case_images: PMC10758891_01
case_images: Right inguinal fold with firm papulonodules, several of which form confluent, hyperpigmented to violaceous plaques.
case_images: IJU5-7-5-g001.jpg
case_images: PMC10758891_01_IJU5-7-5-g001.jpg
case_images: iju512653-fig-0001
case_images: His physical exam was notable for firm papulonodules, several of which formed confluent, hyperpigmented to violaceous plaques involving the right inguinal fold (Fig. 1).
case_images: (a) A nested proliferation of tumor cells in the dermis with focal glandular differentiation (H&E, original magnification 100x). The inset image shows skin with papillary dermal edema, perivascular inflammation, and a neoplastic proliferation extending into the deep dermis (H&E, original magnification, 20x). (b) GATA3 stain highlighting the tumor cells with nuclear staining. (Immunostain, original magnification 100x). (c) Cytokeratin 20 stain highlighting the tumor cells with cytoplasmic staining (Immunostain, original magnification 100x).
case_images: IJU5-7-5-g002.jpg
case_images: PMC10758891_01_IJU5-7-5-g002.jpg
case_images: iju512653-fig-0002
case_images: Immunohistochemistry revealed that the tumor cells were positive for CK20 and GATA3 and negative for CK7 (Fig. 2).