case_images: PMC10787133_01
case_images: PMC10787133_02
case_images: targetoid lesions on the lower extremities
case_images: PAMJ-46-55-g001.jpg
case_images: PMC10787133_02_PAMJ-46-55-g001.jpg
case_images: F1
case_images: The physical examination showed multiple sharply demarcated erythematous annular scaly plaques with a necrotic area in the center which looked like targetoid lesions with a diameter between 3-6 cm on his lower extremities (Figure 1).
case_images: the clinical manifestations on the trunk and extremities
case_images: PAMJ-46-55-g002.jpg
case_images: PMC10787133_02_PAMJ-46-55-g002.jpg
case_images: F2
case_images: Palms and soles are also affected (Figure 2).
case_images: the histopathology examination; A) the histopathology examination revealed the epidermis with basal cell vacuolar degeneration and the dermis layer showed a lymphocytic infiltrate along the dermal-epidermal junction and the superficial dermis layer which was compatible with erythema multiforme (20x magnification); B) histopathology of the same lesion with 400x magnification
case_images: PAMJ-46-55-g003.jpg
case_images: PMC10787133_02_PAMJ-46-55-g003.jpg
case_images: F3
case_images: The histopathology examination revealed basal cell vacuolar degeneration in the epidermal layer and the dermal layer showed lymphocytic infiltrates along the dermal-epidermal junction and the superficial dermis, consistent with EM (Figure 3).