case_images: PMC4721013_01
case_images: H&E staining of malignant struma ovarii tissues. H&E staining (a) showed fibrous cores of tissue lined by neoplastic cells which contain large overlapping "ground-glass" nuclei characteristic of thyroid papillary carcinoma. b Metastasis to omentum is shown (H&E, original magnifications x400)
case_images: 12957_2016_776_Fig1_HTML.jpg
case_images: PMC4721013_01_12957_2016_776_Fig1_HTML.jpg
case_images: Fig1
case_images: An intra-operative frozen and permanent paraffin section was proved to be a malignant struma ovarii with multiple foci of papillary thyroid carcinoma (Fig. 1a). The pathologic examination showed no metastatic neoplasm was found, except on the omentum material (Fig. 1b).
case_images: Immunohistochemical (CK19, galetin-3, HBME-1) staining of malignant struma ovarii tissues. a CK19 was diffuse and strong cytoplasmic staining in MSO. b MSO showing strong cytoplasmic staining of galectin-3. c MSO with beautiful complex papillae exhibits a HBME-1 membrane staining pattern (immunohistochemistry, original magnifications x400)
case_images: 12957_2016_776_Fig2_HTML.jpg
case_images: PMC4721013_01_12957_2016_776_Fig2_HTML.jpg
case_images: Fig2
case_images: Immunohistochemically, tumor cells were strongly positive for thyroglobulin (Tg), thyroid transcription factor-1 (TTF-1), galetin-3, cytokeratin-19 (CK19), and human bone marrow endothelial cell-1 (HBME-1) (Fig. 2).
case_images: PMC4721013_02