case_images: PMC6358352_01
case_images: (A) Histopathology-nasal clear cell carcinoma H&E (magnification x400), (B) Ki-67 (index30%), (C) CD10 (+), (D) CA9 (+), (E) PAX-8 (+), (F) Vimentin (+), (G) EMA (+), (H) AE1/AE3 (+).
case_images: medi-98-e14012-g001.jpg
case_images: PMC6358352_01_medi-98-e14012-g001.jpg
case_images: F1
case_images: CA 9, CD 10, EMA, and Ki-67 (Fig. 1), while SMA, Syn, P 63, CD 34, CgA, HMB 45, and S-100 were negative, which indicated the nasal metastatic tumor had a renal origin. Combination of imaging and histological examination, the patient was diagnosed as CCRCC and nasal metastatic tumor.
case_images: (A) A solitary nasal cutaneous nodule as big as a horsebean. (B) Quickly shrinkage of nasal metastatic tumor after 8-week treatment with axitinib.
case_images: medi-98-e14012-g002.jpg
case_images: PMC6358352_01_medi-98-e14012-g002.jpg
case_images: F2
case_images: The nasal metastasis shrinkage was observed after 8-week treatment with initial dose of 5 mg twice a day (Fig. 2) and the primary tumor was stable.