case_images: PMC9597019_01
case_images: A PET-CT scan showed a lesion about 0.7 cm in diameter above the right thigh.
case_images: 10.1177_2632010X221129588-fig1.jpg
case_images: PMC9597019_01_10.1177_2632010X221129588-fig1.jpg
case_images: fig1-2632010X221129588
case_images: In addition, PET-CT examination showed soft tissue nodules in front of the right femur, about 0.7 cm in diameter, with increased expression of somatostatin receptors: it is likely to be a phosphaturic mesenchymal tumor (Figure 1).
case_images: Representative images of histology and immunohistochemistry of case 1. (A and B) H&E
  (10xand 4x) highlighted bland spindle cells, smudgy/grungy basophilic matrix and hemorrhage.
  (C) H&E (10x) showed focal ossification. (D) Immunohistochemistry (20x) demonstrated
  positive staining for FGF-23 in tumour cells.
case_images: 10.1177_2632010X221129588-fig2.jpg
case_images: PMC9597019_01_10.1177_2632010X221129588-fig2.jpg
case_images: fig2-2632010X221129588
case_images: The histology of the postoperative specimens showed that the tumor was composed of bland short spindle cells, smudgy/grungy basophilic matrix, mature adipose tissue, hemorrhage, and focal ossification (Figure 2).
case_images: PMC9597019_02
case_images: A PET-CT scan showed a lesion about 1.5 cm x 1.8 cm in size above the right thigh.
case_images: 10.1177_2632010X221129588-fig3.jpg
case_images: PMC9597019_02_10.1177_2632010X221129588-fig3.jpg
case_images: fig3-2632010X221129588
case_images: And PET-CT showed a slightly low-density nodule in the inner muscle of the right middle thigh, about 1.5 cm x 1.8 cm in size, with increased expression of somatostatin receptors: the possibility of phosphaturic mesenchymal tumor (Figure 3).
case_images: Representative images of histology and immunohistochemistry of case 2. (A and B) H&E
  (20x and 10x) highlighted bland spindle cells, multinucleated giant cells and focal myxoid
  changes. (C) H&E (4x) showed hemangiopericytomatous-like blood vessels and smudgy/grungy
  basophilic matrix. (D) Immunohistochemistry (20x) demonstrated positive staining for FGF-23
  in tumor cells.
case_images: 10.1177_2632010X221129588-fig4.jpg
case_images: PMC9597019_02_10.1177_2632010X221129588-fig4.jpg
case_images: fig4-2632010X221129588
case_images: Smudgy/grungy basophilic matrix, hemangiopericytomatous-like blood vessels, a small number of thick walled vessels, a little adipose tissue, hemorrhage, focal ossification, multinucleated giant cells, and focal myxoid degeneration could be seen (Figure 4).Immunohistochemical staining showed positive for vimentin, SATB2, and CD56, but negative for CD31, CD34, desmin, CD99, Bcl-2, S-100, Syn, CK-pan, and STAT6.