case_images: PMC11800168_01
case_images: Verrucous squamous cell carcinoma of the gluteal region
case_images: cureus-0017-00000077059-i01.jpg
case_images: PMC11800168_01_cureus-0017-00000077059-i01.jpg
case_images: FIG1
case_images: At the first visit, the patient presented psoriasis of the knees, elbows, and scalp and gluteal tumor (Figure 1).
case_images: Verrucous exo- and endophytic growth of the epithelial tumor with expansive, demarcated growth and minimum cellular atypia. In the basal layer of the epidermis, there is an increased mitotic activity and the occasional occurrence of atypical mitotic figures. There are intraepithelial infiltrates consisting of polymorphonuclear cells forming intraepidermal abscesses. The dermis is involved in a chronic inflammatory infiltration with recent and older hemorrhagic lesions (H&E, magnification: 120x)
case_images: cureus-0017-00000077059-i02.jpg
case_images: PMC11800168_01_cureus-0017-00000077059-i02.jpg
case_images: FIG2
case_images: The biopsy from the tumor and inguinal lymph node histologically confirmed well-differentiated SCC (Figure 2) metastasizing to the inguinal lymph nodes with HPV type 6 and 16 positivity confirmed by real-time polymerase chain reaction (PCR).