case_images: PMC7184790_01
case_images: Spindle squamous cell carcinoma prior to excision.
case_images: cde-0012-0070-g01.jpg
case_images: PMC7184790_01_cde-0012-0070-g01.jpg
case_images: F1
case_images: At the time of excision, the tumor had grown to 3 x 3.5 cm (Fig. 1).
case_images: Hematoxylin-eosin stain of section from completely excised skin tumor located on the right gluteal region. Short black arrow: epidermis with hyperplasia. White arrow: poorly differentiated squamous cell carcinoma in upper dermis. Long black arrow: spindle cell carcinoma in dermis
case_images: cde-0012-0070-g02.jpg
case_images: PMC7184790_01_cde-0012-0070-g02.jpg
case_images: F2
case_images: The histology following the complete resection of the tumor showed a central area with papillomatosis and partly ulcerated surface, and transition from hyperplastic and dysplastic squamous epithelium to invasive low-differentiated SCC with a dominating spindle cell component (Fig. 2).
case_images: Hematoxylin-eosin stain of section of lymph node from right inguinal region (x10). Black arrow: lymphatic tissue. Blue arrow: metastatic spindle cell carcinoma. Lower right corner: metastatic spindle cell carcinoma, immunohistochemical positive reaction cytokeratin 14, confirming epithelial origin.
case_images: cde-0012-0070-g03.jpg
case_images: PMC7184790_01_cde-0012-0070-g03.jpg
case_images: F3
case_images: Immunohistochemically, a positive reaction for cytokeratin CK14 and P40 was observed as well as co-expression of vimentin (Fig. 3).