SIB Swiss Institute of Bioinformatics - Biodata Resources
Published September 11, 2023 | Version neXtProt data release 2023-09-11
Dataset Open

neXtProt Data release 2023-09-11

Creators

  • 1. ROR icon SIB Swiss Institute of Bioinformatics

Description

neXtProt is a comprehensive human-centric discovery platform, offering its users a seamless integration of and navigation through protein-related data.

Developed between 2009 and 2023 by the CALIPHO group (Computer Analysis and Laboratory Investigation of Proteins of Human Origin) at the University of Geneva and the SIB Swiss Institute of Bioinformatics, neXtProt was designed to help researchers make sense of what all these human proteins do in our bodies by 

  • Adding more information to the corpus of data on human proteins that is already in Swiss-Prot with data originating from a variety of high-throughput approaches (such as micro-array, antibodies screens, proteomics, interactomics, structural genomics).
  • Carefully selecting all of these data sets to provide high-quality data.
  • Organizing the data in such a way that it is possible to seamlessly build powerful queries in the most user-friendly way possible.
  • Developing software tools ranging from sequence analysis to text and data mining to be integrated in various research environments. These tools will meet the specific needs of both academic and industrial users.

Files

Files (13.4 GB)

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md5:18c4b57e23b347aa95926eaf1b371b8b
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Additional details

Funding

SIB Swiss Institute of Bioinformatics

Dates

Submitted
2024-11-26
Deposited in Zenodo

Software

Repository URL
https://github.com/calipho-sib

References

  • Zahn-Zabal M, Michel PA, Gateau A, Nikitin F, Schaeffer M, Audot E, Gaudet P, Duek PD, Teixeira D, Rech de Laval V, Samarasinghe K, Bairoch A, Lane L. The neXtProt knowledgebase in 2020: data, tools and usability improvements. Nucleic Acids Res. 2020 Jan 8;48(D1):D328-D334. doi: 10.1093/nar/gkz995. PMID: 31724716; PMCID: PMC7145669
  • Adhikari S, Nice EC, Deutsch EW, Lane L, et al. A high-stringency blueprint of the human proteome. Nat Commun. 2020 Oct 16;11(1):5301. doi: 10.1038/s41467-020-19045-9.