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case_images: Percentage of patients improved after Radiesse  injection, as reported in the 3 age groups and in the general population.
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case_images: A 37-year-old female patient (P.M.) for a preventive approach. (a) Baseline visit. (b) At 8 months after 2 Radiesse  injection sessions.
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case_images: At the baseline visit, she reported a facial skin thickness of grade 2 (thin) and a mild facial skin laxity and wrinkles (grade 1 on the Merz scale) (Figure 2a). The improvement achieved by the patient after 2 sessions of Radiesse  injection was graded as 4 (very good result) (Figure 2b). 
case_images: A 40-year-old female patient (F.F.) receiving the preventive approach. (a) Baseline visit. (b) At 6 months after one Radiesse  injection session.
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case_images: At the baseline visit, she presented with a facial skin thickness of grade 1 (very thin) and a mild facial skin laxity and wrinkles (grade 1 on the Merz scale) (Figure 3a). Radiesse  injection, after 1 session, allowed to achieve an improvement of 4 (very good result) (Figure 3b). 
case_images: A 42-year-old female patient (M.L.) for the treatment approach. (a) Baseline visit. (b) At 7 months after 2 Radiesse  injection sessions.
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case_images: At the baseline visit, she reported a facial skin thickness of grade 2 (thin) and a mild facial skin laxity and wrinkles (grade 1 on the Merz scale) (Figure 4a). The improvement achieved by the patient after 2 sessions of Radiesse  injection was graded as 4 (very good result) (Figure 4b). 
case_images: A 48-year-old female patient (A.S.) receiving a treatment approach. (a) Baseline visit. (b) At 10 months after 3 Radiesse  injection sessions.
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case_images: At baseline, her facial skin thickness was normal (grade 3) and the facial skin laxity and wrinkles were moderate (grade 2 on the Merz scale) (Figure 5a). The improvement reported after 3 sessions of Radiesse  injection was very good (grade 4) (Figure 5b). 
case_images: A 68-year-old female patient (M.R.) receiving a treatment approach. (a) Baseline visit. (b) At 12 months after 3 Radiesse  injection sessions.
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case_images: At baseline, her facial skin thickness was thin (grade 2) and the facial skin laxity and wrinkles were moderate (grade 2 on the Merz scale) (Figure 6a). The improvement reported after 3 sessions of Radiesse  injection was good (grade 3) (Figure 6b). 
case_images: Neck: This 58-year-old female patient was treated with 1.5 mL of Radiesse  + 6 mL of saline (final dilution, 1:4). Radiesse  was injected with a 27 and 30 Gauge needle and a cannula with 50 mm-length and 25 Gauge-diameter (27 and 30 Gauge were both used for convenience and considering the body region). (a) At baseline, her neck skin thickness was thin (grade 2) and the facial skin laxity and wrinkles were moderate (grade 2 on the Merz scale). (b) The improvement reported at 6 months after 3 sessions of Radiesse  injection was good (grade 3).
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case_images: Decolletage: This 62-year-old female patient was treated with 1.5 mL of Radiesse  + 9 mL of saline (final dilution, 1:6). Radiesse  was delivered via 27 and 30 Gauge needle in a microbolus injection and a cannula with 50 mm-length and 25 Gauge-diameter (27 and 30 Gauge were both used for convenience and considering the body region). (a) At baseline, her decolletage skin thickness was very thin (grade 1) and the decolletage skin laxity and wrinkles were mild (grade 1 on the Merz scale). (b) The improvement reported at 3 months after 6 sessions of Radiesse  injection was good (grade 3).
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case_images: Hands: This 50-year-old female patient was treated with 1.5 mL of Radiesse  + 3 mL of saline (final dilution, 1:2). Radiesse  was delivered via a cannula with 50 mm-length and 25 Gauge-diameter. (a) At baseline, her hand skin thickness was thin (grade 2) and the hand skin laxity and wrinkles were moderate (grade 2 on the Merz scale). (b) The improvement reported at 3 months after 2 sessions of Radiesse  injection was very good (grade 4).
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