Non-fat with "Fat Disease" This moronic article is brought to you from the New York Times A lady, Ms. Johnson, is 5 feet 7 and 119 pounds (so BMI 18.6 or .1 away from being considered underweight) She was experiencing health issues, so she went to the doctor who did some tests, and she was diagnosed with Lipodystrophy. Leptin is released by fat cells and travels through the blood to the brain. The more fat on a person’s body, the more leptin is released. When fat levels are low, leptin levels in the brain are low, and the brain responds by increasing the person’s appetite, prompting the person to eat and gain weight. For someone like Ms. Johnson, who has almost no fat cells to signal the brain, the brain gets almost no leptin. To the brain, it seems as if she is starving. As a result, she receives continuous signals to eat. With leptin treatment, Ms. Johnson’s brain was tricked into responding as though she had abundant fat. Her insatiable hunger vanished. Fat disappeared from her liver, her blood glucose became normal, and so did her cholesterol and triglyceride levels. But why did she and other lipodystrophy patients have these conditions in the first place, and why did they vanish? What was going on? Of course nobody asked her how much she actually ate. What is a snack to a fatty can be more than many people eat in a day. Likewise, what is a lot to some people might be a small meal to someone even at a normal BMI. If someone grew up eating small meals due to poverty or has a different cultural background - Ms. Johnson was born outside the USA - it might skew why "No matter how much she ate, she never gained weight." And the big (teehee) thing that popped out at me was why nobody asked her "Do you eat when you are hungry?" It's like they assumed just because someone is hungry that they are gonna eat! Reeeeeeeetarded! And check out this fucking fat logic. From a doctor. FFS. “It is so accepted that obesity is bad for you, but why is it bad for you?” Dr. Virtue says. “If I put a 50-pound weight on your back and asked you to walk around all day, you would be a superhealthy person.”