case_images: PMC10673345_01
case_images: Computed tomography (CT) images. a A chest plane CT image taken on the 17th day after PEG-G-CSF administration. This image does not show an increased soft periaortic shadow. b A chest contrast-enhanced (CE)-CT scan obtained on the 18th day of PEG-G-CSF administration. This image shows an increased soft periaortic shadow suggestive of aortitis. c The chest CE-CT scan performed on the 33rd day of PEG-G-CSF administration. As indicated by the red triangle in the figures, the periaortic soft shadow shrunk compared with that shown in b.
case_images: cro-2023-0016-0001-534931_F01.jpg
case_images: PMC10673345_01_cro-2023-0016-0001-534931_F01.jpg
case_images: F1
case_images: However, physical examination and simple CT of the entire trunk and head failed to detect the source of the fever or cause of the elevated inflammatory response (Fig. 1a). CE-CT of the entire trunk performed the next day showed increased adipose tissue density around the descending thoracic aorta from the aortic arch, suggesting aortitis (Fig. 1b). On the 20th day, the patient's body temperature improved to 36 C, right ear pain and inflammatory response gradually improved, and contrast CT on the 33rd day showed improvement in periaortic inflammatory findings (Fig. 1c, 2).
case_images: Line graph of trends in white blood cell (WBC) counts and C-reactive protein (CRP). The blue line indicates the trend in CRP levels, and the red line indicates the trend in WBC counts. Both CRP level and WBC count were abnormally high on the 17th day after PEG-G-CSF administration. However, they continued to decrease without corticosteroid administration and were almost normalized on the 33rd day of PEG-G-CSF administration.
case_images: cro-2023-0016-0001-534931_F02.jpg
case_images: PMC10673345_01_cro-2023-0016-0001-534931_F02.jpg
case_images: F2
case_images: On the 20th day, the patient's body temperature improved to 36 C, right ear pain and inflammatory response gradually improved, and contrast CT on the 33rd day showed improvement in periaortic inflammatory findings (Fig. 1c, 2).