case_images: PMC10118668_01
case_images: Biopsy of the right gonad showing germ cells intermingled with seminiferous tubules with decreased diameter.
case_images: 2359-4292-aem-62-06-0644-gf01.jpg
case_images: PMC10118668_01_2359-4292-aem-62-06-0644-gf01.jpg
case_images: f1
case_images: The histology revealed bilateral dysgenetic testes with signs of neoplastic transformation on the right gonad (Figure 1).
case_images: Large clear germ cells with prominent nuclei interspersed by other small cells with hyperchromatic nuclei and scant cytoplasm (immature Sertoli cells).
case_images: 2359-4292-aem-62-06-0644-gf02.jpg
case_images: PMC10118668_01_2359-4292-aem-62-06-0644-gf02.jpg
case_images: f2
case_images: The right gonad had two neoplastic lesions: a premalignant one (germ cell cluster, clonal proliferation), within a region of undifferentiated gonadal tissue, and a gonadoblastoma (Figures 2 and 3).
case_images: Germ cells positive for OCT3/4.
case_images: 2359-4292-aem-62-06-0644-gf03.jpg
case_images: PMC10118668_01_2359-4292-aem-62-06-0644-gf03.jpg
case_images: f3
case_images: The right gonad had two neoplastic lesions: a premalignant one (germ cell cluster, clonal proliferation), within a region of undifferentiated gonadal tissue, and a gonadoblastoma (Figures 2 and 3).
case_images: PMC10118668_02