case_images: PMC11154143_01
case_images: Hypercellular lesions composed of glial cells with atypia and increased mitotic activity and dysplastic neurons with the hypercellular area and adjacent parenchyma in the 200X section of hematoxylin and eosin stain (A) and immunohistochemical p53 expression in the majority of glial cells (B) at initial diagnosis. The recurrent specimens in the 200X section of hematoxylin and eosin stain showed evident microvascular proliferation and equivocal necrosis (C) and immunohistochemically, the tumors are diffusely positive for GFAP, focally positive for p53 (D).
case_images: vdae072_fig1.jpg
case_images: PMC11154143_01_vdae072_fig1.jpg
case_images: F1
case_images: The pathology of the diagnosis and the recurrent specimens are presented in Figure 1.
case_images: The enhancement in the left temporal lobe to the insula area with leptomeningeal seeding on the axial view of the T1-weighted with contrast (A) and T2-weighted fluid-attenuated inversion recovery with contrast (B) brain magnetic resonance imaging at recurrence before surgery. The axial view of an 18F-Fluciclovine amino acid positron emission tomography (C). Imaging series and treatment course of the patient (D).
case_images: vdae072_fig2.jpg
case_images: PMC11154143_01_vdae072_fig2.jpg
case_images: F2
case_images: The MRI and positron emission tomography scan during the recurrence and further details of his treatment course are summarized in Figure 2, with serial MRI images demonstrating the response.