case_images: PMC9114733_01
case_images: HPLC chromatogram of HbA1c. Abnormal peak marked by arrow.
case_images: fendo-13-878680-g001.jpg
case_images: PMC9114733_01_fendo-13-878680-g001.jpg
case_images: f1
case_images: The chromatogram showed an abnormal peak between A1c and A0 ( Figure 1 ).
case_images: Chromatography of hemoglobin electrophoresis.
case_images: fendo-13-878680-g002.jpg
case_images: PMC9114733_01_fendo-13-878680-g002.jpg
case_images: f2
case_images: Hemoglobin electrophoresis indicated that hemoglobin A accounted for 45.4% (normal range 96-97.6), and abnormal hemoglobin beta-chain variants accounted for 52.1% ( Figure 2 ).
case_images: Gene mutation in high-throughput sequencing.
case_images: fendo-13-878680-g003.jpg
case_images: PMC9114733_01_fendo-13-878680-g003.jpg
case_images: f3
case_images: The thalassemia gene test suggested a rare type of beta-thalassemia (gene sequencing HBB: c.170G>A, Hb J-Bangkok (GGC->GAC at codon 56) in a beta heterozygous mutation) ( Figure 3 ), which was not one of the 17 common beta-thalassemia-related gene point mutations in Chinese individuals.