Guns, germs and steel... The germs in-particular come from livestock, Eurasia being a large piece of land where crops and livestock could thrive and be traded very var across longitude, because of the common latitude.  You have the fist livestock in Eurasia and by extension the most disease and immunity to said disease.  We can even see it today as the new flu strain makes its way out of the hen houses in China yearly. The rest is the same ol' shit that's been going down since the dawn of microbial life a fight for life and resources... There was a lot of horrible genocidal shit done throughout human history. The trail of tears and associated shit is a terrible stain on America but tribes weren't averse to warfare before whitey arrived either. War is as old as civilization itself. Is it not enough to live with my own transgressions upon nature/humanity must I also bear the weight of every conquistador in the Spanish army? Every salve trader in the South?  The countless South Americans who had their regimes destabilized? The deformed kids in Cambodia?....  How about we all be responsible for our own actions instead of flagellating ourselves over the greed of some aristocrat, somewhere at some point who was also a white guy. You should feel more responsible for the sad life of the kid (and practical slave) who made your iPhone than a slave who tended fields thousands of miles away and who lived and died long before you were born.