Growing up, we had a neighboring family with a daughter about my age and a son that was a bit older.   He found out he was diabetic (type 1) in his mid teens. He never took it seriously.    When he was in his early 20's he went out partying. On his way home he had a seizure, and veered into oncoming traffic. He hit a truck head on.   He woke up missing his left arm above the elbow. He also had noticeable brain damage.