case_images: PMC7339073_01
case_images: A 55-year-old man with nodules of Kaposi sarcoma (KS) in the skin of the medial aspect
  of the right thigh. Purple, raised skin nodules (arrows) are present in the skin of the
  inner aspect of the right thigh, consistent with Kaposi sarcoma (KS).
case_images: 10.1177_2050313X20938249-fig1.jpg
case_images: PMC7339073_01_10.1177_2050313X20938249-fig1.jpg
case_images: fig1-2050313X20938249
case_images: Examination of the skin showed a cluster of dark nodular lesions on his medial right thigh and purple plaques of varying size below the knees (Figures 1 and 2).
case_images: A 55-year-old man with purple, raised nodules of Kaposi sarcoma (KS) in the skin of the
  right lower extremity.
case_images: 10.1177_2050313X20938249-fig2.jpg
case_images: PMC7339073_01_10.1177_2050313X20938249-fig2.jpg
case_images: fig2-2050313X20938249
case_images: Examination of the skin showed a cluster of dark nodular lesions on his medial right thigh and purple plaques of varying size below the knees (Figures 1 and 2).
case_images: A 55-year-old man with violaceous areas of Kaposi sarcoma (KS) in the mucosa of the
  soft palate (arrow).
case_images: 10.1177_2050313X20938249-fig3.jpg
case_images: PMC7339073_01_10.1177_2050313X20938249-fig3.jpg
case_images: fig3-2050313X20938249
case_images: A violaceous lesion was found on examination of the soft palate (Figure 3).
case_images: Photomicrographs of the histology and immunohistochemistry of Kaposi sarcoma (KS) in
  the soft palate biopsy showing: (a) low power view of nodular skin lesion with atypical
  spindle cell proliferation (H&E, 40x), (b) atypical spindle cell proliferation with
  extravasation (100x), and (c) positive immunostaining with an antibody to human
  herpesvirus-8 (HHV-8)-positive for spindle cells (100x).
case_images: 10.1177_2050313X20938249-fig4.jpg
case_images: PMC7339073_01_10.1177_2050313X20938249-fig4.jpg
case_images: fig4-2050313X20938249
case_images: Histopathology showed spindle cells forming slit-like spaces, some of which contained red blood cells (Figure 4(a) and (b)), which supported the diagnosis of KS and excluded some of the possible differential diagnoses, including bacillary angiomatosis, benign hemangioma, and angiosarcoma. Routine diagnostic immunohistochemistry confirmed the presence of HHV-8 (Figure 4(c)), and there was positive immunostaining of the spindle cell populations for the endothelial cell marker CD34.