case_images: PMC5093277_01
case_images: Psoriasis herpeticum. Erythematous scaly plaques with peripheral hyperpigmentation involving the (a) face, scalp, (b-d) torso, and extremities, with scattered ~1 cm erosions.
case_images: CRIOG2016-5319425.001.jpg
case_images: PMC5093277_01_CRIOG2016-5319425.001.jpg
case_images: fig1
case_images: Cutaneous examination revealed erythematous scaly plaques with peripheral hyperpigmentation involving the scalp, face, arms, abdomen including the umbilicus, and pretibial legs, with scattered ~1 cm erosions within the plaques (Figure 1).
case_images: Psoriasis herpeticum. Punch biopsy specimen of the left leg demonstrating (a) psoriasiform acanthosis, epidermal necrosis, and acantholysis with (b) multinucleate keratinocytes with margination of chromatin and nuclear molding (hematoxylin-eosin stain; original magnification: (a) x40; (b) x400).
case_images: CRIOG2016-5319425.002.jpg
case_images: PMC5093277_01_CRIOG2016-5319425.002.jpg
case_images: fig2
case_images: Punch biopsy of a representative skin lesion revealed psoriasiform acanthosis, epidermal necrosis, and acantholysis, as well as multinucleate keratinocytes with margination of chromatin and nuclear molding (Figure 2).
case_images: Psoriasis herpeticum. Biopsy specimen from Figure 2 showing positivity with HSV type I immunoperoxidase staining (herpes simplex virus type I immunoperoxidase stain; original magnification: x200).
case_images: CRIOG2016-5319425.003.jpg
case_images: PMC5093277_01_CRIOG2016-5319425.003.jpg
case_images: fig3
case_images: Immunoperoxidase staining by monoclonal antibody for HSV type I and type II was positive, in keeping with the frequent cross-reactivity encountered with these antibody preparations (Figure 3).