That's a Pulitzer Award winning novel if I ever heard of it! I do remember from somewhere though, there's this movie that features sever horror shorts. One of them is an overweight woman who is so fed up with being such a lardass that she takes a knife and cuts it all off. She's a skinny bloody mess at the end. But IIRC, she's a happy, skinny bloody mess who just dies. Don't recall the name though.