case_images: PMC10783168_01
case_images: Light microscopy: proliferative glomerulus showing lobulation and neutrophilic infiltrate (arrow showing the neutrophilic infiltrate).
case_images: CNCS-12-001-01.jpg
case_images: PMC10783168_01_CNCS-12-001-01.jpg
case_images: Figure1
case_images: AI (normal < 1.0 AI). A renal biopsy was performed (details below and in Figures 1, 2, and 3). Light microscopy: hypercellularity within the glomeruli with mesangial and endocapillary proliferation (Figure 1).
case_images: Immunofluorescence staining: positive for C1q, C3, IgA, IgG, and IgM antibodies, consistent with "full-house" pattern.
case_images: CNCS-12-001-02.jpg
case_images: PMC10783168_01_CNCS-12-001-02.jpg
case_images: Figure2
case_images: AI (normal < 1.0 AI). A renal biopsy was performed (details below and in Figures 1, 2, and 3).  Immunofluorescence: "full-house" positivity for IgG, IgA, IgM, C3, and C1q with 3+ granular capillary staining for IgM and C3 with co-localization of IgG, IgA, and C1q (2+ each) (Figure 2).
case_images: Electron microscopy. A: Fusion of podocytes with expansion of mesangial matrix. B: Subendothelial and rare subepithelial deposits with thickened basement membranes. C: Subendothelial deposits.
case_images: CNCS-12-001-03.jpg
case_images: PMC10783168_01_CNCS-12-001-03.jpg
case_images: Figure3
case_images: AI (normal < 1.0 AI). A renal biopsy was performed (details below and in Figures 1, 2, and 3).  Electron microscopy: diffuse mesangial matrix expansion with increased cellularity and immune-complex deposits (Figure 3).