case_images: PMC6587379_01
case_images: Annular generalized pustular psoriasis: widespread pustular lesions over an erythematous base forming a circinate pattern. (a) Right upper arm, (b) forearms bilaterally, (c) trunk and (d) back.
case_images: 10.1177_2050313X19857392-fig1.jpg
case_images: PMC6587379_01_10.1177_2050313X19857392-fig1.jpg
case_images: fig1-2050313X19857392
case_images: On examination, she presented with a generalized poly-annular and poly-cyclic pustular and papular eruption with trailing scale and erythema affecting 50% of her body - including the trunk and limbs but sparing the face (Figure 1).
case_images: Histological examination of annular generalized pustular psoriasis: (a) H&E staining demonstrates classic psoriasiform changes of acanthosis, parakeratosis, subcorneal pustules, mild spongiosis and (b) histochemical staining demonstrates IL-17A in dermal infiltrates.
case_images: 10.1177_2050313X19857392-fig2.jpg
case_images: PMC6587379_02_10.1177_2050313X19857392-fig2.jpg
case_images: fig2-2050313X19857392
case_images: Immunohistochemical analysis of lesional skin demonstrated interleukin (IL)-17A expression by the epidermis and dermal lymphocytes (Figure 2(b)).
case_images: PMC6587379_02
case_images: Histological examination of annular generalized pustular psoriasis: (a) H&E staining demonstrates classic psoriasiform changes of acanthosis, parakeratosis, subcorneal pustules, mild spongiosis and (b) histochemical staining demonstrates IL-17A in dermal infiltrates.
case_images: 10.1177_2050313X19857392-fig2.jpg
case_images: PMC6587379_02_10.1177_2050313X19857392-fig2.jpg
case_images: fig2-2050313X19857392
case_images: Immunohistochemical analysis of lesional skin demonstrated interleukin (IL)-17A expression by the epidermis and dermal lymphocytes (Figure 2(b)).