case_images: PMC11004351_01
case_images: PMC11004351_02
case_images: (A) The patient's interictal period EEG. (B) The patient's ictal period EEG. (C-F) The patient's MRI before coagulation. (G) Whole-exome sequencing of monogenic disease.
case_images: fneur-15-1366776-g001.jpg
case_images: PMC11004351_04_fneur-15-1366776-g001.jpg
case_images: fig1
case_images: EEG showed slow spike-wave discharges originated from bilateral temporal lobes (Figure 1A). EEG registered three times seizures during the ictal period, including once focal impaired awareness behavior arrest seizure and twice focal to bilateral tonic-clonic seizures. During the ictal period, EEG registered the epileptiform discharges originating from the left temporal-occipital junction and gradually generalized to the bilateral cerebral hemispheres (Figure 1B).
case_images: PMC11004351_03
case_images: PMC11004351_04
case_images: (A) The patient's interictal period EEG. (B) The patient's ictal period EEG. (C-F) The patient's MRI before coagulation. (G) Whole-exome sequencing of monogenic disease.
case_images: fneur-15-1366776-g001.jpg
case_images: PMC11004351_04_fneur-15-1366776-g001.jpg
case_images: fig1
case_images: EEG showed slow spike-wave discharges originated from bilateral temporal lobes (Figure 1A). EEG registered three times seizures during the ictal period, including once focal impaired awareness behavior arrest seizure and twice focal to bilateral tonic-clonic seizures. During the ictal period, EEG registered the epileptiform discharges originating from the left temporal-occipital junction and gradually generalized to the bilateral cerebral hemispheres (Figure 1B).
case_images: The patient's interictal period SEEG before coagulation. (A) Left electrodes (m/n: occipital lobe-occipital horn nodes; h/i: temporal-occipital junction-occipital horn nodes). (B) Right electrodes (KK/M: temporal-occipital junction-occipital horn nodes; N: superior temporal gyrus-atrial nodes; I: middle temporal gyrus posterior-temporal horn nodes).
case_images: fneur-15-1366776-g002.jpg
case_images: PMC11004351_04_fneur-15-1366776-g002.jpg
case_images: fig2
case_images: SEEG registered epileptiform discharges mainly originated from heterotopic nodes in the left occipital lobe, temporal-occipital junctions (both left and right), right superior temporal gyrus, and the middle temporal gyrus posterior during the interictal period (Figures 2A,B).
case_images: The patient's ictal period SEEG before coagulation. (A) Left electrodes (m/n: occipital lobe-occipital horn nodes; h/i: temporal-occipital junction-occipital horn nodes; k: middle temporal gyrus-atrial nodes; e/d/b: middle temporal gyrus-temporal horn nodes). (B) Right electrodes (KK/M: temporal-occipital junction-occipital horn nodes; N: superior temporal gyrus-atrial nodes; I: middle temporal gyrus posterior-temporal horn nodes; H/B: middle temporal gyrus-temporal horn nodes).
case_images: fneur-15-1366776-g003.jpg
case_images: PMC11004351_04_fneur-15-1366776-g003.jpg
case_images: fig3
case_images: Ictal onset was registered from the left temporal-occipital junction heterotopic nodes on SEEG (leads h7-h12; Figures 3A,B).
case_images: PMC11004351_05
case_images: (A-D) The patient's MRI 2 months after coagulation. (E,F) The patient's interictal period EEG 2 months after coagulation.
case_images: fneur-15-1366776-g004.jpg
case_images: PMC11004351_05_fneur-15-1366776-g004.jpg
case_images: fig4
case_images: Follow-up after coagulation (Figures 4A-F): at the 2 months after coagulation, EEG registered occasional epileptiform discharges in bilateral temporal lobes during the interictal period.