case_images: PMC10797034_01
case_images: (A) Hematoxylin and eosin (HE) staining; (B) Modified Gomori trichrome (MGT) staining; (C) Succinate dehydrogenase (SDH) staining; and (D) Cytochrome c oxidase (COX) staining. (A) HE staining revealed different muscle fiber sizes and scattered atrophic muscle fibers. (B) MGT staining revealed a few ragged-red fibers. (C) SDH staining revealed scattered ragged-blue fibers. (D) COX staining revealed several scattered negative muscle fibers.
case_images: fneur-14-1268053-g0001.jpg
case_images: PMC10797034_01_fneur-14-1268053-g0001.jpg
case_images: F1
case_images: Furthermore, hematoxylin and eosin staining revealed muscle fibers of different sizes and scattered atrophic muscle fibers (Figure 1A). Modified Gomori trichrome staining revealed a few ragged-red fibers (RRF) (Figure 1B). Moreover, succinate dehydrogenase (SDH) staining revealed scattered ragged-blue fibers (RBF) (Figure 1C). Cytochrome c oxidase (COX) staining revealed several scattered negative muscle fibers (Figure 1D).
case_images: Triangular muscle mitochondrial gene testing. A single deletion (chrmM:8469-13447, arrow) was observed in the mitochondrial gene.
case_images: fneur-14-1268053-g0002.jpg
case_images: PMC10797034_01_fneur-14-1268053-g0002.jpg
case_images: F2
case_images: Based on these findings, the patient was finally diagnosed with CPEO (Figure 2).