case_images: PMC10955048_01
case_images: Minocycline-induced drug reaction with eosinophilia and systemic symptoms. (A) Diffuse erythematous or maculopapular eruption spread most of the entire body and the presence of facial edema. (B) Clinical course of drug administration and laboratory results during the hospitalization. ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C-reactive protein; iv, intravenous; LDH, lactate dehydrogenase; po, peros (oral); qd, quaque die (daily); WBC, white blood cell.
case_images: fphar-15-1355774-g001.jpg
case_images: PMC10955048_01_fphar-15-1355774-g001.jpg
case_images: F1
case_images: Facial swelling was also found (Figure 1A and Supplementary Figure S1). His blood ferritin level was elevated at 1,223 ng/mL, C-reactive protein was increased at 34.4 mg/L, and procalcitonin level was 1.3 ng/mL (Figure 1B). The skin eruption in the trunk and extremities and facial edema improved remarkably (Supplementary Figure S1), and his WBC count, kidney and liver function returned to normal (Figure 1B).