case_images: PMC11740298_01
case_images: Protocol of the treatments and examination of the microorganisms associated with phage treatment. This diagram presents the treatments and examination of microorganisms over time in this patient. Results of microorganism examinations are shown as different colours. This patient underwent three types of treatment: 1. Antifungal treatment: Voriconazole (150 mg, q12 h); 2. Antibiotics treatments: Clindamycin (0.6 g, q12 h), Cefuroxime (1.5 g, q12 h), Levofloxacin (0.5 g, q.d.), Amikacin/Tazocin (0.8 g/4.5 g, q.d./q8 h), Amikacin/Meropenem (0.4 g/1 g, q8 h); 3. Phage therapy (109 PFU/mL, q12 h).
case_images: TEMI_A_2451048_F0001_PC.jpg
case_images: PMC11740298_01_TEMI_A_2451048_F0001_PC.jpg
case_images: F0001
case_images: S. marcescens infection was not ameliorated (Figure S1). Subsequent antibiotic susceptibility tests revealed intrinsic resistance of S. marcescens isolates to polymyxin B, ampicillin, and various cephalosporin antibiotics. Fungal cultures were negative after a 137-day treatment with voriconazole (Figure 1).