case_images: PMC5994262_01
case_images: (a) Chest X-ray showed 6 x 4.5 cm white opaque lesion in mediastinal area (blue arrow) and (b) CT-scan revealed hypodense mass 6.7 x 7.5 cm, suggesting inferoanterior mediastinal cyst (blue arrow). Encapsulated cystic lesion compressed adjacent aorta and pericardium.
case_images: CRIPA2018-8270516.001.jpg
case_images: PMC5994262_01_CRIPA2018-8270516.001.jpg
case_images: fig1
case_images: Thoracic CT-scan revealed a cystic lesion, 6.7 x 7.5 cm located in inferior part of the anterior mediastinum (Figure 1).
case_images: (a) An Island of pancreas tissue bordered by thick fibrous tissue with pancreatic interlobular duct around it (H&E-4x). (b) Pancreas tissue consists of exocrine gland with eosinophilic granular cytoplasm and endocrine cells (Islets of Langerhans) (H&E-10x). (c) Increase in the endocrine portion (Islets of Langerhans) of pancreatic tissue (H&E-40x). (d) Mediastinal cyst lined by simple cuboid and columnar epithelium (H&E-10x). (e) Hyperplasia of thymic gland was observed (HE-4x). (f) Normal appearance of lymphocytes and Hassall's corpuscles (H&E-10x).
case_images: CRIPA2018-8270516.002.jpg
case_images: PMC5994262_01_CRIPA2018-8270516.002.jpg
case_images: fig2
case_images: It consisted of acinar exocrine cells with interlobular ducts and abundant endocrine cells (Islets of Langerhans) (Figure 2).
case_images: Immunohistochemical staining. (a and b) High expression of insulin in pancreatic beta cells of islets of Langerhans (10x-40x). (c and d) Strong positivity of chromogranin in islets of Langerhans (10x-40x). (e and f) Cytokeratin showed strong positivity in acinic cells and pancreatic duct; meanwhile endocrine cells showed very weak expression (4x-10x).
case_images: CRIPA2018-8270516.003.jpg
case_images: PMC5994262_01_CRIPA2018-8270516.003.jpg
case_images: fig3
case_images: Immunohistochemical staining for insulin showed strongly positive Beta cells of the islets of Langerhans within the ectopic pancreatic tissue (Figure 3).