case_images: PMC10702400_01
case_images: (A) Abdominal CT image demonstrated a 9 x 7 cm size, hypoattenuating mass in the left lobe of the liver prior to contrast material administration. (B) After contrast material injection, the mass exhibited less enhancement compared to the surrounding liver parenchyma (white arrow).
case_images: 10.1177_11795476231215907-fig1.jpg
case_images: PMC10702400_01_10.1177_11795476231215907-fig1.jpg
case_images: fig1-11795476231215907
case_images: Abdominal computed tomography (CT) exhibited a low-density mass measuring 9 x 7 cm in the left lobe of the liver before contrast material administration, which showed less enhancement compared to the surrounding liver parenchyma after contrast material injection (Figure 1).
case_images: (A) Macroscopically, a distinct, lobulated, yellowish-white mass measuring 10 cm in maximum diameter was observed. (B and C) Microscopic examination revealed a tumor with a fibrous capsule (black arrow) and interlacing bands of uniformly spindle-shaped cells with elongated nuclei arranged in a palisading pattern. (D) Additionally, there was a mild infiltration of chronic inflammatory cells, including lymphocytes and histocytes. No evidence of nuclear atypia, mitosis, or necrosis was observed (Hematoxylin-Eosin, Bx40, Cx100, Dx200).
case_images: 10.1177_11795476231215907-fig2.jpg
case_images: PMC10702400_01_10.1177_11795476231215907-fig2.jpg
case_images: fig2-11795476231215907
case_images: Macroscopic examination revealed a well-defined, lobulated, yellowish-white mass measuring 10 cm in maximum diameter (Figure 2A). No significant evidence of nuclear atypia, mitotic activity, or necrosis was observed (Figure 2B-D).
case_images: Immunohistochemistry (magnification x100) revealed that tumor cells were diffusely and strongly positive for (A) S-100, but negative for (B) CD117, (C) DOG-1, (D) SMA, (E) CD34, and (F) ALK-1. The histopathological findings confirmed the final diagnosis of primary hepatic schwannoma.
case_images: 10.1177_11795476231215907-fig3.jpg
case_images: PMC10702400_01_10.1177_11795476231215907-fig3.jpg
case_images: fig3-11795476231215907
case_images: Immunohistochemical staining indicated tumor cells were diffusely and strongly positive for S-100, but negative for CD117, DOG-1, SMA, CD34, Desmin and ALK-1 (Figure 3).