Floyd had enough fentanyl 11 ng/ml to make him pass out! Plus other drugs were in his system. It could have been a cardiac arrest due to drugs. Check this out: Fentanyl "Overdose results in respiratory depression which is reversible with naloxone. Sudden death can also occur because of cardiac arrest or severe anaphylactic reaction.  The estimated lethal dose of fentanyl in humans is 2 mg. The recommended serum concentration for analgesia is 1–2 ng/ml and for anaesthesia it is 10–20 ng/ml. Blood concentrations of approximately 7 ng/ml or greater have been associated with fatalities where poly-substance use was involved. While fatalities have been reported after therapeutic use, many deaths have occurred as a result of the misuse of pharmaceutical products. Both used and unused fentanyl patches have been injected, smoked, snorted or taken orally with fatal consequences." https://www.emcdda.europa.eu/publications/drug-profiles/fentanyl_en From the autopsy report: VI. Toxicology (see attached report for full details; testing performed on antemortem blood specimens collected 5/25/20 at 9:00 p.m. at HHC and on postmortem urine) A. Blood drug and novel psychoactive substances screens: 1. Fentanyl 11 ng/mL 2. Norfentanyl 5.6 ng/mL 3. 4-ANPP 0.65 ng/mL 4. Methamphetamine 19 ng/mL 5. 11-Hydroxy Delta-9 THC 1.2 ng/mL; Delta-9 Carboxy THC 42 ng/mL; Delta-9 THC 2.9 ng/mL 6. Cotinine positive 7. Caffeine positive B. Blood volatiles: negative for ethanol, methanol, isopropanol, or acetone C. Urine drug screen: presumptive positive for cannabinoids, amphetamines, and fentanyl/metabolite D. Urine drug screen confirmation: morphine (free) 86 ng/mL  https://www.hennepin.us/-/media/hennepinus/residents/public-safety/documents/Autopsy_2020-3700_Floyd.pdf