case_images: PMC3929053_01
case_images: (a) Normal X-ray chest (b) X-ray left lower limb showing radiolucent mass in the mid shaft with extensive calcification (c and d) MRI scan showing well defined lobulated mass with infiltration in the medullary cavity
case_images: ABR-3-33-g001.jpg
case_images: PMC3929053_01_ABR-3-33-g001.jpg
case_images: F1
case_images: X-ray was normal [Figure 1a]. X-ray of the affected lower limb revealed large lucent defect in the medullary cavity in the mid shaft, with extensive calcification/ossification in the soft tissue mass [Figure 1b]. Magnetic resonance imaging (MRI) scan revealed a well defined lobulated mass with infiltration in the medullary cavity suggestive of a malignant neoplastic lesion, possibly osteosarcoma [Figure 1c and d].
case_images: Photomicrograph showing (a) Malignant spindle shaped cells (b) Osteoid with pleomorphic cells (c) Large areas of hemorrhage with endothelial lined vascular areas and neoplastic cells (d) Chondroblastic areas (H&E, x100)
case_images: ABR-3-33-g002.jpg
case_images: PMC3929053_01_ABR-3-33-g002.jpg
case_images: F2
case_images: Areas with islands of malignant round cells were also seen [Figures 2 and 3].
case_images: Photomicrograph showing (a) Vascular spaces arranged in stag horn pattern and spindle shaped cell arranged around it in hemangiopericytomatous pattern (H&E, x100) (b) Osteoid with large pleomorphic cells (H&E, x400) (c) Malignant small round cell pattern (H&E, x400) (d) Fibroblastic areas (H&E, x400)
case_images: ABR-3-33-g003.jpg
case_images: PMC3929053_01_ABR-3-33-g003.jpg
case_images: F3
case_images: Areas with islands of malignant round cells were also seen [Figures 2 and 3].