case_images: PMC3056220_01
case_images: CT scan of chest demonstrated multicompartmental mediastinal lymphadenopathy, for example, a right paratracheal node measuring 14 mm in short axis.
case_images: JTRAN2011-919651.001.jpg
case_images: PMC3056220_01_JTRAN2011-919651.001.jpg
case_images: fig1
case_images: CT of chest, abdomen, and pelvis revealed numerous lymph nodes in the mediastinum, cervical, and abdominal regions (Figure 1).
case_images: Lymph node architecture has been subtotally replaced by a diffuse proliferation of small, medium, and large lymphoid cells. (a) positive LMP-1 stain, (b) positive CD-20 antibody stain. Immunohistochemical staining with Kappa and Lambda (c and d, resp.) showed many transformed cells and was positive for plasma cells.
case_images: JTRAN2011-919651.002.jpg
case_images: PMC3056220_01_JTRAN2011-919651.002.jpg
case_images: fig2
case_images: Excisional lymph node biopsy of the right scalene lymph node was positive for polymorphic PTLD (Figure 2).
case_images: CT scan of chest posttreatment showed mediastinal nodes decreasing in size.
case_images: JTRAN2011-919651.003.jpg
case_images: PMC3056220_01_JTRAN2011-919651.003.jpg
case_images: fig3
case_images: With the reduction in immunosuppression therapy, a desired effect of lymph node size reduction was seen on CT scan 22 days later (Figure 3).
case_images: Graph indicating the EBV DNA PCR trends while on intravenous ganciclovir and foscarnet.
case_images: JTRAN2011-919651.004.jpg
case_images: PMC3056220_01_JTRAN2011-919651.004.jpg
case_images: fig4
case_images: This prompted a significant reduction in EBV PCR values to undetectable levels as depicted in Figure 4.