case_images: PMC11721699_01
case_images: Clinical manifestations (A): multiple hyperkeratotic, skin-colored, flat-topped papules localized to the perivulvar region and bilateral inner thighs; Histopathological findings (B): hyperkeratosis, hypergranulosis, and papillomatous epidermal hyperplasia with focal acantholytic dyskeratosis in the epidermis (hematoxylin-eosin, original magnification x40; inset demonstrating high-power view).
case_images: CCID-18-31-g0001.jpg
case_images: PMC11721699_01_CCID-18-31-g0001.jpg
case_images: f0001
case_images: Physical examination revealed multiple hyperkeratotic, skin-colored, flat-topped papules localized to the perivulvar region and bilateral inner thighs (Figure 1A). Histopathological analysis demonstrated hyperkeratosis, hypergranulosis, and papillomatous epidermal hyperplasia with focal acantholytic dyskeratosis in the epidermis (Figure 1B).