case_images: PMC10752034_01
case_images: Clinical image of erythematous plaques with scales on the palms and soles accompanied with knuckle pads on the back of the hands before treatment.
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case_images: Dermatological examination revealed erythematous plaques and scales on both palms and soles (Figure 1).
case_images: Histopathological feature revealed (A) hyperkeratosis and acanthosis; (B) vasodilatation and perivascular lymphocytic infiltrates (red arrows).
case_images: CCID-16-3713-g0002.jpg
case_images: PMC10752034_01_CCID-16-3713-g0002.jpg
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case_images: The dermis consists of stromal connective tissue covered with perivascular lymphocytic inflammatory cells, which corresponds to palmoplantar keratoderma (Figure 2).
case_images: Improvement of skin lesions after capecitabine was discontinued.
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case_images: The improvement in the skin lesions was more pronounced after capecitabine was discontinued by the hematology and oncology clinic (Figure 3).