case_images: PMC11832408_01
case_images: A 68-year-old woman. (A) A CT scan with bone window demonstrates the anterior part of the right temporal bone destruction (white arrow). (B) A Brain CT scan shows a rounded-like soft-tissue density mass in the temporal region. (C-E) MR images depict a dumbbell-shaped intradiploic mass that was iso-hypo signal intensity on T1WI (D) and diffusion sequence (C), and hyperintensity on T2WI (E). (F) The lesion shows intense and heterogeneous enhancement in two parts (white arrow and black arrow, respectively) on contrast-enhanced T1WI. (G) The post-operative contrast-enhanced T1WI revealed no significant enhancement in the lesion region. (H) Pathological examination revealed chordoid meningioma (CNS WHO grade II) with eosinophilic vacuolated tumor cells on a myxoid background.
case_images: fonc-15-1502818-g001.jpg
case_images: PMC11832408_01_fonc-15-1502818-g001.jpg
case_images: f1
case_images: This mass was associated with significant bone destruction and hyperostotic changes in the surrounding bone ( Figures 1A, B ). This mass appeared as an iso-hypo signal intensity on T1-weighted images (T1WIs) and diffusion sequence ( Figures 1C, D ) and as a hyperintense signal on T2-weighted images (T2WIs) ( Figure 1E ). Additionally, gadolinium enhancement of the underlying dura was also observed ( Figure 1F ). The results revealed no significant enhancement in the lesion region, suggesting that the surgical procedure had successfully achieved a complete resection of the tumor, and there was no indication of residual disease ( Figure 1G ). Immunostaining for epithelial membrane antigen (EMA) was positive within the cytoplasm of the neoplastic cells ( Figure 1H ).
case_images: PMC11832408_02
case_images: A 56-year-old man. (A) CT scan with bone window demonstrates the spheno-orbital osteocondensing lesion (white arrow). (B-D) MR images depict the right spheno-fronto-temporo-orbital mass with edema (white arrows) of the surrounding brain parenchyma which showed hyperintensity on T2WI (B), T2-weighted fluid-attenuated inversion recovery (C), and diffusion sequence (D). (E) The lesion shows homogeneous enhancement with involved meningeal enhancement (white arrows) on postcontrast T1-weighted. (F) The post-operative enhanced MRI scans revealed patchy enhancement within the region that was previously occupied by the lesion. (G) Pathological examination revealed meningothelial meningioma (CNS WHO grade I) with epithelioid tumor cells.
case_images: fonc-15-1502818-g002.jpg
case_images: PMC11832408_02_fonc-15-1502818-g002.jpg
case_images: f2
case_images: Brain CT demonstrated an irregular soft-tissue mass in the wing of the sphenoid on the right side, partially extending into the middle cranial fossa ( Figure 2A ). MRI findings showed the lesion to be hypointense relative to the cerebral gray matter on T1-weighted images, hyperintense on T2-weighted and T2-weighted fluid-attenuated inversion recovery images ( Figures 2B, C ), and isointense on diffusion sequences ( Figure 2D ). Post-contrast T1-weighted MRI demonstrated a vividly enhanced mass with dural involvement ( Figure 2E ). The post-operative enhanced MRI scans revealed patchy enhancement within the region that was previously occupied by the lesion, implying the existence of residual disease in the involved dura mater ( Figure 2F ). Immunohistochemistry showed positivity for EMA ( Figure 2G ).