case_images: PMC5842716_01
case_images: Family pedigree. Standard pedigree symbols are used. An arrow indicates the proband. The numbers inside the symbols represent the number of family members. The numbers at the right lower side of the symbols represent current age or age at death of the individuals. Asterisks indicate individuals that underwent whole exome sequencing.
case_images: CRIG2018-6968395.001.jpg
case_images: PMC5842716_01_CRIG2018-6968395.001.jpg
case_images: fig1
case_images: Upon ascertainment of family history, we found that one of the proband's sisters and his daughter both shared his symptoms of hives and angioedema (Figure 1).