case_images: PMC9636739_01
case_images: PMC9636739_02
case_images: macroscopic photo of the tumor occupying the hole gallbladder and invading the hepatic parenchyma, the cut section shows a heterogenous appearance with presence of many hemorrhagic and necrotic foci
case_images: PAMJ-42-284-g001.jpg
case_images: PMC9636739_02_PAMJ-42-284-g001.jpg
case_images: F1
case_images: Cut section of the mass showed a heterogenous appearance with many diffuse necrotic and hemorrhagic foci (Figure 1).
case_images: photomicroph of the carcinomatous component, made of irregular infiltrating tubes, made of markedly atypical large cells, HE; 100X
case_images: PAMJ-42-284-g002.jpg
case_images: PMC9636739_02_PAMJ-42-284-g002.jpg
case_images: F2
case_images: Microscopic examination showed a highly malignant neoplastic proliferation with two components: an epithelial, adenocarcinomatous component made of irregular infiltrating tubes, made of markedly atypical cells with large eosinophilic cytoplasm and large nuclei containing prominent nucleoli and showing frequent mitoses (Figure 2).
case_images: photomicrograph showing the sarcomatous component, made in this field of markedly atypical spindle cells, few tubes of the epithelial component can also be seen
case_images: PAMJ-42-284-g003.jpg
case_images: PMC9636739_02_PAMJ-42-284-g003.jpg
case_images: F3
case_images: Nuclei were hyperchromatic and many mitoses could be observed (Figure 3).
case_images: photomicrograph showing presence of cytoplasmic double striations, observed on the rhabdomyosarcomatous heterologous component of the sarcomatous component
case_images: PAMJ-42-284-g004.jpg
case_images: PMC9636739_02_PAMJ-42-284-g004.jpg
case_images: F4
case_images: These could be identified after use of the anti-desmin antibody (Figure 4).
case_images: (A,B) photomicrograph showing expression of CD31 (left) and CD34 (right) by cells layering the anastomosing channels
case_images: PAMJ-42-284-g005.jpg
case_images: PMC9636739_02_PAMJ-42-284-g005.jpg
case_images: F5
case_images: The vascular nature could be confirmed after identifying expression of CD31 and CD34 by neoplastic cells (Figure 5).