case_images: PMC2874920_01
case_images: Clinical picture of palpable purpura involvement of bilateral lower extremities.
case_images: GRP2010-597648.001.jpg
case_images: PMC2874920_01_GRP2010-597648.001.jpg
case_images: fig1
case_images: On physical examination, there was pharyngeal erythema, petechiae on the soft palate, cervical lymphadenopathy, a nodular, and nontender, nonblanching purpuric rash involving both upper and lower extremities with nonpitting pedal edema (Figures 1 and 2).
case_images: Clinical picture of palpable purpura involvement of bilateral upper extremities.
case_images: GRP2010-597648.002.jpg
case_images: PMC2874920_01_GRP2010-597648.002.jpg
case_images: fig2
case_images: On physical examination, there was pharyngeal erythema, petechiae on the soft palate, cervical lymphadenopathy, a nodular, and nontender, nonblanching purpuric rash involving both upper and lower extremities with nonpitting pedal edema (Figures 1 and 2).
case_images: Endoscopic finding on EGD showing inflammation, submucosal hemorrhage, and small ulceration.
case_images: GRP2010-597648.003.jpg
case_images: PMC2874920_01_GRP2010-597648.003.jpg
case_images: fig3
case_images: HbsAg: Negative; Anti-HBc IgG: Negative; Mono spot test: Negative; c-ANCA: 0.2 units; p-ANCA: 0.2 units; Stool for occult blood: positive. Esophagogastroduodenoscopy (Figure 3) showed multiple erosions in the duodenum, antrum, and the gastrojejunal anastomotic site. Histopathology (Figures 4 and 5) of the small bowel showed preserved villous architecture, and neutrophilic and eosinophilic infiltrates with leukocytoclastic vasculitis.
case_images: Small bowel biopsy showing preserved villous architecture.
case_images: GRP2010-597648.004.jpg
case_images: PMC2874920_01_GRP2010-597648.004.jpg
case_images: fig4
case_images: HbsAg: Negative; Anti-HBc IgG: Negative; Mono spot test: Negative; c-ANCA: 0.2 units; p-ANCA: 0.2 units; Stool for occult blood: positive. Esophagogastroduodenoscopy (Figure 3) showed multiple erosions in the duodenum, antrum, and the gastrojejunal anastomotic site. Histopathology (Figures 4 and 5) of the small bowel showed preserved villous architecture, and neutrophilic and eosinophilic infiltrates with leukocytoclastic vasculitis.
case_images: Histopathology of HSP involvement in small bowel showing neutrophilic and eosinophilic infiltrates which are seen with karyorrhectic debris.
case_images: GRP2010-597648.005.jpg
case_images: PMC2874920_01_GRP2010-597648.005.jpg
case_images: fig5
case_images: HbsAg: Negative; Anti-HBc IgG: Negative; Mono spot test: Negative; c-ANCA: 0.2 units; p-ANCA: 0.2 units; Stool for occult blood: positive. Esophagogastroduodenoscopy (Figure 3) showed multiple erosions in the duodenum, antrum, and the gastrojejunal anastomotic site. Histopathology (Figures 4 and 5) of the small bowel showed preserved villous architecture, and neutrophilic and eosinophilic infiltrates with leukocytoclastic vasculitis.
case_images: Histopathology of HSP involvement in skin showing microabscess.
case_images: GRP2010-597648.006.jpg
case_images: PMC2874920_01_GRP2010-597648.006.jpg
case_images: fig6
case_images: Skin biopsy (Figure 6) showed pustular leukocytoclastic fibrinoid vasculitis with microabscess.