I think it depends on when you find out that you are infertile. I'm most likely infertile but found it out quite early before even having the right partner, so it was really easy for me to come to terms with that. However I do have friends who found it out after trying for a while who really dreamt about having a child for a long time. It's really hard for them to handle it, especially after investing thousands of euros in fertility treatment and always being full of hope just to get disappointed.