case_images: PMC11330888_01
case_images: abdominal contrast-enhanced CT: (A) the contrast-enhanced scan of the tumor showed significant enhancement, corresponding to narrowing of the bile duct lumen. (B) In the delayed phase, tumor enhancement may be reduced.
case_images: fonc-14-1414665-g001.jpg
case_images: PMC11330888_01_fonc-14-1414665-g001.jpg
case_images: f1
case_images: Subsequent abdominal contrast-enhanced CT demonstrated uneven thickening of the duct wall above the pancreas, significant enhancement in the contrast-enhanced scan, narrow lumen, along with an enlarged gallbladder and upper bile duct ( Figure 1 ).
case_images: Immunohistochemical staining of the CCA. The CCA was positive for MLH1 (MutL Homolog 1), MSH2 (MutS Homolog 2), MSH6 (MutS Homolog 6) and PMS2 (PMS1 Homolog 2) (200x).
case_images: fonc-14-1414665-g002.jpg
case_images: PMC11330888_01_fonc-14-1414665-g002.jpg
case_images: f2
case_images: Surgical margins were negative, and IHC indicated for MLH1(+), MSH2(+), MSH6(+) and PMS2(+) in the tumor ( Figure 2 ).