case_images: PMC9382061_01
case_images: (a) Sheets of foamy histiocytes with scattered lymphocytes and exceptional
  eosinophils. Touton (arrow) multinucleated cell (HE x40). (b) Dense
  infiltrate of CD68 positive histiocytes (HE x10). (c) S100 negative with
  positive internal control (HE x10). (d) CD1a negative with positive internal
  control (HE x10).
case_images: 10.1177_2050313X221117693-fig1.jpg
case_images: PMC9382061_01_10.1177_2050313X221117693-fig1.jpg
case_images: fig1-2050313X221117693
case_images: All histiocytes were positive for CD68 and were negative for CD1a and S100 (Figure 1).
case_images: (a) Multiple yellow papules and nodules on the head and upper trunk of
  12-month-old patient. (b) Patient continued to develop new lesions while
  others started to regress at 2 years old. (c) At the age of 4 years, most
  JXGs had completely regressed leaving hyperpigmented macules.
case_images: 10.1177_2050313X221117693-fig2.jpg
case_images: PMC9382061_01_10.1177_2050313X221117693-fig2.jpg
case_images: fig2-2050313X221117693
case_images: However, by the age of 4 years, most skin lesions had regressed leaving hyperpigmented macules and no new ocular lesion had appeared, while most conjunctival lesions had stabilized or regressed (Figure 2).