case_images: PMC6754832_01
case_images: Right breast's mass with solid and hyper vascularized components
case_images: PAMJ-33-134-g001.jpg
case_images: PMC6754832_01_PAMJ-33-134-g001.jpg
case_images: f0001
case_images: MRI showed a 12 x 10 x 6cm mass with solid and hyper vascularized components with significant enhancement (Figure 1). Microbiopsies revealed a malignant proliferation made of dilated, branching vascular structures with a high mitotic index reaching 10 mitoses per 10 high power fields evoking a well-differentiated angiosarcoma (Figure 2).
case_images: (A) microphotography showing the vascular nature of the malignant proliferation at low; (B) medium power view
case_images: PAMJ-33-134-g002.jpg
case_images: PMC6754832_01_PAMJ-33-134-g002.jpg
case_images: f0002
case_images: MRI showed a 12 x 10 x 6cm mass with solid and hyper vascularized components with significant enhancement (Figure 1). Microbiopsies revealed a malignant proliferation made of dilated, branching vascular structures with a high mitotic index reaching 10 mitoses per 10 high power fields evoking a well-differentiated angiosarcoma (Figure 2).
case_images: Gross examination revealing the presence of a bluish mass with haemorrhagic changes
case_images: PAMJ-33-134-g003.jpg
case_images: PMC6754832_01_PAMJ-33-134-g003.jpg
case_images: f0003
case_images: The gross examination showed the presence of a 12.5x11x6 cm bluish mass with haemorrhagic changes (Figure 3).
case_images: Microphotography showing the angiosarcomatous proliferation made of endothelial cells
case_images: PAMJ-33-134-g004.jpg
case_images: PMC6754832_01_PAMJ-33-134-g004.jpg
case_images: f0004
case_images: Microscopic examination confirmed the angiosarcomatous proliferation made of endothelial cells focally producing papillary formations and projecting tufts into the lumen of the vessels (Figure 4).
case_images: Microphotography showing intense positivity to anti-CD34 antibodies
case_images: PAMJ-33-134-g005.jpg
case_images: PMC6754832_01_PAMJ-33-134-g005.jpg
case_images: f0005
case_images: The immunohistochemical study confirmed the angiosarcomatous nature of proliferation since there was a diffuse and intense positivity to anti-CD34 and anti-CD31 antibodies (Figure 5).