case_images: PMC3979789_01
case_images: Electrophoresis of serum (A) and urine (B). The arrow in the urine electrophoresis indicates the pathological homogenous component that accounted for 53.3% of the urinary proteins in the beta-fraction.
case_images: imcrj-7-071Fig1.jpg
case_images: PMC3979789_01_imcrj-7-071Fig1.jpg
case_images: f1-imcrj-7-071
case_images: The electrophoretic analysis of the serum and urine proteins is shown in Figure 1. The serum electrophoresis pattern showed decreased albumin and increased alpha1-fraction, beta-fraction, and gamma-globulins, suggesting polyclonal gammopathy (Figure 1A). The urine electrophoresis showed increased beta-fraction, which accounted for 53.3% of the urinary proteins (Figure 1B).
case_images: Thigh muscle biopsy.. Notes: (A) Inflammatory cells invading the endomysium within the muscle fascicles (arrows). Hematoxylin and eosin stain (x200 magnification). (B) Immunohistochemical staining for CD8. Activated CD8+ T cell lymphocytes have infiltrated the vastus lateralis muscle (x100 magnification, brown color, arrows).
case_images: imcrj-7-071Fig2.jpg
case_images: PMC3979789_01_imcrj-7-071Fig2.jpg
case_images: f2-imcrj-7-071
case_images: Biopsy of the left vastus lateralis muscle demonstrated endomysial chronic inflammation and muscle fiber necrosis (Figure 2A), and immunohistochemical stain showed infiltration by CD8+ T cells (Figure 2B).