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"https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E10,/0/default.jpg", "100": "https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E100,/0/default.jpg", "1200": "https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E1200,/0/default.jpg", "250": "https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E250,/0/default.jpg", "50": "https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E50,/0/default.jpg", "750": "https://zenodo.org/api/iiif/record:13536259:Melchjorsen%20et%20al.%20-%202009%20-%20Differential%20Regulation%20of%20the%20OASL%20and%20OAS1%20Genes.pdf/full/%5E750,/0/default.jpg" }, "versions": "https://zenodo.org/api/records/13536259/versions" }, "media_files": { "enabled": false }, "metadata": { "creators": [ { "person_or_org": { "family_name": "Melchjorsen", "given_name": "Jesper", "name": "Melchjorsen, Jesper", "type": "personal" } }, { "person_or_org": { "family_name": "Kristiansen", "given_name": "Helle", "name": "Kristiansen, Helle", "type": "personal" } }, { "person_or_org": { "family_name": "Christiansen", "given_name": "Rune", "name": "Christiansen, Rune", "type": "personal" } }, { "person_or_org": { "family_name": "Rintahaka", "given_name": "Johanna", "name": "Rintahaka, Johanna", "type": "personal" } }, { "person_or_org": { "family_name": "Matikainen", "given_name": "Sampsa", "name": "Matikainen, Sampsa", "type": "personal" } }, { "person_or_org": { "family_name": "Paludan", "given_name": "S\u00f8ren", "name": "Paludan, S\u00f8ren", "type": "personal" } }, { "person_or_org": { "family_name": "Hartmann", "given_name": "Rune", "name": "Hartmann, Rune", "type": "personal" } } ], "description": "(Uploaded by Plazi for the Bat Literature Project) The 2'-5' oligoadenylate synthetase (OAS) family consist of three genes encoding active OAS enzymes (OAS1-3) and an OAS-Like (OASL) gene encoding an inactive protein. The transcription of all four members of this family is actively induced by interferon (IFN), but so far no attempt to systematically analyze the expression of these genes during viral infection has been made. We analyzed the expression of the human OAS1 and OASL genes in response to infection with Sendai virus or Influenza A virus. Surprisingly, we found a marked difference in the expression pattern of these genes. Our data showed that the OASL gene is rapidly induced in response to viral infection and that this induction is mediated by IFN regulatory factor 3 (IRF-3). In contrast to the OASL gene, the induction of the OAS1 gene by virus infection was lower, and did require a functional type I IFN response. The pronounced difference in gene regulation between the OAS1 and OASL genes agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein. Furthermore, the behavior of the OASL gene is consistent with the behavior of an antiviral gene.", "identifiers": [ { "identifier": "hash://md5/d769640e84936b051f5fc1b38d1196f7", "scheme": "url" }, { "identifier": "urn:lsid:zotero.org:groups:5435545:items:QMYRFFXM", "scheme": "urn" }, { "identifier": "10.1089/jir.2008.0050", "scheme": "doi" } ], "publication_date": "2009", "publisher": "Zenodo", "related_identifiers": [ { "identifier": "hash://md5/d769640e84936b051f5fc1b38d1196f7", "relation_type": { "id": "hasversion", "title": { "de": "Hat versionierte Instanz", "en": "Has version" } }, "scheme": "url" }, { "identifier": "hash://sha256/f088bee758c76252bf1d24802f5f244846fc287c056463b333743deed021d31e", "relation_type": { "id": "hasversion", "title": { "de": "Hat versionierte Instanz", "en": "Has version" } }, "scheme": "url" }, { "identifier": "zotero://select/groups/5435545/items/QMYRFFXM", "relation_type": { "id": "isderivedfrom", "title": { "de": "Wird abgeleitet von", "en": "Is derived from" } }, "scheme": "url" }, { "identifier": "https://zotero.org/groups/5435545/items/QMYRFFXM", "relation_type": { "id": "isderivedfrom", "title": { "de": "Wird abgeleitet von", "en": "Is derived from" } }, "scheme": "url" }, { "identifier": "https://linker.bio/cut:hash://md5/47dcdd7ec1a1ddc1f6bc36dbb711914f!/b287356-290152", "relation_type": { "id": "isderivedfrom", "title": { "de": "Wird abgeleitet von", "en": "Is derived from" } }, "scheme": "url" }, { "identifier": "hash://md5/0157e8ec3f1f8eb877e7b6cd6fde26bc", "relation_type": { "id": "ispartof", "title": { "de": "Ist Teil von", "en": "Is part of" } }, "scheme": "url" }, { "identifier": "10.5281/zenodo.1410543", "relation_type": { "id": "iscompiledby", "title": { "de": "Kompiliert durch", "en": "Is compiled by" } }, "resource_type": { "id": "software", "title": { "de": "Software", "en": "Software" } }, "scheme": "doi" } ], "resource_type": { "id": "publication-article", "title": { "de": "Zeitschriftenartikel", "en": "Journal article" } }, "subjects": [ { "subject": "Biodiversity" }, { "subject": "Mammalia" }, { "subject": "Chiroptera" }, { "subject": "Chordata" }, { "subject": "Animalia" }, { "subject": "bats" }, { "subject": "bat" } ], "title": "Differential Regulation of the OASL and OAS1 Genes in Response to Viral Infections" }, "parent": { "access": { "owned_by": { "user": "7292" }, "settings": { "accept_conditions_text": null, "allow_guest_requests": false, "allow_user_requests": false, "secret_link_expiration": 0 } }, "communities": { "default": "23bc63d8-1a49-4a20-9519-fb3a3e78f2b4", "entries": [ { "access": { "member_policy": "open", "members_visibility": "public", "record_submission_policy": "open", "review_policy": "open", "visibility": "public" }, "children": { "allow": false }, "created": "2024-05-09T16:51:13.649165+00:00", "custom_fields": {}, "deletion_status": { "is_deleted": false, "status": "P" }, "id": "23bc63d8-1a49-4a20-9519-fb3a3e78f2b4", "links": {}, "metadata": { "description": "Plazi and the GBatNet Bat Eco-Interactions Working Group are compiling the Bat Literature Corpus, an actively managed, digital, versioned, and citable collection of bat research literature and associated metadata compiled from existing literature.", "title": "Bat Literature Project", "type": { "id": "project" }, "website": "https://batlit.org/" }, "parent": { "access": { "member_policy": "open", "members_visibility": "public", "record_submission_policy": "open", "review_policy": "open", "visibility": "public" }, "children": { "allow": true }, "created": "2013-11-11T14:14:18+00:00", "custom_fields": {}, "deletion_status": { "is_deleted": false, "status": "P" }, "id": "c529f97d-f8cb-4c13-a439-9e36891694c2", "links": {}, "metadata": { "curation_policy": "
    \n
  1. If an uploaded document has an existing DOI, it will be kept. If there is no DOI, a Zenodo DOI will be minted for the item.
    2. \n
  2. Items with Open Access remain Open Access.
    3. \n
  3. Items with closed access remain closed. If they are published on 31.12.1999 or earlier, they are made accessible for reading. Please consult your national copyright law for conditions of reuse.
    4. \n
  4. To upload publications, please contact info@plazi.org.
    5. \n
", "description": "A community to share publications related to bio-systematics.", "funding": [ { "funder": { "id": "051z6e826" } } ], "organizations": [ { "name": "Plazi" } ], "page": "

The Biodiversity Literature Repository (BLR) is to share publications related to bio-systematics. The goal is to provide

\n
    \n
  1. open access to publications cited in publications or in combination with scientific names
    2. \n
  2. open access FAIR data with focus on taxon treatments and figures liberated from publications
    3. \n
  3. a digital object identifier (DOI) to enable citation of the publications and data including direct access to its digital representation.
    4. \n
\n

For additional search functionality refindit  can be used. This includes also searches in CrossRef, DataCite, PubMed, RefBank, GNUB and Mendeley.

\n

Upload guideline

\n

A provisional guideline how to upload is here.

\n

 

\n

 

\n

 

\n

 

\n

 

", "title": "Biodiversity Literature Repository", "type": { "id": "topic" }, "website": "https://www.biolitrepo.org" }, "revision_id": 15, "slug": "biosyslit", "theme": { "brand": "biosyslit", "enabled": true, "style": { "font": { "family": "Arial, sans-serif", "size": "16px", "weight": 600 }, "mainHeaderBackgroundColor": "#FFFFFF", "primaryColor": "#636363", "primaryTextColor": "#FFFFFF", "secondaryColor": "#7eb13e", "secondaryTextColor": "#FFFFFF", "tertiaryColor": "#7eb13e", "tertiaryTextColor": "#FFFFFF" } }, "updated": "2025-04-07T12:05:37.615917+00:00" }, "revision_id": 8, "slug": "batlit", "updated": "2025-04-07T11:53:19.512443+00:00" }, { "access": { "member_policy": "open", "members_visibility": "public", "record_submission_policy": "open", "review_policy": "open", "visibility": "public" }, "children": { "allow": true }, "created": "2013-11-11T14:14:18+00:00", "custom_fields": {}, "deletion_status": { "is_deleted": false, "status": "P" }, "id": "c529f97d-f8cb-4c13-a439-9e36891694c2", "links": {}, "metadata": { "curation_policy": "
    \n
  1. If an uploaded document has an existing DOI, it will be kept. If there is no DOI, a Zenodo DOI will be minted for the item.
    2. \n
  2. Items with Open Access remain Open Access.
    3. \n
  3. Items with closed access remain closed. If they are published on 31.12.1999 or earlier, they are made accessible for reading. Please consult your national copyright law for conditions of reuse.
    4. \n
  4. To upload publications, please contact info@plazi.org.
    5. \n
", "description": "A community to share publications related to bio-systematics.", "funding": [ { "funder": { "id": "051z6e826" } } ], "organizations": [ { "name": "Plazi" } ], "page": "

The Biodiversity Literature Repository (BLR) is to share publications related to bio-systematics. The goal is to provide

\n
    \n
  1. open access to publications cited in publications or in combination with scientific names
    2. \n
  2. open access FAIR data with focus on taxon treatments and figures liberated from publications
    3. \n
  3. a digital object identifier (DOI) to enable citation of the publications and data including direct access to its digital representation.
    4. \n
\n

For additional search functionality refindit  can be used. This includes also searches in CrossRef, DataCite, PubMed, RefBank, GNUB and Mendeley.

\n

Upload guideline

\n

A provisional guideline how to upload is here.

\n

 

\n

 

\n

 

\n

 

\n

 

", "title": "Biodiversity Literature Repository", "type": { "id": "topic" }, "website": "https://www.biolitrepo.org" }, "revision_id": 15, "slug": "biosyslit", "theme": { "brand": "biosyslit", "enabled": true, "style": { "font": { "family": "Arial, sans-serif", "size": "16px", "weight": 600 }, "mainHeaderBackgroundColor": "#FFFFFF", "primaryColor": "#636363", "primaryTextColor": "#FFFFFF", "secondaryColor": "#7eb13e", "secondaryTextColor": "#FFFFFF", "tertiaryColor": "#7eb13e", "tertiaryTextColor": "#FFFFFF" } }, "updated": "2025-04-07T12:05:37.615917+00:00" } ], "ids": [ "23bc63d8-1a49-4a20-9519-fb3a3e78f2b4", "c529f97d-f8cb-4c13-a439-9e36891694c2" ] }, "id": "13536258", "pids": { "doi": { "client": "datacite", "identifier": "10.5281/zenodo.13536258", "provider": "datacite" } } }, "pids": { "doi": { "client": "datacite", "identifier": "10.5281/zenodo.13536259", "provider": "datacite" }, "oai": { "identifier": "oai:zenodo.org:13536259", "provider": "oai" } }, "revision_id": 11, "stats": { "all_versions": { "data_volume": 878190.0, "downloads": 2, "unique_downloads": 2, "unique_views": 29, "views": 30 }, "this_version": { "data_volume": 878190.0, "downloads": 2, "unique_downloads": 2, "unique_views": 29, "views": 30 } }, "status": "published", "swh": {}, "updated": "2026-04-23T19:02:00.966104+00:00", "versions": { "index": 1, "is_latest": true } }