case_images: PMC11788361_01
case_images: (A) X-ray of the right knee joint revealed a rounded, expansive bony destruction of the right fibular head, measuring (23mmx27mm). (B, C) CT scan and MRI revealed bony destruction of the right fibular head accompanied by a posterior soft tissue mass, measuring (16mmx24mm), suggestive of a neoplastic lesion. CT, computed tomography; MRI, magnetic resonance imaging.
case_images: fonc-15-1490271-g001.jpg
case_images: PMC11788361_01_fonc-15-1490271-g001.jpg
case_images: f1
case_images: X-ray of the right knee joint revealed a rounded expansive bony destruction of the right fibular head ( Figure 1A ), CT scan ( Figure 1B ), and MRI ( Figure 1C ) of the right knee joint depicted bony destruction of the right fibular head accompanied by a posterior soft tissue mass, suggestive of a neoplastic lesion.
case_images: (A) Contrast-enhanced CT scan revealed an irregular mass measuring (28mmx26mmx23mm) in the posterior apical segment of the left upper lobe of the lung. CT, computed tomography. (B) CT-guided puncture and pathologic biopsy of the right lung nodule suggested primary adenocarcinoma of the left lung. CT, computed tomography. (C) CT-guided puncture and pathologic biopsy of the right fibular head mass suggested metastatic adenocarcinoma of the right fibula, possibly originating from the lung. CT, computed tomography.
case_images: fonc-15-1490271-g002.jpg
case_images: PMC11788361_01_fonc-15-1490271-g002.jpg
case_images: f2
case_images: Pathologic biopsy and immunohistochemistry of the right lung nodule and right fibular head mass suggested primary adenocarcinoma of the left lung and metastatic adenocarcinoma of the right fibula, possibly originating from the lung ( Figures 2B, C ).
case_images: (A) Contrast-enhanced CT after Osimertinib therapy revealed a reduction in the size of the lung nodule, measuring (18mmx13mmx9mm). CT, computed tomography. (B, C) Post-radiotherapy follow-up X-ray and MRI indicated a decrease in the size of the fibular metastasis lesion, measuring (15mmx17mm). MRI, magnetic resonance imaging.
case_images: fonc-15-1490271-g003.jpg
case_images: PMC11788361_01_fonc-15-1490271-g003.jpg
case_images: f3
case_images: Chest CT on June 12th, 2022, revealed a reduction in size of the lung nodule, measuring (18mmX13mmX9mm) ( Figure 3A ), the metabolic activity of the lung cancer (SUVmax2.4) and the lesion at the right fibular head (SUVmax2.6) exhibited significant reduction on PET/CT imaging compared to the previous examination. Follow-up examinations post-radiotherapy, including X-ray and MRI, indicated a decrease in the size of the lesion, measuring (15mmx17mm) ( Figures 3B, C ), with the patient experiencing complete pain relief.