case_images: PMC5726706_01
case_images: Erythematous, edematous annular plaques with centrifugal growth
case_images: abd-92-05-s1-0145-g01.jpg
case_images: PMC5726706_01_abd-92-05-s1-0145-g01.jpg
case_images: f1
case_images: Forty-one-year-old female patient, phototype IV, with recurrent, itchy, erythematous-edematous annular plaques, with overlying vesicles and crusts on the trunk and limbs for 3 years (Figures 1 and 2).
case_images: Erythematous, edematous plaques with overlying vesicles in a herpetiform
  pattern
case_images: abd-92-05-s1-0145-g02.jpg
case_images: PMC5726706_01_abd-92-05-s1-0145-g02.jpg
case_images: f2
case_images: Forty-one-year-old female patient, phototype IV, with recurrent, itchy, erythematous-edematous annular plaques, with overlying vesicles and crusts on the trunk and limbs for 3 years (Figures 1 and 2).
case_images: Exocytosis and mild acantholysis simulating spongiosis, besides
  predominantly mononuclear perivascular inflammatory infiltrate
  (Hematoxylin & eosin, X100)
case_images: abd-92-05-s1-0145-g03.jpg
case_images: PMC5726706_01_abd-92-05-s1-0145-g03.jpg
case_images: f3
case_images: Histopathology revealed mild acantholysis simulating spongiosis, exocytosis and perivascular inflammatory infiltrate in one of the biopsies, and acantholytic vesicle containing neutrophils and eosinophils in the other (Figures 3 and 4).
case_images: Intraepidermal acantholytic blister with numerous eosinophils, also seen
  in the adjacent epidermis (Hematoxylin & eosin, X100)
case_images: abd-92-05-s1-0145-g04.jpg
case_images: PMC5726706_01_abd-92-05-s1-0145-g04.jpg
case_images: f4
case_images: Histopathology revealed mild acantholysis simulating spongiosis, exocytosis and perivascular inflammatory infiltrate in one of the biopsies, and acantholytic vesicle containing neutrophils and eosinophils in the other (Figures 3 and 4).
case_images: Deposition of IgG in an intercellular pattern all over the epidermis
  (IFD, X100)
case_images: abd-92-05-s1-0145-g05.jpg
case_images: PMC5726706_01_abd-92-05-s1-0145-g05.jpg
case_images: f5
case_images: DIF demonstrated intercellular IgG and C3 in the epidermis, in a pemphigus pattern, ruling out the previous suspicions of DH, that would present with a deposit at the top of dermal papillae and LABD, that would present with a linear deposit of IgA along the basement membrane zone (Figure 5).