case_images: PMC10932957_01
case_images: (A) Head CT on admission showed a slightly high-density mass in the left occipital lobe. (B) The lesion was hypointense on T1-weighted image. (C) T2-weighted image of head MRI showed hyperintensity of the lesion with surrounding edema. (D) T2-FLAIR image showed mixed signals with ill-defined borders. (E) Axial T1-enhanced image showed patchy mild enhancement of the lesion, part of the lesion encompassed the posterior part of the left lateral ventricle. (F) The head CT at 4 h after operation showed that the tumor was largely removed, and there was no obvious bleeding in the operation area.
case_images: fneur-15-1351674-g001.jpg
case_images: PMC10932957_01_fneur-15-1351674-g001.jpg
case_images: fig1
case_images: Axial T1-enhanced image of head MRI showed patchy mild enhancement of the lesion, part of the lesion encompassed the posterior part of the left lateral ventricle (Figure 1).
case_images: (A) Hematoxylin-eosin staining showed poorly differentiated tumor cells with hyperchromatic nuclei and proliferation of vascular endothelial cells (x100). (B) Immunohistochemical results showed diffuse cytoplasmic glial fibrillary acidic protein (GFAP) immunoreactivity (x100), (C) diffuse cytoplasmic and nuclear S100 immunoreactivity (x100), and (D) diffuse perinuclear epithelial membrane antigen (EMA) immunoreactivity suggestive of ependymal differentiation (x200). (E) Diffuse cytoplasmic and nuclear AE1/AE3 immunoreactivity (x100). (F) Ki-67 proliferation index was approximately 20% (x100).
case_images: fneur-15-1351674-g002.jpg
case_images: PMC10932957_01_fneur-15-1351674-g002.jpg
case_images: fig2
case_images: The pathological diagnosis was anaplastic ependymoma (Figure 2).
case_images: Eight months after operation, head MRI showed multiple cerebrospinal fluid dissemination metastases in the brain. (A) On enhanced magnetic resonance imaging, the arrow points to the tumor metastasis at the brainstem. (B) The arrow points to the metastatic tumor near the right ventricle. (C) The arrow points to a metastatic tumor in front of the right central sulcus.
case_images: fneur-15-1351674-g003.jpg
case_images: PMC10932957_01_fneur-15-1351674-g003.jpg
case_images: fig3
case_images: Eight months after operation, the patient developed frequent epileptic seizures, and head MRI showed multiple cerebrospinal fluid dissemination metastases in the brain (Figure 3).