case_images: PMC9094363_01
case_images: (A-G) show the MRI by a decreased signal on the T1 sequence and increased signal intensity on the T2/FLAIR sequance showed a of the bilateral basal, certain ovale, frontal lobe, and parietal lobe, and F shows increased signal on the T2 sequence showed a of ganglia cervical cord.
case_images: fgene-13-845967-g001.jpg
case_images: PMC9094363_01_fgene-13-845967-g001.jpg
case_images: F1
case_images: Multifocal lesions were detected on MRI by a decreased signal on the T1 sequence, increased signal intensity on the T2/FLAIR, and diffusion-weighted imaging (DWI) sequence showed a of the bilateral basal, centrum ovale, frontal lobe, and parietal lobe, and increased signal on the T2 sequence showed a of ganglia cervical cord (Figure 1).
case_images: The genetic mutation and genetic lineage map.
case_images: fgene-13-845967-g002.jpg
case_images: PMC9094363_01_fgene-13-845967-g002.jpg
case_images: F2
case_images: The mother of proband has no obvious clinical symptoms at present, but it couldn not rule out the possibility she has no clinical symptoms in the future. (Figure 2).