case_images: PMC3861598_01
case_images: (A) Dark red maculopapules on the chest. (B) Multiple dark-red maculopapules on the lower extremities.
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case_images: PMC3861598_01_OL-07-01-0275-g00.jpg
case_images: f1-ol-07-01-0275
case_images: A 35-year-old male presented to Cangzhou Central Hospital (Cangzhou, China) in September 2009 with multiple dark red maculopapules on the trunk and limbs (Fig. 1).
case_images: Hematoxylin-eosin stain of small, irregularly branched blood vessels proliferating throughout the dermis and embedded in a desmoplastic stroma at magnifications (A) x40 and (B) x200.
case_images: OL-07-01-0275-g01.jpg
case_images: PMC3861598_01_OL-07-01-0275-g01.jpg
case_images: f2-ol-07-01-0275
case_images: The tumors were of the same histopathology and demonstrated proliferation of irregularly branched, thin-walled venules infiltrating the sclerotic dermal collagen and the presence of few blood vessels with inconspicuous lumina (Fig. 2A). A mixture of flat and plump endothelial cells was observed (Fig. 2B), however, there was an absence of cellular atypia and mitotic figures.
case_images: Endothelial cells of the proliferative vessels expressed (A) CD31, (B) CD34 and (C) factor VIII. (D) The pericytes expressed SMA and (E) HHF-35 (magnification, x400).
case_images: OL-07-01-0275-g02.jpg
case_images: PMC3861598_01_OL-07-01-0275-g02.jpg
case_images: f3-ol-07-01-0275
case_images: Immunohistochemically, the endothelial cells of the proliferating vessels expressed CD31 (Fig. 3A), CD34 (Fig. 3B) and factor VIII (Fig. 3C). The pericytes expressed SMA (Fig. 3D) and HHF-35 (Fig. 3E).