case_images: PMC2249602_01
case_images: MRI findings one month before initiation of thalidomide, showing marked enhancement of infundibulum (6 mm) and bilateral optic nerves (6 mm).
case_images: 1752-1947-2-27-1.jpg
case_images: PMC2249602_01_1752-1947-2-27-1.jpg
case_images: F1
case_images: Repeat MRI of the brain (see figure 1) had also progressed, now showing more prominent enhancement and thickening of the optic nerves, bilaterally (up to 6 mm in greatest thickness).
case_images: MRI Brain with contrast demonstrating improvement 2 months after initiation of thalidomide.
case_images: 1752-1947-2-27-2.jpg
case_images: PMC2249602_01_1752-1947-2-27-2.jpg
case_images: F2
case_images: After two months of treatment, the patient had radiographic improvement on follow-up MRI scan (see figure 2).
case_images: MRI brain with contrast showing near resolution of enhancement, stable on serial MRIs for 2 years.
case_images: 1752-1947-2-27-3.jpg
case_images: PMC2249602_01_1752-1947-2-27-3.jpg
case_images: F3
case_images: Following another 4 to 10 months of thalidomide, there was complete resolution of all abnormal enhancement on MRI, which has been maintained over the past several years (see figure 3).