case_images: PMC11812996_01
case_images: PET-CT revealed the presence of a tumor in the right proximal humerus and end of the clavicle. PET-CT = positron emission tomography-computed tomography.
case_images: medi-104-e41365-g001.jpg
case_images: PMC11812996_01_medi-104-e41365-g001.jpg
case_images: F1
case_images: Furthermore, positron emission tomography/computed tomography confirmed its presence (Fig. 1).
case_images: FISH analysis with PML and RARA double fusion probes demonstrating the presence of PML/RARalpha fusion rearrangement. FISH = fluorescence in situ hybridization.
case_images: medi-104-e41365-g002.jpg
case_images: PMC11812996_01_medi-104-e41365-g002.jpg
case_images: F2
case_images: PML/RARalpha along with one normal signal each for PML and RARalpha, which confirmed the diagnosis (Fig. 2). Pathological promyelocytes (4.0%) were observed in the bone marrow smear (Fig. 3).
case_images: Bone marrow smear showed the proliferation of aberrant promyelocytes (x1000).
case_images: medi-104-e41365-g003.jpg
case_images: PMC11812996_01_medi-104-e41365-g003.jpg
case_images: F3
case_images: PML/RARalpha along with one normal signal each for PML and RARalpha, which confirmed the diagnosis (Fig. 2). Pathological promyelocytes (4.0%) were observed in the bone marrow smear (Fig. 3).
case_images: Flow cytometry scatter plots demonstrating the abnormal promyelocytes expressing CD117, CD13, CD33, and CD56, weakly expressing CD34, but not CD15, CD38, or HLA-Dr.
case_images: medi-104-e41365-g004.jpg
case_images: PMC11812996_01_medi-104-e41365-g004.jpg
case_images: F4
case_images: Flow cytometry detection of the bone marrow confirmed 0.08% of the abnormal promyelocytes expressing CD117, CD13, CD33, and CD56, weakly expressing CD34, but not CD15, CD38, or HLA-DR (Fig. 4).