case_images: PMC11753593_01
case_images: - Contrast-enhanced MRI scan. A) Pelvic MRI transverse section T1 sequence. B) Coronal T2 sequence shows the linear, sheet-like low signal intensity of nerve fibers. C) The B50 sequence shows low signal intensity in the central area, suggesting hemorrhage. D and E) Contrast-enhanced scans of the T1 sequence show heterogeneous enhancement with intact capsule structure and punctate vascular-like enhancement.
case_images: Neurosciences-30-1-59_1.jpg
case_images: PMC11753593_01_Neurosciences-30-1-59_1.jpg
case_images: f1
case_images: MRI revealed a round lesion with low signal intensity on T1-weighted images and high peripheral signal intensity with intermediate to low central intensity on T2-weighted, fat-suppressed images, displaying characteristics such as the "entering-and-exiting-nerve sign" and the "fascicular sign" (Figures 1A-B). Diffusion-weighted imaging (b50) showed low signal intensity (Figure 1C). The lesion measured approximately 21 mm x 24 mm and exhibited multifocal linear enhancement suggestive of vascular structures on contrast-enhanced scans (Figures 1D-E), distinct from the prostate gland.
case_images: - The HE-stained image of the lesion tissues. Arrows indicate the dense area A) and the sparse area (B). In the dense area, tumor cells were spindle-shaped with indistinct cell boundaries. The nuclei of tumor cells were elongated and arranged in a palisade pattern. The tumor cell nuclei were round and deeply stained in the sparse area, with no significant atypia, and mucinous degeneration was observed in small areas. Additionally, a few fibers and striated muscle tissues were visible in the puncture specimen. Scale bars are 100mum.
case_images: Neurosciences-30-1-59_2.jpg
case_images: PMC11753593_01_Neurosciences-30-1-59_2.jpg
case_images: f2
case_images: HE-stained histological examination showed spindle cell proliferation (Figure 2), indicative of a schwannoma characterized by locally active cellular growth.
case_images: - Immunohistochemical staining of the lesion tissues. The images demonstrate strong positive expression of S-100 A) and NSE B), a Ki67 index of 5% C) and a negative expression for CD34 D) and Desmin E) Scale bars are 100 mum.
case_images: Neurosciences-30-1-59_3.jpg
case_images: PMC11753593_01_Neurosciences-30-1-59_3.jpg
case_images: f3
case_images: Immunohistochemical analysis of the biopsy specimen demonstrated positive expression of S-100 and NSE, a Ki67 index of 5%, and negative expression for CD34 and Desmin (Figure 3).