case_images: PMC11302599_01
case_images: Preoperative magnetic resonance: T1-weighted axial section demonstrating severe hydrocephalus.
case_images: SNI-15-259-g001.jpg
case_images: PMC11302599_01_SNI-15-259-g001.jpg
case_images: F1
case_images: The diagnosis of intracranial teratoma in the following case was made by means of complementary magnetic resonance imaging (MRI), which showed an expansive and homogeneous intraventricular lesion, without contrast, isointense to the brain parenchyma, with surrounding calcified material, invading the body and anterior horn of the right lateral ventricle, and extending through the third ventricle to the hypothalamus [Figures 1 and 2].
case_images: Preoperative magnetic resonance: coronal T1-weighted slice showing expansive, homogeneous, and isointense right intraventricular lesion to the brain parenchyma, with surrounding calcified material.
case_images: SNI-15-259-g002.jpg
case_images: PMC11302599_01_SNI-15-259-g002.jpg
case_images: F2
case_images: The diagnosis of intracranial teratoma in the following case was made by means of complementary magnetic resonance imaging (MRI), which showed an expansive and homogeneous intraventricular lesion, without contrast, isointense to the brain parenchyma, with surrounding calcified material, invading the body and anterior horn of the right lateral ventricle, and extending through the third ventricle to the hypothalamus [Figures 1 and 2].
case_images: Postoperative magnetic resonance: coronal T1-weighted section with gadolinium after 18 months of surgery demonstrating complete resection of the lesion.
case_images: SNI-15-259-g003.jpg
case_images: PMC11302599_01_SNI-15-259-g003.jpg
case_images: F3
case_images: The surgical treatment of the case was performed after 6 days of the patient's life by means of a right frontal craniotomy, with total macroscopic resection by transcortical approach, through the right middle frontal gyrus, associated with access through the choroidal fissure that was already dilated by the tumor, allowing access to the third ventricle [Figure 3].
case_images: Microscopic examination. (a) x40 fragments of brain nerve tissue showing neocortex with preserved architecture, with areas of associated reactional pattern gliosis. (b) x100. (c) x400.
case_images: SNI-15-259-g004.jpg
case_images: PMC11302599_01_SNI-15-259-g004.jpg
case_images: F4
case_images: Macroscopic and microscopic analysis of the tumor [Figure 4] revealed fragments of cerebral nervous tissue in the midst of zones of gliosis with a reactive pattern, a lesion with morphological aspects suggestive of mature teratoma.
case_images: Immunohistochemical examination. (a) KI-67 positive, reaching about 8% in hot spots. (b) Glial fibrillary acidic protein (GFAP) is positive in areas of interest. (c) Synaptophysin is positive in areas of neuronal differentiation. (d) Neurofilament is positive in areas of neuronal differentiation. (e) Olig-2 positive in a few cells of interest. (f) Alpha thalassemia/mental retardation X-linked (ATRX) is positive in cells of interest.
case_images: SNI-15-259-g005.jpg
case_images: PMC11302599_01_SNI-15-259-g005.jpg
case_images: F5
case_images: After immunohistochemistry [Figure 5], associated with the morphological picture, they led to the diagnosis of mature teratoma.
case_images: PMC11302599_02