case_images: PMC9586834_01
case_images: T1 and T2 FLAIR sections of magnetic resonance imaging show hyper signal intensity involving the bilateral hypothalamus.
case_images: CRIN2022-6120644.001.jpg
case_images: PMC9586834_01_CRIN2022-6120644.001.jpg
case_images: fig1
case_images: T2/FLAIR lesion involving the bilateral hypothalamus with modest perilesional edema (Figure 1). The pathology of the thyroid and lymph node biopsies revealed aggregation of histiocyte-like cells, some of which had nuclear grooves. The immunohistochemistry was positive for CD1a and
case_images: The core biopsy shows the aggregation of histiocyte-like cells, some of which show nuclear grooves. Mitosis and necrosis are not observed.
case_images: CRIN2022-6120644.002.jpg
case_images: PMC9586834_01_CRIN2022-6120644.002.jpg
case_images: fig2
case_images: S100, which was compatible with Langerhans cell histiocytosis (LCH) (Figure 2). She had no family history of LCH.
case_images: Time course of sodium levels.
case_images: CRIN2022-6120644.003.jpg
case_images: PMC9586834_01_CRIN2022-6120644.003.jpg
case_images: fig3
case_images: Her serum sodium level had returned to normal after three days.  Figure 3 demonstrates the time course of the serum sodium concentration.