Diagnostic effectiveness of wire-guided localization for non-palpable breast lesions and its importance in breast cancer management

Breast cancer represents the most prevalent malignant disease among women globally,
accounting for approximately 30% of all female cancers. Wire-guided localization is now a commonly
utilized method for diagnosing breast lesions that are not palpable on clinical examination but can be
identified through the use of mammography (MG) and/or ultrasound (US). The objective of the study was
to determine the cancer prediction rate of the method in patients with non-palpable breast lesions who
underwent excisional biopsy with wire guided localization and to evaluate the diagnostic significance
of the method by comparing age, size, family history, radiomorphologic type, Breast Imaging and Data
System (BI-RADS) category, location, and histopathologic features. Furthermore, the objective was to
elucidate the advantages of the method in breast cancer treatment by determining the re-excision rates
and types according to the surgical margin status of malignant lesions.