ENSG,Name,Class,Type,abs expressing tissues,core/var,disease causing ENSG00000126261,UBA2,E1 activating enzymes,nan,0,core,no ENSG00000130985,UBA1,E1 activating enzymes,nan,0,core,yes ENSG00000182179,UBA7,E1 activating enzymes,nan,8,variable,no ENSG00000033178,UBA6,E1 activating enzymes,nan,0,variable,no ENSG00000144744,UBA3,E1 activating enzymes,nan,1,variable,no ENSG00000159593,NAE1,E1 activating enzymes,nan,1,variable,no ENSG00000142230,SAE1,E1 activating enzymes,nan,0,core,no ENSG00000081307,UBA5,E1 activating enzymes,nan,1,variable,yes ENSG00000124217,MOCS3,E1 activating enzymes,nan,2,variable,no ENSG00000077721,UBE2A,E2 conjugating enzymes,UBC domain only ,2,variable,yes ENSG00000119048,UBE2B,E2 conjugating enzymes,UBC domain only ,1,variable,no ENSG00000072401,UBE2D1,E2 conjugating enzymes,UBC domain only ,5,variable,no ENSG00000131508,UBE2D2,E2 conjugating enzymes,UBC domain only ,0,core,no ENSG00000109332,UBE2D3,E2 conjugating enzymes,UBC domain only ,1,variable,no ENSG00000078967,UBE2D4,E2 conjugating enzymes,UBC domain only ,3,variable,no ENSG00000185651,UBE2L3,E2 conjugating enzymes,UBC domain only ,0,core,no ENSG00000236444,UBE2L5P,E2 conjugating enzymes,UBC domain only ,11,variable,no ENSG00000177889,UBE2N,E2 conjugating enzymes,UBC domain only ,1,variable,no ENSG00000104343,UBE2W,E2 conjugating enzymes,UBC domain only ,0,variable,no ENSG00000132388,UBE2G1,E2 conjugating enzymes,UBC domain only,2,variable,no ENSG00000184787,UBE2G2,E2 conjugating enzymes,UBC domain only,2,variable,no ENSG00000215218,UBE2QL1,E2 conjugating enzymes,UBC domain only,22,variable,no ENSG00000175063,UBE2C,E2 conjugating enzymes,UBC domain & N-terminal extension,12,variable,no ENSG00000170142,UBE2E1,E2 conjugating enzymes,UBC domain & N-terminal extension,0,core,no ENSG00000170035,UBE2E3,E2 conjugating enzymes,UBC domain & N-terminal extension,1,variable,no ENSG00000186591,UBE2H,E2 conjugating enzymes,UBC domain & C-terminal extension,0,core,no ENSG00000108106,UBE2S,E2 conjugating enzymes,UBC domain & C-terminal extension,6,variable,no ENSG00000077152,UBE2T,E2 conjugating enzymes,UBC domain & C-terminal extension,14,variable,yes ENSG00000177414,UBE2U,E2 conjugating enzymes,UBC domain & C-terminal extension,4,variable,no ENSG00000099804,CDC34,E2 conjugating enzymes,UBC domain & C-terminal extension,2,variable,no ENSG00000107341,UBE2R2,E2 conjugating enzymes,UBC domain & C-terminal extension,1,variable,no ENSG00000160714,UBE2Q1,E2 conjugating enzymes,UBC domain & RWD-like domain ,0,core,no ENSG00000140367,UBE2Q2,E2 conjugating enzymes,UBC domain & RWD-like domain ,2,variable,no ENSG00000198833,UBE2J1,E2 conjugating enzymes,UBC domain & transmembrane domain,2,variable,no ENSG00000160087,UBE2J2,E2 conjugating enzymes,UBC domain & transmembrane domain,1,variable,no ENSG00000078140,UBE2K,E2 conjugating enzymes,UBC domain & UBA domain,0,core,no ENSG00000115760,BIRC6,E2 conjugating enzymes,E2-E3 chimera,0,variable,no ENSG00000175931,UBE2O,E2 conjugating enzymes,E2-E3 chimera,0,core,no ENSG00000156587,UBE2L6,E2 conjugating enzymes,UBC domain only,3,variable,no ENSG00000182247,UBE2E2,E2 conjugating enzymes,UBC domain & N-terminal extension,2,variable,no ENSG00000159202,UBE2Z,E2 conjugating enzymes,UBC domain & N-terminal and C-terminal extensions,0,core,no ENSG00000184182,UBE2F,E2 conjugating enzymes,nan,1,variable,no ENSG00000130725,UBE2M,E2 conjugating enzymes,nan,2,variable,no ENSG00000103275,UBE2I,E2 conjugating enzymes,nan,0,core,no ENSG00000143222,UFC1,E2 conjugating enzymes,nan,0,core,yes ENSG00000114062,UBE3A,E3 ligase ,assorted,2,variable,yes ENSG00000009335,UBE3C,E3 ligase ,IQ motif,1,variable,no ENSG00000153827,TRIP12,E3 ligase ,"Armadillo-like, WW",2,variable,yes ENSG00000185345,PARK2,E3 ligase ,UBL,10,variable,no ENSG00000159459,UBR1,E3 ligase ,UBR,1,variable,yes ENSG00000024048,UBR2,E3 ligase ,UBR,3,variable,no ENSG00000162298,SYVN1,E3 ligase ,other,2,variable,no ENSG00000130939,UBE4B,E3 ligase ,UBOX,2,variable,no ENSG00000159461,AMFR,E3 ligase ,other,1,variable,no ENSG00000092098,RNF31,E3 ligase ,"RanBP2-type ZnF, PUB, UBA",1,variable,no ENSG00000103363,ELOB,E3 ligase ,CRL adaptor,0,core,no ENSG00000125826,RBCK1,E3 ligase ,"UBL, RanBP2-type ZnF",1,variable,yes ENSG00000204227,RING1,E3 ligase ,Polycomb,0,core,no ENSG00000121481,RNF2,E3 ligase ,Polycomb,0,variable,no ENSG00000168283,BMI1,E3 ligase ,Polycomb,1,variable,no ENSG00000115289,PCGF1,E3 ligase ,Polycomb,0,core,no ENSG00000277258,PCGF2,E3 ligase ,Polycomb,4,variable,yes ENSG00000185619,PCGF3,E3 ligase ,Polycomb,0,core,no ENSG00000180628,PCGF5,E3 ligase ,Polycomb,2,variable,no ENSG00000156374,PCGF6,E3 ligase ,Polycomb,1,variable,no ENSG00000276043,UHRF1,E3 ligase ,"UHRF, UBL",10,variable,no ENSG00000147854,UHRF2,E3 ligase ,"UHRF, UBL",0,variable,no ENSG00000100225,FBXO7,E3 ligase ,F-box,2,variable,yes ENSG00000130560,UBAC1,E3 ligase ,"UBL, UBA",1,variable,no ENSG00000115760,BIRC6,E3 ligase ,with intrinsic E2,0,variable,no ENSG00000175931,UBE2O,E3 ligase ,with intrinsic E2,0,core,no ENSG00000176248,ANAPC2,E3 ligase ,subunit,0,core,no ENSG00000141552,ANAPC11,E3 ligase ,subunit,1,variable,no ENSG00000153107,ANAPC1,E3 ligase ,subunit,1,variable,yes ENSG00000164162,ANAPC10,E3 ligase ,subunit,1,variable,no ENSG00000130177,CDC16,E3 ligase ,subunit,0,core,no ENSG00000094880,CDC23,E3 ligase ,subunit,0,variable,no ENSG00000004897,CDC27,E3 ligase ,subunit,0,variable,no ENSG00000089053,ANAPC5,E3 ligase ,subunit,0,core,no ENSG00000196510,ANAPC7,E3 ligase ,subunit,1,variable,no ENSG00000053900,ANAPC4,E3 ligase ,subunit,0,core,no ENSG00000176386,CDC26,E3 ligase ,subunit,0,variable,no ENSG00000129055,ANAPC13,E3 ligase ,subunit,1,variable,no ENSG00000110200,ANAPC15,E3 ligase ,subunit,0,variable,no ENSG00000166295,ANAPC16,E3 ligase ,subunit,3,variable,no ENSG00000117399,CDC20,E3 ligase ,activator,11,variable,no ENSG00000164287,CDC20B,E3 ligase ,activator,7,variable,no ENSG00000105325,FZR1,E3 ligase ,activator,0,core,no ENSG00000090316,MAEA,E3 ligase ,subunit,1,variable,no ENSG00000145916,RMND5B,E3 ligase ,subunit,2,variable,no ENSG00000153561,RMND5A,E3 ligase ,subunit,6,variable,no ENSG00000141084,RANBP10,E3 ligase ,subunit,3,variable,no ENSG00000010017,RANBP9,E3 ligase ,subunit,3,variable,no ENSG00000101193,GID8,E3 ligase ,subunit,1,variable,no ENSG00000162923,WDR26,E3 ligase ,subunit,1,variable,yes ENSG00000128585,MKLN1,E3 ligase ,subunit,0,variable,no ENSG00000160226,C21orf2,E3 ligase ,subunit,0,core,no ENSG00000114098,ARMC8,E3 ligase ,subunit,2,variable,no ENSG00000141034,GID4,E3 ligase ,subunit,3,variable,no ENSG00000119801,YPEL5,E3 ligase ,subunit,1,variable,no ENSG00000078747,ITCH,E3 ligase ,WW & C2,0,core,yes ENSG00000198742,SMURF1,E3 ligase ,WW & C2,1,variable,no ENSG00000108854,SMURF2,E3 ligase ,WW & C2,2,variable,no ENSG00000069869,NEDD4,E3 ligase ,WW & C2,8,variable,no ENSG00000049759,NEDD4L,E3 ligase ,WW & C2,14,variable,yes ENSG00000123124,WWP1,E3 ligase ,WW & C2,2,variable,no ENSG00000198373,WWP2,E3 ligase ,WW & C2,2,variable,no ENSG00000002746,HECW1,E3 ligase ,WW & C2,23,variable,no ENSG00000138411,HECW2,E3 ligase ,WW & C2,10,variable,yes ENSG00000085382,HACE1,E3 ligase ,ankyrin repeats,4,variable,yes ENSG00000092148,HECTD1,E3 ligase ,"Armadillo-like, ankyrin repeats",2,variable,no ENSG00000086758,HUWE1,E3 ligase ,"Armadillo-like, WW",1,variable,yes ENSG00000103657,HERC1,E3 ligase ,RCC1,1,variable,yes ENSG00000128731,HERC2,E3 ligase ,RCC1,1,variable,yes ENSG00000138641,HERC3,E3 ligase ,RCC1,3,variable,no ENSG00000148634,HERC4,E3 ligase ,RCC1,0,variable,no ENSG00000138646,HERC5,E3 ligase ,RCC1,8,variable,no ENSG00000138642,HERC6,E3 ligase ,RCC1,3,variable,no ENSG00000104517,UBR5,E3 ligase ,RCC1,0,core,no ENSG00000092140,G2E3,E3 ligase ,PHD-type ZnF,1,variable,no ENSG00000173064,HECTD4,E3 ligase ,SPRY,1,variable,no ENSG00000151148,UBE3B,E3 ligase ,IQ motif,1,variable,yes ENSG00000119682,AREL1,E3 ligase ,assorted,1,variable,no ENSG00000165338,HECTD2,E3 ligase ,assorted,1,variable,no ENSG00000126107,HECTD3,E3 ligase ,assorted,0,core,no ENSG00000135063,FAM189A2,E3 ligase ,ITCH-specific,13,variable,no ENSG00000131507,NDFIP1,E3 ligase ,nan,3,variable,no ENSG00000102471,NDFIP2,E3 ligase ,nan,10,variable,no ENSG00000197070,ARRDC1,E3 ligase ,nan,2,variable,no ENSG00000105643,ARRDC2,E3 ligase ,nan,6,variable,no ENSG00000113369,ARRDC3,E3 ligase ,nan,6,variable,no ENSG00000140450,ARRDC4,E3 ligase ,nan,5,variable,no ENSG00000205784,ARRDC5,E3 ligase ,nan,7,variable,no ENSG00000265972,TXNIP,E3 ligase ,nan,13,variable,no ENSG00000100387,RBX1,E3 ligase ,RBX RING,1,variable,no ENSG00000114125,RNF7,E3 ligase ,RBX RING,1,variable,no ENSG00000055130,CUL1,E3 ligase ,Cullin,2,variable,no ENSG00000108094,CUL2,E3 ligase ,Cullin,1,variable,no ENSG00000036257,CUL3,E3 ligase ,Cullin,2,variable,yes ENSG00000139842,CUL4A,E3 ligase ,Cullin,1,variable,no ENSG00000166266,CUL5,E3 ligase ,Cullin,3,variable,no ENSG00000158290,CUL4B,E3 ligase ,Cullin,0,variable,yes ENSG00000044090,CUL7,E3 ligase ,Cullin,2,variable,yes ENSG00000112659,CUL9,E3 ligase ,Cullin,0,variable,no ENSG00000151893,CACUL1,E3 ligase ,Cullin,1,variable,no ENSG00000111530,CAND1,E3 ligase ,CRL regulator,0,variable,no ENSG00000144712,CAND2,E3 ligase ,CRL regulator,9,variable,no ENSG00000174842,GLMN,E3 ligase ,CRL regulator,1,variable,no ENSG00000173163,COMMD1,E3 ligase ,CRL regulator,1,variable,no ENSG00000113558,SKP1,E3 ligase ,CRL adaptor,1,variable,no ENSG00000154582,ELOC,E3 ligase ,CRL adaptor,1,variable,no ENSG00000167986,DDB1,E3 ligase ,CRL adaptor,2,variable,no ENSG00000189091,SF3B3,E3 ligase ,CRL adaptor,0,core,no ENSG00000071894,CPSF1,E3 ligase ,CRL adaptor,2,variable,yes ENSG00000153558,FBXL2,E3 ligase ,F-box,10,variable,no ENSG00000005812,FBXL3,E3 ligase ,F-box,3,variable,yes ENSG00000182325,FBXL6,E3 ligase ,F-box,2,variable,no ENSG00000183580,FBXL7,E3 ligase ,F-box,13,variable,no ENSG00000135722,FBXL8,E3 ligase ,F-box,6,variable,no ENSG00000127452,FBXL12,E3 ligase ,F-box,1,variable,no ENSG00000171823,FBXL14,E3 ligase ,F-box,3,variable,no ENSG00000107872,FBXL15,E3 ligase ,F-box,1,variable,no ENSG00000127585,FBXL16,E3 ligase ,F-box,25,variable,no ENSG00000108306,FBXL20,E3 ligase ,F-box,0,variable,no ENSG00000177294,FBXO39,E3 ligase ,F-box,13,variable,no ENSG00000145604,SKP2,E3 ligase ,F-box,3,variable,no ENSG00000165355,FBXO33,E3 ligase ,F-box,1,variable,no ENSG00000145743,FBXL17,E3 ligase ,F-box,4,variable,no ENSG00000155034,FBXL18,E3 ligase ,F-box,3,variable,no ENSG00000112234,FBXL4,E3 ligase ,F-box,2,variable,yes ENSG00000118564,FBXL5,E3 ligase ,F-box,1,variable,no ENSG00000161040,FBXL13,E3 ligase ,F-box,5,variable,no ENSG00000163013,FBXO41,E3 ligase ,F-box,16,variable,no ENSG00000145868,FBXO38,E3 ligase ,F-box,0,core,yes ENSG00000099364,FBXL19,E3 ligase ,F-box,5,variable,no ENSG00000173120,KDM2A,E3 ligase ,F-box,1,variable,no ENSG00000089094,KDM2B,E3 ligase ,F-box,1,variable,no ENSG00000107829,FBXW4,E3 ligase ,F-box,1,variable,no ENSG00000119402,FBXW2,E3 ligase ,F-box,0,core,no ENSG00000132004,FBXW9,E3 ligase ,F-box,3,variable,no ENSG00000072803,FBXW11,E3 ligase ,F-box,2,variable,yes ENSG00000109670,FBXW7,E3 ligase ,F-box,6,variable,no ENSG00000166167,BTRC,E3 ligase ,F-box,3,variable,no ENSG00000159069,FBXW5,E3 ligase ,F-box,3,variable,no ENSG00000174989,FBXW8,E3 ligase ,F-box,0,variable,no ENSG00000241322,CDRT1,E3 ligase ,F-box,17,variable,no ENSG00000171931,FBXW10,E3 ligase ,F-box,13,variable,no ENSG00000116661,FBXO2,E3 ligase ,F-box,20,variable,no ENSG00000116663,FBXO6,E3 ligase ,F-box,3,variable,no ENSG00000269190,FBXO17,E3 ligase ,F-box,8,variable,no ENSG00000161243,FBXO27,E3 ligase ,F-box,10,variable,no ENSG00000132879,FBXO44,E3 ligase ,F-box,6,variable,no ENSG00000163444,TMEM183A,E3 ligase ,F-box,3,variable,no ENSG00000037637,FBXO42,E3 ligase ,F-box,1,variable,no ENSG00000174013,FBXO45,E3 ligase ,F-box,6,variable,no ENSG00000106336,FBXO24,E3 ligase ,F-box,2,variable,no ENSG00000118496,FBXO30,E3 ligase ,F-box,2,variable,no ENSG00000163833,FBXO40,E3 ligase ,F-box,20,variable,no ENSG00000138081,FBXO11,E3 ligase ,F-box,1,variable,yes ENSG00000147912,FBXO10,E3 ligase ,F-box,4,variable,no ENSG00000162063,CCNF,E3 ligase ,F-box,8,variable,yes ENSG00000011007,ELOA,E3 ligase ,F-box,1,variable,no ENSG00000134452,FBXO18,E3 ligase ,F-box,0,core,no ENSG00000110429,FBXO3,E3 ligase ,F-box,1,variable,no ENSG00000151876,FBXO4,E3 ligase ,F-box,0,variable,no ENSG00000112029,FBXO5,E3 ligase ,F-box,2,variable,no ENSG00000164117,FBXO8,E3 ligase ,F-box,1,variable,no ENSG00000112146,FBXO9,E3 ligase ,F-box,1,variable,no ENSG00000135108,FBXO21,E3 ligase ,F-box,1,variable,no ENSG00000167196,FBXO22,E3 ligase ,F-box,2,variable,no ENSG00000156509,FBXO43,E3 ligase ,F-box,8,variable,no ENSG00000153832,FBXO36,E3 ligase ,F-box,5,variable,no ENSG00000197361,FBXL22,E3 ligase ,F-box,15,variable,no ENSG00000214050,FBXO16,E3 ligase ,F-box,18,variable,no ENSG00000143756,FBXO28,E3 ligase ,F-box,0,variable,no ENSG00000147364,FBXO25,E3 ligase ,F-box,2,variable,no ENSG00000156804,FBXO32,E3 ligase ,F-box,15,variable,no ENSG00000141665,FBXO15,E3 ligase ,F-box,14,variable,no ENSG00000103264,FBXO31,E3 ligase ,F-box,3,variable,yes ENSG00000177051,FBXO46,E3 ligase ,F-box,2,variable,no ENSG00000178974,FBXO34,E3 ligase ,F-box,3,variable,no ENSG00000134086,VHL,E3 ligase ,VHL,1,variable,yes ENSG00000185338,SOCS1,E3 ligase ,SOCS box,14,variable,no ENSG00000120833,SOCS2,E3 ligase ,SOCS box,14,variable,no ENSG00000184557,SOCS3,E3 ligase ,SOCS box,13,variable,no ENSG00000180008,SOCS4,E3 ligase ,SOCS box,0,variable,no ENSG00000171150,SOCS5,E3 ligase ,SOCS box,2,variable,no ENSG00000170677,SOCS6,E3 ligase ,SOCS box,3,variable,no ENSG00000274211,SOCS7,E3 ligase ,SOCS box,4,variable,no ENSG00000114737,CISH,E3 ligase ,SOCS box,18,variable,yes ENSG00000065802,ASB1,E3 ligase ,SOCS box,1,variable,no ENSG00000100628,ASB2,E3 ligase ,SOCS box,22,variable,no ENSG00000115239,ASB3,E3 ligase ,SOCS box,0,variable,no ENSG00000005981,ASB4,E3 ligase ,SOCS box,20,variable,no ENSG00000164122,ASB5,E3 ligase ,SOCS box,23,variable,no ENSG00000148331,ASB6,E3 ligase ,SOCS box,1,variable,no ENSG00000183475,ASB7,E3 ligase ,SOCS box,0,variable,no ENSG00000177981,ASB8,E3 ligase ,SOCS box,1,variable,no ENSG00000102048,ASB9,E3 ligase ,SOCS box,11,variable,no ENSG00000146926,ASB10,E3 ligase ,SOCS box,16,variable,yes ENSG00000165192,ASB11,E3 ligase ,SOCS box,20,variable,no ENSG00000198881,ASB12,E3 ligase ,SOCS box,9,variable,no ENSG00000196372,ASB13,E3 ligase ,SOCS box,4,variable,no ENSG00000239388,ASB14,E3 ligase ,SOCS box,3,variable,no ENSG00000146809,ASB15,E3 ligase ,SOCS box,14,variable,no ENSG00000161664,ASB16,E3 ligase ,SOCS box,6,variable,no ENSG00000154007,ASB17,E3 ligase ,SOCS box,2,variable,no ENSG00000156381,ANKRD9,E3 ligase ,SOCS box,7,variable,no ENSG00000157999,ANKRD61,E3 ligase ,SOCS box,1,variable,no ENSG00000171621,SPSB1,E3 ligase ,SOCS box,7,variable,no ENSG00000111671,SPSB2,E3 ligase ,SOCS box,0,variable,no ENSG00000162032,SPSB3,E3 ligase ,SOCS box,4,variable,no ENSG00000175093,SPSB4,E3 ligase ,SOCS box,20,variable,no ENSG00000141542,RAB40B,E3 ligase ,SOCS box,6,variable,no ENSG00000197562,RAB40C,E3 ligase ,SOCS box,2,variable,no ENSG00000109046,WSB1,E3 ligase ,SOCS box,2,variable,no ENSG00000176871,WSB2,E3 ligase ,SOCS box,7,variable,no ENSG00000130338,TULP4,E3 ligase ,SOCS box,3,variable,no ENSG00000151743,AMN1,E3 ligase ,SOCS box,6,variable,no ENSG00000132128,LRRC41,E3 ligase ,SOCS box,0,core,no ENSG00000124257,NEURL2,E3 ligase ,SOCS box,3,variable,no ENSG00000168300,PCMTD1,E3 ligase ,SOCS box,3,variable,no ENSG00000203880,PCMTD2,E3 ligase ,SOCS box,1,variable,no ENSG00000185798,WDR53,E3 ligase ,DCAF,1,variable,no ENSG00000185658,BRWD1,E3 ligase ,DCAF,0,variable,no ENSG00000146247,PHIP,E3 ligase ,DCAF,0,variable,yes ENSG00000143164,DCAF6,E3 ligase ,DCAF,2,variable,no ENSG00000145041,DCAF1,E3 ligase ,DCAF,2,variable,no ENSG00000007168,PAFAH1B1,E3 ligase ,DCAF,0,core,yes ENSG00000122692,SMU1,E3 ligase ,DCAF,0,core,no ENSG00000103091,WDR59,E3 ligase ,DCAF,1,variable,no ENSG00000142784,WDTC1,E3 ligase ,DCAF,2,variable,no ENSG00000110497,AMBRA1,E3 ligase ,DCAF,0,variable,no ENSG00000144021,CIAO1,E3 ligase ,DCAF,0,core,no ENSG00000143207,RFWD2,E3 ligase ,DCAF,0,core,no ENSG00000119599,DCAF4,E3 ligase ,DCAF,1,variable,no ENSG00000182308,DCAF4L1,E3 ligase ,DCAF,4,variable,no ENSG00000176566,DCAF4L2,E3 ligase ,DCAF,1,variable,no ENSG00000139990,DCAF5,E3 ligase ,DCAF,1,variable,no ENSG00000136485,DCAF7,E3 ligase ,DCAF,0,core,no ENSG00000132716,DCAF8,E3 ligase ,DCAF,1,variable,yes ENSG00000189186,DCAF8L2,E3 ligase ,DCAF,2,variable,no ENSG00000122741,DCAF10,E3 ligase ,DCAF,1,variable,no ENSG00000100897,DCAF11,E3 ligase ,DCAF,3,variable,no ENSG00000198876,DCAF12,E3 ligase ,DCAF,3,variable,no ENSG00000198889,DCAF12L1,E3 ligase ,DCAF,16,variable,no ENSG00000198354,DCAF12L2,E3 ligase ,DCAF,18,variable,no ENSG00000164934,DCAF13,E3 ligase ,DCAF,0,variable,no ENSG00000134574,DDB2,E3 ligase ,DCAF,5,variable,yes ENSG00000143476,DTL,E3 ligase ,DCAF,15,variable,no ENSG00000074266,EED,E3 ligase ,DCAF,0,variable,yes ENSG00000049167,ERCC8,E3 ligase ,DCAF,0,variable,yes ENSG00000172354,GNB2,E3 ligase ,DCAF,2,variable,no ENSG00000105447,GRWD1,E3 ligase ,DCAF,0,variable,no ENSG00000140854,KATNB1,E3 ligase ,DCAF,2,variable,yes ENSG00000073536,NLE1,E3 ligase ,DCAF,0,variable,no ENSG00000139323,POC1B,E3 ligase ,DCAF,2,variable,yes ENSG00000136045,PWP1,E3 ligase ,DCAF,0,core,no ENSG00000162521,RBBP4,E3 ligase ,DCAF,0,core,no ENSG00000117222,RBBP5,E3 ligase ,DCAF,0,variable,no ENSG00000102054,RBBP7,E3 ligase ,DCAF,2,variable,no ENSG00000060688,SNRNP40,E3 ligase ,DCAF,0,variable,no ENSG00000196781,TLE1,E3 ligase ,DCAF,4,variable,no ENSG00000065717,TLE2,E3 ligase ,DCAF,11,variable,no ENSG00000140332,TLE3,E3 ligase ,DCAF,7,variable,no ENSG00000138442,WDR12,E3 ligase ,DCAF,3,variable,no ENSG00000196363,WDR5,E3 ligase ,DCAF,1,variable,no ENSG00000196981,WDR5B,E3 ligase ,DCAF,1,variable,no ENSG00000140395,WDR61,E3 ligase ,DCAF,0,core,no ENSG00000092470,WDR76,E3 ligase ,DCAF,6,variable,no ENSG00000164091,WDR82,E3 ligase ,DCAF,0,core,no ENSG00000113851,CRBN,E3 ligase ,DCAF,0,core,yes ENSG00000132017,DCAF15,E3 ligase ,DCAF,3,variable,no ENSG00000163257,DCAF16,E3 ligase ,DCAF,0,variable,no ENSG00000115827,DCAF17,E3 ligase ,DCAF,0,variable,yes ENSG00000130311,DDA1,E3 ligase ,DCAF,0,core,no ENSG00000140543,DET1,E3 ligase ,DCAF,3,variable,no ENSG00000169905,TOR1AIP2,E3 ligase ,DCAF,2,variable,no ENSG00000100991,TRPC4AP,E3 ligase ,DCAF,1,variable,no ENSG00000064726,BTBD1,E3 ligase ,BTB,1,variable,no ENSG00000222009,BTBD19,E3 ligase ,BTB,10,variable,no ENSG00000133243,BTBD2,E3 ligase ,BTB,2,variable,no ENSG00000132640,BTBD3,E3 ligase ,BTB,6,variable,no ENSG00000184887,BTBD6,E3 ligase ,BTB,2,variable,no ENSG00000011114,BTBD7,E3 ligase ,BTB,1,variable,no ENSG00000183826,BTBD9,E3 ligase ,BTB,3,variable,no ENSG00000087338,GMCL1,E3 ligase ,BTB,0,variable,no ENSG00000108679,LGALS3BP,E3 ligase ,BTB,9,variable,no ENSG00000185972,CCIN,E3 ligase ,BTB,15,variable,no ENSG00000171617,ENC1,E3 ligase ,BTB,13,variable,no ENSG00000261609,GAN,E3 ligase ,BTB,5,variable,yes ENSG00000197429,IPP,E3 ligase ,BTB,1,variable,no ENSG00000116679,IVNS1ABP,E3 ligase ,BTB,2,variable,yes ENSG00000187715,KBTBD12,E3 ligase ,BTB,18,variable,no ENSG00000170852,KBTBD2,E3 ligase ,BTB,1,variable,no ENSG00000182359,KBTBD3,E3 ligase ,BTB,1,variable,no ENSG00000123444,KBTBD4,E3 ligase ,BTB,1,variable,no ENSG00000165572,KBTBD6,E3 ligase ,BTB,7,variable,no ENSG00000120696,KBTBD7,E3 ligase ,BTB,3,variable,no ENSG00000163376,KBTBD8,E3 ligase ,BTB,15,variable,no ENSG00000079999,KEAP1,E3 ligase ,BTB,1,variable,no ENSG00000150361,KLHL1,E3 ligase ,BTB,28,variable,no ENSG00000161594,KLHL10,E3 ligase ,BTB,5,variable,yes ENSG00000178502,KLHL11,E3 ligase ,BTB,4,variable,no ENSG00000117153,KLHL12,E3 ligase ,BTB,0,core,no ENSG00000003096,KLHL13,E3 ligase ,BTB,8,variable,no ENSG00000197705,KLHL14,E3 ligase ,BTB,15,variable,no ENSG00000174010,KLHL15,E3 ligase ,BTB,2,variable,yes ENSG00000187961,KLHL17,E3 ligase ,BTB,3,variable,no ENSG00000114648,KLHL18,E3 ligase ,BTB,0,variable,no ENSG00000109466,KLHL2,E3 ligase ,BTB,7,variable,no ENSG00000076321,KLHL20,E3 ligase ,BTB,0,variable,no ENSG00000162413,KLHL21,E3 ligase ,BTB,2,variable,no ENSG00000099910,KLHL22,E3 ligase ,BTB,1,variable,no ENSG00000213160,KLHL23,E3 ligase ,BTB,6,variable,no ENSG00000114796,KLHL24,E3 ligase ,BTB,3,variable,yes ENSG00000183655,KLHL25,E3 ligase ,BTB,3,variable,no ENSG00000167487,KLHL26,E3 ligase ,BTB,1,variable,no ENSG00000179454,KLHL28,E3 ligase ,BTB,0,variable,no ENSG00000119771,KLHL29,E3 ligase ,BTB,9,variable,no ENSG00000146021,KLHL3,E3 ligase ,BTB,7,variable,yes ENSG00000168427,KLHL30,E3 ligase ,BTB,18,variable,no ENSG00000124743,KLHL31,E3 ligase ,BTB,16,variable,no ENSG00000186231,KLHL32,E3 ligase ,BTB,19,variable,no ENSG00000185271,KLHL33,E3 ligase ,BTB,11,variable,no ENSG00000185915,KLHL34,E3 ligase ,BTB,22,variable,no ENSG00000149243,KLHL35,E3 ligase ,BTB,15,variable,no ENSG00000135686,KLHL36,E3 ligase ,BTB,1,variable,no ENSG00000175946,KLHL38,E3 ligase ,BTB,17,variable,no ENSG00000102271,KLHL4,E3 ligase ,BTB,22,variable,no ENSG00000157119,KLHL40,E3 ligase ,BTB,13,variable,yes ENSG00000239474,KLHL41,E3 ligase ,BTB,11,variable,yes ENSG00000087448,KLHL42,E3 ligase ,BTB,4,variable,no ENSG00000109790,KLHL5,E3 ligase ,BTB,5,variable,no ENSG00000172578,KLHL6,E3 ligase ,BTB,9,variable,no ENSG00000122550,KLHL7,E3 ligase ,BTB,4,variable,yes ENSG00000145332,KLHL8,E3 ligase ,BTB,1,variable,no ENSG00000198642,KLHL9,E3 ligase ,BTB,1,variable,no ENSG00000176595,KBTBD11,E3 ligase ,BTB,15,variable,no ENSG00000234438,KBTBD13,E3 ligase ,BTB,18,variable,yes ENSG00000099949,LZTR1,E3 ligase ,BTB,0,core,yes ENSG00000136636,KCTD3,E3 ligase ,BTB,4,variable,no ENSG00000160410,SHKBP1,E3 ligase ,BTB,4,variable,no ENSG00000180901,KCTD2,E3 ligase ,BTB,3,variable,no ENSG00000167977,KCTD5,E3 ligase ,BTB,1,variable,no ENSG00000168301,KCTD6,E3 ligase ,BTB,3,variable,no ENSG00000104756,KCTD9,E3 ligase ,BTB,7,variable,no ENSG00000110906,KCTD10,E3 ligase ,BTB,6,variable,no ENSG00000213859,KCTD11,E3 ligase ,BTB,5,variable,no ENSG00000174943,KCTD13,E3 ligase ,BTB,4,variable,no ENSG00000100379,KCTD17,E3 ligase ,BTB,7,variable,yes ENSG00000112078,KCTD20,E3 ligase ,BTB,1,variable,no ENSG00000188997,KCTD21,E3 ligase ,BTB,4,variable,no ENSG00000109079,TNFAIP1,E3 ligase ,BTB,2,variable,no ENSG00000121067,SPOP,E3 ligase ,BTB,3,variable,yes ENSG00000144228,SPOPL,E3 ligase ,BTB,3,variable,no ENSG00000114626,ABTB1,E3 ligase ,BTB,4,variable,no ENSG00000166016,ABTB2,E3 ligase ,BTB,9,variable,no ENSG00000185722,ANKFY1,E3 ligase ,BTB,1,variable,no ENSG00000151136,BTBD11,E3 ligase ,BTB,22,variable,no ENSG00000005700,IBTK,E3 ligase ,BTB,4,variable,no ENSG00000136144,RCBTB1,E3 ligase ,BTB,5,variable,yes ENSG00000136161,RCBTB2,E3 ligase ,BTB,2,variable,no ENSG00000140691,ARMC5,E3 ligase ,BTB,1,variable,yes ENSG00000072422,RHOBTB1,E3 ligase ,BTB,7,variable,no ENSG00000164292,RHOBTB3,E3 ligase ,BTB,9,variable,no ENSG00000008853,RHOBTB2,E3 ligase ,BTB,7,variable,yes ENSG00000148925,BTBD10,E3 ligase ,BTB,4,variable,no ENSG00000244234,GMCL1P1,E3 ligase ,BTB,2,variable,no ENSG00000197776,KLHDC1,E3 ligase ,substrate adaptors,2,variable,no ENSG00000165516,KLHDC2,E3 ligase ,substrate adaptors,1,variable,no ENSG00000124702,KLHDC3,E3 ligase ,substrate adaptors,3,variable,no ENSG00000128607,KLHDC10,E3 ligase ,substrate adaptors,2,variable,no ENSG00000141965,FEM1A,E3 ligase ,substrate adaptors,7,variable,no ENSG00000145780,FEM1C,E3 ligase ,substrate adaptors,2,variable,no ENSG00000062725,APPBP2,E3 ligase ,substrate adaptors,1,variable,no ENSG00000165501,LRR1,E3 ligase ,substrate adaptors,3,variable,no ENSG00000185686,PRAME,E3 ligase ,substrate adaptors,10,variable,no ENSG00000160445,ZER1,E3 ligase ,substrate adaptors,2,variable,no ENSG00000203995,ZYG11A,E3 ligase ,substrate adaptors,20,variable,no ENSG00000162378,ZYG11B,E3 ligase ,substrate adaptors,2,variable,no ENSG00000214655,ZSWIM8,E3 ligase ,substrate adaptors,1,variable,no ENSG00000169018,FEM1B,E3 ligase ,substrate adaptors,1,variable,no ENSG00000001629,ANKIB1,E3 ligase ,"Ariadne, ankyrin repeats, UIM",0,variable,no ENSG00000166233,ARIH1,E3 ligase ,Ariadne,1,variable,no ENSG00000177479,ARIH2,E3 ligase ,Ariadne,1,variable,no ENSG00000013561,RNF14,E3 ligase ,RWD,1,variable,no ENSG00000034677,RNF19A,E3 ligase ,assorted,0,core,no ENSG00000116514,RNF19B,E3 ligase ,assorted,3,variable,no ENSG00000151692,RNF144A,E3 ligase ,assorted,10,variable,no ENSG00000137393,RNF144B,E3 ligase ,assorted,12,variable,no ENSG00000011275,RNF216,E3 ligase ,assorted,1,variable,yes ENSG00000146373,RNF217,E3 ligase ,assorted,4,variable,no ENSG00000101871,MID1,E3 ligase ,TRIM,8,variable,yes ENSG00000080561,MID2,E3 ligase ,TRIM,4,variable,yes ENSG00000152503,TRIM36,E3 ligase ,TRIM,23,variable,yes ENSG00000100505,TRIM9,E3 ligase ,TRIM,24,variable,no ENSG00000119283,TRIM67,E3 ligase ,TRIM,26,variable,no ENSG00000163462,TRIM46,E3 ligase ,TRIM,22,variable,no ENSG00000138100,TRIM54,E3 ligase ,TRIM,20,variable,no ENSG00000147573,TRIM55,E3 ligase ,TRIM,24,variable,no ENSG00000158022,TRIM63,E3 ligase ,TRIM,15,variable,no ENSG00000155890,TRIM42,E3 ligase ,TRIM,1,variable,no ENSG00000132109,TRIM21,E3 ligase ,TRIM,4,variable,no ENSG00000121236,TRIM6,E3 ligase ,TRIM,14,variable,no ENSG00000162931,TRIM17,E3 ligase ,TRIM,15,variable,no ENSG00000146755,TRIM50,E3 ligase ,TRIM,11,variable,no ENSG00000132256,TRIM5,E3 ligase ,TRIM,8,variable,no ENSG00000132274,TRIM22,E3 ligase ,TRIM,8,variable,no ENSG00000132481,TRIM47,E3 ligase ,TRIM,7,variable,no ENSG00000146054,TRIM7,E3 ligase ,TRIM,16,variable,no ENSG00000204713,TRIM27,E3 ligase ,TRIM,2,variable,no ENSG00000154370,TRIM11,E3 ligase ,TRIM,3,variable,no ENSG00000234127,TRIM26,E3 ligase ,TRIM,1,variable,no ENSG00000104228,TRIM35,E3 ligase ,TRIM,1,variable,no ENSG00000112343,TRIM38,E3 ligase ,TRIM,8,variable,no ENSG00000204599,TRIM39,E3 ligase ,TRIM,1,variable,no ENSG00000146063,TRIM41,E3 ligase ,TRIM,1,variable,no ENSG00000162722,TRIM58,E3 ligase ,TRIM,17,variable,no ENSG00000116525,TRIM62,E3 ligase ,TRIM,5,variable,no ENSG00000177238,TRIM72,E3 ligase ,TRIM,10,variable,no ENSG00000146833,TRIM4,E3 ligase ,TRIM,0,variable,no ENSG00000258659,TRIM34,E3 ligase ,TRIM,6,variable,no ENSG00000141569,TRIM65,E3 ligase ,TRIM,1,variable,no ENSG00000185880,TRIM69,E3 ligase ,TRIM,2,variable,no ENSG00000121060,TRIM25,E3 ligase ,TRIM,3,variable,no ENSG00000184108,TRIML1,E3 ligase ,TRIM,2,variable,no ENSG00000167333,TRIM68,E3 ligase ,TRIM,0,variable,no ENSG00000122779,TRIM24,E3 ligase ,TRIM,4,variable,no ENSG00000130726,TRIM28,E3 ligase ,TRIM,1,variable,no ENSG00000197323,TRIM33,E3 ligase ,TRIM,0,variable,no ENSG00000134253,TRIM45,E3 ligase ,TRIM,7,variable,no ENSG00000109654,TRIM2,E3 ligase ,TRIM,9,variable,yes ENSG00000110171,TRIM3,E3 ligase ,TRIM,2,variable,no ENSG00000206557,TRIM71,E3 ligase ,TRIM,25,variable,yes ENSG00000119401,TRIM32,E3 ligase ,TRIM,3,variable,yes ENSG00000169871,TRIM56,E3 ligase ,TRIM,4,variable,no ENSG00000108395,TRIM37,E3 ligase ,TRIM,5,variable,yes ENSG00000113595,TRIM23,E3 ligase ,TRIM,3,variable,no ENSG00000204977,TRIM13,E3 ligase ,TRIM,1,variable,no ENSG00000213186,TRIM59,E3 ligase ,TRIM,13,variable,no ENSG00000140464,PML,E3 ligase ,TRIM,7,variable,yes ENSG00000158286,RNF207,E3 ligase ,TRIM,11,variable,no ENSG00000204616,TRIM31,E3 ligase ,TRIM,14,variable,no ENSG00000171206,TRIM8,E3 ligase ,TRIM,1,variable,no ENSG00000178809,TRIM73,E3 ligase ,TRIM,4,variable,no ENSG00000155428,TRIM74,E3 ligase ,TRIM,4,variable,no ENSG00000168159,RNF187,E3 ligase ,TRIM,2,variable,no ENSG00000183439,TRIM61,E3 ligase ,TRIM,13,variable,no ENSG00000183718,TRIM52,E3 ligase ,TRIM,0,core,no ENSG00000103313,MEFV,E3 ligase ,TRIM,12,variable,yes ENSG00000164309,CMYA5,E3 ligase ,TRIM,13,variable,no ENSG00000106785,TRIM14,E3 ligase ,TRIM,10,variable,no ENSG00000221926,TRIM16,E3 ligase ,TRIM,5,variable,no ENSG00000108448,TRIM16L,E3 ligase ,TRIM,6,variable,no ENSG00000179046,TRIML2,E3 ligase ,TRIM,12,variable,no ENSG00000166436,TRIM66,E3 ligase ,TRIM,2,variable,no ENSG00000137699,TRIM29,E3 ligase ,TRIM,26,variable,no ENSG00000166326,TRIM44,E3 ligase ,TRIM,2,variable,yes ENSG00000128253,RFPL2,E3 ligase ,SPRY but not TRIM,25,variable,no ENSG00000204618,RNF39,E3 ligase ,SPRY but not TRIM,16,variable,no ENSG00000164068,RNF123,E3 ligase ,SPRY but not TRIM,3,variable,no ENSG00000181481,RNF135,E3 ligase ,SPRY but not TRIM,6,variable,no ENSG00000159579,RSPRY1,E3 ligase ,SPRY but not TRIM,0,variable,yes ENSG00000110330,BIRC2,E3 ligase ,BIRC / IAP,0,core,no ENSG00000023445,BIRC3,E3 ligase ,BIRC / IAP,7,variable,no ENSG00000101197,BIRC7,E3 ligase ,BIRC / IAP,16,variable,no ENSG00000163098,BIRC8,E3 ligase ,BIRC / IAP,1,variable,no ENSG00000101966,XIAP,E3 ligase ,BIRC / IAP,1,variable,yes ENSG00000012048,BRCA1,E3 ligase ,BRCA1,4,variable,yes ENSG00000138376,BARD1,E3 ligase ,BRCA1-associated,9,variable,yes ENSG00000089234,BRAP,E3 ligase ,BRCA1-associated,1,variable,no ENSG00000110395,CBL,E3 ligase ,"CBL, UBA",5,variable,yes ENSG00000114423,CBLB,E3 ligase ,"CBL, UBA",5,variable,no ENSG00000142273,CBLC,E3 ligase ,CBL,28,variable,no ENSG00000118518,RNF146,E3 ligase ,Deltex,3,variable,no ENSG00000135144,DTX1,E3 ligase ,Deltex,12,variable,no ENSG00000091073,DTX2,E3 ligase ,Deltex,8,variable,no ENSG00000110042,DTX4,E3 ligase ,Deltex,14,variable,no ENSG00000178498,DTX3,E3 ligase ,Deltex,7,variable,no ENSG00000163840,DTX3L,E3 ligase ,Deltex,6,variable,no ENSG00000082996,RNF13,E3 ligase ,Goliath,3,variable,yes ENSG00000133135,RNF128,E3 ligase ,Goliath,26,variable,no ENSG00000113269,RNF130,E3 ligase ,Goliath,5,variable,no ENSG00000188050,RNF133,E3 ligase ,Goliath,14,variable,no ENSG00000235631,RNF148,E3 ligase ,Goliath,11,variable,no ENSG00000163162,RNF149,E3 ligase ,Goliath,2,variable,no ENSG00000170153,RNF150,E3 ligase ,Goliath,12,variable,no ENSG00000108523,RNF167,E3 ligase ,Goliath,1,variable,no ENSG00000105428,ZNRF4,E3 ligase ,Goliath,5,variable,no ENSG00000105879,CBLL1,E3 ligase ,Hakai,1,variable,no ENSG00000175809,ZNF645,E3 ligase ,Hakai,1,variable,no ENSG00000170604,IRF2BP1,E3 ligase ,IRF2 binding,0,core,no ENSG00000168264,IRF2BP2,E3 ligase ,IRF2 binding,1,variable,yes ENSG00000119669,IRF2BPL,E3 ligase ,IRF2 binding,0,core,yes ENSG00000154359,LONRF1,E3 ligase ,LON,2,variable,no ENSG00000170500,LONRF2,E3 ligase ,LON,15,variable,no ENSG00000175556,LONRF3,E3 ligase ,LON,13,variable,no ENSG00000133606,MKRN1,E3 ligase ,Makorin,2,variable,no ENSG00000179455,MKRN3,E3 ligase ,Makorin,23,variable,yes ENSG00000075975,MKRN2,E3 ligase ,Makorin,2,variable,no ENSG00000145416,1-Mar,E3 ligase ,MARCH,3,variable,no ENSG00000099785,2-Mar,E3 ligase ,MARCH,5,variable,no ENSG00000173926,3-Mar,E3 ligase ,MARCH,14,variable,no ENSG00000144583,4-Mar,E3 ligase ,MARCH,25,variable,no ENSG00000198060,5-Mar,E3 ligase ,MARCH,0,core,no ENSG00000145495,6-Mar,E3 ligase ,MARCH,0,core,yes ENSG00000136536,7-Mar,E3 ligase ,MARCH,0,core,no ENSG00000165406,8-Mar,E3 ligase ,MARCH,2,variable,no ENSG00000139266,9-Mar,E3 ligase ,MARCH,1,variable,no ENSG00000173838,10-Mar,E3 ligase ,MARCH,19,variable,no ENSG00000183654,11-Mar,E3 ligase ,MARCH,26,variable,no ENSG00000135679,MDM2,E3 ligase ,Mdm,2,variable,yes ENSG00000198625,MDM4,E3 ligase ,Mdm,1,variable,yes ENSG00000254726,MEX3A,E3 ligase ,MEX3,10,variable,no ENSG00000183496,MEX3B,E3 ligase ,MEX3,7,variable,no ENSG00000176624,MEX3C,E3 ligase ,MEX3,1,variable,no ENSG00000181588,MEX3D,E3 ligase ,MEX3,3,variable,no ENSG00000101752,MIB1,E3 ligase ,Mindbomb,1,variable,yes ENSG00000197530,MIB2,E3 ligase ,Mindbomb,1,variable,no ENSG00000086102,NFX1,E3 ligase ,NFX,0,core,no ENSG00000170448,NFXL1,E3 ligase ,NFX,1,variable,no ENSG00000107954,NEURL1,E3 ligase ,Neuralized,29,variable,no ENSG00000214357,NEURL1B,E3 ligase ,Neuralized,13,variable,no ENSG00000163121,NEURL3,E3 ligase ,Neuralized,18,variable,no ENSG00000072201,LNX1,E3 ligase ,PDZ,10,variable,no ENSG00000139517,LNX2,E3 ligase ,PDZ,1,variable,no ENSG00000165966,PDZRN4,E3 ligase ,PDZ,12,variable,no ENSG00000121440,PDZRN3,E3 ligase ,PDZ,14,variable,no ENSG00000197329,PELI1,E3 ligase ,Pellino,6,variable,no ENSG00000139946,PELI2,E3 ligase ,Pellino,6,variable,no ENSG00000174516,PELI3,E3 ligase ,Pellino,5,variable,no ENSG00000164751,PEX2,E3 ligase ,PEX,1,variable,yes ENSG00000157911,PEX10,E3 ligase ,PEX,1,variable,yes ENSG00000108733,PEX12,E3 ligase ,PEX,2,variable,yes ENSG00000181191,PJA1,E3 ligase ,Praja,2,variable,no ENSG00000198961,PJA2,E3 ligase ,Praja,1,variable,no ENSG00000155827,RNF20,E3 ligase ,RNF20/40 ish,0,variable,no ENSG00000103549,RNF40,E3 ligase ,RNF20/40 ish,1,variable,no ENSG00000135870,RC3H1,E3 ligase ,Roquin,0,variable,yes ENSG00000056586,RC3H2,E3 ligase ,Roquin,0,variable,no ENSG00000070950,RAD18,E3 ligase ,SAP,0,variable,no ENSG00000092871,RFFL,E3 ligase ,SAP,5,variable,no ENSG00000170633,RNF34,E3 ligase ,SAP,1,variable,no ENSG00000154447,SH3RF1,E3 ligase ,SH3,4,variable,no ENSG00000156463,SH3RF2,E3 ligase ,SH3,23,variable,no ENSG00000172985,SH3RF3,E3 ligase ,SH3,8,variable,no ENSG00000196470,SIAH1,E3 ligase ,"SIAH-type ZnF, SIA TRAF-like domain",0,variable,no ENSG00000181788,SIAH2,E3 ligase ,"SIAH-type ZnF, SIA TRAF-like domain",6,variable,no ENSG00000215475,SIAH3,E3 ligase ,SIA TRAF-like domain,26,variable,no ENSG00000179580,RNF151,E3 ligase ,SIAH-type ZnF,3,variable,no ENSG00000181852,RNF41,E3 ligase ,SIAH-type ZnF,0,variable,no ENSG00000127191,TRAF2,E3 ligase ,"TRAF-type ZnF, MATH/TRAF ",0,variable,no ENSG00000131323,TRAF3,E3 ligase ,"TRAF-type ZnF, MATH/TRAF ",2,variable,yes ENSG00000076604,TRAF4,E3 ligase ,"TRAF-type ZnF, MATH/TRAF ",10,variable,no ENSG00000082512,TRAF5,E3 ligase ,"TRAF-type ZnF, MATH/TRAF ",9,variable,no ENSG00000175104,TRAF6,E3 ligase ,"TRAF-type ZnF, MATH/TRAF ",0,variable,no ENSG00000131653,TRAF7,E3 ligase ,TRAF-type ZnF,1,variable,yes ENSG00000124226,RNF114,E3 ligase ,TRAC-1,1,variable,no ENSG00000101695,RNF125,E3 ligase ,TRAC-1,10,variable,yes ENSG00000134758,RNF138,E3 ligase ,TRAC-1,2,variable,no ENSG00000158717,RNF166,E3 ligase ,TRAC-1,2,variable,no ENSG00000176407,KCMF1,E3 ligase ,TRAC-1,1,variable,no ENSG00000110107,PRPF19,E3 ligase ,UBOX,1,variable,no ENSG00000196151,WDSUB1,E3 ligase ,UBOX,0,variable,no ENSG00000100023,PPIL2,E3 ligase ,UBOX,0,core,no ENSG00000103266,STUB1,E3 ligase ,UBOX,2,variable,yes ENSG00000110344,UBE4A,E3 ligase ,UBOX,0,variable,no ENSG00000122257,RBBP6,E3 ligase ,UBOX,0,core,no ENSG00000185019,UBOX5,E3 ligase ,UBOX,0,variable,no ENSG00000142546,NOSIP,E3 ligase ,UBOX,3,variable,no ENSG00000144357,UBR3,E3 ligase ,UBR,2,variable,no ENSG00000127481,UBR4,E3 ligase ,UBR,0,core,no ENSG00000012963,UBR7,E3 ligase ,UBR,1,variable,no ENSG00000132478,UNK,E3 ligase ,Unkempt,0,variable,no ENSG00000059145,UNKL,E3 ligase ,Unkempt,1,variable,no ENSG00000156931,VPS8,E3 ligase ,VPS-associated,0,variable,no ENSG00000160695,VPS11,E3 ligase ,VPS-associated,0,core,yes ENSG00000006715,VPS41,E3 ligase ,VPS-associated,2,variable,no ENSG00000186187,ZNRF1,E3 ligase ,ZNRF,3,variable,no ENSG00000180233,ZNRF2,E3 ligase ,ZNRF,2,variable,no ENSG00000198862,LTN1,E3 ligase ,other,0,variable,no ENSG00000095015,MAP3K1,E3 ligase ,other,6,variable,yes ENSG00000163012,ZSWIM2,E3 ligase ,other,9,variable,no ENSG00000070047,PHRF1,E3 ligase ,other,0,core,no ENSG00000146414,SHPRH,E3 ligase ,other,1,variable,no ENSG00000071794,HLTF,E3 ligase ,other,4,variable,no ENSG00000128482,RNF112,E3 ligase ,other,14,variable,no ENSG00000173821,RNF213,E3 ligase ,other,4,variable,yes ENSG00000105982,RNF32,E3 ligase ,other,4,variable,no ENSG00000148356,LRSAM1,E3 ligase ,other,1,variable,yes ENSG00000187566,NHLRC1,E3 ligase ,other,6,variable,yes ENSG00000080802,CNOT4,E3 ligase ,other,1,variable,no ENSG00000163481,RNF25,E3 ligase ,other,0,core,no ENSG00000182670,TTC3,E3 ligase ,other,5,variable,no ENSG00000165917,RAPSN,E3 ligase ,other,13,variable,yes ENSG00000007944,MYLIP,E3 ligase ,other,8,variable,no ENSG00000020426,MNAT1,E3 ligase ,other,2,variable,no ENSG00000168411,RFWD3,E3 ligase ,other,3,variable,yes ENSG00000115392,FANCL,E3 ligase ,other,4,variable,no ENSG00000103429,BFAR,E3 ligase ,other,1,variable,no ENSG00000100814,CCNB1IP1,E3 ligase ,other,1,variable,no ENSG00000100532,CGRRF1,E3 ligase ,other,2,variable,no ENSG00000072609,CHFR,E3 ligase ,other,1,variable,no ENSG00000163357,DCST1,E3 ligase ,other,10,variable,no ENSG00000198919,DZIP3,E3 ligase ,other,6,variable,no ENSG00000102858,MGRN1,E3 ligase ,other,2,variable,no ENSG00000174579,MSL2,E3 ligase ,other,1,variable,no ENSG00000090432,MUL1,E3 ligase ,other,1,variable,no ENSG00000005810,MYCBP2,E3 ligase ,other,0,variable,no ENSG00000169189,NSMCE1,E3 ligase ,other,0,core,no ENSG00000152193,RNF219,E3 ligase ,other,2,variable,no ENSG00000163743,RCHY1,E3 ligase ,other,1,variable,no ENSG00000131263,RLIM,E3 ligase ,other,1,variable,yes ENSG00000063978,RNF4,E3 ligase ,other,0,core,no ENSG00000204308,RNF5,E3 ligase ,other,1,variable,no ENSG00000127870,RNF6,E3 ligase ,other,1,variable,yes ENSG00000112130,RNF8,E3 ligase ,other,0,variable,no ENSG00000022840,RNF10,E3 ligase ,other,2,variable,no ENSG00000123091,RNF11,E3 ligase ,other,2,variable,no ENSG00000132972,RNF17,E3 ligase ,other,8,variable,no ENSG00000101236,RNF24,E3 ligase ,other,5,variable,no ENSG00000173456,RNF26,E3 ligase ,other,0,core,no ENSG00000137075,RNF38,E3 ligase ,other,2,variable,no ENSG00000108375,RNF43,E3 ligase ,other,23,variable,yes ENSG00000146083,RNF44,E3 ligase ,other,1,variable,no ENSG00000157450,RNF111,E3 ligase ,other,0,variable,no ENSG00000239305,RNF103,E3 ligase ,other,3,variable,no ENSG00000125352,RNF113A,E3 ligase ,other,2,variable,yes ENSG00000139797,RNF113B,E3 ligase ,other,8,variable,no ENSG00000265491,RNF115,E3 ligase ,other,4,variable,no ENSG00000137522,RNF121,E3 ligase ,other,0,variable,no ENSG00000133874,RNF122,E3 ligase ,other,12,variable,no ENSG00000070423,RNF126,E3 ligase ,other,1,variable,no ENSG00000170881,RNF139,E3 ligase ,other,1,variable,yes ENSG00000110315,RNF141,E3 ligase ,other,6,variable,no ENSG00000145860,RNF145,E3 ligase ,other,3,variable,no ENSG00000176641,RNF152,E3 ligase ,other,12,variable,no ENSG00000141576,RNF157,E3 ligase ,other,21,variable,no ENSG00000141622,RNF165,E3 ligase ,other,14,variable,no ENSG00000163961,RNF168,E3 ligase ,other,1,variable,yes ENSG00000166439,RNF169,E3 ligase ,other,2,variable,no ENSG00000120925,RNF170,E3 ligase ,other,2,variable,yes ENSG00000145428,RNF175,E3 ligase ,other,19,variable,no ENSG00000164197,RNF180,E3 ligase ,other,2,variable,no ENSG00000168894,RNF181,E3 ligase ,other,1,variable,no ENSG00000180537,RNF182,E3 ligase ,other,19,variable,no ENSG00000165188,RNF183,E3 ligase ,other,11,variable,no ENSG00000138942,RNF185,E3 ligase ,other,1,variable,no ENSG00000212864,RNF208,E3 ligase ,other,10,variable,no ENSG00000178222,RNF212,E3 ligase ,other,13,variable,yes ENSG00000215277,RNF212B,E3 ligase ,other,3,variable,no ENSG00000167257,RNF214,E3 ligase ,other,1,variable,no ENSG00000099999,RNF215,E3 ligase ,other,1,variable,no ENSG00000187147,RNF220,E3 ligase ,other,2,variable,no ENSG00000189051,RNF222,E3 ligase ,other,15,variable,no ENSG00000237330,RNF223,E3 ligase ,other,15,variable,no ENSG00000233198,RNF224,E3 ligase ,other,13,variable,no ENSG00000269855,RNF225,E3 ligase ,other,13,variable,no ENSG00000179859,AC025335.1,E3 ligase ,other,8,variable,no ENSG00000189050,RNFT1,E3 ligase ,other,2,variable,no ENSG00000135119,RNFT2,E3 ligase ,other,16,variable,no ENSG00000197579,TOPORS,E3 ligase ,other,0,variable,yes ENSG00000183763,TRAIP,E3 ligase ,other,4,variable,yes ENSG00000167962,ZNF598,E3 ligase ,other,1,variable,no ENSG00000183579,ZNRF3,E3 ligase ,other,3,variable,no ENSG00000158019,BRE,E3 ligase ,BRCA1-specific,2,variable,no ENSG00000056558,TRAF1,E3 ligase ,TRAF2-specific,4,variable,no ENSG00000198681,MAGEA1,E3 ligase ,MAGE,1,variable,no ENSG00000221867,MAGEA3,E3 ligase ,MAGE,1,variable,no ENSG00000197172,MAGEA6,E3 ligase ,MAGE,2,variable,no ENSG00000147381,MAGEA4,E3 ligase ,MAGE,1,variable,no ENSG00000046774,MAGEC2,E3 ligase ,MAGE,1,variable,no ENSG00000179222,MAGED1,E3 ligase ,MAGE,4,variable,no ENSG00000177383,MAGEF1,E3 ligase ,MAGE,3,variable,no ENSG00000185115,NSMCE3,E3 ligase ,MAGE,1,variable,yes ENSG00000254585,MAGEL2,E3 ligase ,MAGE,18,variable,yes ENSG00000185247,MAGEA11,E3 ligase ,MAGE,4,variable,no ENSG00000118503,TNFAIP3,E3 ligase ,with OTU,9,variable,yes ENSG00000215041,NEURL4,E3 ligase ,NHR,0,core,no ENSG00000043143,JADE2,E3 ligase ,PHD-type ZnF,4,variable,no ENSG00000167967,E4F1,E3 ligase ,nan,0,core,no ENSG00000168936,TMEM129,E3 ligase ,nan,0,core,no ENSG00000186660,ZFP91,E3 ligase ,nan,2,variable,no ENSG00000154493,C10orf90,E3 ligase ,nan,26,variable,no ENSG00000122877,EGR2,E3 ligase ,nan,10,variable,yes ENSG00000204619,PPP1R11,E3 ligase ,nan,1,variable,no ENSG00000056972,TRAF3IP2,E3 ligase ,nan,7,variable,yes ENSG00000033800,PIAS1,E3 ligase ,sumoylation,1,variable,no ENSG00000078043,PIAS2,E3 ligase ,sumoylation,4,variable,no ENSG00000131788,PIAS3,E3 ligase ,sumoylation,2,variable,no ENSG00000105229,PIAS4,E3 ligase ,sumoylation,2,variable,no ENSG00000156831,NSMCE2,E3 ligase ,sumoylation,1,variable,yes ENSG00000153201,RANBP2,E3 ligase ,sumoylation,0,core,yes ENSG00000141582,CBX4,E3 ligase ,sumoylation,3,variable,no ENSG00000214717,ZBED1,E3 ligase ,sumoylation,4,variable,no ENSG00000112200,ZNF451,E3 ligase ,sumoylation,0,variable,no ENSG00000043093,DCUN1D1,E3 ligase ,NEDDylation,1,variable,no ENSG00000150401,DCUN1D2,E3 ligase ,NEDDylation,5,variable,no ENSG00000188215,DCUN1D3,E3 ligase ,NEDDylation,2,variable,no ENSG00000109184,DCUN1D4,E3 ligase ,NEDDylation,2,variable,no ENSG00000137692,DCUN1D5,E3 ligase ,NEDDylation,1,variable,no ENSG00000014123,UFL1,E3 ligase ,UFMylation,2,variable,no ENSG00000108465,CDK5RAP3,E3 ligase ,UFMylation,0,core,no ENSG00000198171,DDRGK1,E3 ligase ,UFMylation adaptor,0,core,yes ENSG00000081087,OSTM1,E3 ligase ,none,3,variable,yes ENSG00000091732,ZC3HC1,E3 ligase ,none,1,variable,no ENSG00000101849,TBL1X,E3 ligase ,none,6,variable,yes ENSG00000111665,CDCA3,E3 ligase ,none,6,variable,no ENSG00000116161,CACYBP,E3 ligase ,none,2,variable,no ENSG00000184990,SIVA1,E3 ligase ,none,3,variable,no ENSG00000158552,ZFAND2B,p97 and associates,"VIM, AN1, UIM",2,variable,no ENSG00000151092,NGLY1,p97 and associates,deglycolsylase,3,variable,yes ENSG00000165280,VCP,p97 and associates,nan,1,variable,yes ENSG00000182446,NPLOC4,p97 and associates,MPN,1,variable,no ENSG00000175073,VCPIP1,p97 and associates,OTU,0,variable,no ENSG00000167770,OTUB1,p97 and associates,OTU,0,core,no ENSG00000169918,OTUD7A,p97 and associates,OTU ,14,variable,no ENSG00000264522,OTUD7B,p97 and associates,OTU ,4,variable,no ENSG00000066427,ATXN3,p97 and associates,Josephin,0,variable,yes ENSG00000162298,SYVN1,p97 and associates,RING,2,variable,no ENSG00000130939,UBE4B,p97 and associates,RING,2,variable,no ENSG00000159461,AMFR,p97 and associates,UBOX,1,variable,no ENSG00000092098,RNF31,p97 and associates,RBR,1,variable,no ENSG00000010072,SPRTN,p97 and associates,metalloprotease,1,variable,yes ENSG00000144468,RHBDD1,p97 and associates,serine protease,1,variable,no ENSG00000137055,PLAA,p97 and associates,PLA activator,1,variable,yes ENSG00000136986,DERL1,p97 and associates,SHP,1,variable,no ENSG00000072849,DERL2,p97 and associates,SHP,2,variable,no ENSG00000070010,UFD1L,p97 and associates,"SHP, UT3",0,core,no ENSG00000169696,ASPSCR1,p97 and associates,"UBX, UBXL, SHP",1,variable,yes ENSG00000173960,UBXN2A,p97 and associates,"UBX, SHP, SEP",3,variable,no ENSG00000215114,UBXN2B,p97 and associates,"UBX, SHP, SEP",2,variable,no ENSG00000158062,UBXN11,p97 and associates,"UBX, SHP, SEP",7,variable,no ENSG00000088833,NSFL1C,p97 and associates,"UBX, SHP, SEP, UBA",1,variable,no ENSG00000144224,UBXN4,p97 and associates,"UBX, thioredoxin-like",0,core,no ENSG00000163960,UBXN7,p97 and associates,"UBX, thioredoxin-like, UBA",0,variable,no ENSG00000185104,FAF1,p97 and associates,"UBX, thioredoxin-like, UBA",2,variable,no ENSG00000113194,FAF2,p97 and associates,"UBX, thioredoxin-like, UBA",0,variable,no ENSG00000013374,NUB1,p97 and associates,"UBX, VBM, UBL, UBA",0,core,no ENSG00000167671,UBXN6,p97 and associates,"UBX, PUB, VIM",2,variable,no ENSG00000162191,UBXN1,p97 and associates,"UBX, UBA",1,variable,no ENSG00000104691,UBXN8,p97 and associates,UBX,5,variable,no ENSG00000162543,UBXN10,p97 and associates,UBX,15,variable,no ENSG00000131871,SELENOS,p97 and associates,VIM,3,variable,no ENSG00000198168,SVIP,p97 and associates,VIM,3,variable,no ENSG00000163516,ANKZF1,p97 and associates,"VIM, ankyrin repeats",3,variable,no ENSG00000129084,PSMA1,proteasome & associates,constitutive,1,variable,no ENSG00000106588,PSMA2,proteasome & associates,constitutive,1,variable,no ENSG00000100567,PSMA3,proteasome & associates,constitutive,2,variable,no ENSG00000041357,PSMA4,proteasome & associates,constitutive,1,variable,no ENSG00000143106,PSMA5,proteasome & associates,constitutive,0,core,no ENSG00000100902,PSMA6,proteasome & associates,constitutive,2,variable,yes ENSG00000101182,PSMA7,proteasome & associates,constitutive,2,variable,no ENSG00000008018,PSMB1,proteasome & associates,constitutive,1,variable,no ENSG00000126067,PSMB2,proteasome & associates,constitutive,0,core,no ENSG00000277791,PSMB3,proteasome & associates,constitutive,1,variable,no ENSG00000159377,PSMB4,proteasome & associates,constitutive,1,variable,yes ENSG00000100804,PSMB5,proteasome & associates,constitutive,2,variable,no ENSG00000142507,PSMB6,proteasome & associates,constitutive,1,variable,no ENSG00000136930,PSMB7,proteasome & associates,constitutive,0,core,no ENSG00000154611,PSMA8,proteasome & associates,specialized,10,variable,no ENSG00000204264,PSMB8,proteasome & associates,specialized,8,variable,yes ENSG00000240065,PSMB9,proteasome & associates,specialized,5,variable,yes ENSG00000205220,PSMB10,proteasome & associates,specialized,3,variable,no ENSG00000100764,PSMC1,proteasome & associates,ATPase,1,variable,no ENSG00000161057,PSMC2,proteasome & associates,ATPase,1,variable,no ENSG00000165916,PSMC3,proteasome & associates,ATPase,1,variable,no ENSG00000013275,PSMC4,proteasome & associates,ATPase,0,core,no ENSG00000087191,PSMC5,proteasome & associates,ATPase,0,core,no ENSG00000100519,PSMC6,proteasome & associates,ATPase,3,variable,no ENSG00000173692,PSMD1,proteasome & associates,nonATPase,2,variable,no ENSG00000175166,PSMD2,proteasome & associates,nonATPase,1,variable,no ENSG00000159352,PSMD4,proteasome & associates,nonATPase,1,variable,no ENSG00000130706,ADRM1,proteasome & associates,nonATPase,1,variable,no ENSG00000103035,PSMD7,proteasome & associates,nonATPase,1,variable,no ENSG00000115233,PSMD14,proteasome & associates,nonATPase,3,variable,no ENSG00000108344,PSMD3,proteasome & associates,nonATPase,1,variable,no ENSG00000163636,PSMD6,proteasome & associates,nonATPase,2,variable,no ENSG00000108671,PSMD11,proteasome & associates,nonATPase,1,variable,no ENSG00000099341,PSMD8,proteasome & associates,nonATPase,1,variable,no ENSG00000197170,PSMD12,proteasome & associates,nonATPase,1,variable,yes ENSG00000185627,PSMD13,proteasome & associates,nonATPase,1,variable,no ENSG00000127922,SEM1,proteasome & associates,nonATPase,1,variable,no ENSG00000132963,POMP,proteasome & associates,core particle,1,variable,yes ENSG00000183527,PSMG1,proteasome & associates,core particle,2,variable,no ENSG00000128789,PSMG2,proteasome & associates,core particle,0,core,no ENSG00000157778,PSMG3,proteasome & associates,core particle,1,variable,no ENSG00000180822,PSMG4,proteasome & associates,core particle,1,variable,no ENSG00000095261,PSMD5,proteasome & associates,regulatory particle,0,variable,no ENSG00000110801,PSMD9,proteasome & associates,regulatory particle,0,core,no ENSG00000101843,PSMD10,proteasome & associates,regulatory particle,1,variable,no ENSG00000175575,PAAF1,proteasome & associates,regulatory particle,4,variable,no ENSG00000136813,KIAA0368,proteasome & associates,inhibitor,1,variable,no ENSG00000068878,PSME4,proteasome & associates,activator,2,variable,no ENSG00000125818,PSMF1,proteasome & associates,activator,3,variable,no ENSG00000092010,PSME1,proteasome & associates,activator,4,variable,no ENSG00000100911,PSME2,proteasome & associates,activator,3,variable,no ENSG00000131467,PSME3,proteasome & associates,activator,0,core,no ENSG00000101557,USP14,proteasome & associates,USP,1,variable,no ENSG00000116750,UCHL5,proteasome & associates,UCH,2,variable,no ENSG00000114062,UBE3A,proteasome & associates,HECT,2,variable,yes ENSG00000009335,UBE3C,proteasome & associates,HECT,1,variable,no ENSG00000153827,TRIP12,proteasome & associates,HECT,2,variable,yes ENSG00000185345,PARK2,proteasome & associates,"RING, UBL",10,variable,no ENSG00000159459,UBR1,proteasome & associates,UBR,1,variable,yes ENSG00000024048,UBR2,proteasome & associates,UBR,3,variable,no ENSG00000170967,DDI1,proteasome & associates,aspartic peptidase,3,variable,no ENSG00000197312,DDI2,proteasome & associates,aspartic peptidase,4,variable,no ENSG00000204463,BAG6,proteasome & associates,chaperone,3,variable,no ENSG00000091164,TXNL1,proteasome & associates,thioredoxin-like,1,variable,no ENSG00000174574,AKIRIN1,proteasome & associates,Akirin,2,variable,no ENSG00000135334,AKIRIN2,proteasome & associates,Akirin,2,variable,no ENSG00000178381,ZFAND2A,proteasome & associates,AN1,3,variable,no ENSG00000158552,ZFAND2B,proteasome & associates,AN1,2,variable,no ENSG00000107372,ZFAND5,proteasome & associates,AN1,2,variable,no ENSG00000112208,BAG2,proteasome & associates,BAG,11,variable,no ENSG00000161011,SQSTM1,proteasome & associates,PB1,2,variable,yes ENSG00000175518,UBQLNL,proteasome & associates,UBL,11,variable,no ENSG00000167470,MIDN,proteasome & associates,UBL,6,variable,no ENSG00000179262,RAD23A,proteasome & associates,UBL,1,variable,no ENSG00000119318,RAD23B,proteasome & associates,UBL,1,variable,no ENSG00000135018,UBQLN1,proteasome & associates,UBL,0,core,no ENSG00000188021,UBQLN2,proteasome & associates,UBL,1,variable,yes ENSG00000175520,UBQLN3,proteasome & associates,UBL,4,variable,no ENSG00000160803,UBQLN4,proteasome & associates,UBL,2,variable,no ENSG00000082641,NFE2L1,proteasome & associates,transcription factor,5,variable,no ENSG00000116044,NFE2L2,proteasome & associates,transcription factor,2,variable,yes ENSG00000151092,NGLY1,proteasome & associates,deglycosylase,3,variable,yes ENSG00000115233,PSMD14,Ubiquitin and UBL,proteasome,3,variable,no ENSG00000101557,USP14,Ubiquitin and UBL,UBL (external),1,variable,no ENSG00000116750,UCHL5,Ubiquitin and UBL,nan,2,variable,no ENSG00000175073,VCPIP1,Ubiquitin and UBL,UBL,0,variable,no ENSG00000167770,OTUB1,Ubiquitin and UBL,assorted,0,core,no ENSG00000169918,OTUD7A,Ubiquitin and UBL,A20,14,variable,no ENSG00000264522,OTUD7B,Ubiquitin and UBL,A20,4,variable,no ENSG00000066427,ATXN3,Ubiquitin and UBL,UIM,0,variable,yes ENSG00000180667,YOD1,Ubiquitin and UBL,UBL,4,variable,no ENSG00000090686,USP48,Ubiquitin and UBL,"DUSP, UBL (external)",2,variable,no ENSG00000162402,USP24,Ubiquitin and UBL,"Armadillo-type, UBA, UBL (external)",3,variable,no ENSG00000115464,USP34,Ubiquitin and UBL,"Armadillo-type, UBL (external)",0,variable,no ENSG00000085982,USP40,Ubiquitin and UBL,UBL (external),1,variable,no ENSG00000124486,USP9X,Ubiquitin and UBL,"Armadillo-type, UBL (external)",1,variable,yes ENSG00000114374,USP9Y,Ubiquitin and UBL,"Armadillo-type, UBL (external)",7,variable,yes ENSG00000187555,USP7,Ubiquitin and UBL,"MATH-TRAF, UBL (external)",0,core,yes ENSG00000170242,USP47,Ubiquitin and UBL,UBL (external),2,variable,no ENSG00000154914,USP43,Ubiquitin and UBL,UBL (internal),20,variable,no ENSG00000103404,USP31,Ubiquitin and UBL,UBL (internal),7,variable,no ENSG00000172046,USP19,Ubiquitin and UBL,UBL (internal),1,variable,no ENSG00000170832,USP32,Ubiquitin and UBL,"DUSP, UBLs (internal, external)",2,variable,no ENSG00000114316,USP4,Ubiquitin and UBL,"DUSP, UBLs (internal, external)",1,variable,no ENSG00000102226,USP11,Ubiquitin and UBL,"DUSP, UBLs (internal, external)",5,variable,no ENSG00000135655,USP15,Ubiquitin and UBL,"DUSP, UBLs (internal, external)",2,variable,no ENSG00000118503,TNFAIP3,Ubiquitin and UBL,A20,9,variable,yes ENSG00000077254,USP33,Ubiquitin and UBL,"DUSP, UBP-ZnF",1,variable,no ENSG00000136878,USP20,Ubiquitin and UBL,"DUSP, UBP-ZnF",1,variable,no ENSG00000111667,USP5,Ubiquitin and UBL,"UBP-ZnF, UBA",1,variable,no ENSG00000058056,USP13,Ubiquitin and UBL,"UBP-ZnF, UBA",6,variable,no ENSG00000140455,USP3,Ubiquitin and UBL,UBP-ZnF,3,variable,no ENSG00000156256,USP16,Ubiquitin and UBL,UBP-ZnF,1,variable,no ENSG00000124422,USP22,Ubiquitin and UBL,UBP-ZnF,3,variable,no ENSG00000168883,USP39,Ubiquitin and UBL,UBP-ZnF,1,variable,no ENSG00000136014,USP44,Ubiquitin and UBL,UBP-ZnF,9,variable,no ENSG00000123552,USP45,Ubiquitin and UBL,UBP-ZnF,3,variable,yes ENSG00000164663,USP49,Ubiquitin and UBL,UBP-ZnF,0,variable,no ENSG00000247746,USP51,Ubiquitin and UBL,UBP-ZnF,4,variable,no ENSG00000048028,USP28,Ubiquitin and UBL,UBA,5,variable,no ENSG00000155313,USP25,Ubiquitin and UBL,"UBA, UIM",3,variable,no ENSG00000135913,USP37,Ubiquitin and UBL,"PH-like, UIM",1,variable,no ENSG00000131864,USP29,Ubiquitin and UBL,PH-like,2,variable,no ENSG00000118369,USP35,Ubiquitin and UBL,Armadillo-type,3,variable,no ENSG00000129204,USP6,Ubiquitin and UBL,Rab-GTPase-TBC,7,variable,no ENSG00000138592,USP8,Ubiquitin and UBL,"dimerization, rhodanese-like ",0,variable,yes ENSG00000103194,USP10,Ubiquitin and UBL,"Ataxin-2, C term",2,variable,no ENSG00000083799,CYLD,Ubiquitin and UBL,CAP Gly-rich domain,1,variable,yes ENSG00000055483,USP36,Ubiquitin and UBL,"assorted, large",1,variable,no ENSG00000170185,USP38,Ubiquitin and UBL,"assorted, large",1,variable,no ENSG00000106346,USP42,Ubiquitin and UBL,"assorted, large",1,variable,no ENSG00000145390,USP53,Ubiquitin and UBL,"assorted, large",8,variable,no ENSG00000166348,USP54,Ubiquitin and UBL,"assorted, large",8,variable,no ENSG00000162607,USP1,Ubiquitin and UBL,assorted,1,variable,no ENSG00000036672,USP2,Ubiquitin and UBL,assorted,16,variable,no ENSG00000152484,USP12,Ubiquitin and UBL,assorted,1,variable,no ENSG00000184979,USP18,Ubiquitin and UBL,assorted,3,variable,yes ENSG00000143258,USP21,Ubiquitin and UBL,assorted,0,core,no ENSG00000273820,USP27X,Ubiquitin and UBL,assorted,7,variable,yes ENSG00000135093,USP30,Ubiquitin and UBL,assorted,1,variable,no ENSG00000109189,USP46,Ubiquitin and UBL,assorted,7,variable,no ENSG00000170236,USP50,Ubiquitin and UBL,assorted,10,variable,no ENSG00000132952,USPL1,Ubiquitin and UBL,deSUMOylation,1,variable,no ENSG00000118939,UCHL3,Ubiquitin and UBL,nan,4,variable,no ENSG00000163930,BAP1,Ubiquitin and UBL,nan,3,variable,yes ENSG00000154277,UCHL1,Ubiquitin and UBL,nan,22,variable,yes ENSG00000121022,COPS5,Ubiquitin and UBL,CSN complex,2,variable,no ENSG00000185515,BRCC3,Ubiquitin and UBL,assorted,2,variable,no ENSG00000124356,STAMBP,Ubiquitin and UBL,assorted,1,variable,yes ENSG00000138134,STAMBPL1,Ubiquitin and UBL,assorted,9,variable,no ENSG00000008382,MPND,Ubiquitin and UBL,assorted,3,variable,no ENSG00000162601,MYSM1,Ubiquitin and UBL,assorted,1,variable,yes ENSG00000019995,ZRANB1,Ubiquitin and UBL,RanBP2-type ZnF,1,variable,no ENSG00000101901,ALG13,Ubiquitin and UBL,assorted,0,variable,yes ENSG00000089723,OTUB2,Ubiquitin and UBL,assorted,11,variable,no ENSG00000165312,OTUD1,Ubiquitin and UBL,assorted,2,variable,no ENSG00000169914,OTUD3,Ubiquitin and UBL,assorted,2,variable,no ENSG00000164164,OTUD4,Ubiquitin and UBL,assorted,2,variable,no ENSG00000068308,OTUD5,Ubiquitin and UBL,assorted,2,variable,no ENSG00000189401,OTUD6A,Ubiquitin and UBL,assorted,1,variable,no ENSG00000155100,OTUD6B,Ubiquitin and UBL,assorted,1,variable,yes ENSG00000154124,OTULIN,Ubiquitin and UBL,assorted,5,variable,yes ENSG00000143409,MINDY1,Ubiquitin and UBL,nan,3,variable,no ENSG00000128923,MINDY2,Ubiquitin and UBL,nan,4,variable,no ENSG00000148481,MINDY3,Ubiquitin and UBL,nan,1,variable,no ENSG00000106125,MINDY4,Ubiquitin and UBL,nan,8,variable,no ENSG00000100221,JOSD1,Ubiquitin and UBL,non-UIM,1,variable,no ENSG00000161677,JOSD2,Ubiquitin and UBL,non-UIM,2,variable,no ENSG00000153975,ZUFSP,Ubiquitin and UBL,DUB,0,variable,no ENSG00000109775,UFSP2,Ubiquitin and UBL,deURMylase,2,variable,yes ENSG00000079387,SENP1,Ubiquitin and UBL,deSUMOylase,1,variable,no ENSG00000163904,SENP2,Ubiquitin and UBL,deSUMOylase,1,variable,no ENSG00000161956,SENP3,Ubiquitin and UBL,deSUMOylase,0,core,no ENSG00000119231,SENP5,Ubiquitin and UBL,deSUMOylase,0,variable,no ENSG00000112701,SENP6,Ubiquitin and UBL,deSUMOylase,0,core,no ENSG00000138468,SENP7,Ubiquitin and UBL,deSUMOylase,1,variable,no ENSG00000166192,SENP8,Ubiquitin and UBL,"deNEDDylase, NEDD8 processing",4,variable,no ENSG00000168090,COPS6,Ubiquitin and UBL,deNEDDylase,0,core,no ENSG00000166200,COPS2,Ubiquitin and UBL,deNEDDylase,2,variable,no ENSG00000141030,COPS3,Ubiquitin and UBL,deNEDDylase,1,variable,no ENSG00000138663,COPS4,Ubiquitin and UBL,deNEDDylase,1,variable,no ENSG00000111652,COPS7A,Ubiquitin and UBL,deNEDDylase,3,variable,no ENSG00000144524,COPS7B,Ubiquitin and UBL,deNEDDylase,0,core,no ENSG00000198612,COPS8,Ubiquitin and UBL,deNEDDylase,2,variable,no ENSG00000169727,GPS1,Ubiquitin and UBL,deNEDDylase,0,core,no ENSG00000175166,PSMD2,Ubiquitin and UBL,regulatory particle,1,variable,no ENSG00000159352,PSMD4,Ubiquitin and UBL,regulatory particle,1,variable,no ENSG00000130706,ADRM1,Ubiquitin and UBL,regulatory particle,1,variable,no ENSG00000197312,DDI2,Ubiquitin and UBL,protease,4,variable,no ENSG00000178381,ZFAND2A,Ubiquitin and UBL,UBZ,3,variable,no ENSG00000158552,ZFAND2B,Ubiquitin and UBL,"UIM, UBZ",2,variable,no ENSG00000107372,ZFAND5,Ubiquitin and UBL,A20,2,variable,no ENSG00000179262,RAD23A,Ubiquitin and UBL,with STI1,1,variable,no ENSG00000119318,RAD23B,Ubiquitin and UBL,with STI1,1,variable,no ENSG00000135018,UBQLN1,Ubiquitin and UBL,with STI1,0,core,no ENSG00000188021,UBQLN2,Ubiquitin and UBL,with STI1,1,variable,yes ENSG00000175520,UBQLN3,Ubiquitin and UBL,with STI1,4,variable,no ENSG00000160803,UBQLN4,Ubiquitin and UBL,with STI1,2,variable,no ENSG00000182446,NPLOC4,Ubiquitin and UBL,MPN & UBL,1,variable,no ENSG00000130939,UBE4B,Ubiquitin and UBL,RING,2,variable,no ENSG00000159461,AMFR,Ubiquitin and UBL,RING,1,variable,no ENSG00000092098,RNF31,Ubiquitin and UBL,RBR,1,variable,no ENSG00000010072,SPRTN,Ubiquitin and UBL,endopeptidase,1,variable,yes ENSG00000144468,RHBDD1,Ubiquitin and UBL,serine protease,1,variable,no ENSG00000137055,PLAA,Ubiquitin and UBL,PFUC,1,variable,yes ENSG00000070010,UFD1L,Ubiquitin and UBL,ERAD cofactor,0,core,no ENSG00000088833,NSFL1C,Ubiquitin and UBL,UBA,1,variable,no ENSG00000163960,UBXN7,Ubiquitin and UBL,"UBA, UIM",0,variable,no ENSG00000185104,FAF1,Ubiquitin and UBL,"UBA, SIM",2,variable,no ENSG00000113194,FAF2,Ubiquitin and UBL,UBA,0,variable,no ENSG00000013374,NUB1,Ubiquitin and UBL,lacking STI1,0,core,no ENSG00000162191,UBXN1,Ubiquitin and UBL,UBA,1,variable,no ENSG00000179526,SHARPIN,Ubiquitin and UBL,with UBL,2,variable,no ENSG00000125826,RBCK1,Ubiquitin and UBL,RING,1,variable,yes ENSG00000130560,UBAC1,Ubiquitin and UBL,with STI1,1,variable,no ENSG00000138629,UBL7,Ubiquitin and UBL,lacking STI1,1,variable,no ENSG00000223573,TINCR,Ubiquitin and UBL,lacking STI1,20,variable,no ENSG00000077721,UBE2A,Ubiquitin and UBL,backside Ub binding,2,variable,yes ENSG00000119048,UBE2B,Ubiquitin and UBL,backside Ub binding,1,variable,no ENSG00000072401,UBE2D1,Ubiquitin and UBL,backside Ub binding,5,variable,no ENSG00000131508,UBE2D2,Ubiquitin and UBL,backside Ub binding,0,core,no ENSG00000109332,UBE2D3,Ubiquitin and UBL,backside Ub binding,1,variable,no ENSG00000078967,UBE2D4,Ubiquitin and UBL,backside Ub binding,3,variable,no ENSG00000132388,UBE2G1,Ubiquitin and UBL,backside Ub binding,2,variable,no ENSG00000184787,UBE2G2,Ubiquitin and UBL,backside Ub binding,2,variable,no ENSG00000170035,UBE2E3,Ubiquitin and UBL,backside Ub binding,1,variable,no ENSG00000160714,UBE2Q1,Ubiquitin and UBL,RWD,0,core,no ENSG00000140367,UBE2Q2,Ubiquitin and UBL,RWD,2,variable,no ENSG00000078140,UBE2K,Ubiquitin and UBL,UBA,0,core,no ENSG00000175931,UBE2O,Ubiquitin and UBL,idiosyncratic E3 ligase,0,core,no ENSG00000103275,UBE2I,Ubiquitin and UBL,backside SUMO binding,0,core,no ENSG00000176248,ANAPC2,Ubiquitin and UBL,APC,0,core,no ENSG00000141552,ANAPC11,Ubiquitin and UBL,APC,1,variable,no ENSG00000086758,HUWE1,Ubiquitin and UBL,HECT,1,variable,yes ENSG00000128731,HERC2,Ubiquitin and UBL,HECT,1,variable,yes ENSG00000104517,UBR5,Ubiquitin and UBL,HECT & UBR,0,core,no ENSG00000112659,CUL9,Ubiquitin and UBL,RBR & CULLIN,0,variable,no ENSG00000103091,WDR59,Ubiquitin and UBL,GATOR2 complex,1,variable,no ENSG00000001629,ANKIB1,Ubiquitin and UBL,RBR,0,variable,no ENSG00000166233,ARIH1,Ubiquitin and UBL,RBR,1,variable,no ENSG00000177479,ARIH2,Ubiquitin and UBL,RBR,1,variable,no ENSG00000013561,RNF14,Ubiquitin and UBL,RBR,1,variable,no ENSG00000011275,RNF216,Ubiquitin and UBL,RBR,1,variable,yes ENSG00000132256,TRIM5,Ubiquitin and UBL,RING,8,variable,no ENSG00000140464,PML,Ubiquitin and UBL,RING,7,variable,yes ENSG00000110330,BIRC2,Ubiquitin and UBL,RING,0,core,no ENSG00000023445,BIRC3,Ubiquitin and UBL,RING,7,variable,no ENSG00000163098,BIRC8,Ubiquitin and UBL,RING,1,variable,no ENSG00000101966,XIAP,Ubiquitin and UBL,RING,1,variable,yes ENSG00000089234,BRAP,Ubiquitin and UBL,RING,1,variable,no ENSG00000110395,CBL,Ubiquitin and UBL,RING,5,variable,yes ENSG00000114423,CBLB,Ubiquitin and UBL,RING,5,variable,no ENSG00000135679,MDM2,Ubiquitin and UBL,RING,2,variable,yes ENSG00000198625,MDM4,Ubiquitin and UBL,RING,1,variable,yes ENSG00000070950,RAD18,Ubiquitin and UBL,RING,0,variable,no ENSG00000124226,RNF114,Ubiquitin and UBL,RING,1,variable,no ENSG00000101695,RNF125,Ubiquitin and UBL,RING,10,variable,yes ENSG00000134758,RNF138,Ubiquitin and UBL,RING,2,variable,no ENSG00000158717,RNF166,Ubiquitin and UBL,RING,2,variable,no ENSG00000176407,KCMF1,Ubiquitin and UBL,idiosyncratic E3 ligase,1,variable,no ENSG00000186187,ZNRF1,Ubiquitin and UBL,RING,3,variable,no ENSG00000180233,ZNRF2,Ubiquitin and UBL,RING,2,variable,no ENSG00000198862,LTN1,Ubiquitin and UBL,RING,0,variable,no ENSG00000163481,RNF25,Ubiquitin and UBL,RING,0,core,no ENSG00000182670,TTC3,Ubiquitin and UBL,RING,5,variable,no ENSG00000020426,MNAT1,Ubiquitin and UBL,RING,2,variable,no ENSG00000115392,FANCL,Ubiquitin and UBL,RING,4,variable,no ENSG00000198919,DZIP3,Ubiquitin and UBL,RING,6,variable,no ENSG00000063978,RNF4,Ubiquitin and UBL,RING,0,core,no ENSG00000157450,RNF111,Ubiquitin and UBL,RING,0,variable,no ENSG00000163961,RNF168,Ubiquitin and UBL,RING,1,variable,yes ENSG00000166439,RNF169,Ubiquitin and UBL,RING,2,variable,no ENSG00000167257,RNF214,Ubiquitin and UBL,RING,1,variable,no ENSG00000187147,RNF220,Ubiquitin and UBL,RING,2,variable,no ENSG00000033800,PIAS1,Ubiquitin and UBL,SIM,1,variable,no ENSG00000078043,PIAS2,Ubiquitin and UBL,SIM,4,variable,no ENSG00000105229,PIAS4,Ubiquitin and UBL,SIM,2,variable,no ENSG00000153201,RANBP2,Ubiquitin and UBL,RanBP2-type ZnF & SIM,0,core,yes ENSG00000141582,CBX4,Ubiquitin and UBL,SIM,3,variable,no ENSG00000112200,ZNF451,Ubiquitin and UBL,"UIM, SIM",0,variable,no ENSG00000043093,DCUN1D1,Ubiquitin and UBL,UBA,1,variable,no ENSG00000150401,DCUN1D2,Ubiquitin and UBL,UBA,5,variable,no ENSG00000103326,CAPN15,Ubiquitin and UBL,endopeptidase,2,variable,no ENSG00000156639,ZFAND3,Ubiquitin and UBL,A20,2,variable,no ENSG00000086666,ZFAND6,Ubiquitin and UBL,A20,1,variable,no ENSG00000115307,AUP1,Ubiquitin and UBL,ERAD cofactor,1,variable,no ENSG00000135924,DNAJB2,Ubiquitin and UBL,HSP70 cochaperone,1,variable,yes ENSG00000204209,DAXX,Ubiquitin and UBL,protein folding & quality control,1,variable,no ENSG00000244687,UBE2V1,Ubiquitin and UBL,"UEV, backside Ub binding",0,core,no ENSG00000169139,UBE2V2,Ubiquitin and UBL,"UEV, backside Ub binding",2,variable,no ENSG00000087206,UIMC1,Ubiquitin and UBL,RAP80 NTD,2,variable,no ENSG00000122481,RWDD3,Ubiquitin and UBL,RWD domain,2,variable,no ENSG00000100418,DESI1,Ubiquitin and UBL,PPPDE,1,variable,no ENSG00000136560,TANK,Ubiquitin and UBL,nan,2,variable,no ENSG00000116141,MARK1,Ubiquitin and UBL,microtubule-associated Ser/Thr kinases,7,variable,no ENSG00000072518,MARK2,Ubiquitin and UBL,microtubule-associated Ser/Thr kinases,2,variable,no ENSG00000075413,MARK3,Ubiquitin and UBL,microtubule-associated Ser/Thr kinases,0,core,yes ENSG00000007047,MARK4,Ubiquitin and UBL,microtubule-associated Ser/Thr kinases,1,variable,no ENSG00000132356,PRKAA1,Ubiquitin and UBL,AMP-activated Ser/Thr kinases,1,variable,no ENSG00000162409,PRKAA2,Ubiquitin and UBL,AMP-activated Ser/Thr kinases,10,variable,no ENSG00000142178,SIK1,Ubiquitin and UBL,salt-inducible Ser/Thr kinases,10,variable,yes ENSG00000170145,SIK2,Ubiquitin and UBL,salt-inducible Ser/Thr kinases,5,variable,no ENSG00000160584,SIK3,Ubiquitin and UBL,salt-inducible Ser/Thr kinases,1,variable,yes ENSG00000160469,BRSK1,Ubiquitin and UBL,other Ser/Thr kinase,20,variable,no ENSG00000174672,BRSK2,Ubiquitin and UBL,other Ser/Thr kinase,24,variable,no ENSG00000131023,LATS1,Ubiquitin and UBL,other Ser/Thr kinase,0,variable,no ENSG00000150457,LATS2,Ubiquitin and UBL,other Ser/Thr kinase,9,variable,no ENSG00000174292,TNK1,Ubiquitin and UBL,other Ser/Thr kinase,12,variable,no ENSG00000061938,TNK2,Ubiquitin and UBL,other Ser/Thr kinase,4,variable,no ENSG00000163788,SNRK,Ubiquitin and UBL,other Ser/Thr kinase,1,variable,no ENSG00000101782,RIOK3,Ubiquitin and UBL,other Ser/Thr kinase,4,variable,no ENSG00000128829,EIF2AK4,Ubiquitin and UBL,other Ser/Thr kinase,1,variable,yes ENSG00000123374,CDK2,Ubiquitin and UBL,other Ser/Thr kinase,7,variable,no ENSG00000064393,HIPK2,Ubiquitin and UBL,other Ser/Thr kinase,10,variable,no ENSG00000166851,PLK1,Ubiquitin and UBL,other Ser/Thr kinase,5,variable,no ENSG00000154127,UBASH3B,Ubiquitin and UBL,Tyr phosphatase,16,variable,no ENSG00000160185,UBASH3A,Ubiquitin and UBL,Tyr phosphatase,12,variable,no ENSG00000142002,DPP9,Ubiquitin and UBL,dipeptidyl peptidase,4,variable,no ENSG00000094631,HDAC6,Ubiquitin and UBL,histone deacetylase,2,variable,yes ENSG00000242028,HYPK,Ubiquitin and UBL,N-terminal acetylation,3,variable,no ENSG00000178685,PARP10,Ubiquitin and UBL,ADP ribosyltransferase,6,variable,no ENSG00000138778,CENPE,Ubiquitin and UBL,SIM,6,variable,yes ENSG00000147130,ZMYM3,Ubiquitin and UBL,SIM,0,core,no ENSG00000124789,NUP153,Ubiquitin and UBL,RanBP2-type ZnF,0,core,no ENSG00000170734,POLH,Ubiquitin and UBL,DNA polymerase,1,variable,yes ENSG00000122008,POLK,Ubiquitin and UBL,DNA polymerase,1,variable,no ENSG00000101751,POLI,Ubiquitin and UBL,DNA polymerase,2,variable,no ENSG00000135945,REV1,Ubiquitin and UBL,dCTP transferase,1,variable,no ENSG00000188827,SLX4,Ubiquitin and UBL,DNA endonuclease cofactor,2,variable,yes ENSG00000198924,DCLRE1A,Ubiquitin and UBL,DNA exonuclease,1,variable,no ENSG00000198690,FAN1,Ubiquitin and UBL,DNA exonuclease,2,variable,yes ENSG00000162585,FAAP20,Ubiquitin and UBL,DNA repair accessory,0,variable,no ENSG00000152422,XRCC4,Ubiquitin and UBL,DNA repair accessory,1,variable,yes ENSG00000139372,TDG,Ubiquitin and UBL,DNA glycosylase,2,variable,no ENSG00000111802,TDP2,Ubiquitin and UBL,5'-tyrosyl DNA phosphodiesterase,1,variable,yes ENSG00000137073,UBAP2,Ubiquitin and UBL,RNA polymerase II removal,2,variable,no ENSG00000143569,UBAP2L,Ubiquitin and UBL,RNA polymerase II removal,0,core,no ENSG00000035928,RFC1,Ubiquitin and UBL,DNA polymerase clamp loader,0,variable,yes ENSG00000124535,WRNIP1,Ubiquitin and UBL,DNA polymerase accessory,0,core,no ENSG00000078177,N4BP2,Ubiquitin and UBL,DNA nicking endonuclease,3,variable,no ENSG00000163104,SMARCAD1,Ubiquitin and UBL,chromatin remodeling,1,variable,yes ENSG00000089280,FUS,Ubiquitin and UBL,DNA/RNA binding protein,0,core,yes ENSG00000270647,TAF15,Ubiquitin and UBL,initiation,0,core,no ENSG00000182944,EWSR1,Ubiquitin and UBL,repression,0,core,yes ENSG00000163602,RYBP,Ubiquitin and UBL,repression,1,variable,no ENSG00000268629,TEX13A,Ubiquitin and UBL,repression,1,variable,no ENSG00000282419,TEX13D,Ubiquitin and UBL,repression,11,variable,no ENSG00000015153,YAF2,Ubiquitin and UBL,coactivation and corepression,2,variable,no ENSG00000163635,ATXN7,Ubiquitin and UBL,activation,1,variable,yes ENSG00000087152,ATXN7L3,Ubiquitin and UBL,activation,1,variable,no ENSG00000064218,DMRT3,Ubiquitin and UBL,activation (probable),26,variable,no ENSG00000176399,DMRTA1,Ubiquitin and UBL,DNA binding,16,variable,no ENSG00000083544,TDRD3,Ubiquitin and UBL,activation,1,variable,no ENSG00000171681,ATF7IP,Ubiquitin and UBL,activation and repression,1,variable,no ENSG00000005339,CREBBP,Ubiquitin and UBL,activation,0,core,yes ENSG00000174460,ZCCHC12,Ubiquitin and UBL,coactivation,28,variable,no ENSG00000136826,KLF4,Ubiquitin and UBL,activation and repression,12,variable,no ENSG00000182979,MTA1,Ubiquitin and UBL,coactivation and corepression,0,core,no ENSG00000137693,YAP1,Ubiquitin and UBL,coactivation and corepression,11,variable,yes ENSG00000143379,SETDB1,Ubiquitin and UBL,repression,0,variable,no ENSG00000121741,ZMYM2,Ubiquitin and UBL,repression,0,core,no ENSG00000089902,RCOR1,Ubiquitin and UBL,corepression,3,variable,no ENSG00000003756,RBM5,Ubiquitin and UBL,mRNA splicing,0,core,no ENSG00000004534,RBM6,Ubiquitin and UBL,mRNA splicing,0,core,no ENSG00000182872,RBM10,Ubiquitin and UBL,mRNA splicing,1,variable,yes ENSG00000132485,ZRANB2,Ubiquitin and UBL,mRNA splicing,1,variable,no ENSG00000177483,RBM44,Ubiquitin and UBL,mRNA splicing,8,variable,no ENSG00000172062,SMN1,Ubiquitin and UBL,mRNA splicing,0,variable,yes ENSG00000174231,PRPF8,Ubiquitin and UBL,mRNA splicing,0,core,yes ENSG00000162231,NXF1,Ubiquitin and UBL,UBA,1,variable,no ENSG00000163874,ZC3H12A,Ubiquitin and UBL,UBA,15,variable,no ENSG00000102053,ZC3H12B,Ubiquitin and UBL,UBA,8,variable,no ENSG00000149289,ZC3H12C,Ubiquitin and UBL,UBA,4,variable,no ENSG00000078687,TNRC6C,Ubiquitin and UBL,repression,2,variable,no ENSG00000100325,ASCC2,Ubiquitin and UBL,ribosome QC & DNA repair,4,variable,no ENSG00000103671,TRIP4,Ubiquitin and UBL,ribosome QC & transcriptional activation,0,variable,yes ENSG00000112339,HBS1L,Ubiquitin and UBL,translation QC factor,2,variable,no ENSG00000196531,NACA,Ubiquitin and UBL,nascent peptide binding,2,variable,no ENSG00000136274,NACAD,Ubiquitin and UBL,nascent peptide binding,13,variable,no ENSG00000253506,NACA2,Ubiquitin and UBL,nascent peptide binding,2,variable,no ENSG00000123297,TSFM,Ubiquitin and UBL,mitochondrial,3,variable,yes ENSG00000114735,HEMK1,Ubiquitin and UBL,mitochondrial,3,variable,no ENSG00000154059,IMPACT,Ubiquitin and UBL,translational upregulation,2,variable,no ENSG00000269335,IKBKG,Ubiquitin and UBL,UBAN & NEMO-type ZnF,1,variable,yes ENSG00000168884,TNIP2,Ubiquitin and UBL,UBAN & NEMO-type ZnF,4,variable,no ENSG00000145901,TNIP1,Ubiquitin and UBL,UBAN,4,variable,no ENSG00000198933,TBKBP1,Ubiquitin and UBL,UBZ,4,variable,no ENSG00000055208,TAB2,Ubiquitin and UBL,RanBP2-type ZnF,1,variable,yes ENSG00000157625,TAB3,Ubiquitin and UBL,RanBP2-type ZnF,2,variable,no ENSG00000146776,ATXN7L1,Ubiquitin and UBL,SCA7,4,variable,no ENSG00000162650,ATXN7L2,Ubiquitin and UBL,SCA7,6,variable,no ENSG00000111832,RWDD1,Ubiquitin and UBL,RWD domain,3,variable,no ENSG00000013392,RWDD2A,Ubiquitin and UBL,RWD domain,6,variable,no ENSG00000156253,RWDD2B,Ubiquitin and UBL,RWD domain,2,variable,no ENSG00000182552,RWDD4,Ubiquitin and UBL,RWD domain,3,variable,no ENSG00000163214,DHX57,Ubiquitin and UBL,"UBA, RWD domain",1,variable,no ENSG00000102921,N4BP1,Ubiquitin and UBL,UBA,3,variable,no ENSG00000100441,KHNYN,Ubiquitin and UBL,UBA,4,variable,no ENSG00000134882,UBAC2,Ubiquitin and UBL,UBA,1,variable,no ENSG00000180891,CUEDC1,Ubiquitin and UBL,UBA,5,variable,no ENSG00000107874,CUEDC2,Ubiquitin and UBL,UBA,1,variable,no ENSG00000196821,C6orf106,Ubiquitin and UBL,UBA,1,variable,no ENSG00000123352,SPATS2,Ubiquitin and UBL,UBA,3,variable,no ENSG00000196141,SPATS2L,Ubiquitin and UBL,UBA,4,variable,no ENSG00000153443,UBALD1,Ubiquitin and UBL,UBA,1,variable,no ENSG00000185262,UBALD2,Ubiquitin and UBL,UBA,3,variable,no ENSG00000246922,UBAP1L,Ubiquitin and UBL,UBA,2,variable,no ENSG00000100263,RHBDD3,Ubiquitin and UBL,UBA & UIM,1,variable,no ENSG00000229547,UBE2DNL,Ubiquitin and UBL,UEV,3,variable,no ENSG00000091844,RGS17,Ubiquitin and UBL,SIM,12,variable,no ENSG00000185345,PARK2,Ubiquitin and UBL,E3 ligases,10,variable,no ENSG00000170967,DDI1,Ubiquitin and UBL,assorted enzymes ,3,variable,no ENSG00000204463,BAG6,Ubiquitin and UBL,chaperones and related,3,variable,no ENSG00000175518,UBQLNL,Ubiquitin and UBL,ubiquilin adjacent,11,variable,no ENSG00000167470,MIDN,Ubiquitin and UBL,non-enzymes,6,variable,no ENSG00000169696,ASPSCR1,Ubiquitin and UBL,adaptors,1,variable,yes ENSG00000173960,UBXN2A,Ubiquitin and UBL,adaptors,3,variable,no ENSG00000215114,UBXN2B,Ubiquitin and UBL,adaptors,2,variable,no ENSG00000158062,UBXN11,Ubiquitin and UBL,adaptors,7,variable,no ENSG00000144224,UBXN4,Ubiquitin and UBL,adaptors,0,core,no ENSG00000167671,UBXN6,Ubiquitin and UBL,adaptors,2,variable,no ENSG00000104691,UBXN8,Ubiquitin and UBL,adaptors,5,variable,no ENSG00000162543,UBXN10,Ubiquitin and UBL,adaptors,15,variable,no ENSG00000170315,UBB,Ubiquitin and UBL,polyubiquitin,3,variable,no ENSG00000150991,UBC,Ubiquitin and UBL,polyubiquitin,2,variable,no ENSG00000143947,RPS27A,Ubiquitin and UBL,ribosomal ubiquitin fusion,2,variable,no ENSG00000221983,UBA52,Ubiquitin and UBL,ribosomal ubiquitin fusion,1,variable,no ENSG00000187608,ISG15,Ubiquitin and UBL,ISG15,4,variable,yes ENSG00000129559,NEDD8,Ubiquitin and UBL,NEDD8,1,variable,no ENSG00000116030,SUMO1,Ubiquitin and UBL,SUMO,0,core,yes ENSG00000188612,SUMO2,Ubiquitin and UBL,SUMO,0,core,no ENSG00000184900,SUMO3,Ubiquitin and UBL,SUMO,0,core,no ENSG00000241721,SUMO1P1,Ubiquitin and UBL,SUMO,4,variable,no ENSG00000120686,UFM1,Ubiquitin and UBL,UFM1,2,variable,yes ENSG00000167118,URM1,Ubiquitin and UBL,URM1,0,core,no ENSG00000198258,UBL5,Ubiquitin and UBL,UBL5,0,core,no ENSG00000122042,UBL3,Ubiquitin and UBL,UBL3,3,variable,no ENSG00000149806,FAU,Ubiquitin and UBL,FAU,1,variable,no ENSG00000126261,UBA2,Ubiquitin and UBL,SUMO activation ,0,core,no ENSG00000103363,ELOB,Ubiquitin and UBL,E3 ligases,0,core,no ENSG00000204227,RING1,Ubiquitin and UBL,E3 ligases,0,core,no ENSG00000121481,RNF2,Ubiquitin and UBL,E3 ligases,0,variable,no ENSG00000168283,BMI1,Ubiquitin and UBL,E3 ligases,1,variable,no ENSG00000115289,PCGF1,Ubiquitin and UBL,E3 ligases,0,core,no ENSG00000277258,PCGF2,Ubiquitin and UBL,E3 ligases,4,variable,yes ENSG00000185619,PCGF3,Ubiquitin and UBL,E3 ligases,0,core,no ENSG00000180628,PCGF5,Ubiquitin and UBL,E3 ligases,2,variable,no ENSG00000156374,PCGF6,Ubiquitin and UBL,E3 ligases,1,variable,no ENSG00000276043,UHRF1,Ubiquitin and UBL,E3 ligases,10,variable,no ENSG00000147854,UHRF2,Ubiquitin and UBL,E3 ligases,0,variable,no ENSG00000100225,FBXO7,Ubiquitin and UBL,E3 ligases,2,variable,yes ENSG00000114742,WDR48,Ubiquitin and UBL,DUB modulator,0,variable,no ENSG00000051108,HERPUD1,Ubiquitin and UBL,ubiquilin adjacent,4,variable,no ENSG00000122557,HERPUD2,Ubiquitin and UBL,ubiquilin adjacent,1,variable,no ENSG00000107262,BAG1,Ubiquitin and UBL,chaperones and related,2,variable,no ENSG00000151835,SACS,Ubiquitin and UBL,chaperones and related,7,variable,yes ENSG00000102178,UBL4A,Ubiquitin and UBL,chaperones and related,3,variable,no ENSG00000186150,UBL4B,Ubiquitin and UBL,chaperones and related,14,variable,no ENSG00000105254,TBCB,Ubiquitin and UBL,chaperones and related,2,variable,no ENSG00000154114,TBCEL,Ubiquitin and UBL,chaperones and related,1,variable,no ENSG00000164332,UBLCP1,Ubiquitin and UBL,assorted enzymes ,0,core,no ENSG00000213341,CHUK,Ubiquitin and UBL,assorted enzymes ,0,variable,yes ENSG00000104365,IKBKB,Ubiquitin and UBL,assorted enzymes ,2,variable,yes ENSG00000263528,IKBKE,Ubiquitin and UBL,assorted enzymes ,11,variable,no ENSG00000183735,TBK1,Ubiquitin and UBL,assorted enzymes ,0,core,yes ENSG00000099797,TECR,Ubiquitin and UBL,assorted enzymes ,2,variable,yes ENSG00000205678,TECRL,Ubiquitin and UBL,assorted enzymes ,21,variable,yes ENSG00000172671,ZFAND4,Ubiquitin and UBL,non-enzymes,3,variable,no ENSG00000106078,COBL,Ubiquitin and UBL,non-enzymes,18,variable,no ENSG00000082438,COBLL1,Ubiquitin and UBL,non-enzymes,12,variable,no ENSG00000164897,TMUB1,Ubiquitin and UBL,non-enzymes,2,variable,no ENSG00000168591,TMUB2,Ubiquitin and UBL,non-enzymes,1,variable,no ENSG00000124227,ANKRD60,Ubiquitin and UBL,non-enzymes,1,variable,no ENSG00000103353,UBFD1,Ubiquitin and UBL,non-enzymes,2,variable,no ENSG00000164675,IQUB,Ubiquitin and UBL,non-enzymes,9,variable,no ENSG00000165886,UBTD1,Ubiquitin and UBL,non-enzymes,3,variable,no ENSG00000168246,UBTD2,Ubiquitin and UBL,non-enzymes,3,variable,no ENSG00000143751,SDE2,Ubiquitin and UBL,nucleic acid processes,1,variable,no ENSG00000176953,NFATC2IP,Ubiquitin and UBL,nucleic acid processes,0,core,no ENSG00000135114,OASL,Ubiquitin and UBL,nucleic acid processes,8,variable,no ENSG00000099995,SF3A1,Ubiquitin and UBL,nucleic acid processes,1,variable,no ENSG00000161981,SNRNP25,Ubiquitin and UBL,nucleic acid processes,6,variable,no