case_images: PMC6369462_01
case_images: Low power (2x) view of the entire biopsy demonstrating a classic plate-like proliferation of keratinocytes parallel to the epidermis (a). Higher power (10x) of another section of the tumor shows the presence of numerous keratocysts (b) and a net-like architecture with frequent connections of the plate to the above epidermis (c).
case_images: CRIPA2019-4606493.001.jpg
case_images: PMC6369462_01_CRIPA2019-4606493.001.jpg
case_images: fig1
case_images: A biopsy was performed and histopathologic examination showed an overall well circumscribed lesion (Figure 1) with a subepidermal, horizontally oriented, plate-like proliferation of pale appearing squamous epithelial cells, with numerous points of connection with the overlying epidermis and peripheral palisading (Figure 1).
case_images: Higher power (20x) shows a keratocyst with no visible granular layer and abrupt keratinization (a). The pale pink cytoplasm of tumor cells is evidence of tumor glycogenation and the characteristic differentiation (b).
case_images: CRIPA2019-4606493.002.jpg
case_images: PMC6369462_01_CRIPA2019-4606493.002.jpg
case_images: fig2
case_images: Numerous keratocysts are noted at the base, while, notably, no visible granular layer is present (Figure 2).