case_images: PMC3806683_01
case_images: Findings in a 39-year-old woman with AZOOR in the right (a-e) and left (f-j) eyes. Fundus photographs show no specific abnormalities (a, f). OCT horizontal scan (b) and high-magnification OCT findings (c) show an absent photoreceptor IS/OS line and the COST line within AZOOR lesions (in the macula area) in the right eye. In the left eye, the IS/OS line and the COST line were detected (g, h). mfERG response arrays (d, i) and 3-dimensional plots (e, j) showed reduced responses in the right eye. Arrowheads indicate the IS/OS line. Arrows indicate the COST line.
case_images: cop-0004-0099-g01.jpg
case_images: PMC3806683_01_cop-0004-0099-g01.jpg
case_images: F1
case_images: No inflammatory cells were observed in the anterior segment or vitreous of either eye, and there were no specific abnormal findings during a fundus examination (fig. 1a, f). OCT (RS-3000; Nidek, Japan) showed that while there was attenuation of the IS/OS line throughout the entire region of her right eye and the COST line (fig. 1b, c), no specific abnormalities were detected in her left eye (fig. 1g, h). mfERG (LE-4100; Tomey, Japan) findings showed markedly decreased amplitudes in the right eye (fig. 1d, e) and no abnormalities in the left eye (fig. 1i, j). The patient was followed without any treatment.
case_images: Changes in high-magnification OCT findings in a 39-year-old woman with AZOOR in the right eye (a-c). At the initial visit, OCT showed attenuation of the IS/OS line and the COST line (a). After 2 months, OCT showed a partial restoration of the IS/OS line (b); however, the COST line was still absent. At 4 months, reappearance of the IS/OS line was detected by OCT (c); however, the COST line was still absent. Arrowheads indicate the IS/OS line.
case_images: cop-0004-0099-g02.jpg
case_images: PMC3806683_01_cop-0004-0099-g02.jpg
case_images: F2
case_images: BCVA improved to 0.9 in the right eye and OCT revealed there was no recovery of the IS/OS at the foveal area at 1 month after the initial visit (fig. 2a). After 2 months, BCVA improved to 1.2 in the right eye and OCT showed a partial restoration of the IS/OS line (fig. 2b); however, the COST line was still absent, and she had no change in mfERG findings. At 4 months, reappearance of the IS/OS line was detected by OCT (fig. 2c).