case_images: PMC11401011_01
case_images: Echocardiography (RV: Right Ventricle, LV: Left Ventricle, RA: Right Atrium, LA: Left Atrium). (A and B) At admission, the heart tumor was 72 x 43 mm in size and adhered to the right atrial wall, tricuspid valve, and right ventricular wall, causing severe stenosis of the tricuspid valve and loss of nearly all function, with little pericardial fluid. There were no signs of cardiac tamponade. (C) After 3 weeks of treatment, the tumor size was 57.6 x 16.9 mm, partially obstructing the flow of the tricuspid valve. There was no pericardial fluid. (D) After 10 weeks of treatment, the tumor size was 23.8 x 19.1 mm, and the tricuspid valve functioned normally. There was no pericardial fluid.
case_images: 10.1177_11795476241277663-fig1.jpg
case_images: PMC11401011_04_10.1177_11795476241277663-fig1.jpg
case_images: fig1-11795476241277663
case_images: Echocardiogram before 5th cycle chemotherapy showed that the tumor size in the right heart chamber had decreased to 23.8 x 19.1 mm, the tricuspid valve was working well, and there was no pericardial fluid (Figure 1D).
case_images: Chest computed tomography. (A) Computed tomography scan upon admission: large tumor located in both right atrium and ventricle, with the size of 69.3 x 48.7 mm, obstructing blood flow through the tricuspid valve, causing the right atrium to dilate. The right pleural effusion was large, with a fluid thickness of 46.9 mm. The mediastinal tumor was located just below the carina, compressing and causing narrowing of the right pulmonary artery. (B) Computed tomography scan after 8 weeks of treatment: the size of the right heart tumor was 38.8 x 26.0 mm, with no pericardial or pleural fluid. The mediastinal lymph node under the carina is small, 10 x 5 mm, no longer compressing the mediastinal vascular system.
case_images: 10.1177_11795476241277663-fig2.jpg
case_images: PMC11401011_03_10.1177_11795476241277663-fig2.jpg
case_images: fig2-11795476241277663
case_images: No more compression of blood vessels in the mediastinum was seen (Figure 2B).
case_images: PMC11401011_02
case_images: PMC11401011_03
case_images: Echocardiography (RV: Right Ventricle, LV: Left Ventricle, RA: Right Atrium, LA: Left Atrium). (A and B) At admission, the heart tumor was 72 x 43 mm in size and adhered to the right atrial wall, tricuspid valve, and right ventricular wall, causing severe stenosis of the tricuspid valve and loss of nearly all function, with little pericardial fluid. There were no signs of cardiac tamponade. (C) After 3 weeks of treatment, the tumor size was 57.6 x 16.9 mm, partially obstructing the flow of the tricuspid valve. There was no pericardial fluid. (D) After 10 weeks of treatment, the tumor size was 23.8 x 19.1 mm, and the tricuspid valve functioned normally. There was no pericardial fluid.
case_images: 10.1177_11795476241277663-fig1.jpg
case_images: PMC11401011_04_10.1177_11795476241277663-fig1.jpg
case_images: fig1-11795476241277663
case_images: Echocardiogram before 5th cycle chemotherapy showed that the tumor size in the right heart chamber had decreased to 23.8 x 19.1 mm, the tricuspid valve was working well, and there was no pericardial fluid (Figure 1D).
case_images: Chest computed tomography. (A) Computed tomography scan upon admission: large tumor located in both right atrium and ventricle, with the size of 69.3 x 48.7 mm, obstructing blood flow through the tricuspid valve, causing the right atrium to dilate. The right pleural effusion was large, with a fluid thickness of 46.9 mm. The mediastinal tumor was located just below the carina, compressing and causing narrowing of the right pulmonary artery. (B) Computed tomography scan after 8 weeks of treatment: the size of the right heart tumor was 38.8 x 26.0 mm, with no pericardial or pleural fluid. The mediastinal lymph node under the carina is small, 10 x 5 mm, no longer compressing the mediastinal vascular system.
case_images: 10.1177_11795476241277663-fig2.jpg
case_images: PMC11401011_03_10.1177_11795476241277663-fig2.jpg
case_images: fig2-11795476241277663
case_images: No more compression of blood vessels in the mediastinum was seen (Figure 2B).
case_images: PMC11401011_04
case_images: Echocardiography (RV: Right Ventricle, LV: Left Ventricle, RA: Right Atrium, LA: Left Atrium). (A and B) At admission, the heart tumor was 72 x 43 mm in size and adhered to the right atrial wall, tricuspid valve, and right ventricular wall, causing severe stenosis of the tricuspid valve and loss of nearly all function, with little pericardial fluid. There were no signs of cardiac tamponade. (C) After 3 weeks of treatment, the tumor size was 57.6 x 16.9 mm, partially obstructing the flow of the tricuspid valve. There was no pericardial fluid. (D) After 10 weeks of treatment, the tumor size was 23.8 x 19.1 mm, and the tricuspid valve functioned normally. There was no pericardial fluid.
case_images: 10.1177_11795476241277663-fig1.jpg
case_images: PMC11401011_04_10.1177_11795476241277663-fig1.jpg
case_images: fig1-11795476241277663
case_images: Echocardiogram before 5th cycle chemotherapy showed that the tumor size in the right heart chamber had decreased to 23.8 x 19.1 mm, the tricuspid valve was working well, and there was no pericardial fluid (Figure 1D).
case_images: Positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro- D-glucose integrated with computed tomography (F18-FDG- PET/CT) after 4 cycles of treatment with R-CHOP: increased FDG uptake in the right ventricle.
case_images: 10.1177_11795476241277663-fig3.jpg
case_images: PMC11401011_04_10.1177_11795476241277663-fig3.jpg
case_images: fig3-11795476241277663
case_images: Whole body positron emission tomography and computed comography (PET/CT) scan using Fluorodeoxyglucose F18 (F18-FDG) at a dose of 0.15 mg/kg body weight showed an image of hyper F18-FDG uptake lesion (standardized uptake value-SUV max 4.5) in the right ventricle measuring 20 x 31 mm, no image of hyperF18-FDG uptake was seen in other locations (Figure 3). PET/CT images suggested that the malignant lesion in the heart had partially responded to treatment because the tumor in the heart had shrunk a lot and no lesions seen in other locations on PET/CT (Figure 3).