case_images: PMC11609880_01
case_images: Abdominal imaging studies. (A) Abdominal CT scan upon first presentation, illustrating mid-abdomen collection. (B) Abdominal CT scan upon first presentation, illustrating liver lesions. (C) Abdominal MRI 1 month later, demonstrating worsened liver lesions. (D) Hematoxylin and eosin staining of biopsy sample (magnification, x20). (E) Hematoxylin and eosin stain of biopsy sample (magnification, x40). (F) beta-hCG staining of biopsy sample. Red arrows in panels B and C indicate liver lesions; black arrows in panel F indicate some of the beta-hCG-positive cells. beta-hCG, free beta subunit of human chorionic gonadotropin.
case_images: mi-05-01-00207-g00.jpg
case_images: PMC11609880_01_mi-05-01-00207-g00.jpg
case_images: f1-MI-5-1-00207
case_images: An abdominal computed Tomography (CT) scan revealed an ill-defined collection in the mid-abdomen, measuring up to 6 cm, with adjacent thickened loops of the small bowel, as well as the sigmoid colon (Fig. 1A) and hypodense lesions in the liver (Fig. 1B). This revealed more severe multiple hepatic lesions (Fig. 1C). An endoscopic biopsy revealed poorly differentiated adenocarcinoma (Fig. 1D and E), with the immunohistochemistry stains consistent with colonic adenocarcinoma (data not shown).
case_images: Graph depicting the key events and changes in beta-hCG levels in the patient over time. beta-hCG, free beta subunit of human chorionic gonadotropin; mFOLFOX6, 5-fluorouracil, leucovorin, and oxaliplatin; MTX, methotrexate; TAUS, transabdominal ultrasound; TVUS, transvaginal ultrasound; D&C, dilation and curettage.
case_images: mi-05-01-00207-g01.jpg
case_images: PMC11609880_01_mi-05-01-00207-g01.jpg
case_images: f2-MI-5-1-00207
case_images: The trend of serum beta-hCG levels and key events of the patient are summarized in Fig. 2.