case_images: PMC5846923_01
case_images: Radiograph of the right distal forelimb (dorsopalmar view) showing loose screws (red arrow) and associated soft tissue swelling (yellow arrow)
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case_images: Radiographs of the limb revealed significant lysis and soft tissue swelling around two loose screws at the previous surgical site (Figure 1).
case_images: (a) Haematoxylin and eosin photomicrograph (X 40) revealing a poorly defined, densely cellular tumour infiltrating through the dermis. (b) Haematoxylin and eosin photomicrograph (X 200) showing a monomorphic population of neoplastic round cells
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case_images: There was no evidence of epitheliotropism (Figure 2).
case_images: Immunohistochemistry against CD3, counterstained with haematoxylin (X 200). Many of the neoplastic cells exhibit moderate-to-strong cytoplasmic staining indicating a tumour of T lymphocyte origin
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case_images: Immunohistochemistry confirmed a predominant population of round cells exhibiting strong cytoplasmic positivity for CD3 antigen (Figure 3).
case_images: Photograph of the primary lesion at time of referral to Victorian Animal Cancer Care
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case_images: Two weeks later, the cat presented to Victorian Animal Cancer Care, Melbourne, Australia, where the primary lesion was ulcerated and swollen (Figure 4).
case_images: Photograph demonstrating progression of the primary lesion. The cat was euthanased on the day this photograph was taken
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case_images: Four weeks following commencement of chemotherapy, progressive disease was noted within the cutaneous lesion (Figure 5) and right axillary lymph node.