case_images: PMC7184796_01
case_images: Hemorrhagic crust, scaly erosion on the lips, and generalized erythroderma with some foci of atypical target lesions on the face, trunk, and upper extremities (a, b).
case_images: cde-0012-0076-g01.jpg
case_images: PMC7184796_01_cde-0012-0076-g01.jpg
case_images: F1
case_images: Bilateral conjunctival injection, scaly hemorrhagic crusted erosion on both upper and lower lips, as well as mild erosion on bilateral buccal mucosa and genital site were noted (Fig. 1).
case_images: Superficial perivascular infiltration (predominately consisting of lymphocytes and eosinophils), mild epidermal hyperplasia, basal vacuolization, exocytosis, scattered necrotic keratinocytes, and prominent melanophages. Hematoxylin-eosin, original magnification x400.
case_images: cde-0012-0076-g02.jpg
case_images: PMC7184796_01_cde-0012-0076-g02.jpg
case_images: F2
case_images: Routine histopathology demonstrated superficial perivascular infiltration (predominately consisting of lymphocytes and eosinophils), mild epidermal hyperplasia, basal vacuolization, exocytosis, scattered necrotic keratinocyte, as well as prominent melanophages (Fig. 2).
case_images: Direct immunofluorescent study showed intercellular deposition of IgG resembling chicken wire feature and linear basement membrane zone staining with IgG (a) and C3 (b).
case_images: cde-0012-0076-g03.jpg
case_images: PMC7184796_01_cde-0012-0076-g03.jpg
case_images: F3
case_images: Direct immunofluorescence study showed intercellular deposition of IgG resembling chicken wire feature and linear basement membrane zone staining with IgG and C3 (Fig. 3).