case_images: PMC6619383_01
case_images: Breast carcinoma showing an adenocarcinoma with marked nuclear pleomorphism.. (H&E stain, X400 magnification).
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case_images: f1
case_images: Ki67 staining showed a proliferation index of 20% ( Figure 1).
case_images: Prostatic adenocarcinoma.. (H&E stain, X400 magnification).
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case_images: PMC6619383_01_f1000research-7-20122-g0001.jpg
case_images: f2
case_images: The tumour cells had large nuclei, conspicuous nucleoli and abundant pale eosinophilic cytoplasm ( Figure 2).
case_images: PMC6619383_02
case_images: Breast infiltrating duct carcinoma (H&E stain, X200 magnification).
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case_images:   The right breast histopathological assessment.  Histopathological examination showed an infiltrating duct carcinoma ( Figure 3), with a Nottingham combined histopathological grade of 1/3 (tubules 1, pleomorphism 2 and mitoses 1).
case_images: Oestrogen receptors diffusely expressed in the breast carcinoma (estrogen receptor (ER) immunohistochemistry, X200 magnification).
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case_images: Figure 4). Foci of low-grade cribriform ductal carcinoma in situ were also evident ( Figure 5).
case_images: Breast cribriform ductal carcinoma
  in situ (DCIS) (H&E stain, X200 magnification).
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case_images: f5
case_images: Figure 4). Foci of low-grade cribriform ductal carcinoma in situ were also evident ( Figure 5).
case_images: Invasive prostatic adenocarcinoma (H&E stain, X200 magnification).
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case_images: f6
case_images:   Prostate biopsy.  Biopsy results showed an invasive prostatic adenocarcinoma ( Figure 6), with a modified Gleason score of 9, and grade group 5, which was infiltrating into skeletal muscle ( Figure 7).
case_images: Invasive prostatic adenocarcinoma infiltrating into skeletal muscle (H&E stain, X200 magnification).
case_images: f1000research-7-20122-g0006.jpg
case_images: PMC6619383_02_f1000research-7-20122-g0006.jpg
case_images: f7
case_images:   Prostate biopsy.  Biopsy results showed an invasive prostatic adenocarcinoma ( Figure 6), with a modified Gleason score of 9, and grade group 5, which was infiltrating into skeletal muscle ( Figure 7).