case_images: PMC10041991_01
case_images: Chest CT scan at admission (A-C) and 2 months after antituberculosis therapy (D-F).
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case_images: CSF examination showed a prominent elevated protein level (2155 mg/dl; normal: 15-45 mg/dl) and a low glucose level (0.85 mmol/L; normal: 2.22-3.89 mmol/L). Chest CT showed nodules with calcification on the upper right lung, and consolidations in both lower lobes (Figure 1 A, B&C). CT scan showed a remissive state of ventriculomegaly, meningeal enhancement, and hydrocephalus (Figure 2E-H). Chest CT showed that his lung lesions improved (Figure 1D-F).
case_images: Brain MRI and CT scan at admission (A-D) and 2 months after antituberculosis therapy (E-H).
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case_images: Magnetic resonance imaging (MRI) showed ventriculomegaly, meningeal enhancement and hydrocephalus (Figure 2A-D). CT scan showed a remissive state of ventriculomegaly, meningeal enhancement, and hydrocephalus (Figure 2E-H). Chest CT showed that his lung lesions improved (Figure 1D-F).
case_images: Long-tunneled external ventricular drain.
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case_images: The patient underwent an emergency surgery of long-tunneled external ventricular drain (LTEVD) and Ommaya reservoir implantation under general anesthesia to relieve elevated intracranial pressure (Figure 3).
case_images: Concentration of various antituberculosis agents in the plasma and cerebrospinal fluid across time.
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case_images: Pharmacokinetics of antituberculosis drugs in the plasma and CSF is shown in Figure 4.
case_images: Timeline of major clinical events.
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case_images: The timeline depicting major clinical events is shown in Figure 5. Throughout the whole anti-TB treatment phase, we monitored his hepatic function regularly and it turned out normal.