case_images: PMC2905698_01
case_images: Panel (a) shows an area of invasive, keratinizing squamous cell carcinoma that has infiltrated beyond the muscularis propria (detrusor muscle) and into the perivesical adipose tissue. There is an associated desmoplastic reaction to the tumor. Panel (b) demonstrates the extensive squamous metaplasia seen in the background benign urothelium. Adjacent to the invasive tumor were foci of squamous cell carcinoma in situ (Panel (c)). Original magnification:200x (panel (a)), 400x (panels (b), and (c)).
case_images: AU2010-179250.002.jpg
case_images: PMC2905698_01_AU2010-179250.002.jpg
case_images: fig2
case_images: The adjacent bladder mucosa showed focal squamous cell carcinoma in situ and extensive squamous metaplasia of the surrounding benign urothelium (Figure 2).