case_images: PMC5732958_01
case_images: Second generation sequencing for FXOP3 gene mutation identification and DNA Sanger sequencing for the healthy siblings. (A) Proband. (B) The mother. (C) Older brother (Donor). (D) Younger sister.
case_images: fped-05-00267-g001.jpg
case_images: PMC5732958_01_fped-05-00267-g001.jpg
case_images: F1
case_images: R397Q) mutation in exon 11 of the FOXP3 gene (Figure 1A). The patient's mother is a healthy carrier (Figure 1B). Two healthy siblings were excluded the same mutation by DNA Sanger sequencing (Figures 1C,D).