case_images: PMC6393871_01
case_images: Baseline CT scan shows the normal size and appearance of the spleen before using granulocyte colony-stimulating factor (G-CSF).
case_images: CRIONM2019-8174986.001.jpg
case_images: PMC6393871_01_CRIONM2019-8174986.001.jpg
case_images: fig1
case_images: Computed tomography (CT) scan ruled out infectious focus and showed hepatosplenomegaly with multiple splenic hypodensities and minimal perisplenic fluid which did not appear in the baseline scan (Figures 1 and 2).
case_images: Hepatosplenomegaly with multiple splenic hypodensities consistent with splenic infarction (arrow) after using G-CSF.
case_images: CRIONM2019-8174986.002.jpg
case_images: PMC6393871_01_CRIONM2019-8174986.002.jpg
case_images: fig2
case_images: Computed tomography (CT) scan ruled out infectious focus and showed hepatosplenomegaly with multiple splenic hypodensities and minimal perisplenic fluid which did not appear in the baseline scan (Figures 1 and 2).
case_images: Splenic tissue with focal hemorrhagic infarction necrosis and predominantly neutrophil polymorphs. (a-d) H/E-stained section.
case_images: CRIONM2019-8174986.003.jpg
case_images: PMC6393871_01_CRIONM2019-8174986.003.jpg
case_images: fig3
case_images: Infectious disease team advised for a splenic biopsy which showed splenic infarction only with no evidence of bacterial, fungal, viral, or malignant involvement (Figure 3).
case_images: Follow-up CT scan shows hepatosplenomegaly with interval improvement regarding the splenic infarction.
case_images: CRIONM2019-8174986.004.jpg
case_images: PMC6393871_01_CRIONM2019-8174986.004.jpg
case_images: fig4
case_images: General surgery team was consulted and did not recommend any surgical intervention since the follow-up CT scan turned out negative for splenic abscesses with interval improvement in the previous splenic wedge-shaped hypodensities (Figure 4).