case_images: PMC4100599_01
case_images: (a) A T1-weighted magnetic resonance imaging (MRI) of the sellar region showing a diffusely enlarged pituitary gland measuring 1.6 (W)x1.1 (H) cm with lateral extensions encasing both cavernous sinuses bilaterally and mild compression of the optic chiasm. (b) A T1-weighted MRI of the sellar region after contrast showing heterogeneous enhancement of the enlarged pituitary gland along with the thickened lateral walls of both cavernous sinuses.
case_images: edmcr-2014-140029-g001.jpg
case_images: PMC4100599_01_edmcr-2014-140029-g001.jpg
case_images: fig1
case_images: The differential diagnosis was inflammatory or infiltrative disorders of the pituitary gland (Fig. 1).
case_images: (a) Haematoxylin and eosin stain (20x original magnification). Sheets of monomorphic neoplastic lymphoid cells with pleomorphic nuclei, coarse chromatin and little cytoplasm. (b) Ki-67 stain (4x original magnification). Malignant lymphoid cells stained heavily with a Ki-67 index of 100%.
case_images: edmcr-2014-140029-g002.jpg
case_images: PMC4100599_01_edmcr-2014-140029-g002.jpg
case_images: fig2
case_images: The histological diagnosis was malignant B-cell lymphoma (Fig. 2a). Further immunohistochemical staining indicated that the malignant lymphoid cells were positive for CD20 and CD10 and negative for BCL2; Ki-67 was 100% (Fig. 2b).