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"type": "personal" } }, { "person_or_org": { "family_name": "Karl\u00f3cai", "given_name": "Krist\u00f3f", "name": "Karl\u00f3cai, Krist\u00f3f", "type": "personal" } }, { "person_or_org": { "family_name": "Gali\u00e8", "given_name": "Nazzareno", "name": "Gali\u00e8, Nazzareno", "type": "personal" } }, { "person_or_org": { "family_name": "Degano", "given_name": "Bruno", "name": "Degano, Bruno", "type": "personal" } }, { "person_or_org": { "family_name": "Bonderman", "given_name": "Diana", "name": "Bonderman, Diana", "type": "personal" } }, { "person_or_org": { "family_name": "Kurzyna", "given_name": "Marcin", "name": "Kurzyna, Marcin", "type": "personal" } }, { "person_or_org": { "family_name": "Efficace", "given_name": "Michela", "name": "Efficace, Michela", "type": "personal" } }, { "person_or_org": { "family_name": "Giorgino", "given_name": "Ruben", "name": "Giorgino, Ruben", "type": "personal" } }, { "person_or_org": { "family_name": "Lang", "given_name": "Irene M.", "name": "Lang, Irene M.", "type": "personal" } } ], "description": "In this phase 2 proof-of-concept study we examined the safety and efficacy of selexipag, an orally available, selective prostacyclin receptor (IP receptor) agonist, as a treatment for pulmonary arterial hypertension (PAH).43 adult patients with symptomatic PAH (receiving stable endothelin receptor antagonist and/or a phosphodiesterase type-5 inhibitor therapy) were randomised three to one to receive either selexipag or placebo. 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