ENSG,Name,Class,Type,core/var,Disease causing,Tissue,
ENSG00000197785,ATAD3A,Autophagy substrate selection,Mitophagy,core,yes,"Brain, Muscle - Skeletal",
ENSG00000171608,PIK3CD,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Multisystem,
ENSG00000054523,KIF1B,Autophagosome closure maturation and lysosome fusion,HOPS-BORC interaction mediator,variable,yes,Nerve,
ENSG00000198793,MTOR,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Brain,
ENSG00000116688,MFN2,Autophagy substrate selection,Mitophagy,variable,yes,Nerve,
ENSG00000048707,VPS13D,Autophagy substrate selection,nan,variable,yes,Brain,
ENSG00000159363,ATP13A2,Pre-initiation autophagy signaling,mTORC1 signal integration,variable,yes,Brain,
ENSG00000127472,PLA2G5,Lysosomal catabolism,Lysosomal phospholipase,variable,yes,Eye,
ENSG00000158828,PINK1,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000179163,FUCA1,Lysosomal catabolism,Lysosomal fusocidase,variable,yes,Multisystem,
ENSG00000131238,PPT1,Lysosomal catabolism,Lysosomal de-palmitoylation,variable,yes,Brain,
ENSG00000198198,SZT2,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Brain,
ENSG00000116678,LEPR,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Addipose tissue,
ENSG00000142875,PRKACB,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,Heart,
ENSG00000065135,GNAI3,Pre-initiation autophagy signaling,nan,variable,yes,"Ear, Head",
ENSG00000156171,DRAM2,Autophagosome closure maturation and lysosome fusion,nan,variable,yes,Eye,
ENSG00000134242,PTPN22,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Whole Blood,
ENSG00000213281,NRAS,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Multisystem,
ENSG00000143387,CTSK,Lysosomal catabolism,Lysosomal protease,variable,yes,Bone,
ENSG00000143575,HAX1,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Whole Blood,
ENSG00000177628,GBA,Lysosomal catabolism,Lysosomal sphingomyelin/ceramide metabolism,variable,yes,"Whole Blood, Liver, Spleen, Brain",
ENSG00000116586,LAMTOR2,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Whole Blood,
ENSG00000143222,UFC1,Autophagy substrate selection,ERphagy,core,yes,Brain,
ENSG00000118217,ATF6,Autophagy gene expression,Transcription factor,variable,yes,Eye,
ENSG00000116903,EXOC8,Autophagophore initiation and elongation,Modulator of ULK1 complex assembly,variable,yes,Brain,
ENSG00000171853,TRAPPC12,Autophagophore initiation and elongation,TRAPP complex component,variable,yes,Brain,
ENSG00000134324,LPIN1,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Kidney,
ENSG00000055332,EIF2AK2,Autophagy gene expression,Inflammation related autophagy regulation,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000138095,LRPPRC,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Multisystem,
ENSG00000115355,CCDC88A,Pre-initiation autophagy signaling,nan,variable,yes,Brain,
ENSG00000116039,ATP6V1B1,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Kidney,
ENSG00000144036,EXOC6B,Autophagophore initiation and elongation,Modulator of ULK1 complex assembly,variable,yes,Multisystem,
ENSG00000115317,HTRA2,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,core,yes,"Whole Blood, Bone Marrow",
ENSG00000172071,EIF2AK3,Autophagy gene expression,ER stress signaling pathway,variable,yes,Multisystem,
ENSG00000116044,NFE2L2,Autophagy gene expression,Transcription factor,variable,yes,Multisystem,
ENSG00000115415,STAT1,Autophagy gene expression,nan,variable,yes,Whole Blood,
ENSG00000115020,PIKFYVE,Autophagosome closure maturation and lysosome fusion,PIKFYVE complex component,variable,yes,Eye,
ENSG00000115592,PRKAG3,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,Muscle - Skeletal,
ENSG00000036257,CUL3,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,"Brain, Vasculature",
ENSG00000169047,IRS1,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Multisystem,
ENSG00000085978,ATG16L1,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Colon,
ENSG00000150995,ITPR1,Pre-initiation autophagy signaling,"AMPK signaling pathway, upstream",variable,yes,Brain,
ENSG00000163719,MTMR14,Autophagophore initiation and elongation,Regulation of PI3P levels,variable,yes,Muscle - Skeletal,
ENSG00000132155,RAF1,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Multisystem,
ENSG00000170266,GLB1,Lysosomal catabolism,Lysosomal galactosidase,variable,yes,"Lung, Whole Blood, Bone Marrow",
ENSG00000168036,CTNNB1,Autophagy gene expression,Repressor of TCF7L2 activity,variable,yes,"Brain, Kidney",
ENSG00000011198,ABHD5,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Liver, Whole Blood, Bone Marrow",
ENSG00000163820,FYCO1,Autophagosome closure maturation and lysosome fusion,Movement of autophagosomes along microtubules,variable,yes,Eye,
ENSG00000114378,HYAL1,Lysosomal catabolism,Lysosomal hyaluronidase,variable,yes,Muscle - Skeletal,
ENSG00000114388,NPRL2,Pre-initiation autophagy signaling,Nutrient sensing,core,yes,Brain,
ENSG00000163932,PRKCD,Autophagophore initiation and elongation,Hypoxia signaling pathway,variable,yes,"Whole Blood, Kidney, Bone Marrow",
ENSG00000083937,CHMP2B,Autophagosome closure maturation and lysosome fusion,ESCRT-III complex component,variable,yes,Brain,
ENSG00000114573,ATP6V1A,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,"Brain, Skin (connective tissue)",
ENSG00000081307,UBA5,Autophagy substrate selection,ERphagy,variable,yes,Brain,
ENSG00000075651,PLD1,Lysosomal catabolism,Lysosomal phospholipase,variable,yes,Heart,
ENSG00000121879,PIK3CA,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Breast, Brain, Artery, Skin, Colon, Liver, Lung,  Ovary",
ENSG00000181449,SOX2,Autophagy gene expression,Transcription factor,variable,yes,Eye,
ENSG00000114867,EIF4G1,Autophagy gene expression,nan,variable,yes,Brain,
ENSG00000073282,TP63,Autophagy gene expression,Transcription factor,variable,yes,Multisystem,
ENSG00000198836,OPA1,Autophagy substrate selection,nan,variable,yes,"Brain, Heart, Eye",
ENSG00000145016,RUBCN,Autophagosome closure maturation and lysosome fusion,Class 3 PI3K complex 2 component,variable,yes,Brain,
ENSG00000127415,IDUA,Lysosomal catabolism,Lysosomal iduronidase,variable,yes,Lung,
ENSG00000197386,HTT,Autophagosome closure maturation and lysosome fusion,Retrograde transport along axons,variable,yes,Brain,
ENSG00000007062,PROM1,Pre-initiation autophagy signaling,Miscellaneous mTORC1 regulation,variable,yes,Eye,
ENSG00000154277,UCHL1,Autophagophore initiation and elongation,Deubiquitination of ATG8 homologs,variable,yes,Brain,
ENSG00000128052,KDR,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Skin, Vasculature",
ENSG00000138674,SEC31A,Autophagophore initiation and elongation,ER membrane input,core,yes,Brain,
ENSG00000163625,WDFY3,Autophagy substrate selection,Aggrephagy,variable,yes,Brain,
ENSG00000109320,NFKB1,Autophagy gene expression,Component of NFkB transcription factor,variable,yes,Lung,
ENSG00000109323,MANBA,Lysosomal catabolism,Lysosomal mannosidase,variable,yes,Multisystem,
ENSG00000145354,CISD2,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Multisystem,
ENSG00000150961,SEC24D,Autophagophore initiation and elongation,ER membrane input,variable,yes,Bones,
ENSG00000172007,RAB33B,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Multisystem,
ENSG00000038002,AGA,Lysosomal catabolism,Lysosomal protein deglycosidase,variable,yes,"Whole Blood, Bone Marrow",
ENSG00000168538,TRAPPC11,Autophagophore initiation and elongation,TRAPP complex component,core,yes,Muscle - Skeletal,
ENSG00000151729,SLC25A4,Autophagy substrate selection,Mitophagy,variable,yes,Muscle - Skeletal,
ENSG00000154153,FAM134B,Autophagy substrate selection,ERphagy,variable,yes,Nerve,
ENSG00000145675,PIK3R1,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Lung, Whole Blood, Bone Marrow",
ENSG00000049860,HEXB,Lysosomal catabolism,Lysosomal hexosaminidase,variable,yes,Brain,
ENSG00000113273,ARSB,Lysosomal catabolism,nan,variable,yes,"Heart, Brain, Nerve",
ENSG00000113368,LMNB1,Autophagy substrate selection,Nucleophagy,variable,yes,Brain,
ENSG00000169194,IL13,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Whole Blood, Lung, Eye",
ENSG00000113575,PPP2CA,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,Multisystem,
ENSG00000152700,SAR1B,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Intestine,
ENSG00000196743,GM2A,Lysosomal catabolism,Lysosomal hexosaminidase,variable,yes,Brain,
ENSG00000161011,SQSTM1,Autophagophore initiation and elongation,nan,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000137275,RIPK1,Autophagophore initiation and elongation,ER stress signaling pathway,variable,yes,"Lung, Whole Blood, Bone Marrow",
ENSG00000204435,CSNK2B,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,core,yes,Brain,
ENSG00000204386,NEU1,Lysosomal catabolism,Lysosomal sialidase,variable,yes,"Whole Blood, Bone Marrow",
ENSG00000096060,FKBP5,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Brain, Nerve",
ENSG00000095970,TREM2,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,variable,yes,"Brain, Bone",
ENSG00000112210,RAB23,Autophagy substrate selection,Xenophagy,variable,yes,Brain,
ENSG00000196586,MYO6,Autophagosome closure maturation and lysosome fusion,Movement of autophagosomes along actin,variable,yes,Ear,
ENSG00000135317,SNX14,Autophagosome closure maturation and lysosome fusion,nan,variable,yes,Brain,
ENSG00000135341,MAP3K7,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",core,yes,"Heart, Brain",
ENSG00000057663,ATG5,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Brain,
ENSG00000112367,FIG4,Autophagosome closure maturation and lysosome fusion,PIKFYVE complex component,variable,yes,"Brain, Nerve, Whole Blood, Bone Marrow",
ENSG00000152661,GJA1,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Heart,
ENSG00000118503,TNFAIP3,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,variable,yes,Whole Blood,
ENSG00000055208,TAB2,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Heart,
ENSG00000157954,WIPI2,Autophagophore initiation and elongation,ATG2-WIPI complex component,core,yes,Brain,
ENSG00000011275,RNF216,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Brain,
ENSG00000136238,RAC1,Chaperone directed autophagy,Substrate delivery,variable,yes,Brain,
ENSG00000106460,TMEM106B,Lysosomal catabolism,Lysosomal acidification,variable,yes,Brain,
ENSG00000136244,IL6,Pre-initiation autophagy signaling,Inhibition of apoptosis by caspase-8 inhibition,variable,yes,Whole Blood,
ENSG00000146648,EGFR,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Lung,
ENSG00000169919,GUSB,Lysosomal catabolism,Lysosomal glucuronidase,variable,yes,Multisystem,
ENSG00000170027,YWHAG,Autophagy gene expression,Modulator of TFEB activity,variable,yes,Brain,
ENSG00000105854,PON2,Lysosomal catabolism,Lysosomal arylesterase,variable,yes,Vasculature,
ENSG00000174697,LEP,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Addipose tissue,
ENSG00000105929,ATP6V0A4,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Kidney,
ENSG00000106462,EZH2,Autophagy gene expression,Suppressor of autophagy gene transcription,variable,yes,Bone,
ENSG00000164885,CDK5,Autophagosome closure maturation and lysosome fusion,nan,variable,yes,Brain,
ENSG00000106617,PRKAG2,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,Heart,
ENSG00000136574,GATA4,Autophagy gene expression,Transcription factor,variable,yes,"Heart, Testis",
ENSG00000155975,VPS37A,Autophagosome closure maturation and lysosome fusion,ESCRT-I complex component,variable,yes,Brain,
ENSG00000104763,ASAH1,Lysosomal catabolism,Lysosomal sphingomyelin/ceramide metabolism,variable,yes,Multisystem,
ENSG00000147416,ATP6V1B2,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Multisystem,
ENSG00000104365,IKBKB,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,Whole Blood,idan - lung
ENSG00000165102,HGSNAT,Lysosomal catabolism,Lysosomal heparin acetyltransferase to prepare for heparin degradation,variable,yes,Multisystem,
ENSG00000023287,RB1CC1,Autophagophore initiation and elongation,ULK1 complex component,variable,yes,Breast,
ENSG00000137055,PLAA,Autophagy substrate selection,Lysophagy,variable,yes,Brain,
ENSG00000147894,C9orf72,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,Brain,
ENSG00000107201,DDX58,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Multisystem,
ENSG00000165006,UBAP1,Autophagosome closure maturation and lysosome fusion,ESCRT-I complex component,variable,yes,Muscle - Skeletal,
ENSG00000165280,VCP,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Muscle - Skeletal, Nerve, Brain",
ENSG00000165059,PRKACG,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,"Whole Blood, Bone Marrow",
ENSG00000148356,LRSAM1,Autophagy substrate selection,Xenophagy,variable,yes,Nerve,
ENSG00000165699,TSC1,Pre-initiation autophagy signaling,mTORC1 signal integration,variable,yes,"Brain, Skin, Heart, Lung, a lot",
ENSG00000148384,INPP5E,Autophagosome closure maturation and lysosome fusion,nan,variable,yes,Brain,
ENSG00000123240,OPTN,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000107897,ACBD5,Autophagy substrate selection,Pexophagy,variable,yes,Brain,
ENSG00000095787,WAC,Autophagophore initiation and elongation,nan,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000148672,GLUD1,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Pancreas,
ENSG00000171862,PTEN,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Multisystem,
ENSG00000107798,LIPA,Lysosomal catabolism,Lysosomal lipase,variable,yes,Multisystem,
ENSG00000213341,CHUK,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,"Multisystem, Skin",
ENSG00000077150,NFKB2,Autophagy gene expression,Component of NFkB transcription factor,variable,yes,Whole Blood,
ENSG00000108061,SHOC2,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,core,yes,Multisystem,
ENSG00000148737,TCF7L2,Autophagy gene expression,Transcription factor,variable,yes,Multisystem,
ENSG00000151929,BAG3,Chaperone directed autophagy,Substrate delivery,variable,yes,"Heart, Muscle - Skeletal",
ENSG00000174775,HRAS,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Multisystem,
ENSG00000117984,CTSD,Lysosomal catabolism,Lysosomal protease,variable,yes,Brain,
ENSG00000166311,SMPD1,Lysosomal catabolism,Lysosomal sphingomyelin/ceramide metabolism,variable,yes,Multisystem,
ENSG00000166340,TPP1,Lysosomal catabolism,Lysosomal peptidase,variable,yes,Brain,
ENSG00000133812,SBF2,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome SNARE complex regulator,variable,yes,Nerve,
ENSG00000121653,MAPK8IP1,Autophagosome closure maturation and lysosome fusion,Movement of autophagosomes along microtubules,variable,yes,Multisystem,
ENSG00000184743,ATL3,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,Nerve,
ENSG00000173039,RELA,Autophagy gene expression,Component of NFkB transcription factor,variable,yes,Whole blood,
ENSG00000172977,KAT5,Autophagophore initiation and elongation,Nutrient sensing,variable,yes,Brain,
ENSG00000174080,CTSF,Lysosomal catabolism,Lysosomal protease,variable,yes,Brain,
ENSG00000110719,TCIRG1,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Bone,
ENSG00000162341,TPCN2,Autophagophore initiation and elongation,Modulator of LRRK2 activity,variable,yes,Skin,
ENSG00000073921,PICALM,Autophagophore initiation and elongation,ATG16L1-positive plasma membrane input,variable,yes,Whole Blood,
ENSG00000109861,CTSC,Lysosomal catabolism,Lysosomal protease,variable,yes,Skin,
ENSG00000137693,YAP1,Autophagy gene expression,Cellular mechanics sensing,variable,yes,Eye,
ENSG00000149311,ATM,Pre-initiation autophagy signaling,"AMPK signaling pathway, upstream",variable,yes,"Whole Blood, Brain",
ENSG00000110324,IL10RA,Autophagy gene expression,Inflammation related autophagy regulation,variable,yes,"Intestine, Whole Blood",
ENSG00000196655,TRAPPC4,Autophagophore initiation and elongation,TRAPP complex component,core,yes,Brain,
ENSG00000160695,VPS11,Autophagosome closure maturation and lysosome fusion,HOPS complex component,core,yes,"Brain, Muscle - Skeletal",
ENSG00000110013,SIAE,Lysosomal catabolism,Lysosomal sialic acid deacetylase,variable,yes,Whole Blood,
ENSG00000139197,PEX5,Autophagy substrate selection,Pexophagy,variable,yes,Multisystem,
ENSG00000111276,CDKN1B,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,"Brain, Pancreas, Thyroid, Adrenal Gland",
ENSG00000133703,KRAS,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Multisystem,
ENSG00000087470,DNM1L,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000188906,LRRK2,Autophagophore initiation and elongation,LRRK2 itself,variable,yes,Brain,
ENSG00000111087,GLI1,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,variable,yes,Hand,
ENSG00000183735,TBK1,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,core,yes,Brain,
ENSG00000135677,GNS,Lysosomal catabolism,nan,variable,yes,Brain,
ENSG00000111537,IFNG,Autophagy gene expression,Inflammation related autophagy regulation,variable,yes,Whole Blood,
ENSG00000011465,DCN,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Eye,
ENSG00000012504,NR1H4,Autophagy gene expression,nan,variable,yes,Liver,
ENSG00000017427,IGF1,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Bone,
ENSG00000152137,HSPB8,Chaperone directed autophagy,Substrate selection,variable,yes,Nerve,
ENSG00000139719,VPS33A,Autophagosome closure maturation and lysosome fusion,HOPS complex component,variable,yes,"Heart, Whole Blood, Brain, Lung, Kidney",
ENSG00000185344,ATP6V0A2,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Skin,
ENSG00000120686,UFM1,Autophagy substrate selection,ERphagy,variable,yes,Brain,
ENSG00000185950,IRS2,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Multisystem,
ENSG00000184304,PRKD1,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Skin, Heart",
ENSG00000100906,NFKBIA,Autophagy gene expression,Inhibitor of NFkB transcription factor,variable,yes,"Skin, Whole Blood",
ENSG00000100934,SEC23A,Autophagophore initiation and elongation,ER membrane input,variable,yes,Bone,
ENSG00000072121,ZFYVE26,Autophagosome closure maturation and lysosome fusion,Modulator of class 3 PI3K complex 2 activity,variable,yes,Brain,
ENSG00000054983,GALC,Lysosomal catabolism,Lysosomal sphingomyelin/ceramide metabolism,variable,yes,Multisystem,
ENSG00000198668,CALM1,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Heart,
ENSG00000066427,ATXN3,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Brain,
ENSG00000100811,YY1,Autophagy gene expression,Modulator of TFEB activity,variable,yes,Multisystem,
ENSG00000196663,TECPR2,Autophagophore initiation and elongation,ER membrane input,variable,yes,"Brain, Nerve",
ENSG00000142208,AKT1,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Breast, Colon, Ovary, Skin, Thyroid, Uterus, Brain, Artery",
ENSG00000179364,PACS2,Autophagophore initiation and elongation,Localization of class 3 PI3K complex 1,variable,yes,Brain,
ENSG00000128829,EIF2AK4,Autophagy gene expression,Nutrient sensing,variable,yes,Vasculature,
ENSG00000104133,SPG11,Autophagic lysosome reformation,nan,variable,yes,"Nerve, Brain",
ENSG00000138592,USP8,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000103657,HERC1,Pre-initiation autophagy signaling,mTORC1 signal integration,variable,yes,Brain,
ENSG00000169032,MAP2K1,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,"Bone, Heart",
ENSG00000213614,HEXA,Lysosomal catabolism,Lysosomal hexosaminidase,variable,yes,Brain,
ENSG00000140464,PML,Autophagophore initiation and elongation,nan,variable,yes,Whole Blood,
ENSG00000140443,IGF1R,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Multisystem,
ENSG00000103148,NPRL3,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Brain,
ENSG00000103266,STUB1,Chaperone directed autophagy,Substrate selection,variable,yes,Brain,
ENSG00000103249,CLCN7,Lysosomal catabolism,Lysosomal acidification,variable,yes,Multisystem,
ENSG00000100726,TELO2,Pre-initiation autophagy signaling,Insulin signaling pathway,core,yes,Multisystem,
ENSG00000103197,TSC2,Pre-initiation autophagy signaling,mTORC1 signal integration,variable,yes,"Brain, Skin, Heart, Lung, a lot",
ENSG00000103313,MEFV,Autophagy substrate selection,Individual substrates,variable,yes,Whole Blood,
ENSG00000189067,LITAF,Autophagophore initiation and elongation,nan,variable,yes,Nerve,
ENSG00000188603,CLN3,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome interaction modulator,variable,yes,Brain,
ENSG00000178952,TUFM,Autophagy substrate selection,Mitophagy,variable,yes,Multisystem,
ENSG00000103510,KAT8,Autophagy gene expression,Suppressor of autophagy gene transcription,core,yes,Brain,
ENSG00000089280,FUS,Autophagy gene expression,nan,core,yes,Nerve,
ENSG00000167207,NOD2,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Whole Blood,
ENSG00000103043,VAC14,Autophagosome closure maturation and lysosome fusion,PIKFYVE complex component,variable,yes,Brain,
ENSG00000140968,IRF8,Autophagy gene expression,Transcription factor,variable,yes,Whole Blood,
ENSG00000141012,GALNS,Lysosomal catabolism,nan,variable,yes,Multisystem,
ENSG00000131165,CHMP1A,Autophagosome closure maturation and lysosome fusion,ESCRT-III complex component,core,yes,Brain,
ENSG00000167716,WDR81,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Brain,
ENSG00000108561,C1QBP,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,Multisystem,
ENSG00000141510,TP53,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Whole Blood, Breast, Liver, Brain, Adrenal Gland,Colon",
ENSG00000220205,VAMP2,Autophagophore initiation and elongation,ATG16L1-positive plasma membrane input,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000154803,FLCN,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,"Skin, Lung, Colon, Kidney",
ENSG00000072310,SREBF1,Autophagy substrate selection,Mitophagy,variable,yes,Skin,
ENSG00000108691,CCL2,Pre-initiation autophagy signaling,Inhibition of apoptosis by caspase-8 inhibition,variable,yes,"Heart, Whole Blood",
ENSG00000141736,ERBB2,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Nerve, Ovary, Lung, Brain",
ENSG00000168610,STAT3,Autophagy gene expression,Transcription factor,variable,yes,Whole Blood,
ENSG00000108784,NAGLU,Lysosomal catabolism,Lysosomal heparinase,variable,yes,Multisystem,
ENSG00000030582,GRN,Lysosomal catabolism,Lysosomal acidification,variable,yes,Brain,
ENSG00000131095,GFAP,Chaperone directed autophagy,Substrate delivery,variable,yes,Brain,
ENSG00000225190,PLEKHM1,Autophagosome closure maturation and lysosome fusion,Recruitment of HOPS complex to autophagosome,variable,yes,Bone,
ENSG00000266173,STRADA,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,Brain,
ENSG00000141337,ARSG,Lysosomal catabolism,nan,variable,yes,"Ear, Eye",
ENSG00000108946,PRKAR1A,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",core,yes,Multisystem,
ENSG00000182473,EXOC7,Autophagophore initiation and elongation,Modulator of ULK1 complex assembly,core,yes,Brain,
ENSG00000171298,GAA,Lysosomal catabolism,Lysosomal glucosidase,variable,yes,Multisystem,
ENSG00000181523,SGSH,Lysosomal catabolism,Lysosomal heparin sulfatase,variable,yes,Brain,
ENSG00000141551,CSNK1D,Autophagophore initiation and elongation,ER membrane input,variable,yes,Brain,
ENSG00000141580,WDR45B,Autophagophore initiation and elongation,ATG2-WIPI complex component,core,yes,Brain,
ENSG00000141458,NPC1,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome SNARE complex regulator,variable,yes,"Brain, Liver, Whole Blood",
ENSG00000152223,EPG5,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome SNARE complex regulator,variable,yes,"Brain, Skin, Heart, Whole Blood",
ENSG00000049759,NEDD4L,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,Brain,
ENSG00000171791,BCL2,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Whole Blood,
ENSG00000172270,BSG,Autophagophore initiation and elongation,Insulin signaling pathway,variable,yes,Whole Blood,
ENSG00000118046,STK11,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,"Skin,Testis, Breast, Colon, Ovary, Lung, Uterus, Thyroid",
ENSG00000126934,MAP2K2,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Multisystem,
ENSG00000127666,TICAM1,Autophagophore initiation and elongation,Signaling upstream of ATG9 localization,variable,yes,Brain,
ENSG00000090674,MCOLN1,Autophagosome closure maturation and lysosome fusion,nan,variable,yes,Brain,
ENSG00000079805,DNM2,Autophagophore initiation and elongation,Endosomal membrane input,variable,yes,"Nerve, Muscle - Skeletal",
ENSG00000102575,ACP5,Lysosomal catabolism,nan,variable,yes,"Bone, Whole Blood",
ENSG00000104774,MAN2B1,Lysosomal catabolism,Lysosomal mannosidase,variable,yes,Multisystem,
ENSG00000072062,PRKACA,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,"Adrenal Gland, Heart",
ENSG00000105647,PIK3R2,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,"Brain, Heart",
ENSG00000131943,C19orf12,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000105223,PLD3,Lysosomal catabolism,Lysosomal phospholipase,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000104856,RELB,Autophagy gene expression,Component of NFkB transcription factor,variable,yes,Whole Blood,
ENSG00000118162,KPTN,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Brain,
ENSG00000101266,CSNK2A1,Autophagophore initiation and elongation,Preparation of ATG8 homologs for lipidation,variable,yes,Brain,
ENSG00000198171,DDRGK1,Autophagy substrate selection,ERphagy,core,yes,Bone,
ENSG00000101310,SEC23B,Autophagophore initiation and elongation,ER membrane input,variable,yes,"Whole Blood, Multisystem",
ENSG00000101421,CHMP4B,Autophagosome closure maturation and lysosome fusion,ESCRT-III complex component,variable,yes,Eye,
ENSG00000197122,SRC,Autophagosome closure maturation and lysosome fusion,ATG8-LAMP1 interaction modulator,variable,yes,"Colon,Whole Blood",
ENSG00000101109,STK4,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Whole Blood,
ENSG00000064601,CTSA,Lysosomal catabolism,Lysosomal protease,variable,yes,Multisystem,
ENSG00000087586,AURKA,Pre-initiation autophagy signaling,Modulator of mTORC1 activity,variable,yes,Colon,
ENSG00000124164,VAPB,Autophagophore initiation and elongation,Localization of ULK1 complex,variable,yes,"Brain, Muscle - Skeletal",
ENSG00000101210,EEF1A2,Chaperone directed autophagy,Substrate delivery,variable,yes,Brain,
ENSG00000131100,ATP6V1E1,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Skin,
ENSG00000099940,SNAP29,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome SNARE complex,core,yes,"Brain, Skin",
ENSG00000100030,MAPK1,Pre-initiation autophagy signaling,MAPK1 signaling pathway,variable,yes,Brain,
ENSG00000100150,DEPDC5,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Brain,
ENSG00000100225,FBXO7,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000100292,HMOX1,Autophagophore initiation and elongation,Signaling upstream of ATG9 localization,variable,yes,Whole Blood,
ENSG00000100393,EP300,Pre-initiation autophagy signaling,Nutrient sensing,core,yes,"Colon, Brain",
ENSG00000198951,NAGA,Lysosomal catabolism,Lysosomal sphingomyelin/ceramide metabolism,variable,yes,Brain,
ENSG00000100299,ARSA,Lysosomal catabolism,nan,variable,yes,"Brain, Nerve",
ENSG00000101846,STS,Lysosomal catabolism,nan,variable,yes,Skin,
ENSG00000182220,ATP6AP2,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,"Brain, Whole Blood, Liver",
ENSG00000124486,USP9X,Autophagy substrate selection,Zymophagy,variable,yes,Brain,
ENSG00000102145,GATA1,Autophagy gene expression,Transcription factor,variable,yes,Whole Blood,
ENSG00000094631,HDAC6,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome interaction modulator,variable,yes,Brain,
ENSG00000068323,TFE3,Autophagy gene expression,Transcription factor,variable,yes,"Brain, Eye",
ENSG00000196998,WDR45,Autophagophore initiation and elongation,ATG2-WIPI complex component,variable,yes,Brain,
ENSG00000086758,HUWE1,Autophagy substrate selection,Mitophagy,variable,yes,Brain,
ENSG00000089289,IGBP1,Autophagophore initiation and elongation,Modulator of ULK1 activity,variable,yes,"Brain, Eye",
ENSG00000147162,OGT,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome SNARE complex regulator,variable,yes,Brain,
ENSG00000102144,PGK1,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,"Whole Blood, Brain, Muscle - Skeletal",
ENSG00000102393,GLA,Lysosomal catabolism,Lysosomal galactosidase,variable,yes,"Brain, Heart",
ENSG00000080561,MID2,Autophagy gene expression,Inflammation related autophagy regulation,variable,yes,Brain,
ENSG00000133124,IRS4,Pre-initiation autophagy signaling,Insulin signaling pathway,variable,yes,Thyroid,
ENSG00000005893,LAMP2,Autophagosome closure maturation and lysosome fusion,Lysosome-autophagosome interaction modulator,variable,yes,"Heart, Muscle - Skeletal, Brain",
ENSG00000158290,CUL4B,Autophagophore initiation and elongation,Modulator of class 3 PI3K complex 1 activity,variable,yes,Brain,
ENSG00000010404,IDS,Lysosomal catabolism,nan,variable,yes,Multisystem,
ENSG00000102030,NAA10,Pre-initiation autophagy signaling,mTORC1 signal integration,variable,yes,Multisystem,
ENSG00000071553,ATP6AP1,Pre-initiation autophagy signaling,Nutrient sensing,variable,yes,Whole Blood,
ENSG00000269335,IKBKG,Pre-initiation autophagy signaling,"AMPK signaling pathway, direct",variable,yes,"Skin, Whole Blood",
ENSG00000155961,RAB39B,Autophagophore initiation and elongation,Localization of ULK1 complex,variable,yes,Brain,