case_images: PMC6035845_01
case_images: (a) CT brain showed hyperdensity lesion size of 1.5 x 1.8 cm at the left temporal lobe. (b) Chest X-ray revealed patchy infiltration at the left upper lobe.
case_images: CRIPE2018-7041204.001.jpg
case_images: PMC6035845_01_CRIPE2018-7041204.001.jpg
case_images: fig1
case_images: CT brain showed hyperdensity lesion size of 1.5 x 1.8 cm at left temporal lobe with perilesional edema (Figure 1(a)) which was confirmed to be intracerebral hemorrhage. Hematologic and biochemical laboratory tests were described (Table 1), and chest radiography showed consolidation at the left upper lobe (Figure 1(b)).
case_images: The DHR assay of the patient showed complete absence of DHR shift after granulocyte stimulation. The SI was 1.21 which was compatible with XL-CGD. The DHR assay of the patient's mother showed bimodal distribution which was compatible with the XL-CGD carrier. The stimulation index (SI) was calculated by dividing the mean channel of fluorescence intensity in the stimulated cell over the mean channel of fluorescence intensity in the unstimulated cell.
case_images: CRIPE2018-7041204.002.jpg
case_images: PMC6035845_01_CRIPE2018-7041204.002.jpg
case_images: fig2
case_images: The neutrophil dihydrorhodamine (DHR) test revealed no fluorescence detection after granulocyte stimulation. The stimulation index (SI) was 1.21 which was compatible with XL-CGD (Figure 2). The DHR assay was also performed on the mother and revealed bimodal distribution compatible with the XL-CGD carrier (Figure 2).