My mom was obese (not sure weight/BMI based on photos, may have been morbid as she definitely is at least class II now) with myself and two younger sisters, and I'm somewhere on the spectrum with a fuckload of anxiety issues and ADHD. My stepkids' mom was/is morbidly obese (possibly also class II) and the daughter has some very odd social problems and anxiety, nothing diagnosed; the son has ADHD and may be on the spectrum somewhere too.  Actually they both might be.  She also smoked the entirety of both of her pregnancies.