case_images: PMC6567292_01
case_images: Patient's pedigree.
case_images: f1000research-8-20192-g0000.jpg
case_images: PMC6567292_01_f1000research-8-20192-g0000.jpg
case_images: f1
case_images: His parents had two children and the family history of the patient was remarkable for a deceased brother at the age of 15 years, who had also ID ( Figure 1).
case_images: Image of the patient's chromosomes.. 
  a) Patient's GTG banded karyotype,
  b) Schematic of normal and derivative chromosomes 2 and 18 and breakpoints regions of chromosomes.
case_images: f1000research-8-20192-g0001.jpg
case_images: PMC6567292_01_f1000research-8-20192-g0001.jpg
case_images: f2
case_images: Conventional cytogenetic analysis revealed that the patient had an insertional translocation: 46, XY, inv ins(18;2)(q11.2;q13q22) ( Figure 2).
case_images: Array-based comparative genomic hybridization chromosomal ideogram and clustering of breakpoints.
case_images: f1000research-8-20192-g0002.jpg
case_images: PMC6567292_01_f1000research-8-20192-g0002.jpg
case_images: f3
case_images: Array CGH did not show any deletion or duplication ( Figure 3).