case_images: PMC4202553_01
case_images: Deep heel fissure and plantar hyperkeratosis
case_images: BCN-4-088-g001.jpg
case_images: PMC4202553_01_BCN-4-088-g001.jpg
case_images: F0001
case_images: He presented with insensitivity to pain, palmoplantar hyperkeratosis, deep heel fissures (Fig. 1), amputation of left big toe, hypodontia (Fig. 2), dystrophic nails, non-healing ulcers, intellectual disability, anhidrosis, polyuria, polydypsia, hyperactivity, and stuttering.