case_images: PMC11418628_01
case_images: (a) Fluorodeoxyglucose hyperaccumulation in the right neck (SUVmax = 9.29). (b) FDG hyperaccumulation in the duodenum (SUVmax = 4.92).
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case_images: Three months ago, a follow-up fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) indicated FDG accumulation in the hypopharynx (Figure 1a), duodenum (Figure 1b), liver, and gluteus medius muscle.
case_images: (a) White light imaging. A red protruding tumor located in the pisiform fossa. (b) White light imaging. A lesion of recurrent renal cell carcinoma bumping from the duodenal wall near the papilla of Vater.
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case_images: The patient was diagnosed with squamous cell carcinoma cT2N0M0 of the hypopharynx (Figure 2a) and recurrent RCC of the duodenum (Figure 2b), liver, and gluteus medius muscle, according to hypopharyngeal and liver biopsy.
case_images: The resected lesion (squamous cell carcinoma, 35 x 32 mm, 0-Is+IIb, tumor thickness 4000 microm, Ly0, V1, pHMx, and pVM0).
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case_images: ESD revealed squamous cell carcinoma of 35 x 32 mm, subclassification for superficial cancers of 0-Is + IIb, tumor thickness of 4000 microm, lymphatic invasion of Ly0, venous invasion of V1, proximal margin of pHMx, and vertical margin of pVM0 (Figure 3).
case_images: (a) Hypopharyngeal cancer in the pisiform fossa completely resected by endoscopic submucosal dissection. Signs of local recurrence were not noted. (b) The duodenal lesion of recurrent renal cell carcinoma disappeared after the completion of immunotherapy with ipilimumab and nivolumab.
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case_images: The patient was regularly followed up by CT and upper gastrointestinal endoscopy (Figure 4a,b) for 3 years, revealing no obvious recurrence of both hypopharyngeal cancer and RCC.