case_images: PMC4994818_01
case_images: a Plain lumbar X-ray lateral view showing radiolucency of the L1 vertebral body. Sagittal (b) and axial (c) computed tomography showing an osteolytic lesion of the L1 vertebral body
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case_images: PMC4994818_01_40064_2016_3006_Fig1_HTML.jpg
case_images: Fig1
case_images: Plain lumbar spine X-ray revealed a radiolucency at the L1 vertebral body (Fig. 1a). Computed tomography (CT) showed a defined osteolytic lesion involving the left side of the vertebral body and pedicle of L1 (Fig. 1b, c).
case_images: Sagittal magnetic resonance images showing low signal intensity changes of the L1 vertebral body on T1-weighted images (a) and high signal intensity changes on T2-weighted images (b). Axial magnetic resonance images showing low signal intensity changes of the L1 vertebral body and pedicle on T1-weighted images (c) and high signal intensity changes on T2-weighted images (d)
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case_images: PMC4994818_01_40064_2016_3006_Fig2_HTML.jpg
case_images: Fig2
case_images: Magnetic resonance imaging (MRI) revealed low-signal intensity changes on T1-weighted images and high-signal intensity changes on T2-weighted images of the L1 vertebral body (Fig. 2).
case_images: a High-power photomicrography showing Langerhans histiocytes and mixed numerous eosinophils. b Neoplastic cells showing folded and convoluted nuclei with intra-nuclear groove resembling coffee beans (arrow). Immunohistochemical staining for S-100 protein (c) and CD-1a (d) showing immunoreactivity of Langerhans cells
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case_images: PMC4994818_01_40064_2016_3006_Fig3_HTML.jpg
case_images: Fig3
case_images: Immunohistochemistry confirmed LCH with diffuse immunoreactivity of S-100 and CD1a (Fig. 3).
case_images: Sagittal (a) and axial (b) computed tomography a year after biopsy showing bone remodeling of the previous osteolytic lesion of the L1 vertebral body
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case_images: PMC4994818_01_40064_2016_3006_Fig4_HTML.jpg
case_images: Fig4
case_images: Notably, follow-up CT revealed significant bone remodeling one year after biopsy, but the height of the vertebral body remained stable without further collapse, and lumbar kyphosis did not occur (Fig. 4).