HCQ plus zinc works to mitigate the massive viral replication which then leads to the cytokine storm which creates the dangerous aspect of the disease.  Of course it will not help after the initial phase of viral replication. It is of little use if used late and these "negative studies" simply emphasize that.  Fauci is not a clinician.  He has no clue of the need for early treatment? or, is it because he (like the Lancet) are co-opted by big Pharma.  AKA Darth Vader of the medical world.