case_images: PMC6458917_01
case_images: Mammography demonstrates a stable oval, circumscribed mass in the medial part of the left breast.
case_images: CRIPA2019-6098747.001.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.001.jpg
case_images: fig1
case_images: In mammography, a radiologic circumscribed, well-demarcated density, of her medial left breast without lymph node enlargement, was identified (Figure 1).
case_images: Macroscopic appearance of a well circumscribed, solid with subtle nodularity tumor, with central areas of necrosis.
case_images: CRIPA2019-6098747.002.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.002.jpg
case_images: fig2
case_images: On gross examination, serial sectioning revealed a large solid, well circumscribed, lobulated, with subtle nodularity tumor, measuring 4,8X4X3,8cm, with central necrosis (Figure 2).
case_images: Histological appearance of infiltrative lesion (on the right) of the breast (on the left) composed of sheets of small round blue cells (Hematoxylin & eosin, original magnification X50).
case_images: CRIPA2019-6098747.003.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.003.jpg
case_images: fig3
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Histological examination shows solid infiltration of small/intermediate neoplastic cells displaying round hyperchromatic pleomorphic nuclei with indistinct cytoplasm and brisk mitotic activity (Hematoxylin & eosin, original magnification X200).
case_images: CRIPA2019-6098747.004.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.004.jpg
case_images: fig4
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Same as Figure 4, higher magnification.
case_images: CRIPA2019-6098747.005.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.005.jpg
case_images: fig5
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Tumor cells grow in nests separated by hyalinized fibrous septa (X200, H&E stain).
case_images: CRIPA2019-6098747.006.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.006.jpg
case_images: fig6
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Tumor cells with extensive necrosis (H&E, X200).
case_images: CRIPA2019-6098747.007.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.007.jpg
case_images: fig7
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Alveolar pattern with necrosis (H&E, X200).
case_images: CRIPA2019-6098747.008.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.008.jpg
case_images: fig8
case_images: The final histopathological report showed an undifferentiated, high grade tumor of the "small round blue cell" morphology, suggestive of rhabdomyosarcoma (Figures 3-8).
case_images: Immunohistochemistry shows positive cytoplasmic (dot-like) staining of the tumor cells for desmin (X200).
case_images: CRIPA2019-6098747.009.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.009.jpg
case_images: fig9
case_images: Staining for desmin (Figure 9), myogenin (Figure 10), myoD1 (Figure 11), NF (Figure 12), and bcl-2 (Figure 13) confirmed the diagnosis of RMS (solid variant of alveolar type).
case_images: Immunohistochemistry shows positive nuclear staining of the tumor cells for myogenin (X100).
case_images: CRIPA2019-6098747.010.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.010.jpg
case_images: fig10
case_images: Staining for desmin (Figure 9), myogenin (Figure 10), myoD1 (Figure 11), NF (Figure 12), and bcl-2 (Figure 13) confirmed the diagnosis of RMS (solid variant of alveolar type).
case_images: Immunohistochemistry shows positive nuclear staining of the tumor cells for myo-D1 (X200).
case_images: CRIPA2019-6098747.011.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.011.jpg
case_images: fig11
case_images: Staining for desmin (Figure 9), myogenin (Figure 10), myoD1 (Figure 11), NF (Figure 12), and bcl-2 (Figure 13) confirmed the diagnosis of RMS (solid variant of alveolar type).
case_images: Immunohistochemistry shows positive cytoplasmic (dot-like) staining of the tumor cells for neurofilament (NF) (X100).
case_images: CRIPA2019-6098747.012.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.012.jpg
case_images: fig12
case_images: Staining for desmin (Figure 9), myogenin (Figure 10), myoD1 (Figure 11), NF (Figure 12), and bcl-2 (Figure 13) confirmed the diagnosis of RMS (solid variant of alveolar type).
case_images: Immunohistochemistry shows positive cytoplasmic staining of the tumor cells for bcl-2 (X400).
case_images: CRIPA2019-6098747.013.jpg
case_images: PMC6458917_01_CRIPA2019-6098747.013.jpg
case_images: fig13
case_images: Staining for desmin (Figure 9), myogenin (Figure 10), myoD1 (Figure 11), NF (Figure 12), and bcl-2 (Figure 13) confirmed the diagnosis of RMS (solid variant of alveolar type).