Yeah I have run into the Vanity sizing as a fucking man.  I tried to buy clothes recently after losing a lot of weight from an illness, doctors are trying to curb it so I don't lose anymore. Anyways I got a size that was like 1 down from where I was before in the waste...didn't fit.  Had to go down another size.  Shirts were also a size too big.  It scared me cause I thought I might have cancer since it seemed like I had lost alot more than I have. My mom's cancer basically became known because of her rapid weight loss.