case_images: PMC6204171_01
case_images: (a) H&E shows infiltrate of small lymphocytes x50. (b) Immunohistochemistry of CD20 highlighting the lymphocytes x50.
case_images: CRIHEM2018-3270348.001.jpg
case_images: PMC6204171_01_CRIHEM2018-3270348.001.jpg
case_images: fig1
case_images: Bone marrow biopsy revealed hypercellularity with diffuse infiltrate of the medium to large-sized mononuclear cells with irregular nuclear contours and prominent nucleoli similar to that seen in the peripheral blood smear (Figure 1).
case_images: CSF flow cytometry.
case_images: CRIHEM2018-3270348.002.jpg
case_images: PMC6204171_01_CRIHEM2018-3270348.002.jpg
case_images: fig2
case_images: Repeat CSF studies at our hospital showed lymphocytes accounting for 49% of total events per flow cytometry, positive for CD19, CD20, CD5, and CD23, with lambda light chain restriction, and negative for CD10 and FMC-7 (Figure 2).