case_images: PMC10985165_01
case_images: Results of Wright's stain. Wright's stain showed the marrow morphology.
case_images: fonc-14-1341840-g001.jpg
case_images: PMC10985165_01_fonc-14-1341840-g001.jpg
case_images: f1
case_images: No other special cells were observed ( Figure 1 ).
case_images: Results of peroxidase POX staining. Peroxidase POX staining showed the marrow morphology which indicated the AML-M3 with atypical morphology.
case_images: fonc-14-1341840-g002.jpg
case_images: PMC10985165_01_fonc-14-1341840-g002.jpg
case_images: f2
case_images: Homeochemical staining of peroxidase POX (+ ~ + +) ( Figure 2 ).
case_images: Results of flow cytometry test of the blood samples. (A) The detection of CD34, CD177, HLA-DR, CD33, CD13, CD11b, CD64. (B) The detection of CD20 + 2, CD15, CD19, CD5, CD79a, CD56.
case_images: fonc-14-1341840-g003.jpg
case_images: PMC10985165_01_fonc-14-1341840-g003.jpg
case_images: f3
case_images: Abnormal myeloid cells were observed, accounting for 85.62% of the nuclear cells, expressing CD9 and MPO, heterogeneous expressing CD13, and not expressing HLA-DR. AML was considered, and AML with PML/RARa could not be excluded ( Figure 3 ). (In this case, SSC was small, non-specific fluorescence was not obvious, and some cells were CD34 positive, so APL of fine or less granule should be excluded.)
case_images: Results of marrow karyotype analysis. Karyotype analysis showed the clonal abnormalities add (8p), t (15; 17).
case_images: fonc-14-1341840-g004.jpg
case_images: PMC10985165_01_fonc-14-1341840-g004.jpg
case_images: f4