case_images: PMC11697719_01
case_images: Same-session photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) treatment using two chromophores. a Irradiation with UV-A using a commercially available CXL device; b Irradiation with green light using a custom-built irradiation device
case_images: 40662_2024_420_Fig1_HTML.jpg
case_images: PMC11697719_01_40662_2024_420_Fig1_HTML.jpg
case_images: Fig1
case_images: The remainder of the slit-lamp examination was normal (Fig. 1a). The patient's previous symptoms of ocular pain, photophobia, epiphora, and blepharospasm had resolved (Fig. 1b).
case_images: Photograph of the cornea before and after the same-session dual chromophore photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) treatment. a Prior to initiation of the PACK-CXL treatment, the cornea presented with all signs of acute Acanthamoeba keratitis; b Six months after the third same-session PACK-CXL treatment, the cornea displays a quiescent deep stromal scar
case_images: 40662_2024_420_Fig2_HTML.jpg
case_images: PMC11697719_01_40662_2024_420_Fig2_HTML.jpg
case_images: Fig2
case_images: UV-A light at 18 mW/cm2 for 9 min and 15 s (C-eye device, EMAGine, Zug, Switzerland), corresponding to a total fluence of 10 J/cm2. UV-A irradiation was immediately followed by irradiation with 522 nm green light at 15 mW/cm2 for 6 min, corresponding to a total fluence of 5.4 J/cm2 (Fig. 2).
case_images: Anterior segment-optical coherence tomography. a Before initiation of the photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) therapy, the cornea showed marked edema; b Six months after the third same-session PACK-CXL treatment, the central cornea shows a full-thickness scar and epithelial remodeling
case_images: 40662_2024_420_Fig3_HTML.jpg
case_images: PMC11697719_01_40662_2024_420_Fig3_HTML.jpg
case_images: Fig3
case_images: Following the third combined same-session procedure, the cornea showed resolution of edema (Fig. 3) and a steady decrease in infiltrate size over the next 6 months and presented as a quiescent scar in April 2022.