case_images: PMC11821627_01
case_images: Photographs of recurrent BCC. Initial skin lesion (A) demonstrating a deeply invasive nodular basal cell carcinoma, Resection of skin lesion with skin graft (B) with no residual BCC.
case_images: fonc-15-1500785-g001.jpg
case_images: PMC11821627_01_fonc-15-1500785-g001.jpg
case_images: f1
case_images: A 43-year-old Caucasian man presented with a large 8 x 8 cm ulcerated basal cell carcinoma located at the base of the neck overlying the right trapezius ( Figure 1A ). The patient subsequently underwent excision of the previously involved area with a skin graft repair ( Figure 1B ).
case_images: (A) The micrograph (100x) shows a nodular basal cell presenting as islands and nodules of basaloid cells with a peripheral palisading arrangement, embedded in a fibrous stroma. A noticeable cleft or retraction artifact separates the tumor islands from the surrounding stroma. The dermis shows a sparse inflammatory infiltrate. (B) The photomicrograph (20x) confirms the successful surgical removal of the site of the original basal cell carcinoma, with clear margins and satisfactory wound healing. The histological section illustrates a region of dense fibrous connective tissue, indicative of scar formation, with no evidence of residual basaloid cell nests. Collagen bundles are tightly packed and aligned parallel to the skin surface, characteristic of a reparative process.
case_images: fonc-15-1500785-g002.jpg
case_images: PMC11821627_01_fonc-15-1500785-g002.jpg
case_images: f2
case_images: Evaluation of the resection specimen by pathology confirmed a complete remission ( Figure 2 ).
case_images: Treatment schema.
case_images: fonc-15-1500785-g003.jpg
case_images: PMC11821627_01_fonc-15-1500785-g003.jpg
case_images: f3
case_images: A graphic schema to the treatment course is provided ( Figure 3 ).