case_images: PMC10630003_01
case_images: Photomicrograph from right mastectomy confirming ductal carcinoma in situ, high-grade, clinging, and cribriform patterns (hematoxylin and eosin (H&E) stain, 200x).
case_images: CRIPA2023-9979532.001.jpg
case_images: PMC10630003_01_CRIPA2023-9979532.001.jpg
case_images: fig1
case_images: High-grade DCIS with clinging and cribriform growth patterns and associated necrosis was confirmed (Figure 1).
case_images: Photomicrograph of the patient's right axillary sentinel lymph node with epithelial inclusion cyst showing central keratinous debris and a bland squamoid lining (hematoxylin and eosin (H&E) stain, 200x).
case_images: CRIPA2023-9979532.002.jpg
case_images: PMC10630003_01_CRIPA2023-9979532.002.jpg
case_images: fig2
case_images: In most areas, this intranodal cystic structure was lined by bland, spindled to cuboidal squamoid-appearing cells (Figure 2).
case_images: Photomicrograph of the patient's right axillary sentinel lymph node with epithelial inclusion cyst, highlighting positivity of peripheral cyst lining and central keratinous debris (cytokeratin 5/6 immunohistochemical study, 200x).
case_images: CRIPA2023-9979532.003.jpg
case_images: PMC10630003_01_CRIPA2023-9979532.003.jpg
case_images: fig3
case_images: Photomicrograph of the patient's right axillary sentinel lymph node epithelial inclusion cyst with scattered groups of overtly malignant cells in the cyst lining that were morphologically identical to the patient's ipsilateral high-grade ductal carcinoma in situ (hematoxylin and eosin (H&E) stain, 600x).
case_images: CRIPA2023-9979532.004.jpg
case_images: PMC10630003_01_CRIPA2023-9979532.004.jpg
case_images: fig4
case_images: Photomicrograph of the patient's right axillary sentinel axillary lymph node with epithelial inclusion cyst and involvement of the inclusion cyst by cells of high nuclear grade ductal carcinoma (TRPS1 immunohistochemical stain, 200x).
case_images: CRIPA2023-9979532.005.jpg
case_images: PMC10630003_01_CRIPA2023-9979532.005.jpg
case_images: fig5
case_images: IHC for p40, p63, and cytokeratin 5/6. Instead, they were positive for keratin AE1/AE3, cytokeratin 7, GATA3, CEA, and trichorhinophalangeal syndrome type 1 (TRPS1) (Figure 5).