case_images: PMC10844010_01
case_images: Lesional pictures of the patient. (A) There were multiple nodules, papules and abscesses in the occipital region. The abscesses were subcutaneously connected, and with fluctuation feeling. Purulent and smelling secretions were discharged. (B) Multiple hypertrophic scars, ulcers, and sinus tracts could be seen in the left armpit. Scar contracture restricted the patient's upper limb abduction and lifting activities. (C) Multiple abscesses, sinus formation, and scar hyperplasia were observed in the buttocks and perineal area. (D) Ultrasonographic examination of the occipital region, buttocks, and armpits revealed strong echoes of hair. The white arrow indicated hair with strong echoes under ultrasonographic examination. (E) Hair was found in the abscess cavity during surgery. (F) Pathological examination of one lesion revealed hyperplasia of subepidermal fibers, fat, and vascular tissues with collagen fibers. Local epidermal cysts formed with suppurative inflammation. Local squamous epithelial hyperplasia was accompanied by neutrophils, lymphocytes, histiocytes, and multinucleated giant cells. (G-I) The patient healed well after surgery and the 10-month follow-up revealed no recurrence.
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case_images: A 50-year-old male patient was hospitalized with multiple systemic abscesses, multiple ulcers, purulent sinus tracts, and sebaceous cysts (Figure 1).
case_images: Skin and mucous membrane pictures of the patient. (A) On the right side of the oral cavity, close to the opening of the parotid duct, light-yellow millet-sized flat papular lesions were visible in the buccal mucosa, which were clustered and fused into dense irregular patches. Their surface was smooth, and there was a sand-like sensation when touching them. (B) A sebaceous cyst was observed behind the right ear. (C) There were vitiligo skin lesions on scrotum and glans of the patient.
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case_images: FGs were observed in the buccal mucosa on the right side of the mouth with no dental abnormalities, a sebaceous cyst had grown behind the right ear for 1 year and there were vitiligo skin lesions on scrotum and glans of the patient (Figure 2).
case_images: This is the family genetic genealogy.
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case_images: Family history was positive for FOT, the family genetic genealogy is shown in Figure 3.