case_images: PMC11832387_01
case_images: Chest computed tomography reveals left lung nodule and enlarged #11L lymph node (A, B), and multiple lung nodules in the area with obvious fibrotic changes (C, D).
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case_images: Chest computed tomography (CT) revealed multiple nodules measuring from 8mm to 20mm in diameter located in bilateral lung, along with an enlarged #11L lymph node ( Figures 1A-D ).
case_images: Pathology result of CT-guided percutaneous lung biopsy. Hematoxylin-eosin staining showed poorly differentiated adenocarcinoma like hepatocellular carcinoma (A, B). Immunohistochemical staining showed negative for TTF-1 (C) and positive for Hepatocyte (D) and CK8/18 (E), as well as Ki-67 40% (F).
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case_images: Hematoxylin and eosin staining indicated the poorly differentiated cancer cells resembling hepatocellular carcinoma ( Figures 2A, B ). Immunohistochemical staining showed that the tumor cells were negative for TTF-1 ( Figure 2C ), but positive for Hepatocyte ( Figure 2D ) and CK8/18 ( Figure 2E ), with moderate positivity for Ki-67 (40%,  Figure 2F ).
case_images: Flow chart of diagnosis and treatment process.
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case_images: f3