case_images: PMC2822249_01
case_images: Lymph node biopsy (H&E stain, x20). Microscopically, the mass exhibits diffuse effacement of lymph node architecture and granulomas. Inset is the enlarged picture (x200) of the area indicated by arrow.
case_images: jkms-19-130-g001.jpg
case_images: PMC2822249_01_jkms-19-130-g001.jpg
case_images: F1
case_images: Microscopically, the mass exhibited diffuse effacement of lymph node architecture and multiple granulomas (Fig. 1).
case_images: Lymph node biopsy (H&E stain, x200). Reed-Sternberg cells (solid arrow) are scattered among a background of many mature lympocytes. Arrow inside inset shows mitosis.
case_images: jkms-19-130-g002.jpg
case_images: PMC2822249_01_jkms-19-130-g002.jpg
case_images: F2
case_images: Many large atypical mononuclear or binuclear cells, including Reed-Sternberg cells, were scattered among many mature lymphocytes rare eosinophils, and plasma cells (Fig. 2).
case_images: Sural nerve biopsy (modified Gomori trichrome stain, x100). The sural nerve biopsy shows several myelin digestion chambers (arrow), suggesting axonal degeneration.
case_images: jkms-19-130-g003.jpg
case_images: PMC2822249_01_jkms-19-130-g003.jpg
case_images: F3
case_images: The sural nerve biopsy showed several myelin digestion chambers, suggesting axonal degeneration on modified Gomori stain (Fig. 3).
case_images: Sural nerve biopsy (EM findings, x7,000). The sural nerve shows loss of small and large myelinated fibers and degenerating axons with myelin ovoids (arrow), suggesting axonal neuropathy.
case_images: jkms-19-130-g004.jpg
case_images: PMC2822249_01_jkms-19-130-g004.jpg
case_images: F4
case_images: On electron microscopy, the sural nerve showed the loss of small and large myelinated fibers with axonal sprouting and myelin ovoids, suggesting an axonal neuropathy (Fig. 4).