case_images: PMC5733935_01
case_images: This glomerulus demonstrates accentuation of the lobular architecture with associated endocapillary hypercellularity and duplication of the glomerular basement membranes (Jones methenamine silver).
case_images: CRIN2017-7964015.001.jpg
case_images: PMC5733935_01_CRIN2017-7964015.001.jpg
case_images: fig1
case_images: Kidney biopsy showed cellular crescents involving up to 63% of the sampled glomeruli (Figure 4), which demonstrated a membranoproliferative pattern of injury with prominent accentuation of the lobular structure and duplication of the glomerular basement membranes (Figure 1).
case_images: There is granular mesangial and capillary wall immunofluorescence staining for the respective immunoglobulins and complement components that range from 1 to 2+ on a scale of 0-4+.
case_images: CRIN2017-7964015.002.jpg
case_images: PMC5733935_01_CRIN2017-7964015.002.jpg
case_images: fig2
case_images: On a 0-4+ scale, immunofluorescence microscopy demonstrated granular capillary wall and mesangial staining for C3 (2+), C4d (1-2+), C1q (1+), and IgG (1+ in a segmental distribution) (Figure 2).
case_images: Figure demonstrating arteriolar thrombotic microangiopathy.
case_images: CRIN2017-7964015.003.jpg
case_images: PMC5733935_01_CRIN2017-7964015.003.jpg
case_images: fig3
case_images: Additional findings of a thrombotic microangiopathic injury were observed in a hilar arteriole with a thrombus (Figure 3).
case_images: A cellular crescent fills Bowman space adjacent to this glomerulus with prominent endocapillary hypercellularity (Periodic acid-Schiff).
case_images: CRIN2017-7964015.004.jpg
case_images: PMC5733935_01_CRIN2017-7964015.004.jpg
case_images: fig4
case_images: Kidney biopsy showed cellular crescents involving up to 63% of the sampled glomeruli (Figure 4), which demonstrated a membranoproliferative pattern of injury with prominent accentuation of the lobular structure and duplication of the glomerular basement membranes (Figure 1).