I doubt even that. maybe if it hits her just right, but she would need to let him. as an mma fighter myself, i can say that its pretty easy to not get hit by fatties. Im 155-160lbs at 5'9" and spar 200-220lb 6' people at my gym, and they are always slower than me. one good hit from them and im down, but it doesnt happen often because of speed and technique. she could easily out cardio him, and would probably be able to do enough damage to win. she is a woman, but she has some muscle on her, and with her good technique she could probably do him in.  then again maybe not, never know until it happens haha.