ENSG,Name,Class,Group,Type,Subtype,Gene names,above 5 TPM yes/no,Uniprot swiss ID
ENSG00000075785,RAB7A,Autophagic lysosome reformation,Lysosomal tubulation,nan,nan,"RAB7A,CMT2B,PRO2706,RAB7",yes,P51149
ENSG00000276600,RAB7B,Autophagic lysosome reformation,Lysosomal tubulation,nan,nan,"RAB7B,RAB7",yes,Q96AH8
ENSG00000072121,ZFYVE26,Autophagic lysosome reformation,Specific function in autophagic lysosome reformation unknown,nan,nan,"ZFYVE26,FYVE-CENT,SPG15",yes,Q68DK2
ENSG00000170759,KIF5B,Autophagic lysosome reformation,Lysosomal tubulation,nan,nan,"KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC",yes,P33176
ENSG00000177628,GBA,Autophagic lysosome reformation,Specific function in autophagic lysosome reformation unknown,nan,nan,"GBA,GBA1,GCB,GLUC",yes,P04062
ENSG00000107242,PIP5K1B,Autophagic lysosome reformation,Regulation of autolysosome membrane composition,nan,nan,"PIP5K1B,MSS4,STM7",yes,O14986
ENSG00000185896,LAMP1,Autophagic lysosome reformation,Regulation of autolysosome morphology,nan,nan,"LAMP1,CD107a,LAMPA,LGP120",yes,P11279
ENSG00000169682,SPNS1,Autophagic lysosome reformation,Efflux of autophagy products,nan,nan,"SPNS1,HSpin1,LAT,PP2030,SLC62A1,SPIN1,SPINL,nrs",yes,Q9H2V7
ENSG00000104133,SPG11,Autophagic lysosome reformation,Specific function in autophagic lysosome reformation unknown,nan,nan,"SPG11,ALS5,CMT2X,KIAA1840",yes,Q96JI7
ENSG00000157020,SEC13,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC13,D3S1231E,SEC13L1,SEC13R,npp-20",yes,P55735
ENSG00000152700,SAR1B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SAR1B,ANDD,CMRD,GTBPB,SARA2",yes,Q9Y6B6
ENSG00000105723,GSK3A,Autophagophore initiation and elongation,"ULK1 pathway, upstream",Nutrient sensing,nan,"GSK3A,-",yes,P49840
ENSG00000172977,KAT5,Autophagophore initiation and elongation,"ULK1 pathway, upstream",Nutrient sensing,nan,"KAT5,ESA1,HTATIP,HTATIP1,PLIP,TIP,TIP60,ZC2HC5,cPLA2",yes,Q92993
ENSG00000132405,TBC1D14,Autophagophore initiation and elongation,"ULK1 pathway, upstream",Localization of ULK1 complex components,nan,"TBC1D14,-",yes,Q9P2M4
ENSG00000135413,LACRT,Autophagophore initiation and elongation,"ULK1 pathway, upstream",Modulator of ULK1 complex assembly,nan,"LACRT,-",no,Q9GZZ8
ENSG00000177169,ULK1,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"ULK1,ATG1,ATG1A,UNC51,Unc51.1,hATG1",yes,O75385
ENSG00000083290,ULK2,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"ULK2,ATG1B,Unc51.2",yes,Q8IYT8
ENSG00000140474,ULK3,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"ULK3,-",yes,Q6PHR2
ENSG00000175224,ATG13,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"ATG13,KIAA0652,PARATARG8",yes,O75143
ENSG00000023287,RB1CC1,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"RB1CC1,ATG17,CC1,FIP200,PPP1R131",yes,Q8TDY2
ENSG00000123395,ATG101,Autophagophore initiation and elongation,"ULK1 pathway, direct",ULK1 complex component,nan,"ATG101,C12orf44",yes,Q9BSB4
ENSG00000070367,EXOC5,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC5/6(6B)/7/8 subcomplex component for autophagy activation,"EXOC5,HSEC10,PRO1912,SEC10,SEC10L1,SEC10P",yes,O00471
ENSG00000138190,EXOC6,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC5/6(6B)/7/8 subcomplex component for autophagy activation,"EXOC6,EXOC6A,SEC15,SEC15L,SEC15L1,SEC15L3,Sec15p",yes,Q8TAG9
ENSG00000144036,EXOC6B,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC5/6(6B)/7/8 subcomplex component for autophagy activation,"EXOC6B,SEC15B,SEC15L2,SEMDJL3",yes,Q9Y2D4
ENSG00000182473,EXOC7,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC5/6(6B)/7/8 subcomplex component for autophagy activation,"EXOC7,2-5-3p,BLOM4,EX070,EXO70,EXOC1,Exo70p,YJL085W",yes,Q9UPT5
ENSG00000116903,EXOC8,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC5/6(6B)/7/8 subcomplex component for autophagy activation,"EXOC8,EXO84,Exo84p,SEC84",yes,Q8IYI6
ENSG00000090989,EXOC1,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC1(C1L)/C2/C3/C4 subcomplex component for autophagy suppression,"EXOC1,BM-102,SEC3,SEC3L1,SEC3P",yes,Q9NV70
ENSG00000250821,RP11-345F18.1,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC1(C1L)/C2/C3/C4 subcomplex component for autophagy suppression,"EXOC1L,-",no,A0A1B0GW35
ENSG00000112685,EXOC2,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC1(C1L)/C2/C3/C4 subcomplex component for autophagy suppression,"EXOC2,SEC5,SEC5L1,Sec5p",yes,Q96KP1
ENSG00000180104,EXOC3,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC1(C1L)/C2/C3/C4 subcomplex component for autophagy suppression,"EXOC3,SEC6,SEC6L1,Sec6p",yes,O60645
ENSG00000131558,EXOC4,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,EXOC1(C1L)/C2/C3/C4 subcomplex component for autophagy suppression,"EXOC4,SEC8,SEC8L1,Sec8p",yes,Q96A65
ENSG00000144118,RALB,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,Exocyst complex assembly modulator,"RALB,-",yes,P11234
ENSG00000118689,FOXO3,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 complex assembly,nan,"FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A",yes,O43524
ENSG00000113575,PPP2CA,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"PPP2CA,NEDLBA,PP2Ac,PP2CA,PP2Calpha,RP-C",yes,P67775
ENSG00000221914,PPP2R2A,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"PPP2R2A,B55A,B55ALPHA,PR52A,PR55A,PR55alpha",yes,P63151
ENSG00000089289,IGBP1,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"IGBP1,ALPHA-4,IBP1,alpha4",yes,P78318
ENSG00000147894,C9orf72,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"C9orf72,ALSFTD,DENND9,DENNL72,FTDALS,FTDALS1",yes,Q96LT7
ENSG00000176994,SMCR8,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"SMCR8,DENND8A",yes,Q8TEV9
ENSG00000164253,WDR41,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"WDR41,MSTP048",yes,Q9HAD4
ENSG00000181085,MAPK15,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"MAPK15,ERK7,ERK8",yes,Q8TD08
ENSG00000119787,ATL2,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"ATL2,ARL3IP2,ARL6IP2,aip-2,atlastin2",yes,Q8NHH9
ENSG00000184743,ATL3,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"ATL3,HSN1F",yes,Q6DD88
ENSG00000049759,NEDD4L,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"NEDD4L,NEDD4-2,NEDD4.2,PVNH7,RSP5,hNEDD4-2",yes,Q96PU5
ENSG00000102882,MAPK3,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"MAPK3,ERK-1,ERK1,ERT2,HS44KDAP,HUMKER1A,P44ERK1,P44MAPK,PRKM3,p44-ERK1,p44-MAPK",yes,P27361
ENSG00000036257,CUL3,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"CUL3,CUL-3,PHA2E",yes,Q13618
ENSG00000076321,KLHL20,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"KLHL20,KHLHX,KLEIP,KLHLX",yes,Q9Y2M5
ENSG00000149557,FEZ1,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"FEZ1,UNC-76",yes,Q99689
ENSG00000171055,FEZ2,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"FEZ2,HUM3CL",yes,Q9UHY8
ENSG00000153130,SCOC,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"SCOC,HRIHFB2072,SCOCO,UNC-69",yes,Q9UIL1
ENSG00000082701,GSK3B,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"GSK3B,-",yes,P49841
ENSG00000108561,C1QBP,Autophagophore initiation and elongation,"ULK1 pathway, direct",Modulator of ULK1 activity,nan,"C1QBP,COXPD33,GC1QBP,HABP1,SF2AP32,SF2p32,gC1Q-R,gC1qR,p32",yes,Q07021
ENSG00000062716,VMP1,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"VMP1,EPG3,TANGO5,TMEM49",yes,Q96GC9
ENSG00000138069,RAB1A,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"RAB1A,RAB1,YPT1",yes,P62820
ENSG00000174903,RAB1B,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"RAB1B,-",yes,Q9H0U4
ENSG00000101558,VAPA,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"VAPA,VAP-33,VAP-A,VAP33,hVAP-33",yes,Q9P0L0
ENSG00000124164,VAPB,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"VAPB,ALS8,VAMP-B,VAP-B",yes,O95292
ENSG00000104388,RAB2A,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"RAB2A,LHX,RAB2",yes,P61019
ENSG00000179331,RAB39A,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"RAB39A,RAB39",no,Q14964
ENSG00000155961,RAB39B,Autophagophore initiation and elongation,"ULK1 pathway, direct",Localization of ULK1 complex,nan,"RAB39B,BGMR,MRX72,WSMN,WSN",yes,Q96DA2
ENSG00000178607,ERN1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",ER stress signaling pathway,Modulator of BECN1 availability,"ERN1,IRE1,IRE1P,IRE1a,hIRE1p",yes,O75460
ENSG00000127191,TRAF2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",ER stress signaling pathway,Modulator of BECN1 availability,"TRAF2,MGC:45012,RNF117,TRAP,TRAP3",yes,Q12933
ENSG00000137275,RIPK1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",ER stress signaling pathway,Modulator of BECN1 availability,"RIPK1,AIEFL,IMD57,RIP,RIP-1,RIP1",yes,Q13546
ENSG00000163932,PRKCD,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Hypoxia signaling pathway,Modulator of BECN1 availability,"PRKCD,ALPS3,CVID9,MAY1,PKCD,nPKC-delta",yes,Q05655
ENSG00000162734,PEA15,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Hypoxia signaling pathway,Modulator of BECN1 availability,"PEA15,HMAT1,HUMMAT1H,MAT1,MAT1H,PEA-15,PED,PED-PEA15,PED/PEA15",yes,Q15121
ENSG00000172270,BSG,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Insulin signaling pathway,Modulator of BECN1 availability,"BSG,5F7,CD147,EMMPRIN,EMPRIN,OK,SLC7A11,TCSF",yes,P35613
ENSG00000153094,BCL2L11,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",MAPK8 signaling pathway,Modulator of BECN1 availability,"BCL2L11,BAM,BIM,BOD",yes,O43521
ENSG00000115317,HTRA2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"HTRA2,MGCA8,OMI,PARK13,PRSS25",yes,O43464
ENSG00000121481,RNF2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Modulator of class 3 PI3K complex 1 activity,Modulator of AMBRA1 by ubiquitination,"RNF2,BAP-1,BAP1,DING,HIPI3,RING1B,RING2",yes,Q99496
ENSG00000100387,RBX1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, upstream",Class 3 PI3K complex 1 signal integration,Modulator of BECN1 availability via DAPK,"RBX1,BA554C12.1,RNF75,ROC1",yes,P62877
ENSG00000078142,PIK3C3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Class 3 PI3K complex 1 component,nan,"PIK3C3,VPS34,Vps34,hVps34",yes,Q8NEB9
ENSG00000196455,PIK3R4,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Class 3 PI3K complex 1 component,nan,"PIK3R4,VPS15,p150",yes,Q99570
ENSG00000126581,BECN1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Class 3 PI3K complex 1 component,nan,"BECN1,ATG6,VPS30,beclin1",yes,Q14457
ENSG00000196289,BECN2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Class 3 PI3K complex 1 component,nan,"BECN2,BECN1L1,BECN1P1",no,A8MW95
ENSG00000126775,ATG14,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Class 3 PI3K complex 1 component,nan,"ATG14,ATG14L,BARKOR,KIAA0831",yes,Q6ZNE5
ENSG00000162889,MAPKAPK2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 phosphorylation,"MAPKAPK2,MAPKAP-K2,MK-2,MK2",yes,P49137
ENSG00000114738,MAPKAPK3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 phosphorylation,"MAPKAPK3,3PK,MAPKAP-K3,MAPKAP3,MAPKAPK-3,MDPT3,MK-3,MK3",yes,Q16644
ENSG00000101109,STK4,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 phosphorylation,"STK4,KRS2,MST1,YSK3",yes,Q13043
ENSG00000171791,BCL2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BCL2,Bcl-2,PPP1R50",yes,P10415
ENSG00000002330,BAD,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BAD,BBC2,BCL2L8",yes,Q92934
ENSG00000104081,BMF,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BMF,-",yes,Q96LC9
ENSG00000145354,CISD2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"CISD2,ERIS,Miner1,NAF-1,WFS2,ZCD2",yes,Q8N5K1
ENSG00000143384,MCL1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"MCL1,BCL2L3,EAT,MCL1-ES,MCL1L,MCL1S,Mcl-1,TM,bcl2-L-3,mcl1/EAT",yes,Q07820
ENSG00000003402,CFLAR,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"CFLAR,CASH,CASP8AP1,CLARP,Casper,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,MRIT,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,cFLIP",yes,O15519
ENSG00000189403,HMGB1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"HMGB1,HMG-1,HMG1,HMG3,SBP-1",yes,P09429
ENSG00000196730,DAPK1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"DAPK1,DAPK,ROCO3",yes,P53355
ENSG00000167657,DAPK3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"DAPK3,DLK,ZIP,ZIPK",yes,O43293
ENSG00000176171,BNIP3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BNIP3,NIP3",yes,Q12983
ENSG00000104765,BNIP3L,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BNIP3L,BNIP3a,NIX",yes,O60238
ENSG00000107643,MAPK8,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"MAPK8,JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c",yes,P45983
ENSG00000011198,ABHD5,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"ABHD5,CGI58,IECN2,NCIE2",yes,Q8WTS1
ENSG00000029363,BCLAF1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"BCLAF1,BTF,bK211L9.1",yes,Q9NYF8
ENSG00000141736,ERBB2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"ERBB2,CD340,HER-2,HER-2/neu,HER2,MLN 19,NEU,NGL,TKR1",yes,P04626
ENSG00000096060,FKBP5,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"FKBP5,AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10",yes,Q13451
ENSG00000138095,LRPPRC,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"LRPPRC,CLONE-23970,GP130,LRP130,LSFC",yes,P42704
ENSG00000141682,PMAIP1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"PMAIP1,APR,NOXA",yes,Q13794
ENSG00000143575,HAX1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"HAX1,HCLSBP1,HS1BP1,SCN3",yes,O00165
ENSG00000143514,TP53BP2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"TP53BP2,53BP2,ASPP2,BBP,P53BP2,PPP1R13A",yes,Q13625
ENSG00000146648,EGFR,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"EGFR,ERBB,ERBB1,HER1,NISBD2,PIG61,mENA",yes,P00533
ENSG00000104341,LAPTM4B,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"LAPTM4B,LAPTM4beta,LC27",yes,Q86VI4
ENSG00000055208,TAB2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"TAB2,CHTD2,MAP3K7IP2,TAB-2",yes,Q9NYJ8
ENSG00000157625,TAB3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 availability,"TAB3,MAP3K7IP3,NAP1",yes,Q8N5C8
ENSG00000181404,WASHC1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"WASHC1,FAM39E,WASH,WASH1",yes,A8K0Z3
ENSG00000167716,WDR81,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"WDR81,CAMRQ2,HYC3,PPP1R166,SORF-2",yes,Q562E7
ENSG00000105875,WDR91,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"WDR91,HSPC049,SORF-1,SORF1",yes,A4D1P6
ENSG00000066427,ATXN3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"ATXN3,AT3,ATX3,JOS,MJD,MJD1,SCA3",yes,P54252
ENSG00000011275,RNF216,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"RNF216,CAHH,TRIAD3,U7I1,UBCE7IP1,ZIN",yes,Q9NWF9
ENSG00000101557,USP14,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"USP14,TGT",yes,P54578
ENSG00000165280,VCP,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"VCP,CDC48,TERA,p97",yes,P55072
ENSG00000011465,DCN,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B",yes,P07585
ENSG00000198300,PEG3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"PEG3,PW1,ZKSCAN22,ZNF904,ZSCAN24",yes,Q9GZU2
ENSG00000128052,KDR,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 ubiquitination,"KDR,CD309,FLK1,VEGFR,VEGFR2",yes,P35968
ENSG00000105173,CCNE1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of BECN1 localization,"CCNE1,CCNE,pCCNE1",yes,P24864
ENSG00000134324,LPIN1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 activity,"LPIN1,PAP1",yes,Q14693
ENSG00000184304,PRKD1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 activity,"PRKD1,CHDED,PKC-MU,PKCM,PKD,PRKCM",yes,Q15139
ENSG00000164924,YWHAZ,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 activity,"YWHAZ,14-3-3-zeta,HEL-S-3,HEL-S-93,HEL4,KCIP-1,POPCHAS,YWHAD",yes,P63104
ENSG00000204389,HSPA1A,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 activity,"HSPA1A,HEL-S-103,HSP70-1,HSP70-1A,HSP70-2,HSP70.1,HSP70.2,HSP70I,HSP72,HSPA1",yes,P0DMV8
ENSG00000204388,HSPA1B,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 activity,"HSPA1B,HSP70-1,HSP70-1B,HSP70-2,HSP70.1,HSP70.2,HSP72,HSPA1,HSX70",yes,P0DMV9
ENSG00000055130,CUL1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 ubiquitination,"CUL1,-",yes,Q13616
ENSG00000113558,SKP1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of PIK3C3/VPS34 ubiquitination,"SKP1,EMC19,OCP-II,OCP2,SKP1A,TCEB1L,p19A",yes,P63208
ENSG00000163291,PAQR3,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,Modulator of ATG14L,"PAQR3,RKTG",yes,Q6TCH7
ENSG00000102144,PGK1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"PGK1,HEL-S-68p,MIG10,PGKA",yes,P00558
ENSG00000148572,NRBF2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"NRBF2,COPR,COPR1,COPR2,NRBF-2",yes,Q96F24
ENSG00000198668,CALM1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"CALM1,CALML2,CAM2,CAM3,CAMB,CAMC,CAMI,CAMIII,CPVT4,DD132,LQT14,PHKD,caM",yes,P0DP23
ENSG00000110497,AMBRA1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"AMBRA1,DCAF3,WDR94",yes,Q9C0C7
ENSG00000175104,TRAF6,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"TRAF6,MGC:3310,RNF85",yes,Q9Y4K3
ENSG00000139842,CUL4A,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"CUL4A,-",yes,Q13619
ENSG00000158290,CUL4B,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"CUL4B,CUL-4B,MRXHF2,MRXS15,MRXSC,SFM2",yes,Q13620
ENSG00000167986,DDB1,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"DDB1,DDBA,UV-DDB1,XAP1,XPCE,XPE,XPE-BF",yes,Q16531
ENSG00000058056,USP13,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"USP13,ISOT3,IsoT-3",yes,Q92995
ENSG00000144566,RAB5A,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"RAB5A,RAB5",yes,P20339
ENSG00000111540,RAB5B,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"RAB5B,-",yes,P61020
ENSG00000107201,DDX58,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 activity,nan,"RIGI,RIG1,DDX58,RIG-I,RLR-1,SGMRT2",yes,O95786
ENSG00000077254,USP33,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 assembly,Exocyst complex assembly modulator,"USP33,VDU1",yes,Q8TEY7
ENSG00000112079,STK38,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Modulator of class 3 PI3K complex 1 assembly,Recruits PI3K complex 1 components to exocyst complex,"STK38,NDR,NDR1",yes,Q15208
ENSG00000237693,IRGM,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Inflammation related autophagy regulation,nan,"IRGM,IFI1,IRGM1,LRG-47,LRG47",no,A1A4Y4
ENSG00000166471,TMEM41B,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Localization of class 3 PI3K complex 1,nan,"TMEM41B,-",yes,Q5BJD5
ENSG00000127774,EMC6,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Localization of class 3 PI3K complex 1,nan,"EMC6,RAB5IFL,TMEM93",yes,Q9BV81
ENSG00000179364,PACS2,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Localization of class 3 PI3K complex 1,nan,"PACS2,EIEE66,PACS-2,PACS1L",yes,Q86VP3
ENSG00000136874,STX17,Autophagophore initiation and elongation,"Class 3 PI3K complex 1, direct",Localization of class 3 PI3K complex 1,nan,"STX17,-",yes,P56962
ENSG00000137942,FNBP1L,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG3,"FNBP1L,C1orf39,TOCA1",yes,Q5T0N5
ENSG00000169398,PTK2,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG3 activity,"PTK2,FADK,FAK,FAK1,FRNK,PPP1R71,p125FAK,pp125FAK",yes,Q05397
ENSG00000204308,RNF5,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG4 activity,"RNF5,RING5,RMA1",yes,Q99942
ENSG00000197548,ATG7,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Processing of ATG5-ATG12-ATG16 complex components,"ATG7,APG7-LIKE,APG7L,GSA7",yes,O95352
ENSG00000152348,ATG10,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Processing of ATG5-ATG12-ATG16 complex components,"ATG10,APG10,APG10L,pp12616",yes,Q9H0Y0
ENSG00000101266,CSNK2A1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"CSNK2A1,CK2A1,CKII,Cka1,Cka2,OCNDS",yes,P68400
ENSG00000070770,CSNK2A2,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"CSNK2A2,CK2A2,CK2alpha',CSNK2A1",yes,P19784
ENSG00000204435,CSNK2B,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"CSNK2B,CK2B,CK2N,CSK2B,Ckb1,Ckb2,G5A,POBINDS",yes,P67870
ENSG00000150907,FOXO1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"FOXO1,FKH1,FKHR,FOXO1A",yes,Q12778
ENSG00000068903,SIRT2,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"SIRT2,SIR2,SIR2L,SIR2L2",yes,Q8IXJ6
ENSG00000109083,IFT20,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"IFT20,-",yes,Q8IY31
ENSG00000032742,IFT88,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"IFT88,D13S1056E,DAF19,TG737,TTC10,hTg737",yes,Q13099
ENSG00000152661,GJA1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"GJA1,AVSD3,CMDR,CX43,EKVP,EKVP3,GJAL,HLHS1,HSS,ODDD,PPKCA",yes,P17302
ENSG00000096717,SIRT1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"SIRT1,SIR2,SIR2L1,SIR2alpha",yes,Q96EB6
ENSG00000124422,USP22,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"USP22,USP3L",yes,Q9UPT9
ENSG00000104881,PPP1R13L,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"PPP1R13L,IASPP,NKIP1,RAI,RAI4",yes,Q8WUF5
ENSG00000089685,BIRC5,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex assembly,"BIRC5,API4,EPR-1",yes,O15392
ENSG00000204628,RACK1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Modulation of ATG5-ATG12-ATG16 complex activity,"RACK1,GNB2L1,Gnb2-rs1,H12.3,HLC-7,PIG21",yes,P63244
ENSG00000115363,EVA1A,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"EVA1A,FAM176A,TMEM166",yes,Q9H8M9
ENSG00000164841,TMEM74,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"TMEM74,NET36",no,Q96NL1
ENSG00000068354,TBC1D25,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"TBC1D25,MG81,OATL1",yes,Q3MII6
ENSG00000172007,RAB33B,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"RAB33B,SMC2",yes,Q9H082
ENSG00000106100,NOD1,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"NOD1,CARD4,CLR7.1,NLRC1",yes,Q9Y239
ENSG00000167207,NOD2,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"NOD2,ACUG,BLAU,BLAUS,CARD15,CD,CLR16.3,IBD1,NLRC2,NOD2B,PSORAS1,YAOS",yes,Q9HC29
ENSG00000134242,PTPN22,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"PTPN22,LYP,LYP1,LYP2,PEP,PTPN22.5,PTPN22.6,PTPN8",yes,Q9Y2R2
ENSG00000116209,TMEM59,Autophagophore initiation and elongation,"ATG8 homolog processing, upstream",Preparation of ATG8 homologs for lipidation,Localization of ATG5-ATG12-ATG16 complex,"TMEM59,C1orf8,DCF1,HSPC001,PRO195,UNQ169",yes,Q9BXS4
ENSG00000140941,MAP1LC3B,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,ATG8 homolog,"MAP1LC3B,ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a",yes,Q9GZQ8
ENSG00000170296,GABARAP,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,ATG8 homolog,"GABARAP,ATG8A,GABARAP-a,MM46",yes,O95166
ENSG00000139112,GABARAPL1,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,ATG8 homolog,"GABARAPL1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1",yes,Q9H0R8
ENSG00000145782,ATG12,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE,"ATG12,APG12,APG12L,FBR93,HAPG12",yes,O94817
ENSG00000057663,ATG5,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE,"ATG5,APG5,APG5-LIKE,APG5L,ASP,SCAR25,hAPG5",yes,Q9H1Y0
ENSG00000085978,ATG16L1,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE,"ATG16L1,APG16L,ATG16A,ATG16L,IBD10,WDR30",yes,Q676U5
ENSG00000168010,ATG16L2,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE,"ATG16L2,ATG16B,WDR80",yes,Q8NAA4
ENSG00000101844,ATG4A,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Protease that removes C-terminal Arg from ATG8,"ATG4A,APG4A,AUTL2",yes,Q8WYN0
ENSG00000168397,ATG4B,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Protease that removes C-terminal Arg from ATG8,"ATG4B,APG4B,AUTL1",yes,Q9Y4P1
ENSG00000125703,ATG4C,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Protease that removes C-terminal Arg from ATG8,"ATG4C,APG4-C,APG4C,AUTL1,AUTL3",yes,Q96DT6
ENSG00000130734,ATG4D,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,Protease that removes C-terminal Arg from ATG8,"ATG4D,APG4-D,APG4D,AUTL4",yes,Q86TL0
ENSG00000144848,ATG3,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Preparation of ATG8 homologs for lipidation,E2-like enzyme conjugated to ATG8 before transfer to PE,"ATG3,APG3,APG3-LIKE,APG3L,PC3-96",yes,Q9NT62
ENSG00000154277,UCHL1,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Deubiquitination of ATG8 homologs,nan,"UCHL1,HEL-117,HEL-S-53,NDGOA,PARK5,PGP 9.5,PGP9.5,PGP95,SPG79,Uch-L1",yes,P09936
ENSG00000103194,USP10,Autophagophore initiation and elongation,"ATG8 homolog processing, direct",Deubiquitination of ATG8 homologs,nan,"USP10,UBPO",yes,Q14694
ENSG00000170043,TRAPPC1,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC1,BET5,MUM2",yes,Q9Y5R8
ENSG00000054116,TRAPPC3,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC3,BET3",yes,O43617
ENSG00000196655,TRAPPC4,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC4,CGI-104,HSPC172,NEDESBA,PTD009,SBDN,SYNBINDIN,TRS23",yes,Q9Y296
ENSG00000181029,TRAPPC5,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC5,TRS31",yes,Q8IUR0
ENSG00000153339,TRAPPC8,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC8,GSG1,HsT2706,KIAA1012,TRS85",yes,Q9Y2L5
ENSG00000168538,TRAPPC11,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC11,C4orf41,FOIGR,GRY,LGMD2S,LGMDR18",yes,Q7Z392
ENSG00000171853,TRAPPC12,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC12,CGI-87,PEBAS,TTC-15,TTC15",yes,Q8WVT3
ENSG00000113597,TRAPPC13,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,TRAPP complex component,nan,"TRAPPC13,C5orf44,SHLD3",yes,A5PLN9
ENSG00000161011,SQSTM1,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B",yes,Q13501
ENSG00000078804,TP53INP2,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"TP53INP2,C20orf110,DOR,PIG-U,PIGU,PINH,dJ1181N3.1",yes,Q8IXH6
ENSG00000167110,GOLGA2,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"GOLGA2,GM130",yes,Q08379
ENSG00000095787,WAC,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"WAC,BM-016,DESSH,PRO1741,Wwp4",yes,Q9BTA9
ENSG00000141376,BCAS3,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"BCAS3,GAOB1,MAAB",yes,Q9H6U6
ENSG00000125149,C16orf70,Autophagophore initiation and elongation,Autophagy component recruitment to autophagophore,nan,nan,"PHAF1,LIN10,lin-10,C16orf6,C16orf70",yes,Q9BSU1
ENSG00000110046,ATG2A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"ATG2A,-",yes,Q2TAZ0
ENSG00000066739,ATG2B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"ATG2B,C14orf103",yes,Q96BY7
ENSG00000070540,WIPI1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"WIPI1,ATG18,ATG18A,WIPI49",yes,Q5MNZ9
ENSG00000157954,WIPI2,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"WIPI2,ATG18B,Atg21,CGI-50,IDDSSA,WIPI-2",yes,Q9Y4P8
ENSG00000141580,WDR45B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"WDR45B,NEDSBAS,WDR45L,WIPI-3,WIPI3",yes,Q5MNZ6
ENSG00000196998,WDR45,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex component,nan,"WDR45,JM5,NBIA4,NBIA5,WDRX1,WIPI-4,WIPI4",yes,Q9Y484
ENSG00000134072,CAMK1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG2-WIPI complex modulator,nan,"CAMK1,CAMKI",yes,Q14012
ENSG00000198925,ATG9A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 homolog,nan,"ATG9A,APG9L1,MGD3208,mATG9",yes,Q7Z3C6
ENSG00000181652,ATG9B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 homolog,nan,"ATG9B,APG9L2,NOS3AS,SONE",yes,Q674R7
ENSG00000112115,IL17A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"IL17A,CTLA-8,CTLA8,IL-17,IL-17A,IL17",no,Q16552
ENSG00000118785,SPP1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"SPP1,BNSP,BSPI,ETA-1,OPN",yes,P10451
ENSG00000112062,MAPK14,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"MAPK14,CSBP,CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA",yes,Q16539
ENSG00000100292,HMOX1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"HMOX1,HMOX1D,HO-1,HSP32,bK286B10",yes,P09601
ENSG00000136869,TLR4,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"TLR4,ARMD10,CD284,TLR-4,TOLL",yes,O00206
ENSG00000127666,TICAM1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Signaling upstream of ATG9 localization,MAPK14 signaling,"TICAM1,IIAE6,MyD88-3,PRVTIRB,TICAM-1,TRIF",yes,Q8IUC6
ENSG00000131374,TBC1D5,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 localization,nan,"TBC1D5,-",yes,Q92609
ENSG00000102710,SUPT20H,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 localization,nan,"SUPT20H,C13,C13orf19,FAM48A,FP757,P38IP,SPT20",yes,Q8NEM7
ENSG00000132254,ARFIP2,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 localization,nan,"ARFIP2,POR1",yes,P53365
ENSG00000114520,SNX4,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 localization,nan,"SNX4,ATG24B",yes,O95219
ENSG00000162627,SNX7,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG9 localization,nan,"SNX7,-",yes,Q9UNH6
ENSG00000124333,VAMP7,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"VAMP7,SYBL1,TI-VAMP,TIVAMP,VAMP-7",yes,P51809
ENSG00000079950,STX7,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"STX7,-",yes,O15400
ENSG00000170310,STX8,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"STX8,CARB",yes,Q9UNK0
ENSG00000100568,VTI1B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"VTI1B,VTI1,VTI1-LIKE,VTI1L,VTI2,v-SNARE,vti1-rp1",yes,Q9UEU0
ENSG00000049245,VAMP3,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"VAMP3,CEB",yes,Q15836
ENSG00000220205,VAMP2,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex,"VAMP2,NEDHAHM,SYB2,VAMP-2",yes,P63027
ENSG00000073921,PICALM,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ATG16L1-positive plasma membrane input,Autophagophore-vesicle SNARE complex regulator,"PICALM,CALM,CLTH,LAP",yes,Q13492
ENSG00000138674,SEC31A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC31A,ABP125,ABP130,HSPC275,HSPC334,NEDSOSB,SEC31L1",yes,O94979
ENSG00000075826,SEC31B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC31B,SEC31B-1,SEC31L2",yes,Q9NQW1
ENSG00000100934,SEC23A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC23A,CLSD,hSec23A",yes,Q15436
ENSG00000101310,SEC23B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC23B,CDA-II,CDAII,CDAN2,CWS7,HEMPAS,hSec23B",yes,Q15437
ENSG00000107651,SEC23IP,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC23IP,MSTP053,P125,P125A",yes,Q9Y6Y8
ENSG00000113615,SEC24A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC24A,-",yes,O95486
ENSG00000138802,SEC24B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC24B,SEC24",yes,O95487
ENSG00000176986,SEC24C,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC24C,-",yes,P53992
ENSG00000150961,SEC24D,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SEC24D,CLCRP2",yes,O94855
ENSG00000079332,SAR1A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component,"SAR1A,SAR1,SARA1,Sara,masra2",yes,Q9NR31
ENSG00000196663,TECPR2,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component localization,"TECPR2,KIAA0329,SPG49",yes,O15040
ENSG00000159069,FBXW5,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component regulator,"FBXW5,Fbw5",yes,Q969U6
ENSG00000141551,CSNK1D,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,COPII vesicle component regulator,"CSNK1D,ASPS,CKI-delta,CKId,CKIdelta,FASPS2,HCKID",yes,P48730
ENSG00000118508,RAB32,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,ER membrane input,nan,"RAB32,-",yes,Q13637
ENSG00000168118,RAB4A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Mitochondrial membrane input,nan,"RAB4A,HRES-1,HRES-1/RAB4,HRES1,RAB4",yes,P20338
ENSG00000167578,RAB4B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Mitochondrial membrane input,nan,"RAB4B,-",yes,P61018
ENSG00000123595,RAB9A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Golgi membrane input,nan,"RAB9A,RAB9",yes,P51151
ENSG00000123570,RAB9B,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Golgi membrane input,nan,"RAB9B,RAB9L,Rab-9L",yes,Q9NP90
ENSG00000103769,RAB11A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Endosomal membrane input,nan,"RAB11A,YL8",yes,P62491
ENSG00000206418,RAB12,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Endosomal membrane input,nan,"RAB12,-",yes,Q6IQ22
ENSG00000178996,SNX18,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Endosomal membrane input,nan,"SNX18,SH3PX2,SH3PXD3B,SNAG1",yes,Q96RF0
ENSG00000079805,DNM2,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Endosomal membrane input,nan,"DNM2,CMT2M,CMTDI1,CMTDIB,DI-CMTB,DYN2,DYNII,LCCS5",yes,P50570
ENSG00000118960,HS1BP3,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Endosomal membrane input,nan,"HS1BP3,ETM2,HS1-BP3",yes,Q53T59
ENSG00000100330,MTMR3,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Regulation of PI3P levels,nan,"MTMR3,FYVE-DSP1,ZFYVE10",yes,Q13615
ENSG00000108389,MTMR4,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Regulation of PI3P levels,nan,"MTMR4,FYVE-DSP2,ZFYVE11",yes,Q9NYA4
ENSG00000102043,MTMR8,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Regulation of PI3P levels,nan,"MTMR8,-",no,Q96EF0
ENSG00000104643,MTMR9,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Regulation of PI3P levels,nan,"MTMR9,C8orf9,LIP-STYX,MTMR8",yes,Q96QG7
ENSG00000163719,MTMR14,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,Regulation of PI3P levels,nan,"MTMR14,C3orf29",yes,Q8NCE2
ENSG00000165861,ZFYVE1,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,PI3P sequestration,nan,"ZFYVE1,DFCP1,PPP1R172,SR3,TAFF1,ZNFN2A1",yes,Q9HBF4
ENSG00000143393,PI4KB,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,PI4P production,nan,"PI4KB,NPIK,PI4K-BETA,PI4K92,PI4KBETA,PI4KIII,PI4KIIIBETA,PIK4CB",yes,Q9UBF8
ENSG00000184584,TMEM173,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,nan,nan,"STING1,ERIS,MITA,MPYS,NET23,SAVI,STING,STING-beta,TMEM173,hMITA,hSTING",yes,Q86WV6
ENSG00000089351,GRAMD1A,Autophagophore initiation and elongation,Regulation of autophagophore membrane composition,nan,nan,"GRAMD1A,KIAA1533",yes,Q96CP6
ENSG00000156232,WHAMM,Autophagophore initiation and elongation,Regulation of autophagophore morphology,nan,nan,"WHAMM,WHAMM1,WHDC1",yes,Q8TF30
ENSG00000152409,JMY,Autophagophore initiation and elongation,Regulation of autophagophore morphology,nan,nan,"JMY,WHAMM2,WHDC1L3",yes,Q8N9B5
ENSG00000077549,CAPZB,Autophagophore initiation and elongation,Regulation of autophagophore morphology,nan,nan,"CAPZB,CAPB,CAPPB,CAPZ",yes,P47756
ENSG00000188906,LRRK2,Autophagophore initiation and elongation,"LRRK2 pathway, direct",LRRK2 itself,nan,"LRRK2,AURA17,DARDARIN,PARK8,RIPK7,ROCO2",yes,Q5S007
ENSG00000186815,TPCN1,Autophagophore initiation and elongation,"LRRK2 pathway, direct",Modulator of LRRK2 activity,nan,"TPCN1,TPC1",yes,Q9ULQ1
ENSG00000162341,TPCN2,Autophagophore initiation and elongation,"LRRK2 pathway, direct",Modulator of LRRK2 activity,nan,"TPCN2,SHEP10,TPC2",yes,Q8NHX9
ENSG00000065675,PRKCQ,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"PRKCQ,PRKCT,nPKC-theta",yes,Q04759
ENSG00000189067,LITAF,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"LITAF,PIG7,SIMPLE,TP53I7",yes,Q99732
ENSG00000140464,PML,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"PML,MYL,PP8675,RNF71,TRIM19",yes,P29590
ENSG00000175354,PTPN2,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"PTPN2,PTN2,PTPT,TC-PTP,TCELLPTP,TCPTP",yes,P17706
ENSG00000038532,CLEC16A,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"CLEC16A,Gop-1,KIAA0350",yes,Q2KHT3
ENSG00000149547,EI24,Autophagophore initiation and elongation,Specific function in autophagophore initiation and elongation unknown,nan,nan,"EI24,EPG4,PIG8,TP53I8",yes,O14681
ENSG00000149557,FEZ1,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"FEZ1,UNC-76",yes,Q99689
ENSG00000171055,FEZ2,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"FEZ2,HUM3CL",yes,Q9UHY8
ENSG00000153130,SCOC,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"SCOC,HRIHFB2072,SCOCO,UNC-69",yes,Q9UIL1
ENSG00000101558,VAPA,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Recruitment of autophagosome to vicinity of ER,nan,"VAPA,VAP-33,VAP-A,VAP33,hVAP-33",yes,Q9P0L0
ENSG00000104388,RAB2A,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,"Bridges STX17, RUBCNL and HOPS complex","RAB2A,LHX,RAB2",yes,P61019
ENSG00000078142,PIK3C3,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"PIK3C3,VPS34,Vps34,hVps34",yes,Q8NEB9
ENSG00000196455,PIK3R4,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"PIK3R4,VPS15,p150",yes,Q99570
ENSG00000126581,BECN1,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"BECN1,ATG6,VPS30,beclin1",yes,Q14457
ENSG00000126775,ATG14,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"ATG14,ATG14L,BARKOR,KIAA0831",yes,Q6ZNE5
ENSG00000101109,STK4,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog phosphorylation,"STK4,KRS2,MST1,YSK3",yes,Q13043
ENSG00000165280,VCP,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"VCP,CDC48,TERA,p97",yes,P55072
ENSG00000136874,STX17,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"STX17,-",yes,P56962
ENSG00000068354,TBC1D25,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"TBC1D25,MG81,OATL1",yes,Q3MII6
ENSG00000172007,RAB33B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"RAB33B,SMC2",yes,Q9H082
ENSG00000140941,MAP1LC3B,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,ATG8 homolog,"MAP1LC3B,ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a",yes,Q9GZQ8
ENSG00000170296,GABARAP,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog,"GABARAP,ATG8A,GABARAP-a,MM46",yes,O95166
ENSG00000139112,GABARAPL1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog,"GABARAPL1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1",yes,Q9H0R8
ENSG00000145782,ATG12,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"ATG12,APG12,APG12L,FBR93,HAPG12",yes,O94817
ENSG00000057663,ATG5,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"ATG5,APG5,APG5-LIKE,APG5L,ASP,SCAR25,hAPG5",yes,Q9H1Y0
ENSG00000101844,ATG4A,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,ATG8 homolog de-lipidation,Releases ATG8 homologs from maturing autophagosome,"ATG4A,APG4A,AUTL2",yes,Q8WYN0
ENSG00000168397,ATG4B,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,ATG8 homolog de-lipidation,Releases ATG8 homologs from maturing autophagosome,"ATG4B,APG4B,AUTL1",yes,Q9Y4P1
ENSG00000125703,ATG4C,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,ATG8 homolog de-lipidation,Releases ATG8 homologs from maturing autophagosome,"ATG4C,APG4-C,APG4C,AUTL1,AUTL3",yes,Q96DT6
ENSG00000130734,ATG4D,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,ATG8 homolog de-lipidation,Releases ATG8 homologs from maturing autophagosome,"ATG4D,APG4-D,APG4D,AUTL4",yes,Q86TL0
ENSG00000124333,VAMP7,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"VAMP7,SYBL1,TI-VAMP,TIVAMP,VAMP-7",yes,P51809
ENSG00000079950,STX7,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"STX7,-",yes,O15400
ENSG00000100568,VTI1B,Autophagosome closure maturation and lysosome fusion,Autophagosome-endosome docking,Lysosome-endosome SNARE complex,nan,"VTI1B,VTI1,VTI1-LIKE,VTI1L,VTI2,v-SNARE,vti1-rp1",yes,Q9UEU0
ENSG00000049245,VAMP3,Autophagosome closure maturation and lysosome fusion,Autophagosome-endosome docking,Lysosome-endosome SNARE complex,nan,"VAMP3,CEB",yes,Q15836
ENSG00000141551,CSNK1D,Autophagosome closure maturation and lysosome fusion,Sealing of autophagophore membrane,Specific function in sealing of autophagophore membrane unknown,nan,"CSNK1D,ASPS,CKI-delta,CKId,CKIdelta,FASPS2,HCKID",yes,P48730
ENSG00000188906,LRRK2,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"LRRK2,AURA17,DARDARIN,PARK8,RIPK7,ROCO2",yes,Q5S007
ENSG00000075785,RAB7A,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"RAB7A,CMT2B,PRO2706,RAB7",yes,P51149
ENSG00000276600,RAB7B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"RAB7B,RAB7",yes,Q96AH8
ENSG00000136436,CALCOCO2,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along actin,nan,"CALCOCO2,NDP52",yes,Q13137
ENSG00000106052,TAX1BP1,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along actin,nan,"TAX1BP1,CALCOCO3,T6BP,TXBP151",yes,Q86VP1
ENSG00000101460,MAP1LC3A,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog,"MAP1LC3A,ATG8E,LC3,LC3A,MAP1ALC3,MAP1BLC3",yes,Q9H492
ENSG00000197769,MAP1LC3C,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog,"MAP1LC3C,ATG8J,LC3C",yes,Q9BXW4
ENSG00000034713,GABARAPL2,Autophagosome closure maturation and lysosome fusion,Sealing of autophagophore membrane,Specific function in sealing of autophagophore membrane unknown,ATG8 homolog,"GABARAPL2,ATG8,ATG8C,GATE-16,GATE16,GEF-2,GEF2",yes,P60520
ENSG00000074319,TSG101,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"TSG101,TSG10,VPS23",yes,Q99816
ENSG00000160948,VPS28,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"VPS28,-",yes,Q9UK41
ENSG00000155975,VPS37A,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"VPS37A,HCRP1,PQBP2,SPG53",yes,Q8NEZ2
ENSG00000139722,VPS37B,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"VPS37B,-",yes,Q9H9H4
ENSG00000167987,VPS37C,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"VPS37C,-",yes,A5D8V6
ENSG00000176428,VPS37D,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"VPS37D,WBSCR24",yes,Q86XT2
ENSG00000141971,MVB12A,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"MVB12A,CFBP,FAM125A",yes,Q96EY5
ENSG00000196814,MVB12B,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"MVB12B,C9orf28,FAM125B",yes,Q9H7P6
ENSG00000165006,UBAP1,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"UBAP1,NAG20,SPG80,UAP,UBAP,UBAP-1",yes,Q9NZ09
ENSG00000219545,UMAD1,ESCRT,Sealing of autophagophore membrane,ESCRT-I complex component,nan,"UMAD1,RPA3-AS1,RPA3OS",yes,C9J7I0
ENSG00000131165,CHMP1A,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP1A,CHMP1,PCH8,PCOLN3,PRSM1,VPS46-1,VPS46A",yes,Q9HD42
ENSG00000255112,CHMP1B,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP1B,C10orf2,C18-ORF2,C18orf2,CHMP1.5,Vps46-2,Vps46B,hVps46-2",yes,Q7LBR1
ENSG00000130724,CHMP2A,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP2A,BC-2,BC2,CHMP2,VPS2,VPS2A",yes,O43633
ENSG00000083937,CHMP2B,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP2B,ALS17,CHMP2.5,DMT1,VPS2-2,VPS2B",yes,Q9UQN3
ENSG00000115561,CHMP3,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP3,CGI-149,NEDF,VPS24",yes,Q9Y3E7
ENSG00000254505,CHMP4A,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP4A,C14orf123,CHMP4,CHMP4B,HSPC134,SHAX2,SNF7,SNF7-1,VPS32-1,VPS32A",yes,Q9BY43
ENSG00000101421,CHMP4B,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP4B,C20orf178,CHMP4A,CTPP3,CTRCT31,SNF7,SNF7-2,Shax1,VPS32B,Vps32-2,dJ553F4.4",yes,Q9H444
ENSG00000164695,CHMP4C,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP4C,SNF7-3,Shax3,VPS32C",yes,Q96CF2
ENSG00000086065,CHMP5,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP5,C9orf83,CGI-34,HSPC177,PNAS-2,SNF7DC2,Vps60",yes,Q9NZZ3
ENSG00000176108,CHMP6,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP6,VPS20",yes,Q96FZ7
ENSG00000147457,CHMP7,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex component,nan,"CHMP7,-",yes,Q8WUX9
ENSG00000132612,VPS4A,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex activity modulator,nan,"VPS4A,SKD1,SKD1A,SKD2,VPS4,VPS4-1",yes,Q9UN37
ENSG00000119541,VPS4B,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex activity modulator,nan,"VPS4B,MIG1,SKD1,SKD1B,VPS4-2",yes,O75351
ENSG00000117758,STX12,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex activity modulator,nan,"STX12,STX13,STX14",yes,Q86Y82
ENSG00000151532,VTI1A,ESCRT,Sealing of autophagophore membrane,ESCRT-III complex activity modulator,nan,"VTI1A,MMDS3,MVti1,VTI1RP2,Vti1-rp2",yes,Q96AJ9
ENSG00000170248,PDCD6IP,ESCRT,Sealing of autophagophore membrane,Localization of the ESCRT-III complex,nan,"PDCD6IP,AIP1,ALIX,DRIP4,HP95",yes,Q8WUM4
ENSG00000167705,RILP,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"RILP,PP10141",yes,Q96NA2
ENSG00000121653,MAPK8IP1,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"MAPK8IP1,IB1,JIP-1,JIP1,PRKM8IP",yes,Q9UQF2
ENSG00000163820,FYCO1,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"FYCO1,CATC2,CTRCT18,RUFY3,ZFYVE7",yes,Q9BQS8
ENSG00000143862,ARL8A,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"ARL8A,ARL10B,GIE2",yes,Q96BM9
ENSG00000134108,ARL8B,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"ARL8B,ARL10C,Gie1",yes,Q9NVJ2
ENSG00000018189,RUFY3,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"RUFY3,RIPX,SINGAR1,ZFYVE30",yes,Q7L099
ENSG00000188282,RUFY4,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along microtubules,nan,"RUFY4,ZFYVE31",no,Q6ZNE9
ENSG00000196586,MYO6,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along actin,nan,"MYO6,DFNA22,DFNB37",yes,Q9UM54
ENSG00000100284,TOM1,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Movement of autophagosomes along actin,nan,"TOM1,IMD85",yes,O60784
ENSG00000197386,HTT,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Retrograde transport along axons,nan,"HTT,HD,IT15,LOMARS",yes,P42858
ENSG00000173805,HAP1,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Retrograde transport along axons,nan,"HAP1,HAP2,HIP5,HLP,hHLP1",yes,P54257
ENSG00000141447,OSBPL1A,Autophagosome closure maturation and lysosome fusion,Localization of the autophagosome,Recruitment of autophagosome to vicinity of ER,nan,"OSBPL1A,ORP-1,ORP1,OSBPL1B",yes,Q9BXW6
ENSG00000115020,PIKFYVE,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,PIKFYVE complex component,nan,"PIKFYVE,CFD,FAB1,HEL37,PIP5K,PIP5K3,ZFYVE29",yes,Q9Y2I7
ENSG00000103043,VAC14,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,PIKFYVE complex component,nan,"VAC14,ArPIKfyve,TAX1BP2,TRX",yes,Q08AM6
ENSG00000112367,FIG4,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,PIKFYVE complex component,nan,"FIG4,ALS11,BTOP,CMT4J,KIAA0274,SAC3,YVS,dJ249I4.1",yes,Q92562
ENSG00000155252,PI4K2A,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,nan,nan,"PI4K2A,PI4KII,PIK42A",yes,Q9BTU6
ENSG00000148384,INPP5E,Autophagosome closure maturation and lysosome fusion,Regulation of autophagosome membrane composition,nan,nan,"INPP5E,CORS1,CPD4,JBTS1,MORMS,PPI5PIV,pharbin",yes,Q9NRR6
ENSG00000198382,UVRAG,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"UVRAG,DHTX,VPS38,p63",yes,Q9P2Y5
ENSG00000097033,SH3GLB1,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"SH3GLB1,Bif-1,CGI-61,PPP1R70,dJ612B15.2",yes,Q9Y371
ENSG00000145016,RUBCN,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"RUBCN,KIAA0226,RUBICON,SCAR15",yes,Q92622
ENSG00000102445,RUBCNL,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Class 3 PI3K complex 2 component,nan,"RUBCNL,C13orf18,KIAA0226L,PACER",yes,Q9H714
ENSG00000072121,ZFYVE26,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"ZFYVE26,FYVE-CENT,SPG15",yes,Q68DK2
ENSG00000198742,SMURF1,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"SMURF1,-",yes,Q9HCE7
ENSG00000142149,HUNK,Autophagosome closure maturation and lysosome fusion,"Class 3 PI3K complex 2, direct",Modulator of class 3 PI3K complex 2 activity,nan,"HUNK,-",no,P57058
ENSG00000135823,STX6,Autophagosome closure maturation and lysosome fusion,Autophagosome-endosome docking,Lysosome-endosome SNARE complex,nan,"STX6,-",yes,O43752
ENSG00000117280,RAB29,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"RAB29,RAB7L,RAB7L1",yes,O14966
ENSG00000164077,MON1A,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"MON1A,SAND1",yes,Q86VX9
ENSG00000103111,MON1B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"MON1B,HSRG1,SAND2,SRG1",yes,Q7L1V2
ENSG00000122674,CCZ1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"CCZ1,C7orf28A,CCZ1A,CGI-43,H_DJ1163J12.2",yes,P86791
ENSG00000146574,CCZ1B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"CCZ1B,C7orf28A,C7orf28B,CCZ1,H_NH0577018.2",yes,P86790
ENSG00000141452,C18orf8,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"RMC1,C18orf8,HsT2591,MIC1,Mic-1,WDR98",yes,Q96DM3
ENSG00000154237,LRRK1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"LRRK1,RIPK6,Roco1",yes,Q38SD2
ENSG00000095383,TBC1D2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Tethering factor recruitment,nan,"TBC1D2,PARIS-1,PARIS1,TBC1D2A",yes,Q9BYX2
ENSG00000166128,RAB8B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"RAB8B,-",yes,Q92930
ENSG00000099940,SNAP29,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"SNAP29,CEDNIK,SNAP-29",yes,O95721
ENSG00000106636,YKT6,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"YKT6,-",yes,O15498
ENSG00000118640,VAMP8,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex,nan,"VAMP8,EDB,VAMP-8",yes,Q9BV40
ENSG00000115760,BIRC6,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"BIRC6,APOLLON,BRUCE",yes,Q9NR09
ENSG00000080371,RAB21,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"RAB21,-",yes,Q9UL25
ENSG00000133812,SBF2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"SBF2,CMT4B2,DENND7B,MTMR13",yes,Q86WG5
ENSG00000152223,EPG5,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"EPG5,HEEW1,KIAA1632,VICIS",yes,Q9HCE0
ENSG00000147162,OGT,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"OGT,HINCUT-1,HRNT1,MRX106,O-GLCNAC,OGT1",yes,O15294
ENSG00000141458,NPC1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome SNARE complex regulator,nan,"NPC1,NPC,POGZ,SLC65A1",yes,O15118
ENSG00000135441,BLOC1S1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BLOC1S1,BLOS1,BORCS1,GCN5L1,MICoA,RT14",yes,P78537
ENSG00000196072,BLOC1S2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BLOC1S2,BLOS2,BORCS2,CEAP,CEAP11",yes,Q6QNY1
ENSG00000143553,SNAPIN,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"SNAPIN,BLOC1S7,BLOS7,BORCS3,SNAPAP",yes,O95295
ENSG00000105700,KXD1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"KXD1,BORCS4,C10orf50,C19orf50,KXDL,MST096,MSTP096",yes,Q9BQD3
ENSG00000165714,BORCS5,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BORCS5,LOH12CR1,LOH1CR12",yes,Q969J3
ENSG00000196544,BORCS6,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BORCS6,C17orf59,PRO2472",yes,Q96GS4
ENSG00000166275,BORCS7,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BORCS7,C10orf32",yes,Q96B45
ENSG00000254901,BORCS8,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,BORC complex component,nan,"BORCS8,MEF2BNB",yes,Q96FH0
ENSG00000160695,VPS11,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS11,END1,HLD12,PEP5,RNF108,hVPS11",yes,Q9H270
ENSG00000215305,VPS16,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS16,hVPS16",yes,Q9H269
ENSG00000104142,VPS18,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS18,PEP3",yes,Q9P253
ENSG00000139719,VPS33A,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS33A,MPSPS",yes,Q96AX1
ENSG00000166887,VPS39,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS39,TLP,VAM6,hVam6p",yes,Q96JC1
ENSG00000006715,VPS41,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS complex component,nan,"VPS41,HVPS41,HVSP41,hVps41p",yes,P49754
ENSG00000054523,KIF1B,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS-BORC interaction mediator,nan,"KIF1B,CMT2,CMT2A,CMT2A1,HMSNII,KLP,NBLST1",yes,O60333
ENSG00000116786,PLEKHM2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,HOPS-BORC interaction mediator,nan,"PLEKHM2,SKIP",yes,Q8IWE5
ENSG00000104375,STK3,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,ATG8 homolog phosphorylation,"STK3,KRS1,MST2",yes,Q13188
ENSG00000225190,PLEKHM1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Recruitment of HOPS complex to autophagosome,Bridges ATG8 and HOPS complex,"PLEKHM1,AP162,B2,OPTA3,OPTB6",yes,Q9Y4G2
ENSG00000197122,SRC,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,ATG8-LAMP1 interaction modulator,nan,"SRC,ASV,SRC1,THC6,c-SRC,p60-Src",yes,P12931
ENSG00000115806,GORASP2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,ATG8-LAMP2 interaction modulator,nan,"GORASP2,GOLPH6,GRASP55,GRS2,p59",yes,Q9H8Y8
ENSG00000094631,HDAC6,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"HDAC6,CPBHM,HD6,JM21,PPP1R90",yes,Q9UBN7
ENSG00000085733,CTTN,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"CTTN,EMS1",yes,Q14247
ENSG00000205356,TECPR1,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"TECPR1,-",yes,Q7Z6L1
ENSG00000188603,CLN3,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"CLN3,BTN1,BTS,JNCL",yes,Q13286
ENSG00000005893,LAMP2,Autophagosome closure maturation and lysosome fusion,Autophagosome-lysosome docking,Lysosome-autophagosome interaction modulator,nan,"LAMP2,CD107b,DND,LAMP-2,LAMPB,LGP-96,LGP110",yes,P13473
ENSG00000170759,KIF5B,Autophagosome closure maturation and lysosome fusion,Localization of the lysosome,nan,nan,"KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC",yes,P33176
ENSG00000090674,MCOLN1,Autophagosome closure maturation and lysosome fusion,Ca2+ efflux,nan,nan,"MCOLN1,MG-2,ML1,ML4,MLIV,MST080,MSTP080,TRP-ML1,TRPM-L1,TRPML1",yes,Q9GZU1
ENSG00000055732,MCOLN3,Autophagosome closure maturation and lysosome fusion,Ca2+ efflux,nan,nan,"MCOLN3,TRP-ML3,TRPML3",yes,Q8TDD5
ENSG00000169228,RAB24,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"RAB24,-",yes,Q969Q5
ENSG00000100813,ACIN1,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"ACIN1,ACINUS,ACN,fSAP152",yes,Q9UKV3
ENSG00000164885,CDK5,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"CDK5,LIS7,PSSALRE",yes,Q00535
ENSG00000176749,CDK5R1,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"CDK5R1,CDK5P35,CDK5R,NCK5A,p23,p25,p35,p35nck5a",yes,Q15078
ENSG00000136048,DRAM1,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"DRAM1,DRAM",yes,Q8N682
ENSG00000156171,DRAM2,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"DRAM2,CORD21,PRO180,TMEM77,WWFQ154",yes,Q6UX65
ENSG00000180061,TMEM150B,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"TMEM150B,DRAM3,TMEM224,TTN2",yes,A6NC51
ENSG00000170145,SIK2,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"SIK2,LOH11CR1I,QIK,SIK-2,SNF1LK2",yes,Q9H0K1
ENSG00000135317,SNX14,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"SNX14,RGS-PX2,SCAR20",yes,Q9Y5W7
ENSG00000116260,QSOX1,Autophagosome closure maturation and lysosome fusion,Specific function in autophagosome maturation and lysosome fusion unknown,nan,nan,"QSOX1,Q6,QSCN6",yes,O00391
ENSG00000136100,VPS36,ESCRT,none,ESCRT,none,none,yes,none
ENSG00000141510,TP53,Autophagy gene expression,TP53 transcriptional program,Transcription factor,nan,"TP53,BCC7,BMFS5,LFS1,P53,TRP53",yes,P04637
ENSG00000113520,IL4,Autophagy gene expression,STAT6 transcriptional program,Modulator of STAT6 activity,nan,"IL4,BCGF-1,BCGF1,BSF-1,BSF1,IL-4",no,P05112
ENSG00000169194,IL13,Autophagy gene expression,STAT6 transcriptional program,Modulator of STAT6 activity,nan,"IL13,IL-13,P600",yes,P35225
ENSG00000142208,AKT1,Autophagy gene expression,FOXO transcriptional program,Modulator of FOXO1 and FOXO3 activity,nan,"AKT1,AKT,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA",yes,P31749
ENSG00000100644,HIF1A,Autophagy gene expression,HIF1A transcriptional program,Transcription factor,nan,"HIF1A,HIF-1-alpha,HIF-1A,HIF-1alpha,HIF1,HIF1-ALPHA,MOP1,PASD8,bHLHe78",yes,Q16665
ENSG00000172216,CEBPB,Autophagy gene expression,ATF6/CEBPB transcriptional program,Transcription factor,nan,"CEBPB,C/EBP-beta,IL6DBP,NF-IL6,TCF5",yes,P17676
ENSG00000118689,FOXO3,Autophagy gene expression,FOXO transcriptional program,Transcription factor,nan,"FOXO3,AF6q21,FKHRL1,FKHRL1P2,FOXO2,FOXO3A",yes,O43524
ENSG00000143514,TP53BP2,Autophagy gene expression,NFkB transcriptional program,Inhibitor of NFkB transcription factor,nan,"TP53BP2,53BP2,ASPP2,BBP,P53BP2,PPP1R13A",yes,Q13625
ENSG00000237693,IRGM,Autophagy gene expression,NFkB transcriptional program,Inflammation related autophagy regulation,nan,"IRGM,IFI1,IRGM1,LRG-47,LRG47",no,A1A4Y4
ENSG00000150907,FOXO1,Autophagy gene expression,FOXO transcriptional program,Transcription factor,nan,"FOXO1,FKH1,FKHR,FOXO1A",yes,Q12778
ENSG00000198911,SREBF2,Autophagy gene expression,SREBF2 transcriptional program,Transcription factor,nan,"SREBF2,SREBP2,bHLHd2,SREBP-2",yes,Q12772
ENSG00000132109,TRIM21,Autophagy gene expression,IRF8 transcriptional program,Modulator of IRF8 activity,nan,"TRIM21,RNF81,RO52,Ro/SSA,SSA,SSA1",yes,P19474
ENSG00000112561,TFEB,Autophagy gene expression,TFEB transcriptional program,Transcription factor,nan,"TFEB,ALPHATFEB,BHLHE35,TCFEB",yes,P19484
ENSG00000108953,YWHAE,Autophagy gene expression,TFEB transcriptional program,Modulator of TFEB activity,nan,"YWHAE,14-3-3E,HEL2,KCIP-1,MDCR,MDS",yes,P62258
ENSG00000170027,YWHAG,Autophagy gene expression,TFEB transcriptional program,Modulator of TFEB activity,nan,"YWHAG,14-3-3GAMMA,EIEE56,PPP1R170",yes,P61981
ENSG00000100811,YY1,Autophagy gene expression,TFEB transcriptional program,Modulator of TFEB activity,nan,"YY1,DELTA,GADEVS,INO80S,NF-E1,UCRBP,YIN-YANG-1",yes,P25490
ENSG00000128272,ATF4,Autophagy gene expression,ATF4 transcriptional program,Transcription factor,nan,"ATF4,CREB-2,CREB2,TAXREB67,TXREB",yes,P18848
ENSG00000055332,EIF2AK2,Autophagy gene expression,ATF4 transcriptional program,Inflammation related autophagy regulation,nan,"EIF2AK2,EIF2AK1,LEUDEN,PKR,PPP1R83,PRKR",yes,P19525
ENSG00000134001,EIF2S1,Autophagy gene expression,ATF4 transcriptional program,Inflammation related autophagy regulation,nan,"EIF2S1,EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A",yes,P05198
ENSG00000172071,EIF2AK3,Autophagy gene expression,ATF4 transcriptional program,ER stress signaling pathway,nan,"EIF2AK3,PEK,PERK,WRS",yes,Q9NZJ5
ENSG00000086991,NOX4,Autophagy gene expression,ATF4 transcriptional program,ER stress signaling pathway,nan,"NOX4,KOX,KOX-1,RENOX",yes,Q9NPH5
ENSG00000128829,EIF2AK4,Autophagy gene expression,ATF4 transcriptional program,Nutrient sensing,nan,"EIF2AK4,GCN2,PVOD2",yes,Q9P2K8
ENSG00000109320,NFKB1,Autophagy gene expression,NFkB transcriptional program,Component of NFkB transcription factor,nan,"NFKB1,CVID12,EBP-1,KBF1,NF-kB,NF-kB1,NF-kappa-B1,NF-kappaB,NF-kappabeta,NFKB-p105,NFKB-p50,NFkappaB",yes,P19838
ENSG00000077150,NFKB2,Autophagy gene expression,NFkB transcriptional program,Component of NFkB transcription factor,nan,"NFKB2,CVID10,H2TF1,LYT-10,LYT10,NF-kB2,p100,p49/p100,p52",yes,Q00653
ENSG00000162924,REL,Autophagy gene expression,NFkB transcriptional program,Component of NFkB transcription factor,nan,"REL,C-Rel",yes,Q04864
ENSG00000173039,RELA,Autophagy gene expression,NFkB transcriptional program,Component of NFkB transcription factor,nan,"RELA,CMCU,NFKB3,p65",yes,Q04206
ENSG00000104856,RELB,Autophagy gene expression,NFkB transcriptional program,Component of NFkB transcription factor,nan,"RELB,I-REL,IMD53,IREL,REL-B",yes,Q01201
ENSG00000111537,IFNG,Autophagy gene expression,NFkB transcriptional program,Inflammation related autophagy regulation,nan,"IFNG,IFG,IFI,IMD69",yes,P01579
ENSG00000080561,MID2,Autophagy gene expression,NFkB transcriptional program,Inflammation related autophagy regulation,nan,"MID2,FXY2,MRX101,RNF60,TRIM1",yes,Q9UJV3
ENSG00000171206,TRIM8,Autophagy gene expression,NFkB transcriptional program,Inflammation related autophagy regulation,nan,"TRIM8,GERP,RNF27",yes,Q9BZR9
ENSG00000141569,TRIM65,Autophagy gene expression,NFkB transcriptional program,Inflammation related autophagy regulation,nan,"TRIM65,4732463G12Rik",yes,Q6PJ69
ENSG00000110330,BIRC2,Autophagy gene expression,NFkB transcriptional program,Activator of NFkB activity,nan,"BIRC2,API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1",yes,Q13490
ENSG00000100906,NFKBIA,Autophagy gene expression,NFkB transcriptional program,Inhibitor of NFkB transcription factor,nan,"NFKBIA,EDAID2,IKBA,MAD-3,NFKBI",yes,P25963
ENSG00000104825,NFKBIB,Autophagy gene expression,NFkB transcriptional program,Inhibitor of NFkB transcription factor,nan,"NFKBIB,IKBB,TRIP9",yes,Q15653
ENSG00000170345,FOS,Autophagy gene expression,AP-1 transcriptional program,Component of AP-1 transcription factor,nan,"FOS,AP-1,C-FOS,p55",yes,P01100
ENSG00000125740,FOSB,Autophagy gene expression,AP-1 transcriptional program,Component of AP-1 transcription factor,nan,"FOSB,AP-1,G0S3,GOS3,GOSB",yes,P53539
ENSG00000175592,FOSL1,Autophagy gene expression,AP-1 transcriptional program,Component of AP-1 transcription factor,nan,"FOSL1,FRA,FRA1,fra-1",yes,P15407
ENSG00000075426,FOSL2,Autophagy gene expression,AP-1 transcriptional program,Component of AP-1 transcription factor,nan,"FOSL2,FRA2",yes,P15408
ENSG00000177606,JUN,Autophagy gene expression,AP-1 transcriptional program,Component of AP-1 transcription factor,nan,"JUN,AP-1,AP1,c-Jun,cJUN,p39",yes,P05412
ENSG00000149295,DRD2,Autophagy gene expression,AP-1 transcriptional program,Activator of AP-1 transcription factor,nan,"DRD2,D2DR,D2R",yes,P14416
ENSG00000151577,DRD3,Autophagy gene expression,AP-1 transcriptional program,Activator of AP-1 transcription factor,nan,"DRD3,D3DR,ETM1,FET1",no,P35462
ENSG00000176046,NUPR1,Autophagy gene expression,FOXO transcriptional program,Modulator of FOXO3 activity,nan,"NUPR1,COM1,P8",yes,O60356
ENSG00000140968,IRF8,Autophagy gene expression,IRF8 transcriptional program,Transcription factor,nan,"IRF8,H-ICSBP,ICSBP,ICSBP1,IMD32A,IMD32B,IRF-8",yes,Q02556
ENSG00000066294,CD84,Autophagy gene expression,IRF8 transcriptional program,Modulator of IRF8 activity,nan,"CD84,LY9B,SLAMF5,hCD84,mCD84",yes,Q9UIB8
ENSG00000116044,NFE2L2,Autophagy gene expression,NFE2L2 transcriptional program,Transcription factor,nan,"NFE2L2,HEBP1,IMDDHH,NRF2,Nrf-2",yes,Q16236
ENSG00000079999,KEAP1,Autophagy gene expression,NFE2L2 transcriptional program,Modulator of NRF2 activity,nan,"KEAP1,INrf2,KLHL19",yes,Q14145
ENSG00000168610,STAT3,Autophagy gene expression,STAT3 transcriptional program,Transcription factor,nan,"STAT3,ADMIO,ADMIO1,APRF,HIES",yes,P40763
ENSG00000136634,IL10,Autophagy gene expression,STAT3 transcriptional program,Inflammation related autophagy regulation,nan,"IL10,CSIF,GVHDS,IL-10,IL10A,TGIF",no,P22301
ENSG00000110324,IL10RA,Autophagy gene expression,STAT3 transcriptional program,Inflammation related autophagy regulation,nan,"IL10RA,CD210,CD210a,CDW210A,HIL-10R,IL-10R1,IL10R",yes,Q13651
ENSG00000166888,STAT6,Autophagy gene expression,STAT6 transcriptional program,Transcription factor,nan,"STAT6,D12S1644,IL-4-STAT,STAT6B,STAT6C",yes,P42226
ENSG00000068323,TFE3,Autophagy gene expression,TFE3 transcriptional program,Transcription factor,nan,"TFE3,RCCP2,RCCX1,TFEA,bHLHe33",yes,P19532
ENSG00000102145,GATA1,Autophagy gene expression,GATA1 transcriptional program,Transcription factor,nan,"GATA1,GF1,GF-1,NFE1,XLTT,ERYF1,NF-E1,XLANP,XLTDA,GATA-1,HAEADA",yes,P15976
ENSG00000136574,GATA4,Autophagy gene expression,GATA4 transcriptional program,Transcription factor,nan,"GATA4,ASD2,TACHD,TOF,VSD1",yes,P43694
ENSG00000073282,TP63,Autophagy gene expression,TP63 transcriptional program,Transcription factor,nan,"TP63,AIS,B(p51A),B(p51B),EEC3,KET,LMS,NBP,OFC8,RHS,SHFM4,TP53CP,TP53L,TP73L,p40,p51,p53CP,p63,p73H,p73L",yes,Q9H3D4
ENSG00000078900,TP73,Autophagy gene expression,TP73 transcriptional program,Transcription factor,nan,"TP73,P73",yes,O15350
ENSG00000118217,ATF6,Autophagy gene expression,ATF6/CEBPB transcriptional program,Transcription factor,nan,"ATF6,ACHM7,ATF6A",yes,P18850
ENSG00000168036,CTNNB1,Autophagy gene expression,TCF7L2 transcriptional program,Repressor of TCF7L2 activity,nan,"CTNNB1,EVR7,CTNNB,MRD19,NEDSDV,armadillo",yes,P35222
ENSG00000148737,TCF7L2,Autophagy gene expression,TCF7L2 transcriptional program,Transcription factor,nan,"TCF7L2,TCF4,TCF-4",yes,Q9NQB0
ENSG00000175197,DDIT3,Autophagy gene expression,DDIT3 transcriptional program,Transcription factor,nan,"DDIT3,CHOP,CEBPZ,CHOP10,CHOP-10,GADD153,AltDDIT3,C/EBPzeta",yes,P35638
ENSG00000101412,E2F1,Autophagy gene expression,E2F1 transcriptional program,Transcription factor,nan,"E2F1,RBP3,E2F-1,RBAP1,RBBP3",yes,Q01094
ENSG00000181449,SOX2,Autophagy gene expression,SOX2 transcriptional program,Transcription factor,nan,"SOX2,ANOP3,MCOPS3",yes,P48431
ENSG00000169136,ATF5,Autophagy gene expression,ATF5 transcriptional program,Transcription factor,nan,"ATF5,ATFX,HMFN0395",yes,Q9Y2D1
ENSG00000018408,WWTR1,Autophagy gene expression,Transcriptional coactivator,Cellular mechanics sensing,nan,"WWTR1,TAZ",yes,Q9GZV5
ENSG00000137693,YAP1,Autophagy gene expression,Transcriptional coactivator,Cellular mechanics sensing,nan,"YAP1,COB1,YAP,YAP2,YAP65,YKI",yes,P46937
ENSG00000089280,FUS,Autophagy gene expression,Transcriptional regulator,nan,nan,"FUS,ALS6,ETM4,FUS1,HNRNPP2,POMP75,TLS",yes,P35637
ENSG00000012504,NR1H4,Autophagy gene expression,Transcriptional regulator,nan,nan,"NR1H4,BAR,FXR,HRR-1,HRR1,PFIC5,RIP14",yes,Q96RI1
ENSG00000189298,ZKSCAN3,Autophagy gene expression,Transcriptional repressor,nan,nan,"ZKSCAN3,ZF47,ZFP306,ZNF306,ZNF309,ZSCAN13,ZSCAN35,Zfp47,dJ874C20.1,dJ874C20.1.,zfp-47",yes,Q9BRR0
ENSG00000204209,DAXX,Autophagy gene expression,Transcriptional repressor,nan,nan,"DAXX,BING2,DAP6,EAP1,SMIM40",yes,Q9UER7
ENSG00000115415,STAT1,Autophagy gene expression,Transcriptional repressor,nan,nan,"STAT1,CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91",yes,P42224
ENSG00000114867,EIF4G1,Autophagy gene expression,Translational modulator,nan,nan,"EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18",yes,Q04637
ENSG00000159217,IGF2BP1,Autophagy gene expression,Translational modulator,nan,nan,"IGF2BP1,CRD-BP,CRDBP,IMP-1,IMP1,VICKZ1,ZBP1",yes,Q9NZI8
ENSG00000066044,ELAVL1,Autophagy gene expression,Translational modulator,nan,nan,"ELAVL1,ELAV1,HUR,Hua,MelG",yes,Q15717
ENSG00000106462,EZH2,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"EZH2,ENX-1,ENX1,EZH2b,KMT6,KMT6A,WVS,WVS2",yes,Q15910
ENSG00000103510,KAT8,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"KAT8,LIGOWS,MOF,MYST1,ZC2HC8,hMOF",yes,Q9H7Z6
ENSG00000066135,KDM4A,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"KDM4A,JHDM3A,JMJD2,JMJD2A,TDRD14A",yes,O75164
ENSG00000204371,EHMT2,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"EHMT2,BAT8,C6orf30,G9A,GAT8,KMT1C,NG36",yes,Q96KQ7
ENSG00000164916,FOXK1,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"FOXK1,FOXK1L",yes,P85037
ENSG00000141568,FOXK2,Autophagy gene expression,Epigenetic autophagy regulation,Suppressor of autophagy gene transcription,nan,"FOXK2,ILF,ILF-1,ILF1,nGTBP",yes,Q01167
ENSG00000183735,TBK1,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"TBK1,FTDALS4,IIAE8,NAK,T2K",yes,Q9UHD2
ENSG00000184743,ATL3,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"ATL3,HSN1F",yes,Q6DD88
ENSG00000176171,BNIP3,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"BNIP3,NIP3",yes,Q12983
ENSG00000104765,BNIP3L,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"BNIP3L,BNIP3a,NIX",yes,O60238
ENSG00000165280,VCP,Autophagy substrate selection,Marking substrates for selective autophagy,Lysophagy,ELDR complex component,"VCP,CDC48,TERA,p97",yes,P55072
ENSG00000140941,MAP1LC3B,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"MAP1LC3B,ATG8F,LC3B,MAP1A/1BLC3,MAP1LC3B-a",yes,Q9GZQ8
ENSG00000170296,GABARAP,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"GABARAP,ATG8A,GABARAP-a,MM46",yes,O95166
ENSG00000139112,GABARAPL1,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"GABARAPL1,APG8-LIKE,APG8L,ATG8,ATG8B,ATG8L,GEC1",yes,Q9H0R8
ENSG00000161011,SQSTM1,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B",yes,Q13501
ENSG00000038532,CLEC16A,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"CLEC16A,Gop-1,KIAA0350",yes,Q2KHT3
ENSG00000158828,PINK1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"PINK1,BRPK,PARK6",yes,Q9BXM7
ENSG00000175193,PARL,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"PARL,PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1",yes,Q9H300
ENSG00000185345,PARK2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"PRKN,AR-JP,LPRS2,PARK2,PDJ",yes,O60260
ENSG00000247077,PGAM5,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"PGAM5,BXLBV68",yes,Q96HS1
ENSG00000130770,ATPIF1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"ATP5IF1,ATPI,ATPIF1,ATPIP,IP",yes,Q9UII2
ENSG00000196683,TOMM7,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"TOMM7,TOM7",yes,Q9P0U1
ENSG00000181852,RNF41,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"RNF41,FLRF,NRDP1,SBBI03",yes,Q9H4P4
ENSG00000138592,USP8,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"USP8,HumORF8,PITA4,SPG59,UBPY",yes,P40818
ENSG00000090432,MUL1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"MUL1,C1orf166,GIDE,MAPL,MULAN,RNF218",yes,Q969V5
ENSG00000196470,SIAH1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SIAH1,SIAH1A",yes,Q8IUQ4
ENSG00000064692,SNCAIP,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SNCAIP,SYPH1,Sph1",yes,Q9Y6H5
ENSG00000166233,ARIH1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"ARIH1,ARI,HARI,HHARI,UBCH7BP",yes,Q9Y4X5
ENSG00000159399,HK2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"HK2,HKII,HXK2",yes,P52789
ENSG00000151729,SLC25A4,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SLC25A4,AAC1,ANT,ANT 1,ANT1,MTDPS12,MTDPS12A,PEO2,PEO3,PEOA2,T1",yes,P12235
ENSG00000005022,SLC25A5,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SLC25A5,2F1,AAC2,ANT2,T2,T3",yes,P05141
ENSG00000072310,SREBF1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SREBF1,SREBP1,bHLHd1",yes,P36956
ENSG00000198911,SREBF2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"SREBF2,SREBP-2,SREBP2,bHLHd2",yes,Q12772
ENSG00000213585,VDAC1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"VDAC1,PORIN,VDAC-1",yes,P21796
ENSG00000197785,ATAD3A,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"ATAD3A,HAYOS,PHRINL",yes,Q9NVI7
ENSG00000132305,IMMT,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"IMMT,HMP,MICOS60,MINOS2,Mic60,P87,P87/89,P89,PIG4,PIG52",yes,Q16891
ENSG00000072518,MARK2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,PINK/PRKN pathway,"MARK2,EMK-1,EMK1,PAR-1,Par-1b,Par1b",yes,Q7KZI7
ENSG00000131508,UBE2D2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Ubiquitination of mitochondrial proteins,"UBE2D2,E2(17)KB2,PUBC1,UBC4,UBC4/5,UBCH4,UBCH5B",yes,P62837
ENSG00000109332,UBE2D3,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Ubiquitination of mitochondrial proteins,"UBE2D3,E2(17)KB3,UBC4/5,UBCH5C",yes,P61077
ENSG00000185651,UBE2L3,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Ubiquitination of mitochondrial proteins,"UBE2L3,E2-F1,L-UBC,UBCH7,UbcM4",yes,P68036
ENSG00000177889,UBE2N,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Ubiquitination of mitochondrial proteins,"UBE2N,UBC13,UbcH13,UBCHBEN,HEL-S-71,UbcH-ben,UBCHBEN,UBC13",yes,P61088
ENSG00000135655,USP15,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Deubiquitination of mitochondrial proteins,"USP15,UNPH-2,UNPH4",yes,Q9Y4E8
ENSG00000135093,USP30,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Deubiquitination of mitochondrial proteins,"USP30,-",yes,Q70CQ3
ENSG00000118369,USP35,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Deubiquitination of mitochondrial proteins,"USP35,-",yes,Q9P2H5
ENSG00000100300,TSPO,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Inhibits mitochondrial protein ubiquitination,"TSPO,BPBS,BZRP,DBI,IBP,MBR,PBR,PBS,PKBS,PTBR,mDRC,pk18",yes,P30536
ENSG00000184117,NIPSNAP1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Recruitment of cargo adapters,"NIPSNAP1,-",yes,Q9BPW8
ENSG00000146729,GBAS,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Recruitment of cargo adapters,"NIPSNAP2,GBAS",yes,O75323
ENSG00000086758,HUWE1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Direct recruitment of AMBRA1,"HUWE1,ARF-BP1,HECTH9,HSPC272,Ib772,LASU1,MRXST,MULE,URE-B1,UREB1",yes,Q7Z6Z7
ENSG00000171109,MFN1,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Modulator of mitochondrial morphology-induced mitophagy,"MFN1,hfzo1,hfzo2",yes,Q8IWA4
ENSG00000116688,MFN2,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Modulator of mitochondrial morphology-induced mitophagy,"MFN2,CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,HMSN6A,HSG,MARF",yes,O95140
ENSG00000087470,DNM1L,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Modulator of mitochondrial morphology-induced mitophagy,"DNM1L,DLP1,DRP1,DVLP,DYMPLE,EMPF,EMPF1,HDYNIV,OPA5",yes,O00429
ENSG00000116288,PARK7,Autophagy substrate selection,Marking substrates for selective autophagy,Mitophagy,Modulator of mitochondrial morphology-induced mitophagy,"PARK7,DJ-1,DJ1,GATD2,HEL-S-67p",yes,Q99497
ENSG00000204977,TRIM13,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,Ubiquitination of ER proteins,"TRIM13,CAR,DLEU5,LEU5,RFP2,RNF77",yes,O60858
ENSG00000198171,DDRGK1,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,UFMylation of ER proteins,"DDRGK1,C20orf116,SEMDSH,UFBP1,dJ1187M17.3",yes,Q96HY6
ENSG00000014123,UFL1,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,UFMylation of ER proteins,"UFL1,KIAA0776,Maxer,NLBP,RCAD",yes,O94874
ENSG00000081307,UBA5,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,UFMylation of ER proteins,"UBA5,EIEE44,SCAR24,THIFP1,UBE1DC1",yes,Q9GZZ9
ENSG00000143222,UFC1,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,UFMylation of ER proteins,"UFC1,HSPC155,NEDSG",yes,Q9Y3C8
ENSG00000120686,UFM1,Autophagy substrate selection,Marking substrates for selective autophagy,ERphagy,UFMylation of ER proteins,"UFM1,BM-002,C13orf20,HLD14",yes,P61960
ENSG00000139197,PEX5,Autophagy substrate selection,Marking substrates for selective autophagy,Pexophagy,nan,"PEX5,PBD2A,PBD2B,PTS1-BP,PTS1R,PXR1,RCDP5",yes,P50542
ENSG00000148356,LRSAM1,Autophagy substrate selection,Marking substrates for selective autophagy,Xenophagy,nan,"LRSAM1,CMT2P,RIFLE,TAL",yes,Q6UWE0
ENSG00000040633,PHF23,Autophagy substrate selection,Marking substrates for selective autophagy,Xenophagy,nan,"PHF23,hJUNE-1b",yes,Q9BUL5
ENSG00000158717,RNF166,Autophagy substrate selection,Marking substrates for selective autophagy,Xenophagy,Catalyzes K33-linked ubiquitination of p62,"RNF166,-",yes,Q96A37
ENSG00000115307,AUP1,Autophagy substrate selection,Marking substrates for selective autophagy,Lipophagy,Ubiquitination of lipid droplet surface proteins,"AUP1,-",yes,Q9Y679
ENSG00000184787,UBE2G2,Autophagy substrate selection,Marking substrates for selective autophagy,Lipophagy,Ubiquitination of lipid droplet surface proteins,"UBE2G2,UBC7",yes,P60604
ENSG00000075785,RAB7A,Autophagy substrate selection,Marking substrates for selective autophagy,Lipophagy,Recruiting autophagy factors to lipid droplets,"RAB7A,CMT2B,PRO2706,RAB7",yes,P51149
ENSG00000276600,RAB7B,Autophagy substrate selection,Marking substrates for selective autophagy,Lipophagy,Recruiting autophagy factors to lipid droplets,"RAB7B,RAB7",yes,Q96AH8
ENSG00000169252,ADRB2,Autophagy substrate selection,Marking substrates for selective autophagy,Lipophagy,Upstream lipophagy signaling,"ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR",yes,P07550
ENSG00000124486,USP9X,Autophagy substrate selection,Marking substrates for selective autophagy,Zymophagy,nan,"USP9X,DFFRX,FAF,FAM,MRX99,MRXS99F",yes,Q93008
ENSG00000123240,OPTN,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"OPTN,ALS12,FIP2,GLC1E,HIP7,HYPL,NRP,TFIIIA-INTP",yes,Q96CV9
ENSG00000136436,CALCOCO2,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"CALCOCO2,NDP52",yes,Q13137
ENSG00000106052,TAX1BP1,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"TAX1BP1,CALCOCO3,T6BP,TXBP151",yes,Q86VP1
ENSG00000069509,FUNDC1,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"FUNDC1,-",yes,Q8IVP5
ENSG00000099968,BCL2L13,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"BCL2L13,BCL-RAMBO,Bcl2-L-13,MIL1",yes,Q9BXK5
ENSG00000105701,FKBP8,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"FKBP8,FKBP38,FKBPr38",yes,Q14318
ENSG00000215021,PHB2,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"PHB2,BAP,BCAP37,Bap37,PNAS-141,REA,hBAP,p22",yes,Q99623
ENSG00000160703,NLRX1,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"NLRX1,CLR11.3,DLNB26,NOD26,NOD5,NOD9",yes,Q86UT6
ENSG00000178952,TUFM,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"TUFM,COXPD4,EF-TuMT,EFTU,P43",yes,P49411
ENSG00000130479,MAP1S,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"MAP1S,BPY2IP1,C19orf5,MAP8,VCY2IP-1,VCY2IP1",yes,Q66K74
ENSG00000121749,TBC1D15,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"TBC1D15,RAB7-GAP",yes,Q8TC07
ENSG00000104946,TBC1D17,Autophagy substrate selection,Selective autophagy receptor,Mitophagy,nan,"TBC1D17,-",yes,Q9HA65
ENSG00000154153,FAM134B,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"RETREG1,FAM134B,JK-1,JK1",yes,Q9H6L5
ENSG00000144567,FAM134A,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"RETREG2,C2orf17,FAM134A,MAG-2",yes,Q8NC44
ENSG00000141699,FAM134C,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"RETREG3,FAM134C",yes,Q86VR2
ENSG00000008952,SEC62,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"SEC62,Dtrp1,HTP1,TLOC1,TP-1",yes,Q99442
ENSG00000133318,RTN3,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"RTN3,ASYIP,HAP,NSPL2,NSPLII,RTN3-A1",yes,O95197
ENSG00000260916,CCPG1,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"CCPG1,CPR8",yes,Q9ULG6
ENSG00000164081,TEX264,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"TEX264,ZSIG11",yes,Q9Y6I9
ENSG00000012822,CALCOCO1,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"CALCOCO1,Cocoa,PP13275,calphoglin",yes,Q9P1Z2
ENSG00000108465,CDK5RAP3,Autophagy substrate selection,Selective autophagy receptor,ERphagy,nan,"CDK5RAP3,C53,HSF-27,IC53,LZAP,MST016,OK/SW-cl.114,PP1553",yes,Q96JB5
ENSG00000188554,NBR1,Autophagy substrate selection,Selective autophagy receptor,Pexophagy,nan,"NBR1,1A1-3B,IAI3B,M17S2,MIG19",yes,Q14596
ENSG00000221926,TRIM16,Autophagy substrate selection,Selective autophagy receptor,Lysophagy,nan,"TRIM16,EBBP",yes,O95361
ENSG00000204311,DFNB59,Autophagy substrate selection,Selective autophagy receptor,Pexophagy,nan,"PJVK,DFNB59",yes,Q0ZLH3
ENSG00000113368,LMNB1,Autophagy substrate selection,Selective autophagy receptor,Nucleophagy,nan,"LMNB1,ADLD,LMN,LMN2,LMNB",yes,P20700
ENSG00000132256,TRIM5,Autophagy substrate selection,Selective autophagy receptor,Xenophagy,nan,"TRIM5,RNF88,TRIM5alpha",yes,Q9C035
ENSG00000078902,TOLLIP,Autophagy substrate selection,Selective autophagy receptor,Aggrephagy,nan,"TOLLIP,IL-1RAcPIP",yes,Q9H0E2
ENSG00000118804,STBD1,Autophagy substrate selection,Selective autophagy receptor,Glycophagy,nan,"STBD1,GENEX3414,GENX-3414",yes,O95210
ENSG00000083635,NUFIP1,Autophagy substrate selection,Selective autophagy receptor,Ribophagy,nan,"NUFIP1,NUFIP,Rsa1,bA540M5.1",yes,Q9UHK0
ENSG00000266412,NCOA4,Autophagy substrate selection,Selective autophagy receptor,Ferritinophagy,nan,"NCOA4,ARA70,ELE1,PTC3,RFG",yes,Q13772
ENSG00000167964,RAB26,Autophagy substrate selection,Selective autophagy receptor,Synaptophagy,nan,"RAB26,V46133",yes,Q9ULW5
ENSG00000162931,TRIM17,Autophagy substrate selection,Selective autophagy receptor,Midbody autophagy,nan,"TRIM17,RBCC,RNF16,terf",yes,Q9Y577
ENSG00000103313,MEFV,Autophagy substrate selection,Selective autophagy receptor,Individual substrates,nan,"MEFV,FMF,MEF,PAAND,TRIM20",yes,O15553
ENSG00000100347,SAMM50,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Mitophagy,PINK/PRKN pathway,"SAMM50,CGI-51,OMP85,SAM50,TOB55,TRG-3,YNL026W",yes,Q9Y512
ENSG00000100225,FBXO7,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Mitophagy,PINK/PRKN pathway,"FBXO7,FBX,FBX07,FBX7,PARK15,PKPS",yes,Q9Y3I1
ENSG00000107897,ACBD5,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Pexophagy,nan,"ACBD5,RDLKD",yes,Q5T8D3
ENSG00000137055,PLAA,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Lysophagy,ELDR complex component,"PLAA,DOA1,NDMSBA,PLA2P,PLAP",yes,Q9Y263
ENSG00000180667,YOD1,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Lysophagy,ELDR complex component,"YOD1,DUBA8,OTUD2,PRO0907",yes,Q5VVQ6
ENSG00000167671,UBXN6,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Lysophagy,ELDR complex component,"UBXN6,UBXD1,UBXDC2",yes,Q9BZV1
ENSG00000163625,WDFY3,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,Aggrephagy,nan,"WDFY3,ALFY,BCHS,MCPH18,ZFYVE25",yes,Q8IZQ1
ENSG00000048707,VPS13D,Autophagy substrate selection,Substrate selectivity regulator for selective autophagy,nan,nan,"VPS13D,SCAR4",yes,Q5THJ4
ENSG00000132109,TRIM21,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"TRIM21,RNF81,RO52,Ro/SSA,SSA,SSA1",yes,P19474
ENSG00000109819,PPARGC1A,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"PPARGC1A,LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1A,PPARGC1",yes,Q9UBK2
ENSG00000101255,TRIB3,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"TRIB3,C20orf97,NIPK,SINK,SKIP3,TRB3",yes,Q96RU7
ENSG00000055483,USP36,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"USP36,DUB1",yes,Q9P275
ENSG00000108654,DDX5,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"DDX5,G17P1,HLR1,HUMP68,p68",yes,P17844
ENSG00000129465,RIPK3,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"RIPK3,RIP3",yes,Q9Y572
ENSG00000145604,SKP2,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"SKP2,FBL1,FBXL1,FLB1,p45",yes,Q13309
ENSG00000069869,NEDD4,Autophagy substrate selection,Autophagy receptor regulation,SQSTM1 regulation,nan,"NEDD4,NEDD4-1,RPF1",yes,P46934
ENSG00000113734,BNIP1,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"BNIP1,NIP1,SEC20,TRG-8",yes,Q12981
ENSG00000138942,RNF185,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"RNF185,-",yes,Q96GF1
ENSG00000198060,5-Mar,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"MARCHF5,MARCH-V,MARCH5,MITOL,RNF153",yes,Q9NX47
ENSG00000136560,TANK,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"TANK,I-TRAF,ITRAF,TRAF2",yes,Q92844
ENSG00000187109,NAP1L1,Autophagy substrate selection,Autophagy receptor regulation,Mitophagy,nan,"NAP1L1,NAP1,NAP1L,NRP",yes,P55209
ENSG00000116977,LGALS8,Autophagy substrate selection,Autophagy receptor regulation,Xenophagy,nan,"LGALS8,Gal-8,PCTA-1,PCTA1,Po66-CBP",yes,O00214
ENSG00000163512,AZI2,Autophagy substrate selection,Autophagy receptor regulation,Xenophagy,nan,"AZI2,AZ2,NAP1,TILP",yes,Q9H6S1
ENSG00000154710,RABGEF1,Autophagy substrate selection,Autophagosome formation for selective autophagy,Mitophagy,nan,"RABGEF1,RABEX5,RAP1,rabex-5",yes,Q9UJ41
ENSG00000124839,RAB17,Autophagy substrate selection,Autophagosome formation for selective autophagy,Xenophagy,nan,"RAB17,-",yes,Q9H0T7
ENSG00000112210,RAB23,Autophagy substrate selection,Autophagosome formation for selective autophagy,Xenophagy,nan,"RAB23,HSPC137",yes,Q9ULC3
ENSG00000101460,MAP1LC3A,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"MAP1LC3A,ATG8E,LC3,LC3A,MAP1ALC3,MAP1BLC3",yes,Q9H492
ENSG00000197769,MAP1LC3C,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"MAP1LC3C,ATG8J,LC3C",yes,Q9BXW4
ENSG00000034713,GABARAPL2,Autophagy substrate selection,Autophagy receptor recognition,Recognized via LIRs in receptors for several forms of selective autophagy,ATG8 homolog,"GABARAPL2,ATG8,ATG8C,GATE-16,GATE16,GEF-2,GEF2",yes,P60520
ENSG00000163071,SPATA18,Autophagy substrate selection,Specific function in autophagy substrate selection unknown,nan,nan,"SPATA18,Mieap,SPETEX1",yes,Q8TC71
ENSG00000198836,OPA1,Autophagy substrate selection,Specific function in autophagy substrate selection unknown,nan,nan,"OPA1,BERHS,MGM1,MTDPS14,NPG,NTG,largeG",yes,O60313
ENSG00000131943,C19orf12,Autophagy substrate selection,none,Mitophagy,none,none,yes,none
ENSG00000005893,LAMP2,Chaperone directed autophagy,Chaperone mediated autophagy,Receptor for chaperone-mediated autophagy,nan,"LAMP2,CD107b,DND,LAMP-2,LAMPB,LGP-96,LGP110",yes,P13473
ENSG00000109971,HSPA8,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"HSPA8,HEL-33,HEL-S-72p,HSC54,HSC70,HSC71,HSP71,HSP73,HSPA10,LAP-1,LAP1,NIP71",yes,P11142
ENSG00000132002,DNAJB1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"DNAJB1,HSPF1,Hdj1,Hsp40,RSPH16B,Sis1",yes,P25685
ENSG00000131095,GFAP,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"GFAP,ALXDRD",yes,P14136
ENSG00000156508,EEF1A1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"EEF1A1,CCS-3,CCS3,EE1A1,EEF-1,EEF1A,EF-Tu,EF1A,GRAF-1EF,LENG7,PTI1,eEF1A-1",yes,P68104
ENSG00000101210,EEF1A2,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"EEF1A2,EEF1AL,EF-1-alpha-2,EF1A,EIEE33,HS1,MRD38,STN,STNL",yes,Q05639
ENSG00000081913,PHLPP1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"PHLPP1,PHLPP,PLEKHE1,PPM3A,SCOP",yes,O60346
ENSG00000136238,RAC1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"RAC1,MIG5,MRD48,Rac-1,TC-25,p21-Rac1",yes,P63000
ENSG00000120885,CLU,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate delivery,nan,"CLU,AAG4,APO-J,APOJ,CLI,CLU1,CLU2,KUB1,NA1/NA2,SGP-2,SGP2,SP-40,TRPM-2,TRPM2",yes,P10909
ENSG00000080824,HSP90AA1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate selection,nan,"HSP90AA1,EL52,HEL-S-65p,HSP86,HSP89A,HSP90A,HSP90N,HSPC1,HSPCA,HSPCAL1,HSPCAL4,HSPN,Hsp103,Hsp89,Hsp90,LAP-2,LAP2",yes,P07900
ENSG00000103266,STUB1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate selection,nan,"STUB1,CHIP,HSPABP2,NY-CO-7,SCA48,SCAR16,SDCCAG7,UBOX1",yes,Q9UNE7
ENSG00000168439,STIP1,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate selection,nan,"STIP1,HEL-S-94n,HOP,IEF-SSP-3521,P60,STI1,STI1L",yes,P31948
ENSG00000100380,ST13,Chaperone directed autophagy,Chaperone mediated autophagy,Substrate selection,nan,"ST13,AAG2,FAM10A1,FAM10A4,HIP,HOP,HSPABP,HSPABP1,P48,PRO0786,SNC6",yes,P50502
ENSG00000107262,BAG1,Chaperone directed autophagy,Chaperone assisted selective autophagy,Substrate delivery,nan,"BAG1,BAG-1,HAP,RAP46",yes,Q99933
ENSG00000151929,BAG3,Chaperone directed autophagy,Chaperone assisted selective autophagy,Substrate delivery,nan,"BAG3,BAG-3,BIS,CAIR-1,MFM6",yes,O95817
ENSG00000172403,SYNPO2,Chaperone directed autophagy,Chaperone assisted selective autophagy,Substrate delivery,nan,"SYNPO2,-",yes,Q9UMS6
ENSG00000152137,HSPB8,Chaperone directed autophagy,Chaperone assisted selective autophagy,Substrate selection,nan,"HSPB8,CMT2L,DHMN2,E2IG1,H11,HMN2,HMN2A,HSP22",yes,Q9UJY1
ENSG00000033627,ATP6V0A1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0A1,ATP6N1,ATP6N1A,Stv1,VPP1,Vph1,a1",yes,Q93050
ENSG00000185344,ATP6V0A2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0A2,A2,ARCL,ARCL2A,ATP6A2,ATP6N1D,J6B7,RTF,STV1,TJ6,TJ6M,TJ6S,VPH1,WSS",yes,Q9Y487
ENSG00000110719,TCIRG1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"TCIRG1,ATP6N1C,ATP6V0A3,Atp6i,OC-116kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3",yes,Q13488
ENSG00000105929,ATP6V0A4,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0A4,A4,ATP6N1B,ATP6N2,DRTA3,RDRTA2,RTA1C,RTADR,STV1,VPH1,VPP2",yes,Q9HBG4
ENSG00000117410,ATP6V0B,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0B,ATP6F,HATPL,VMA16",yes,Q99437
ENSG00000185883,ATP6V0C,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0C,ATP6C,ATP6L,ATPL,VATL,VPPC,Vma3",yes,P27449
ENSG00000159720,ATP6V0D1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0D1,ATP6D,ATP6DV,P39,VATX,VMA6,VPATPD",yes,P61421
ENSG00000147614,ATP6V0D2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0D2,ATP6D2,VMA6",no,Q8N8Y2
ENSG00000113732,ATP6V0E1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0E1,ATP6H,ATP6V0E,M9.2,Vma21,Vma21p",yes,O15342
ENSG00000171130,ATP6V0E2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V0 lysosomal v-ATPase proton pump component,"ATP6V0E2,ATP6V0E2L,C7orf32",yes,Q8NHE4
ENSG00000114573,ATP6V1A,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1A,ARCL2D,ATP6A1,ATP6V1A1,HO68,IECEE3,VA68,VPP2,Vma1",yes,P38606
ENSG00000116039,ATP6V1B1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1B1,ATP6B1,DRTA2,RTA1B,VATB,VMA2,VPP3",yes,P15313
ENSG00000147416,ATP6V1B2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1B2,ATP6B1B2,ATP6B2,DOOD,HO57,VATB,VPP3,Vma2,ZLS2",yes,P21281
ENSG00000155097,ATP6V1C1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1C1,ATP6C,ATP6D,VATC,Vma5",yes,P21283
ENSG00000143882,ATP6V1C2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1C2,ATP6C2,VMA5",yes,Q8NEY4
ENSG00000100554,ATP6V1D,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1D,ATP6M,VATD,VMA8",yes,Q9Y5K8
ENSG00000131100,ATP6V1E1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1E1,ARCL2C,ATP6E,ATP6E2,ATP6V1E,P31,Vma4",yes,P36543
ENSG00000250565,ATP6V1E2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1E2,ATP6E1,ATP6EL2,ATP6V1EL2,VMA4",yes,Q96A05
ENSG00000128524,ATP6V1F,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1F,ATP6S14,VATF,Vma7",yes,Q16864
ENSG00000136888,ATP6V1G1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1G1,ATP6G,ATP6G1,ATP6GL,ATP6J,Vma10",yes,O75348
ENSG00000213760,ATP6V1G2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1G2,ATP6G,ATP6G2,NG38,VMA10",yes,O95670
ENSG00000151418,ATP6V1G3,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1G3,ATP6G3,Vma10",no,Q96LB4
ENSG00000047249,ATP6V1H,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,V1 lysosomal v-ATPase proton pump component,"ATP6V1H,CGI-11,MSTP042,NBP1,SFD,SFDalpha,SFDbeta,VMA13",yes,Q9UI12
ENSG00000071553,ATP6AP1,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,Regulator of the lysosomal v-ATPase proton pump,"ATP6AP1,16A,ATP6IP1,ATP6S1,Ac45,CF2,VATPS1,XAP-3,XAP3",yes,Q15904
ENSG00000182220,ATP6AP2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,Regulator of the lysosomal v-ATPase proton pump,"ATP6AP2,APT6M8-9,ATP6IP2,ATP6M8-9,CDG2R,ELDF10,HT028,M8-9,MRXE,MRXSH,MSTP009,PRR,RENR,XMRE,XPDS",yes,O75787
ENSG00000188906,LRRK2,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,Regulator of the lysosomal v-ATPase proton pump,"LRRK2,AURA17,DARDARIN,PARK8,RIPK7,ROCO2",yes,Q5S007
ENSG00000038532,CLEC16A,Lysosomal catabolism,Specific role in lysosomal catabolism unknown,nan,nan,"CLEC16A,Gop-1,KIAA0350",yes,Q2KHT3
ENSG00000112367,FIG4,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal membrane homeostasis,nan,"FIG4,ALS11,BTOP,CMT4J,KIAA0274,SAC3,YVS,dJ249I4.1",yes,Q92562
ENSG00000064601,CTSA,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSA,GLB2,GSL,NGBE,PPCA,PPGB",yes,P10619
ENSG00000164733,CTSB,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSB,APPS,CPSB,RECEUP",yes,P07858
ENSG00000109861,CTSC,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSC,CPPI,DPP-I,DPP1,DPPI,HMS,JP,JPD,PALS,PDON1,PLS",yes,P53634
ENSG00000117984,CTSD,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSD,CLN10,CPSD,HEL-S-130P",yes,P07339
ENSG00000174080,CTSF,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSF,CATSF,CLN13",yes,Q9UBX1
ENSG00000100448,CTSG,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSG,CATG,CG",yes,P08311
ENSG00000103811,CTSH,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSH,ACC-4,ACC-5,ACC4,ACC5,CPSB",yes,P09668
ENSG00000143387,CTSK,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSK,CTS02,CTSO,CTSO1,CTSO2,PKND,PYCD",yes,P43235
ENSG00000135047,CTSL,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSL,CATL,CTSL1,MEP",yes,P07711
ENSG00000256043,CTSO,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSO,CTSO1",yes,P43234
ENSG00000163131,CTSS,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSS,-",yes,P25774
ENSG00000136943,CTSV,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSV,CATL2,CTSL2,CTSU",yes,O60911
ENSG00000172543,CTSW,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSW,LYPN",yes,P56202
ENSG00000101160,CTSZ,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"CTSZ,CTSX",yes,Q9UBR2
ENSG00000196415,PRTN3,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protease,nan,"PRTN3,ACPA,AGP7,C-ANCA,CANCA,MBN,MBT,NP-4,NP4,P29,PR-3,PR3",yes,P24158
ENSG00000197635,DPP4,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal peptidase,nan,"DPP4,ADABP,ADCP2,CD26,DPPIV,TP103",yes,P27487
ENSG00000176978,DPP7,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal peptidase,nan,"DPP7,DPP2,DPPII,QPP",yes,Q9UHL4
ENSG00000137563,GGH,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal peptidase,nan,"GGH,GH",yes,Q92820
ENSG00000100600,LGMN,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal peptidase,nan,"LGMN,AEP,LGMN1,PRSC1",yes,Q99538
ENSG00000166340,TPP1,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal peptidase,nan,"TPP1,CLN2,GIG1,LPIC,SCAR7,TPP-1",yes,O14773
ENSG00000131238,PPT1,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal de-palmitoylation,nan,"PPT1,CLN1,INCL,PPT",yes,P50897
ENSG00000221988,PPT2,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal de-palmitoylation,nan,"PPT2,C6orf8,G14,PPT-2",yes,Q9UMR5
ENSG00000116005,PCYOX1,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal de-prenylation,nan,"PCYOX1,PCL1",yes,Q9UHG3
ENSG00000105854,PON2,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal arylesterase,nan,"PON2,-",yes,Q15165
ENSG00000239264,TXNDC5,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal protein disulfide isomerase,nan,"TXNDC5,ENDOPDI,ERP46,HCC-2,HCC2,PDIA15,STRF8,UNQ364",yes,Q8NBS9
ENSG00000216490,IFI30,Lysosomal catabolism,Lysosomal protein catabolism,Lysosomal thiol reductase,nan,"IFI30,GILT,IFI-30,IP-30,IP30",yes,P13284
ENSG00000038002,AGA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal protein deglycosidase,nan,"AGA,AGU,ASRG,GA",yes,P20933
ENSG00000171298,GAA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal glucosidase,nan,"GAA,LYAG",yes,P10253
ENSG00000102393,GLA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal galactosidase,nan,"GLA,GALA",yes,P06280
ENSG00000170266,GLB1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal galactosidase,nan,"GLB1,EBP,ELNR1,MPS4B",yes,P16278
ENSG00000104774,MAN2B1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal mannosidase,nan,"MAN2B1,LAMAN,MANB",yes,O00754
ENSG00000013288,MAN2B2,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal mannosidase,nan,"MAN2B2,-",yes,Q9Y2E5
ENSG00000109323,MANBA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal mannosidase,nan,"MANBA,MANB1",yes,O00462
ENSG00000133063,CHIT1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal chitobiase,nan,"CHIT1,CHI3,CHIT,CHITD",no,Q13231
ENSG00000117151,CTBS,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal chitobiase,nan,"CTBS,CTB",yes,Q01459
ENSG00000179163,FUCA1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal fusocidase,nan,"FUCA1,FUCA",yes,P04066
ENSG00000001036,FUCA2,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal fusocidase,nan,"FUCA2,dJ20N2.5",yes,Q9BTY2
ENSG00000196743,GM2A,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hexosaminidase,nan,"GM2A,GM2-AP,SAP-3",yes,P17900
ENSG00000213614,HEXA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hexosaminidase,nan,"HEXA,TSD",yes,P06865
ENSG00000049860,HEXB,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hexosaminidase,nan,"HEXB,ENC-1AS,HEL-248,HEL-S-111",yes,P07686
ENSG00000114378,HYAL1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hyaluronidase,nan,"HYAL1,HYAL-1,LUCA1,MPS9,NAT6",yes,Q12794
ENSG00000068001,HYAL2,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hyaluronidase,nan,"HYAL2,LUCA2",yes,Q12891
ENSG00000186792,HYAL3,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal hyaluronidase,nan,"HYAL3,HYAL-3,LUCA-3,LUCA3",yes,O43820
ENSG00000169919,GUSB,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal glucuronidase,nan,"GUSB,BG,MPS7",yes,P08236
ENSG00000127415,IDUA,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal iduronidase,nan,"IDUA,IDA,MPS1,MPSI",yes,P35475
ENSG00000204386,NEU1,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal sialidase,nan,"NEU1,NANH,NEU,SIAL1",yes,Q99519
ENSG00000204099,NEU4,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal sialidase,nan,"NEU4,-",yes,Q8WWR8
ENSG00000110013,SIAE,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal sialic acid deacetylase,nan,"SIAE,AIS6,CSE-C,CSEC,LSE,YSG2",yes,Q9HAT2
ENSG00000100994,PYGB,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal phosphorylase for glycogen catabolism,nan,"PYGB,GPBB",yes,P11216
ENSG00000173083,HPSE,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal heparinase,nan,"HPSE,HPA,HPA1,HPR1,HPSE1,HSE1",yes,Q9Y251
ENSG00000108784,NAGLU,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal heparinase,nan,"NAGLU,CMT2V,MPS-IIIB,MPS3B,NAG,UFHSD",yes,P54802
ENSG00000165102,HGSNAT,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal heparin acetyltransferase to prepare for heparin degradation,nan,"HGSNAT,HGNAT,MPS3C,RP73,TMEM76",yes,Q68CP4
ENSG00000181523,SGSH,Lysosomal catabolism,Lysosomal carbohydrate catabolism,Lysosomal heparin sulfatase,nan,"SGSH,HSS,MPS3A,SFMD",yes,P51688
ENSG00000163686,ABHD6,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal lipase,nan,"ABHD6,-",yes,Q9BV23
ENSG00000164535,DAGLB,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal lipase,nan,"DAGLB,DAGLBETA,KCCR13L",yes,Q8NCG7
ENSG00000107798,LIPA,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal lipase,nan,"LIPA,CESD,LAL",yes,P38571
ENSG00000069764,PLA2G10,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLA2G10,GXPLA2,GXSPLA2,SPLA2,sPLA2-X",no,O15496
ENSG00000103066,PLA2G15,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLA2G15,ACS,GXVPLA2,LLPL,LPLA2,LYPLA3",yes,Q8NCC3
ENSG00000188089,PLA2G4E,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLA2G4E,-",yes,Q3MJ16
ENSG00000127472,PLA2G5,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLA2G5,FRFB,GV-PLA2,PLA2-10,hVPLA(2)",yes,P39877
ENSG00000121316,PLBD1,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLBD1,-",yes,Q6P4A8
ENSG00000151176,PLBD2,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLBD2,P76",yes,Q8NHP8
ENSG00000075651,PLD1,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLD1,CVDD",yes,Q13393
ENSG00000105223,PLD3,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PLD3,AD19,HU-K4,HUK4,SCA46",yes,Q8IV08
ENSG00000117592,PRDX6,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"PRDX6,1-Cys,AOP2,HEL-S-128m,NSGPx,PRX,aiPLA2,p29",yes,P30041
ENSG00000112293,GPLD1,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal phospholipase,nan,"GPLD1,GPIPLD,GPIPLDM,PIGPLD,PIGPLD1,PLD",yes,P80108
ENSG00000138744,NAAA,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal fatty acid amidase,nan,"NAAA,ASAHL,PLT",yes,Q02083
ENSG00000104763,ASAH1,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Lysosomal ceramidase,"ASAH1,AC,ACDase,ASAH,PHP,PHP32,SMAPME",yes,Q13510
ENSG00000054983,GALC,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Lysosomal ceramidase,"GALC,-",yes,P54803
ENSG00000177628,GBA,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Lysosomal ceramidase,"GBA,GBA1,GCB,GLUC",yes,P04062
ENSG00000198951,NAGA,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Lysosomal glycosyl deacetylase,"NAGA,D22S674,GALB",yes,P17050
ENSG00000166311,SMPD1,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Converts sphingomyelin to ceramide,"SMPD1,ASM,ASMASE,NPD",yes,P17405
ENSG00000063176,SPHK2,Lysosomal catabolism,Lysosomal lipid catabolism,Lysosomal sphingomyelin/ceramide metabolism,Phosphorylates sphingomyelin,"SPHK2,SK 2,SK-2,SPK 2,SPK-2",yes,Q9NRA0
ENSG00000134575,ACP2,Lysosomal catabolism,Lysosomal phosphatase,nan,nan,"ACP2,LAP",yes,P11117
ENSG00000014257,ACPP,Lysosomal catabolism,Lysosomal phosphatase,nan,nan,"ACP3,5'-NT,ACP-3,ACPP,TM-PAP",yes,P15309
ENSG00000142513,ACPT,Lysosomal catabolism,Lysosomal phosphatase,nan,nan,"ACP4,ACPT,AI1J",yes,Q9BZG2
ENSG00000102575,ACP5,Lysosomal catabolism,Lysosomal phosphatase,nan,nan,"ACP5,HPAP,TRACP5a,TRACP5b,TRAP,TrATPase",yes,P13686
ENSG00000100299,ARSA,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"ARSA,ASA,MLD",yes,P15289
ENSG00000113273,ARSB,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"ARSB,ASB,G4S,MPS6",yes,P15848
ENSG00000006756,ARSD,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"ARSD,ASD",yes,P51689
ENSG00000141337,ARSG,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"ARSG,USH4",yes,Q96EG1
ENSG00000141012,GALNS,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"GALNS,GALNAC6S,GAS,GalN6S,MPS4A",yes,P34059
ENSG00000135677,GNS,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"GNS,G6S",yes,P15586
ENSG00000010404,IDS,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"IDS,ID2S,MPS2,SIDS",yes,P22304
ENSG00000101846,STS,Lysosomal catabolism,Lysosomal sulfatase,nan,nan,"STS,ARSC,ARSC1,ASC,ES,SSDD,XLI",yes,P08842
ENSG00000105612,DNASE2,Lysosomal catabolism,Lysosomal nuclease,nan,nan,"DNASE2,DNASE2A,DNL,DNL2",yes,O00115
ENSG00000137976,DNASE2B,Lysosomal catabolism,Lysosomal nuclease,nan,nan,"DNASE2B,DLAD",yes,Q8WZ79
ENSG00000030582,GRN,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,nan,"GRN,CLN11,GEP,GP88,PCDGF,PEPI,PGRN",yes,P28799
ENSG00000106460,TMEM106B,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,nan,"TMEM106B,HLD16",yes,Q9NUM4
ENSG00000127419,TMEM175,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,nan,"TMEM175,hTMEM175",yes,Q9BSA9
ENSG00000103249,CLCN7,Lysosomal catabolism,Regulation of lysosomal environment,Lysosomal acidification,nan,"CLCN7,HOD,CLC7,CLC-7,OPTA2,OPTB4,PPP1R63",yes,P51798
ENSG00000078081,LAMP3,Lysosomal catabolism,none,none,none,none,yes,none
ENSG00000254647,INS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream activator of IRS1/2/4,"INS,IDDM,IDDM1,IDDM2,ILPR,IRDN,MODY10,PNDM4",no,P01308
ENSG00000017427,IGF1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream activator of IRS1/2/4,"IGF1,IGF,IGF-I,IGFI,MGF",yes,P05019
ENSG00000140443,IGF1R,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream activator of IRS1/2/4,"IGF1R,CD221,IGFIR,IGFR,JTK13",yes,P08069
ENSG00000141510,TP53,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream activator of IRS1/2/4,"TP53,BCC7,BMFS5,LFS1,P53,TRP53",yes,P04637
ENSG00000146674,IGFBP3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream suppressor of IRS1/2/4,"IGFBP3,BP-53,IBP3",yes,P17936
ENSG00000163558,PRKCI,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Upstream suppressor of IRS1/2/4,"PRKCI,DXS1179E,PKCI,nPKC-iota",yes,P41743
ENSG00000169047,IRS1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex activator,"IRS1,HIRS-1",yes,P35568
ENSG00000185950,IRS2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex activator,"IRS2,IRS-2",yes,Q9Y4H2
ENSG00000133124,IRS4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex activator,"IRS4,CHNG9,IRS-4,PY160",yes,O14654
ENSG00000121879,PIK3CA,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex component,"PIK3CA,CLAPO,CLOVE,CWS5,MCAP,MCM,MCMTC,PI3K,PI3K-alpha,p110-alpha",yes,P42336
ENSG00000051382,PIK3CB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex component,"PIK3CB,P110BETA,PI3K,PI3KBETA,PIK3C1",yes,P42338
ENSG00000171608,PIK3CD,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex component,"PIK3CD,APDS,IMD14,P110DELTA,PI3K,p110D",yes,O00329
ENSG00000145675,PIK3R1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex component,"PIK3R1,AGM7,GRB1,IMD36,p85,p85-ALPHA",yes,P27986
ENSG00000105647,PIK3R2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PI3K complex component,"PIK3R2,MPPH,MPPH1,P85B,p85,p85-BETA",yes,O00459
ENSG00000171862,PTEN,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,PIP3 dephosphorylation,"PTEN,10q23del,BZS,CWS1,DEC,GLM2,MHAM,MMAC1,PTEN1,PTENbeta,TEP1",yes,P60484
ENSG00000140992,PDPK1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, non-mTORC2 complex component","PDPK1,PDK1,PDPK2,PDPK2P,PRO0461",yes,O15530
ENSG00000113520,IL4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, non-mTORC2 complex component","IL4,BCGF-1,BCGF1,BSF-1,BSF1,IL-4",no,P05112
ENSG00000169194,IL13,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, non-mTORC2 complex component","IL13,IL-13,P600",yes,P35225
ENSG00000198793,MTOR,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","MTOR,FRAP,FRAP1,FRAP2,RAFT1,RAPT1,SKS",yes,P42345
ENSG00000164327,RICTOR,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","RICTOR,PIA; AVO3; hAVO3",yes,Q6R327
ENSG00000167965,MLST8,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","MLST8,GBL,GbetaL,LST8,POP3,WAT1",yes,Q9BVC4
ENSG00000119487,MAPKAP1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","MAPKAP1,MIP1; SIN1; JC310; SIN1b; SIN1g",yes,Q9BPZ7
ENSG00000155792,DEPTOR,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","DEPTOR,DEP.6,DEPDC6",yes,Q8TB45
ENSG00000101407,TTI1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","TTI1,smg-10; KIAA0406",yes,O43156
ENSG00000100726,TELO2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,"AKT1 activator, mTORC2 complex component","TELO2,CLK2,TEL2,YHFS",yes,Q9Y4R8
ENSG00000142208,AKT1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,TSC complex deactivator,"AKT1,AKT,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA",yes,P31749
ENSG00000077463,SIRT6,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Insulin signaling pathway,Miscellaneous suppressor of IGF signaling,"SIRT6,SIR2L6",yes,Q8N6T7
ENSG00000155876,RRAGA,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex component,"RRAGA,FIP-1,FIP1,RAGA",yes,Q7L523
ENSG00000083750,RRAGB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex component,"RRAGB,RAGB,bA465E19.1",yes,Q5VZM2
ENSG00000116954,RRAGC,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex component,"RRAGC,GTR2,RAGC,TIB929",yes,Q9HB90
ENSG00000025039,RRAGD,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex component,"RRAGD,RAGD,bA11D8.2.1",yes,Q9NQL2
ENSG00000133706,LARS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"LARS1,HSPC192,ILFS1,LARS,LEURS,LEUS,LFIS,LRS,PIG44,RNTLS,hr025Cl",yes,Q9P2J5
ENSG00000154803,FLCN,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"FLCN,BHD,DENND8B,FLCL",yes,Q8NFG4
ENSG00000217128,FNIP1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"FNIP1,-",yes,Q8TF40
ENSG00000077585,GPR137B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"GPR137B,TM7SF1",yes,O60478
ENSG00000176641,RNF152,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"RNF152,-",yes,Q8N8N0
ENSG00000130147,SH3BP4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"SH3BP4,BOG25,TTP",yes,Q9P0V3
ENSG00000007047,MARK4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,RAGA/B-RAGC/D complex modulator,"MARK4,MARK4L,MARK4S,MARKL1,MARKL1L,PAR-1D",yes,Q96L34
ENSG00000149357,LAMTOR1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex component,"LAMTOR1,C11orf59,PDRO,Ragulator1,p18,p27RF-Rho",yes,Q6IAA8
ENSG00000116586,LAMTOR2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex component,"LAMTOR2,ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14",yes,Q9Y2Q5
ENSG00000109270,LAMTOR3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex component,"LAMTOR3,MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3",yes,Q9UHA4
ENSG00000188186,LAMTOR4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex component,"LAMTOR4,C7orf59",yes,Q0VGL1
ENSG00000134248,LAMTOR5,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex component,"LAMTOR5,HBXIP,XIP",yes,O43504
ENSG00000111276,CDKN1B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Ragulator complex modulator,"CDKN1B,CDKN4,KIP1,MEN1B,MEN4,P27KIP1",yes,P46527
ENSG00000114388,NPRL2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR1 complex component,"NPRL2,FFEVF2,NPR2,NPR2L,TUSC4",yes,Q8WTW4
ENSG00000103148,NPRL3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR1 complex component,"NPRL3,C16orf35,CGTHBA,FFEVF3,HS-40,MARE,NPR3,RMD11",yes,Q12980
ENSG00000100150,DEPDC5,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR1 complex component,"DEPDC5,DEP.5,FFEVF,FFEVF1",yes,O75140
ENSG00000164603,BMT2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR1 complex modulator,"BMT2,C7orf60,SAMTOR",yes,Q1RMZ1
ENSG00000157020,SEC13,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex component,"SEC13,D3S1231E,SEC13L1,SEC13R,npp-20",yes,P55735
ENSG00000085415,SEH1L,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex component,"SEH1L,SEC13L,SEH1A,SEH1B,Seh1",yes,Q96EE3
ENSG00000103091,WDR59,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex component,"WDR59,CDW12,FP977,p90-120",yes,Q6PJI9
ENSG00000127580,WDR24,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex component,"WDR24,C16orf21,JFP7",yes,Q96S15
ENSG00000164654,MIOS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex component,"MIOS,MIO,Sea4,Yulink",yes,Q9NXC5
ENSG00000152700,SAR1B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex modulator,"SAR1B,ANDD,CMRD,GTBPB,SARA2",yes,Q9Y6B6
ENSG00000080546,SESN1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex modulator,"SESN1,PA26,SEST1",yes,Q9Y6P5
ENSG00000130766,SESN2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex modulator,"SESN2,HI95,SES2,SEST2",yes,P58004
ENSG00000149212,SESN3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,GATOR2 complex modulator,"SESN3,SEST3",yes,P58005
ENSG00000239282,GATSL3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Castor complex component,"CASTOR1,GATSL3",yes,Q8WTX7
ENSG00000274070,GATSL2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Castor complex component,"CASTOR2,GATSL1,GATSL2",yes,A6NHX0
ENSG00000118162,KPTN,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,KICSTOR complex component,"KPTN,2E4,KICS4,MRT41",yes,Q9Y664
ENSG00000111203,ITFG2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,KICSTOR complex component,"ITFG2,KICS3,FGGAP1,MDS028",yes,Q969R8
ENSG00000174206,C12orf66,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,KICSTOR complex component,"KICS2,C12orf66",no,Q96MD2
ENSG00000198198,SZT2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,KICSTOR complex component,"SZT2,DEE18,KICS1,SZT2A,SZT2B,EIEE18,C1orf84,KIAA0467",yes,Q5T011
ENSG00000033627,ATP6V0A1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0A1,ATP6N1,ATP6N1A,Stv1,VPP1,Vph1,a1",yes,Q93050
ENSG00000185344,ATP6V0A2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0A2,A2,ARCL,ARCL2A,ATP6A2,ATP6N1D,J6B7,RTF,STV1,TJ6,TJ6M,TJ6S,VPH1,WSS",yes,Q9Y487
ENSG00000110719,TCIRG1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"TCIRG1,ATP6N1C,ATP6V0A3,Atp6i,OC-116kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3",yes,Q13488
ENSG00000105929,ATP6V0A4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0A4,A4,ATP6N1B,ATP6N2,DRTA3,RDRTA2,RTA1C,RTADR,STV1,VPH1,VPP2",yes,Q9HBG4
ENSG00000117410,ATP6V0B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0B,ATP6F,HATPL,VMA16",yes,Q99437
ENSG00000185883,ATP6V0C,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0C,ATP6C,ATP6L,ATPL,VATL,VPPC,Vma3",yes,P27449
ENSG00000159720,ATP6V0D1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0D1,ATP6D,ATP6DV,P39,VATX,VMA6,VPATPD",yes,P61421
ENSG00000147614,ATP6V0D2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0D2,ATP6D2,VMA6",no,Q8N8Y2
ENSG00000113732,ATP6V0E1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0E1,ATP6H,ATP6V0E,M9.2,Vma21,Vma21p",yes,O15342
ENSG00000171130,ATP6V0E2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V0 lysosomal v-ATPase proton pump component,"ATP6V0E2,ATP6V0E2L,C7orf32",yes,Q8NHE4
ENSG00000114573,ATP6V1A,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1A,ARCL2D,ATP6A1,ATP6V1A1,HO68,IECEE3,VA68,VPP2,Vma1",yes,P38606
ENSG00000116039,ATP6V1B1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1B1,ATP6B1,DRTA2,RTA1B,VATB,VMA2,VPP3",yes,P15313
ENSG00000147416,ATP6V1B2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1B2,ATP6B1B2,ATP6B2,DOOD,HO57,VATB,VPP3,Vma2,ZLS2",yes,P21281
ENSG00000155097,ATP6V1C1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1C1,ATP6C,ATP6D,VATC,Vma5",yes,P21283
ENSG00000143882,ATP6V1C2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1C2,ATP6C2,VMA5",yes,Q8NEY4
ENSG00000100554,ATP6V1D,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1D,ATP6M,VATD,VMA8",yes,Q9Y5K8
ENSG00000131100,ATP6V1E1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1E1,ARCL2C,ATP6E,ATP6E2,ATP6V1E,P31,Vma4",yes,P36543
ENSG00000250565,ATP6V1E2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1E2,ATP6E1,ATP6EL2,ATP6V1EL2,VMA4",yes,Q96A05
ENSG00000128524,ATP6V1F,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1F,ATP6S14,VATF,Vma7",yes,Q16864
ENSG00000136888,ATP6V1G1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1G1,ATP6G,ATP6G1,ATP6GL,ATP6J,Vma10",yes,O75348
ENSG00000213760,ATP6V1G2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1G2,ATP6G,ATP6G2,NG38,VMA10",yes,O95670
ENSG00000151418,ATP6V1G3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1G3,ATP6G3,Vma10",no,Q96LB4
ENSG00000047249,ATP6V1H,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,V1 lysosomal v-ATPase proton pump component,"ATP6V1H,CGI-11,MSTP042,NBP1,SFD,SFDalpha,SFDbeta,VMA13",yes,Q9UI12
ENSG00000071553,ATP6AP1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Regulator of the lysosomal v-ATPase proton pump,"ATP6AP1,16A,ATP6IP1,ATP6S1,Ac45,CF2,VATPS1,XAP-3,XAP3",yes,Q15904
ENSG00000182220,ATP6AP2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,Regulator of the lysosomal v-ATPase proton pump,"ATP6AP2,APT6M8-9,ATP6IP2,ATP6M8-9,CDG2R,ELDF10,HT028,M8-9,MRXE,MRXSH,MSTP009,PRR,RENR,XMRE,XPDS",yes,O75787
ENSG00000177058,SLC38A9,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"SLC38A9,URLC11",yes,Q8NBW4
ENSG00000148672,GLUD1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"GLUD1,GDH,GDH1,GLUD",yes,P00367
ENSG00000099910,KLHL22,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"KLHL22,KELCHL",yes,Q53GT1
ENSG00000100393,EP300,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"EP300,KAT3B,MKHK2,RSTS2,p300",yes,Q09472
ENSG00000174697,LEP,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"LEP,LEPD,OB,OBS",yes,P41159
ENSG00000116678,LEPR,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Nutrient sensing,MTORC1 complex modulator by metabolite balance,"LEPR,CD295,LEP-R,LEPRD,OB-R,OBR",yes,P48357
ENSG00000132356,PRKAA1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAA1,AMPK,AMPKa1",yes,Q13131
ENSG00000162409,PRKAA2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAA2,AMPK,AMPK2,AMPKa2,PRKAA",yes,P54646
ENSG00000111725,PRKAB1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAB1,AMPK,HAMPKb",yes,Q9Y478
ENSG00000131791,PRKAB2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAB2,-",yes,O43741
ENSG00000181929,PRKAG1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAG1,AMPKG",yes,P54619
ENSG00000106617,PRKAG2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAG2,AAKG,AAKG2,CMH6,H91620p,WPWS",yes,Q9UGJ0
ENSG00000115592,PRKAG3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex component,"PRKAG3,AMPKG3",yes,Q9UGI9
ENSG00000072062,PRKACA,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKACA,PKACA,PPNAD4",yes,P17612
ENSG00000142875,PRKACB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKACB,PKA C-beta,PKACB",yes,P22694
ENSG00000165059,PRKACG,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKACG,BDPLT19,KAPG,PKACg",yes,P22612
ENSG00000108946,PRKAR1A,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKAR1A,ACRDYS1,ADOHR,CAR,CNC,CNC1,PKR1,PPNAD1,PRKAR1,TSE1",yes,P10644
ENSG00000188191,PRKAR1B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKAR1B,PRKAR1",yes,P31321
ENSG00000114302,PRKAR2A,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKAR2A,PKR2,PRKAR2",yes,P13861
ENSG00000005249,PRKAR2B,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- PKA complex component,"PRKAR2B,PRKAR2,RII-BETA",yes,P31323
ENSG00000213341,CHUK,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- IKK complex component,"CHUK,IKBKA,IKK-alpha,IKK1,IKKA,NFKBIKA,TCF16",yes,O15111
ENSG00000104365,IKBKB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- IKK complex component,"IKBKB,IKK-beta,IKK2,IKKB,IMD15,IMD15A,IMD15B,NFKBIKB",yes,O14920
ENSG00000269335,IKBKG,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- IKK complex component,"IKBKG,AMCBX1,EDAID1,FIP-3,FIP3,Fip3p,IKK-gamma,IKKAP1,IKKG,IMD33,IP,IP1,IP2,IPD2,NEMO,ZC2HC9",yes,Q9Y6K9
ENSG00000135341,MAP3K7,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation- IKK complex activator,"MAP3K7,CSCF,FMD2,MEKK7,TAK1,TGF1a",yes,O43318
ENSG00000118046,STK11,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation,"STK11,LKB1,PJS,hLKB1",yes,Q15831
ENSG00000135932,CAB39,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation,"CAB39,CGI-66,MO25",yes,Q9Y376
ENSG00000266173,STRADA,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation,"STRADA,LYK5,NY-BR-96,PMSE,STRAD,STRAD alpha,Stlk",yes,Q7RTN6
ENSG00000110931,CAMKK2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex modulator by phosphorylation,"CAMKK2,CAMKK,CAMKKB",yes,Q96RR4
ENSG00000130726,TRIM28,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex ubiquitination,"TRIM28,KAP1,PPP1R157,RNF96,TF1B,TIF1B",yes,Q13263
ENSG00000221867,MAGEA3,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex ubiquitination,"MAGEA3,CT1.3,HIP8,HYPD,MAGE3,MAGEA6",yes,P43357
ENSG00000197172,MAGEA6,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex ubiquitination,"MAGEA6,CT1.6,MAGE-3b,MAGE3B,MAGE6",yes,P43360
ENSG00000198876,DCAF12,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex ubiquitination,"DCAF12,CT102,KIAA1892,TCC52,WDR40A",yes,Q5T6F0
ENSG00000056736,IL17RB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, direct",AMPK complex ubiquitination,"IL17RB,CRL4,EVI27,IL17BR,IL17RH1",yes,Q9NRM6
ENSG00000149311,ATM,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream",AMPK complex modulator by metabolite balance,"ATM,AT1,ATA,ATC,ATD,ATDC,ATE,TEL1,TELO1",yes,Q13315
ENSG00000163565,IFI16,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream",AMPK complex modulator by metabolite balance,"IFI16,IFNGIP1,PYHIN2",yes,Q16666
ENSG00000147649,MTDH,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream",AMPK complex modulator by metabolite balance,"MTDH,3D3,AEG-1,AEG1,LYRIC,LYRIC/3D3",yes,Q86UE4
ENSG00000150995,ITPR1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream",AMPK complex modulator by Ca2+ signaling,"ITPR1,ACV,CLA4,INSP3R1,IP3R,IP3R1,PPP1R94,SCA15,SCA16,SCA29",yes,Q14643
ENSG00000133112,TPT1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream","AMPK complex modulator, miscellaneous","TPT1,HRF,TCTP,p02,p23",yes,P13693
ENSG00000160469,BRSK1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream","AMPK complex modulator, miscellaneous","BRSK1,hSAD1",yes,Q8TDC3
ENSG00000174672,BRSK2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream","AMPK signaling pathway, upstream","AMPK complex modulator, miscellaneous","BRSK2,C11orf7,PEN11B,SAD1,SADA,STK29",yes,Q8IWQ3
ENSG00000174775,HRAS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"HRAS,C-BAS/HAS,C-H-RAS,C-HA-RAS1,CTLO,H-RASIDX,HAMSV,HRAS1,RASH1,p21ras",yes,P01112
ENSG00000133703,KRAS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"KRAS,'C-K-RAS,C-K-RAS,CFC2,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,K-Ras,K-Ras 2,KI-RAS,KRAS1,KRAS2,NS,NS3,OES,RALD,RASK2,c-Ki-ras,c-Ki-ras2",yes,P01116
ENSG00000213281,NRAS,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"NRAS,ALPS4,CMNS,N-ras,NCMS,NRAS1,NS6",yes,P01111
ENSG00000132155,RAF1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"RAF1,CMD1NN,CRAF,NS5,Raf-1,c-Raf",yes,P04049
ENSG00000169032,MAP2K1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"MAP2K1,CFC3,MAPKK1,MEK1,MEL,MKK1,PRKMK1",yes,Q02750
ENSG00000126934,MAP2K2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"MAP2K2,CFC4,MAPKK2,MEK2,MKK2,PRKMK2",yes,P36507
ENSG00000100030,MAPK1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"MAPK1,ERK,ERK-2,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK",yes,P28482
ENSG00000113712,CSNK1A1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",MAPK1 signaling pathway,nan,"CSNK1A1,CK1,CK1a,CKIa,HEL-S-77p,HLCDGP1,PRO2975",yes,P48729
ENSG00000100644,HIF1A,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Hypoxia signaling pathway,nan,"HIF1A,HIF-1-alpha,HIF-1A,HIF-1alpha,HIF1,HIF1-ALPHA,MOP1,PASD8,bHLHe78",yes,Q16665
ENSG00000168209,DDIT4,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Hypoxia signaling pathway,nan,"DDIT4,Dig2,REDD-1,REDD1",yes,Q9NX09
ENSG00000172216,CEBPB,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Hypoxia signaling pathway,nan,"CEBPB,C/EBP-beta,IL6DBP,NF-IL6,TCF5",yes,P17676
ENSG00000165699,TSC1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"TSC1,LAM,TSC",yes,Q92574
ENSG00000103197,TSC2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"TSC2,LAM,PPP1R160,TSC4",yes,P49815
ENSG00000145979,TBC1D7,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"TBC1D7,MGCPH,PIG51,TBC7",no,Q9P0N9
ENSG00000103657,HERC1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"HERC1,MDFPMR,p532,p619",yes,Q15751
ENSG00000102030,NAA10,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"NAA10,ARD1,ARD1A,ARD1P,DXS707,MCOPS1,NATD,OGDNS,TE2,hARD1",yes,P41227
ENSG00000005810,MYCBP2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"MYCBP2,Myc-bp2,PAM,PHR1,Phr",yes,O75592
ENSG00000159363,ATP13A2,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"ATP13A2,CLN12,HSA9947,KRPPD,PARK9,SPG78",yes,Q9NQ11
ENSG00000132718,SYT11,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",mTORC1 signal integration,nan,"SYT11,SYT12,sytXI",yes,Q9BT88
ENSG00000224051,CPTP,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Miscellaneous mTORC1 regulation,nan,"CPTP,GLTPD1",yes,Q5TA50
ENSG00000007062,PROM1,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Miscellaneous mTORC1 regulation,nan,"PROM1,AC133,CD133,CORD12,MCDR2,MSTP061,PROML1,RP41,STGD4",yes,O43490
ENSG00000113595,TRIM23,Pre-initiation autophagy signaling,"mTORC1 pathway, upstream",Miscellaneous mTORC1 regulation,nan,"TRIM23,ARD1,ARFD1,RNF46",yes,P36406
ENSG00000141564,RPTOR,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",mTORC1 complex component,nan,"RPTOR,KOG1,Mip1",yes,Q8N122
ENSG00000204673,AKT1S1,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",mTORC1 complex component,nan,"AKT1S1,Lobe,PRAS40",yes,Q96B36
ENSG00000106615,RHEB,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"RHEB,RHEB2",yes,Q15382
ENSG00000035664,DAPK2,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"DAPK2,DRP-1,DRP1",yes,Q9UIK4
ENSG00000109670,FBXW7,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"FBXW7,AGO,CDC4,FBW6,FBW7,FBX30,FBXO30,FBXW6,SEL-10,SEL10,hAgo,hCdc4",yes,Q969H0
ENSG00000108061,SHOC2,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"SHOC2,NSLH1,SIAA0862,SOC2,SUR8",yes,Q9UQ13
ENSG00000163507,KIAA1524,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"CIP2A,KIAA1524,p90",yes,Q8TCG1
ENSG00000183735,TBK1,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"TBK1,FTDALS4,IIAE8,NAK,T2K",yes,Q9UHD2
ENSG00000087586,AURKA,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"AURKA,AIK,ARK1,AURA,BTAK,PPP1R47,STK15,STK6,STK7",yes,O14965
ENSG00000111087,GLI1,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"GLI1,GLI,PAPA8,PPD1",yes,P08151
ENSG00000118503,TNFAIP3,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"TNFAIP3,A20,AISBL,OTUD7C,TNFA1P2",yes,P21580
ENSG00000095970,TREM2,Pre-initiation autophagy signaling,"mTORC1 pathway, direct",Modulator of mTORC1 activity,nan,"TREM2,PLOSL2,TREM-2,Trem2a,Trem2b,Trem2c",yes,Q9NZC2
ENSG00000170312,CDK1,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,Phosphorylates mTORC1 targets,nan,"CDK1,CDC2,CDC28A,P34CDC2",yes,P06493
ENSG00000134057,CCNB1,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,Phosphorylates mTORC1 targets,nan,"CCNB1,CCNB",yes,P14635
ENSG00000135914,HTR2B,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,Phosphorylates mTORC1 targets,nan,"HTR2B,5-HT(2B),5-HT-2B,5-HT2B",yes,P41595
ENSG00000108691,CCL2,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,Inhibition of apoptosis by caspase-8 inhibition,nan,"CCL2,GDCF-2,HC11,HSMCR30,MCAF,MCP-1,MCP1,SCYA2,SMC-CF",yes,P13500
ENSG00000136244,IL6,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,Inhibition of apoptosis by caspase-8 inhibition,nan,"IL6,BSF-2,BSF2,CDF,HGF,HSF,IFN-beta-2,IFNB2,IL-6",yes,P05231
ENSG00000112977,DAP,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,mTORC1 independent autophagy inhibition,nan,"DAP,-",yes,P51397
ENSG00000078237,TIGAR,Pre-initiation autophagy signaling,Miscellaneous autophagy signaling,General antioxidant,nan,"TIGAR,C12orf5,FR2BP",yes,Q9NQ88
ENSG00000065135,GNAI3,Pre-initiation autophagy signaling,Specific function in pre-initiation autophagy signaling unknown,nan,nan,"GNAI3,87U6,ARCND1",yes,P08754
ENSG00000171700,RGS19,Pre-initiation autophagy signaling,Specific function in pre-initiation autophagy signaling unknown,nan,nan,"RGS19,GAIP,RGSGAIP",yes,P49795
ENSG00000160360,GPSM1,Pre-initiation autophagy signaling,Specific function in pre-initiation autophagy signaling unknown,nan,nan,"GPSM1,AGS3",yes,Q86YR5
ENSG00000115355,CCDC88A,Pre-initiation autophagy signaling,Specific function in pre-initiation autophagy signaling unknown,nan,nan,"CCDC88A,APE,GIRDIN,GIV,GRDN,HkRP1,KIAA1212,PEHO,PEHOL",yes,Q3V6T2