case_images: PMC8716376_01
case_images: Skin examination: (A) lower legs (B) back.
case_images: fonc-11-755750-g001.jpg
case_images: PMC8716376_01_fonc-11-755750-g001.jpg
case_images: f1
case_images: Skin examination showed a purpuric maculopapular rash predominantly located on the lower legs ( Figure 1A ), thighs, buttocks, back ( Figure 1B ) and lower abdomen.
case_images: Skin sample showing intense neutrophilic infiltration of the blood vessels in the dermis with leukocytoclasis; (A) hematoxylin and eosin stain (HE) x20, (B) HE x 40.
case_images: fonc-11-755750-g002.jpg
case_images: PMC8716376_01_fonc-11-755750-g002.jpg
case_images: f2
case_images: A skin biopsy showed a positive immunofluorescence for IgM and C3 within vascular walls, without IgA involvement (thus excluding Henoch-Schonlein purpura) and pathologist concluded to a leukocytoclasic vasculitis ( Figure 2 ).
case_images: Serum levels of carbohydrate antigen 19-9 (CA 19-9) during treatment and follow-up.
case_images: fonc-11-755750-g003.jpg
case_images: PMC8716376_01_fonc-11-755750-g003.jpg
case_images: f3
case_images: Tumor marker decreased by half at the time of vasculitis resolution, to 262 kU/l ( Figure 3 ).