case_images: PMC3420495_01
case_images: Low power view of Lymph Node with plasma cell variant castleman's and showing features of Kaposi sarcoma at the top left quadrant.
case_images: CRIM.PATHOLOGY2011-809567.001.jpg
case_images: PMC3420495_01_CRIM.PATHOLOGY2011-809567.001.jpg
case_images: fig1
case_images: The lymph node biopsy (see Figures 1 and 2) report returned as "Atrophic follicles, germinal centre involution, lymphocytic depletion in paracortex: (i) +ve staining for kappa + lambda, (ii) appearances compatible with subacute/chronic stage of HIV lymphadenitis, and (iii) no evidence of lymphoma or carcinoma seen." 
case_images: High power view of the node with plasma cell variant of castlemans.
case_images: CRIM.PATHOLOGY2011-809567.002.jpg
case_images: PMC3420495_01_CRIM.PATHOLOGY2011-809567.002.jpg
case_images: fig2
case_images: The lymph node biopsy (see Figures 1 and 2) report returned as "Atrophic follicles, germinal centre involution, lymphocytic depletion in paracortex: (i) +ve staining for kappa + lambda, (ii) appearances compatible with subacute/chronic stage of HIV lymphadenitis, and (iii) no evidence of lymphoma or carcinoma seen." 
case_images: Composite picture of splenic biopsy showing H & E picture on (a), CD79a in the top and bottom (b) and HHV-8 staining cells on (c).
case_images: CRIM.PATHOLOGY2011-809567.003.jpg
case_images: PMC3420495_01_CRIM.PATHOLOGY2011-809567.003.jpg
case_images: fig3
case_images: A splenic biopsy (Figure 3) result showed widespread Kaposi's sarcoma and plasma cell variant multifocal Castleman's disease.
case_images: High power view of Leishmania organisms.
case_images: CRIM.PATHOLOGY2011-809567.005.jpg
case_images: PMC3420495_01_CRIM.PATHOLOGY2011-809567.005.jpg
case_images: fig5
case_images: A bone marrow trephine biopsy also showed Leishmaniasis (Figure 5) which was treated with ambisome. Numerous Human Herpes Virus 8 (HHV8) lymphoid cells (Figure 5) and vascular proliferation which are also strongly HHV8+:typically seen with cutaneous KS."  