it's an issue for trans people, not for these crybabies or for people who aren't trans. for actual trans people, it can cause dysphoria and make them feel depressed because it means they aren't 'passing' as the gender they feel they are. when tumblr fats who were born women, dress stereotypically feminine, have feminine names, etc. get upset that people call them 'she' it just makes no fucking sense. it's an honest mistake. you were born a woman and you are giving off every possible signal that you're a woman. why would anyone magically guess that you identify as a my little pony/pokemon or whatever? there are some trans people who don't want to conform to rigid gender standards (such as, say, a person born male who transitions to female, but wants to be a woman who has short hair and wears pants. and that's fine! there are plenty of people born female who have short hair and wear pants!), and none of them that i've ever met or worked with gets upset about misgendering.