the pfizer vaccine that I have read about does need to be kept at -70C.  There are only a few facilities with the requirements to store it.  There are other vaccines in the running which do not require such a low temperature.  Article written in August by Childrens Health Defense "A dozen Covid-19 vaccines are undergoing clinical trials, leading a crowded field that now numbers approximately 170 candidates. Several of the U.S. contenders—Moderna, Pfizer/BioNTech and Ar  318f  cturus Therapeutics—are deploying never-before-approved messenger RNA (mRNA) technology, an experimental approach designed to turn the body’s cells into viral-protein-making factories." "A key technical challenge is to get the vaccines’ bulky RNA “payload” into the cells intact—without it breaking down prior to arriving at its destination. In other words, mRNA vaccines will not work without an in-built delivery mechanism that enables the mRNA to shove its way into a cell’s cytoplasm. The chosen solution is to use trendy biotech “carrier systems” involving lipid nanoparticles (LNPs). LNPs “encapsulate the mRNA constructs to protect them from degradation and promote cellular uptake” and, additionally, rev up the immune system (a property that vaccine scientists tamely describe as LNPs’ “inherent adjuvant properties”). The LNP formulations in the three Covid-19 vaccines are also “PEGylated,” meaning that the vaccine nanoparticles are coated with a synthetic, nondegradable and increasingly controversial polymer called polyethylene glycol (PEG)." I have not been able to find a definitive answer if pfizer uses PEG but the moderna vaccine can be stored at warmer temperatures because of its proprietary liquid nanoparticle formula. https://childrenshealthdefense.org/news/components-of-mrna-technology-could-lead-to-significant-adverse-events-in-one-or-more-of-our-clinical-trials-says-moderna/ other good information which explains the temperature requirement: https://www.lifesitenews.com/news/pfizer-coronavirus-vaccine-must-be-stored-at-70c-colder-than-antarctica https://www.phgfoundation.org/briefing/rna-vaccines   Introduction to RNA vaccines Cambridge University https://phys.org/news/2020-01-rna-effect-dna.html    RNA affects DNA This doctor may be a little out there for some people but she talks about the vaccine and Darpa https://z3news.com/w/major-ethical-health-freedom-privacy-dangers-inherent-vaccine-carrie-madej-watch/