case_images: PMC1242220_01
case_images: Histopathological findings on hard palate biopsy showing diffuse chorion infiltration by a poorly differentiated carcinoma with a focal microglandular growth pattern (hematoxylin and eosin stain, x400).
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case_images: PMC1242220_01_1471-2407-5-117-1.jpg
case_images: F1
case_images: One month later, a second hard palate biopsy revealed an undifferentiated carcinoma with a focal microglandular and diffuse signet-ring cell growth infiltrating the subepithelial chorion mucosa consistent with a gastric origin (Fig. 1).
case_images: Gastric biopsies revealed an undifferentiated signet-ring cell gastric carcinoma (hematoxylin and eosin stain, x400). Note the characteristic distribution of blue intracytoplasmic mucines in the neoplastic cells (inset) (Alcian-Pas stain, x400).
case_images: 1471-2407-5-117-2.jpg
case_images: PMC1242220_01_1471-2407-5-117-2.jpg
case_images: F2
case_images: Although the patient was asymptomatic, gastroscopy showed an ulcerated lesion of the greater curvature of the stomach, and histopathogy revealed an undifferentiated gastric carcinoma with signet-ring cells (Fig. 2).
case_images: Clinical photograph of the hard palate lesion after biopsy.
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case_images: F3
case_images: She was admitted to our Institution in October 2003, when a physical examination revealed left supraclavicular adenopathy, left exophthalmus, and a firm and painless erythematous mass of nearly 4 cm on her left hard palate, with no evidence of bleeding at palpation (Fig. 3).
case_images: Magnetic resonance image of the maxilla showing an enhanced lesion of the left hard palate with thickening of the genal mucosa and no bone involvement.
case_images: 1471-2407-5-117-4.jpg
case_images: PMC1242220_01_1471-2407-5-117-4.jpg
case_images: F4
case_images: The results of chest and abdominal CT scans were negative, but magnetic resonance imaging of the maxilla revealed an enhanced 2.7 x 2.3 cm lesion on the left hard palate, with thickening of the genal mucosa and no bone involvement (Fig. 4).