case_images: PMC4617320_01
case_images: MRI findings.. (
  1-A) - Axial MRI FLAIR image from the affected female child done at 4.5 years of age shows hyperintensities in the periventricular (primarily periatrial) white matter (arrows). (
  1-B) Axial FLAIR and sagittal T1 MRI images from the affected male child at 2.5 years of age. This shows bilateral periventricular (periatrial) and subcortical white matter hyperintensities consistent with dysmyelination (arrows). Brain architecture (corpus callosum, cerebellum, and cortical gyration) was normal.
case_images: f1000research-4-7652-g0000.jpg
case_images: PMC4617320_02_f1000research-4-7652-g0000.jpg
case_images: f1
case_images: MRI of the brain at age 2.5 years showed extensive FLAIR/T2 hyperintensities in the periventricular and subcortical white matter ( Figure 1B).
case_images: PMC4617320_02
case_images: MRI findings.. (
  1-A) - Axial MRI FLAIR image from the affected female child done at 4.5 years of age shows hyperintensities in the periventricular (primarily periatrial) white matter (arrows). (
  1-B) Axial FLAIR and sagittal T1 MRI images from the affected male child at 2.5 years of age. This shows bilateral periventricular (periatrial) and subcortical white matter hyperintensities consistent with dysmyelination (arrows). Brain architecture (corpus callosum, cerebellum, and cortical gyration) was normal.
case_images: f1000research-4-7652-g0000.jpg
case_images: PMC4617320_02_f1000research-4-7652-g0000.jpg
case_images: f1
case_images: MRI of the brain at age 2.5 years showed extensive FLAIR/T2 hyperintensities in the periventricular and subcortical white matter ( Figure 1B).