case_images: PMC11292613_01
case_images: PMC11292613_02
case_images: PMC11292613_03
case_images: PMC11292613_04
case_images: Green triangles represent the indocyanine green injection sites for each case on both the front and back of their body. Near-infrared fluorescence lymphatic imaging (NIRFLI) was obtained for up to 3 h. The first hour captured lymphatic flow immediately before treatment with the automated manual lymphatic drainage mat. The second hour captured lymphatic flow while each patient underwent 1-hour of concurrent pneumatic compression therapy (PCT) with the automated manual lymphatic drainage mat. The final 30 to 60 min captured posttreatment lymphatic flow. The injection protocol for Case 1, a 58-year-old male patient with complex regional pain syndrome and stage 1 lymphedema (LE) in his right foot and calf is depicted in 1A. The protocol for Case 2, a 52-year-old, healthy male patient with no relevant history of LE is shown in 1B. The protocol for Case 3, a 71-year-old breast cancer survivor with chronic pain from rheumatoid arthritis and degenerative joint disease and a history of LE is shown in 1C. The protocol for Case 4, a 64-year old female patient with a history of abdominoplasty and brachioplasty that caused prior LE is shown in 1D.
case_images: fmedt-06-1397561-g001.jpg
case_images: PMC11292613_04_fmedt-06-1397561-g001.jpg
case_images: F1
case_images: The final concentration of 0.32 mM provided 25 mug ICG/injection, with each injection of 0.1 cc made at the anatomical injection sites shown in Figure 1.