case_images: PMC5787533_01
case_images: Ictal electroencephalogram (EEG) and pedigree of the family. (A) Ictal EEG with left frontocentral origination (arrow). A1-A3 show EEG evolution. A4 shows epilepsia partialis continua of the right lower limb without visible EEG change. (B) Pedigree of the family. The black square/circle indicates patients with the epilepsy phenotype; the double horizontal lines denote consanguineous marriage; the arrow shows the proband.
case_images: fneur-08-00750-g001c.jpg
case_images: PMC5787533_01_fneur-08-00750-g001c.jpg
case_images: F1
case_images: The activity quickly spread to the contralateral side with increased amplitude (Figure 1A). TBC1D24 gene, c.229_240del (p.82_84del). The homozygous mutation was inherited from her healthy parents who were heterozygous, which was consistent with autosomal recessive inheritance (Figure 1B and Supplementary Figure S1).
case_images: Morphometric analysis program (MAP) result. The crosshairs indicate the location of the MAP+ candidate. First row
  (A): T1-weighted magnetization prepared rapid acquisition with gradient echo images. Second row
  (B): gray-white matter junction z-score file, as the output of MAP processing of the T1-weighted image shown in the first row. Third row
  (C): T2-weighted fluid-attenuated inversion recovery images, chosen to best depict the MAP+ candidate. This was the best available image due to sub-optimal slice selection. There are no corresponding T2 changes.
case_images: fneur-08-00750-g002.jpg
case_images: PMC5787533_01_fneur-08-00750-g002.jpg
case_images: F2
case_images: The highlighted region might correlate with gray-white blurring on the underlying MRI. The MAP analysis identified a subtle abnormality candidate with a z-score over 4, a subtle gray-white blurring in the left medial parietal region (Figure 2).