case_images: PMC5437439_01
case_images: CT of the abdomen using pancreatic protocol.
case_images: crg-0011-0219-g01.jpg
case_images: PMC5437439_01_crg-0011-0219-g01.jpg
case_images: F1
case_images: The initial diagnosis was unclear and the patient underwent computed tomography (CT) of the abdomen for further evaluation (Fig. 1).
case_images: EUS image of the pancreas with squamous cell carcinoma.
case_images: crg-0011-0219-g02.jpg
case_images: PMC5437439_01_crg-0011-0219-g02.jpg
case_images: F2
case_images: For further evaluation, endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) was performed (Fig. 2).
case_images: The neoplasm is composed of many malignant cells with round to oval nuclei (HE). a Sheets of malignant cells with round to oval nuclei with thick nuclear membrane. b Prominent nucleoli and high N/C ratio cytoplasm which are eosinophilic granular and moderate to abundant with rather well-defined borders.
case_images: crg-0011-0219-g03.jpg
case_images: PMC5437439_01_crg-0011-0219-g03.jpg
case_images: F3
case_images: FNA samples from the pancreas were sent for pathological examination (Fig. 3).
case_images: The CEA marker (a) is negative, the CK5/6 (b) and P63 (c) markers are positive.
case_images: crg-0011-0219-g04.jpg
case_images: PMC5437439_01_crg-0011-0219-g04.jpg
case_images: F4
case_images: The immunohistochemical studies (Fig. 4) were performed using antihuman antibodies against the following markers: unlike CEA, which was negative in tumor cells, CK5/6 and P63 were strongly positive in tumor cells.
case_images: Abdominal axial CT scan depicting a developed pancreatic SCC.
case_images: crg-0011-0219-g05.jpg
case_images: PMC5437439_01_crg-0011-0219-g05.jpg
case_images: F5
case_images: Four months after chemotherapy, clinical signs continued and abdominal CT was done again (Fig. 5).