case_images: PMC11126250_01
case_images: Ulceroproliferative growth extending from 46 to the retromolar region
case_images: JOMFP-28-130-g001.jpg
case_images: PMC11126250_01_JOMFP-28-130-g001.jpg
case_images: jomfp_142_23-f001
case_images: Intraoral examination on inspection revealed a nonhealing ulceroproliferative, sessile growth of size 5 cm x 3.5 cm in the mandibular right buccal mucosa extending from 46 to the retromolar region [Figure 1].
case_images: Orthopantomogram showing generalised horizontal loss of bone in 45 46 regions
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case_images: PMC11126250_01_JOMFP-28-130-g002.jpg
case_images: jomfp_142_23-f002
case_images: Radiographical findings revealed generalised horizontal loss of bone with respect to 45 46 regions [Figure 2].
case_images: Photomicrograph of haematoxylin and eosin stained section showing (a) fibrinopurulent membrane lining the connective tissue (40x magnification), (b) spindle shaped neoplastic sells arranged in fascicular and storiform pattern with adjoining myxoid arears (100x magnification) and (c) neoplastic cells showing features of malignancy (400x)
case_images: JOMFP-28-130-g003.jpg
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case_images: jomfp_142_23-f003
case_images: Few aberrant mitotic figures were present [Figure 3].
case_images: Photomicrograph showing strong positive expression of CD68 (a), vimentin (b), and KI67 (c) in immunohistochemistry under 100x magnification
case_images: JOMFP-28-130-g004.jpg
case_images: PMC11126250_01_JOMFP-28-130-g004.jpg
case_images: jomfp_142_23-f004
case_images: Upon immunohistochemistry (IHC), the tissue was strongly positive for vimentin, CD68 and KI67 confirming the presence of histiocytes and fibroblast like cells in the connective tissue stroma [Figure 4].