case_images: PMC11721701_01
case_images: PET/CT scans in Case 1 prior to Clostridioides difficile diagnosis. The maximum intensity projection (MIP) image (a), coronal CT (b), and coronal PET/CT (c) showed no appreciable abnormal uptake in the colon. The PET/CT scans 1 month after treatment of diagnosed C. difficile. The coronal CT (d), coronal PET/CT (e), and MIP image (f) showed diffuse FDG uptake in the colon but without corresponding wall thickening on CT (arrows in (d-f)). This type of uptake was deemed nonspecific stimulation/inflammation from immunotherapy but was not severe enough to meet the diagnosis of colitis.
case_images: jcm-14-00256-g001.jpg
case_images: PMC11721701_01_jcm-14-00256-g001.jpg
case_images: jcm-14-00256-f001
case_images: The radiologist's report indicated that this may have been due to physiologic activity (Figure 1).
case_images: Endoscopic images. Normal appearing colon from Case 1 (A). Edema, erythema, and ulceration from Case 2 (B).
case_images: jcm-14-00256-g002.jpg
case_images: PMC11721701_02_jcm-14-00256-g002.jpg
case_images: jcm-14-00256-f002
case_images: A flexible sigmoidoscopy during the hospital admission revealed edema, erythema, and ulceration in the left colon (Figure 2B).
case_images: PMC11721701_02
case_images: Endoscopic images. Normal appearing colon from Case 1 (A). Edema, erythema, and ulceration from Case 2 (B).
case_images: jcm-14-00256-g002.jpg
case_images: PMC11721701_02_jcm-14-00256-g002.jpg
case_images: jcm-14-00256-f002
case_images: A flexible sigmoidoscopy during the hospital admission revealed edema, erythema, and ulceration in the left colon (Figure 2B).
case_images: A female patient with metastatic left breast carcinoma and receiving immunotherapy. Neither the PET/CT completed 1 month before the colitis episode (maximum intensity projection [MIP] image (a)) nor the one completed 1 month after the colitis episode (MIP image (b)) showed any appreciable abnormal increased uptake in the colon.
case_images: jcm-14-00256-g003.jpg
case_images: PMC11721701_02_jcm-14-00256-g003.jpg
case_images: jcm-14-00256-f003
case_images: Neither the PET/CT completed 1 month prior to the colitis episode nor the one completed 1 month after the colitis episode showed any increased FDG uptake in the colon, which is in huge contrast to the endoscopic findings (Figure 3).