case_images: PMC10212671_01
case_images: Ultrasonographic finding of the left thyroid nodule (28 mm x 19 mm in size).
case_images: CRIGM2023-6222432.001.jpg
case_images: PMC10212671_01_CRIGM2023-6222432.001.jpg
case_images: fig1
case_images: An ultrasound examination of the thyroid demonstrated a 4 mm x 3 mm nodule in the right thyroid lobe, two nodules in the left thyroid lobe, the smaller one measuring 4 mm x 4 mm in size and the larger one measuring 28 mm x 19 mm in size, which was classified as an ACR TI-RADS 5 nodule (Figure 1).
case_images: Macroscopic appearance of the thyroid lobe showing the cut surface of cribriform-morular thyroid carcinoma.
case_images: CRIGM2023-6222432.002.jpg
case_images: PMC10212671_01_CRIGM2023-6222432.002.jpg
case_images: fig2
case_images: Macroscopic examination of the left thyroid lobe showed one clean-edged nodule measuring 30 mm x 20 mm in size (Figure 2), while the right thyroid lobe showed no nodule.
case_images: Histopathological evaluation of the thyroid carcinoma. (a) Cribriform and papillary growth pattern of tumor cells, low power. (b) Tumor area showing a cribriform growth pattern along with a morular structure (black arrow), high power. (c) TTF-1 was positive in nuclear of tumor cells, high power. (d) TG was negative in tumor cells, high power. (e) beta-Catenin was positive in the cytoplasm and nucleus of tumor cells, high power. (f) CDX2 was positive in the nuclei of the morulae, high power.
case_images: CRIGM2023-6222432.003.jpg
case_images: PMC10212671_01_CRIGM2023-6222432.003.jpg
case_images: fig3
case_images: CDX2 was positive in the nuclei of the morulae, while TG was negative in the nucleus and cytoplasm of the tumor cells (Figure 3).