case_images: PMC9938400_01
case_images: Radiologic and gross findings. a A contrast-enhanced magnetic resonance imaging (MRI) scan showing well-circumscribed tumors up to 7.5 cm in the scrotum (yellow arrows). b The surgically resected specimen. The tumors were 9.0 x 8.0 x 5.5 cm (right) and 5.0 x 4.0 x 3.8 cm (left) in size. c, d Cut surface of the resected specimen. The tumors had a white whorled appearance and separate from the testes.
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case_images: F1
case_images: Contrast-enhanced magnetic resonance imaging scan revealed well-circumscribed tumors of up to 7.5 cm in size in the scrotum with heterogeneous enhancement (Fig. 1a). Gross examination revealed a solid gray-white, well-circumscribed, firm mass (Fig. 1b). These tumors were separate from the testes, which appeared brownish in color (Fig. 1c, d).
case_images: Histopathological findings. Magnification: x40 (a), x100 (b), and x400 (c). a The tumor formed a fascicular growth pattern with no necrosis or bleeding. b The tumors were formed by interlacing bundles separated by well-vascularized connective tissue. c The tumor cells contained oval to spindle nuclei and acidophilic cytoplasm.
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case_images: F2
case_images: Histological examination showed that the tumors were well demarcated and eosinophilic (Fig. 2a). The tumors were formed by interlacing bundles of smooth muscle cells separated by numerous well-vascularized connective tissue (Fig. 2b). The tumor cells had oval to spindle-shaped nuclei and acidophilic cytoplasm (Fig. 2c).
case_images: Immunohistochemical findings. a HE. b alphaSMA. c S100a. d CD34. e c-kit. f Ki-67. Magnification: (a-f) x400.
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case_images: F3
case_images: Immunohistochemically, the tumor cells were positive for alpha-smooth muscle actin and negative for S-100a, CD34, and c-kit (Fig. 3a-e). The Ki-67 positivity rate was less than 1% (Fig. 3f).