case_images: PMC4208430_01
case_images: A case of combined HCC (brown cut surface) and FLC (lobulated grey white cut surface):right hepatectomy specimen.
case_images: CRIHEP2013-101862.001.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.001.jpg
case_images: fig1
case_images: Adjoining this tumor was another nodular lesion measuring 8 x 9 x 9 cm with lobulated grey white cut surface (Figure 1).
case_images: HCC showing tumor cells arranged in pseudoglandular and trabecular pattern, hematoxylin-eosin 200x.
case_images: CRIHEP2013-101862.002.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.002.jpg
case_images: fig2
case_images: Microscopic examination of the larger brown tumor and the small nodules showed large polygonal cells arranged in pseudoglandular and trabecular pattern (Figure 2) separated by sinusoidal vascular channels.
case_images: Fibrolamellar carcinoma showing tumor cells with abundant eosinophilic cytoplasm separated by lamellar bands of hyalinised collagen, hematoxylin-eosin 100x.
case_images: CRIHEP2013-101862.003.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.003.jpg
case_images: fig3
case_images: Sections from the grey white mass showed a tumor with a fibrolamellar pattern composed of trabeculae of large polygonal cells separated by lamellar bands of hyalinized collagen (Figure 3).
case_images: Tumor cells showing diffuse granular cytoplasmic positivity for Hep-par 1 in HCC, immunohistochemistry 200x.
case_images: CRIHEP2013-101862.004.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.004.jpg
case_images: fig4
case_images: Immunohistochemistry revealed tumor cells of HCC with diffuse positivity for Hep Par1 (Figure 4) and focal positivity for CK7 (Figure 5) whereas the tumor cells of fibrolamellar-type showed diffuse strong positivity for CK7 (Figure 6).
case_images: Tumor cells of HCC showing focal positivity for CK7, immunohistochemistry 100x.
case_images: CRIHEP2013-101862.005.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.005.jpg
case_images: fig5
case_images: Immunohistochemistry revealed tumor cells of HCC with diffuse positivity for Hep Par1 (Figure 4) and focal positivity for CK7 (Figure 5) whereas the tumor cells of fibrolamellar-type showed diffuse strong positivity for CK7 (Figure 6).
case_images: Tumor cells of FLC showing diffuse positivity for CK7, immunohistochemistry 100x.
case_images: CRIHEP2013-101862.006.jpg
case_images: PMC4208430_01_CRIHEP2013-101862.006.jpg
case_images: fig6
case_images: Immunohistochemistry revealed tumor cells of HCC with diffuse positivity for Hep Par1 (Figure 4) and focal positivity for CK7 (Figure 5) whereas the tumor cells of fibrolamellar-type showed diffuse strong positivity for CK7 (Figure 6).