case_images: PMC10628577_01
case_images: CT scan of the emergency room showed hemorrhage in the right cerebellar hemisphere (a). Postoperative CT scans revealed clear axial plane views of the surgically cleansed meningiomas and hematomas (b). (c) An image of a subpleural mass in the left lower lobe with well-defined, well-intact margins, and a slightly less uniform density. After enhancement scanning, there is a little heterogeneous enhancement of the chest occupation, tumor size is about 3.4 cm x 3.2 cm (d). The right cerebellar hemisphere exhibits a patchy confluence of T1-weighted, T2-weighted, and FLAIR signals (e-g); the peripheral T2-weighted edema signal has fuzzy boundaries. (h) After enhancement scanning, tumor tissue shows a faintly heterogeneous enhancement. The size of the tumor in the image is about 4.3 cm x 2.1 cm.
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case_images: An emergency department CT scan of the head revealed cerebral hemorrhage in the right cerebellar hemisphere and vermis (Figure 1a). The results of the examination were as follows: the right cerebellar hemisphere slice images with T1-weighted (Figure 1e), T2-weighted (Figure 1f), and FLAIR (Figure 1g) signals were confusing. A T1-weighted hyperintense and tiny patch of enhancement was visible in the center of the enhanced dissected lesion, while slightly longer T2-weighted edema with blurred boundaries was visible at the periphery of the lesion (Figure 1h). Chest CT of the left subpleural lobe revealed a well-defined subpleural mass with somewhat less uniform density and slightly less uniform enhancement following contrast-enhanced CT (Figure 1c and d). Postoperative CT of the head was performed (Figure 1d). One week after treatment, the patient was transferred to a hospital closer to home for ongoing rehabilitation, and he underwent postoperative CT of the head (Figure 1b).
case_images: Neuropathological features of anaplastic meningioma. Malignant mesenchymal brain tumor, marked cell atypia, and prominent mitotic label (>20/10HFP). HE (x40). The cytoplasmic S-100 immunoreactivity was positive. Ki-67 labeling index shows nuclear immunoreactivity. H3K27me3 and CD34, which are both positively expressed in tumor tissue by immunohistochemistry, were found. Cords of tumor cells with intense Vim immunoreactivity.
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case_images: The immunohistochemical findings were as follows: s-100 (+), a 60% positivity rate of KI-67, H3K27ME3 (+), CD34 (+), Vim (+) and STAT-6(-); the postoperative pathological findings are shown in Figure 2.
case_images: Histopathological features of the needle biopsy of the left lung tumor. HE staining revealed that the tumor tissue does not invade lung tissue (x20), the presence of mitotic segments and microscopic heterogeneity are both obvious (x400). The ki-67 positivity rate is >30%. Tumor cell cords with potent Vim immunoreactivity. Immunohistochemistry staining showed that the tumor was negative for TTF-1 and CK, respectively.
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case_images: When comparing the pathology of head and lung cancers, meningioma metastases to the lung should be considered for left lung tumors identified using needle biopsy (Figure 3): Vim(+), Ki-67 positivity 48%, TTF1(-), and CK(-).