case_images: PMC3250343_01
case_images: Generalized maculopapular skin eruption with exfoliation is observed.
case_images: ymj-53-231-g001.jpg
case_images: PMC3250343_01_ymj-53-231-g001.jpg
case_images: F1
case_images: Physical examination revealed a generalized erythematous maculopapular rash, which gradually became confluent and dusky (Fig. 1).
case_images: Histologic examination of the patient's skin showed subepidermal clefting and bulla formation, with necrotic keratinocytes in the middle and lower epidermis. Vacuolar degeneration was evident in the basal layer, and there was an infiltrate of lymphocytes in the upper dermis and perivascular area (hematoxylin and eosin staining, x100).
case_images: ymj-53-231-g002.jpg
case_images: PMC3250343_01_ymj-53-231-g002.jpg
case_images: F2
case_images: Vacuolar degeneration in the basal layer, and infiltration of lymphocytes in the upper dermis and perivascular area were also observed (Fig. 2).