Intra-tympanic Dexamethasone for Sudden Sensory Neural Hearing Loss: A Multicentre Trial

The sudden sensory neural hearing loss is a condition with considerable incidence and confers some risk factors behind. Use of systemic steroids is effective for the condition but with several adverse effects, so; use of local intratympanic injection of steroid is safer option warrants efficacy confirmation. This trial included 60 patients with the condition allocated into three arms according to steroid treatment; oral, local and combined. The patients were compared before and after and were assessed with pure tone audiometry. The result show statistically significant difference for each arm in before and after testing but not inter-groups comparison. This study adds evidence to enhance the use of steroid as an intra-tympanic topical therapy in managing sudden sensory neural hearing loss.