case_images: PMC4998242_01
case_images: Metaphase fluorescent in situ hybridization (FISH) using the probe in the Smith-Magenis syndrome (SMS, OMIM 182290). The red area shows the control the green gene responsible for SMS. FISH = fluorescent in situ hybridization, SMS = Smith-Magenis syndrome.
case_images: medi-95-e2362-g001.jpg
case_images: PMC4998242_01_medi-95-e2362-g001.jpg
case_images: F1
case_images: Owing to persistence of tachypnia, mild hypotonia, feeding difficulties, sleep disturbances, and mild dysmorphic facial features observed clearly such as a flat, broad nasal bridge and small mandible, suspicion of genetic abnormalities were considered and blood samples were sent for chromosome analysis and for FISH testing (Figure 1).