case_images: PMC8717002_01
case_images: Computed Tomography of the abdomen and pelvis - coronal view. Black arrow pointing to moderate right hydroureteronephrosis. Red arrow pointing to calcium containing lesion measuring 1.9 x 2.1 cm
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case_images: PMC8717002_01_acc-08-03-56-g001.jpg
case_images: acc-08-03-56-g001
case_images: Computed Tomography (CT) of the abdomen and pelvis revealed an ill-defined, hypodense calcium containing lesion measuring 1.9 x 2.1 cm distal to the right iliac bifurcation causing moderate right hydroureteronephrosis (Figure 1).
case_images: Angiomyomatous hamartoma measuring 10 x 5 x 5 cm, excised from right groin
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case_images: PMC8717002_01_acc-08-03-56-g002.jpg
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case_images: The surgeons also excised the right groin cystic mass and sent it for pathology which later resulted as a benign angiomyomatous hamartoma (Figure 2).
case_images: Immunohistochemistry stains show EHE tumor cells are positive for: A. vascular marker Erythroblast transformation-specific-related gene (anti-ERG antibody, x100); B. tumor specific marker Calmodulin-binding transcription activator 1 (anti-CAMTA1 antibody, x100); C. non-specific marker Cluster of differentiation 56 (anti-CD56 antibody, x100); D. vascular marker Cluster of differentiation 31 (anti-CD31 antibody, x100); E. Friend leukemia integration 1 transcription factor (anti-FLI1 antibody, x100). F. cords and single cells of large endothelial cells with abundant eosinophilic cytoplasm embedded in a myxohyaline stroma (HE, x200).
case_images: acc-08-03-56-g003.jpg
case_images: PMC8717002_01_acc-08-03-56-g003.jpg
case_images: acc-08-03-56-g003
case_images: By this time, the patient's retroperitoneal biopsy results returned from Mayo clinic as an epithelioid hemangioendothelioma that was positive for the markers: cluster of differentiation 31 (CD31), erythroblast transformation-specific-related gene (ERG), friend leukemia integration 1 transcription factor (FLI1), calmodulin-binding transcription activator 1 (CAMTA1), and cluster of differentiation 56 (CD56) (Figure 3).