case_images: PMC9946693_01
case_images: The pigmented nodular and blackish tumor with a pedunculated and infiltrated base measuring 4 cm.
case_images: cureus-0015-00000034105-i01.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i01.jpg
case_images: FIG1
case_images: On clinical examination, we found a nodular and blackish tumor of firm consistency with a pedunculated and infiltrated base measuring 4 cm (Figure 1).
case_images: Dermoscopy reveals a chaotic pattern with a blue-white veil and tree-trunk vascular pattern.
case_images: cureus-0015-00000034105-i02.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i02.jpg
case_images: FIG2
case_images: Dermoscopy revealed a chaotic pattern with a blue-white veil and tree-trunk vascular pattern (Figure 2).
case_images: Histological examination shows an ulcerated skin lesion whose dermis contains a biphasic, basaloid, and pigmented tumor (hematoxylin-eosin-saffron x100).
case_images: cureus-0015-00000034105-i03.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i03.jpg
case_images: FIG3
case_images: Optical microscopic examination showed an ulcerated skin lesion whose dermis contained a pigmented tumor arranged in lobules and sheets without connection with the epidermis (Figures 3, 4).
case_images: Histological examination shows adermal biphasic, basaloid, and pigmented tumor arranged in lobules and sheets without connection with the epidermis (hematoxylin-eosin-saffron x100).
case_images: cureus-0015-00000034105-i04.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i04.jpg
case_images: FIG4
case_images: Optical microscopic examination showed an ulcerated skin lesion whose dermis contained a pigmented tumor arranged in lobules and sheets without connection with the epidermis (Figures 3, 4).
case_images: Epithelial tumor cells are basaloid, with a pleomorphic nucleus, prominent nucleolus, and basophilic-reduced cytoplasm. Atypical mitotic figures are noted (hematoxylin-eosin-saffron x400).
case_images: cureus-0015-00000034105-i05.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i05.jpg
case_images: FIG5
case_images: Numerous mitotic figures were noted with atypical ones (22 mitoses/2 mm2) (Figure 5).
case_images: Epithelial basaloid cells are mixed with numerous heavily pigmented dendritic melanocytes (hematoxylin-eosin-saffron x200).
case_images: cureus-0015-00000034105-i06.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i06.jpg
case_images: FIG6
case_images: These cells were mixed with numerous heavily pigmented dendritic melanocytes (Figure 6).
case_images: Clusters of ghost cells are noted (hematoxylin-eosin-saffron x400).
case_images: cureus-0015-00000034105-i07.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i07.jpg
case_images: FIG7
case_images: Clusters of ghost cells (Figure 7) were noted along with foci of necrosis.
case_images: Cytoplasmic positive immunostaining by cytokeratin AE1/AE3 on epithelial tumoral cells (x200).
case_images: cureus-0015-00000034105-i08.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i08.jpg
case_images: FIG8
case_images: On immunohistochemical analysis, tumor cells expressed cytokeratin AE1/AE3 (Figure 8), p63 (Figure 9), and beta-catenin (nuclear and cytoplasmic staining) (Figure 10), while melanin markers (Melan A and HMB45) highlight non-atypical dendritic melanocytes (Figure 11).
case_images: Nuclear positive immunostaining by p63 on epithelial tumoral cells (x200).
case_images: cureus-0015-00000034105-i09.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i09.jpg
case_images: FIG9
case_images: On immunohistochemical analysis, tumor cells expressed cytokeratin AE1/AE3 (Figure 8), p63 (Figure 9), and beta-catenin (nuclear and cytoplasmic staining) (Figure 10), while melanin markers (Melan A and HMB45) highlight non-atypical dendritic melanocytes (Figure 11).
case_images: Strong nuclear and cytoplasmic positive immunostaining by beta-catenin on epithelial tumoral cells (x200).
case_images: cureus-0015-00000034105-i10.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i10.jpg
case_images: FIG10
case_images: On immunohistochemical analysis, tumor cells expressed cytokeratin AE1/AE3 (Figure 8), p63 (Figure 9), and beta-catenin (nuclear and cytoplasmic staining) (Figure 10), while melanin markers (Melan A and HMB45) highlight non-atypical dendritic melanocytes (Figure 11).
case_images: Melanin markers (Melan A and HMB45) highlight non-atypical dendritic melanocytes (x200).
case_images: cureus-0015-00000034105-i11.jpg
case_images: PMC9946693_01_cureus-0015-00000034105-i11.jpg
case_images: FIG11
case_images: On immunohistochemical analysis, tumor cells expressed cytokeratin AE1/AE3 (Figure 8), p63 (Figure 9), and beta-catenin (nuclear and cytoplasmic staining) (Figure 10), while melanin markers (Melan A and HMB45) highlight non-atypical dendritic melanocytes (Figure 11).