case_images: PMC5824516_01
case_images: H & E stain of 10X view showing tumour cells arranged in alveolar pattern separated by fibrovascular stroma
case_images: JOMFP-22-44-g001.jpg
case_images: PMC5824516_01_JOMFP-22-44-g001.jpg
case_images: F1
case_images: On microscopic examination, the tumor was composed of cells arranged in alveolar pattern separated by fibrovascular stroma [Figure 1].
case_images: H & E stain 40x view showing Two distinctive types of cells - large cells arranged peripherally with abundant cytoplasm, round vesicular nucleus and brown pigment; and small cells with scanty cytoplasm and hyperchromatic round nuclei were seen in the center
case_images: JOMFP-22-44-g002.jpg
case_images: PMC5824516_01_JOMFP-22-44-g002.jpg
case_images: F2
case_images: Two distinctive types of cells were seen - large cells arranged peripherally with abundant cytoplasm, round vesicular nucleus and brown pigment; and small cells with scanty cytoplasm and hyperchromatic round nuclei were seen in the center [Figure 2].
case_images: IHC Stain Cytokeratin
case_images: JOMFP-22-44-g003.jpg
case_images: PMC5824516_01_JOMFP-22-44-g003.jpg
case_images: F3
case_images: Cytokeratin, [Figure 3] MELAN-A and HMB45 [Figure 4] were positive in large cells and negative for small cells.
case_images: IHC stain HMB45
case_images: JOMFP-22-44-g004.jpg
case_images: PMC5824516_01_JOMFP-22-44-g004.jpg
case_images: F4
case_images: Cytokeratin, [Figure 3] MELAN-A and HMB45 [Figure 4] were positive in large cells and negative for small cells.
case_images: IHC Stain NSE
case_images: JOMFP-22-44-g005.jpg
case_images: PMC5824516_01_JOMFP-22-44-g005.jpg
case_images: F5
case_images: Neuron-specific enolase (NSE) [Figure 5] and synaptophysin [Figure 6] were positive in small round cells and negative in large cells.
case_images: IHC Stain Synaptophysin
case_images: JOMFP-22-44-g006.jpg
case_images: PMC5824516_01_JOMFP-22-44-g006.jpg
case_images: F6
case_images: Neuron-specific enolase (NSE) [Figure 5] and synaptophysin [Figure 6] were positive in small round cells and negative in large cells.