case_images: PMC10626150_01
case_images: (A-B) Contrast-enhanced CT showing heterogeneously enhancing mass adjacent to the transverse colon and right lower pole kidney mass.
case_images: JKCVHL-10-007-g001.jpg
case_images: PMC10626150_01_JKCVHL-10-007-g001.jpg
case_images: F1
case_images: Contrast-enhanced computed tomography (CT) of the abdomen showed a 20 cm heterogeneously enhancing mass adjacent to the transverse colon (Figure 1A, 1B). A 2.5 cm enhancing mass was also noted in the lower pole of the right kidney (Figure 1A, 1B).
case_images: (A) Intraoperative image showing large mass adjacent to transverse colon. (B) Resected specimen of transverse colon mass. (C) Resected specimen of right renal mass.
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case_images: PMC10626150_01_JKCVHL-10-007-g002.jpg
case_images: F2
case_images: Figure 2A-C shows intraoperative image of the mass and resected specimen.
case_images: (A) Renal tumor showing glands lined by tumor cells with clear cytoplasm, well defined cell borders, and vesicular nuclei with small nucleoli. H&E 200x. (B) Spindle-shaped tumor cells show abundant cytoplasm with vesicular to hyperchromatic nuclei with prominent nucleoli and increased mitosis. H&E 200x. (C) Tumor cells with rhabdoid morphology shows hyperchromatic, pleomorphic nuclei with prominent nucleoli. H&E 200x.
case_images: JKCVHL-10-007-g003.jpg
case_images: PMC10626150_01_JKCVHL-10-007-g003.jpg
case_images: F3
case_images: Final pathology of the right renal mass confirmed clear-cell RCC (Figure 3A). The large mass showed neoplasm composed of cells arranged in sheets, with abundant cytoplasm with vesicular to hyperchromatic nuclei with prominent nucleoli (Figure 3B). Sarcomatoid and rhabdoid features were noted with areas of necrosis (Figure 3C).
case_images: (A) Tumor cells express CD 10. DAB 200x. (B) Tumor cells express Carbonic Anhydrase 9. DAB 200x. (C) Tumor cells express vimentin. DAB 200x.
case_images: JKCVHL-10-007-g004.jpg
case_images: PMC10626150_01_JKCVHL-10-007-g004.jpg
case_images: F4
case_images: Immunohistochemistry profile, positive for CD 10 (Figure 4A), Carbonic Anhydrase 9 (Figure 4B), Vimentin (Figure 4C), and Keratin, confirmed metastasis from the renal tumor.