case_images: PMC5156792_01
case_images: Computed tomography (CT) images, axial (a) and coronal (b), of the pelvis showing a huge mass involving bladder and rectum.
case_images: CRIE2016-6308058.001.jpg
case_images: PMC5156792_01_CRIE2016-6308058.001.jpg
case_images: fig1
case_images: Total body computed tomography (TBCT) (Figures 1(a)-1(b)) revealed a voluminous prostate gland (maximum diameter of 10 cm) heterogeneously enhancing the contrast medium.
case_images: 68 Gallium DOTATATE PET/CT image showing a high and diffuse uptake of the prostate.
case_images: CRIE2016-6308058.002.jpg
case_images: PMC5156792_01_CRIE2016-6308058.002.jpg
case_images: fig2
case_images: A subsequent 68 Gallium DOTATATE PET/CT found a high uptake of the whole prostate (SUV max 12.7) and of the adjacent lymph nodes, confirming the presence of a neuroendocrine tumour in that site and excluding other distant metastases (Figure 2).
case_images: (a) Immunohistochemical stain showing tumour cell positive for ACTH (x40). (b) Immunohistochemical stain showing tumour cell positive for calcitonin (x20).
case_images: CRIE2016-6308058.003.jpg
case_images: PMC5156792_01_CRIE2016-6308058.003.jpg
case_images: fig3
case_images: The patient underwent a transurethral prostate biopsy that showed a small cell prostate cancer focally positive for ACTH and calcitonin and negative for chromogranin A and PSA at immunocytochemistry (Figures 3(a) and 3(b)).