case_images: PMC10712981_01
case_images: Hematoxylin and eosin staining (magnification: x100) of core liver biopsy demonstrating scattered non-necrotizing granulomas (asterisks). The granulomas are centered around portal tract structures, but do not involve the bile ducts.
case_images: crg-2023-0017-0001-534818_F01.jpg
case_images: PMC10712981_01_crg-2023-0017-0001-534818_F01.jpg
case_images: F1
case_images: Core biopsies demonstrated well-formed, non-necrotizing granulomas centered around portal tracts, without involvement of the bile ducts (Fig. 1).
case_images: A scatter-line plot of the patient's clinical course, showing trends of alkaline phosphatase (ALP), alanine aminotransferase (ALT), and total bilirubin over time. Prednisone was administered in a 6-week taper, with 60 mg given initially and then reduced by 10 mg each week thereafter. Dapsone (100 mg) was held on the day of admission (week 0 on the graph) when liver injury was first noted.
case_images: crg-2023-0017-0001-534818_F02.jpg
case_images: PMC10712981_01_crg-2023-0017-0001-534818_F02.jpg
case_images: F2
case_images: Her clinical course is summarized in Figure 2.