case_images: PMC11272550_01
case_images: Subtrochanteric segmental bone defect of the left femur was temporarily stabilized with an intramedullary custom-made PMMA bone cement-coated rod (A). After removal of the rod, a PMMA spacer with colistin was added for dead space management and the bone stabilized with an angular stable plate (B). The second stage of the Masquelet procedure was performed with an intramedullary nailing and augmentation plate. During bone defect reconstruction phages were applied to the DAC  gel (C,D). The DAC gel loaded with Intesti bacteriophage was finally placed on the silver-coated plate (E). Postoperative X-ray demonstrates the bone defect filled with autograft fibula graft and allogenic cancellous bone (F). After 12 months, sufficient bone healing was confirmed by performing X-ray (G) and computed tomography (H).
case_images: fmed-11-1428432-g001.jpg
case_images: PMC11272550_01_fmed-11-1428432-g001.jpg
case_images: fig1
case_images: The Defensive Antibacterial Coating (DAC , Novagenit, Italy) gel loaded with bacteriophage cocktail was applied onto the plate before wound closure (Figure 1).