case_images: PMC7334388_01
case_images: Gross photographs of the lobectomy specimen showing (a) sequential slices from superior to inferior and (b) a closer view of the tan, fleshy, and nodular appearance of the tumor.
case_images: gr1.jpg
case_images: PMC7334388_01_gr1.jpg
case_images: fig0005
case_images: Gross examination (Fig. 1) revealed a 53 g thyroid lobe measuring 6.3 x 5.2 x 4.0 cm, containing a 5.8 cm tumor extending to the inked capsule.
case_images: (a) Photomicrograph demonstrating adjacent lymphocytic thyroiditis (hematoxylin and eosin; magnification 100x). (b) Low-power (hematoxylin and eosin; magnification 200x) and high-power (inset; hematoxylin and eosin; magnification 1000x oil immersion) photomicrographs of FL and (c) low-power (hematoxylin and eosin; magnification 200x) and high-power (inset; hematoxylin and eosin; magnification 1000x oil immersion) photomicrographs of DLBCL.
case_images: gr2.jpg
case_images: PMC7334388_01_gr2.jpg
case_images: fig0010
case_images: Microscopic evaluation (Fig. 2) showed diffuse infiltrates of large pleomorphic cells, and areas with nodular infiltrate of small sized cells with irregular nuclei.
case_images: (a) Photomicrograph showing FL (arrowhead) and DLBCL (arrow) replacing normal thyroid parenchyma (hematoxylin and eosin; magnification 200x). (b) Ki-67 proliferation index is approximately 20% in the areas involved by FL and 90% in the areas involved by DLBCL (magnification 200x). The neoplastic B-cells are positive for (c) CD20 (magnification 200x) and (d) CD10 (magnification 200x).
case_images: gr3.jpg
case_images: PMC7334388_01_gr3.jpg
case_images: fig0015
case_images: Immunohistochemistry (IHC, Fig. 3), revealed CD20 + B cells which co-expressed CD10, BCL6 and BCL2, but not cyclin 1.