(Possibly) How & Why Being Fat Fucks Up your Brain There's growing evidence that being fat increases a person's risk for developing demetias, especially alzheimer's disease. There's also growing evidence that intermittent fasting is not only good for your health and longevity, it also gives a person some protection against dementias (which is of especial importance for people like me, cursed with a genetic/familial propensity towards the disease. This article gives a possible reason why , and it describes an ongoing study (in humans, not mice!) that's worth watching : ...Before the rise in agriculture, when people were still hunting for food, they often went long periods without eating. Over time, evolution favored those who could survive without their beloved breakfasts (and lunches and dinners)....We now know that we use the glucose we get from foods, particularly carbohydrates, to fuel our bodies. We use this fuel, called glycogen, for about 12 hours after we eat. When it runs out, our bodies switch to an alternate energy source — ketone bodies.Produced by the liver during periods of fasting and low carbohydrate intake, ketones also fuel our organs, including the brain. In the brain, much of this energy goes to our neurons. But while both glycogen and ketones fuel our neurons, higher ketone production has been linked to improved thinking, learning and memory. Some scientists theorize that ketones provide neurons with more energy than glycogen does, and with this extra energy, the neurons can better ward off cell death and brain degradation in the long term.  But with early breakfasts and late-night snacking, the standard American diet prevents us from making that metabolic switch from glycogen to ketones... we could be starving our brains of the fuel they need to live a long, healthy life.... IOW, people who canNOT stop eating for 15 freakin' minutes, who lie to themselves about their caloric intake (on the rare occasions they pretend to count calories), and who think that every little sensation in their "tummies" is a hunger pang, which  "proves" they've gone into 'starvation mode' and it's time to shovel in another 400-500 calories, lest their enormous shambling carcasses "hold on" to calories, AND when all their FA/HAES bullshit makes them grow ever larger, ever less human in appearance,  they don't think this disproves the aforementioned bullshit, but rather proves their "genetics" are somehow faulty...These people are not only ruining their bodies, they're probably  destroying their brains.  The rest of the article is available at the links below ; the article does have links to other articles and possibly to the studies themselves. At one time, you could comment on the article, but for some reason, the comments are not only closed, they seem to have been deleted entirely. Gee, I wonder why that was done? /s    The Growing Science Behind a Fasting Treatment for Alzheimer’s Archive link