case_images: PMC6593915_01
case_images: Demonstrating the four generations of affected members of the family pedigree (y: Years).
case_images: NCI-6-176-g001.jpg
case_images: PMC6593915_01_NCI-6-176-g001.jpg
case_images: F1
case_images: The cases were listed by their location in the pedigree (Fig. 1).
case_images: Left eye corneal photograph of Case 1. Opacities of granular corneal dystrophy were seen in the corneal stroma.
case_images: NCI-6-176-g002.jpg
case_images: PMC6593915_01_NCI-6-176-g002.jpg
case_images: F2
case_images: BCVA was 20/20 unaided bilaterally. Bilateral slit lamp biomicroscopy revealed symmetrical, sharply demarcated, non-coalescent, grayish-white opacities only in the stroma layer (Fig. 2).
case_images: (A) Subclinical keratoconus findings in the right eye topograph of Case 1 (mother of the proband). (B) Subclinical keratoconus findings in the left eye topograph of Case 1 (mother of the proband).
case_images: NCI-6-176-g003.jpg
case_images: PMC6593915_01_NCI-6-176-g003.jpg
case_images: F3
case_images: She was diagnosed with bilateral subclinical keratoconus by topographic examination according to Ucakhan et al. (Fig. 3A, Fig. 3B).
case_images: Right eye photograph of the proband (Case 4). Sharply demarcated, grayish-white, non-coalescent, star-shaped opacities localized only to the stroma.
case_images: NCI-6-176-g004.jpg
case_images: PMC6593915_01_NCI-6-176-g004.jpg
case_images: F4
case_images: Corneal ectasia with the presence of Vogt's striae and a Fleischer's ring and sharply demarcated, grayish-white, non-coalescent, star-shaped opacities localized only to the stroma were found bilaterally on biomicroscopic examination (Fig. 4).
case_images: (A) Keratoconus findings in the right eye topograph of the proband (Case 4). (B) Keratoconus findings in the left eye topograph of the proband (Case 4).
case_images: NCI-6-176-g005.jpg
case_images: PMC6593915_01_NCI-6-176-g005.jpg
case_images: F5
case_images: She was diagnosed with bilateral clinical keratoconus by topographic examination (Fig. 5A, Fig. 5B).
case_images: Left eye corneal photograph of Case 7. Opacities of granular corneal dystrophy were seen in the corneal stroma.
case_images: NCI-6-176-g006.jpg
case_images: PMC6593915_01_NCI-6-176-g006.jpg
case_images: F6
case_images: Similar to other cases, bilateral and symmetrical, sharply demarcated, grayish-white, non-coalescent, star-shaped specular mild opacities were seen only in the stroma layer on biomicroscopic examination (Fig. 6).
case_images: (A) Subclinical keratoconus findings in the right eye topograph of Case 7 (daughter of the proband). (B) Subclinical keratoconus findings in the left eye of Case 7 (daughter of the proband).
case_images: NCI-6-176-g007.jpg
case_images: PMC6593915_01_NCI-6-176-g007.jpg
case_images: F7
case_images: She was diagnosed with bilateral subclinical keratoconus by topographic examination (Fig. 7A, Fig. 7B).