case_images: PMC10625818_01
case_images: At baseline visit, the patient presented white-yellowish thick scales, easily detachable from both the upper and lower lips.
case_images: cde-2023-0015-0001-532103_F01.jpg
case_images: PMC10625818_01_cde-2023-0015-0001-532103_F01.jpg
case_images: F1
case_images: Physical examination revealed the presence of white-yellowish thick scales, easily detachable from both the upper and lower lips, revealing an erythematous background and fissuring (shown in Fig. 1).
case_images: Histological sections of lip biopsy (stained with hematoxylin and eosin [H&E]) under x4 (a) and x20 (b) magnifications. Histological examination showed epidermal acanthosis with elongated rete ridges and a mild lymphocytic infiltrate in the superficial dermis.
case_images: cde-2023-0015-0001-532103_F02.jpg
case_images: PMC10625818_01_cde-2023-0015-0001-532103_F02.jpg
case_images: F2
case_images: Histological examination revealed epidermal acanthosis with elongated rete ridges, and a mild lymphocytic infiltrate in the superficial dermis (shown in Fig. 2).
case_images: a After 2 months of therapy. b After 6 months of therapy.
case_images: cde-2023-0015-0001-532103_F03.jpg
case_images: PMC10625818_01_cde-2023-0015-0001-532103_F03.jpg
case_images: F3
case_images: After 2 months of therapy, the patient presented significant improvement in his clinical condition, showing good resolution of scaling lesions (shown in Fig. 3a). Only mild lip xerosis remained, which was treated with a topical emollient (shown in Fig. 3b).