case_images: PMC3434468_01
case_images: Clinical Overview: A - (smaller increase) tumor appearance, color of mucosa, slow and exophytic growing, sessile deployment,
  smooth and well delineated surface. B - major increase.
case_images: TODENTJ-6-111_F1.jpg
case_images: PMC3434468_01_TODENTJ-6-111_F1.jpg
case_images: F1
case_images: It also had a smooth surface and a well-defined boundary (Fig. 1).
case_images: Axial CT scan showing a nodular image with sharp boundaries in part, measuring approximately 2.0x1.0 cm. A - CT soft tissue
  window. B - CT hard tissue window.
case_images: TODENTJ-6-111_F2.jpg
case_images: PMC3434468_01_TODENTJ-6-111_F2.jpg
case_images: F2
case_images: The coronal CT scan with soft tissue and hard tissue window revealed a nodular area with soft tissue density, limits partially clear, measuring 2x2x1cm (Fig. 2).
case_images: Excisional biopsy: A - wedge incision. B - removal of debris. C - suture. D - surgical specimen.
case_images: TODENTJ-6-111_F3.jpg
case_images: PMC3434468_01_TODENTJ-6-111_F3.jpg
case_images: F3
case_images: Then this new specimen was sent for histopathological and immunohistochemistry analysis to confirm the histogenetic origin of the lesion (Fig. 3).
case_images: HE, 200x: ductal formations showing inner layer of cuboidal cells and also proliferation of solidly arranged polygonal cells.
case_images: TODENTJ-6-111_F4.jpg
case_images: PMC3434468_01_TODENTJ-6-111_F4.jpg
case_images: F4
case_images: It also revealed proliferation of polygonal cells arranged in a solid way (Fig. 4).
case_images: PMC3434468_02
case_images: Immunohistochemistry, 200x - Protein positivity for AE1/AE3 proteins in the inner cuboidal cells of the ductal formations.
case_images: TODENTJ-6-111_F5.jpg
case_images: PMC3434468_02_TODENTJ-6-111_F5.jpg
case_images: F5
case_images: The immunohistochemical evaluation was positive for antibodies AE1/AE3, S-100, p63 and Ki-67 in about 25% of neoplastic cells, resulting in a profile consistent with an epithelial-myoepithelial carcinoma with high-grade transformation (Fig. 5, 6, 7 and 8).
case_images: Immunohistochemistry, 200x - Diffuse staining for S100 protein in tumor cells.
case_images: TODENTJ-6-111_F6.jpg
case_images: PMC3434468_02_TODENTJ-6-111_F6.jpg
case_images: F6
case_images: The immunohistochemical evaluation was positive for antibodies AE1/AE3, S-100, p63 and Ki-67 in about 25% of neoplastic cells, resulting in a profile consistent with an epithelial-myoepithelial carcinoma with high-grade transformation (Fig. 5, 6, 7 and 8).
case_images: Immunohistochemistry, 200x - Nuclear staining for p-63 protein.
case_images: TODENTJ-6-111_F7.jpg
case_images: PMC3434468_02_TODENTJ-6-111_F7.jpg
case_images: F7
case_images: The immunohistochemical evaluation was positive for antibodies AE1/AE3, S-100, p63 and Ki-67 in about 25% of neoplastic cells, resulting in a profile consistent with an epithelial-myoepithelial carcinoma with high-grade transformation (Fig. 5, 6, 7 and 8).
case_images: Immunohistochemistry, 200x - Intense nuclear staining for Ki67 protein in several tumor cells.
case_images: TODENTJ-6-111_F8.jpg
case_images: PMC3434468_02_TODENTJ-6-111_F8.jpg
case_images: F8
case_images: The immunohistochemical evaluation was positive for antibodies AE1/AE3, S-100, p63 and Ki-67 in about 25% of neoplastic cells, resulting in a profile consistent with an epithelial-myoepithelial carcinoma with high-grade transformation (Fig. 5, 6, 7 and 8).