case_images: PMC9513597_01
case_images: Timeline of clinical symptoms with relevant laboratory parameters and treatments.
case_images: fimmu-13-930031-g001.jpg
case_images: PMC9513597_01_fimmu-13-930031-g001.jpg
case_images: f1
case_images: At 6 weeks post-gene therapy, he developed rapid neurological deterioration with bilateral squint, inability to fix and follow, upgazing episodes, limb dyskinesia and dystonic movements, truncal hypotonia, and encephalopathy (Figure 1).
case_images: Pretreatment MRI-Brain demonstrating T2 hyperintense signal in midbrain (left) and hyperintense Fluid attenuated inversion recovery (FLAIR) signal in both thalami and midbrain (right).
case_images: fimmu-13-930031-g002.jpg
case_images: PMC9513597_01_fimmu-13-930031-g002.jpg
case_images: f2
case_images: MRI demonstrated abnormal T2 signal in thalami and brainstem with some restricted diffusion suggestive of viral encephalitis (Figure 2).