case_images: PMC11797824_01
case_images: Microphotographs showing (A) focal necrosis (black arrow; 400x); (B) cholestasis (black arrows; 400x); (C) fatty degeneration of hepatocytes (200x); (D) Masson stain positive (4x).
case_images: JCTH-13-173-g001.jpg
case_images: PMC11797824_01_JCTH-13-173-g001.jpg
case_images: JCTH-2024-00304-f1
case_images: No abnormalities were noted in the small bile ducts or small blood vessels, but fibrous tissue hyperplasia was observed, with some extending into the lobules, indicating a fibrosis stage of S1-2 (Fig. 1A-C). Masson staining further confirmed collagen fiber deposition (Fig. 1D).
case_images: First-generation sequencing peak map.. The peak marked with an arrow indicates the homozygous nucleotide variant c.315-48T>C.
case_images: JCTH-13-173-g002.jpg
case_images: PMC11797824_01_JCTH-13-173-g002.jpg
case_images: JCTH-2024-00304-f2
case_images: Verification through both second-generation and first-generation sequencing confirmed the accuracy and reliability of this variation (Fig. 2).
case_images: Liver function test results.. ALT, alanine aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase.
case_images: JCTH-13-173-g003.jpg
case_images: PMC11797824_01_JCTH-13-173-g003.jpg
case_images: JCTH-2024-00304-f3