case_images: PMC11831238_01
case_images: Optical coherence tomographic (OCT) images showing changes over time in the macula of the right eye. A. OCT images of the right eye before the onset of macular edema. Visual acuity is 1.0.. B. OCT images of the right eye at the onset of macular edema (sixteen years after the initial visit). Macular edema in the central area can be observed. The retinal pigment epithelium (RPE) is irregular (red arrow). Decimal visual acuity is 0.8.. C. OCT images of the right eye during the treatment for macular edema (22 years after the initial visit). As in Figure 1B, macular edema in the central area can be observed. Visual acuity is 0.6.
case_images: cureus-0017-00000077606-i01.jpg
case_images: PMC11831238_01_cureus-0017-00000077606-i01.jpg
case_images: FIG1
case_images: The clinical course of both eyes and the pathological changes in the macula determined by optical coherence tomography (OCT) and OCT angiography (OCTA) are shown in Figures 1, 2. Sixteen years later, he developed diabetic macular edema (DME) in the right eye (Figure 1B) and an epiretinal membrane (ERM) in the left eye.
case_images: Optical coherence tomographic (OCT) and optical coherence tomography angiographic (OCTA) images showing changes over time in the macula of the left eye. A. OCT images of the left eye before the onset of macular edema, on the same day as Figure 1A. Visual acuity is 1.0.. B. OCT images of the left eye at the onset of macular edema (17 years after the initial visit). Macular edema in the central area can be observed. The visual acuity is 0.8.. C. OCT images of the left eye at the onset of macular neovascularization (22 years after the initial visit). Subretinal fluid and pigment epithelium detachment (red arrow) can be seen in the same position as in the image of Figure 2A. Visual acuity is 0.4.. D. OCTA images on the same day as Figure 2C. Macular neovascularization is observed (yellow arrow).
case_images: cureus-0017-00000077606-i02.jpg
case_images: PMC11831238_01_cureus-0017-00000077606-i02.jpg
case_images: FIG2
case_images: The clinical course of both eyes and the pathological changes in the macula determined by optical coherence tomography (OCT) and OCT angiography (OCTA) are shown in Figures 1, 2. The OCT images that were taken nine years after the initial visit revealed a small retinal pigment epithelial detachment (PED) in the left eye (Figure 2A). Seventeen years later, he developed DME in the left eye (Figure 2B), and his BCVA decreased to 0.8 in the right eye and 0.5 in the left eye. In addition, subretinal fluid appeared over the PED, and macular neovascularization (MNV) was observed beneath the PED, which had been observed 13 years before (Figures 2C, 2D).