case_images: PMC5818931_01
case_images: (a) Coronal view of noncontrast CT demonstrating left abdominal wall mass (arrow). (b) Axial view of noncontrast CT demonstrating left abdominal wall mass measuring approximately 7 cm x 5.5 cm (arrow).
case_images: CRIPA2018-1257284.001.jpg
case_images: PMC5818931_01_CRIPA2018-1257284.001.jpg
case_images: fig1
case_images: The patient subsequently underwent a noncontrast CT of abdomen and pelvis, which revealed a large abdominal mass measuring 7 cm x 5.5 cm abutting the mid portion of the transverse colon, with numerous metastatic foci in the liver, lymphadenopathy adjacent to the pancreatic head, a large lytic lesion involving the tenth rib, and scattered lytic areas throughout the spine and left iliac wing (Figure 1).
case_images: (a) 100x angiosarcoma H&E demonstrating tumor with high cellularity and prominent vascular network. (b) 400x angiosarcoma H&E demonstrating vasculature lined by plump, pleomorphic, endothelial cells. (c) 100x demonstrating CD31 positivity. (d) 100x demonstrating CD34 positivity.
case_images: CRIPA2018-1257284.002.jpg
case_images: PMC5818931_01_CRIPA2018-1257284.002.jpg
case_images: fig2
case_images: The liver biopsy delineated a very hypercellular specimen (Figure 2(a)). The tumor was comprised of a prominent vasoformative network (Figure 2(b)). Since the specimen stained for two vascular immunohistochemical stains (CD31 and CD34) in conjunction with pancytokeratin negativity, a diagnosis of angiosarcoma was rendered (Figures 2(c) and 2(d)).
case_images: (a) 400x Romanowsky stain demonstrating epithelioid cluster delineating vasoformative features. (b) 630x Romanowsky stain demonstrating vessel and plump hyperchromatic nuclei and intracytoplasmic lumen (arrow). (c) 100x angiosarcoma H&E demonstrating tumor consisting of anastamosing vascular channels and hobnailing nuclei. (d) 400x Romanowsky stain demonstrating malignant spindle cellular cluster.
case_images: CRIPA2018-1257284.003.jpg
case_images: PMC5818931_01_CRIPA2018-1257284.003.jpg
case_images: fig3
case_images: The cytology delineated a hypercellular aspirate (Figure 3).