case_images: PMC6424055_01
case_images: Clinical presentation of the tumor.
case_images: gr1.jpg
case_images: PMC6424055_01_gr1.jpg
case_images: fig0005
case_images: The lesion appeared to invade the clavicle bone and cervical lymphnodes were not palpable (Fig. 1).
case_images: Intraoperative view of the deep aspect of the tumor invading the clavicle bone.
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case_images: PMC6424055_01_gr2.jpg
case_images: fig0010
case_images: Intraoperative view of the harvesting of two fasciocutaneous flaps.
case_images: gr3.jpg
case_images: PMC6424055_01_gr3.jpg
case_images: fig0015
case_images: The wound closed by layers at the end of the surgical procedure.
case_images: gr4.jpg
case_images: PMC6424055_01_gr4.jpg
case_images: fig0020
case_images: Dermal infiltration by neoplastic proliferation with pushing margins (A); this neoplastic proliferation has a solid, trabecular and pseudoglandular growth pattern (B), with focal areas of comedonecrosis and extensive areas of coagulative necrosis and hemorragia (C); the tumor cells are large with abundant eosinophilic cytoplasm and nuclei with finely dispersed chromatin and prominent nucleoli, there are many atypical mitotic figures (D). Hematoxylin-eosin stain.
case_images: gr5.jpg
case_images: PMC6424055_01_gr5.jpg
case_images: fig0025
case_images: Punch biopsy came back positive for moderately differentiated adenocarcinoma composed by cells with abundant cytoplasm, nuclei with dispersed chromatin and prominent nucleoli. Hematoxylin-eosin stain.
case_images: gr7.jpg
case_images: PMC6424055_01_gr7.jpg
case_images: fig0035
case_images: A punch biopsy was performed that came back positive for moderately differentiated adenocarcinoma composed by cells with abundant cytoplasm, nuclei with dispersed chromatin and prominent nucleoli (Fig. 7) positive stain CK AE1-AE3 and CDX2 (Fig. 8).