case_images: PMC11067942_01
case_images: Multiple subcutaneous lesions over different locations. (A and B) lesions in both elbows. (C) lesions in both knees. (D) lesions in buttocks. (E) lesions in Achilles tendons. (F) lesions over proximal interphalangeal joints.
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case_images: The masses were of varying sizes, ranging from 0.3 cm to 8 cm (Figure 1).
case_images: MRI imaging of xanthomas masses on left (A and B) and right (C and D) elbows. The masses revealed low signal intensity on T1-weighted images and low-high mixed signal intensity on T2-weighted images.
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case_images: The masses revealed low signal intensity on T1-weighted images and low-high mixed signal intensity on T2-weighted images. (Figure 2).
case_images: Intraoperative photograph of the lesions. (A and B) Resected xanthomas. (C) The sectional view of the xanthomas.
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case_images: The cores of masses were yellowish-colored, relatively soft, no necrosis, and confined to the subcutaneous tissue without involving underlying muscle or joint capsule (Figure 3).
case_images: Pathological pictures of the lesion. (A) Hematoxylin/eosin analysis showed infiltration of foamy cells and scattered giant cells (x200). CD68-immunostaining (B), Ki67- immunostaining (C) and TFE3- immunostaining (D) of the xanthomas presented positive (x200).
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case_images: Histopathology showed infiltration of foam cells and scattered giant cells with lipid-rich background (Figure 4).
case_images: Status of the incisions two days after the operation. (A and B) elbows. (C) buttocks. (D) knees.
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case_images: After removal, all incisions were sutured carefully (Figure 5).