case_images: PMC3460900_01
case_images: Schematic diagram of two-step mapping strategy.. The genotyping was first conducted with 10 STR markers covering a 30-Mb region on 4q31-q32 and followed by 80 SNPs spanning the region from D4S1498 to D4S413. Lastly, the minimal UPD region was estimated to be from rs17035464 to D4S1498 in a physical distance of 14 Kb.
case_images: pone.0046477.g003.jpg
case_images: PMC3460900_01_pone.0046477.g003.jpg
case_images: pone-0046477-g003
case_images: Proband 152 was a 1-year-old girl with bilateral cleft lip and palate, and no other noticeable abnormalities were found after a comprehensive postnatal physical examination (Figure 3).