoadjuvant therapy. (E): Macroscopic presentation of the resected stomach with extensive tumour invasion of the stomach.
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case_images: CT scans revealed enlarged lymph nodes in the lesser curvature of the stomach ( Figures 1A-D ). The tumor presented with an ulcerated infiltrate and irregularities in the surrounding mucosa, involving the gastric serosa layer ( Figure 1E ).
case_images: Intraoperative blood pressure fluctuated, with most of the time it was located above 140 mmHg, reaching a maximum of 240 mmHg.
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case_images: However, the patient's blood pressure continued to fluctuate during the operation, with readings consistently exceeding 140 mmHg, and reaching as high as 240 mmHg ( Figure 2 ).
case_images: (A, B): HE staining of the tumor showed diffuse growth of paraganglioma cells with moderately to poorly differentiated tubular adenocarcinoma. (C): INSM1 immunohitochemistry shows strong positivity. (D): AE1/AE3 immunohistochemistry shows strong positivity. (E): CgA immunohistochemistry shows focal positivity. (F): CD56 immunohistochemistry shows negativity.
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case_images: f3
case_images: CK (AE1/AE3), CgA, and INSM1 staining were positive, while Syn and CD56 staining were negative ( Figures 3 A-F ).