case_images: PMC8660696_01
case_images: CT images of five patients pre-lung transplantation and post-lung transplantation. (1A-4A) Progression of bilateral lung fibrosis with consolidation were shown in case 1-4. (1B, 2B, 4B, 5B) Post-lung transplantation CT manifestation without significant abnormality. (3B) Chest imaging showed significant lung effusion and edema in Case 3. (5A) Case 5 suffered deteriorated graft function after 5 years of transplantation and chronic lung allograft dysfunction was suspected.
case_images: fsurg-08-754816-g0001.jpg
case_images: PMC8660696_01_fsurg-08-754816-g0001.jpg
case_images: F1
case_images: These patients survived to date with improved respiratory symptoms and no obvious lung abnormalities on CT images (Figures 1.1B, 4B). Upon follow-up, patient has fully recovered renal function and pulmonary imaging was normal (Figure 1.2B). Cardiac arrhythmia and grade 3 primary graft dysfunction occurred sequentially and could not be wean-off ECMO (Figure 1.3B). Lung function showed FEV1 0.48 L and FVC 1.19L with deteriorating chest imaging of chronic lung allograft dysfunction (Figure 1.5A). Bilateral lung transplantation was performed and postoperative recovery period was uneventful (Figure 1.5B).
case_images: Illustration of clinical course and perioperative events in Case 1-4. Pre-lung transplantation and intraoperative mechanical ventilation support, ECMO support modes and duration were illustrated. Post-lung transplantation events were labeled with outcome up to the follow-up date. S, survival; DVT, deep vein thrombosis; AKI, acute kidney injury; POD, post-operation day.
case_images: fsurg-08-754816-g0002.jpg
case_images: PMC8660696_01_fsurg-08-754816-g0002.jpg
case_images: F2
case_images: The clinical course of Case 1-4 are presented in Figure 2.