case_images: PMC11026575_01
case_images: Cerebral CT changes.
case_images: fped-12-1351478-g001.jpg
case_images: PMC11026575_01_fped-12-1351478-g001.jpg
case_images: F1
case_images: Immunoglobulin G and complement slightly decreased; absolute T-cell value and absolute NK-cell value slightly decreased; arterial blood gas, blood lactate, and blood ammonia were normal; no obvious abnormality was found in cranial brain CT before hospital admission (Figure 1A). Encephalopathy (Figure 1A). Electroencephalogram (EEG): Abnormal EEG in a child, with slow background activity and head bursts of slow and sharp waves after wakefulness and sleep phases.
case_images: Cerebral MRI changes.
case_images: fped-12-1351478-g002.jpg
case_images: PMC11026575_01_fped-12-1351478-g002.jpg
case_images: F2
case_images: After 96 h of treatment, the child had no fever, clear consciousness, cognitive impairment, obvious response to pain stimulation, increased muscle tone in both lower limbs, muscle strength was available, pathological signs were still positive, and cranial magnetic resonance examination suggested that the necrotic lesion had shrunk compared with the previous one (Figure 2A). After 13 days of treatment, the child's limb muscle tone and strength were slightly better than before, the pathological signs were negative, and the cranial magnetic resonance lesion was further reduced compared with before (Figure 2B). The review of the electroencephalogram showed a normal child's electroencephalogram, with slightly slower background activity, and the cranial magnetic resonance suggested that the lesion had shrunk considerably (Figure 2C). Two months after the onset of the disease, the child was fluent in speech, mobile and cognitively normal. Repeat cranial magnetic resonance showed that the necrotic lesion was further reduced and partially disappeared (Figure 2D).