case_images: PMC11749575_01
case_images: A 15-year-old male with COVID-19 infection shows low-density shadows (arrow) in the fundus after 3 days. Right eye fundus photograph (A), left eye fundus photograph (B), right eye fundus without red-free (C), left eye fundus without red-free (D). COVID-19 = coronavirus disease 2019.
case_images: medi-104-e41076-g001.jpg
case_images: PMC11749575_01_medi-104-e41076-g001.jpg
case_images: F1
case_images: Oculus Dexter (OD; right eye) 0.8 Oculus Sinister (OS; left eye) 0.8, no improvement in corrected visual acuity, Heidelberg Retina Angiography examination, both color photograph, and the red-free photograph showed triangular neural epithelial edema below the nasal side in the fovea of both eyes, with the tip of the triangle facing towards the central foveal depression (Fig. 1). Optical coherence tomography (OCT) examination revealed high-density shadows in the form of blocks between the neural epithelial and pigment epithelial layers in the foveal area, without obvious interstitial effusion (Fig. 2).
case_images: A 15-year-old male with COVID-19 infection shows high-density shadows (arrow) in OCT after 3 days. Right eye enfaces retina surface (A), left eye enface retina surface (B), right eye OCT fovea (C), left eye OCT fovea (D). COVID-19 = coronavirus disease 2019, OCT = optical coherence tomography.
case_images: medi-104-e41076-g002.jpg
case_images: PMC11749575_01_medi-104-e41076-g002.jpg
case_images: F2
case_images: Oculus Dexter (OD; right eye) 0.8 Oculus Sinister (OS; left eye) 0.8, no improvement in corrected visual acuity, Heidelberg Retina Angiography examination, both color photograph, and the red-free photograph showed triangular neural epithelial edema below the nasal side in the fovea of both eyes, with the tip of the triangle facing towards the central foveal depression (Fig. 1). Optical coherence tomography (OCT) examination revealed high-density shadows in the form of blocks between the neural epithelial and pigment epithelial layers in the foveal area, without obvious interstitial effusion (Fig. 2).
case_images: A 15-year-old male with hormone treatment shows a missing ellipsoid zone (arrow) in OCT after 5 days. Right eye enfaces IS/OS-ellipsoid layer (A), left eye enface IS/OS-ellipsoid layer (B), right eye OCT fovea (C), left eye OCT fovea (D). IS/OS = inner segment/outer segment layer, OCT = optical coherence tomography.
case_images: medi-104-e41076-g003.jpg
case_images: PMC11749575_01_medi-104-e41076-g003.jpg
case_images: F3
case_images: The enface scan showed a low-density shadow in a small area of the ellipsoid band in the macular area (Fig. 3).
case_images: PMC11749575_02
case_images: A 28-year-old female with COVID-19 infection shows low-density shadows (arrow) in the fundus after 10 days. Right eye fundus photograph (A), left eye fundus photograph (B), right eye fundus without red-free (C), left eye fundus without red-free (D). COVID-19 = coronavirus disease 2019.
case_images: medi-104-e41076-g004.jpg
case_images: PMC11749575_02_medi-104-e41076-g004.jpg
case_images: F4
case_images: OD 0.4 and OS 0.3, with no improvement after correction, wide-angle fundus photography showed large central shadows in both eyes and decreased background reflection (Fig. 4). OCT showed large oval lesions in the macula area in both eyes.
case_images: A 28-year-old female with COVID-19 infection shows a missing ellipsoid zone (arrow) in OCT after 10 days. Right eye enfaces IS/OS-ellipsoid layer (A), left eye enface IS/OS-ellipsoid layer (B), right eye OCT fovea (C), left eye OCT fovea (D). COVID-19 = coronavirus disease 2019, IS/OS = inner segment/outer segment layer, OCT = optical coherence tomography
case_images: medi-104-e41076-g005.jpg
case_images: PMC11749575_02_medi-104-e41076-g005.jpg
case_images: F5
case_images: The enface scan showed large oval lesions in the macula area (Fig. 5).