I gained weight while taking Seroquel (for anti-anxiety and sleep). But that wasn't because of the medication itself- I was zoning out, like a zombie, and packing away pizza and other shit that I normally wouldn't. I gained around 7-10 pounds before I decided to deal with my anxiety with another method or drug. I don't understand how some people think just popping a pill and not eating any differently will make them gain weight. I fully admit that it was the shit I was eating while on the drug and not the drug itself- either deal with it, and if you can't, switch medications because that one isn't working for you.