muh guhnetiks - some people weigh more than others when their diets are high in saturated fat Hi everyone, I'm on 23&me and get occasional updates about my genetics, and the latest one is relevant. Best to stay ahead of this one before the fatties find it and use it as a lame counter to CICO. Unfortunately I can't link to it since it's behind a 23&me login, but it can be found under the wellness reports if anyone else here is a member. I'll report the relevant bits here, instead: People with your genetic result tend to have a similar BMI on diets with greater or less than 22 grams of saturated fat per day, as long as they consume the same number of total calories. In addition to diet and exercise, genetics plays a role in determining your body weight. People with two copies of the variant in this report tend to weigh more on a high saturated fat diet. This [rs5082] variant is near a gene called APOA2, which contains instructions for making a protein called apolipoprotein A-II (apo A-II). People with two copies of the variant produce less apo A-II protein than people with zero or one variant. Scientists are working to understand how apo A-II affects our body’s response to saturated fat. 2 variants (GG) Likely to weigh more on a diet high in saturated fat 1 variant (AG) Likely similar weight on diets high or low in saturated fat 0 variants (AA) Likely similar weight on diets high or low in saturated fat  They also have a link to a breakdown of these variants for different racial groups: Takeaway?