case_images: PMC3556306_01
case_images: Massive shallow ulcers on the left inner thigh surrounded by reddish, infiltrated steak.
case_images: 1471-2369-14-20-1.jpg
case_images: PMC3556306_01_1471-2369-14-20-1.jpg
case_images: F1
case_images: A 34-year-old man was admitted to our hospital presented with massive shallow ulcers of both lower extremities (Figure 1), fever of 39 C and severe pain.
case_images: Light microscopic histological findings of the skin biopsy specimen from the cutaneous lesion showed an inflammatory infiltration containing PAS positive micro-organisms. (Periodic acid-Schiff stain; original magnification: x400).
case_images: 1471-2369-14-20-2.jpg
case_images: PMC3556306_01_1471-2369-14-20-2.jpg
case_images: F2
case_images: In the end, investigations on the biopsy revealed the existence of C. neoformans after four days of admission (Figure 2) and the capsular polysaccharide antigen titer of C. neoformans in blood determined by latex particle agglutination method was 1:1024.