case_images: PMC7670738_01
case_images: PMC7670738_02
case_images: Frequency of blood transfusions of study subjects according to their hematological disease. ITP: idiopathic thrombocytopenic purpura; SCD: sickle cell disease.
case_images: 1678-9849-rsbmt-54-e20200066-gf1.jpg
case_images: PMC7670738_02_1678-9849-rsbmt-54-e20200066-gf1.jpg
case_images: f1
case_images: He was among the patient group with the highest blood transfusion rates in the past 12 months (Figure 1).
case_images: Phylogenetic tree showing the genetic similarity between the 5' LTR region aligned sequence (611pb) of the HTLV-2 strain isolated in this study, and the sequences of 48 strains from the Genbank database. The tree was constructed using the neighbor-joining method and a bootstrap of 1,000 replicates. The branch of the isolated sample (JLM151) is labeled by a red dot.
case_images: 1678-9849-rsbmt-54-e20200066-gf2.jpg
case_images: PMC7670738_02_1678-9849-rsbmt-54-e20200066-gf2.jpg
case_images: f2
case_images: The JLM151 sample (GenBank accession number MN 266910) was clustered within the subtype HTLV-2c, the same clade of the samples isolated from the Kayapo tribe (AF306731 and AF306731) (Figure 2).The distribution of HTLV-2 subtypes suggests that the viruses were gradually and distinctly dispersed around the world through different migratory events starting from the Africa continent.