case_images: PMC3420372_01
case_images: Axial MRI T2-weighted image (a) and contrast-enhanced coronal T-weighted image (b) showing heterogenous intensely enhancing mass involving left petrous temporal bone causing destruction of bone, extending medially left cerebellopontine angle cistern and inferiorly below base of skull. Axial CT scan (c) showing destruction of extensive destruction of the posterior petrous bone and middle ear structures.
case_images: CRIM.OTOLARYNGOLOGY2012-163851.001.jpg
case_images: PMC3420372_01_CRIM.OTOLARYNGOLOGY2012-163851.001.jpg
case_images: fig1
case_images: MRI demonstrated (Figure 1(a), arrow) a large heterogenous mass involving left petrous temporal bone causing destruction of bone (Figure 1(b), arrow), extending medially left cerebello-pontine angle cistern and inferiorly below base of skull. Computed tomography (CT) showed extensive destruction of the posterior petrous bone and middle ear structures with involvement of internal auditory canal (Figure 1(c), arrow).
case_images: Microscopy shows typical papillary structures (2(a), H&E x 100), lined by benign looking low cuboidal epithelial cells (2(b), H&E x 200). Tumor cells are immunopositive for cytokeratin (2(c), IHC (CK)[Daco] x 200) and S100 (2(d), IHC (S100)[Daco] x 200).
case_images: CRIM.OTOLARYNGOLOGY2012-163851.002.jpg
case_images: PMC3420372_01_CRIM.OTOLARYNGOLOGY2012-163851.002.jpg
case_images: fig2
case_images: Microscopically (Figures 2(a) and 2(b)) the tumor was composed of typical papillary structures with central fibrovascular core lined by benign looking, single layer of cuboidal to columnar epithelial cells. Immunohistochemically the tumor cells are positive for cytokeratin (CK), S100 (Figures 2(c) and 2(d)) and epithelial membrane antigen (EMA).