case_images: PMC10955628_01
case_images: Clinical courses illustrating thrombocytopenia and main treatments. BM, Bone marrow.
case_images: fonc-14-1353896-g001.jpg
case_images: PMC10955628_01_fonc-14-1353896-g001.jpg
case_images: f1
case_images: On April, the patient suffered from severe thrombocytopenia and was referred to our hospital ( Figure 1 ).
case_images: Bone marrow trephine biopsy. (A) Normocellular marrow (H&E, X5); (B) Absence of megacaryocytes and normal maturation pattern of erythroid and myeloid cells (H&E, X20). (C) Immunohistochemical staining with anti-CD61 confirms the absence of megacaryocytes (anti-CD61, x15). (D) Moderate neactive CD8+ T infiltrate (anti-CD8, x15).
case_images: fonc-14-1353896-g002.jpg
case_images: PMC10955628_01_fonc-14-1353896-g002.jpg
case_images: f2
case_images: T-CD8+ lymphocyte infiltration (negative clonal T-cell population assessment). There was no evidence of myelodysplastic neoplasia, myelofibrosis, or metastatic lesions ( Figure 2 ).