Hormone replacement therapy. Basically mentally ill people who will have at least a 45% chance of killing themselves get hormones from doctors to "become" something they will never be, i.e. try to change "gender", then proceed to fuck their entire brains and bodies up more.  Here's the catch the doctors distributing this stuff don't like you telling these mentally ill people: every cell in your body indicates by chromosomes whether you are male or female, no matter how much you butcher up your dick or hormones you take, you will have XX or XY chromosomes. A lot of these people who should have got mental halp end up figuring this out too late, and end up committing suicide.