case_images: PMC4322880_01
case_images: Lung (A), liver (B), bone (C), and brain (D, E) metastases before start of nab-paclitaxel/trastuzumab treatment.. Abbreviation: nab, nanoparticle albumin-bound.
case_images: ott-8-289Fig1.jpg
case_images: PMC4322880_01_ott-8-289Fig1.jpg
case_images: f1-ott-8-289
case_images: A CT scan in September 2012 showed extensive progressive disease with appearance of new brain, liver, bone, and lung metastases (Figure 1).
case_images: Lung (A), Liver (B), Bone (C) and Brain (D) lesions after four courses of nab-paclitaxel/trastuzumab combination.. Abbreviation: nab, nanoparticle albumin-bound.
case_images: ott-8-289Fig2.jpg
case_images: PMC4322880_01_ott-8-289Fig2.jpg
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case_images: Four courses of nab-paclitaxel/trastuzumab therapy were delivered, with evidence of a partial response in the lung lesion, with substantial stable disease (SD) in the liver and bone metastases and a minimal response in the brain nodules (Figure 2).
case_images: Lung (A), Liver (B), Bone (C) and Brain (D) lesions after nine courses of nab-paclitaxel/trastuzumab combination.. Abbreviation: nab, nanoparticle albumin-bound.
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case_images: PMC4322880_01_ott-8-289Fig3.jpg
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case_images: Hence, she continued treatment for up to 14 cycles with the same schedule with substantial stable disease (Figure 3) and minimal neurological treatment-related toxicities.
case_images: Timeline of patient's diagnosis and treatments.. Abbreviations: BMs, brain metastasis; CHT, chemotherapy; CNS, central nervous system; FEC, fluouracil, epirubicin, and cyclophosphamide; HER, human epidermal growth factor receptor; PD, progressive disease; SRS, stereotactic radiosurgery; nab, nanoparticle albumin-bound; LHRH, luteinizing hormone-releasing hormone; RT, radiotherapy; WBRT, whole-brain radiotherapy.
case_images: ott-8-289Fig4.jpg
case_images: PMC4322880_01_ott-8-289Fig4.jpg
case_images: f4-ott-8-289
case_images: A complete list of all the patient's treatments is reported in Figure 4.