case_images: PMC10081667_01
case_images: Chest computed tomography (CT) in the axial plane showing pneumomediastinum outlining the heart and other mediastinal structures. The lung parenchyma shows multiple bilateral peripheral and subpleural areas of ground-glass opacities.
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case_images: When her symptoms exacerbated, CT chest was repeated, and there was a considerable progression of the pneumomediastinum, with an extension of the air to the subcutaneous tissue causing subcutaneous emphysema (Figure 1).
case_images: Axial chest CT with contrast showing the progression of the pneumomediastinum with air pockets in the left para-mediastinal region and subcutaneous emphysema.
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case_images: In addition, the pneumomediastinum seemed to have extended to the lower neck and the left para-mediastinal region; there was extensive subcutaneous emphysema (Figures 2 and 3).  
case_images: Coronal CT of the chest with contrast showing extensive pneumomediastinum and subcutaneous emphysema.
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case_images: In addition, the pneumomediastinum seemed to have extended to the lower neck and the left para-mediastinal region; there was extensive subcutaneous emphysema (Figures 2 and 3).  
case_images: PMC10081667_02
case_images: Axial CT of the upper chest with contrast for the second patient, showing pneumomediastinum, along with bilateral subcutaneous emphysema, more predominant on the right side.
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case_images: A follow-up CT chest one month later showed pneumomediastinum along with minimal bilateral pneumothorax (Figure 4). 