case_images: PMC11772059_01
case_images: Course of myoglobin and creatine kinase as well as treatment modalities during the critical phase of a patient with drug-induced rhabdomyolysis and severe metabolic acidosis.
case_images: CRICC2025-3968057.001.jpg
case_images: PMC11772059_01_CRICC2025-3968057.001.jpg
case_images: fig1
case_images: Laboratory tests indicated significantly elevated retention parameters, along with excessively increased CK (92,047 mug/L) and myoglobin levels (136,554 mug/L) (Table 1 and Figure 1). After rapid initial stabilization under this combination, a renewed surge in rhabdomyolysis parameters occurred, which led to the replacement of the AV1000S Ultraflux dialysis filter with an Ultraflux EMiC2 filter with enhanced middle molecule clearance (Fresenius Medical Care, Bad Homburg, Germany) from Day 3 to Day 6 (Figure 1). Following consistent decreases in CK and myoglobin values, CytoSorb therapy could be discontinued after a total of nine consecutive sessions (Figure 1).