case_images: PMC7669357_01
case_images: Bilateral legs with pigmentary changes.
case_images: CRIM2020-6186471.001.jpg
case_images: PMC7669357_01_CRIM2020-6186471.001.jpg
case_images: fig1
case_images: A 58-year-old white woman presented to the clinic with a hyperpigmented bluish-grey rash over the bilateral lower extremities persistent for two days (Figure 1).
case_images: Low-power magnification shows widely dispersed dermal pigmentation and an epidermis with no significant pathologic changes (20x; hematoxylin and eosin staining).
case_images: CRIM2020-6186471.002.jpg
case_images: PMC7669357_01_CRIM2020-6186471.002.jpg
case_images: fig2
case_images: Skin biopsy revealed scattered deposits of brown-black pigment in dermal spindle cells and minimal inflammation, indicating pigmentary rash (Figure 2).
case_images: Intermediate magnification shows coarse cytoplasmic granular brown pigmentation within aggregates of macrophages surrounding eccrine structures in the dermis (100x; hematoxylin and eosin staining).
case_images: CRIM2020-6186471.003.jpg
case_images: PMC7669357_01_CRIM2020-6186471.003.jpg
case_images: fig3
case_images: High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).
case_images: Intermediate magnification shows coarse cytoplasmic granular brown pigmentation within aggregates of macrophages surrounding eccrine structures in the dermis (200x; hematoxylin and eosin staining).
case_images: CRIM2020-6186471.004.jpg
case_images: PMC7669357_01_CRIM2020-6186471.004.jpg
case_images: fig4
case_images: High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).
case_images: High-power magnification displays coarse brown pigmented cytoplasmic granules within the dermal macrophages (400x; hematoxylin and eosin staining).
case_images: CRIM2020-6186471.005.jpg
case_images: PMC7669357_01_CRIM2020-6186471.005.jpg
case_images: fig5
case_images: High-power magnification displayed coarse brown pigmented cytoplasmic granules within the dermal macrophages (Figures 3-5).