case_images: PMC6466958_01
case_images: CT abdomen and pelvis without contrast showing a mass attached to the right lobe of the liver and peritoneal ascites. (a) Axial section. (b) Coronal section.
case_images: CRIONM2019-6375693.001.jpg
case_images: PMC6466958_01_CRIONM2019-6375693.001.jpg
case_images: fig1
case_images: A computed tomogram (CT) scan of the abdomen and pelvis without contrast (Figures 1(a) and 1(b)) showed a 6.3 cm hyper dense focus adjacent to the right lobe of the liver, the large ascites, and the findings suggestive of peritoneal carcinomatosis along with diffuse body wall mass, large ascites, and grossly enlarged uterus containing multiple large partially calcified fibroids.
case_images: Pathology. High Power. H&E stain showing sheets of tumor cells with hyperchromatic nuclei and scant cytoplasm.
case_images: CRIONM2019-6375693.002.jpg
case_images: PMC6466958_01_CRIONM2019-6375693.002.jpg
case_images: fig2
case_images: Figure 2 shows H&E staining, and Figure 3 shows synaptophysin staining of tumor tissue. FoundationOne study identified genomic PIK3CA amplification showing potential clinical benefit if treated with everolimus and temsirolimus.
case_images: IHC (synaptophysin) stain of the tumor tissue showing positive synaptophysin confirming the tumor was neuroendocrine.
case_images: CRIONM2019-6375693.003.jpg
case_images: PMC6466958_01_CRIONM2019-6375693.003.jpg
case_images: fig3
case_images: Figure 2 shows H&E staining, and Figure 3 shows synaptophysin staining of tumor tissue. FoundationOne study identified genomic PIK3CA amplification showing potential clinical benefit if treated with everolimus and temsirolimus.