Since satiety is largely due to stretch of the stomach and people tend to eat a consistent weight of food, increasing food volume and mass increases satiety.  There's already a miraculous and readily available chemical which can be used for this purpose.  It's commonly known as fucking water.  There are also these things called vegetables which have a high nutrient density and a low caloric density, which reminds me of another miracle substance called motherfucking fiber. Hoooooooooooly shit.  The rage in me is real right now, people.  I can't.  I just can't.  I mean, all the food these bariatric shit stains need to nourish and satisfy them is literally growing from the earth and they'd actually rather consider putting fucking PTFE in their food instead because it might allow them to keep eating disgusting slop without blowing up like Violet from Willy Wonka and the Chocolate Factory.