case_images: PMC9381253_01
case_images: (a) Ulcerated and necrotic right nasolabial plaque with destruction of the right nasal wing on day 1 of the consultation. (b) Ulcerated and necrotic nasolabial plaque with significant loss of substance one month later after the first day of consultation.
case_images: CRIDM2022-5672783.001.jpg
case_images: PMC9381253_01_CRIDM2022-5672783.001.jpg
case_images: fig1
case_images: The lesion was infiltrated at the base with ulceration in its center and destruction of the right wing of the nose (Figure 1).
case_images: (a) Diffuse lymphoid infiltrate of the dermis and hypodermis epidermotropism, (b) diffuse lymphoid infiltrate of the dermis and hypodermis epidermotropism.
case_images: CRIDM2022-5672783.002.jpg
case_images: PMC9381253_01_CRIDM2022-5672783.002.jpg
case_images: fig2
case_images: The cells were of medium size with reduced cytoplasm and rounded or cleaved nuclei with 6 mitoses/10 HPF (Figure 2).
case_images: Immunohistochemistry had shown a lymphoid infiltrate expressing (a) CD3 +: positive, (b) CD8 + positive, and (c) KI67: proliferative index estimated at 50%.
case_images: CRIDM2022-5672783.003.jpg
case_images: PMC9381253_01_CRIDM2022-5672783.003.jpg
case_images: fig3
case_images: Ki67, a proliferative index, was estimated at 50% (Figure 3).
case_images: Complete healing of the lesion three months after the last chemotherapy treatment.
case_images: CRIDM2022-5672783.004.jpg
case_images: PMC9381253_01_CRIDM2022-5672783.004.jpg
case_images: fig4
case_images: After three doses of multidrug therapy, the lesion was completely healed (Figure 4).