case_images: PMC10811232_01
case_images: (A, B), enhanced chest CT showed a mass adjacent to spine at the thoracic inlet with uneven density and the tumor is adjacent to 2nd and 3rd posterior ribs. (C, D), enhanced MRI showed a higher signal intensity at the periphery of the tumor on T2-weighted images. The internal signal distribution was found to be heterogeneous, while the tumor margins were clearly demarcated with no apparent signs of adjacent tissue or structure infiltration.
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case_images: PMC10811232_01_fonc-13-1290603-g001.jpg
case_images: f1
case_images: The tumor exhibited well-defined margins, heterogeneous internal density and partial internal enhancement after contrast enhancement ( Figures 1A, B ). Contrast-enhanced magnetic resonance imaging (MRI) revealed high signal intensity at the periphery and moderate signal within the interior on T2-weighted images ( Figures 1C, D ).
case_images: (A, B), H&E staining revealed a homogeneous population of spherical cells with basophilic cytoplasm, and hyperchromatic nuclei (x100 and x200 respectively). (C-F) (immunohistochemistry), (C) showed strong positive expression of CD99 membrane staining. (D) showed strong positive expression of CyclinD1 membrane staining. (E) showed CK marking is negative in tumor cells. (F) showed the proportion of tumor cells exhibiting Ki-67 positivity was approximately 35%.
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case_images: PMC10811232_01_fonc-13-1290603-g002.jpg
case_images: f2
case_images: The tumor was successfully excised en bloc via thoracoscopy, and subsequent histopathological analysis revealed a small round cell malignant tumor ( Figures 2A, B ). The proliferation marker Ki-67 was found to be approximately 35% ( Figures 2C-F ).