case_images: PMC10804246_01
case_images: Localization of the cyst in the third ventricle (A). The cyst was wedged between the splayed columns of the fornix, not obstructing the left foramen of Monro (B). A viscous substance hardened after formalin fixation with a thin fibrous capsule was observed when the cyst was sectioned (C,D).
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case_images: diagnostics-14-00100-f001
case_images: There was a 2 cm pale grayish-green rounded cyst formation partially filling and enlarging the third ventricle (Figure 1A), which was wedged between the fornix splayed columns, non-occluding the left foramen of Monro (Figure 1B). Sectioning the cyst formation revealed a viscous substance indurated after formalin fixation with a thin fibrous capsule (Figure 1C,D).
case_images: Cystic lesion, filled with a strongly PAS-positive amorphous content (A) and covered by hypocellular fibrous wall lined by simple columnar epithelium with variable cilia or mucin, flattened without squamous metaplasia (B). Columnar, ciliated epithelial cells compose the cyst wall. There was no abnormal increase in goblet cells or any cellular atypia or thickening of the wall. Cyst content consisted of a mucoid material with detached epithelial cell clusters (A x40, B x80).
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case_images: diagnostics-14-00100-f002
case_images: Periodic acid-Schiff (PAS) staining (specifically for the identification of mucin) of the cyst formation showed a cystic lesion filled with a strongly PAS-positive amorphous content and covered by a hypocellular fibrous wall and by a simple columnar epithelium with a variable amount of cilia or mucin, flattened without squamous metaplasia (Figure 2A,B).
case_images: Immunohistochemical staining of CK7 using a human-specific anti-Cytokeratin 7 antibody. The cyst epithelium (arrows) is positive for CK7 (x40, x80).
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case_images: diagnostics-14-00100-f003
case_images: In order to verify whether it was a cyst or cancerous tissue, we performed an immunohistochemical analysis and found that the specimen was positive for cytokeratin 7 (CK7) expression (Figure 3), a structural protein expressed in epithelia lining the cavities of internal organs, while it was negative for ALCIAN, CK20, CEA, Cam 5.2,
case_images: Hypercontracted myofibrils fragmentation and hypercontracted or coagulated sarcomeres (arrows) band formation. Absence of edema, hemorrhage, and myofiber vacuolization (H&E x 40).
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case_images: diagnostics-14-00100-f004
case_images: Myocardial tissue blocks showed myocell fragmentation and pathological band with hyper eosinophilia of the hypercontracted myocardial cells and myofibrils rhexis into cross-fiber (Figure 4).