For me, however, it does regulate my mood, as I was extremely depressed when not taking the medication  I really think this is the base of it. When I'm undermedicated, even if I go to the gym... I just don't put 100% in. I become "blah". Therefore, I'm not running as fast, decreasing my total distance in the session.  And I swear by the whole "decreased BMR" thing. This Christmas, I'm getting mine tested.