case_images: PMC10758892_01
case_images: Radiological assessment of the prostate gland mass. PET scans in sagittal, axial, and coronal (left to right) planes demonstrate radiotracer uptake in the prostate gland.
case_images: IJU5-7-77-g001.jpg
case_images: PMC10758892_01_IJU5-7-77-g001.jpg
case_images: iju512672-fig-0001
case_images: Imaging studies showed an abscess-like mass involving the prostate gland bilaterally and rapidly rising PSA (4.39 ng/mL), suspicious for locally/regionally recurrent prostate cancer (Fig. 1).
case_images: Morphology of mucin-producing urothelial-type adenocarcinoma of the prostate. Atypical columnar to cuboidal glandular cells containing intracytoplasmic mucin were seen infiltrating the prostate gland (a,b:arrows). The area with sarcomatoid differentiation was closely mixed with the adenocarcinoma (a, arrowheads and inset box). Pleomorphic areas of tumor cells were noted (c, arrows). Subsequent transurethral resection of the tumor demonstrating sarcomatoid areas is shown in (d). Digitally scanned H&E stained slides, 20x magnification; (a) inset box and (d), 40x magnification (Aperio GT 450, Leica Biosystems).
case_images: IJU5-7-77-g002.jpg
case_images: PMC10758892_02_IJU5-7-77-g002.jpg
case_images: iju512672-fig-0002
case_images: At 12 months, the patient's scan redemonstrated local progression that led to a transurethral resection (TUR) of the tumor which showed predominant high-grade sarcomatoid areas (Fig. 2d), morphologically like the previous biopsy.
case_images: PMC10758892_02
case_images: Morphology of mucin-producing urothelial-type adenocarcinoma of the prostate. Atypical columnar to cuboidal glandular cells containing intracytoplasmic mucin were seen infiltrating the prostate gland (a,b:arrows). The area with sarcomatoid differentiation was closely mixed with the adenocarcinoma (a, arrowheads and inset box). Pleomorphic areas of tumor cells were noted (c, arrows). Subsequent transurethral resection of the tumor demonstrating sarcomatoid areas is shown in (d). Digitally scanned H&E stained slides, 20x magnification; (a) inset box and (d), 40x magnification (Aperio GT 450, Leica Biosystems).
case_images: IJU5-7-77-g002.jpg
case_images: PMC10758892_02_IJU5-7-77-g002.jpg
case_images: iju512672-fig-0002
case_images: At 12 months, the patient's scan redemonstrated local progression that led to a transurethral resection (TUR) of the tumor which showed predominant high-grade sarcomatoid areas (Fig. 2d), morphologically like the previous biopsy.