case_images: PMC10694228_01
case_images: (A) MRI showed thickening and strengthening of the wall of the left external auditory canal cavity and left mastoiditis. (B) Axial CT showing soft tissue involvement of the left external and the middle ear, with external auditory canal - tympanum wall bone erosion. (C) 11-10 Postoperative pathology: granulation tissue proliferation with extensive neutrophil infiltration.
case_images: fcimb-13-1236414-g001.jpg
case_images: PMC10694228_01_fcimb-13-1236414-g001.jpg
case_images: f1
case_images: MRI revealed thickening and strengthening of the wall of left external auditory canal cavity and left mastoiditis ( Figure 1 ). CT scan confirmed the lesion of the temporal bone external auditory canal-tympanic wall ( Figure 1 ). Pathological examination showed granulation tissue proliferation with extensive neutrophil infiltration ( Figure 1 ).
case_images: mNGS results. (A) Aspergillus and Lymphocryptovirus were detected in case 1 by mNGS. Aspergillus was accounting for 14.11% of all microbial reads. The others were considered Probable normal flora. (B) Aspergillus and Staphylococcus were detected in case 2 by mNGS. Aspergillus was accounting for 32.51% of all microbial reads. Veillonella was considered Probable normal.
case_images: fcimb-13-1236414-g002.jpg
case_images: PMC10694228_02_fcimb-13-1236414-g002.jpg
case_images: f2
case_images: Pathological examinations showed granulation tissue ( Figure 4 ). mNGS on ear canal secretions and granulation tissue was performed immediately upon admission, and the results showed presence of Aspergillus flavus and Staphylococcus ( Figure 2 ).
case_images: The treatment timeline of the patient.
case_images: fcimb-13-1236414-g003.jpg
case_images: PMC10694228_02_fcimb-13-1236414-g003.jpg
case_images: f3
case_images: The entire treatment process is summarized in  Figure 3 .
case_images: PMC10694228_02
case_images: mNGS results. (A) Aspergillus and Lymphocryptovirus were detected in case 1 by mNGS. Aspergillus was accounting for 14.11% of all microbial reads. The others were considered Probable normal flora. (B) Aspergillus and Staphylococcus were detected in case 2 by mNGS. Aspergillus was accounting for 32.51% of all microbial reads. Veillonella was considered Probable normal.
case_images: fcimb-13-1236414-g002.jpg
case_images: PMC10694228_02_fcimb-13-1236414-g002.jpg
case_images: f2
case_images: Pathological examinations showed granulation tissue ( Figure 4 ). mNGS on ear canal secretions and granulation tissue was performed immediately upon admission, and the results showed presence of Aspergillus flavus and Staphylococcus ( Figure 2 ).
case_images: The treatment timeline of the patient.
case_images: fcimb-13-1236414-g003.jpg
case_images: PMC10694228_02_fcimb-13-1236414-g003.jpg
case_images: f3
case_images: The entire treatment process is summarized in  Figure 3 .
case_images: (A) MRI showed irregular tissue masses in the external auditory canal, with unclear boundaries. (B) Axial CT showing soft tissue involvement of the right external, with temporomandibular joint and eustachian tube bone erosion. (C) pathology: granulation tissue proliferation with extensive neutrophil infiltration.
case_images: fcimb-13-1236414-g004.jpg
case_images: PMC10694228_02_fcimb-13-1236414-g004.jpg
case_images: f4
case_images: CT scan showed the lesion in the temporal bone external auditory canal - tympanic wall ( Figure 4 ). MRI showed irregular tissue masses in the external auditory canal, with unclear boundaries ( Figure 4 ). Pathological examinations showed granulation tissue ( Figure 4 ). mNGS on ear canal secretions and granulation tissue was performed immediately upon admission, and the results showed presence of Aspergillus flavus and Staphylococcus ( Figure 2 ).