case_images: PMC10378600_01
case_images: Plaques in extensor interphalangeal joints of both hands before and after treatment. (A) Plaques in extensor interphalangeal joints of both hands before treatment. (B) Two months after treatment.
case_images: CCID-16-1893-g0001.jpg
case_images: PMC10378600_01_CCID-16-1893-g0001.jpg
case_images: f0001
case_images: A 45-year-old man presented to our hospital with a six-year history of asymptomatic thick plaques on the extensor aspect of both knuckles and ankles (Figures 1A, 2A and B) that had been histopathologically diagnosed as knuckle pads (Figure 3), denying any repetitive scratching, rubbing to this area or a family history. Several depigmentary rings were seen around the plaques due to long-term use of the glucocorticoid (Figure 1A). Improvement was sustained at 2-month follow-up with enhanced repigmentation of the depigmentary rings around the plaques (Figures 1B, 2C and D).
case_images: Plaques on both ankles before and after treatment. (A and B) Plaques on both ankles before treatment. (C and D) Two months after treatment.
case_images: CCID-16-1893-g0002.jpg
case_images: PMC10378600_01_CCID-16-1893-g0002.jpg
case_images: f0002
case_images: A 45-year-old man presented to our hospital with a six-year history of asymptomatic thick plaques on the extensor aspect of both knuckles and ankles (Figures 1A, 2A and B) that had been histopathologically diagnosed as knuckle pads (Figure 3), denying any repetitive scratching, rubbing to this area or a family history. Improvement was sustained at 2-month follow-up with enhanced repigmentation of the depigmentary rings around the plaques (Figures 1B, 2C and D).
case_images: Histopathology of a plaque on the hand knuckle. (A) Hematoxylin-eosin (H&E) staining shows compact hyperkeratosis, epidermal hyperplasia, elongation of rete ridges and subdermal fibrous tissue hyperplasia (original magnification: 20x). (B) H&E, at a higher magnification of Figure 3A (original magnification: 40x).
case_images: CCID-16-1893-g0003.jpg
case_images: PMC10378600_01_CCID-16-1893-g0003.jpg
case_images: f0003
case_images: A 45-year-old man presented to our hospital with a six-year history of asymptomatic thick plaques on the extensor aspect of both knuckles and ankles (Figures 1A, 2A and B) that had been histopathologically diagnosed as knuckle pads (Figure 3), denying any repetitive scratching, rubbing to this area or a family history.