Interesting post.  I worked in a malaria infested country and took fansidar from which I suffered crazy side affects. To the point where I went and had my brain scanned from the exp  209  eriences that I was having.  It was not until after I quit the med that the affect subsided.  There are also serious side affects from HCQ and people that take it on a regular basis live about 10 years less than the average person.  So there are side affects.  It is not perfect.