case_images: PMC4357675_01
case_images: Exophytic nodular lesion approximately 3 x 6 cm in size with surface ulceration in the left lateral perianal region.
case_images: cde-0007-0025-g01.jpg
case_images: PMC4357675_01_cde-0007-0025-g01.jpg
case_images: F1
case_images: Dermatology examination revealed an exophytic condyloma-like nodular lesion approximately 3 x 6 cm in size with surface ulceration in the left lateral perianal region and no other pathological findings on whole body examination (fig. 1).
case_images: a Edematous stroma, mononuclear inflammatory cells, stratified squamous epithelium with epithelial cell islands containing pleomorphic cells and showing infiltrative growth and tumor cell islands with peripheral palisading. HE, x40. b The tumor islands with peripheral palisading. The tumor cells had a pleomorphic character with a large vesicular nucleus and narrow cytoplasm. HE, x400.
case_images: cde-0007-0025-g02.jpg
case_images: PMC4357675_01_cde-0007-0025-g02.jpg
case_images: F2
case_images: HIV, HSV and syphilis serology results were negative. Histopathological evaluation of a punch biopsy obtained from the lesion showed an edematous stroma containing mononuclear inflammatory cells under a stratified squamous epithelium with epithelial cell islands containing pleomorphic cells and showing infiltrative growth and tumor cell islands with peripheral palisading (fig. 2a). The tumor cells had a pleomorphic character, with a large vesicular nucleus and narrow cytoplasm (fig. 2b).