case_images: PMC11420039_01
case_images: Erythematous papules, pustules, and vesicles all over the body.
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case_images: f1
case_images: On admission, the patient exhibited erythematous papules, pustules ( Figure 1 ), particularly severe on the buttocks and both lower limbs, which were ulcerated with yellowish crusts.
case_images: (A, B) The buttocks and lower limbs are crusted and scabbed.
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case_images: PMC11420039_01_fimmu-15-1419054-g002.jpg
case_images: f2
case_images: The total area of skin lesions was approximately 1000 cm2, with an exudation area of approximately 200 cm2 ( Figures 2A, B ).
case_images: (A, B) (A) Direct immunofluorescence (DIF) shows linear deposition of IgG along the dermoepidermal junction at the periphery of the lesions. (B) Histological features on H&E staining reveal abundant infiltration of eosinophils.
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case_images: f3
case_images: For a definitive diagnosis, direct immunofluorescence (DIF) was performed on the skin lesions, showing linear deposits of IgG along the dermoepidermal junction, histological features consistent with HE staining, and significant infiltration of eosinophils ( Figures 3A, B ).
case_images: Chest CT scan shows increased lung markings with scattered patchy opacities.
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case_images: f4
case_images: Chest CT revealed patchy changes ( Figure 4 ), while head CT and MRI showed no significant abnormalities ( Figures 5 ).
case_images: Cranial MRI reveals several punctate low-density lesions in bilateral basal ganglia regions, with slightly deepened and widened cerebral sulci and fissures, centrally located, with no other significant abnormalities observed.
case_images: fimmu-15-1419054-g005.jpg
case_images: PMC11420039_01_fimmu-15-1419054-g005.jpg
case_images: f5
case_images: Chest CT revealed patchy changes ( Figure 4 ), while head CT and MRI showed no significant abnormalities ( Figures 5 ).