case_images: PMC10991732_01
case_images: Breast biopsy specimen with hematoxylin and eosin (HE) staining. (A) Specimen 1 (x100). (B) Specimen 1 (x200). (C) Specimen 2 (x100). (D) Specimen 2 (x200).
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case_images: PMC10991732_01_fonc-14-1296328-g001.jpg
case_images: f1
case_images: In October 2019, she underwent needle biopsy of a right breast mass and was diagnosed with PBA ( Figure 1 ). CT revealed a malignant tumor in the right renal pelvis that had metastasized from other origins, or a bleeding pseudoaneurysm ( Supplementary Figures 1, 2 ).
case_images: Breast biopsy specimen with immunohistochemical staining. (A) Specimen 1, CD31. (B) Specimen 1, CD34. (C) Specimen 2, CD31. (D) Specimen 2, CD34.
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case_images: PMC10991732_01_fonc-14-1296328-g002.jpg
case_images: f2
case_images: Immunohistochemical staining showed AE1/AE3 (- [Indicates a negative result]), CK7 (-), GATA3 (-), Vimentin (+ [Indicates a positive result]), CD34 (+), CD31 (+), SMA (-), calponin (-), ER (-), PR (-), CerbB-2 (0), beta-catenin (cytoplasmic +), CD10 (-), and Ki67 (approximately 70% +) ( Figure 2 ). CT revealed a malignant tumor in the right renal pelvis that had metastasized from other origins, or a bleeding pseudoaneurysm ( Supplementary Figures 1, 2 ).
case_images: Computed tomography (CT) scan showing an increase in the number and size of lung lesions compared to previous results, with a slight increase in the right renal sinus mass. (A) Chest CT scan, horizontal position. (B) Chest CT scan, coronal position. (C) Abdominal CT scan, horizontal position. (D) Abdominal CT scan, arterial phase, horizontal position.
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case_images: PMC10991732_01_fonc-14-1296328-g003.jpg
case_images: f3
case_images: After 3 months, CT showed an increase in the number and size of the lung lesions, and the tumor in the right renal pelvis was slightly larger, with the largest cross-sectional size of approximately 6.60 x 8.10 cm ( Figure 3 ). Renal angiographic ultrasound showed that the tumor began to enhance at 17 s and then rapidly increased as a whole, with no enhancement visible inside the tumor throughout, reaching a peak at 20 s with high enhancement, and subsiding slightly earlier than the surrounding renal parenchyma ( Supplementary Figure 3 ).