case_images: PMC5771900_01
case_images: Imaging findings in case 1. On MRI of the sacral spine, the tumorous lesion has clear margins and is enclosed by the S1 vertebral body. The signal intensities are homogeneously low in T1-weighted images (A) and high in T2-weighted images (B), and no enhancement is observed in T1-weighted images with a gadolinium contrast medium (C). No extraosseous lesion or enlargement is observed. CT image demonstrates slight osteosclerosis throughout the tumorous lesion and no osteolytic changes in the vertebral body (D).
case_images: CCR3-6-63-g001.jpg
case_images: PMC5771900_01_CCR3-6-63-g001.jpg
case_images: ccr31287-fig-0001
case_images: T1-weighted images and high in T2-weighted images, and no enhancement was observed in T1-weighted images with a gadolinium contrast medium. There were no extraosseous lesions or enlargements (Figure 1A-C). There were no osteolytic changes in the vertebral body (Figure 1D).
case_images: An image of CT-guided needle biopsy procedure in case 1. The vertebral tumor has been accessed through the sacroiliac joint to obtain a biopsy specimen.
case_images: CCR3-6-63-g002.jpg
case_images: PMC5771900_01_CCR3-6-63-g002.jpg
case_images: ccr31287-fig-0002
case_images: Because no additional abnormalities were identified on whole-body analysis, a CT-guided needle biopsy of the vertebral tumor was performed (Figure 2).
case_images: Histopathological findings in case 1 (H&E, A x4, B x40). Photomicrographs show proliferation of physaliferous cells without nuclear atypia between thickened bone frameworks. There was no bone destruction and myxoid matrix.
case_images: CCR3-6-63-g003.jpg
case_images: PMC5771900_01_CCR3-6-63-g003.jpg
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case_images: The percentage of cells that were positive for Ki-67 was less than 1% (Figure 3).
case_images: PMC5771900_02
case_images: Imaging findings in case 2. On MRI of the sacral spine, the signal intensities of the tumorous lesion are homogeneously low in T1-weighted images and high in T2-weighted images, and no enhancement is observed in fat-suppression T1-weighted images with a gadolinium contrast medium in the S2 vertebral body (A-C). CT image demonstrates slight osteosclerosis throughout the tumorous lesion and no osteolytic changes (D).
case_images: CCR3-6-63-g004.jpg
case_images: PMC5771900_02_CCR3-6-63-g004.jpg
case_images: ccr31287-fig-0004
case_images: MRI revealed that the signal intensities of the tumorous lesion were homogeneously low in T1-weighted images and high in T2-weighted images, and no enhancement was observed in fat-suppression T1-weighted images with a gadolinium contrast medium (Figure 4A-C). CT of the lesion demonstrated slight osteosclerosis without osteolytic changes (Figure 4D).