case_images: PMC4737842_01
case_images: (A) Generalized erythematous papulosquamous lesions with whitish scales on the trunk (inlet) and erythematous papular lesion with whitish scales. (B) Improved skin lesions with remaining widespread hypopigmentation 8 weeks after the start of therapy. Some hyperpigmented spots corresponding to hair follicles were suspected to be due to repigmentation.
case_images: ad-28-90-g001.jpg
case_images: PMC4737842_01_ad-28-90-g001.jpg
case_images: F1
case_images: The eruptions were composed of papulosquamous lesions with whitish scales, and the clinical features were similar to those of psoriasis (Fig. 1A). These treatments were effective and the skin lesions were significantly improved, with widespread hypopigmented patches remaining (Fig. 1B).
case_images: Histopathology of skin lesions (H&E, x100). Interface dermatitis with perivascular and periappendageal lymphocytic infiltration, apoptotic keratinocytes, exocytosis of lymphocytes, hyperkeratosis, and parakeratosis (inlet, x400); dyskeratotic cells seen in the epidermis.
case_images: ad-28-90-g002.jpg
case_images: PMC4737842_01_ad-28-90-g002.jpg
case_images: F2
case_images: A histopathological examination of the arm indicated interface dermatitis with perivascular lymphocytic infiltration in the upper dermis, keratinocyte apoptosis, exocytosis of lymphocytes, hyperkeratosis, and parakeratosis (Fig. 2).