The mechanisms how HCQ and zinc work against SARS-CoV-2 entering the cells and against the replication of the virus RNA inside the cell are very well understood.  What is missing are the double blind studies that give us the numbers: how many people must be treated with HCQ and zinc to save a life (for comparison: 38 for Remdesivir), and how many days after the infection are HCQ and zinc useful (when the patient is in the ICU, the virus load does not matter anymore). These studies have been disrupted after a company with an adult actor managed to place a fake study that seemed to show that HCQ is deadly. Other studies used overdoses of the 5 times more potent Chloroquine to proof that HCQ could be dangerous too. Not all of these studies are retracted already, so don't expect to see neutral (non politicized) studies soon. But that doesn't stop doctors to use HCQ and zinc to treat their patients, so anecdotal evidence is adding up.