case_images: PMC7501541_01
case_images: Clinical image of scrotal lesions palpable, firm, soft, and mobile subcutaneous nodules.
case_images: CRIU2020-8826627.001.jpg
case_images: PMC7501541_01_CRIU2020-8826627.001.jpg
case_images: fig1
case_images: Physical examination showed soft, mobile, subcutaneous nodules, and erythematous papules of different sizes (0.5 to 1.5 cm in diameter) in the scrotum (Figure 1).
case_images: Bone scintigraphy showing several metastatic lesions, including in the lumbar spine.
case_images: CRIU2020-8826627.002.jpg
case_images: PMC7501541_01_CRIU2020-8826627.002.jpg
case_images: fig2
case_images: Bone scintigraphy revealed bone metastases, which were also identified on the MRI, a lumbar epiduritis was also noted (Figures 2 and 3).
case_images: Axial section of an MRI in weighted sequence T1 with gadolinium injection showing irregular contrast uptake of epidural space with heterogeneity of the bone structure vertebral.
case_images: CRIU2020-8826627.003.jpg
case_images: PMC7501541_01_CRIU2020-8826627.003.jpg
case_images: fig3
case_images: Bone scintigraphy revealed bone metastases, which were also identified on the MRI, a lumbar epiduritis was also noted (Figures 2 and 3).
case_images: A carcinomatous tumor proliferation located in a small cell stroma, a cytoplasmic shelter, and a monomorphic nucleus sometimes nucleated in the scrotal skin tissue.
case_images: CRIU2020-8826627.004.jpg
case_images: PMC7501541_01_CRIU2020-8826627.004.jpg
case_images: fig4
case_images: PSA immunohistochemistry (IHC) was positive which confirms the prostatic origin (Figures 4 and 5).
case_images: (a) Immunohistochemistry (G x100): positive labeling with anti-PSA antibody. (b) Immunohistochemistry (x40): positive labeling with anti-PSA antibody with image of perineural neoplastic invasion.
case_images: CRIU2020-8826627.005.jpg
case_images: PMC7501541_01_CRIU2020-8826627.005.jpg
case_images: fig5
case_images: PSA immunohistochemistry (IHC) was positive which confirms the prostatic origin (Figures 4 and 5).
case_images: Regression of skin nodules after hormone therapy.
case_images: CRIU2020-8826627.006.jpg
case_images: PMC7501541_01_CRIU2020-8826627.006.jpg
case_images: fig6
case_images: After 3 months, PSA levels dropped to 45 ng/mL and a considerable regression of scrotal skin lesions was noted (Figure 6).