case_images: PMC5726672_01
case_images: Scattered tense vesicles/bullae on the nasal and labial mucosa
case_images: abd-92-05-s1-0037-g01.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g01.jpg
case_images: f1
case_images: She developed tense, isolated and grouped vesiculobullous lesions on the face, neck, axillae, upper limbs, inguinal region, buttocks and oral, nasal and genital mucosa, over 1 week (Figures 1 to 3). She also had occasional fever and hepatomegaly.
case_images: Involvement of the left inguinal region and vaginal introitus
case_images: abd-92-05-s1-0037-g03.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g03.jpg
case_images: f3
case_images: She developed tense, isolated and grouped vesiculobullous lesions on the face, neck, axillae, upper limbs, inguinal region, buttocks and oral, nasal and genital mucosa, over 1 week (Figures 1 to 3). She also had occasional fever and hepatomegaly.
case_images: Subepidermal blister filled with fibrin, lymphomononuclear and
  neutrophils. Basement membrane thickening (Hematoxylin & eosin,
  X100)
case_images: abd-92-05-s1-0037-g04.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g04.jpg
case_images: f4
case_images: She developed tense, isolated and grouped vesiculobullous lesions on the face, neck, axillae, upper limbs, inguinal region, buttocks and oral, nasal and genital mucosa, over 1 week (Figures 1 to 3). She also had occasional fever and hepatomegaly.
case_images: Direct immunofluorescence with linear deposits of C3 in the BMZ
case_images: abd-92-05-s1-0037-g05.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g05.jpg
case_images: f5
case_images: Histology from skin biopsy revealed subepidermal blister filled with fibrin, lymphomononuclear cells and neutrophils, thickening of the basement membrane in the dermal papillae and mild perivascular lymphoplasmacytic infiltrate in the papillary, superficial dermis (Figure 4).
case_images: Direct immunofluorescence with fluorescence of the keratinocyte
  nuclei
case_images: abd-92-05-s1-0037-g06.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g06.jpg
case_images: f6
case_images: Direct immunofluorescence (DIF) showed deposition of linear IgG, IgA and C3 in the basement membrane zone and granular IgM (Figure 5).
case_images: Tense bullae overlying an erythematous base on the right axilla
case_images: abd-92-05-s1-0037-g02.jpg
case_images: PMC5726672_01_abd-92-05-s1-0037-g02.jpg
case_images: f2
case_images: IgG in the dermis and epidermis and for IgA in the epidermis. Indirect immunofluorescence was negative for IgA, IgM and IgG, but the nuclei of keratinocytes fluoresced (Figure 6).