case_images: PMC11724724_01
case_images: Laryngoscopy (a) and computed tomography (b) on the admission of the patient, a previously healthy 44-year-old male. His larynx was surprisingly swollen (red arrows).
case_images: CRIM2025-6638796.001.jpg
case_images: PMC11724724_01_CRIM2025-6638796.001.jpg
case_images: fig1
case_images: We thus immediately intubated him with bronchoscopy, which revealed severe pharyngeal and laryngeal edema (Figure 1). The patient's airway was almost completely obstructed (Figure 1).
case_images: The patient's clinical course during admission. ALT: alanine transaminase; AZM: azithromycin; CLDM: clindamycin; CRP: C-reactive protein; CTRX: ceftriaxone; MEPM: meropenem; P-Amy: pancreatic amylase.
case_images: CRIM2025-6638796.002.jpg
case_images: PMC11724724_01_CRIM2025-6638796.002.jpg
case_images: fig2
case_images: After the patient's admission, we administered methylprednisolone, antibiotics, and bronchodilators (salbutamol and adrenaline), as shown in Figure 2.
case_images: The patient's skin rash on Days 20 (a) and 38 (b).
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case_images: PMC11724724_01_CRIM2025-6638796.003.jpg
case_images: fig3
case_images: By Day 18, he had gradually developed generalized erythema (Figure 3), and we discontinued all of the medications and prescribed fexofenadine and topical glucocorticoid for possible allergic etiology.
case_images: The appearance of the changes in the patient's epiglottis.
case_images: CRIM2025-6638796.004.jpg
case_images: PMC11724724_01_CRIM2025-6638796.004.jpg
case_images: fig4
case_images: Figures 4 and 5 depict the changes in the patient's epiglottis and tonsil swelling.
case_images: Endoscopic findings of the patient's right palatine (*) and lingual ( ) tonsillitis. (a) Acute tonsillitis and swelling and erosion of the right side of the epiglottis were observed (arrow). (b) The swelling of the right side of the epiglottis improved almost completely, and the erosion disappeared. The acute tonsillitis improved but mildly persisted. (c) Mild edematous swelling of the epiglottis persisted, but the right lingual and palatine tonsillitis completely resolved (distant view).
case_images: CRIM2025-6638796.005.jpg
case_images: PMC11724724_01_CRIM2025-6638796.005.jpg
case_images: fig5
case_images: Figures 4 and 5 depict the changes in the patient's epiglottis and tonsil swelling.