case_images: PMC11319063_01
case_images: (A-D) Histomorphology of perigastric epithelioid GIST. (A, B) Low and higher power showing epithelioid tumor cells with focal perinuclear vacuoles, hematoxylin and eosin (H&E) stain. (C, D) DOG-1 and CD117/c-kit immunohistochemical stains are diffusely positive, supporting the diagnosis of GIST. Scale bars: (A) 100 mum; (B-D) 50 mum.
case_images: CRIONM2024-8684418.001.jpg
case_images: PMC11319063_01_CRIONM2024-8684418.001.jpg
case_images: fig1
case_images: A fine needle aspiration (FNA) was performed via endoscopic ultrasound (EUS), and final pathology reported GIST (Figures 1 and 2).
case_images: (A-D) Histomorphology of small bowel mesenteric desmoid-type fibromatosis. (A, B) Low and higher power showing fascicles of spindle cells with small nucleoli, H&E stain. (C) Beta-catenin immunohistochemical stain shows nuclear positivity, supporting the diagnosis of mesenteric desmoid-type fibromatosis. (D) DOG-1 immunohistochemical stain is negative. Scale bars: (A) 100 mum; (B-D) 50 mum.
case_images: CRIONM2024-8684418.002.jpg
case_images: PMC11319063_01_CRIONM2024-8684418.002.jpg
case_images: fig2
case_images: A fine needle aspiration (FNA) was performed via endoscopic ultrasound (EUS), and final pathology reported GIST (Figures 1 and 2).
case_images: Response to treatment. Imaging showing response to treatment from (a) June 2021 (baseline) to (b) June 2022 (after 9 months on avapritinib).
case_images: CRIONM2024-8684418.003.jpg
case_images: PMC11319063_01_CRIONM2024-8684418.003.jpg
case_images: fig3
case_images: Imaging after 9 months (Figure 3) showed that the ileal mass had significantly decreased to 3.7 x 4.5 cm; the patient underwent resection at that time.