case_images: PMC11144427_01
case_images: Hb-electrophoresis chromatogram of Case 1 shows the presence of the Hb variant suggestive of Hb S and Hb E with their percentage.
case_images: JBM-15-255-g0002.jpg
case_images: PMC11144427_01_JBM-15-255-g0002.jpg
case_images: f0001
case_images: Hb S/Hb E was suggested from CE (Figure 1).
case_images: PMC11144427_02
case_images: Continued.
case_images: JBM-15-255-g0003.jpg
case_images: PMC11144427_02_JBM-15-255-g0003.jpg
case_images: f0002a
case_images: A2 that is suggestive of Hb E (Figure 2A and B). His mother is heterozygous Hb G-Makassar. Automated HPLC showed a peak at S-window suggestive of Hb S, but DNA analysis confirmed the diagnosis of heterozygous Hb G-Makassar (Figure 2C).
case_images: PMC11144427_03
case_images: Continued.
case_images: JBM-15-255-g0004.jpg
case_images: PMC11144427_03_JBM-15-255-g0004.jpg
case_images: f0002b
case_images: As shown in Figure 3, Hb G-Makassar level was high within this cohort with a mean of 66.6% +- 3.7.