case_images: PMC516788_01
case_images: Mammography of the patients' breasts (A: mediolateral oblique, view B: craniocaudal view)
case_images: 1477-7819-2-29-1.jpg
case_images: PMC516788_01_1477-7819-2-29-1.jpg
case_images: F1
case_images: Photomicrograph showing nuclear pleomorphism, binucleated and multinucleated plasma cells with enlarged nucleoli (Hematoxylin & Eosin).
case_images: 1477-7819-2-29-2.jpg
case_images: PMC516788_01_1477-7819-2-29-2.jpg
case_images: F2
case_images: Mitosis, necrosis, nuclear pleomorphism and binucleated and multinucleated plasma cells were seen. (Figure 2) Additional studies such as serum protein electrophoresis and immunoelectrophoresis were normal.
case_images: Lambda and kappa immunohistochemical stain showing strong and diffuse positivity for lambda (a) and negativity for kappa (b).
case_images: 1477-7819-2-29-3.jpg
case_images: PMC516788_01_1477-7819-2-29-3.jpg
case_images: F3
case_images: Ki67 immunohistochemical stain showing 50-80% nuclear positivity
case_images: 1477-7819-2-29-4.jpg
case_images: PMC516788_01_1477-7819-2-29-4.jpg
case_images: F4
case_images: Nuclear prognostic marker (Ki67) showed 50% to 80% nuclear expression indicative of high proliferative activity and suggesting a plasmacytic tumor with anaplastic components (Figure 4).