case_images: PMC11753560_01
case_images: (a) Linear porokeratosis over the left hand and left forearm with nail dystrophy in the left index finger; (b) After 16 weeks of treatment, lesions became lighter in color and flatter; initial treatment with 2% rosuvastatin for 4 weeks, followed by 12 weeks of acitretin 25 mg and 1% 5-fluorouracil. Nail dystrophy in the left index finger also showed improvement; all other nails are normal
case_images: IDOJ-16-152-g001.jpg
case_images: PMC11753560_01_IDOJ-16-152-g001.jpg
case_images: idoj.idoj_901_23-f001
case_images: There were hyperpigmented annular plaques, a few coalescing to form polycyclic lesions arranged linearly over the dorsum of the left index finger, from the left hand up to the mid-left forearm, along with nail dystrophy in the left index finger [Figure 1a and b]. The affected area became lighter in color and flatter [Figure 1b, after 16 weeks].
case_images: Central brownish blotches (blue arrow) along with hypopigmented and erythematous blotches (green arrow) surrounded by a black thread-like border (yellow arrow). Few terminal hairs are also seen (DermLite DL200 HR,Polarized,10x)
case_images: IDOJ-16-152-g002.jpg
case_images: PMC11753560_01_IDOJ-16-152-g002.jpg
case_images: idoj.idoj_901_23-f002
case_images: A few terminal hairs are also seen [Figure 2].
case_images: Epidermis shows a shallow invagination of the floor, which lacks a granular layer, while the wall shows hypergranulosis. Rising from the center of this invagination is a tiny column of parakeratotic cells called coronoid lamella (pink arrow). Moderately dense superficial perivascular patchy lichenoid lymphocytic infiltrate (red arrow) with focal interface vacuolar change (black arrow) (H&E; 10x, 40x)
case_images: IDOJ-16-152-g003.jpg
case_images: PMC11753560_01_IDOJ-16-152-g003.jpg
case_images: idoj.idoj_901_23-f003
case_images: Rising from the center of this invagination is a tiny column of parakeratotic cells (coronoid lamella (CL)), suggesting superficial porokeratosis [Figure 3].