case_images: PMC6232806_01
case_images: PET/CT with an infiltrative mass in the mediastinum with diffuse uptake.
case_images: CRIHEM2018-6154709.001.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.001.jpg
case_images: fig1
case_images: Due to concern for lymphoma and findings on CT of the chest, a PET/CT was ordered which showed an infiltrative mass in the mediastinum with diffuse uptake (maximum standardized uptake value (SUV) 5.94 (Figure 1).
case_images: PET CT with hypermetabolic mass within the left iliac bone.
case_images: CRIHEM2018-6154709.002.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.002.jpg
case_images: fig2
case_images: Finally, there was a hypermetabolic mass within the left iliac bone with a maximum SUV 11.71 (Figure 2).
case_images: Hematoxylin and eosin stain: lymphoid tissue composed of small, mitotically inactive cells with round to slightly irregular nuclear contours and scant cytoplasm.
case_images: CRIHEM2018-6154709.003.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.003.jpg
case_images: fig3
case_images: Immunohistochemistry positive for CD20.
case_images: CRIHEM2018-6154709.004.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.004.jpg
case_images: fig4
case_images: Immunohistochemical stains showed that the cells were positive for CD20 (Figure 4) and CD5 (Figure 5) and negative for Cyclin D1 (Figure 6).
case_images: Immunohistochemistry positive for CD5.
case_images: CRIHEM2018-6154709.005.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.005.jpg
case_images: fig5
case_images: Immunohistochemical stains showed that the cells were positive for CD20 (Figure 4) and CD5 (Figure 5) and negative for Cyclin D1 (Figure 6).
case_images: Immunohistochemistry negative for Cyclin D1.
case_images: CRIHEM2018-6154709.006.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.006.jpg
case_images: fig6
case_images: Immunohistochemical stains showed that the cells were positive for CD20 (Figure 4) and CD5 (Figure 5) and negative for Cyclin D1 (Figure 6).
case_images: Hematoxylin and eosin stain: a malignant infiltrate of small, mitotically inactive lymphocytes replacing the marrow space in the biopsy from left iliac bone.
case_images: CRIHEM2018-6154709.007.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.007.jpg
case_images: fig7
case_images: PET avid left iliac bone. Pathology from that biopsy showed both bone and marrow with involvement of CLL/SLL (Figure 7).
case_images: Flow cytometry from the left iliac bone biopsy revealed monoclonal kappa light chain restricted B-cell population phenotypically consistent with CLL/SLL.
case_images: CRIHEM2018-6154709.008.jpg
case_images: PMC6232806_01_CRIHEM2018-6154709.008.jpg
case_images: fig8