case_images: PMC8531482_01
case_images: Patient's family tree according to the boy's mother.
case_images: fcvm-08-743341-g0001.jpg
case_images: PMC8531482_03_fcvm-08-743341-g0001.jpg
case_images: F1
case_images: BMI, which was insignificant, followed by a reduction of body mass and reaching a BMI at the third percentile at the age of 15, which requires attention and subsequent follow-up (Supplementary Figure 1). Because of this fact, we planned an increase in energy intake and scheduled a consultation with a pediatric dietologist.
case_images: PMC8531482_02
case_images: (A) Initial fibrocalcinous changes on the aortic root and on the mitral valve annulus. (B) Initial intima media thickness of the last 10 mm of the right common carotid artery.
case_images: fcvm-08-743341-g0002.jpg
case_images: PMC8531482_02_fcvm-08-743341-g0002.jpg
case_images: F2
case_images: Echocardiography revealed posterior annular calcification of the mitral valve and thickened and sclerotic aortic valve without any pathological gradient, normal ejection fraction (67%), and normal global longitudinal strain (-25%) (Figure 2). Intima-media thickness of the carotid arteries was elevated for the patient's age and corresponded to the values of a 30-year-old male (Figure 2).
case_images: Dynamics of LDL-C, non-HDL-C, Apolipoprotein B/A1 during the 5-year follow-up.
case_images: fcvm-08-743341-g0003.jpg
case_images: PMC8531482_03_fcvm-08-743341-g0003.jpg
case_images: F3
case_images: Since January 2020, the target levels have been successfully preserved below 3.5 mmol/l. (Figure 3). The dynamics of the different lipid profile values during the 5-year course are displayed in Figure 3.
case_images: PMC8531482_03
case_images: Patient's family tree according to the boy's mother.
case_images: fcvm-08-743341-g0001.jpg
case_images: PMC8531482_03_fcvm-08-743341-g0001.jpg
case_images: F1
case_images: BMI, which was insignificant, followed by a reduction of body mass and reaching a BMI at the third percentile at the age of 15, which requires attention and subsequent follow-up (Supplementary Figure 1). Because of this fact, we planned an increase in energy intake and scheduled a consultation with a pediatric dietologist.
case_images: Dynamics of LDL-C, non-HDL-C, Apolipoprotein B/A1 during the 5-year follow-up.
case_images: fcvm-08-743341-g0003.jpg
case_images: PMC8531482_03_fcvm-08-743341-g0003.jpg
case_images: F3
case_images: Since January 2020, the target levels have been successfully preserved below 3.5 mmol/l. (Figure 3). The dynamics of the different lipid profile values during the 5-year course are displayed in Figure 3.
case_images: Involution of the xanthomas during the 5-year follow-up.
case_images: fcvm-08-743341-g0004.jpg
case_images: PMC8531482_03_fcvm-08-743341-g0004.jpg
case_images: F4
case_images: Skin lesions' appearance during the 5-year period is shown on Figure 4.