case_images: PMC10948227_01
case_images: Clinical case #1. The lesion developed on a buccal aspect between teeth #8 and 9 with no apparent radiographic changes (a-e). The lesion was excised using a scalpel blade (f-h). Postoperative healing at 1 week revealed no complications (i-k). The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (l, m) were submitted for histological analysis to institutional oral pathology facilities, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (n, o).
case_images: CRID2024-3683561.001.jpg
case_images: PMC10948227_04_CRID2024-3683561.001.jpg
case_images: fig1
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully (Figures 1(i)-1(k)). The excised lesion (~12.5 x 10 x 7.5 mm, Figures 1(l) and 1(m)) was placed in 10% neutral buffered formalin immediately after harvesting it during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thickness) and stained with hematoxylin and eosin (Figures 1(n) and 1(o)).
case_images: PMC10948227_02
case_images: PMC10948227_03
case_images: Clinical case #1. The lesion developed on a buccal aspect between teeth #8 and 9 with no apparent radiographic changes (a-e). The lesion was excised using a scalpel blade (f-h). Postoperative healing at 1 week revealed no complications (i-k). The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (l, m) were submitted for histological analysis to institutional oral pathology facilities, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (n, o).
case_images: CRID2024-3683561.001.jpg
case_images: PMC10948227_04_CRID2024-3683561.001.jpg
case_images: fig1
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully (Figures 1(i)-1(k)). The excised lesion (~12.5 x 10 x 7.5 mm, Figures 1(l) and 1(m)) was placed in 10% neutral buffered formalin immediately after harvesting it during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thickness) and stained with hematoxylin and eosin (Figures 1(n) and 1(o)).
case_images: PMC10948227_04
case_images: Clinical case #1. The lesion developed on a buccal aspect between teeth #8 and 9 with no apparent radiographic changes (a-e). The lesion was excised using a scalpel blade (f-h). Postoperative healing at 1 week revealed no complications (i-k). The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (l, m) were submitted for histological analysis to institutional oral pathology facilities, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (n, o).
case_images: CRID2024-3683561.001.jpg
case_images: PMC10948227_04_CRID2024-3683561.001.jpg
case_images: fig1
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully (Figures 1(i)-1(k)). The excised lesion (~12.5 x 10 x 7.5 mm, Figures 1(l) and 1(m)) was placed in 10% neutral buffered formalin immediately after harvesting it during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thickness) and stained with hematoxylin and eosin (Figures 1(n) and 1(o)).
case_images: PMC10948227_05
case_images: Clinical case #2. The lesion developed on a palatal aspect between teeth #8 and 9 with no apparent radiographic changes (a-d). The lesion was excised using a scalpel blade (e-g). Postoperative healing at 1-week (h), one-month (i), and three-month (j) follow-up appointments was found to be uneventful. Tissue samples harvested during biopsy (k, l) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (m, n).
case_images: CRID2024-3683561.002.jpg
case_images: PMC10948227_08_CRID2024-3683561.002.jpg
case_images: fig2
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully as shown in Figure 2(h). Healing continued to be uneventful at one-month (Figure 2(i)) and three-month (Figure 2(j)) follow-up appointments. The excised lesion (~12 x 9 x 5 mm, Figures 2(k) and (l)) was placed in 10% neutral buffered formalin immediately after harvesting during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 2(m) and 2(n)).
case_images: PMC10948227_06
case_images: PMC10948227_07
case_images: Clinical case #2. The lesion developed on a palatal aspect between teeth #8 and 9 with no apparent radiographic changes (a-d). The lesion was excised using a scalpel blade (e-g). Postoperative healing at 1-week (h), one-month (i), and three-month (j) follow-up appointments was found to be uneventful. Tissue samples harvested during biopsy (k, l) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (m, n).
case_images: CRID2024-3683561.002.jpg
case_images: PMC10948227_08_CRID2024-3683561.002.jpg
case_images: fig2
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully as shown in Figure 2(h). Healing continued to be uneventful at one-month (Figure 2(i)) and three-month (Figure 2(j)) follow-up appointments. The excised lesion (~12 x 9 x 5 mm, Figures 2(k) and (l)) was placed in 10% neutral buffered formalin immediately after harvesting during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 2(m) and 2(n)).
case_images: PMC10948227_08
case_images: Clinical case #2. The lesion developed on a palatal aspect between teeth #8 and 9 with no apparent radiographic changes (a-d). The lesion was excised using a scalpel blade (e-g). Postoperative healing at 1-week (h), one-month (i), and three-month (j) follow-up appointments was found to be uneventful. Tissue samples harvested during biopsy (k, l) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (m, n).
case_images: CRID2024-3683561.002.jpg
case_images: PMC10948227_08_CRID2024-3683561.002.jpg
case_images: fig2
case_images: One week after the surgery, the gingival tissue in the surgical area appeared to heal uneventfully as shown in Figure 2(h). Healing continued to be uneventful at one-month (Figure 2(i)) and three-month (Figure 2(j)) follow-up appointments. The excised lesion (~12 x 9 x 5 mm, Figures 2(k) and (l)) was placed in 10% neutral buffered formalin immediately after harvesting during the surgery and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 2(m) and 2(n)).
case_images: PMC10948227_09
case_images: PMC10948227_10
case_images: Clinical case #3. The lesion developed on a buccal aspect between teeth #27 and 28 with no apparent radiographic changes (a-d). The lesion was excised using the Biolase laser (940 nm wavelength) equipped with a 300 mum tip and at an average power of 1 W (e-k). Postoperative healing at 1 week (l, m), 2 weeks (n), 4 weeks (o), and 6 weeks (p, q) revealed uneventful healing with no complications. The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (r, s) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (t, u).
case_images: CRID2024-3683561.003.jpg
case_images: PMC10948227_13_CRID2024-3683561.003.jpg
case_images: fig3
case_images: One week after the surgery, Coe-Pak  was removed, teeth were scaled and polished, and the gingival tissue in the surgical area appeared to heal uneventfully (Figures 3(l) and 3(m)). Moderate edema and erythema with no signs of bleeding and suppuration were observed at 2 weeks (Figure 3(n)), 4 weeks (Figure 3(o)), and 6 weeks (Figures 3(p) and 3(q)). The excised lesion (~8 x 11 x 4 mm, Figures 3(r) and 3(s)) was placed in 10% neutral buffered formalin immediately after harvesting and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 3(t) and 3(u)).
case_images: PMC10948227_11
case_images: PMC10948227_12
case_images: Clinical case #3. The lesion developed on a buccal aspect between teeth #27 and 28 with no apparent radiographic changes (a-d). The lesion was excised using the Biolase laser (940 nm wavelength) equipped with a 300 mum tip and at an average power of 1 W (e-k). Postoperative healing at 1 week (l, m), 2 weeks (n), 4 weeks (o), and 6 weeks (p, q) revealed uneventful healing with no complications. The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (r, s) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (t, u).
case_images: CRID2024-3683561.003.jpg
case_images: PMC10948227_13_CRID2024-3683561.003.jpg
case_images: fig3
case_images: One week after the surgery, Coe-Pak  was removed, teeth were scaled and polished, and the gingival tissue in the surgical area appeared to heal uneventfully (Figures 3(l) and 3(m)). Moderate edema and erythema with no signs of bleeding and suppuration were observed at 2 weeks (Figure 3(n)), 4 weeks (Figure 3(o)), and 6 weeks (Figures 3(p) and 3(q)). The excised lesion (~8 x 11 x 4 mm, Figures 3(r) and 3(s)) was placed in 10% neutral buffered formalin immediately after harvesting and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 3(t) and 3(u)).
case_images: PMC10948227_13
case_images: Clinical case #3. The lesion developed on a buccal aspect between teeth #27 and 28 with no apparent radiographic changes (a-d). The lesion was excised using the Biolase laser (940 nm wavelength) equipped with a 300 mum tip and at an average power of 1 W (e-k). Postoperative healing at 1 week (l, m), 2 weeks (n), 4 weeks (o), and 6 weeks (p, q) revealed uneventful healing with no complications. The patient did not present for further follow-up appointments. Tissue samples harvested during biopsy (r, s) were submitted for histological analysis, and histopathologic findings were found to be pathognomonic in the diagnosis of POF (t, u).
case_images: CRID2024-3683561.003.jpg
case_images: PMC10948227_13_CRID2024-3683561.003.jpg
case_images: fig3
case_images: One week after the surgery, Coe-Pak  was removed, teeth were scaled and polished, and the gingival tissue in the surgical area appeared to heal uneventfully (Figures 3(l) and 3(m)). Moderate edema and erythema with no signs of bleeding and suppuration were observed at 2 weeks (Figure 3(n)), 4 weeks (Figure 3(o)), and 6 weeks (Figures 3(p) and 3(q)). The excised lesion (~8 x 11 x 4 mm, Figures 3(r) and 3(s)) was placed in 10% neutral buffered formalin immediately after harvesting and submitted for histological analysis. The decalcified tissue was sectioned using a soft tissue microtome (3 mum thick sections) and stained with hematoxylin and eosin (Figures 3(t) and 3(u)).