case_images: PMC8736701_01
case_images: Extensive port-wine stain since birth.
case_images: CRIDM2021-3616429.001.jpg
case_images: PMC8736701_01_CRIDM2021-3616429.001.jpg
case_images: fig1
case_images: Multiple erythematous/hyperpigmented macules.
case_images: CRIDM2021-3616429.002.jpg
case_images: PMC8736701_01_CRIDM2021-3616429.002.jpg
case_images: fig2
case_images: Multiple erythematous and/or hyperpigmented punched-out lesions, some with scaly appearance and/or atrophic surface, were noted on the trunk and proximal parts of extremities (Figure 2).
case_images: Dermal infiltration of spindle cells in a collagenous stroma containing abundant mucin intermixed with some mast cells.
case_images: CRIDM2021-3616429.003.jpg
case_images: PMC8736701_01_CRIDM2021-3616429.003.jpg
case_images: fig3
case_images: Histopathologic assessment showed dermal infiltration of spindle cells in a collagenous stroma containing abundant mucin intermixed with some mast cells which was more compatible with "progressive mucinous histiocytosis" (Figures 3 and 4). "Cutaneous mucinosis of infancy" and "self-healing juvenile cutaneous mucinosis" were also suggested as differential diagnoses.
case_images: A magnified view of histopathological changes seen in the patient's tissue sample.
case_images: CRIDM2021-3616429.004.jpg
case_images: PMC8736701_01_CRIDM2021-3616429.004.jpg
case_images: fig4
case_images: Histopathologic assessment showed dermal infiltration of spindle cells in a collagenous stroma containing abundant mucin intermixed with some mast cells which was more compatible with "progressive mucinous histiocytosis" (Figures 3 and 4). "Cutaneous mucinosis of infancy" and "self-healing juvenile cutaneous mucinosis" were also suggested as differential diagnoses.
case_images: PMC8736701_02
case_images: Remarkable resolution of port-wine stain following PDL therapy.
case_images: CRIDM2021-3616429.005.jpg
case_images: PMC8736701_02_CRIDM2021-3616429.005.jpg
case_images: fig5
case_images: Her port-wine stain considerably improved following 4 sessions of PDL (pulsed-dye laser) therapy and other cutaneous lesions getting better spontaneously (Figures 5 and 6).
case_images: Spontaneous resolution of cutaneous lesions of NLE.
case_images: CRIDM2021-3616429.006.jpg
case_images: PMC8736701_02_CRIDM2021-3616429.006.jpg
case_images: fig6
case_images: Her port-wine stain considerably improved following 4 sessions of PDL (pulsed-dye laser) therapy and other cutaneous lesions getting better spontaneously (Figures 5 and 6).