case_images: PMC4531763_01
case_images: Chest PA shows well-marginated huge left suprahilar mass shadow.
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case_images: PMC4531763_01_kjim-15-2-142-9f1.jpg
case_images: f1-kjim-15-2-142-9
case_images: Chest X-ray (Figure 1) and chest CT scan (Figure 2) revealed a 12x10 cm-sized well-defined and partially capsulated and lobulated homogeneous attenuated mass in the anterior mediastinum.
case_images: Chest CT shows 12x10cm-sized well-defined, partially capsulated and lobulated homogenous attenuated mass in the anterior mediastinum.
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case_images: PMC4531763_01_kjim-15-2-142-9f2.jpg
case_images: f2-kjim-15-2-142-9
case_images: Chest X-ray (Figure 1) and chest CT scan (Figure 2) revealed a 12x10 cm-sized well-defined and partially capsulated and lobulated homogeneous attenuated mass in the anterior mediastinum.
case_images: The light microscopic section shows a predominantly diffuse pattern of monotonous neoplastic cells arranged in organoid cell nests (classic "Zellballen" pattern) that are characteristics of paraganglioma.
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case_images: PMC4531763_01_kjim-15-2-142-9f3.jpg
case_images: f3-kjim-15-2-142-9
case_images: Light microscopic sections showed a predominantly diffuse pattern of monotonous neoplastic cells arranged in organoid cell nests (classic "Zellballen" pattern) that are characteristics of paraganglioma (Figure 3).
case_images: Immunohistochemical stain reveals a positive for S-100 protein in scattered supporting cells.
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case_images: PMC4531763_01_kjim-15-2-142-9f4.jpg
case_images: f4-kjim-15-2-142-9
case_images: Immunoreactivity for S-100 protein, confirming the presence of sustentacular cells which are characteristics of paraganglioma, was detected in scattered supporting cells, mostly at the periphery of the tumor cell nests(Figure 4).