"It affects no one but themselves." Tell that to my back and my colleagues you fat fuck. And sure, there are some medicine and medical conditions that can cause weight gain. I've worked with people who have that. Hell, one of my coworkers have PCOS. But you know what? SHE DOESN'T WEIGHT 400 LBS! I'm not saying she's not fat, cause she is. I estimate she weighs around 200, and that's PCOS combined with the fact that she cba training or maintaining a diet. But no medicine, no condition will cause someone to become so fat they 1) can't wipe themselves 2) they're bedridden. End. Of.