case_images: PMC11782956_01
case_images: Plain and contrast enhanced computed tomography scans of the abdomen. Preoperative images: (A, B) A uneven thickening of the jejunum in the left epigastric region (red box). (C, D) The liver had no obvious abnormalities. Postoperative images: (E, F) A jejunal anastomotic mass with 3.1 cm x 2.4cm of diameter (red box) and multiple nodular masses in the abdominopelvic region, omentum (yellow arrow). (G, H) Scattered circular mass in the liver (yellow arrow).
case_images: fonc-14-1519968-g001.jpg
case_images: PMC11782956_01_fonc-14-1519968-g001.jpg
case_images: f1
case_images: Computed tomography scan of the abdomen showed localized uneven thickening of the jejunum in the left epigastric region, suspicious for a neoplastic lesion ( Figures 1A, B ). There are no obvious abnormalities in the liver except for hepatic cysts ( Figures 1C, D ). In April 2024, postoperative CT revealed jejunal anastomotic mass ( Figures 1E, F ) with multiple metastases found in the abdominopelvic region, omentum, and liver ( Figures 1G, H ), suggestive of recurrent neoplastic disease.
case_images: Histological analysis of malignant glomus tumor in the jejunum. Hematoxylin-eosin (HE): (A) The tumor cells showed a nested growth pattern (magnification, 40x). (B) Relatively uniform tumor cells distributed around mildly dilated, thin-walled vessels (magnification, 100x). (C) The tumor cells exhibited an epithelioid morphology, round to oval nuclei and obvious nuclear atypia (magnification, 200x). (D) There was increased mitosis (red arrow) (magnification, 400x). Immunohistochemistry: (E) Vimetin positivity. (F) Strong positive for smooth muscle actin. (G) Collagen IV positivity. (H) Negative for desmin. (I) Ki-67 proliferative index of 20%.
case_images: fonc-14-1519968-g002.jpg
case_images: PMC11782956_01_fonc-14-1519968-g002.jpg
case_images: f2
case_images: Histopathological examination showed a nested growth pattern of relatively uniform tumor cells, interspersed with occasionally mildly dilated, thin-walled vessels encircled by tumor cells ( Figures 2A, B ). There was obvious nuclear atypia and mitosis like 15/50 HPF ( Figures 2C, D ). IV ( Figure 2G ), with a Ki-67 proliferative index of 20% ( Figure 2I ). It was negative for desmin ( Figure 2H ).