case_images: PMC10066873_01
case_images: Imaging features of patients. (a) The density of the liver parenchyma increases diffusively in the CT portal vein stage, with a CT value of approximately 96 HU. Liver tissue sampling points (arrows). (b) In the magnetic resonance imaging T2 stage, the signals of the liver and spleen were low.
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case_images: Further, enhanced computed tomography (CT) showed a large liver volume, a moderate proportion of liver lobes, small wavy change in the left edge of the liver lobe, diffuse increase in the density of liver parenchyma, and a CT value of approximately 96 HU (Figure 1a). In addition, magnetic resonance imaging showed low signals in both the liver and spleen (Figure 1b), indicating hemochromatosis.
case_images: Pathological features of the liver tissue. (a) Hepatocytes filled with iron particles (arrow). Hematoxylin-eosin staining (10 x 20). (b) The portal area covered with blue iron particles (arrows). Prussian iron staining (10 x 20). (c) Immunohistochemical staining for cytokeratin 7 shows hyperplasia of the bile duct and deposition of iron particles in the bile duct (arrow; 10 x 20). (d) Deperiodic acid-Schiff staining shows iron particles in the macrophages (arrow; 10 x 20).
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case_images: The pathological characteristics of the liver biopsy are shown in Figure 2.