case_images: PMC5036401_01
case_images: (a): Section showing oral mucosa and submucosa filled with dense infiltrate comprising inflammatory cells and sheets of large, polygonal cells. (b): Cells have moderate eosinophilic cytoplasm and reniform nuclei exhibiting grooves.
case_images: GMS-14-11-g-001.jpg
case_images: PMC5036401_01_GMS-14-11-g-001.jpg
case_images: F1
case_images: Extensive sampling of this area revealed an ill-defined nodular lesion beneath the epithelium composed of sheets of large, polygonal cells with moderate eosinophilic cytoplasm and reniform nuclei exhibiting grooves (Figure 1 (Fig. 1)).
case_images: Immunohistochemical staining showing (a) LCA reactivity, (b) S100 reactivity, (c) CD1a reactivity in the large cells. . (d) IHC staining for EMA is negative in these cells.
case_images: GMS-14-11-g-002.jpg
case_images: PMC5036401_01_GMS-14-11-g-002.jpg
case_images: F2
case_images: S100, CD68 and negative for LCA, EMA, cytokeratin (Figure 2 (Fig. 2)).