case_images: PMC3025371_01
case_images: PMC3025371_02
case_images: (a) Endoscopic appearance of the ileal pouch before starting infliximab therapy showing diffuse inflammation. (b) Histology of the ileal pouch before starting infliximab therapy showing focal moderate ulceration and cryptitis with a crypt abscess. (c) Histology of the ileal pouch before starting infliximab therapy showing focal chronic regenerative glandular changes.
case_images: GRP2010-860394.001.jpg
case_images: PMC3025371_02_GRP2010-860394.001.jpg
case_images: fig1
case_images: After another severe exacerbation a year later, the pouch was found to be grossly inflamed with diffuse ulcerations (Figure 1(a)). The biopsies showed mild to moderate active chronic inflammation, cryptitis, and crypt abscesses without any granulomas (Figures 1(b) and 1(c)). 
case_images: PMC3025371_03
case_images: PMC3025371_04
case_images: (a) Normal endoscopic appearance of the ileal pouch after infliximab therapy. (b) Normal histology of the ileal pouch after infliximab therapy.
case_images: GRP2010-860394.002.jpg
case_images: PMC3025371_04_GRP2010-860394.002.jpg
case_images: fig2
case_images: The most recent endoscopy of the pouch (after two years of infliximab therapy) revealed completely normal mucosa with no inflammation (Figures 2(a) and 2(b)).