case_images: PMC8371466_01
case_images: Chronic inflammation and immune activation: a delicate balance.
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case_images: f1
case_images: As known, inflammation plays a key role in oncogenesis (Figure 1).
case_images: The pathogenetic role of HIV.
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case_images: f2
case_images: Moreover, HIV could determine microsatellite gene instability and genetic alterations, promoting formation of different cancers, including NMSCs (Figure 2).
case_images: The exploration of a bond between NMSCs and immuno-viral profile of PLWH.
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case_images: f3
case_images: A peculiar correlation between decreased immune-surveillance and carcinogenic virus co-infections might favor oncogenesis, increasing the risk of developing tumors in these subjects (see Figure 3).