case_images: PMC11181470_01
case_images: (a) Computed tomography (CT) image showing ill defined T2 hyperintense cystic space occupying lesion in the occipital lobe. (b-c) Squash cytology smears showing cohesive clusters of hyperchromatic tumor cells against a thin mucoidy background and foci of calcification(blue arrow). (b, c: Hematoxylin and Eosin H&E, 200x and 40x.).
case_images: Cytojournal-21-18-g001.jpg
case_images: PMC11181470_01_Cytojournal-21-18-g001.jpg
case_images: F1
case_images: T2 hyperintense cystic space occupying a lesion in the occipital lobe. There is ipsilateral compression of the occipital horn of the ventricle and disproportionate perilesional edema with midline shift [Figure 1a]. Squash smears were moderately cellular and showed cohesive clusters and glandular arrangement of tumor cells against a thin mucoid background [Figure 1b-c].
case_images: Microphotograph panel (a-d) showing well-formed glands and solid sheets of tumor cells with pools of mucin and focal calcification (hematoxylin and eosin stain) (a: 40x, b: 100x, c: 200x, d: 400x), (e) Tumor sections showing immunopositivity for CK7 200x (f) Tumor sections showing immunopositivity for CK20 [IPOX] 200x.
case_images: Cytojournal-21-18-g002.jpg
case_images: PMC11181470_01_Cytojournal-21-18-g002.jpg
case_images: F2
case_images: Histopathology sections showed well-formed glands and sheets of tumor cells with pools of mucin and psammoma bodies confirming the diagnosis of metastatic adenocarcinoma [Figure 2a-d]. In the present case, the tumor cells showed strong immunopositivity for CK7 and were immunonegative for CK20 [Figure 2e and f].