Losing arms, not usually. Fingers, sometimes. BUT the good news is that left upper arm is a great spot for the eventual arterial-venous fistulas they'll need when they've finally abused their kidneys into oblivion and need weekly dialysis! Or if the legs start to go before the kidneys do, they might need to get some arm vein harvested to replace their diseased femoral arteries, make some great scarring through those tats.