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case_images: Erythema, papules, scales and excoriation on the waist.
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case_images: Upon dermatological examination, erythema, papules, scales, and excoriation were observed on her shoulders and waist (Figure 1).
case_images: Psoriasis- like lesions: demarcated scaly erythematous lesions.
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case_images: However, the erythema and papules on her waist had evolved into well-demarcated scaly erythematous lesions (Figure 2).
case_images: Histopathology showed psoriasiform acanthosis with a diminished granular layer, lymphocyte infiltration in the superficial dermis. (HE stain, magnification 4*10).
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case_images: A 3-mm puncture biopsy was performed in this area, and histopathology revealed psoriasiform acanthosis with a diminished granular layer and lymphocyte infiltration in the superficial dermis, suggesting the development of dupilumab-induced psoriasiform dermatitis (Figure 3).
case_images: Topical calcipotriol and betamethasone ointment was applied to the psoriasis-like lesions.
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case_images: This local treatment improved the skin lesions (Figure 4), but the pruritus remained significant, affecting her sleep.
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case_images: (A-D) Erythema, papules, scales on the shoulder (A), back (B), lower limbs (C) and popliteal fossa (D).
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case_images: Dermatological examination revealed erythema, papules, and scales on the limbs and back of the patient (Figure 5A-D).