They just don't seem to ever realize that being fat makes everything worse.  I also live with life-long pain.  It sucks, I know.  But I can only imagine how much worse it would be with an extra 300lbs to carry around all day, every day. Really the best way to combat any disease is to be as healthy and fit as you can be.  It even helps with mental issues (for a variety of reasons). And all they have to do is put down the donuts.