case_images: PMC7204369_01
case_images: PMC7204369_02
case_images: Hemoglobin-oxygen dissociation curve. The patient's curve is shifted to the right of the reference curve, consistent with reduced oxygen affinity. PO2 indicates partial pressure of oxygen.
case_images: CRIPE2020-2853531.001.jpg
case_images: PMC7204369_02_CRIPE2020-2853531.001.jpg
case_images: fig1
case_images: Hb-oxygen dissociation curve (P50, 33 mm Hg; reference range, 24-30 mm Hg) (Figure 1). Hb electrophoresis testing with cation-exchange high-performance liquid chromatography, capillary electrophoresis, and isoelectric focusing detected an abnormal variant peak (80.5% HbA, 2.2% HbA2, 1.4% fetal Hb, and 15.9% Hb variant).