case_images: PMC3362992_01
case_images: Perianal plaques in various stages of eruption.
case_images: CRIM.ID2012-948530.001.jpg
case_images: PMC3362992_01_CRIM.ID2012-948530.001.jpg
case_images: fig1
case_images: The lesions began eight weeks prior to presentation, were multiple, scattered in the perianal area and upper thigh bilaterally, and three centimeters at the widest diameter (Figure 1).
case_images: Skin biopsy with hematoxylin/eosin at 400x power. Lymphocytic infiltrate of dermis with enlarged endothelial cells and occasional magenta-colored intranuclear inclusions.
case_images: CRIM.ID2012-948530.002.jpg
case_images: PMC3362992_01_CRIM.ID2012-948530.002.jpg
case_images: fig2
case_images: However, the superficial dermis demonstrated a distinct perivascular lymphocytic infiltrate, and the endothelial cells were markedly enlarged (Figure 2).
case_images: Skin biopsy with immunoperoxidase stain at 400x power. Cytomegalovirus positive cell featured in the center of view.
case_images: CRIM.ID2012-948530.003.jpg
case_images: PMC3362992_01_CRIM.ID2012-948530.003.jpg
case_images: fig3
case_images: Some endothelial cells contained magenta-colored nuclear inclusions consistent with cytomegalovirus (CMV) infection which was confirmed by a positive CMV immunostain (Figure 3).