case_images: PMC11130403_01
case_images: PMC11130403_02
case_images: PMC11130403_03
case_images: Site of fissure. The umbilical cord was partially tear close to the newborn and was bleeding arterially.
case_images: fped-12-1397412-g001.jpg
case_images: PMC11130403_03_fped-12-1397412-g001.jpg
case_images: F1
case_images: During delivery by cesarean section, a partial tear of the umbilical cord and arterial hemorrhage were observed at the site where the umbilical cord attached to the child (Figure 1).
case_images: Patient course.
case_images: fped-12-1397412-g002.jpg
case_images: PMC11130403_03_fped-12-1397412-g002.jpg
case_images: F2
case_images: The clinical course described above was consistent with CINCA syndrome/NOMID (Figure 2).
case_images: (A) Pathological photograph of the placenta. The placenta showed mild to moderate neutrophilic infiltration in the omentum, with a very small amount extending into the amnion. (B) Umbilical vein on the placental side. (C) Umbilical artery on the placental side. (D) Umbilical cord on the fetal side. Inflammatory cell infiltrate was stronger on the umbilical cord on the fetal side than on the placental side, and abscess formation was observed in Wharton's jelly. (E,F) Strong magnification of (D). Original magnification: (B,C,F) (x100), (A,E) (x200), and (D) (x20).
case_images: fped-12-1397412-g003.jpg
case_images: PMC11130403_03_fped-12-1397412-g003.jpg
case_images: F3
case_images: The placenta showed mild to moderate neutrophilic infiltration in the omentum, with a very small amount extending into the amnion (Figure 3A). Inflammatory cells of the umbilical cord were more common in the umbilical artery than in the umbilical vein on the placental side (Figures 3B,C). The vessel walls of the umbilical cord had coarse striations, cells were edematous, and abscess formation was observed in Wharton's jelly (Figures 3D-F).
case_images: PMC11130403_04