case_images: PMC6698641_01
case_images: MRCP A The gallbladder wall was significantly thickened to a thickness of 1.47 cm. There was no acute inflammatory change in the gallbladder (white arrow); no bile duct dilatation, no stones in the gallbladder, thickening of the bile duct wall, and inflammation (blue arrow); B The gallbladder cavity is reduced (white arrow), the bile duct is 6.0 mm wide, and the lumen is changed in a thin line (blue arrow).
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case_images: MRCP (Fig. 1): acute cholecystitis, thickening of the gallbladder wall (1.47 cm), no stones in the gallbladder cavity; no obstruction in the biliary tract; full liver morphology, increased spleen volume; effusion in the perihepatic and spleen weeks.
case_images: Gallbladder solid specimen (visual view) Generally seen: size about 8.0 x 3.0 cm, gallbladder wall is pale, wall thickness edema, gallbladder cavity is significantly reduced, a small amount of bile can be seen in the cavity.
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case_images: Pathological results (Fig. 2, Fig. 3) showed that atypical lymphocytes were seen by HE staining of gallbladder; lamina propria and muscle layer of gallbladder mucosa were infiltrated with atypical lymphoid cells, see mitotic figures; immunohistochemical markers: interstitial cells: Ki67 > 80%, CD3 (+); pathological diagnosis: malignant tumor of the gallbladder lymphoid hematopoietic system.
case_images: Bone marrow biopsy results.. A (HE staining, 10 x 40): A small amount of bone marrow hematopoietic tissue can be seen, lymphoid cells are scattered and karyotype is irregular; B (immunotactic CD3, 10 x 40): labeling result CD3(+), CD235a erythroid (+), MPO granule (+), CD2 (+), CD56 (+), EBER (+).
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case_images: Bone marrow biopsy results (Fig. 4) suggest a diagnosis of bone marrow non-Hodgkin's lymphoma, NK/T cell tumor.