case_images: PMC6032971_01
case_images: A bluish-violaceous discoloration is seen under her scalp.
case_images: CRIDM2018-8409820.001.jpg
case_images: PMC6032971_01_CRIDM2018-8409820.001.jpg
case_images: fig1
case_images: On initial examination, a large purplish mass on the skin of the frontal scalp was identified [Figure 1].
case_images: The cells are uniformly positive for vimentin, a nonspecific stain that confirms the mesenchymal origin of tumors.
case_images: CRIDM2018-8409820.002.jpg
case_images: PMC6032971_01_CRIDM2018-8409820.002.jpg
case_images: fig2
case_images: An incisional biopsy was performed, which revealed angiosarcoma [Figures 2, 3, and 4].
case_images: The anastomosing channels are readily apparent and are lined with atypical endothelial cells with enlarged and hyperchromatic nuclei.
case_images: CRIDM2018-8409820.003.jpg
case_images: PMC6032971_01_CRIDM2018-8409820.003.jpg
case_images: fig3
case_images: An incisional biopsy was performed, which revealed angiosarcoma [Figures 2, 3, and 4].
case_images: The neoplastic cells also express CD31, a relatively sensitive and specific marker for endothelial cells that is also positive in vascular tumors, including angiosarcoma.
case_images: CRIDM2018-8409820.004.jpg
case_images: PMC6032971_01_CRIDM2018-8409820.004.jpg
case_images: fig4
case_images: An incisional biopsy was performed, which revealed angiosarcoma [Figures 2, 3, and 4].
case_images: A 2.8 cm focal lesion was identified on the anterior aspect of the right submandibular gland representing an enlarged lymph node. A smaller, 1.6 cm enlarged lymph node was also present on the left side.
case_images: CRIDM2018-8409820.005.jpg
case_images: PMC6032971_01_CRIDM2018-8409820.005.jpg
case_images: fig5
case_images: Imaging showed frontal scalp swelling with multiple enlarged lymph nodes concerning metastatic disease [Figure 5].