| Concentration in the clotting mixture [mg/mL] | Crude extract | Methanol fraction | Aqueous fraction | |||
|---|---|---|---|---|---|---|
| Results are presented as the mean of 6 measurements ± SD and analysed with one-way ANOVA followed by Dunnett's test. * P <.05, ** P <.001. Crude extract, methanol fraction, aqueous fraction vs. control. | ||||||
| APTT | PT | APTT | PT | APTT | PT | |
| Control | 15.35 ± 0.03 | 14.17 ± 0.01 | 15.35 ± 0.03 | 14.25 ± 0.02 | 15.35 ± 0.03 | 14.32 ± 0.06 |
| 0.18 | 14.93 ± 0.02* | 14.07 ± 0.02* | 14.51 ± 0.01** | 14.16 ± 0.01 | 14.55 ± 0.01** | 14.23 ± 0.01* |
| 0.36 | 14.04 ± 0.00* | 13.36 ± 0.01** | 13.98 ± 0.01** | 13.46 ± 0.02** | 14.02 ± 0.01** | 13.52 ± 0.02** |
| 0.71 | 13.22 ± 0** | 12.75 ± 0.02** | 13.15 ± 0.01** | 12.83 ± 0.01** | 13.19 ± 0.01** | 12.9 ± 0.01** |
| 1.43 | ND | ND | 12.96 ± 0.03** | ND | 13.00 ± 0.03** | ND |
| 2.86 | ND | ND | ND | ND | ND | ND |
| 5.71 | ND | ND | ND | ND | ND | ND |
| 11.43 | ND | – | ND | – | ND | – |