case_images: PMC3420766_01
case_images: 3D reconstructed CT scan showing osteonecrosis of the humeral head, the acromion, lateral clavicle, and the glenoid in Gorham-Stout disease.
case_images: CRIM.RHEUMATOLOGY2011-565142.001.jpg
case_images: PMC3420766_01_CRIM.RHEUMATOLOGY2011-565142.001.jpg
case_images: fig1
case_images: Plain X-rays of both shoulders showed osteolyses of both humeral heads, glenoids, and lateral clavicles (Figures 1 and 2(a)).
case_images: Plain true a.p. X-rays of the right shoulder on first admission in 12/2007 (a), after disease limitation under bisphosphonate therapy in 03/2008 (b), postoperative after implantation of total shoulder prosthesis (c), 1-year followup showing no progression of the osteolyses and no signs of loosening of the prosthesis (d).
case_images: CRIM.RHEUMATOLOGY2011-565142.002.jpg
case_images: PMC3420766_01_CRIM.RHEUMATOLOGY2011-565142.002.jpg
case_images: fig2
case_images: Plain X-rays of both shoulders showed osteolyses of both humeral heads, glenoids, and lateral clavicles (Figures 1 and 2(a)). Early follow-up X-rays showed the termination of progressive osteolyses (Figure 2(b)). Plain X-rays showed a correctly implanted prosthesis without signs of loosening; in the glenoid and the lateral clavicle we found minor progression of the osteolysis (Figure 2(d)).
case_images: Macroscopic specimen of the humeral head showing massive osteolysis.
case_images: CRIM.RHEUMATOLOGY2011-565142.003.jpg
case_images: PMC3420766_01_CRIM.RHEUMATOLOGY2011-565142.003.jpg
case_images: fig3
case_images: Intraoperative findings where massive synovitis with significant thickening of the capsule and massive osteolysis of the humeral head (Figure 3) and the glenoid.
case_images: Histological stains showing altered osteoclastic resorption (acid phosphatase reaction 200x) (a); cortical and cancellous bone with stimulated turnover and marrow fibrosis (Goldner) (b).
case_images: CRIM.RHEUMATOLOGY2011-565142.004.jpg
case_images: PMC3420766_01_CRIM.RHEUMATOLOGY2011-565142.004.jpg
case_images: fig4
case_images: These findings were consistent with Gorham-Stout syndrome (Figure 4). 