case_images: PMC5308515_01
case_images: (a, b) A 48-day-old full-term male infant with an enormous violaceous mass extending to the chest wall and (c, d) MRI showing the presence of voluminous masses surrounding the thorax.
case_images: 10.1177_2050313X16684742-fig1.jpg
case_images: PMC5308515_01_10.1177_2050313X16684742-fig1.jpg
case_images: fig1-2050313X16684742
case_images: A 48-day-old full-term male infant was presented to the Department of Hemangioma & Vascular Malformation, with an enormous violaceous mass extending to the chest wall (Figure 1). Magnetic resonance imaging (MRI) confirmed the presence of voluminous masses surrounding the thorax (Figure 1).
case_images: Relevant hematological investigations carried out during hospital stay.
case_images: 10.1177_2050313X16684742-fig4.jpg
case_images: PMC5308515_01_10.1177_2050313X16684742-fig4.jpg
case_images: fig4-2050313X16684742
case_images: As shown in Figure 2, the predominant neoplastic component of KHE recapitulated the phenotype of blood vascular endothelium (CD31 and CD34 positive), whereas the epithelioid or glomeruloid islands located within the vascular nodules appeared to represent specialized zones in which PLT trapping and blood destruction occurred, suggesting KHE.
case_images: (a) Hematoxylin-eosin (HE) staining x40 (red arrows: epithelioid or glomeruloid islands, green arrows: enlarged lymphagion); (b) HE x100; (c) HE x200; (d) AAT+; (e) CD31+; (f) CD34+; and (g) Fli-1+.
case_images: 10.1177_2050313X16684742-fig2.jpg
case_images: PMC5308515_01_10.1177_2050313X16684742-fig2.jpg
case_images: fig2-2050313X16684742
case_images: After a 9-month follow-up, the infant lived a healthy life with no evidence of the recurrence of disease (Figure 3).