case_images: PMC10556250_01
case_images: (A) The macroscopic appearance of the surgically resected lesion (a smooth flattened tumour of a whitish colour and solid consistency), (B-E) microscopic views of slides in haematoxylin-eosin staining. Microscopically, cross-sections of the lung tissue with a defined nodular focus produced by an amorphous eosinophilic matrix (typical for the morphology of the amyloid deposits). Black arrow-the main part of the amyloidoma mass (with numerous calcifications), green arrow-residual lung tissue.
case_images: pore-29-1611390-g002.jpg
case_images: PMC10556250_01_pore-29-1611390-g002.jpg
case_images: F2
case_images: Cross-sections of the lung tissue with a demarcated nodular focus formed by an amorphous eosinophilic matrix, consistent with the amyloid appearance, were observed microscopically (Figure 2).
case_images: A summary of the special staining techniques used during the histopathological evaluation. (A) CD68 (with visible B-lymphocytes of plasmacytoid differentiation), (B) CD138 (from the same specimen area as the previous one), (C) kappa light chains, (D) lambda light chains, (E-H) Congo red [(E,F) light microscopy; (G,H) polarised light imaging with typical apple green dichroism].
case_images: pore-29-1611390-g003.jpg
case_images: PMC10556250_01_pore-29-1611390-g003.jpg
case_images: F3
case_images: Selective immunohistochemical staining was used to detect lambda and kappa immunoglobulin light chains, but only polytypic expression was observed (i.e., no restriction; Figure 3).