case_images: PMC3432527_01
case_images: APTT with time in control and patients plasma mixed 1 : 1 with normal plasma.
case_images: CRIM.GM2012-203801.001.jpg
case_images: PMC3432527_01_CRIM.GM2012-203801.001.jpg
case_images: fig1
case_images: IX 72% (normal range 51-137%), Factor XI 54% (normal range 59-151%), Factor von Willebrand 136% (normal range 54-150%), Ristocetin CoFactor 143% (normal 70-150%), and bleeding time of 3 minutes 30 seconds (normal range 2-8 minutes). In view of clinical picture, mixing experiments were repeated with a preincubation of up to 3 hours with normal plasma, and samples taken at 0, 1, 2, and 3 hours with the respective controls (Figure 1), which showed the presence of an inhibitor at 2 and 3 hours.
case_images: Endoscopic vision of the duodenal tumor.
case_images: CRIM.GM2012-203801.002.jpg
case_images: PMC3432527_01_CRIM.GM2012-203801.002.jpg
case_images: fig2
case_images: Upper GI endoscopy was carried out which revealed a duodenal tumor (Figures 2(a) and 2(b)), which appeared to be neoplastic, without active hemorrhage, however a biopsy was not taken for the risk of severe bleeding.