case_images: PMC8776648_01
case_images: Spine computed tomography (CT) demonstrated a slightly hyperdense nodule lesion with a little spot low and high density of the C1-2 level, and well-circumscribed without obvious bone destruction (A). Contrast-enhanced magnetic resonance imaging (MRI) of the spine; the lesion was isointense on T1-weighted images (B), and hypo- to hyperintense on T2-weighted images (C). After intravenous administration of gadolinium, the tumor showed obvious peripheral enhancement, presenting a growing tendency along the right second intervertebral foramen and compressing the spinal cord to the left side (D).
case_images: fsurg-08-722254-g0001.jpg
case_images: PMC8776648_01_fsurg-08-722254-g0001.jpg
case_images: F1
case_images: A spine CT scan showed a slightly hyperdense nodule lesion with a little spot low and high density of C1-2 level, well-circumscribed without evident destruction of the surrounding bone (Figure 1A). Magnetic resonance imaging (MRI) of the spine showed that the mass was 20 mm x 16 x 17 mm, isointense onT1-weighted images (T1WI), and hypo- to hyper-intense on T2-weighted images (T2WI) of the intradural extramedullary tumors at the C1-2 level (Figures 1B,C). After intravenous administration of gadolinium, the mass showed obvious enhancement, presenting a growing tendency along the right second intervertebral foramen and compressing the spinal cord to the left side, without bone and soft tissue destruction (Figure 1D). Postoperative MRI re-examination revealed no obvious residual or recurrence 2 weeks after the surgery (Supplementary Figure 1).
case_images: Histopathological examination showed that the lesion was grayish red, well-circumscribed, with average blood supply, soft in quality, and located in the intraspinal subdural region (A) (hematoxylin and eosin staining; magnification, x 100). The tumor cells were positive for (B) S-100 and (C) SOX10 (magnification, x 100).
case_images: fsurg-08-722254-g0002.jpg
case_images: PMC8776648_01_fsurg-08-722254-g0002.jpg
case_images: F2
case_images: Histopathological examination showed that the lesion was grayish red, soft, well-circumscribed with average blood supply, and located in the intraspinal subdural region (Figure 2A). Immunohistochemical analysis revealed that the tumor cells were positive for S-100 protein (Figure 2B) and SOX10 (Figure 2C), and negative for SMA, CD34, and STAT6.