case_images: PMC8478086_01
case_images: A 4-cm, protruding, ulcerated, fleshy, firm tumor with a moist and granular surface.
case_images: CCID-14-1351-g0001.jpg
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case_images: Multiple scaly erythematous papules with yellowish crusts were observed on the margins of the lesion (Figure 1).
case_images: Basaloid neoplasm in lobules and sebaceous cells with vacuolated cytoplasm in the dermis (hematoxylin and eosin; magnification: 10x10).
case_images: CCID-14-1351-g0002.jpg
case_images: PMC8478086_01_CCID-14-1351-g0002.jpg
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case_images: Histopathology demonstrated a basaloid neoplasm in lobules and sebaceous cells with vacuolated cytoplasm in the dermis under low power observation (magnification: 10x10) (Figure 2).
case_images: Ample coarse cells with atypical nuclei (magnification: 40x10).
case_images: CCID-14-1351-g0003.jpg
case_images: PMC8478086_01_CCID-14-1351-g0003.jpg
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case_images: In addition, ample coarse cells with atypical nuclei were found at high magnification (magnification: 40x10) (Figure 3).
case_images: Positive immunohistochemical epithelial membrane antigen stain (magnification: 10x10).
case_images: CCID-14-1351-g0004.jpg
case_images: PMC8478086_01_CCID-14-1351-g0004.jpg
case_images: f0004
case_images: Immunohistochemical staining, including a positive epithelial membrane antigen (EMA) stain (Figure 4), confirmed sebaceous differentiation of the anaplastic cells, supporting the diagnosis of SC.
case_images: Timeline.
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case_images: PMC8478086_01_CCID-14-1351-g0005.jpg
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case_images: Unfortunately, the patient died of unknown causes before initiation of the planned tests and treatment (please see Figure 5:Timeline).