The Brainteaser Ontology
type: Ontology
version IRI: schema
imports: Pollution.owl
imports: skos-owl1-dl.rdf
contributor: partners
creator: Nicola Ferro
creator: Giorgio Maria Di Nunzio
creator: Laura Menotti
creator: Guglielmo Faggioli
creator: Stefano Marchesin
creator: Gianmaria Silvello
description: The BRAINTEASER Ontology (BO) jointly models both Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS). BO serves multiple purposes: • to provide a unified and comprehensive conceptual view about ALS and MS, which are typically dealt with separately, allowing us to coherently integrate the data coming from the different medical partners in the project; • to seamlessly represent both retrospective data and prospective data, produced during the lifetime of BRAINTEASER; • to allow for sharing and re-using the BRAINTEASER datasets according to Open Science and FAIR principles.
license: https://creativecommons.org/licenses/by-sa/4.0/
publisher: brainteaser.health
comment: The BRAINTEASER Ontology (BO) jointly models both Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS).

APConcentrationTime
type: ObjectProperty
domain: Class
  union of: Air pollution concentration
  union of: Weather Data
range: Instant
comment: It defines the relationship between air pollution conentration individuals and their time of recording.

administration
type: ObjectProperty
domain: Therapeutic Treatment
range: Administration
comment: It defines the relationship between a therapeutic treatment and the specific administration details.

adverseReaction
type: ObjectProperty
domain: End Therapy Reason
range: Adverse Drug Reaction
comment: It defines the relationship between The end therapy reason and the adverse reaction occurred.

anatomicalLocation
type: ObjectProperty
domain: Class
  union of: Clinical Evaluation
  union of: Diagnostic Imaging
  union of: Onset
  union of: Surgical Procedure
  union of: Trauma
range: Anatomic Site
comment: It defines the location of a trauma, onset, surgical procedure or diagnostic imaging.

birthplace
type: ObjectProperty
domain: Person
range: Place
comment: It defines the relationship between a person and his or her birthplace.

coexistingPregnancy
type: ObjectProperty
domain: Relapse
range: Pregnancy
comment: It defines the relationship between a relapse and a co-occurring pregnancy.

conductedInClinic
type: ObjectProperty
domain: Clinical Trial
range: Clinics and Hospitals
comment: It defines the relationship between a clinical trial and a clinic or hospital. In particular, a clinical trial is conducted in a clinic or hospital.

confirmedPregnancy
type: ObjectProperty
domain: End Therapy Reason
range: Pregnancy
comment: It defines the relationship between the end therapy reason and a pregnancy, meaning the therapeutic treatment was interrupted due to a confirmed pregnancy.

consists
type: ObjectProperty
domain: Event
range: Intervention or Procedure
comment: It defines the relationship between an event and an intervetion or procedure. In particular, an event could consist in an intervention or procedure.

coveredPlace
type: ObjectProperty
domain: SensingDevice
range: Place
comment: It defines the relationship between the sensing device for environmental data and the covered place.

determinedBy
type: ObjectProperty
type: FunctionalProperty
domain: Comorbidity
range: Disease, Disorder or Finding
comment: It defines the relationship between a comorbidity and the disease that determines it.

enrolledIn
type: ObjectProperty
domain: Person
range: Clinical Trial Participation
comment: It defines the relationship between a person and a clinical trial participation. In particular, a person can be enrolled in a clinical trial participation.

filledAppQuestionnaire
type: ObjectProperty
domain: Event
range: Questionnaire filled using a mobile application
comment: Links each app questionnaire to the event in which it was filled.

hasDisease
type: ObjectProperty
domain: Person
range: Disease, Disorder or Finding
comment: It defines the relationship between a person and a disease which he or she suffers from.

hasEthnicity
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Group (social concept)
comment: It defines the patient's ethnicity. For instance, we say that: :Peter :hasEthnicity _:b . _:b a Group (social concept); a skos:Concept.

hasKinship
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Kinship
comment: It defines the relation between a patient and a kinship. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.
note: This property is functional because we refer only to biological kinship thus a person can only have one biological kinship with a specific person.

hasKinshipType
type: ObjectProperty
type: FunctionalProperty
domain: Kinship
range: KinshipType
comment: It defines the relation between a Kinship and a KinshipType. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.

hasOccupation
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Occupation
comment: It defines the relationship between a patient and his or her occupation.

hasRegisteredActivity
type: ObjectProperty
domain: Event
range: Activity
comment: It defines the relationsihip between an event and an activity. In particular, during an event a specific type of activity can be registered.

hasRegisteredCondition
type: ObjectProperty
domain: Event
range: Condition
comment: It defines the relationsihip between an event and a comorbidity. In particular, during an event a preexisting condition can be registered.

inClinicalTrial
type: ObjectProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: Clinical Trial
comment: It defines the relationship between a clinical trial participation and a clinical trial. In particular, a clinical trial participation refers to a clinical trial.

inKinshipWith
type: ObjectProperty
domain: Kinship
range: Person
comment: The relationship of kinship between a patient with another Person (who might also be a Patient)

isAboutDisease
type: ObjectProperty
domain: Clinical Trial
range: Disease, Disorder or Finding
comment: It defines the relationship between a clinical trial and the disease studied in it.

menstrualCycle
type: ObjectProperty
domain: Patient
range: Menstrual Cycle
comment: Links a patient to the information about her menstrual cycle.

observedResult
type: ObjectProperty
domain: Hematology Test
range: Laboratory Test Result
comment: It defines the relationship between an hematology test and the observed laboratory results.

onGene
type: ObjectProperty
domain: Genetic Testing
range: Gene
comment: It defnies the relationship between a genetic testing and a gene. In particular, a genetic testing looks for some genetic mutations on a gene.

ownsSensingDevice
type: ObjectProperty
domain: Person
range: SensingDevice
comment: Links each person to the sensing device they are carrying.

performedTreatment
type: ObjectProperty
domain: Therapeutic Procedure
range: Therapeutic Treatment
comment: It defines the relationship between the therapeutic procedure and the perfomed therapeutic treatments.

pharmacologicSubstance
type: ObjectProperty
domain: Therapeutic Treatment
range: Pharmacologic Substance
comment: It defines the relationship between a therapeutic treatment and the employed pharmacologic subastance.

placeLocation
type: ObjectProperty
type: FunctionalProperty
domain: Residence
range: Place
comment: It defines the relationship between a patient's residence and its location.

pregnancy
type: ObjectProperty
domain: Event
range: Pregnancy
comment: It defines the relationship between an event and a pregnancy that can be registrered during the event.

relapse
type: ObjectProperty
domain: Event
range: Relapse
comment: It defines the relationship between an event and a relapse that can be registered during the event.

requiredMRI
type: ObjectProperty
domain: Relapse
range: Magnetic Resonance Imaging (MRI)
comment: It defines the relationship between a relapse and a MRI that has been required.

residence
type: ObjectProperty
domain: Person
range: Residence
comment: It defines the relationship between a person and his or her residence.

surgicalType
type: ObjectProperty
type: FunctionalProperty
domain: Surgical Procedure
range: Surgical Procedure Type
comment: It defines the realtionship between the surgical procedure and the specific type of surgical procedure.

tested
type: ObjectProperty
domain: Patient
range: Genetic Testing
comment: It defines the relationship betwen a patient and a genetic testing. In particular, a patient can be tested for genetic mutations.

testedForOligoclonalBands
type: ObjectProperty
type: FunctionalProperty
domain: CSF Analysis
range: Oligoclonal Bands
comment: It defines the relationship between a CSF Analysis and a test for the presence of oligoclonal bands.

therapyType
type: ObjectProperty
domain: Therapeutic Treatment
range: Therapeutic Procedure Type
comment: It defines the relationship between the therapeutic treatment and the type of therapeutic procedure that has been administered.

trauma
type: ObjectProperty
domain: Event
range: Trauma
comment: It defines the relationship between an event and a trauma that can be registered during the event.

undergo
type: ObjectProperty
domain: Patient
range: Event
comment: It defines the relationship between patient and event. In particular, a patient can undergo some events.

ALSFRSR_Q1
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Detectable speech disturbance
    one of: Intelligible with repeating
    one of: Normal speech process
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298336
comment: Q1: Speech

ALSFRSR_Q10
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: None
    one of: Occurs at rest: difficulty breathing when either sitting or lying
    one of: Occurs with one or more of the following: eating, bathing, dressing
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298328
comment: Q10: Dyspnea

ALSFRSR_Q10alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: no change
  one of: shortness of breath at rest while either sitting or lying down
  one of: shortness of breath only with walking
  one of: shortness of breath with minimal exertion (i.e. talking, eating, bathing or dressing)
  one of: significant shortness of breath (all of the time) and considering using mechanical ventilation
comment: Do you experience shortness of breath or have difficulty breathing?

ALSFRSR_Q11
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Needs extra pillows in order to sleep (more than two)
    one of: None
    one of: Some difficulty sleeping at night due to shortness of breath, does not routinely use more than two pillows
    one of: Unable to sleep without mechanical assistance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298327
comment: Q11: Orthopnea

ALSFRSR_Q11alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: Unable to sleep without mechanical assistance
  one of: no change
  one of: occasional shortness of breath while lying on back but don't routinely use more that two (2) pillows to sleep
  one of: shortness of breath while lying on back and require more than two pillows (or an equivalent) to sleep
comment: Do you experience shortness of breath or have difficulty breathing while lying down on your back?

ALSFRSR_Q12
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Continuous use of BiPAP during the night
    one of: Intermittent use of BiPAP
    one of: None
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298326
comment: Q12: Respiratory Insufficiency

ALSFRSR_Q12alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: continuous use of BiPAP at night
  one of: continuous use of BiPAP at night and during the day (nearly 24 hours per day)
  one of: intermittent use of BiPAP
  one of: mechanical ventilation by intubation or tracheostomy
  one of: no respiratory support
comment: Do you require respiratory (breathing) support?

ALSFRSR_Q1alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: no change
  one of: noticeable speech difference
  one of: speech has changed; asked often to repeat words or phrases
  one of: speech has changed; sometimes need the use of alternative communication methods (i.e. computer, writing pad, letter board or eye chart)
  one of: unable to communicate verbally
comment: Have you noticed any changes in your speech?

ALSFRSR_Q2
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Moderately excessive saliva; may have minimal drooling
    one of: Normal
    one of: Slight but definite excess of saliva in mouth; may have night time drooling
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298335
comment: Q2: Salivation

ALSFRSR_Q2alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: marked amounts of excessive saliva with some daytime drooling
  one of: marked excessive saliva with marked drooling requiring a constant tissue or handkerchief
  one of: moderate amounts of excessive saliva with or without minimal day time drooling
  one of: no change
  one of: slight but definite excess of saliva with or without night time drooling
comment: Have you noticed any changes (increases) in the amount of saliva in your mouth (regardless of any medication use)?

ALSFRSR_Q3
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Early eating problems - occasional choking
    one of: Normal eating habits
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298334
comment: Q3: Swallowing

ALSFRSR_Q3alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: do not eat anything by mouth and receive all nutrition through a feeding tube (PEG)
  one of: no changes (all foods and liquids)
  one of: some changes in swallowing or occasional choking episodes (including coughing during swallowing)
  one of: unable to eat all consistencies of food and have modified the consistency of foods eaten
  one of: use a feeding tube (PEG) to supplement what is eaten by mouth
comment: Have there been any changes in your ability to swallow?

ALSFRSR_Q4
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: No words are legible, but can still grip pen
    one of: Normal
    one of: Not all words are legible
    one of: Slow
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298333
comment: Q4:Handwriting

ALSFRSR_Q4alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: able to hold a pen but unable to write
  one of: no changes
  one of: not all words are legible
  one of: slower and/or sloppier but all the words are legible
  one of: unable to hold a pen
comment: Has your handwriting changed? Please choose the best answer that describes your handwriting with your dominant (usual) hand without a cuff or brace.

ALSFRSR_Q5
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: integer
comment: Q5: Cutting Food and Handling Utensils (with or without gastrostomy).

ALSFRSR_Q5A
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: Can cut most foods (> 50%), although slow and clumsy; some help needed
  one of: Food must be cut by someone, but can still feed slowly
  one of: Normal
  one of: Somewhat slow and clumsy, but no help needed
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4285407
comment: Q5A: Cutting Food and Handling Utensils (without gastrostomy)

ALSFRSR_Q5Aalt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: food must be cut by someone else but can feed slowly without assistance
  one of: needs to be fed
  one of: no change
  one of: sometimes need help with cutting more difficult foods
  one of: somewhat slow and clumsy (or different than before) but no assistance or adaptive equipment
comment: Cutting food and handling utensils

ALSFRSR_Q5B
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298332
comment: Q5B: Cutting Food and Handling Utensils (with gastrostomy)

ALSFRSR_Q5Balt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: require assistance with closures and fasteners
  one of: unable to perform any of the manipulations
comment: Using a feeding tube (PEG)

ALSFRSR_Q6
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Independent; Can complete self-care with effort or decreased efficiency
    one of: Intermittent assistance or substitute methods
    one of: Needs attendant for self-care
    one of: Normal function
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298331
comment: Q6: Dressing and Hygiene

ALSFRSR_Q6alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: do not perform self-care activities and completely dependent on caregiver
  one of: no change
  one of: perform self-care activities without assistance but with increased effort or decreased efficiency
  one of: require daily assistance
  one of: require intermittent assistance or use different methods (i.e. sit down to get dressed, fasten buttons with a fastener or your non-dominant hand)
comment: Has your ability to dress and perform self-care activities (i.e. bathing, teeth brushing, shaving, combing your hair, other hygienic activities) changed?

ALSFRSR_Q7
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Can turn alone, or adjust sheets, but with great difficulty
    one of: Normal function
    one of: Somewhat slow and clumsy, but no help needed
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4285576
comment: Q7: Truning in Bed and Adjusting Bed Clothes

ALSFRSR_Q7alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: can initiate turning in bed or adjusting the bed clothes but require assistance to complete the task
  one of: can turn in bed and adjust the bed clothes without assistance but it is slower or more clumsy
  one of: can turn in bed or adjust the bedclothes without assistance but with great difficulty
  one of: helpless in bed
  one of: no change
comment: Has your ability to turn in bed and adjust the bed clothes (i.e. cover yourself with the sheet or blanket) changed?

ALSFRSR_Q8
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Early ambulation difficulties
    one of: Non-ambulatory functional movement only
    one of: Normal
    one of: Walks with assistance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298330
comment: Q8: Walking

ALSFRSR_Q8alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: can move legs or stand up but unable to walk from room to room
  one of: cannot walk or move my legs
  one of: no change
  one of: require assistance to walk (i.e. cane, walker, foot brace or hand held assistance)
  one of: walking has changed but do not require any assistance or devices (i.e. foot brace, cane, walker)
comment: Has your ability to walk changed?

ALSFRSR_Q9
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  union of: integer
  union of: Datatype
    one of: Cannot do
    one of: Mild unsteadiness or fatigue
    one of: Needs assistance
    one of: Normal
    one of: Slow
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4298329
comment: Q9: Climbing Stairs

ALSFRSR_Q9alt
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: cannot climb stairs
  one of: no change
  one of: require assistance (i.e. using the handrail, cane or person)
  one of: slower
  one of: unsteady and/or more fatigued
comment: Has your ability to climb stairs changed?

ALSFRS_R_WHO_COMPLETED
type: DatatypeProperty
domain: Self assessed ALSFRS-R questionnaire
range: Datatype
  one of: Caregiver alone
  one of: Patient
  one of: Patient with assistance
  one of: Patient with assistance from caregiver or family member
comment: Please indicate who completed this survey

DYMUS_Q1
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you have difficulties swallowing solid food (such as meat, bread, and the like)?

DYMUS_Q10
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you have weight loss?

DYMUS_Q2
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you have difficulties swallowing liquids (such as water, milk, and the like)?

DYMUS_Q3
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you have a globus sensation in your throat during swallowing?

DYMUS_Q4
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you have food sticking in your throat?

DYMUS_Q5
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you cough or do you have a choking sensation after ingesting solid foods?

DYMUS_Q6
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you cough or do you have a choking sensation after ingesting liquids?

DYMUS_Q7
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you need to swallow several times before completely swallowing solid food?

DYMUS_Q8
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you need to cut food in small pieces before swallowing?

DYMUS_Q9
type: DatatypeProperty
domain: Dysphagia In Multiple Sclerosis
range: boolean
comment: Do you need to take many sips before completely swallowing liquid?

EQ5D5L_Q1
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  one of: I am unable to walk about
  one of: I have moderate problems in walking about
  one of: I have no problems in walking about
  one of: I have severe problems in walking about
  one of: I have slight problems in walking about
comment: Mobility

EQ5D5L_Q2
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  one of: I am unable to wash or dress myself
  one of: I have moderate problems washing or dressing myself
  one of: I have no problems washing or dressing myself
  one of: I have severe problems washing or dressing myself
  one of: I have slight problems washing or dressing myself
comment: Self-care

EQ5D5L_Q3
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  one of: I am unable to do my usual activities
  one of: I have moderate problems doing my usual activities
  one of: I have no problems doing my usual activities
  one of: I have severe problems doing my usual activities
  one of: I have slight problems doing my usual activities
comment: Usual activities

EQ5D5L_Q4
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  one of: I have moderate pain or discomfort
  one of: I have no pain or discomfort
  one of: I have severe pain or discomfort
  one of: I have slight pain or discomfort
comment: Pain/Discomfort

EQ5D5L_Q5
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  one of: I am extremely anxious or depressed
  one of: I am moderately anxious or depressed
  one of: I am not anxious or depressed
  one of: I am severely anxious or depressed
  one of: I am slightly anxious or depressed
comment: Anxiety/Depression

EQ5D5L_Q6
type: DatatypeProperty
domain: European Quality of Life Five Dimension Five Level Scale Questionnaire
range: Datatype
  on datatype: float
  with restrictions:
    min inclusive: 0.0
  with restrictions:
    max inclusive: 100.0
comment: Health today

HADS_Q1
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: A lot of the time
  one of: From time to time, occasionally
  one of: Most of the time
  one of: Not at all
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641379
comment: I feel tense or 'wound up'

HADS_Q10
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Definitely
  one of: I don't take as much care as I should
  one of: I may not take quite as much care
  one of: I take just as much care as ever
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641388
comment: I have lost interest in my appearance

HADS_Q11
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Not at all
  one of: Not very much
  one of: Quite a lot
  one of: Very much indeed
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641389
comment: I feel restless as I have to be on the move

HADS_Q12
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: As much as I ever did
  one of: Definitely less than I used to
  one of: Hardly at all
  one of: Rather less than I used to
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641390
comment: I look forward with enjoyment to things

HADS_Q13
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Not at all
  one of: Not very often
  one of: Quite often
  one of: Very often indeed
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641391
comment: I get sudden feelings of panic

HADS_Q14
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Not often
  one of: Often
  one of: Sometimes
  one of: Very seldom
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641392
comment: I can enjoy a good book or radio or TV program

HADS_Q2
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Definitely as much
  one of: Hardly at all
  one of: Not quite so much
  one of: Only a little
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641380
comment: I still enjoy the things I used to enjoy

HADS_Q3
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: A little, but it doesnt worry me
  one of: Not at all
  one of: Very definitely and quite badly
  one of: Yes, but not too badly
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641381
comment: I get a sort of frightened feeling as if something awful is about to happen

HADS_Q4
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: As much as I always could
  one of: Definitely not so much now
  one of: Not at all
  one of: Not quite so much now
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641382
comment: I can laugh and see the funny side of things

HADS_Q5
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: A great deal of the time
  one of: A lot of the time
  one of: From time to time, but not too often
  one of: Only occasionally
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641383
comment: Worrying thoughts go through my mind

HADS_Q6
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Most of the time
  one of: Not often
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641384
comment: I feel cheerful

HADS_Q7
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Definitely
  one of: Not at all
  one of: Not often
  one of: Usually
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641385
comment: I can sit at ease and feel relaxed

HADS_Q8
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Nearly all the time
  one of: Not at all
  one of: Sometimes
  one of: Very often
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641386
comment: I feel as if I am slowed down

HADS_Q9
type: DatatypeProperty
domain: Hospital Anxiety and Depression Scale
range: Datatype
  one of: Not at all
  one of: Occasionally
  one of: Quite often
  one of: Very often
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3641387
comment: I get a sort of frightened feeling like 'butterflies' in the stomach

IgGIndexCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The IgG index is the ratio of the quotients for IgG and albumin (IgGcsf/IgGs)/(Albcsf/Albs). It is a quantitative analysis of the relationship between CSF IgG and serum IgG, divided by the same relationship for albumin. [Definition Source: Simonsen, Cecilia Smith et al. “The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis.” Multiple sclerosis journal - experimental, translational and clinical vol. 6,1 2055217319901291. 22 Jan. 2020]

MFIS_Q1
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829104
comment: I have been less alert

MFIS_Q10
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3827236
comment: I have trouble maintaining physical effort for long periods

MFIS_Q11
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829103
comment: I have had difficulty making decisions

MFIS_Q12
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829096
comment: I have been less motivated to do anything that requires thinking

MFIS_Q13
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829093
comment: My muscles have felt weak

MFIS_Q14
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829108
comment: I have been physically uncomfortable

MFIS_Q15
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829099
comment: I have had trouble finishing tasks that require thinking

MFIS_Q16
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829107
comment: I have had difficulty organizing my thoughts when doing things at home or at work

MFIS_Q17
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829098
comment: I have been less able to complete tasks that require physical effort

MFIS_Q18
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829092
comment: My thinking has been slowed down

MFIS_Q19
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829100
comment: I have had trouble concentrating

MFIS_Q2
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829102
comment: I have had difficulty paying attention for long periods of time

MFIS_Q20
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829101
comment: I have limited my physical activities

MFIS_Q21
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829091
comment: I have needed to rest more often or for longer periods

MFIS_Q3
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829088
comment: I have been unable to think clearly

MFIS_Q4
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829106
comment: I have been clumsy and uncoordinated

MFIS_Q5
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829105
comment: I have been forgetful

MFIS_Q6
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829090
comment: I have had to pace myself in my physical activities

MFIS_Q7
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829097
comment: I have been less motivated to do anything that requires physical effort

MFIS_Q8
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829095
comment: I have been less motivated to participate in social activities

MFIS_Q9
type: DatatypeProperty
domain: Modified Fatigue Impact Scale
range: Datatype
  one of: Almost always
  one of: Never
  one of: Often
  one of: Rarely
  one of: Sometimes
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829094
comment: I have been limited in my ability to do things away from home

MSInPaediatricAge
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: An indicator of whether the patient contracted Multiple Sclerosis (MS) in paediatric age.

MSQOL54_Q1
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Excellent
  one of: Fair
  one of: Good
  one of: Very good
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828889
comment: In general, would you say your health is:

MSQOL54_Q10
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828905
comment: Does your health limit you in walking several blocks? If so, how much?

MSQOL54_Q11
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828906
comment: Does your health limit you in walking one block? If so, how much?

MSQOL54_Q12
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828914
comment: Does your health limit you in bathing and dressing yourself? If so, how much?

MSQOL54_Q13
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828897
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Cut down on the amount of time you could spend on work or other activities

MSQOL54_Q14
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828898
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Accomplished less than you would like

MSQOL54_Q15
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828895
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Were limited in the kind of work or other activities

MSQOL54_Q16
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828895
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of your physical health? Had difficulty performing the work or other activities (for example, it took extra effor)

MSQOL54_Q17
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828931
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Cut down on the amount of time you could spend on work or other activities

MSQOL54_Q18
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828932
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Accomplished less than you would like

MSQOL54_Q19
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828930
comment: During the past 4 weeks, have you had any of the following problems with your work or other regular daily activities as a result of any emotional problems (such as feeling depressed or anxious). Didn’t do work or other activities as carefully as usual

MSQOL54_Q2
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: About the same
  one of: Much better now than one year ago
  one of: Much worse now than one year ago
  one of: Somewhat better now than one year ago
  one of: Somewhat worse now than one year ago
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828904
comment: Compared to one year ago, how would you rate your health in general now?

MSQOL54_Q20
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Moderately
  one of: Not at all
  one of: Quite a bit
  one of: Slightly
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828928
comment: During the past 4 weeks, to what extent has your physical health or emotional problems interfered with your normal social activities with family, friends, neighbors, or groups?

MSQOL54_Q21
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Mild
  one of: Moderate
  one of: None
  one of: Severe
  one of: Very mild
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828938
comment: How much bodily pain have you had during the past 4 weeks?

MSQOL54_Q22
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A little bit
  one of: Moderately
  one of: Not at all
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828899
comment: During the past 4 weeks, how much did pain interfere with your normal work (including both work outside the home and housework)?

MSQOL54_Q23
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828927
comment: How much of the time during the past 4 weeks did you feel full of pep?

MSQOL54_Q24
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828939
comment: How much of the time during the past 4 weeks have you been a very nervous person?

MSQOL54_Q25
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828920
comment: How much of the time during the past 4 weeks have you felt so down in the dumps that nothing could cheer you up?

MSQOL54_Q26
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828922
comment: How much of the time during the past 4 weeks have you felt calm and peaceful?

MSQOL54_Q27
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828917
comment: How much of the time during the past 4 weeks did you have a lot of energy?

MSQOL54_Q28
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828921
comment: How much of the time during the past 4 weeks have you felt downhearted and blue?

MSQOL54_Q29
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828923
comment: How much of the time during the past 4 weeks did you feel worn out?

MSQOL54_Q3
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828908
comment: Does your health limit you in vigorous activities, such as running, lifting heavy objects, participating in strenuous sports? If so, how much?

MSQOL54_Q30
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828940
comment: How much of the time during the past 4 weeks have you been a happy person?

MSQOL54_Q31
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828925
comment: How much of the time during the past 4 weeks did you feel tired?

MSQOL54_Q32
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828926
comment: How much of the time during the past 4 weeks did you feel rested on waking in the morning?

MSQOL54_Q33
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828892
comment: During the past 4 weeks, how much of the time has your physical health or emotional problems interfered with your social activities (like visiting with friends, relatives, etc.)?

MSQOL54_Q34
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Definitely false
  one of: Definitely true
  one of: Mostly false
  one of: Mostly true
  one of: Not sure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828918
comment: I seem to get sick a little easier than other people

MSQOL54_Q35
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Definitely false
  one of: Definitely true
  one of: Mostly false
  one of: Mostly true
  one of: Not sure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828941
comment: I am as healthy as anybody I know

MSQOL54_Q36
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Definitely false
  one of: Definitely true
  one of: Mostly false
  one of: Mostly true
  one of: Not sure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828929
comment: I expect my health to get worse

MSQOL54_Q37
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Definitely false
  one of: Definitely true
  one of: Mostly false
  one of: Mostly true
  one of: Not sure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828915
comment: My health is excellent

MSQOL54_Q38
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828933
comment: How much of the time during the past 4 weeks were you discouraged by your health problems?

MSQOL54_Q39
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828919
comment: How much of the time during the past 4 weeks were you frustrated about your health?

MSQOL54_Q4
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828909
comment: Does your health limit you in moderate activities, such as moving a table, pushing a vacuum cleaner, bowling, or playing golf?

MSQOL54_Q40
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828916
comment: How much of the time during the past 4 weeks was your health a worry in your life?

MSQOL54_Q41
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828924
comment: How much of the time during the past 4 weeks did you feel weighed down by your health problems?

MSQOL54_Q42
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828935
comment: How much of the time during the past 4 weeks have you had difficulty concentrating and thinking?

MSQOL54_Q43
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828891
comment: How much of the time during the past 4 weeks did you have trouble keeping your attention on an activity for long?

MSQOL54_Q44
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828890
comment: How much of the time during the past 4 weeks have you had trouble with your memory?

MSQOL54_Q45
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A good bit of the time
  one of: A little of the time
  one of: All of the time
  one of: Most of the time
  one of: None of the time
  one of: Some of the time
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828901
comment: How much of the time during the past 4 weeks have others, such as family members or friends, noticed that you have trouble with your memory or problems with your concentration?

MSQOL54_Q46
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A little of a problem
  one of: Not a problem
  one of: Somewhat of a problem
  one of: Very much a problem
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828902
comment: How much of a problem was the lack of sexual interest for you during the past 4 weeks?

MSQOL54_Q47
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A little of a problem
  one of: Not a problem
  one of: Somewhat of a problem
  one of: Very much a problem
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3827368
comment: How much of a problem was the difficulty getting or keeping an erection for you during the past 4 weeks?

MSQOL54_Q48
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A little of a problem
  one of: Not a problem
  one of: Somewhat of a problem
  one of: Very much a problem
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828934
comment: How much of a problem was the difficulty having orgasm for you during the past 4 weeks?

MSQOL54_Q49
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: A little of a problem
  one of: Not a problem
  one of: Somewhat of a problem
  one of: Very much a problem
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828942
comment: How much of a problem was the for ability to satisfy sexual partner you during the past 4 weeks?

MSQOL54_Q5
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828910
comment: Does your health limit you in lifting or carrying groceries? If so, how much?

MSQOL54_Q50
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Neither satisfied nor dissatisfied
  one of: Somewhat dissatisfied
  one of: Somewhat satisfied
  one of: Very dissatisfied
  one of: Very satisfied
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3827367
comment: Overall, how satisfied were you with your sexual function during the past 4 weeks?

MSQOL54_Q51
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Extremely
  one of: Moderately
  one of: Not at all
  one of: Quite a bit
  one of: Slightly
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828937
comment: During the past 4 weeks, to what extent have problems with your bowel or bladder function interfered with your normal social activities with family, friends, neighbors, or groups?

MSQOL54_Q52
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Extremely
  one of: Moderately
  one of: Not at all
  one of: Quite a bit
  one of: Slightly
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828900
comment: During the past 4 weeks, how much did pain interfere with your enjoyment of life?

MSQOL54_Q53
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  on datatype: float
  with restrictions:
    min inclusive: 0.0
  with restrictions:
    max inclusive: 10.0
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828893
comment: Overall, how would you rate your own quality-of-life?

MSQOL54_Q54
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: Delighted
  one of: Mixed - about equally satisfied and dissatisfied
  one of: Mostly dissatisfied
  one of: Mostly satisfied
  one of: Pleased
  one of: Terrible
  one of: Unhappy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828936
comment: Which best describes how you feel about your life as a whole?

MSQOL54_Q6
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828911
comment: Does your health limit you in climbing several flights of stair? If so, how much?

MSQOL54_Q7
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828912
comment: Does your health limit you in climbing one flights of stair? If so, how much?

MSQOL54_Q8
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828913
comment: Does your health limit you in bending, kneeling, or stooping? If so, how much?

MSQOL54_Q9
type: DatatypeProperty
domain: MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
range: Datatype
  one of: No, not limited at all
  one of: Yes, limited a little
  one of: Yes, limited a lot
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3828907
comment: Does your health limit you in walking more than a mile? If so, how much?

PFTs_FEV1_L
type: DatatypeProperty
domain: Pulmonary function testing
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0849974
comment: A test of lung function, the FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. It is the most frequently used index for assessing bronchoconstriction or bronchodilatation. [Definition Source: NCI]

PFTs_FEV1_P
type: DatatypeProperty
domain: Pulmonary function testing
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0849974
comment: A test of lung function, the FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. It is the most frequently used index for assessing bronchoconstriction or bronchodilatation. [Definition Source: NCI]

PFTs_FEV6_L
type: DatatypeProperty
domain: Pulmonary function testing
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1708092
comment: A test of lung function, the FEV6 is the volume exhaled during six seconds of a forced expiratory maneuver started from the level of total lung capacity. [Definition Source: NCI]

PFTs_FEV6_P
type: DatatypeProperty
domain: Pulmonary function testing
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1708092
comment: A test of lung function, the FEV6 is the volume exhaled during six seconds of a forced expiratory maneuver started from the level of total lung capacity. [Definition Source: NCI]

PSQI_Q1
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: time
comment: During the past month, what time have you usually gone to bed at night?

PSQI_Q10
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: No bed partner or room mate
  one of: Partner in same bed
  one of: Partner/room mate in other room
  one of: Partner/room mate in same room but not same bed
comment: Do you have a bed partner or room mate?

PSQI_Q11A
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Loud snoring

PSQI_Q11B
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Long pauses between breaths while asleep

PSQI_Q11C
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Legs twitching or jerking while you sleep

PSQI_Q11D
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Episodes of disorientation or confusion during sleep

PSQI_Q11E
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Other restlessness while you sleep, please describe

PSQI_Q2
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: int
comment: During the past month, how long (in minutes) has it usually taken you to fall asleep each night?

PSQI_Q3
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: time
comment: During the past month, what time have you usually gotten up in the morning?

PSQI_Q4
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: int
comment: During the past month, how many hours of actual sleep did you get at night? (This may be different than the number of hours you spent in bed.)

PSQI_Q5A
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Cannot get to sleep within 30 minutes

PSQI_Q5B
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Wake up in the middle of the night or early morning

PSQI_Q5C
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Have to get up to use the bathroom

PSQI_Q5D
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Cannot breathe comfortably

PSQI_Q5E
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Cough or snore loudly

PSQI_Q5F
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Feel too cold

PSQI_Q5G
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Feel too hot

PSQI_Q5H
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Have bad dreams

PSQI_Q5I
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: Have pain

PSQI_Q5J_1
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: PlainLiteral
comment: Other reason(s), please describe:

PSQI_Q5J_2
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: how often have you had trouble sleeping because of this?

PSQI_Q6
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: During the past month, how often have you taken medicine to help you sleep (prescribed or “over the counter”)?

PSQI_Q7
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Less than once a week
  one of: Not during the past month
  one of: Once or twice a week
  one of: Three or more times a week
comment: During the past month, how often have you had trouble staying awake while driving, eating meals, or engaging in social activity?

PSQI_Q8
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: A very big problem
  one of: No problem at all
  one of: Only a very slight problem
  one of: Somewhat of a problem
comment: During the past month, how much of a problem has it been for you to keep up enough enthusiasm to get things done?

PSQI_Q9
type: DatatypeProperty
domain: Pittsburgh Sleep Quality Index
range: Datatype
  one of: Fairly bad
  one of: Fairly good
  one of: Very bad
  one of: Very good
comment: During the past month, how would you rate your sleep quality overall?

SLEEP_ALS_Q1
type: DatatypeProperty
domain: Sleep Quality
range: Datatype
  on datatype: float
  with restrictions:
    min inclusive: 0.0
  with restrictions:
    max inclusive: 10.0
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4054285
comment: During the last 7 days, how would you rate your sleep quality overall? Choose a number from 1 to 10 that best describes your sleep quality

VAS_Q1
type: DatatypeProperty
domain: Visual Analogue Scale
range: Datatype
  on datatype: float
  with restrictions:
    min inclusive: 0.0
  with restrictions:
    max inclusive: 10.0
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042815
comment: Choose a number from 0 to 10 that best describes your pain

WEIGHT_Q1
type: DatatypeProperty
domain: Weight
range: float
comment: Please, enter your weight

abdominalSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an abdominal surgery.

activeKilocalories
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Active kilocalories registered by the wearable device. [uom: kcal]

activeTime
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Active time registered by the wearable device. [uom: seconds]

activityDistance
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Activity distance registered by the wearable device. [uom: meters]

activityEndYear
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: The year in which an activity ended.

activityIntensity
type: DatatypeProperty
domain: Physical Activity
range: Datatype
  one of: Intense
  one of: Moderate
  one of: Professional
  one of: Soft
comment: The level of intensity with which the physical activity is carried out.

activityStartYear
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: The year in which the activity started.

activitySteps
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Activity steps registered by the wearable device.

activityStepsGoal
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Activity steps goal registered by the wearable device.

activityStressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: Activity stress duration registered by the wearable device. [uom: seconds]

activityType
type: DatatypeProperty
domain: Physical Activity
range: PlainLiteral
comment: The type of physical activity carried out.

administrationFrequency
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
comment: The frequency of administration of the pharmacological substance.

administrationRoute
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013153
comment: Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. [Definition Source: NCI][attribution: ICH]

administrationUoM
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
comment: The Unit of Measure (UoM) of the adminstration dose.

administrationDose
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: float
comment: A definite quantity of a medicine or drug given or prescribed to be given at one time. [Definition Source: Oxford English Dictionary]

ageBaseline
type: DatatypeProperty
domain: Patient
range: float
comment: The MS patient's age at baseline. Expressed in years.

ageDiagnosis
type: DatatypeProperty
domain: Diagnosis
range: float
comment: Age of the patient at the diagnosis.

ageOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: float
comment: Age of the patient at the onset.

albuminCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of albumin present in a sample of CSF. Unit of measure : [mg/l].

alcoholUse
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: boolean
comment: Whether a patient drinks alcohol.

alive
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: Whether the patient is still alive.

alsfrs1
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 1 for ALSFRS: Speech.

alsfrs10
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 10 for Revised ALSFRS: Dyspnea.

alsfrs11
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 11 for Revised ALSFRS: Orthopnea.

alsfrs12
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 12 for Revised ALSFRS: Respiratory Insufficiency.

alsfrs2
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 2 for ALSFRS: Salivation.

alsfrs3
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 3 for ALSFRS: Swallowing.

alsfrs4
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 4 for ALSFRS: Handwriting.

alsfrs5
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 5 for ALSFRS: Cutting food and handling utensilis.

alsfrs6
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 6 for ALSFRS: Dressing and hygiene.

alsfrs7
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 7 for ALSFRS: Turning in bed and adjusting blankets.

alsfrs8
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 8 for ALSFRS: Walking.

alsfrs9
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 9 for ALSFRS: Climbing Stairs.

alsfrsOriginal10
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Original item 10 for ALSFRS: Breathing.

alterationCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: Datatype
  one of: atypical alteration for MS
  one of: normal
  one of: traumatic
  one of: typical alteration for MS
comment: Whether the CSF specimen is normal or presents alterations.

ambulationEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for ambulation.

ambulationEDSSAssistance
type: DatatypeProperty
domain: Expanded Disability Status Scale (EDSS)
range: boolean
comment: Whether the patient used assistance to perform the ambulation test.

ambulationEDSSObservedTime
type: DatatypeProperty
domain: Expanded Disability Status Scale (EDSS)
range: float
comment: Observed time to walk 500m (in minutes)

ambulationEDSSPatientDistance
type: DatatypeProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Distance reported by patient (in meters) without stopping

ambulationEDSSPatientTime
type: DatatypeProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Time reported by patient (in minutes) without stopping

ankleFootOrthosis
type: DatatypeProperty
domain: Walk Test
range: boolean
comment: Whether the patient has ankle/foot orthosis.

ashworthLeftArm
type: DatatypeProperty
domain: Muscle Tone Assessment
range: Datatype
  on datatype: integer
  with restrictions:
    min inclusive: 0
  with restrictions:
    max inclusive: 4
comment: Muscle tone assessment of the left arm.

ashworthLeftLeg
type: DatatypeProperty
domain: Muscle Tone Assessment
range: Datatype
  on datatype: integer
  with restrictions:
    min inclusive: 0
  with restrictions:
    max inclusive: 4
comment: Muscle tone assessment of the left leg.

ashworthRightArm
type: DatatypeProperty
domain: Muscle Tone Assessment
range: Datatype
  on datatype: integer
  with restrictions:
    min inclusive: 0
  with restrictions:
    max inclusive: 4
comment: Muscle tone assessment of the right arm.

ashworthRightLeg
type: DatatypeProperty
domain: Muscle Tone Assessment
range: Datatype
  on datatype: integer
  with restrictions:
    min inclusive: 0
  with restrictions:
    max inclusive: 4
comment: Muscle tone assessment of the right leg.

autoimmuneDisease
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had an autoimmune disease.

averageHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: Average heart rate registered by the wearable device. [uom: bpm]

averageMeasurement
type: DatatypeProperty
domain: Class
  union of: Air pollution concentration
  union of: Weather Data
range: float
comment: Average of valid measurements in that week; if there are no valid measurements in that week, it is denoted as NA.

averageStressLevel
type: DatatypeProperty
domain: Stress Level
range: float
comment: Average stress level registered by the wearable device.

awajiClinicalLMNBulbar
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Bulbar region.

awajiClinicalLMNCervical
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Cervical region.

awajiClinicalLMNLumboSacral
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Lumbo-Sacral region.

awajiClinicalLMNThoracic
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Lower Motor Neuron (LMN) signs in the Thoracic region.

awajiClinicalUMNBulbar
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Bulbar region.

awajiClinicalUMNCervical
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Cervical region.

awajiClinicalUMNLumboSacral
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents clinical Upper Motor Neuron (UMN) signs in the Lumbo-Sacral region.

awajiDiagnosisCriteria
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: Definite
  one of: Possible
  one of: Probable
comment: ALS diagnosis according to the Awaji criteria.

awajiEMGLMNBulbar
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents Lower Motor Neuron (LMN) signs in the Bulbar region, using needle electromyography (EMG).

awajiEMGLMNCervical
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents Lower Motor Neuron (LMN) signs in the Cervical region, using needle electromyography (EMG).

awajiEMGLMNLumboSacral
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents Lower Motor Neuron (LMN) signs in the Lumbo-Sacral region, using needle electromyography (EMG).

awajiEMGLMNThoracic
type: DatatypeProperty
domain: Awaji Clinical Evaluation
range: Datatype
  one of: ND
  one of: No
  one of: Yes
comment: Whether the patient presents Lower Motor Neuron (LMN) signs in the Thoracic region, using needle electromyography (EMG).

awakeDuration
type: DatatypeProperty
domain: Sleep Data
range: float
comment: Awake duration registered by the wearable device. [uom: seconds]

axialOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced axial onset. The Axial Skeleton is the part of the skeleton that includes the skull and spinal column and sternum and ribs. [Definition Source: NCI]

basalKilocalories
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Total basal calories registered by the wearable device. [uom: kcal]

baselineHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The baseline heart rate (at stimulus onset).

beatToBeatAI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Area Index, defined as the cumulative area of the sectors corresponding to the points that are located above Line of Identity (LI) divided by the cumulative area of sectors corresponding to all points in the Poincaré plot except those that are located on LI.

beatToBeatC2a
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The contributions of heart rate acceleration in long-term Heart Rate Variability (HRV) (Piskorski, 2011).

beatToBeatC2d
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The contributions of heart rate deceleration in long-term HRV (Piskorski, 2011).

beatToBeatCSI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The Cardiac Sympathetic Index (Toichi, 1997), calculated by dividing the longitudinal variability of the Poincaré plot by its transverse variability.

beatToBeatCSIModified
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The modified CSI (Jeppesen, 2014) obtained by dividing the square of the longitudinal variability by its transverse variability.

beatToBeatCVI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The Cardiac Sympathetic Index (Toichi, 1997), equal to the logarithm of the product of longitudinal variability of the Poincaré plot by its transverse variability.

beatToBeatCVSD
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The root mean square of the sum of successive differences (RMSSD) divided by the mean of the RR intervals (MeanNN).

beatToBeatCa
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The total contributions of heart rate accelerations to HRV.

beatToBeatCd
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The total contributions of heart rate accelerations to HRV.

beatToBeatGI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Guzik’s Index, defined as the distance of points above line of identity (LI) to LI divided by the distance of all points in Poincaré plot to LI except those that are located on LI.

beatToBeatHTI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The HRV triangular index, measuring the total number of RR intervals divided by the height of the RR intervals histogram.

beatToBeatHcvNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The median absolute deviation of the RR intervals (MadNN) divided by the median of the absolute differences of their successive differences (MedianNN).

beatToBeatIALS
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Inverse of the average length of the acceleration/deceleration segments.

beatToBeatIqrNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The interquartile range (IQR) of the RR intervals.

beatToBeatMadNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The median absolute deviation of the RR intervals.

beatToBeatMeanNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The mean of the RR intervals.

beatToBeatMedianNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The median of the absolute values of the successive differences between RR intervals.

beatToBeatPAS
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Percentage of NN intervals in alternation segments

beatToBeatPI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Porta’s Index, defined as the number of points below LI divided by the total number of points in Poincaré plot except those that are located on LI.

beatToBeatPIP
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Percentage of inflection points of the RR intervals series.

beatToBeatPNN20
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The proportion of RR intervals greater than 20ms, out of the total number of RR intervals.

beatToBeatPNN50
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The proportion of RR intervals greater than 50ms, out of the total number of RR intervals.

beatToBeatPSS
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Percentage of short segments

beatToBeatRmssd
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The square root of the mean of the sum of successive differences between adjacent RR intervals.

beatToBeatSD1
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: SD1 is a measure of the spread of RR intervals on the Poincaré plot perpendicular to the line of identity. It is an index of short-term RR interval fluctuations, i.e., beat-to-beat variability. It is equivalent (although on another scale) to RMSSD, and therefore it is redundant to report correlations with both (Ciccone, 2017).

beatToBeatSD1SD2
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The ratio between short- and long-term fluctuations of the RR intervals (SD1 divided by SD2).

beatToBeatSD1a
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Short-term variance of contributions of accelerations (shortenings of RR intervals) (Piskorski, 2011).

beatToBeatSD1d
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Short-term variance of contributions of decelerations (prolongations of RR intervals) (Piskorski, 2011).

beatToBeatSD2
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Measure of the spread of RR intervals on the Poincaré plot along the line of identity. It is an index of long-term RR interval fluctuations.

beatToBeatSDANN1
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The standard deviation of average RR intervals extracted from 1-minute segments of time series data.

beatToBeatSDANN2
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The standard deviation of average RR intervals extracted from 2-minutes segments of time series data.

beatToBeatSDANN5
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The standard deviation of average RR intervals extracted from 5-minutes segments of time series data.

beatToBeatSDNN
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The standard deviation of the RR intervals.

beatToBeatSDNNI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The mean of the standard deviations of RR intervals extracted from 2-minutes segments of time series data.

beatToBeatSDNNI1
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The mean of the standard deviations of RR intervals extracted from 1-minute segments of time series data.

beatToBeatSDNNI5
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The mean of the standard deviations of RR intervals extracted from 5-minutes segments of time series data.

beatToBeatSDNNa
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Total variance of contributions of accelerations (shortenings of RR intervals) (Piskorski, 2011).

beatToBeatSDNNd
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Total variance of contributions of decelerations (prolongations of RR intervals) (Piskorski, 2011).

beatToBeatSDSD
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: The standard deviation of the successive differences between RR intervals.

beatToBeatSI
type: DatatypeProperty
domain: Beat-To-Beat Data
range: float
comment: Slope Index, defined as the phase angle of points above LI divided by the phase angle of all points in Poincaré plot except those that are located on LI.

before20Years
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: boolean
comment: Whether a patient smoked before the age of 20.

birthYear
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: gYear
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2826771
comment: The year in which a person was born. [Definition Source: NCI]

bmrKilocalories
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: BMR kilocalories registered by the wearable device. [uom: kcal]

bmvtrTotal
type: DatatypeProperty
domain: Brief Visuospatial Memory Test-Revised
range: integer
comment: Brief Visuospatial Memory Test-Revised Total Score.

bodyMassIndex
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
comment: Weight in kilograms divided by the square of the height in metres, used esp. as an indicator of obesity or general nutritional status; also called Quetelet index; abbreviated BMI. [Definition Source: Oxford English Dictionary]

bowelAndBladderEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for bowel and bladder functions.

bowelAndBladderRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved bowel and bladder functions.

brainAtrophyMRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: Datatype
  one of: high
  one of: mild
  one of: moderate
  one of: none
comment: The level of brain atrophy (cerebral atrophy) found in the brain of the patient shown by the MRI.

brainstemRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the brainstem functions.

brainstemEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for brainstem functions.

bulbarOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced bulbar onset, which means he or she first notice speech or swallowing problems. [Definition Source: National Institute of Neurological Disorders and Stroke]

bulbarSubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Bulbar ALSFRS subscore. Sum of items: 1, 2 and 3.

burdenT1Lesions
type: DatatypeProperty
domain: Magnetic Resonance Imaging (MRI)
range: Datatype
  one of: High
  one of: Mild
  one of: Moderate
comment: The burden of T2 lesions showed in the MRI.

burdenT2Lesions
type: DatatypeProperty
domain: Magnetic Resonance Imaging (MRI)
range: Datatype
  one of: High
  one of: Mild
  one of: Moderate
comment: The burden of T1 lesions showed in the MRI.

bvmtrTrial1
type: DatatypeProperty
domain: Brief Visuospatial Memory Test-Revised
range: integer
comment: Brief Visuospatial Memory Test-Revised Immediate Recall Trial 1 Score.

bvmtrTrial2
type: DatatypeProperty
domain: Brief Visuospatial Memory Test-Revised
range: integer
comment: Brief Visuospatial Memory Test-Revised Immediate Recall Trial 2 Score.

bvmtrTrial3
type: DatatypeProperty
domain: Brief Visuospatial Memory Test-Revised
range: integer
comment: Brief Visuospatial Memory Test-Revised Immediate Recall Trial 3 Score.

cardiacDisease
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a cardiac disease.

cerebellarEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for cerebellar functions.

cerebellarRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the celebellar functions.

cerebralEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for cerebral functions.

cervicalSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a cervical spine surgery.

cervicalTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a cervical trauma.

clinicalTrialDescription
type: DatatypeProperty
domain: Clinical Trial
range: PlainLiteral
comment: The description of a clinical trial.

clinicallyEvaluatedEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: float
comment: Expanded Disability Status Score (EDSS) evaluated by the physician.

cognitivePhenotype
type: DatatypeProperty
domain: Patient
range: PlainLiteral
comment: Cognitive phenotype is defined as the broad set of measurable parameters associated with cognition, including not only behavioral symptoms and specific neurocognitive probes, but also physiological and structural indices which we can use to characterize cognitive function at the neural systems. [Source: doi.org/10.1007/978-1-4614-3846-5_4]

cognitiveRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the mental functions.

comorbiditySeverity
type: DatatypeProperty
type: FunctionalProperty
domain: Comorbidity
range: Datatype
  one of: life risk
  one of: moderate
  one of: serious
  one of: slight
comment: The severity of a comorbidity.

comorbidityTreatment
type: DatatypeProperty
domain: Comorbidity
range: PlainLiteral
comment: The treatment used for the comorbidity.

componentName
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: PlainLiteral
comment: The name of the hematopoietic component tested in the laboratory test result.

concentrationMeasurement
type: DatatypeProperty
domain: Class
  union of: Air pollution concentration
  union of: Weather Data
range: float
comment: Raw air pollution concentration measured by the Sensing Device.

conditionEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Condition
range: date
comment: The calendar date of the end of the registered conditon.

The calendar date of the start of the registered conditon.
type: DatatypeProperty
type: FunctionalProperty
domain: Condition
range: date
label: conditionStart

contiguousLesionsMRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected the presence of extended contiguous lesions equal to or greater than three vertical segments.

cvltIITotalCorrect
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Total Corrected Score.

cvltIITotalInterferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Total Interferences Score.

cvltIITotalPerseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Total Perseverations Score.

cvltIITrial1Correct
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 1 Corrected Score.

cvltIITrial1Interferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 1 Interferences Score.

cvltIITrial1Perseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 1 Perseverations Score.

cvltIITrial2Correct
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 2 Corrected Score.

cvltIITrial2Interferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 2 Interferences Score.

cvltIITrial2Perseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 2 Perseverations Score.

cvltIITrial3Correct
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 3 Corrected Score.

cvltIITrial3Interferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 3 Interferences Score.

cvltIITrial3Perseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 3 Perseverations Score.

cvltIITrial4Correct
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 4 Corrected Score.

cvltIITrial4Interferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 4 Interferences Score.

cvltIITrial4Perseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 4 Perseverations Score.

cvltIITrial5Correct
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 5 Corrected Score.

cvltIITrial5Interferences
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 5 Interferences Score.

cvltIITrial5Perseverations
type: DatatypeProperty
domain: California Verbal Learning Test - Second Edition
range: integer
comment: California Verbal Learning Test Trial 5 Perseverations Score.

dailyCigarettes
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: integer
comment: The number of cigarettes smoked in one day on average.

deathCause
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007465
comment: The circumstance or condition that results in the death of a living being. [Definition Source: NCI]

deathDate
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: date
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1148348
comment: The calendar date of subject's death. [Definition Source: NCI]

deepSleepDuration
type: DatatypeProperty
domain: Sleep Data
range: float
comment: Deep sleep duration registered by the wearable device. [uom: seconds]

dextricity
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0449722
comment: The preferred hand of use for controlled and efficient performance of motor tasks. [Definition Source: NCI]

diabetes
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had diabetes.

diagnosticCriteria
type: DatatypeProperty
type: FunctionalProperty
domain: Diagnosis
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0679228
comment: A standard from which a judgment concerning a medical diagnosis can be established. [Definition Source: NCI]

diagnosticCriteriaLabel
type: DatatypeProperty
domain: Diagnosis
range: PlainLiteral
comment: Criteria for the diagnosis. Possible values are: {Diagnosed MS, Neuromyelitis optica, NA}

diagnosticDelay
type: DatatypeProperty
domain: Diagnosis
range: float
comment: The Difference (in days) between the date of diagnosis and the date of onset. (diagnosis_date-onset_date)

diet
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012155
comment: Regular course of eating and drinking adopted by a person or animal. [Definition Source: MSH]

dominantHandTrial1
type: DatatypeProperty
domain: Hand Dexterity
range: float
comment: Hand Dextrcity on dominant hand (Trial 1).

dominantHandTrial2
type: DatatypeProperty
domain: Hand Dexterity
range: float
comment: Hand Dextrcity on dominant hand (Trial 2).

dominantHandTrialDone
type: DatatypeProperty
domain: Hand Dexterity
range: boolean
comment: Whether the hand dextricity was performed on the dominant hand.

dyslipidemia
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had dyslipidemia.

ecasALSnonSpecificScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen ALS non-specific Score.

ecasALSspecificScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen ALS-specific Score.

ecasCarerInterviewScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Carer Interview Score.

ecasExecutiveAlternation
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Executive Alteration score.

ecasExecutiveFluencyS
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Executive Fluency of Letter S Score.

ecasExecutiveFluencyT
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Executive Fluency of Letter T Score.

ecasExecutiveScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Executive Score.

ecasExecutiveSentenceCompletion
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Executive Sentence Completion Score.

ecasHasCarerInterview
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether during the ECAS test a carer interview was performed.

ecasLanguageComprehension
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Language Comprehension Score.

ecasLanguageNaming
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Language Naming Score.

ecasLanguageScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Language Score.

ecasLanguageSpelling
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Language Spelling score.

ecasMemoryDelayedRecall
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Memory Delayed Recall Score.

ecasMemoryDelayedRecognition
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Edinburgh Cognitive and Behavioural ALS Screen Memory Delayed Recognition Score.

ecasMemoryImmediateRecall
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Memory Immediate Recall Score.

ecasMemoryScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Memory Score.

ecasPsychosisScreenScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Psychosis Screen Score.

ecasReverseDigitSpan
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Reverse Digit Span Score.

ecasSocialCognition
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Social Cognition Score.

ecasSymptomsApathyOrInertia
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Whether the patient presents apathy or inertia symptoms.

ecasSymptomsChangePrevBehaviour
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether the patient presents symptoms change from previous behaviour.

ecasSymptomsDisinhibition
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether the patient presents disinhibition symptoms.

ecasSymptomsHyperorality
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether the patient presents hyperorality symptoms.

ecasSymptomsLossSympathyOrEmpathy
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether the patient presents loss sympathy or empathy symptoms.

ecasSymptomsPerseverativeSterotyped
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: boolean
comment: Whether the patient presents perseverative stereotyped symptoms.

ecasTotalScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Total Score.

ecasVerbalFluencyScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Verbal Fluency score.

ecasVisuospatialCubeCounting
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Cube Counting Score.

ecasVisuospatialDotCounting
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Dot Counting Score.

ecasVisuospatialNumberLocation
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Number Location Score.

ecasVisuospatialScore
type: DatatypeProperty
domain: Edinburgh Cognitive and Behavioural ALS Screen
range: integer
comment: Edinburgh Cognitive and Behavioural ALS Screen Visuospatial Score.

educationLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: int
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013658
comment: An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. [Definition Source: NCI]

endReason
type: DatatypeProperty
domain: Clinical Trial Participation
range: PlainLiteral
comment: The reason for the interruption of the subject's participation in a clinical trial.

endTherapyReason
type: DatatypeProperty
type: FunctionalProperty
domain: End Therapy Reason
range: PlainLiteral
comment: The reason for the interruption of the therapeutic treatment.

eventEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Event
range: date
comment: The calendar date of the end of the event.

eventStart
type: DatatypeProperty
type: FunctionalProperty
domain: Event
range: date
comment: The calendar date of the start of the event.

everSmoked
type: DatatypeProperty
domain: Smoking
range: boolean
comment: Whether a patient has ever smoked or not.

evokedPotentialsLocation
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: left
  one of: lower
  one of: lower left
  one of: lower right
  one of: right
  one of: upper
  one of: upper left
  one of: upper right
comment: The body location of the evoked potential test.
note: Locations "upper left/upper right/lower left/lower right" can only be used for Evoked Potentials of type 'somatosensory' or 'motor'.

evokedPotentialsResponse
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: altered
  one of: normal
comment: The evoked potential function test result.

evokedPotentialsType
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: auditory
  one of: motor
  one of: somatosensory
  one of: visual
comment: Whether the test was a Visual Evoked Potential (VEP), Auditory Evoked Potential (AEP), Somatosensory Evoked Potential (SSEP) or Motor Evoked Potential (MEP).

factorsAffectedHandTrial
type: DatatypeProperty
domain: Hand Dexterity
range: Datatype
  one of: Difficulty seeing
  one of: Dropped PEG
  one of: Has a Cold
  one of: Other
  one of: Talked
comment: The factors that affected the hand dextricity test.

familiarHistoryALS
type: DatatypeProperty
domain: Patient
range: boolean
comment: Whether someone in the patient's faimily suffered from ALS. This property only applies to ALS patients.

floorsClimbed
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Floors climbed registered by the wearable device.

floorsClimbedGoal
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Floors climbed goal registered by the wearable device.

gadoliniumLesionsT1MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected some gadolinium-enhanced lesions in T1.

gadoliniumLesionsT1MRINumber
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: integer
comment: The number of gadolinium-enhanced lesions in T1.

generalizedOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced generalized onset, that are widespread symptoms.

genomeSequencing
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3640076
comment: A procedure that can determine the DNA sequence for nearly the entire genome of an individual. [Definition Source: NCI]

glucoseCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of blood sugar present in a sample of CSF. Unit of measure : [mg/l].

goldCoastExcludingOthers
type: DatatypeProperty
domain: Gold Coast Diagnosis Criteria
range: boolean
comment: Whether other disease processes has been excluded. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]

goldCoastProgressiveMotorImpairment
type: DatatypeProperty
domain: Gold Coast Diagnosis Criteria
range: boolean
comment: Whether the patient presents progressive motor impairment documented by history or repeated clinical assessment, preceded by normal motor function. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]

goldCoastUMNandLMN
type: DatatypeProperty
domain: Gold Coast Diagnosis Criteria
range: boolean
comment: Whether the patient presents UMN and LMN signs in at least one body region. [Source: doi.org/10.1016/j.clinph.2020.04.005 ]

granulocytesCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The percentage of granulocytes present in a sample of CSF. Unit of measure : [%].

hadMajorTrauma
type: DatatypeProperty
domain: Before Onset
range: boolean
comment: Whether a patient had a major trauma before the disease onset.

hadSurgicalIntervention
type: DatatypeProperty
domain: Before Onset
range: boolean
comment: Whether the patient had a surgical intervention before the disease onset.

hasMenstrualCycle
type: DatatypeProperty
domain: Menstrual Cycle
range: boolean
comment: Whether the patient has the menstrual cycle.

hasMutation
type: DatatypeProperty
type: FunctionalProperty
domain: Genetic Testing
range: boolean
comment: Whether the gene tested positive or negative for mutations during genetic testing.

headNeckSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a surgery in the head and neck area.

headTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an head trauma.

height
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0489786
comment: Distance or measurement from the base upwards; altitude; stature (of the human body). [Source: Oxford English Dictionary]

highStressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: High stress duration registered by the wearable device. [uom: seconds]

homeWalkingStatus
type: DatatypeProperty
domain: Clinical Evaluation
range: Datatype
  one of: Crutches
  one of: Fully ambulatory
  one of: Orthosis
  one of: Walker @em
  one of: Walking stick
  one of: Wheelchair
comment: The ambulatory status of the patient within the house. (e.g., whether they walk on their own or they need assistive devices)

hypertension
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had hypertension.

immunoglobulinGCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of Immunoglobulin G (IgG) present in a sample of CSF. Unit of measure : [mg/l].

intensityDurationGoal
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Intensity duration goal registered by the wearable device. [uom: seconds]

isMenstrualCycleRegular
type: DatatypeProperty
domain: Menstrual Cycle
range: boolean
comment: Whether the patient has a regular menstrual cycle.

kingsValue
type: DatatypeProperty
type: FunctionalProperty
domain: King's Clinical Staging Method
range: integer
comment: The patient's disease stage according to the King's Staging System.

lesionsT1MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected some lesions in T1.

lesionsT2MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected some lesions in T2.

leukocytesCountCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of leukocytes present in a sample of CSF. Unit of measure : [/mm3].

lightSleepDuration
type: DatatypeProperty
domain: Sleep Data
range: float
comment: Light sleep duration registered by the wearable device. [uom: seconds]

limbsOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced limb onset, which menas symptoms began in the arms or legs. [Definition Source: National Institute of Neurological Disorders and Stroke]

linearTrendHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The parameter corresponding to the linear trend of heart rate.

lowStressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: Low stress duration registered by the wearable device. [uom: seconds]

lowerLimbSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lower limb surgery.

lumboSacralSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lumbo sacral spine surgery.

lumboSacralTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lumbo sacral trauma.

lymphocytesCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The percentage of lymphocytes present in a sample of CSF. Unit of measure : [%].

maritalStatus
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024819
comment: A demographic parameter indicating a person's current conjugal status. [Definition Source: NCI]

maxHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: Max heart rate registered by the wearable device. [uom: bpm]

maxStressLevel
type: DatatypeProperty
domain: Stress Level
range: float
comment: Max stress level registered by the wearable device.

maxTimeHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The time at which maximum heart rate occurs.

measuredLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: float
comment: The level of the hematopoietic component measured in the laboratory test result.
note: This data property is populated only for numeric-valued test results.

measurementCalibrated
type: DatatypeProperty
domain: Class
  union of: Air pollution concentration
  union of: Weather Data
range: float
comment: Air pollution concentration value with seasonal components and noise removed.

mediumStressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: Medium stress duration registered by the wearable device. [uom: seconds]

menopauseStatus
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829127
comment: An indicator as to whether the female subject is in menopause. [Defintion source: NCI]

metersWalkedFirstMin
type: DatatypeProperty
domain: Walk Test ALS
range: float
comment: How many meters the patient walked in the first minute.

metersWalkedTwoMins
type: DatatypeProperty
domain: Walk Test ALS
range: float
comment: How many meters the patient walked in two minutes.

minHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: Min heart rate registered by the wearable device. [uom: bpm]

minTimeHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The time at which minimum heart rate occurs.

mitosValue
type: DatatypeProperty
type: FunctionalProperty
domain: Milano-Torino Functional Staging System (MiToS)
range: integer
comment: The patient's disease stage according to the MiToS staging system.

moderateIntensityDuration
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Moderate intensity duration registered by the wearable device. [uom: seconds]

moreThan10PercentWeightloss
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: boolean
comment: Whether a patient lost more than 10% of his or her body weight.

motorSubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Motor ALSFRS subscore. Sum of items: 4, 5, 6, 7, 8 and 9.

multipleSclerosisType
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: clinically isolated syndrome (CIS)
  one of: primary progressive MS (PP)
  one of: progressive-relapsing (PR)
  one of: radiologically isolated syndrome (RIS)
  one of: relapsing-remitting MS (RR)
  one of: secondary progressive MS (SP)
comment: The Multiple Sclerosis (MS) disease course identified in the patient.
note: This data property is used only for MS patients.

mutationType
type: DatatypeProperty
domain: Genetic Testing
range: PlainLiteral
comment: The type of mutation observed in the gene during genetic testing.

neckTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
comment: Whether a patient had a neck trauma.

newOrEnlargedLesionsT2MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

newOrEnlargedLesionsT2MRINumber
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: integer
comment: The number of new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

nonDominantHandTrial1
type: DatatypeProperty
domain: Hand Dexterity
range: float
comment: Hand Dextrcity on non-dominant hand (Trial 1).

nonDominantHandTrial2
type: DatatypeProperty
domain: Hand Dexterity
range: float
comment: Hand Dextrcity on non-dominant hand (Trial 2).

nonDominantHandTrialDone
type: DatatypeProperty
domain: Hand Dexterity
range: boolean
comment: Whether the hand dextricity was performed on the dominant hand.

normalLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: boolean
comment: Whether the measured level is within the normal range for the tested hematopoietic component.

notes
type: DatatypeProperty
domain: Patient
range: PlainLiteral
comment: An open box for adding notes about the patient.

numberSpinalCordLesions
type: DatatypeProperty
domain: Magnetic Resonance Imaging (MRI)
range: float
comment: The number of spinal cord lesions showed in the MRI.

oligoclonalBandsNumber
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: integer
comment: The number of oligoclonal bands present in the specimen.

oligoclonalBandsPresence
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: boolean
comment: Whether the tested specimen presents oligoclonal bands.

oligoclonalBandsType
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: Datatype
  one of: in CSF
  one of: in CSF & serum
comment: Whether the oligoclonal bands were found in CSF or in CSF & serum.

onsetElapsedTime
type: DatatypeProperty
type: FunctionalProperty
domain: Before Onset
range: Datatype
  one of: beyond 5years
  one of: within 5 yeras
comment: The time elapsed since the occurrence of an event that happened before the onset.

originalALSFRS
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items: 1,2,3,4,5,6,7,8,9 and old10.

otherFactorsAffectedHandTrial
type: DatatypeProperty
domain: Hand Dexterity
range: PlainLiteral
comment: Other factors that affected the hand dextricity test.

otherOnset
type: DatatypeProperty
domain: Onset
range: Datatype
  union of: PlainLiteral
  union of: boolean
comment: Other symptoms experienced by the patient during onset.

otherRelapse
type: DatatypeProperty
domain: Relapse
range: PlainLiteral
comment: Other functional systems involved in the relapse.

outsideWalkingStatus
type: DatatypeProperty
domain: Clinical Evaluation
range: Datatype
  one of: Crutches
  one of: Fully ambulatory
  one of: Orthosis
  one of: Walker @em
  one of: Walking stick
  one of: Wheelchair
comment: The ambulatory status of the patient when walking outside. (e.g., whether they walk on their own or they need assistive devices)

packYear
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: float
comment: Quantificator of lifetime tobacco exposure defined as: (number of cigarettes smoked per day) X (number of years smoked)/20.

participationEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: date
comment: The calendar date of the end of subject's partiicpation in a clinical trial.

participationStart
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: date
comment: The calendar date of the start of subject's partiicpation in a clinical trial.

pathologicalJCCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: boolean
comment: Whether the JC virus detected in the CSF specimen is pathological.
note: This data property can only be populated in "visuJCTestedCSF" has value True.

pelvicSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a pelivc surgery.

phenotype
type: DatatypeProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4086242
comment: The observable properties present during a disease. [Definition Source: NCI]

placeArea
type: DatatypeProperty
domain: Place
range: Datatype
  one of: city
  one of: rural
  one of: town
  one of: urban
comment: The type of populated area that better describe the place.

positivityResult
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: boolean
comment: Whether the laboratory test result was positive or not.
note: This data property is only populated for positive/negative laboratory test result.

predominantLimbsImpairment
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: both
  one of: distal
  one of: proximal
comment: Whether the patient predominantly presents distal limbs impairment or proximal limbs impairment.
note: This data property is used only for ALS patients.

predominantLimbsSide
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: left
  one of: right
  one of: symmetric
comment: The side of the body that predominantly presents limb impariment.
note: This data property is used only for ALS patients.

predominantMotorNeuron
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: both motor neuron
  one of: lower motor neuron
  one of: upper motor neuron
comment: Whether the patient presents a predominance of lower motor neuron, upper motor neuron or both.
note: This data property is used only for ALS patients.

pregnancyComplications
type: DatatypeProperty
domain: Pregnancy
range: PlainLiteral
comment: Any kind of complication related to the pregnancy.

pregnancyEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: date
comment: The calendar date in which the pregnancy ended.

pregnancyEndEvent
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: PlainLiteral
comment: The event that ended the pregnancy.

pregnancyStart
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: date
comment: The calendar date in which the pregnancy started.

primaryNeoplasm
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a primary neoplasm.

privacyPreservingDate
type: DatatypeProperty
domain: Class
  union of: Air pollution concentration
  union of: Activity
  union of: Questionnaire filled using a mobile application
  union of: Condition
  union of: Event
  union of: Intervention or Procedure
  union of: Pregnancy
  union of: Relapse
  union of: Trauma
  union of: Weather Data
range: float
comment: Privacy preserving date computed according to an algorithm used to extract public instances.

privacyPreservingDeathDate
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: float
comment: Privacy preserving death date computed according to an algorithm used to extract public instances.

procedureEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Intervention or Procedure
range: date
comment: The calendar date of the end of an intervention or procedure.

procedureStart
type: DatatypeProperty
type: FunctionalProperty
domain: Intervention or Procedure
range: date
comment: The calendar start of an intervention or procedure.

proteinsCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of proteins present in a sample of CSF [ mg/l].

pulmonaryAOPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Occlusion pressure at 100 ms (P0.1) is defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit. [Definition Source: Beloncle, F., Piquilloud, L., Olivier, PY. et al. Accuracy of P0.1 measurements performed by ICU ventilators: a bench study. Ann. Intensive Care 9, 104 (2019)]

pulmonaryFEV6
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Forced expiratory volume (FEV) is the amount of air expired in six seconds of the FVC test. [Definition Source: John Hopkins Medicine]

pulmonaryFVCLyingDown
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Forced Vital Capacity (FVC) when patient is lied down.

pulmonaryFVCLyingDownPercentage
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Percentage of FVC lying down.

pulmonaryFVCRel
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The percentage of Forced vital capacity (FVC) is the amount of air exhaled forcefully and quickly after inhaling as much as you can. [Defintion Source: John Hopkins Medicine]

pulmonaryFVCSitting
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Forced Vital Capacity (FVC) when patient is sitted.

pulmonaryFVCSittingPercentage
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Percentage of FVC sitting

pulmonaryMEP
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Expiratory Pressure (MEP) is the greatest amount of pressure that can be generated by exhaling against a mouthpiece, which is a measure of the strength of respiratory muscles. [Definition Source: NCI] (uom: CMH2O)

pulmonaryMEPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Expiratory Pressure (MEP) is the highest pressure that can be developed during a forceful expiratory effort against an occluded airway. It is usually measured at maximal inspiration and reported as a positive number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

pulmonaryMEPpercentage
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Percentage of MEP.

pulmonaryMIP
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Inspiratory Pressure (MIP) is the greatest amount of pressure that can be generated during inhalation against a fully occluded airway, which is used to measure the strength of respiratory muscles. [Definition Source: NCI]

pulmonaryMIPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Inspiratory Pressure (MIP) is the lowest pressure developed during a forceful inspiration against an occluded airway. It is usually measured at maximal expiration and recorded as a negative number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

pulmonaryMIPpercentage
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Percentage of MIP.

pulmonaryNIP
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Maximal Negative Inspiratory Pressure (NIP) measures the strength of the diaphragm and other muscles of inspiration and reflects the ability to maintain normal lung expansion and avoid atelectasis. [Definition Source: doi.org/10.1016/B978-032304841-5.50067-4 ]

pulmonaryPCF
type: DatatypeProperty
domain: Pulmonary Function Test
range: float
comment: Peak Cough Flow (PCF) is the maximum rate of air flow expelled through the mouth, endotracheal, or tracheostomy tube during a cough. [Definition Source: NCI]

pulmonaryPCO2
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The partial pressure of carbon dioxide (PCO2) is the concentration of carbon dioxide in the blood. This is a sensitive indication of the efficiency or level of ventilation of the lungs. [Definition Source: Collins Dictionary of Medicine]

pulmonaryPO2
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The partial pressure of oxigen (PO2) is the concentration of oxygen in the blood. This commonly measured parameter is an important indicator of the efficiency with which oxygen is transferred from atmosphere to blood. [Definition Source: Collins Dictionary of Medicine]

pulmonaryVCAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Vital capacity (VC) is the total volume of air that can be exhaled after inhaling as much as you can. [Definition Source: John Hopkins Medicine]

pyramidalEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for pyramidal functions.

pyramidalRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the pyramidal functions.

quadraticTrendHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The parameter corresponding to the curvature of heart rate.

questionnaireSubmitted
type: DatatypeProperty
domain: Questionnaire filled using a mobile application
range: dateTime
comment: When the questionnaire was submitted.

quotientAlbuminCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: CSF/serum albumin ratio is performed to understand the blood–CSF barrier disruption. [Defintion Source: Luque, Francisco A, and Stephen L Jaffe. “Cerebrospinal fluid analysis in multiple sclerosis.” International review of neurobiology vol. 79 (2007)]

r2HeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The quality of the quadratic model.

reasonIrregularCycle
type: DatatypeProperty
domain: Menstrual Cycle
range: PlainLiteral
comment: Why the patient has an irregular menstrual cycle.

reasonNoMenstrualCycle
type: DatatypeProperty
domain: Menstrual Cycle
range: PlainLiteral
comment: Why the patient has no menstrual cycle. (e.g., menopause)

reasonWalkTestNotCompleted
type: DatatypeProperty
domain: Walk Test
range: PlainLiteral
comment: The reason the walk test was not completed.

relapseClinicalTherapy
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required treatment in an ambulatory care clinic.

relapseCortisoneTherapy
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required a cortisone therapy.

relapseDuration
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: integer
comment: The number of days the relapse lasted.

relapseEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: date
comment: The calendar date of the end of the relapse.

relapseHospitalAdmission
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required an hospital admission.

relapseImpactOnADL
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse afftecd the Activity of Daily Living (ADL).

relapseRecovery
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: Datatype
  one of: complete
  one of: none
  one of: partial
comment: How much the patient recovered from the relapse.

relapseSequela
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the patient presented symptoms continuing in time, maybe less severe.

relapseSeverity
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: Datatype
  one of: life risk
  one of: moderate
  one of: serious
  one of: slight
comment: The severity of the relapse.

relapseStart
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: date
comment: The calendar date of the start of the relapse.

relativeEndDate
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: Privacy preserving end date computed according to an algorithm used to extract public instances.

relativeStartDate
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: Privacy preserving start date computed according to an algorithm used to extract public instances.

remSleep
type: DatatypeProperty
domain: Sleep Data
range: float
comment: REM sleep duration registered by the wearable device. [uom: seconds]

repirationSampEn
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The sample entropy

residenceEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Residence
range: gYear
comment: The calendar end date of the patient's residence in a specific geographical location.

residenceStart
type: DatatypeProperty
type: FunctionalProperty
domain: Residence
range: gYear
comment: The calendar start date of the patient's residence in a specific geographical location.

respirationAlpha1DimMean
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA. DimMean is the mean of singularity dimensions.

respirationAlpha1DimRange
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA. DimRange is the range of singularity dimensions, corresponding to the height of the singularity spectrum.

respirationAlpha1ExpMean
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA of short-term fluctuations. ExpMean is the mean of singularity exponents.

respirationAlpha1ExpRange
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA of short-term fluctuations. ExpRange is the range of singularity exponents, corresponding to the width of the singularity spectrum.

respirationAlpha2DimMean
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA. Dimmean is the mean of singularity dimensions.

respirationAlpha2DimRange
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA. DimRange is the range of singularity dimensions, corresponding to the height of the singularity spectrum.

respirationAlpha2ExpMean
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA of long-term fluctuations. ExpMean is the mean of singularity exponents.

respirationAlpha2ExpRange
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: Multifractal DFA of long-term fluctuations. ExpRange is the range of singularity exponents, corresponding to the width of the singularity spectrum.

respirationApEn
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The approximate entropy

respirationDFAalpha1
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The “short-term” fluctuation value generated from Detrended Fluctuation Analysis i.e. the root mean square deviation from the fitted trend of the breath-to-breath intervals. Will only be computed if there are more than 160 breath cycles in the respiratory rate.

respirationDFAalpha2
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The long-term fluctuation value. Will only be computed if there are more than 640 breath cycles in the respiratory rate.

respirationRMSSD
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The root mean square of successive differences of the breath-to-breath intervals.

respirationSD1
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: A measure of the spread of breath-to-breath intervals on the Poincaré plot perpendicular to the line of identity. It is an index of short-term variability.

respirationSD2
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: SD2 is a measure of the spread of breath-to-breath intervals on the Poincaré plot along the line of identity. It is an index of long-term variability.

respirationSD2SD1
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The ratio between short- and long-term fluctuations of the breath-to-breath intervals (SD2 divided by SD1).

respirationSDBB
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The standard deviation of the breath-to-breath intervals.

respirationSDSD
type: DatatypeProperty
domain: Respiratory Data
range: float
comment: The standard deviation of the successive differences between adjacent

respiratorySubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Respiratory ALSFRS subscore. Sum of items: 10, 11 and 12.

restStressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: Rest stress duration registered by the wearable device. [uom: seconds]

restingHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: Resting heart rate registered by the wearable device. [uom: bpm]

retiredAtDiagnosis
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: An indicator of whether the patient was retired at the time of diagnosis.

revisedALSFRS
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4296567
comment: Revised Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12.

sdmtCorrect
type: DatatypeProperty
domain: Symbol Digit Modalities Functional Test
range: integer
comment: Symbol Digital Modalities Test corrected.

sdmtIncorrect
type: DatatypeProperty
domain: Symbol Digit Modalities Functional Test
range: integer
comment: Symbol Digital Modalities Test raw score.

sensoryEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for sensory functions.

sensoryRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved sensory functions.

sex
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: Datatype
  one of: female
  one of: male
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522384
comment: The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. [Definition Source: NCI]

sexuality
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036915
comment: The feeling an individual has about their own sexual preferences and how those views are acted upon. [Definition Source: NCI]

slope
type: DatatypeProperty
domain: Patient
range: float
comment: The slope of the ALSFRS-R score between time-of-onset and Time 0 computed as: (48-ALSFRSR(Time0))/(Time0-TimeOnset)

smokersNumber
type: DatatypeProperty
domain: Smoking
range: int
comment: The number of smokers the patient lives or works with.

smokingExpositionType
type: DatatypeProperty
domain: Smoking
range: Datatype
  one of: Living with smokers
  one of: Smoker
  one of: Working with smokers
comment: Type of smoking exposition.

spinalCordLesions
type: DatatypeProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI showed spinal cord lesions.

spo2AOD100
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Cumulative area of desaturations under the 100% SpO2 level as baseline and normalized by the total recording time

spo2AODMax
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: The area under the oxygen desaturation event curve, using the maximum SpO2 value as baseline and normalized by the total recording time

spo2AV
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Average of the pulse oximetry.

spo2CA
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Integral SpO2 below the 90% SpO2 level normalized by the total recording time

spo2CT
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Percentage of the time spent below the 90% oxygen saturation level.

spo2DI
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Delta Index.

spo2M
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Percentage of the pulse oximetry 90% below median oxygen saturation.

spo2MED
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Median of the pulse oximetry.

spo2Min
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Minimum value of the pulse oximetry.

spo2ODI
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: The average number of desaturation events per hour (int).

spo2P
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Percentile (90th)

spo2POD
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Percentage of oxygen desaturation events

spo2RG
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: SpO2 range (difference between the max and min value).

spo2SD
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Standard deviation of the pulse oximetry.

spo2ZC
type: DatatypeProperty
domain: SPO2 Data
range: float
comment: Number of zero-crossing points.

stdHeartRate
type: DatatypeProperty
domain: Heart Rate Measurement
range: float
comment: The standard deviation of the heart rate after stimulus onset.

steps12am6am
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Total steps within the considered segment of data and between 12 AM and 6 AM daily

steps12pm6pm
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Total steps within the considered segment of data and between 12 PM and 6 PM

steps6am12pm
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Total steps within the considered segment of data and between 6 AM and 12 PM

stressDuration
type: DatatypeProperty
domain: Stress Level
range: float
comment: Stress duration registered by the wearable device. [uom: seconds]

stressQualifier
type: DatatypeProperty
domain: Stress Level
range: PlainLiteral
comment: Stress qualifier registered by the wearable device.

stroke
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a stroke.

sunExposure
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1456711
comment: The exposure to incident light from the sun. [Definition Source: NCI]

symptomClinicalName
type: DatatypeProperty
domain: Symptom
range: PlainLiteral
comment: The clinical name of the symptom.

symptomEnd
type: DatatypeProperty
domain: Symptom
range: dateTime
comment: When the symptom ended.

symptomGrade
type: DatatypeProperty
domain: Symptom
range: Datatype
  one of: Mild
  one of: Moderate
  one of: Severe
comment: The severity of the symptom.

symptomStart
type: DatatypeProperty
domain: Symptom
range: dateTime
comment: When the symptom started.

symptomType
type: DatatypeProperty
domain: Symptom
range: PlainLiteral
comment: Defines the symptom's category.

symptomValue
type: DatatypeProperty
domain: Symptom
range: float
comment: The numerical value associated with the symptom, e.g., the temperature fever.

thoracicSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic spine surgery.

thoracicSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic surgery.

thoracicTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic trauma.

thyroidDisorder
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a thyroid disorder.

totalCalories
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Sum of active and basal calories

totalLesionsT2MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: PlainLiteral
comment: The total number of lesions in T2 detected with the MRI.

totalSleepDuration
type: DatatypeProperty
domain: Sleep Data
range: float
comment: Total sleep duration registered by the wearable device. [uom: seconds]

traumaDate
type: DatatypeProperty
type: FunctionalProperty
domain: Trauma
range: date
comment: The calendar date in which the trauma occurred.

traumaDescription
type: DatatypeProperty
domain: Trauma
range: PlainLiteral
comment: A description of the trauma

unitOfMeasure
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: PlainLiteral
comment: The unit of measure of reference of the laboratory test result.

unmeasurableSleepDuration
type: DatatypeProperty
domain: Sleep Data
range: float
comment: Unmeasurable sleep duration registered by the wearable device. [uom: seconds]

upperLimbSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an upper limb surgery.

validMeasurements
type: DatatypeProperty
domain: Class
  union of: Air pollution concentration
  union of: Weather Data
range: integer
comment: For each recorded variable, number of valid measurements in that week, ranging from 0 to 7.

vigorousIntensityDuration
type: DatatypeProperty
domain: Physical Activity Data
range: float
comment: Vigorous intensity duration registered by the wearable device. [uom: seconds]

virusJCTestedCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: boolean
comment: Whether the presence of JC virus was tested in the CSF specimen.

visualAcuityLeft
type: DatatypeProperty
domain: Visual Acuity
range: integer
comment: Visual Acuity Test on the left eye.

visualAcuityRight
type: DatatypeProperty
domain: Visual Acuity
range: integer
comment: Visual Acuity Test on the right eye.

visualEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for visual (optic) functions.

visualEvokedPotentialAmplitude
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: float
comment: The amplitude for the Visual Evoked Potential (VEP) wave. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [uV].
note: This data property can only be used for Evoked Potential of type 'visual'.

visualEvokedPotentialLatency
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: integer
comment: The average peak latency for the Visual Evoked Potential (VEP) wave at approximately 100 ms following stimulus onset. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [microsec].
note: This data property can only be used for Evoked Potential of type 'visual'.

visualRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved visual functions.

walkAssistiveDevice
type: DatatypeProperty
domain: Walk Test
range: boolean
comment: Whether the patient uses an assistive device for walking.

walkAssistiveDeviceUsed
type: DatatypeProperty
domain: Walk Test
range: PlainLiteral
comment: The type of assistive device used for walking.

walkTestNotCompleted
type: DatatypeProperty
domain: Walk Test
range: boolean
comment: Whether the walk test was completed.

walkingTime10Meters
type: DatatypeProperty
domain: Walk Test ALS
range: float
comment: Time to walk 10 meters.

walkingTime25Steps
type: DatatypeProperty
domain: Walk Test MS
range: float
comment: Time to take 25 steps.

wearableDataMeasurementDuration
type: DatatypeProperty
domain: Wearable Data Measurement
range: integer
comment: The duration of the measurement.

wearableDataMeasurementStartTime
type: DatatypeProperty
domain: Wearable Data Measurement
range: dateTime
comment: The timestamp in which the measurement started.

weeklyFrequency
type: DatatypeProperty
domain: Physical Activity
range: float
comment: The number of hours per week physical activity takes place.

weight
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005910
comment: Measurement of quantity by means of weighing; quantity (in the abstract) as determined in this way. [Definition Source: Oxford English Dictionary]

whoThresholdExceeded
type: DatatypeProperty
domain: Air pollution concentration
range: integer
comment: Number of days spent over the respective World Health Organization (WHO) threshold in that week (computed as following); if there are no valid measurements in that week, it is denoted as NA. * For Carbon Monoxide (CO): if CO ≤ 4 mg/m3 then the value is 0; otherwise, it is 1 * For Nitrogen Dioxide (NO 2 ): if NO 2 ≤ 25 µg/m3 then the value is 0; otherwise, it is 1 * For Ozone (O3): if O 3 ≤ 100 µg/m3 then the value is 0; otherwise, it is 1 * For Particulate Matter with a diameter of 2.5 micrometers or smaller (PM 2.5): if PM 2.5 ≤ 15 µg/m 3 then the value is 0; otherwise, it is 1 * For Particulate Matter with a diameter of 10 micrometers or smaller (PM 10 ): if PM 10 ≤ 45 µg/m3 , then the value is 0; otherwise, it is 1 * For Sulfur Dioxide (SO 2 ); if SO 2 ≤ 40 µg/m3 , then the value is 0; otherwise, it is 1

zipCode
type: DatatypeProperty
type: FunctionalProperty
domain: Place
range: PlainLiteral
comment: A group of letters or numbers, or both, added to a postal address to facilitate the sorting and delivery of mail. Later also: the area designated by such a code. [Definition Source: Oxford English Dictionary]

zipHashed
type: DatatypeProperty
type: FunctionalProperty
domain: Place
range: PlainLiteral
comment: The zip code hashed for privacy reasons.

Person
type: Class
comment: A human being. [Definition Source: NCI]

ALS Brainteaser Comorbidities
type: Class
subclass of: Use-Case Comorbidities
comment: Comorbidities checked for ALS patient in the BRAINTEASER study.

Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
type: Class
subclass of: Questionnaire
comment: The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is an instrument for evaluating the functional status of patients with Amyotrophic Lateral Sclerosis. It can be used to monitor functional change in a patient over time. [Definition Source: Georgetown University Hospital - Medstar Health]

Activity
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0441655
comment: An active process; excludes processes and mechanisms which fulfill biological functions. [Definition Source: NCI]
note: In our data we refer to it as "Behaviour".

Administration
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1533734
comment: The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine. [Definition Source: NCI]

Adverse Drug Reaction
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0041755
comment: Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCI]

Anatomic Site
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1515974
comment: Named locations of or within the body. [Definition Source: NCI]

Questionnaire filled using a mobile application
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034394
comment: A predetermined set of questions. [Definition Source: NCI]

Atmospheric Pressure
type: Class
subclass of: Weather Data
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004180
comment: The pressure at any point in an atmosphere due solely to the weight of the atmospheric gases bove the point concerned. [Definition Source: MSH]

Daily Average Relative Humidity
type: Class
subclass of: Humidity

Daily Average Sea Level Pressure
type: Class
subclass of: Atmospheric Pressure

Awaji Clinical Evaluation
type: Class
subclass of: Diagnostic Procedure
comment: Diagnostic assessment of ALS following the Awaji reccomendations (doi.org/10.1016/j.clinph.2007.09.143).

Brief Visuospatial Memory Test-Revised
type: Class
subclass of: Cognitive Assessment
comment: The BVMT-R measures Visuospatial Memory for Patients with Head Trauma, LD, Psychiatric Disorder, and Mixed Diagnoses. [Source: https://www.parinc.com/Products/Pkey/30#:~:text=A%20Measure%20of%20Visuospatial%20Memory,to%20document%20changes%20over%20time.]

Beat-To-Beat Data
type: Class
subclass of: Wearable Data Measurement
comment: Beat-To-Beat Data registered by a wearable device.

Before Onset
type: Class
subclass of: Event
comment: Any event that happened to a patient before the onset.

Benzene concentration
type: Class
subclass of: Air pollution concentration

Carbon Monoxide concentration
type: Class
subclass of: Air pollution concentration
comment: The determination of the amount of carbon monoxide present in a sample. [Definition Source: NCI]

CSF Analysis
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2026522
comment: A laboratory analysis of a sample of cerebrospinal fluid. [Definition Source: NCI]

California Verbal Learning Test - Second Edition
type: Class
subclass of: Cognitive Assessment
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3899729
comment: The second version of California Verbal Learning Test, a neuropsychological test developed to make a comprehensive and detailed assessment of verbal learning and memory in individuals ranging in age from 16 to 89 years. [Definition Source: NCI]

Clinical Evaluation
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1261322
comment: An assessment of an individual's physical, mental, or emotional condition; information can be gathered from multiple sources, including physical exam, personal interview and observation, medical history, laboratory and imaging tests. [Definition Source: NCI]

Clinical Trial
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008976
comment: A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. [Definition Source: NCI]

Clinical Trial Participation
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4041024
comment: The participation in a clinical trial

Clinics and Hospitals
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0587906
comment: Institutions with an organized medical staff for the medical care, treatment, and cure of the sick and wounded, for the study of disease, and for the training of physicians, nurses, and allied health personnel. [Definition Source: NCI]

Cognitive Assessment
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0870300
comment: The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. [Definition Source: NCI]

Comorbidity
type: Class
subclass of: Condition
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009488
comment: The coexistence of two or more disease processes. [Definition Source: NCI]

Condition
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0348080
comment: A state of being, such as a state of health. [Definition Source: NCI]

Dysphagia In Multiple Sclerosis
type: Class
subclass of: Questionnaire filled using a mobile application
comment: A questionnaire to assess dysphagia in MS patients [DOI: 10.1016/j.jns.2007.12.021]

Diagnosis
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011900
comment: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. [Definition Source: NCI]

Diagnostic Imaging
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011923
comment: Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. [Definition Source: NCI]

Diagnostic Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0430022
comment: Any procedure or test to diagnose a disease or disorder. [Definition Source: NCI]

Disease, Disorder or Finding
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1511989
comment: A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions. [Definition Source: NCI]

Edinburgh Cognitive and Behavioural ALS Screen
type: Class
subclass of: Cognitive Assessment
comment: The ECAS is a brief multidomain assessment originally designed for people with Amyotrophic Lateral Sclerosis (ALS/Motor Neurone Disease) but is also useful in other neurodegenerative disorders. [Source: https://ecas.psy.ed.ac.uk/]

Expanded Disability Status Scale (EDSS)
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0451246
comment: A system for quantifying disability in multiple sclerosis (MS). Based on a standard neurological examination, the Expanded Disability Status Scale quantifies disability in seven Functional Systems (plus "Other") and assigns a Functional System Score in each. Results are ranked as steps from 0 to 10, with steps 1 through 4.5 describing MS patients who are fully ambulatory and steps 5 through 9.5 describing increasing impairment to ambulation. Step 10 refers to death due to MS. [Definition Source: NCI]

European Quality of Life Five Dimension Five Level Scale Questionnaire
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3640517
comment: A standardized rating scale which is used as a measure of health outcome. This instrument is a descriptive system consisting of 5 dimensions: mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Each dimension has 5 levels ranging from no problem to extreme problem or incapable, which are assessed by the patient. [Definition Source: NCI]

End Therapy Reason
type: Class
comment: The motivation for the interruption of the therapeutic treatment.

Event
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0441471
comment: Something that happens at a given place and time. [Definition Source: NCI]

Evoked Potentials
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015214
comment: Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. [Definition Source: MSH]

Gene
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017337
comment: A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCI]

Genetic Testing
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0679560
comment: The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. [Definition Source: NCI]

Global Radiation
type: Class
subclass of: Weather Data

Gold Coast Diagnosis Criteria
type: Class
subclass of: Diagnostic Procedure
comment: Diagnostic assessment of ALS following the Gold Coast criteria (doi.org/10.1136/practneurol-2021-003256 ).

Group (social concept)
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1257890
comment: A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender) [Definition Source: NCI]

Hospital Anxiety and Depression Scale
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3539657
comment: A standardized survey developed and copyrighted by A. S. Zigmond and R. P. Snaith in 1983, 1992, 1994 and published in the Acta Psychiatrica Scandinavica journal (A.S. Zigmond and R.P. Snaith. The Hospital Anxiety and Depression Scale. Acta psychiart. scand. 1983, 67:361-370) which is used to detect depression and anxiety in individuals in a hospital or medical outpatient clinic. This instrument is a self-administered questionnaire consisting of 14 items that assess how the individual has felt over the past week. Each item as 4 response options that are associated with a score of 0 to 3. [Definition Source: NCI]

Hospital Anxiety and Depression Scale for ALS patients
type: Class
subclass of: Hospital Anxiety and Depression Scale
comment: Hospital Anxiety and Depression Scale questionnaire administered to ALS patients.

Hand Dexterity
type: Class
subclass of: Diagnostic Procedure
comment: Test performed to assess the ability of a person to use the fingers, hands and arms to perform a task. [Definition Source: physio-pedia.com]

Heart Rate Measurement
type: Class
subclass of: Wearable Data Measurement
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018810
comment: The number of heartbeats per unit of time, usually expressed as beats per minute. [Definition Source: NCI]

Hematology Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0200627
comment: A laboratory test to measure hematopoietic components and investigate hematologic disorders in a blood sample. [Definition Source: NCI]

Humidity
type: Class
subclass of: Weather Data
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020167
comment: A measure of the water vapor content of air. [Definition Source: NCI]

Impairment
type: Class
subclass of: Condition
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0221099
comment: Loss or abnormality of psychological, physiological, or anatomic structure or function. [Definition Source: NCI]

Intervention or Procedure
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0184661
comment: An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. [Definition Source: NCI]

King's Clinical Staging Method
type: Class
subclass of: Questionnaire
comment: The King’s staging system consists of five disease stages, with Stage 5 being death. Stages 1–3 are based upon the number of El Escorial central nervous system (CNS) regions involved in the disease, measured by weakness, wasting, spasticity, dysphagia, or dysarthria. Stage 4 is nutritional failure, defined by the requirement for gastrostomy, or respiratory failure, defined by the requirement for noninvasive ventilation (NIV), and based upon the National Institute for Clinical Excellence MND Guidelines (Supplemental Material). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]

Kinship
type: Class
comment: The relationship between members of the same family. [Cambridge Dictionary]
note: This class is always instantiated as a blank node

KinshipType
type: Class
comment: The type of the relationship between members of the same family.
note: For the purpose of our ontology, we only consider biological kinship. We omit the word "biological" from the invidual's labels, for example "father" refers to "biological father".

Laboratory Test Result
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0587081
comment: The outcome of a laboratory test. [Definition Source: NCI]

Last 5 Years Event
type: Class
subclass of: Before Onset
comment: Events occurred in the last 5 years (from the first visit).

Lifestyle
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023676
comment: A manner of living that reflects the person's values and attitudes. [Definition Source: NCI]

Modified Fatigue Impact Scale
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3810705
comment: A standardized rating scale developed by Fisk et al in 1994, which assesses how fatigue may affect a person and the impact of fatigue on quality of life. The questionnaire contains 21 questions which are scored ranging from 0 (never) to 4 (almost always). [Definition Source: NCI]

Magnetic Resonance Imaging (MRI)
type: Class
subclass of: Diagnostic Imaging
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024485
comment: Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. [Definition Source: NCI]

MSQOL54 Multiple Sclerosis Quality of Life (MSQOL)-54 Instrument
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3826975
comment: A standardized rating scale developed by Vickrey et al in 1995 and 1997, which combines items that are generic and disease-specific to assess quality of life and the level of physical, emotional, and cognitive functions in patients with multiple sclerosis. The questionnaire contains 54 questions and generates 12 subscales: physical function, role limitations due to physical problems, role limitations due to emotional problems, pain, emotional well-being, energy, health perceptions, social function, cognitive function, health distress, sexual function and overall quality of life. [Definition Source: NCI]

Daily Maximum Temperature
type: Class
subclass of: Temperature

Daily Mean Global Radiation
type: Class
subclass of: Global Radiation

Daily Mean Temperature
type: Class
subclass of: Temperature

Daily Mean Wind Speed
type: Class
subclass of: Wind Speed

Menstrual Cycle
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025329
comment: The Menstrual Cycle involves regularly recurring hormonal changes and physiologic endometrial changes during the reproductive period in human females, and some primates, and culminates in partial sloughing of the endometrium (menstruation) in the absence of fertilization. For most women, one cycle takes 28 days. [Definition Source: NCI]

Milano-Torino Functional Staging System (MiToS)
type: Class
subclass of: Questionnaire
comment: The Milano–Torino (MiToS) Staging system comprises six stages, based on functional impairment as assessed by the revised ALS Functional Rating Scale (ALSFRS-R). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]

Daily Minimum Temperature
type: Class
subclass of: Temperature

More Than 5 Years Event
type: Class
subclass of: Before Onset
comment: Events occured more than 5 years ago, counting from the first visit.

Muscle Tone ALS
type: Class
subclass of: MuscleTone
comment: Muscle tone assessment performed to ALS patients.

Muscle Tone Assessment
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4707572
comment: Muscle Tone measured by the modified Ashworth scale. The modified Ashworth scale is a muscle tone assessment scale used to assess the resistance experienced during passive range of motion, which does not require any instrumentation and is quick to perform. [Source: ncbi.nlm.nih.gov/books/NBK554572/]

Muscle Tone MS
type: Class
subclass of: MuscleTone
comment: Muscle tone assessment performed to MS patients.

Occupation
type: Class
comment: The principal activity that a person does to earn money. [Definition Source: NCI]

Oligoclonal Bands
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4048246
comment: The presence of more than one immunoglobulin band in the serum, urine, or cerebrospinal fluid. It usually results from infectious or immunologic disorders. [Definition Source: NCI]

Onset
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0332162
comment: The start, beginning, or early stages. [Definition Source: NCI]

Positron Emission Tomography (PET)
type: Class
subclass of: Diagnostic Imaging
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032743
comment: A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered. [Definition Source: NCI]

Pulmonary function testing
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024119
comment: A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]

Particulate Matter <1 µm concentration
type: Class
subclass of: Air pollution concentration

Pittsburgh Sleep Quality Index
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3697468
comment: A self-rated questionnaire which assesses sleep quality and disturbances over a one month time interval. [Definition Source: NCI]

Patient
type: Class
subclass of: Person
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030705
comment: A person who receives medical attention, care, or treatment, or who is registered with medical professional or institution with the purpose to receive medical care when necessary. [Definition Source: NCI]

Pharmacologic Substance
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1254351
comment: Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCI]

Physical Activity
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026606
comment: Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI][attribution: from NIDDK Glossary; http://www.niddk.nih.gov/health/nutrit/pubs/glossary/glossaryintro.htm]

Physical Activity Data
type: Class
subclass of: Wearable Data Measurement
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026606
comment: Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI]

Place
type: Class
comment: A particular part or region of space; a physical locality, a locale; a spot, a location. [Definition Source: Oxford English Dictionary]

Precipitation
type: Class
subclass of: Weather Data

Daily Precipitation Sum
type: Class
subclass of: Precipitation

Pregnancy
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032961
comment: The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [Definition Source: NCI]

Protocol Event
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2698908
comment: Other important events that occur during a trial but are not driven by protocol requirements. [Definition Source: NCI]

Pulmonary Function Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024119
comment: A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]

Questionnaire
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034394
comment: A predetermined set of questions. [Definition Source: NCI]

Relapse
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0277556
comment: The return of a disease after a period of remission. [Definition Source: NCI]

Residence
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0237096
comment: Any address at which a person dwells more than temporarily. [Definition Source: NCI]

Respiratory Data
type: Class
subclass of: Wearable Data Measurement
comment: Respiratory Data registered by a wearable device.

Symbol Digit Modalities Functional Test
type: Class
subclass of: Cognitive Assessment
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3891405
comment: A standardized rating scale developed by Aaron Smith in 1982, which is used to identify individuals with neurological impairment, as well as to assess divided attention, visual scanning and motor speed. This functional test measures the time to pair abstract symbols with specific numbers with a 90 second time limit. Scoring of this test is based on the total number of correctly coded items from 0-110 in 90 seconds. [Definition Source: NCI]

Sleep Quality
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5420463
comment: A question about an individual's sleeping. [Definition Source: NCI]

SPO2 Data
type: Class
subclass of: Wearable Data Measurement
comment: SPO2 Data registered by a wearable device.

Self assessed ALSFRS-R questionnaire
type: Class
subclass of: Questionnaire filled using a mobile application
comment: ALSFRS-R assessed by the patient using the mobile questionnaires.

Sleep Data
type: Class
subclass of: Wearable Data Measurement
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037313
comment: A natural and periodic state of rest during which consciousness of the world is suspended. [Definition Source: NCI]

Smoking
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037369
comment: The act of puffing and/or inhaling the combustion products of a substance so as to be tasted and absorbed into the bloodstream. [Definition Source: NCI]

Stress Level
type: Class
subclass of: Wearable Data Measurement
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0038435
comment: The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [Definition Source: NCI]

Surgical Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0543467
comment: A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. [Definition Source: NCI]

Surgical Procedure Type
type: Class
comment: It defines some type of surgical procedures a patient could undergo.

Symptom
type: Class
subclass of: Condition
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1457887
comment: Subjective evidence of disease perceived by the patient. [Definition Source: NCI]

Temperature
type: Class
subclass of: Weather Data
comment: The temperature of the surroundings. [Definition Source: NCI]

Therapeutic Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0087111
comment: An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. [Definition Source: NCI]

Therapeutic Procedure Type
type: Class
comment: It defines some type of therapeutic procedures that could be administered to a patient.

Therapeutic Treatment
type: Class
comment: The therapeutic treatment that has been administered to a patient.

Trauma
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3263723
comment: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]

Use-Case Comorbidities
type: Class
subclass of: Comorbidity
comment: Comorbidities checked in a specific use-case, e.g. ALS patients in a specific study.

Visual Analogue Scale
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3536884
comment: A psychometric response scale to assess subjective characteristics or symptoms, which relies upon a continuum of possible result values in between two fixed end-points. [Definition Source: NCI]

Visual Analogue Scale for ALS patients
type: Class
subclass of: Visual Analogue Scale
comment: Visual Analogue Scale questionnaire administered to ALS patients.

Volatile Organic Compound concentration
type: Class
subclass of: Air pollution concentration

Visual Acuity
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042812
comment: Sharpness of vision, the ability to discern fine detail. [Definition Source: NCI]

Weight
type: Class
subclass of: Questionnaire filled using a mobile application
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005910
comment: The weight of a subject. [Definition Source: NCI]

Walk Test
type: Class
subclass of: Diagnostic Procedure
comment: Test performed to assess the walking abilities of patients.

Walk Test ALS
type: Class
subclass of: Walk Test
comment: Walk test performed to ALS patients.

Walk Test MS
type: Class
subclass of: Walk Test
comment: Walk test performed to MS patients.

Wearable Data Measurement
type: Class
subclass of: Activity
comment: Measurements collected by wearables.

Weather Data
type: Class
subclass of: Quantity
subclass of: Restriction
  on property: isProducedBy
  qualified cardinality: 1
  on class: SensingDevice
comment: The different weather information registered by sensing devices.

Wind Speed
type: Class
subclass of: Weather Data

Armed forces occupations
type: NamedIndividual
type: Concept
type: Occupation
comment: Armed forces occupations include all jobs held by members of the armed forces. Members of the armed forces are those personnel who are currently serving in the armed forces, including auxiliary services, whether on a voluntary or compulsory basis, and who are not free to accept civilian employment and are subject to military discipline. Included are regular members of the army, navy, air force and other military services, as well as conscripts enrolled for military training or other service for a specified period. Occupations in this major group are classified into the following sub-major groups: 01 Commissioned Armed Forces Officers 02 Non-commissioned Armed Forces Officers 03 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.

Commissioned armed forces officers
type: NamedIndividual
type: Concept
type: Occupation
comment: Commissioned armed forces officers provide leadership and management to organizational units in the armed forces and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes all members of the armed forces holding the rank of second lieutenant (or equivalent) or higher. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 011 Commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
broader transitive: Armed forces occupations

Non-commissioned armed forces officers
type: NamedIndividual
type: Concept
type: Occupation
comment: Non-commissioned armed forces officers enforce military discipline and supervise the activities of those employed in Sub-major Group 03: Armed Forces Occupations, Other Ranks, and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes members of the armed forces holding ranks such as sergeant, warrant officer and sergeant major. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 021 Non-commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
broader transitive: Armed forces occupations

Armed forces occupations, other ranks
type: NamedIndividual
type: Concept
type: Occupation
comment: Armed forces occupations, other ranks include all conscripted and non-conscripted members of the armed forces except commissioned and non-commissioned officers. They perform specific military tasks and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. Most occupations in this sub-major group require skills at the first ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 031 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
broader transitive: Armed forces occupations

Managers
type: NamedIndividual
type: Concept
type: Occupation
comment: Managers plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations, or of organizational units within them, and formulate and review their policies, laws, rules and regulations. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level, except for Sub-major Group 14: Hospitality, Retail and Other Services Managers, for which skills at the third ISCO skill level are generally required. Tasks performed by managers usually include: formulating and advising on the policy, budgets, laws and regulations of enterprises, governments and other organizational units; establishing objectives and standards and formulating and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise and of its staff; selecting or approving the selection of staff; ensuring compliance with health and safety requirements; planning and directing daily operations; representing and negotiating on behalf of the government, enterprise or organizational unit managed in meetings and other forums. Occupations in this major group are classified into the following sub-major groups: 11 Chief Executives, Senior Officials and Legislators 12 Administrative and Commercial Managers 13 Production and Specialized Services Managers 14 Hospitality, Retail and Other Services Managers

Chief executives, senior officials and legislators
type: NamedIndividual
type: Concept
type: Occupation
comment: Chief executives, senior officials and legislators formulate and review the policies, and plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations with the support of other managers. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level . Tasks performed by workers in this sub-major group usually include: presiding over or participating in the proceedings of legislative bodies, boards of directors and committees; formulating and advising on the policy budgets, laws and regulations of enterprises, governments and other organizations; establishing objectives for enterprises, government departments or agencies and other organizations; formulating or approving and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise; selecting or approving the selection of senior staff; performing ceremonial duties and representing the enterprise, government, organization or community at official occasions and in meetings, negotiations, conventions and public hearings. Occupations in this sub-major group are classified into the following minor groups: 111 Legislators and Senior Officials 112 Managing Directors and Chief Executives
broader transitive: Managers

Administrative and commercial managers
type: NamedIndividual
type: Concept
type: Occupation
comment: Administrative and commercial managers plan, organize, direct, control and coordinate the financial, administrative, human resource, policy, planning, research and development, advertising, public relations, and sales and marketing activities of enterprises and organizations, or of enterprises that provide such services to other enterprises and organizations. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level Tasks performed by workers in this sub-major group usually include: formulating and administering policy advice and strategic and financial planning; establishing and directing operational and administrative procedures; implementing, monitoring and evaluating strategies and policies; providing advice to senior managers; directing the development of initiatives for new products, marketing, public relations and advertising campaigns; determining and directing sales activities, product mix and customer service standards; setting prices and credit arrangements; ensuring compliance with relevant legislation, regulations and standards; controlling selection, training and performance of staff; preparing budgets and overseeing financial operations; consulting with the chief executive and with managers of other departments or sections; controlling expenditure and ensuring the efficient use of resources; representing the enterprise or organization in negotiations, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 121 Business Services and Administration Managers 122 Sales, Marketing and Development Managers
broader transitive: Managers

Production and specialised services managers
type: NamedIndividual
type: Concept
type: Occupation
comment: Production and specialized services managers plan, direct and coordinate the production of the goods and the provision of the specialized professional and technical services provided by an enterprise or organization, either as the manager of a department or as the general manager of an enterprise or organization that does not have a hierarchy of managers. They are responsible for manufacturing, mining, construction, logistics, information and communications technology operations for large-scale agricultural, forestry and fisheries operations, and for the provision of health, education, social welfare, banking, insurance and other professional and technical services. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning details of activities in terms of output, services provided, quality, quantity, cost, timeliness and labour requirements; setting standards and objectives; controlling the operation of plant and of procedures; assuring quality of the goods produced and services provided; preparing tenders and contract bids; establishing and managing budgets, monitoring costs, and adjusting activities, procedures and resources to minimize costs; overseeing the acquisition and installation of new plant and equipment; coordinating the implementation of health and safety requirements; planning and directing daily operations; overseeing the selection, training and performance of staff; preparing, or arranging for the preparation of, reports, budgets and forecasts; representing the enterprise or organization in negotiations with other agencies, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 131 Production Managers in Agriculture, Forestry and Fisheries 132 Manufacturing, Mining, Construction and Distribution Managers 133 Information and Communica…
broader transitive: Managers

Hospitality, retail and other services managers
type: NamedIndividual
type: Concept
type: Occupation
comment: Hospitality, retail and other services managers plan, organize and direct the operations of establishments which provide accommodation, hospitality, retail and other services. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning and organizing special functions, sporting, gaming and entertainment activities and the range and mix of products, stock levels and service standards; promoting and selling goods and services; observing liquor, gaming, health and other laws and regulations; developing and reviewing policies, programmes and procedures concerning customer relations and goods and services provided; promoting facilities for conferences, conventions and trade shows to potential customers; organizing the purchase and maintenance of transport vehicles, equipment and fuel, and transporting goods; controlling the selection, training and supervision of staff; ensuring compliance with occupational health and safety regulations. Occupations in this sub-major group are classified into the following minor groups: 141 Hotel and Restaurant Managers 142 Retail and Wholesale Trade Managers 143 Other Services Managers
broader transitive: Managers

Professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Professionals increase the existing stock of knowledge; apply scientific or artistic concepts and theories; teach about the foregoing in a systematic manner; or engage in any combination of these activities. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level. Tasks performed by professionals usually include: conducting analysis and research, and developing concepts, theories and operational methods; advising on or applying existing knowledge related to physical sciences, mathematics, engineering and technology, life sciences, medical and health services, social sciences and humanities; teaching the theory and practice of one or more disciplines at different educational levels; teaching and educating persons with learning difficulties or special needs; providing various business, legal and social services; creating and performing works of art; providing spiritual guidance; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 21 Science and Engineering Professionals 22 Health Professionals 23 Teaching Professionals 24 Business and Administration Professionals 25 Information and Communications Technology Professionals 26 Legal, Social and Cultural Professionals

Science and engineering professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Science and engineering professionals conduct research; improve or develop concepts, theories and operational methods; or apply scientific knowledge relating to fields such as physics, astronomy, meteorology, chemistry, geophysics, geology, biology, ecology, pharmacology, medicine, mathematics, statistics, architecture, engineering, design and technology. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research, enlarging, advising on or applying scientific knowledge obtained through the study of structures and properties of physical matter and phenomena, chemical characteristics and processes of various substances, materials and products, all forms of human, animal and plant life and of mathematical and statistical concepts and methods; advising on, designing and directing construction of buildings, towns and traffic systems, or civil engineering and industrial structures, as well as machines and other equipment; advising on and applying mining methods and ensuring their optimum use; surveying land and sea and making maps; studying and advising on technological aspects of particular materials, products and processes, and on efficiency of production and work organization; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 211 Physical and Earth Science Professionals 212 Mathematicians, Actuaries and Statisticians 213 Life Science Professionals 214 Engineering Professionals (excluding Electrotechnology) 215 Electrotechnology Engineers 216 Architects, Planners, Surveyors and Designers
broader transitive: Professionals

Health professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Health professionals conduct research,; improve or develop concepts, theories and operational methods; and apply scientific knowledge relating to medicine, nursing, dentistry, veterinary medicine, pharmacy, and promotion of health. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research and obtaining scientific knowledge through the study of human and animal disorders and illnesses and ways of treating them; advising on or applying preventive and curative measures, or promoting health; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 221 Medical Doctors 222 Nursing and Midwifery Professionals 223 Traditional and Complementary Medicine Professionals 224 Paramedical Practitioners 225 Veterinarians 226 Other Health Professionals
broader transitive: Professionals

Teaching professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Teaching professionals teach the theory and practice of one or more disciplines at different educational levels; conduct research; improve or develop concepts, theories and operational methods pertaining to their particular discipline; and prepare scholarly papers and books. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting classes, courses, or tutorials at a particular educational level for educational and vocational purposes, including private lessons; conducting adult literacy programmes; teaching and educating persons with learning difficulties or special needs; designing and modifying curricula; inspecting and advising on teaching methods and aids; participating in decisions concerning the organization of teaching and related activities at schools and universities; conducting research in particular subjects to improve or develop concepts, theories or operational methods for application in industrial and other fields; preparing scholarly papers and books. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 231 University and Higher Education Teachers 232 Vocational Education Teachers 233 Secondary Education Teachers 234 Primary School and Early Childhood Teachers 235 Other Teaching Professionals
broader transitive: Professionals

Business and administration professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Business and administration professionals perform analytical, conceptual and practical tasks to provide services in financial matters, human resource development, public relations, marketing and sales in the technical, medical, information and communications technology areas; and conduct reviews of organizational structures, methods and systems as well as quantitative analyses of information affecting investment programmes. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, analysing and interpreting information on the financial viability, cost structures and trading effectiveness of organizations; conducting audits, preparing financial statements and controlling treasury systems for organizations; developing and reviewing financial plans and strategies, executing buy and sell orders, and negotiating the purchase and sale of commodities; developing, implementing and evaluating staff recruitment, training and development programmes; researching, developing and implementing marketing and public relations campaigns; studying and developing methods and policies to improve and promote government and business operations and effectiveness; acquiring and updating knowledge of employers’ and competitors’ goods and services, and of market conditions; assessing customers’ needs and explaining and demonstrating goods and services to them. Occupations in this sub-major group are classified into the following minor group: 241 Finance Professionals 242 Administration Professionals 243 Sales, Marketing and Public Relations Professionals
broader transitive: Professionals

Information and communications technology professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Information and communications technology professionals conduct research; plan, design, write, test, provide advice and improve information technology systems, hardware, software and related concepts for specific applications; develop associated documentation including principles, policies and procedures; and design, develop, control, maintain and support databases and other information systems to ensure optimal performance and data integrity and security. Tasks performed by workers in this sub-major group usually include: researching information technology use in business functions; identifying areas for improvement and researching the theoretical aspects and operational methods for the use of computers; evaluating, planning and designing hardware or software configurations for specific applications including for Internet, Intranet and multimedia systems; designing, writing, testing and maintaining computer programs; designing and developing database architecture and database management systems; developing and implementing security plans and data administration policy, and administering computer networks and related computing environments; analysing, developing, interpreting and evaluating complex system design and architecture specifications, data models and diagrams in the development, configuration and integration of computer systems. Occupations in this sub-major group are classified into the following minor groups: 251 Software and Applications Developers and Analysts 252 Database and Network Professionals
broader transitive: Professionals

Legal, social and cultural professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Legal, social and cultural professionals conduct research; improve or develop concepts, theories and operational methods; or apply knowledge relating to the law, storage and retrieval of information and artefacts, psychology, social welfare, politics, economics, history, religion, languages, sociology, other social sciences, and arts and entertainment. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research on legal problems; drafting laws and regulations; advising clients on legal cases; pleading and conducting cases in a court of law; presiding over judicial proceedings in a court of law; developing and maintaining library and gallery collections of archives; conducting research, improving or developing concepts, theories and operational methods or applying knowledge relating to the field of social sciences; conceiving, creating and performing in literary and artistic works; interpreting and communicating news, ideas, impressions and facts. Occupations in this sub-major group are classified into the following minor groups: 261 Legal Professionals 262 Librarians, Archivists and Curators 263 Social and Religious Professionals 264 Authors, Journalists and Linguists 265 Creative and Performing Artists
broader transitive: Professionals

Technicians and associate professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Technicians and associate professionals perform technical and related tasks connected with research and the application of scientific or artistic concepts and operational methods, and government or business regulations. Competent performance in most occupations in this major group requires skills at the third ISCO skill level. Tasks performed by technicians and associate professionals usually include: undertaking and carrying out technical work connected with research and the application of concepts and operational methods in the fields of physical sciences including engineering and technology, life sciences including the medical profession, and social sciences and humanities; initiating and carrying out various technical services related to trade, finance and administration including administration of government laws and regulations, and to social work; providing technical support for the arts and entertainment; participating in sporting activities; executing some religious tasks. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 31 Science and Engineering Associate Professionals 32 Health Associate Professionals 33 Business and Administration Associate Professionals 34 Legal, Social, Cultural and Related Associate Professionals 35 Information and Communications Technicians

Science and engineering associate professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Science and engineering associate professionals perform technical tasks connected with research and operational methods in science and engineering. They supervise and control technical and operational aspects of mining, manufacturing, construction and other engineering operations, and operate technical equipment including aircraft and ships. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: setting up, monitoring and operating instruments and equipment, conducting and monitoring experiments and tests of systems; collecting and testing samples; recording observations and analysing data; preparing, revising and interpreting technical drawings and diagrams; coordinating, supervising, controlling and scheduling the activities of other workers; operating and monitoring switchboards, computerized control systems, and multi-function process control machinery; performing technical functions to ensure safe and efficient movement and operations in ships, aircraft and other equipment. Occupations in this sub-major group are classified into the following minor groups: 311 Physical and Engineering Science Technicians 312 Mining, Manufacturing and Construction Supervisors 313 Process Control Technicians 314 Life Science Technicians and Related Associate Professionals 315 Ship and Aircraft Controllers and Technicians
broader transitive: Technicians and associate professionals

Health associate professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Health associate professionals perform technical and practical tasks to support diagnosis and treatment of illness, disease, injuries and impairments in humans and animals, and to support implementation of health care, treatment and referral plans usually established by medical, veterinary, nursing and other health professionals. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in the sub-major group usually include: testing and operating medical imaging equipment and administering radiation therapy; performing clinical tests on specimens of bodily fluids and tissues; preparing medications and other pharmaceutical compounds under the guidance of pharmacists; designing, fitting, servicing and repairing medical and dental devices and appliances; providing nursing and personal care and midwifery support services; using herbal and other therapies based on theories, beliefs and experiences originating in specific cultures. Occupations in this sub-major group are classified into the following minor groups: 321 Medical and Pharmaceutical Technicians 322 Nursing and Midwifery Associate Professionals 323 Traditional and Complementary Medicine Associate Professionals 324 Veterinary Technicians and Assistants 325 Other Health Associate Professionals
broader transitive: Technicians and associate professionals

Business and administration associate professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Business and administration associate professionals perform mostly technical tasks connected with the practical application of knowledge relating to financial accounting and transaction matters, mathematical calculations, human resource development, selling and buying financial instruments, specialized secretarial tasks, and enforcing or applying government rules. Also included are workers who provide business services such as customs clearance, conference planning, job placements, buying and selling real estate or bulk commodities, and serving as agents for performers such as athletes and artists. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include recording and transmitting buy and sell orders for securities, stocks, bonds or other financial instruments and for foreign exchange for future or immediate delivery; submitting credit and loan applications to management with recommendations for approval or rejection; approving or rejecting applications within authorized limits ensuring that credit standards of the institution are respected; maintaining complete records of all financial transactions of an undertaking according to general bookkeeping principles, with guidance from accountants; assisting in planning and performing mathematical, statistical, actuarial, accounting and related calculations; selling and buying financial instruments. Occupations in this sub-major group are classified into the following minor groups: 331 Financial and Mathematical Associate Professionals 332 Sales and Purchasing Agents and Brokers 333 Business Services Agents 334 Administrative and Specialized Secretaries 335 Government Regulatory Associate Professionals
broader transitive: Technicians and associate professionals

Legal, social, cultural and related associate professionals
type: NamedIndividual
type: Concept
type: Occupation
comment: Legal, social, cultural and related associate professionals perform technical tasks connected with the practical application of knowledge relating to legal services, social work, culture, food preparation, sport and religion. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing technical and practical services and support functions in legal processes and investigations, social and community assistance programmes, and religious and cultural activities; participating and adjudicating in sporting events; developing and delivering sports coaching, fitness and recreational programmes; combining creative and technical skills in a variety of artistic, cultural and culinary activities; creating dishes and menus and overseeing the preparation of meals. Occupations in this sub-major group are classified into the following minor groups: 341 Legal, Social and Religious Associate Professionals 342 Sports and Fitness Workers 343 Artistic, Cultural and Culinary Associate Professionals
broader transitive: Technicians and associate professionals

Information and communications technicians
type: NamedIndividual
type: Concept
type: Occupation
comment: Information and communications technicians provide support for the day-to-day running of computer systems, communications systems and networks, and perform technical tasks related to telecommunications, broadcast image and sound as well as other types of telecommunications signals on land, sea or in aircraft. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing assistance to information and communications systems users; installing new programs and equipment; establishing, operating and maintaining network and other data communications systems; installing, monitoring and supporting Internet and Intranet websites or web server hardware or software; modifying web pages; and performing web server backup and recovery operations; controlling equipment to record sound, edit and mix image and sound recordings; controlling and maintaining transmitting and broadcast systems and satellite systems for radio and television programmes; controlling and maintaining radio communications systems, satellite services and multiplex systems on land, sea or in aircraft; providing technical assistance connected with research and development of computer systems and telecommunications equipment, or testing prototypes; designing and preparing blueprints of circuitry according to the specifications given; providing technical supervision of the manufacture, utilization, maintenance and repair of telecommunications systems. Occupations in this sub-major group are classified into the following minor groups: 351 Information and Communications Technology Operations and User Support Technicians 352 Telecommunications and Broadcasting Technicians
broader transitive: Technicians and associate professionals

Clerical support workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Clerical support workers record, organize, store, compute and retrieve information, and perform a number of clerical duties in connection with money-handling operations, travel arrangements, requests for information, and appointments. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by clerical support workers usually include: stenography, typing, and operating word processors and other office machines; entering data into computers; carrying out secretarial duties; recording and computing numerical data; keeping records relating to stocks, production and transport; keeping records relating to passenger and freight transport; carrying out clerical duties in libraries; filing documents; carrying out duties in connection with mail services; preparing and checking material for printing; assisting persons who cannot read or write with correspondence; performing money-handling operations; dealing with travel arrangements; supplying information requested by clients and making appointments; operating a telephone switchboard. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 41 General and Keyboard Clerks 42 Customer Services Clerks 43 Numerical and Material Recording Clerks 44 Other Clerical Support Workers

General and keyboard clerks
type: NamedIndividual
type: Concept
type: Occupation
comment: General and keyboard clerks record, organize, store and retrieve information and perform a wide range of clerical and administrative tasks according to established procedures. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording, preparing, sorting, classifying and filing information; sorting, opening and sending mail; preparing reports and correspondence of a routine nature; photocopying and faxing documents; operating personal computers, word processors or typewriters to record, input and process text and data; proofreading and correcting copy; preparing invoices and checking figures. Occupations in this sub-major group are classified into the following minor groups: 411 General Office Clerks 412 Secretaries (general) 413 Keyboard Operators
broader transitive: Clerical support workers

Customer services clerks
type: NamedIndividual
type: Concept
type: Occupation
comment: Customer services clerks deal with clients in connection with money-handling operations, travel arrangements, requests for information, making appointments, operating telephone switchboards, and interviewing for surveys or to complete applications for eligibility for services. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: performing money-handling operations in banks, post offices, betting and gambling establishments, or dealing with travel arrangements; supplying information requested by clients and making appointments; operating telephone switchboards; greeting and receiving visitors; interviewing survey respondents; interviewing applicants for services. Occupations in this sub-major group are classified into the following minor groups: 421 Tellers, Money Collectors and Related Clerks 422 Client Information Workers
broader transitive: Clerical support workers

Numerical and material recording clerks
type: NamedIndividual
type: Concept
type: Occupation
comment: Numerical and material recording clerks obtain, compile and compute accounting, bookkeeping, statistical, financial and other numerical data, and take charge of cash transactions incidental to business matters. Some occupations classified here keep records of goods produced, purchased, stocked and dispatched, and of materials needed at specified production dates, or keep records of operational aspects and coordinate the timing of passenger and freight transport. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: helping with accounting and bookkeeping records and computations; calculating unit production costs; calculating wages and in some cases preparing wage packets and paying wages; taking charge of cash transactions incidental to the business; obtaining, compiling and computing statistical or actuarial data; performing clerical tasks relating to the financial transactions of an insurance establishment, bank or similar establishment; recording produced, stocked, ordered and dispatched goods; recording production materials received, put into stock or issued; computing quantities of the production materials required at specified dates and helping with preparation and checking of production operation schedules; keeping records of operational aspects and coordinating the timing of passenger and freight transport. Occupations in this sub-major group are classified into the following minor groups: 431 Numerical Clerks 432 Material Recording and Transport Clerks
broader transitive: Clerical support workers

Other clerical support workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Other clerical support workers sort and deliver mail, file documents, prepare information for processing, maintain personnel records, check material for consistency with original source material, assist persons who cannot read or write, and perform various other specialized clerical duties. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording information regarding acquisition, issue and return of library books; classifying and filing various documents and other records; maintaining personnel records; sorting, recording and delivering mail from post offices, as well as from or within an enterprise; coding; correcting proofs; performing a range of miscellaneous clerical duties; writing on behalf of persons who are unable to read or write. Occupations in this sub-major group are classified into the following minor group: 441 Other Clerical Support Workers
broader transitive: Clerical support workers

Service and sales workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Services and sales workers provide personal and protective services related to travel, housekeeping, catering, personal care, protection against fire and unlawful acts; or demonstrate and sell goods in wholesale or retail shops and similar establishments, as well as at stalls and on markets. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by services and sales workers usually include: organizing and providing services during travel; housekeeping; preparing and serving of food and beverages; caring for children; providing personal and basic health care at homes or in institutions, as well as hairdressing, beauty treatment and companionship; telling fortunes; embalming and arranging funerals; providing security services and protecting individuals and property against fire and unlawful acts; enforcing of law and order; posing as models for advertising, artistic creation and display of goods; selling goods in wholesale or retail establishments, as well as at stalls and on markets; and demonstrating goods to potential customers. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 51 Personal Services Workers 52 Sales Workers 53 Personal Care Workers 54 Protective Services Workers

Personal service workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Personal services workers provide personal services related to travel, housekeeping, catering and hospitality, hairdressing and beauty treatment, animal care grooming and training, companionship and other services of a personal nature. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: organizing and providing services in connection with travel and sightseeing; housekeeping; preparing and serving food and beverages; hairdressing and beauty treatment; telling fortunes; embalming and arranging funerals; grooming, caring for and training animals; teaching people to drive motor vehicles; providing companionship and other personal services. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 511 Travel Attendants, Conductors and Guides 512 Cooks 513 Waiters and Bartenders 514 Hairdressers, Beauticians and Related Workers 515 Building and Housekeeping Supervisors 516 Other Personal Services Workers
broader transitive: Service and sales workers

Sales workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Sales workers sell and demonstrate goods in wholesale or retail shops, at stalls and markets, door-to-door, via telephone or customer contact centres. They may record and accept payment for goods and services purchased, and may operate small retail outlets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: selling goods in wholesale or retail establishments, at street or market stalls, door-to-door, via telephone or customer contact centres; demonstrating and displaying goods to potential customers; selling and serving food for immediate consumption at counters and in the street; buying or contracting a regular supply of products to be sold; stacking and displaying goods for sale and wrapping or packing goods sold; determining product mix, stock and price levels for goods to be sold; operating cash registers, optical price scanners, computers or other equipment to record and accept payment for the purchase of goods and services. Supervision of other workers may be required in some occupations classified here. Occupations in this sub-major group are classified into the following minor groups: 521 Street and Market Salespersons 522 Shop Salespersons 523 Cashiers and Ticket Clerks 524 Other Sales Workers
broader transitive: Service and sales workers

Personal care workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Personal care workers provide care, supervision and assistance for children, patients and elderly, convalescent or disabled persons in institutional and residential settings. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assisting with mobility, washing and other personal needs; assisting children individually to learn social skills; supervising and participating in activities that enhance children’s physical, social, emotional and intellectual development; observing and reporting concerns to appropriate health or social service workers. Occupations in this sub-major group are classified into the following minor groups: 531 Child Care Workers and Teachers’ Aides 532 Personal Care Workers in Health Services
broader transitive: Service and sales workers

Protective services workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Protective services workers protect individuals and property against fire and other hazards, maintain law and order and enforce laws and regulations. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preventing, fighting and extinguishing fires; rescuing people from burning buildings and accident sites and those trapped in dangerous situations; maintaining law and order, enforcing laws and regulations, patrolling public areas and arresting suspected offenders; directing traffic and assuming authority in the event of accidents; watching over and maintaining order among inmates of prisons, reformatories or penitentiaries; patrolling or monitoring premises to guard property against theft and vandalism, controlling access to establishments and maintaining order and enforcing regulations at public events and within establishments. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 541 Protective Services Workers
broader transitive: Service and sales workers

Skilled agricultural, forestry and fishery workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Skilled agricultural, forestry and fishery workers grow and harvest field or tree and shrub crops; gather wild fruits and plants; breed, tend or hunt animals; produce a variety of animal husbandry products; cultivate, conserve and exploit forests; breed or catch fish; and cultivate or gather other forms of aquatic life in order to provide food, shelter and income for themselves and their households. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by skilled agricultural, forestry and fishery workers usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; gathering wild fruits and plants; breeding, raising, tending or hunting animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; cultivating, conserving and exploiting forests; breeding or catching fish; cultivating or gathering other forms of aquatic life; storing and carrying out some basic processing of their produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 61 Market-oriented Skilled Agricultural Workers 62 Market-oriented Skilled Forestry, Fishery and Hunting Workers 63 Subsistence Farmers, Fishers, Hunters and Gatherers

Market-oriented skilled agricultural workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Market-oriented skilled agricultural workers plan, organize and perform farming operations to grow and harvest field or tree and shrub crops; and to produce a variety of animals and animal products for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; raising, breeding and tending animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; storing and carrying out some processing of produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 611 Market Gardeners and Crop growers 612 Animal Producers 613 Mixed Crop and Animal Producers
broader transitive: Skilled agricultural, forestry and fishery workers

Market-oriented skilled forestry, fishery and hunting workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Market-oriented skilled forestry, fishery and hunting workers plan, organize and perform operations to cultivate, conserve and exploit natural and plantation forests; breed and raise fish; harvest and catch fish; and hunt and trap animals, for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: renting or investing in equipment and machinery and purchasing supplies; planning and undertaking forestry, aquaculture, fishery and hunting operations; maintaining buildings, tanks, machinery and other equipment; delivering or marketing products; supervising and training other workers. Occupations in this sub-major group are classified into the following minor groups: 621 Forestry and Related Workers 622 Fishery Workers, Hunters and Trappers
broader transitive: Skilled agricultural, forestry and fishery workers

Subsistence farmers, fishers, hunters and gatherers
type: NamedIndividual
type: Concept
type: Occupation
comment: Subsistence farmers, fishers, hunters and gatherers grow and harvest field or tree and shrub crops, vegetables and fruit; gather wild fruits, medicinal and other plants; tend or hunt animals; catch fish and gather various forms of aquatic life in order to provide food, shelter and, in some cases, a minimum of cash income for themselves and their households. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, tending and harvesting field crops; growing vegetables, fruit and other tree and shrub crops; gathering wild fruits, medicinal and other plants; breeding, tending and feeding animals and poultry mainly to obtain meat, eggs, milk, hair, skin or other products; hunting or trapping animals; catching fish and gathering other forms of aquatic life; fetching water and gathering firewood; storing produce for later use and carrying out some processing of produce; building and maintaining houses and other shelters; making tools, clothes and utensils for use by the household; selling or bartering some products at local markets. Occupations in this sub-major group are classified into the following minor groups: 631 Subsistence Crop Farmers 632 Subsistence Livestock Farmers 633 Subsistence Mixed Crop and Livestock Farmers 634 Subsistence Fishers, Hunters, Trappers and Gatherers
broader transitive: Skilled agricultural, forestry and fishery workers

Craft and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Craft and related trades workers apply specific technical and practical knowledge and skills to construct and maintain buildings; form metal; erect metal structures; set machine tools or make, fit, maintain and repair machinery, equipment or tools; carry out printing work; and produce or process foodstuffs, textiles, wooden, metal and other articles, including handicraft goods. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of all stages of the production process, the materials and tools used, and the nature and purpose of the final product. Tasks performed by craft and related trades workers usually include: constructing, maintaining and repairing buildings and other structures; casting, welding and shaping metal; installing and erecting heavy metal structures, tackle and related equipment; making machinery, tools, equipment and other metal articles; setting for operators, or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, engines, vehicles, electrical and electronic instruments and other equipment; making precision instruments, jewellery, household and other precious metal articles, pottery, glass and related products; producing handicrafts; executing printing work; producing and processing foodstuffs and various articles made of wood, textiles, leather and related materials. Supervision of other workers may be included. Self-employed craft and related trades workers, who operate their own businesses either independently or with assistance from a small number of others, may also perform a range of tasks associated with management of the business, account and record keeping and client service, although such…

Building and related trades workers, excluding electricians
type: NamedIndividual
type: Concept
type: Occupation
comment: Building and related trades workers construct, maintain and repair buildings; erect and repair foundations, walls and structures of brick, stone and similar materials; shape and finish stone for building and other purposes. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, the materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: constructing, maintaining and repairing buildings and other structures, using traditional and/or modern building techniques; constructing and repairing foundations, walls and structures of brick, stone and similar materials; breaking quarried stone into slabs or blocks; cutting, shaping and finishing stone for building, ornamental, monumental and other purposes; erecting reinforced concrete frameworks and structures as well as finishing and repairing cement surfaces; cutting, shaping, assembling and maintaining wooden structures and fittings; performing miscellaneous construction and building maintenance tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 711 Building Frame and Related Trades Workers 712 Building Finishers and Related Trades Workers 713 Painters, Building Structure Cleaners and Related Trades Workers
broader transitive: Craft and related trades workers

Metal, machinery and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Metal, machinery and related trades workers cast, weld, forge and, by other methods, form metal; erect, maintain and repair heavy metal structures; engage in machine-tool setting as well as in fitting, maintaining and repairing machinery including engines and vehicles; or they produce tools and various non-precious metal articles. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product Tasks performed by workers in this sub-major group usually include: making moulds and cores for casting metal; casting, welding and shaping metal; installing, erecting, maintaining and repairing heavy metal structures, tackle and related equipment; forging and forming steel and other non-precious metals to make and repair machinery, tools, equipment and other articles; setting for operators or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, including engines and vehicles. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 721 Sheet and Structural Metal Workers, Moulders and Welders, and Related Workers 722 Blacksmiths, Toolmakers and Related Trades Workers 723 Machinery Mechanics and Repairers
broader transitive: Craft and related trades workers

Handicraft and printing workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Handicraft and printing workers combine artistic and manual skills to design, produce, maintain and decorate precision instruments, musical instruments, jewellery and other precious metals, pottery, porcelain and glassware, items made of wood or textile, leather or related materials, and printed products such as books, newspapers and magazines. They apply traditional and/or recently developed techniques to carve, mould, assemble, weave and decorate various articles; to compose and set type prior to printing; to set up and operate printing presses; to bind and finish printed products; and to prepare stencils and operate screen printing equipment. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work may be carried out by hand or involve the use of hand tools and hand-held power tools, and in some cases the set-up and operation of machinery and machine tools. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: making and repairing nautical, meteorological, optical and other precision instruments and equipment; making and repairing musical instruments; making jewellery and precious metalware; making pottery, porcelain ware, ceramics and glassware; painting and decorating various articles; producing handicraft articles in wood or textile, leather and related materials; performing printing or book-binding tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 731 Handicraft Workers 732 Printing Trades Workers
broader transitive: Craft and related trades workers

Electrical and electronic trades workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Electrical and electronics trades workers install, fit and maintain electrical wiring systems and machinery and other electrical apparatus, electrical transmission and supply lines and cables, and electronic and telecommunications equipment and systems. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: installing, maintaining, fitting and adjusting electrical and electronic wiring systems, machinery and equipment; examining blueprints, wiring diagrams and specifications to determine sequences and methods of operation; inspecting and testing electrical and electronic systems, equipment, cables and machinery to identify hazards, defects and the need for adjustment or repair; installing, maintaining and repairing electrical and telecommunications transmission lines; joining electrical, telecommunications and data cables; maintaining, troubleshooting, fitting, adjusting, testing and repairing electronic equipment such as commercial and office machines, electronic instruments and control systems, computers, and telecommunications and data transmission equipment. Occupations in this sub-major group are classified into the following minor groups: 741 Electrical Equipment Installers and Repairers 742 Electronics and Telecommunications Installers and Repairers
broader transitive: Craft and related trades workers

Food processing, wood working, garment and other craft and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Food processing, woodworking, garment and other craft and related trades workers treat and process agricultural and fisheries raw materials into food and other products, and produce and repair goods made of wood, textiles, fur, leather or other materials. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: treating and processing meat, fish, grain, fruit, vegetables and related materials into food stuffs, and tobacco into tobacco products; tasting and grading food products and beverages; treating and processing natural fibres, skins and hides; making and repairing furniture and other goods made of wood; preparing hides, skins and pelts for further use; making and repairing textiles, garments, hats, shoes and related products. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 751 Food Processing and Related Trades Workers 752 Wood Treaters, Cabinet-makers and Related Trades Workers 753 Garment and Related Trades Workers 754 Other Craft and Related Workers
broader transitive: Craft and related trades workers

Plant and machine operators and assemblers
type: NamedIndividual
type: Concept
type: Occupation
comment: Plant and machine operators and assemblers operate and monitor industrial and agricultural machinery and equipment on the spot or by remote control; drive and operate trains, motor vehicles and mobile machinery and equipment; or assemble products from component parts according to strict specifications and procedures. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of industrial and agricultural machinery and equipment, as well as an ability to cope with machine-paced operations and to adapt to technological innovations. Tasks performed by plant and machine operators and assemblers usually include: operating and monitoring mining or other industrial machinery and equipment for processing metal, minerals, glass, ceramics, wood, paper or chemicals; operating and monitoring machinery and equipment used to produce articles made of metal, minerals, chemicals, rubber, plastics, wood, paper, textiles, fur or leather, and which process foodstuffs and related products; driving and operating trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; and assembling products from component parts according to strict specifications and procedures. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 81 Stationary Plant and Machine Operators 82 Assemblers 83 Drivers and Mobile Plant Operators

Stationary plant and machine operators
type: NamedIndividual
type: Concept
type: Occupation
comment: Stationary plant and machine operators monitor and operate stationary industrial plant, machinery and equipment, or for which mobility is not an integral part of operation. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of the industrial plant, machinery or equipment being operated and monitored. Ability to cope with machine-paced operations and to adapt to innovations in machinery and equipment are often required. Tasks performed by workers in this sub-major group usually include: setting up, operating and monitoring a variety of stationary plant and machinery; detecting malfunctions and taking corrective action; examining outputs for defects and conformity with specifications and adjusting machine settings accordingly; performing maintenance, repairs and cleaning; recording data and maintaining production records. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 811 Mining and Mineral Processing Plant Operators 812 Metal Processing and Finishing Plant Operators 813 Chemical and Photographic Products Plant and Machine Operators 814 Rubber, Plastic and Paper Products Machine Operators 815 Textile, Fur and Leather Products Machine Operators 816 Food and Related Products Machine Operators 817 Wood Processing and Papermaking Plant Operators 818 Other Stationary Plant and Machine Operators
broader transitive: Plant and machine operators and assemblers

Assemblers
type: NamedIndividual
type: Concept
type: Occupation
comment: Assemblers assemble prefabricated parts or components to form subassemblies, products and equipment, according to procedures strictly laid down. The products worked on may be moved from one worker to the next along assembly lines. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assembling components into various types of product and equipment, according to strictly laid down procedures; reviewing work orders, specifications, diagrams and drawings to determine materials needed and assembly instructions; recording production and operational data on specified forms; inspecting and testing completed components and assemblies, wiring installations and circuits; rejecting faulty assemblies and components. Occupations in this sub-major group are classified into the following minor group: 821 Assemblers
broader transitive: Plant and machine operators and assemblers

Drivers and mobile plant operators
type: NamedIndividual
type: Concept
type: Occupation
comment: Drivers and mobile plant operators drive and tend trains and motor vehicles, or drive, operate and monitor industrial and agricultural machinery and equipment, or execute deck duties on board ship and other water-borne craft. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: driving and tending trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; carrying out deck duties on board ship and other water-borne craft. Occupations in this sub-major group are classified into the following minor groups: 831 Locomotive Engine Drivers and Related Workers 832 Car, Van and Motorcycle Drivers 833 Heavy Truck and Bus Drivers 834 Mobile Plant Operators 835 Ships’ Deck Crews and Related Workers
broader transitive: Plant and machine operators and assemblers

Elementary occupations
type: NamedIndividual
type: Concept
type: Occupation
comment: Elementary occupations involve the performance of simple and routine tasks which may require the use of hand-held tools and considerable physical effort. Most occupations in this major group require skills at the first ISCO skill level. Tasks performed by workers in elementary occupations usually include: cleaning, restocking supplies and performing basic maintenance in apartments, houses, kitchens, hotels, offices and other buildings; washing cars and windows; helping in kitchens and performing simple tasks in food preparation; delivering messages or goods; carrying luggage and handling baggage and freight; stocking vending-machines or reading and emptying meters; collecting and sorting refuse; sweeping streets and similar places; performing various simple farming, fishing, hunting or trapping tasks; performing simple tasks connected with mining, construction and manufacturing including product-sorting; packing and unpacking produce by hand, and filling shelves; providing various street services; pedalling or hand-guiding vehicles to transport passengers and goods; driving animal-drawn vehicles or machinery. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 91 Cleaners and Helpers 92 Agricultural, Forestry and Fishery Labourers 93 Labourers in Mining, Construction, Manufacturing and Transport 94 Food Preparation Assistants 95 Street and Related Sales and Services Workers 96 Refuse Workers and Other Elementary Workers

Cleaners and helpers
type: NamedIndividual
type: Concept
type: Occupation
comment: Cleaners and helpers perform various tasks in private households, hotels, offices, hospitals and other establishments, as well as in aircraft, trains, coaches, trams and similar vehicles, in order to keep the interiors and fixtures clean, and launder and press garments and textiles by hand. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: sweeping or vacuum cleaning; washing and polishing floors, furniture and other objects; taking care of linen and bedmaking; helping with preparation of meals and cleaning in kitchens; washing and cleaning cars and windows; pressing or laundering garments and textiles by hand. Occupations in this sub-major group are classified into the following minor groups: 911 Domestic, Hotel and Office Cleaners and Helpers 912 Vehicle, Window, Laundry and Other Hand Cleaning Workers
broader transitive: Elementary occupations

Agricultural, forestry and fishery labourers
type: NamedIndividual
type: Concept
type: Occupation
comment: Agricultural, forestry and fishery labourers perform simple and routine tasks in the production of crops and livestock, cultivation and maintenance of gardens and parks, exploitation and conservation of forests, and conduct of aquaculture and fisheries operations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: digging, raking and shovelling using hand tools; loading, unloading and stacking supplies, produce and other materials; watering, thinning, weeding and tending crops by hand or using hand tools; planting, harvesting, picking and collecting produce by hand; feeding, watering and cleaning animals and keeping their quarters clean; monitoring livestock and reporting on their condition; preparing and operating nets, lines and other fishing tackle and deck equipment; grading, sorting, bunching and packing produce into containers; performing minor repairs on fixtures, buildings, equipment, vessels and fences. Occupations in this sub-major group are classified into the following minor group: 921 Agricultural, Forestry and Fishery Labourers
broader transitive: Elementary occupations

Labourers in mining, construction, manufacturing and transport
type: NamedIndividual
type: Concept
type: Occupation
comment: Labourers in mining, construction, manufacturing and transport perform simple and routine manual tasks in mining, quarrying, civil engineering, building, manufacturing, transport and storage operations, and operate human-powered and animal-drawn vehicles and machinery. Most occupations in this sub-major group require skills at the first ISCO skill level. Task performed by workers in this sub-major group usually include: digging holes and spreading excavated materials, sand, soil and gravel using hand-held tools; sorting, loading, unloading, moving, stacking and storing materials, equipment, products, supplies, baggage and cargo by hand; cleaning machinery, equipment, tools and work sites; packing and unpacking material and products and filling containers and shelves with products by hand; operating human-powered and animal-drawn vehicles and machinery. Occupations in this sub-major group are classified into the following minor groups: 931 Mining and Construction Labourers 932 Manufacturing Labourers 933 Transport and Storage Labourers
broader transitive: Elementary occupations

Food preparation assistants
type: NamedIndividual
type: Concept
type: Occupation
comment: Food preparation assistants prepare and cook to order a small variety of pre-cooked food or beverages, clear tables, clean kitchen areas and wash dishes. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing simple or pre-prepared foods and beverages such as sandwiches, pizzas, fish and chips, salads and coffee; washing, cutting, measuring and mixing foods for cooking; operating cooking equipment such as grills, microwaves and deep-fat fryers; cleaning kitchens, food preparation areas and service areas; cleaning cooking and general utensils used in kitchens and restaurants. Occupations in this sub-major group are classified into the following minor group: 941 Food Preparation Assistants
broader transitive: Elementary occupations

Street and related sales and service workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Street and related sales and services workers sell goods (excluding food) for immediate consumption, and provide a variety of services on streets and in other public places such as stations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: buying or making various items for sale; loading and unloading items for sale and transporting them; obtaining the materials necessary to perform services; approaching people on the street to offer goods or services; cleaning and polishing shoes; cleaning and polishing car windows; running errands; assisting car drivers to find a parking place and ensuring that the car is not damaged during the driver’s absence; handing out leaflets and free newspapers; receiving immediate payment. Occupations in this sub-major group are classified into the following minor groups: 951 Street and Related Services Workers 952 Street Vendors (excluding Food)
broader transitive: Elementary occupations

Refuse workers and other elementary workers
type: NamedIndividual
type: Concept
type: Occupation
comment: Refuse workers and other elementary workers collect, process and recycle garbage from buildings, yards, streets and other public places. They keep streets and other public places clean and tidy, deliver and carry messages and packages and perform odd jobs for private households or establishments. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, loading and unloading garbage; sweeping streets, parks and other public places; chopping firewood; collecting and carrying firewood, water, packages, luggage and messages; beating dust out of carpets and performing other odd-job tasks. Occupations in this sub-major group are classified into the following minor groups: 961 Refuse Workers 962 Other Elementary Workers
broader transitive: Elementary occupations

Alimentary Tract and Metabolism
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653992

Stomatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653755
broader transitive: Alimentary Tract and Metabolism

Drugs for Acid Related Disorders
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653499
broader transitive: Alimentary Tract and Metabolism

Malgradate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0065512
broader transitive: Drugs for Acid Related Disorders

Omeprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0028978
broader transitive: Drugs for Acid Related Disorders

Pantoprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0081876
broader transitive: Drugs for Acid Related Disorders

Esomeprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0937846
broader transitive: Drugs for Acid Related Disorders

Proglumide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033321
broader transitive: Drugs for Acid Related Disorders

Drugs for Functional Gastrointestinal Disorders
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653766
broader transitive: Alimentary Tract and Metabolism

Domperidone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013015
broader transitive: Drugs for Functional Gastrointestinal Disorders

Antiemetics and Antinauseants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653765
broader transitive: Alimentary Tract and Metabolism

Bile and Liver Therapy Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654041
broader transitive: Alimentary Tract and Metabolism

Bile Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654040
broader transitive: Bile and Liver Therapy Drugs

Ursodeoxycholic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042105
broader transitive: Bile Therapy

Liver Therapy, Lipotropics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653559
broader transitive: Bile and Liver Therapy Drugs

Drugs for Bile Therapy and Lipotropics in Combination
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653658
broader transitive: Bile and Liver Therapy Drugs

Drugs for Constipation
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653756
broader transitive: Alimentary Tract and Metabolism

Lactulose
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022957
broader transitive: Drugs for Constipation

Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653721
broader transitive: Alimentary Tract and Metabolism

Sulfasalazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036078

Mesalazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0127615
broader transitive: Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents

Antiobesity Preparations, excl. Diet Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653760
broader transitive: Alimentary Tract and Metabolism

Digestives, incl. Enzymes
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653759
broader transitive: Alimentary Tract and Metabolism

Drugs Used in Diabetes
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653344
broader transitive: Alimentary Tract and Metabolism

Insulins and Analogues
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653579
broader transitive: Drugs Used in Diabetes

Insulin Lispro
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0293359
broader transitive: Insulins and Analogues

Insulin Glargine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0907402
broader transitive: Insulins and Analogues

Metformin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025598
broader transitive: Drugs Used in Diabetes

Gliclazide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017631
broader transitive: Drugs Used in Diabetes

Glimepiride
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0061323
broader transitive: Drugs Used in Diabetes

Sitagliptin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1565750
broader transitive: Drugs Used in Diabetes

Semaglutide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3885068
broader transitive: Drugs Used in Diabetes

Repaglinide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0246689
broader transitive: Drugs Used in Diabetes

Vitamins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042890
broader transitive: Alimentary Tract and Metabolism

Colecalciferol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008318
broader transitive: Vitamins

Calcifediol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006657
broader transitive: Vitamins

Biotin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005575
broader transitive: Vitamins

Mineral Supplements
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0556112
broader transitive: Alimentary Tract and Metabolism

Calcium, Combinations with Vitamin D and/or Other Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653309
broader transitive: Mineral Supplements

Tonics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3543842
broader transitive: Alimentary Tract and Metabolism

Anabolic Agents for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653709
broader transitive: Alimentary Tract and Metabolism

Appetite Stimulants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376447
broader transitive: Alimentary Tract and Metabolism

Other Alimentary Tract and Metabolism
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3542964
broader transitive: Alimentary Tract and Metabolism

Ademetionine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036002
broader transitive: Other Alimentary Tract and Metabolism

Blood and Blood Forming Organs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654015

Antithrombotic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1704311
broader transitive: Blood and Blood Forming Organs

Warfarin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0043031
broader transitive: Antithrombotic Agents

Clopidogrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0070166
broader transitive: Antithrombotic Agents

Ticlopidine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040207
broader transitive: Antithrombotic Agents

Prasugrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1620287
broader transitive: Antithrombotic Agents

Dabigatran Etexilate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1571583
broader transitive: Antithrombotic Agents

Rivaroxaban
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1739768
broader transitive: Antithrombotic Agents

Apixaban
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1831808
broader transitive: Antithrombotic Agents

Antihemorrhagics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085824
broader transitive: Blood and Blood Forming Organs

Antianemic Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653788
broader transitive: Blood and Blood Forming Organs

Cyanocobalamin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042845
broader transitive: Antianemic Preparations

Blood Substitutes and Perfusion Solutions
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653601
broader transitive: Blood and Blood Forming Organs

Other Hematological Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540010
broader transitive: Blood and Blood Forming Organs

Cardiovascular System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540036

Cardiac Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654025

Amiodarone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002598
broader transitive: Cardiac Therapy

Antihypertensives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003364
broader transitive: Cardiovascular System

Ambrisentan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1176329
broader transitive: Antihypertensives

Diuretics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012798
broader transitive: Cardiovascular System

Hydrochlorothiazide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020261
broader transitive: Diuretics

Furosemide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016860
broader transitive: Diuretics

Peripheral Vasodilators
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0724804
broader transitive: Cardiovascular System

Nicergoline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0028008
broader transitive: Peripheral Vasodilators

Vasoprotectives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0304533
broader transitive: Cardiovascular System

Beta Blocking Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001645
broader transitive: Cardiovascular System

Propanolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033497
broader transitive: Beta Blocking Agents

Atenolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004147
broader transitive: Beta Blocking Agents

Bisoprolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0053799
broader transitive: Beta Blocking Agents

Nebivolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0068475
broader transitive: Beta Blocking Agents

Atenolol and Other Diuretics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653013
broader transitive: Beta Blocking Agents

Calcium Channel Blockers
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System

Amlodipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0051696
broader transitive: Calcium Channel Blockers

Barnidipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078703
broader transitive: Calcium Channel Blockers

Lercanidipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0526399
broader transitive: Calcium Channel Blockers

Verapamil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042523
broader transitive: Calcium Channel Blockers

Agents Acting on the Renin-Angiotensin System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653735
broader transitive: Cardiovascular System

ACE Inhibitors, Plain
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653768
broader transitive: Agents Acting on the Renin-Angiotensin System

Enalapril
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014025
broader transitive: ACE Inhibitors, Plain

Ramipril
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0072973
broader transitive: ACE Inhibitors, Plain

Perindopril and Amlodipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2931929
broader transitive: ACE Inhibitors, Plain

Losartan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0126174
broader transitive: ACE Inhibitors, Plain

Valsartan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0216784
broader transitive: Agents Acting on the Renin-Angiotensin System

Telmisartan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0248719
broader transitive: ACE Inhibitors, Plain

Olmesartan Medoxomil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0386393
broader transitive: ACE Inhibitors, Plain

Candesartan and Diuretics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653044
broader transitive: Agents Acting on the Renin-Angiotensin System

Olmesartan Medoxomil and Amlodipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652731
broader transitive: Agents Acting on the Renin-Angiotensin System

Lipid Modifying Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653535
broader transitive: Cardiovascular System

HMG CoA Reductase Inhibitors
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3539119
broader transitive: Lipid Modifying Agents

Simvastatin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074554
broader transitive: HMG CoA Reductase Inhibitors

Atrovastatin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0286651
broader transitive: HMG CoA Reductase Inhibitors

Rosuvastatin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0965129
broader transitive: Lipid Modifying Agents

Ezetimibe
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1142985
broader transitive: Lipid Modifying Agents

Dermatologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011625

Antifungals for Dermatological Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653281
broader transitive: Dermatologicals

Emollients and Protectives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653752
broader transitive: Dermatologicals

Preparations for Treatment of Wounds and Ulcers
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653566
broader transitive: Dermatologicals

Antipruritics, incl. Antihistamines, Anesthetics, etc.
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653761
broader transitive: Dermatologicals

Antipsoriatics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1874314
broader transitive: Dermatologicals

Antibiotics and Chemotherapeutics for Dermatological Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653726
broader transitive: Dermatologicals

Corticosteroids, Dermatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals

Hydrocortisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020268
broader transitive: Corticosteroids, Dermatological Preparations

Antispetic and Disinfectants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653284
broader transitive: Dermatologicals

Medicated Dressings
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0471863
broader transitive: Dermatologicals

Anti-Acne Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358061
broader transitive: Dermatologicals

Other Dermatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653942
broader transitive: Dermatologicals

Genito Urinary System and Sex Hormones
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653431

Gynecological Antiinfectives and Antiseptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653587
broader transitive: Genito Urinary System and Sex Hormones

Other Gynecologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653939
broader transitive: Genito Urinary System and Sex Hormones

Sex Hormones and Modulators of the Genital System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653561
broader transitive: Genito Urinary System and Sex Hormones

Desogestrel and Ethinylestradiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1112096
broader transitive: Sex Hormones and Modulators of the Genital System

Drospirenone and Ethinylestradiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2604206
broader transitive: Sex Hormones and Modulators of the Genital System

Progestogens and Estrogens Systemic Contraceptives, Sequential Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540748
broader transitive: Sex Hormones and Modulators of the Genital System

Dienogest and Estradiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2936902
broader transitive: Sex Hormones and Modulators of the Genital System

Etonogestrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0047683
broader transitive: Sex Hormones and Modulators of the Genital System

Desogestrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0057558
broader transitive: Sex Hormones and Modulators of the Genital System

Tibolone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0076660
broader transitive: Sex Hormones and Modulators of the Genital System

Urologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653764
broader transitive: Genito Urinary System and Sex Hormones

Oxybutynin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0069805
broader transitive: Urologicals

Tolterodine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0388753
broader transitive: Urologicals

Trospium
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0772089
broader transitive: Urologicals

Sildenafil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0529793
broader transitive: Urologicals

Tadalafil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1176316
broader transitive: Urologicals

Alfuzosin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0051150
broader transitive: Urologicals

Tamsulosin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0257343
broader transitive: Urologicals

Dustasteride
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0754659
broader transitive: Urologicals

Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653821

Pituitary and Hypothalamic Hormones and Analogues
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653567
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins

Corticotropin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001655
broader transitive: Pituitary and Hypothalamic Hormones and Analogues

Tetracosactide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010192
broader transitive: Pituitary and Hypothalamic Hormones and Analogues

Corticosteroids for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653708
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins

Glucocorticoids, Systemic
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540777
broader transitive: Corticosteroids for Systemic Use

Betamethasone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005308
broader transitive: Glucocorticoids, Systemic

Dexamethasone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011777
broader transitive: Glucocorticoids, Systemic

Methylprednisolone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025815
broader transitive: Glucocorticoids, Systemic

Prednisolone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032950
broader transitive: Glucocorticoids, Systemic

Prednisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032952
broader transitive: Glucocorticoids, Systemic

Hydrocortisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020268
broader transitive: Glucocorticoids, Systemic

Deflazacort
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0057258
broader transitive: Glucocorticoids, Systemic

Thyroid Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540775
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins

Levothyroxine Sodium
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0079691
broader transitive: Thyroid Therapy

Thiamazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025644
broader transitive: Thyroid Therapy

Pancreatic Hormones
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030292
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins

Calcium Homeostasis
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653518
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins

Antiinfectives for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653775

Antibacterials for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653727
broader transitive: Antiinfectives for Systemic Use

Amoxicillin and Beta-Lactamase Inhibitor
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653015
broader transitive: Antibacterials for Systemic Use

Ceftriaxone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007561
broader transitive: Antibacterials for Systemic Use

Antimycotics for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653762
broader transitive: Antiinfectives for Systemic Use

Antimycobacterials
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0360390
broader transitive: Antiinfectives for Systemic Use

Rifampicin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035608
broader transitive: Antimycobacterials

Antivirals for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653777
broader transitive: Antiinfectives for Systemic Use

Aciclovir
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001367
broader transitive: Antivirals for Systemic Use

Valaciclovir
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0249458
broader transitive: Antivirals for Systemic Use

Immune Sera and Immunoglobulins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653581
broader transitive: Antiinfectives for Systemic Use

Immunoglobulins, Normal Human, for Intravascular Adm.
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652960
broader transitive: Immune Sera and Immunoglobulins

Tetanus Immunoglobulin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4048265
broader transitive: Immune Sera and Immunoglobulins

Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042210
broader transitive: Antiinfectives for Systemic Use

Diphtheria Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012551
broader transitive: Vaccines

Hepatitis B, Purified Antigen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652493
broader transitive: Vaccines

Poliomyelitis, Trivalent, Inactivated, Whole Virus
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652521
broader transitive: Vaccines

Other Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653947
broader transitive: Vaccines

Antineoplastic and Immunomodulating Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653621

Antineoplastic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003392
broader transitive: Antineoplastic and Immunomodulating Agents

Cyclophosphamide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010583
broader transitive: Antineoplastic Agents

Methotrexate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025677
broader transitive: Antineoplastic Agents

Cladribine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0092801
broader transitive: Antineoplastic Agents

Mitoxantrone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026259
broader transitive: Antineoplastic Agents

Alectinib
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3853921
broader transitive: Antineoplastic Agents

Ofatumumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1832027
broader transitive: Antineoplastic Agents

Rituximab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0393022
broader transitive: Antineoplastic Agents

Trastuzumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0728747
broader transitive: Antineoplastic Agents

Endocrine Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540795
broader transitive: Antineoplastic and Immunomodulating Agents

Tamoxifen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039286
broader transitive: Endocrine Therapy

Immunostimulants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001551
broader transitive: Antineoplastic and Immunomodulating Agents

Interferon Beta Natural
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015980
broader transitive: Immunostimulants

Interferon Beta-1a
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0254119
broader transitive: Immunostimulants

Interferon Beta-1b
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0244713
broader transitive: Immunostimulants

Peginterferon Alfa-2b
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0796545
broader transitive: Immunostimulants

Peginterferon Beta-1a
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3848580
broader transitive: Immunostimulants

BCG Vaccine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004886
broader transitive: Immunostimulants

Glatiramer Acetate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0289884
broader transitive: Immunostimulants

Immunosuppressants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021081
broader transitive: Antineoplastic and Immunomodulating Agents

Natalizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1172734
broader transitive: Immunosuppressants

Fingolimod
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1699926
broader transitive: Immunosuppressants

Teriflunomide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1718383
broader transitive: Immunosuppressants

Alemtuzumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0383429
broader transitive: Immunosuppressants

Ocrelizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1882138
broader transitive: Immunosuppressants

Ozanimod
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4278675
broader transitive: Immunosuppressants

Cladribine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0092801
broader transitive: Immunosuppressants

Siponimod
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3657824
broader transitive: Immunosuppressants

Daclizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0663182
broader transitive: Immunosuppressants

Ustekinumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1608841
broader transitive: Immunosuppressants

Tocilizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1609165
broader transitive: Immunosuppressants

Secukinumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3179547
broader transitive: Immunosuppressants

Azathioprine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004482
broader transitive: Immunosuppressants

Methotrexate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025677
broader transitive: Immunosuppressants

Dimethyl Fumarate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0058218
broader transitive: Immunosuppressants

Musculo-Skeletal System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653821

Antiinflammatory and Antirheumatic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653623
broader transitive: Musculo-Skeletal System

Antiinflammatory and Antirheumatic Products, Non-Steroids
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653622
broader transitive: Antiinflammatory and Antirheumatic Products

Indometacin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021246
broader transitive: Antiinflammatory and Antirheumatic Products

Ketorolac
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0073631
broader transitive: Antiinflammatory and Antirheumatic Products

Ibuprofen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020740
broader transitive: Antiinflammatory and Antirheumatic Products

Etoricoxib
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0972314
broader transitive: Antiinflammatory and Antirheumatic Products

Topical Products for Joint and Muscular Pain
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653753
broader transitive: Musculo-Skeletal System

Muscle Relaxants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358430
broader transitive: Musculo-Skeletal System

Botulinum Toxin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006055
broader transitive: Muscle Relaxants

Baclofen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004609
broader transitive: Muscle Relaxants

Tizanidine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0146011
broader transitive: Muscle Relaxants

Dantrolene
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010976
broader transitive: Muscle Relaxants

Antigout Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018100
broader transitive: Musculo-Skeletal System

Drugs for Treatment of Bone Diseases
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653497
broader transitive: Musculo-Skeletal System

Denosumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1690432
broader transitive: Drugs for Treatment of Bone Diseases

Other Drugs for Disorders of the Musculo-Skeletal System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653872
broader transitive: Musculo-Skeletal System

Nervous System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3542961

Anesthetics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002932
broader transitive: Nervous System

Analgesics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002771
broader transitive: Nervous System

Codeine, Combinations excl. Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653191
broader transitive: Analgesics

Acetylsalicylic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004057
broader transitive: Analgesics

Acetylsalicylic Acid, Combinations excl. Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653192
broader transitive: Analgesics

Paracetamol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000970
broader transitive: Analgesics

Cannabinoids
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006864
broader transitive: Analgesics

Sumatriptan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0075632
broader transitive: Analgesics

Zolmitriptan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0528166
broader transitive: Analgesics

Antiepileptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003299
broader transitive: Nervous System

Phenobarbital
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031412
broader transitive: Antiepileptics

Barbexaclone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0105205
broader transitive: Antiepileptics

Phenytoin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031507
broader transitive: Antiepileptics

Clonazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009011
broader transitive: Antiepileptics

Carbamazepine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006949
broader transitive: Antiepileptics

Oxcarbazepine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0069751
broader transitive: Antiepileptics

Valproic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042291
broader transitive: Antiepileptics

Vigabatrin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0048044
broader transitive: Antiepileptics

Lamotrigine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0064636
broader transitive: Antiepileptics

Topiramate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0076829
broader transitive: Antiepileptics

Gabapentin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0060926
broader transitive: Antiepileptics

Levetiracetam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0377265
broader transitive: Antiepileptics

Pregabalin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0657912
broader transitive: Antiepileptics

Cannabidiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006863
broader transitive: Antiepileptics

Anti-Parkinson Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003405
broader transitive: Nervous System

Levodopa and Decarboxylase Inhibitor
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653004
broader transitive: Anti-Parkinson Drugs

Amantadine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002403
broader transitive: Anti-Parkinson Drugs

Ropinirole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0244821
broader transitive: Anti-Parkinson Drugs

Pramipexole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074710
broader transitive: Anti-Parkinson Drugs

Cabergoline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0107994
broader transitive: Anti-Parkinson Drugs

Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653516
broader transitive: Nervous System

Zuclopenthixol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376160
broader transitive: Psycholeptics

Olanzapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0171023
broader transitive: Psycholeptics

Quetiapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0123091
broader transitive: Psycholeptics

Aripiprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0299792
broader transitive: Psycholeptics

Paliperidone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0753678
broader transitive: Psycholeptics

Anxiolytics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040616
broader transitive: Psycholeptics

Diazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012010
broader transitive: Psycholeptics

Lorazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024002
broader transitive: Psycholeptics

Bromazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006213
broader transitive: Psycholeptics

Clobazam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0055891
broader transitive: Psycholeptics

Prazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032910
broader transitive: Psycholeptics

Alprazolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002333
broader transitive: Psycholeptics

Etizolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0059862
broader transitive: Psycholeptics

Hypnotics and Sedatives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020592
broader transitive: Psycholeptics

Flurazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016375
broader transitive: Hypnotics and Sedatives

Triazolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040879
broader transitive: Hypnotics and Sedatives

Brotizolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0054151
broader transitive: Hypnotics and Sedatives

Zolpidem
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078839
broader transitive: Hypnotics and Sedatives

Melatonin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025219
broader transitive: Hypnotics and Sedatives

Psychoanaleptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653540
broader transitive: Nervous System

Antidepressants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003289
broader transitive: Psychoanaleptics

Amitriptyline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002600
broader transitive: Antidepressants

Fluoxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016365
broader transitive: Antidepressants

Citalopram
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008845
broader transitive: Antidepressants

Paroxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0070122
broader transitive: Antidepressants

Sertraline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074393
broader transitive: Antidepressants

Escitalopram
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1099456
broader transitive: Antidepressants

Trazodone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040805
broader transitive: Antidepressants

Mitrazapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0049506
broader transitive: Antidepressants

Venlafaxine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078569
broader transitive: Antidepressants

Reboxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0168388
broader transitive: Antidepressants

Duloxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0245561
broader transitive: Antidepressants

Desvenlafaxine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1880288
broader transitive: Psychoanaleptics

Vertioxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3661282
broader transitive: Antidepressants

Modafinil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0066677
broader transitive: Psychoanaleptics

Acetylcarnitine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001040
broader transitive: Psychoanaleptics

Amitriptyline and Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653016
broader transitive: Psychoanaleptics

Rivastigmine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0649350
broader transitive: Psychoanaleptics

Other Nervous System Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653848
broader transitive: Nervous System

Naltrexone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027360
broader transitive: Other Nervous System Drugs

Betahistine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005301
broader transitive: Other Nervous System Drugs

Cinnarizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008803
broader transitive: Other Nervous System Drugs

Flunarizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016295
broader transitive: Other Nervous System Drugs

Cinnarizine, Combinations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653100
broader transitive: Other Nervous System Drugs

Riluzole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0073379
broader transitive: Other Nervous System Drugs

Fampridine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000477
broader transitive: Other Nervous System Drugs

Antiparastic Products, Insecticides and Repllents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653620

Antiprotozoals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003416
broader transitive: Antiparastic Products, Insecticides and Repllents

Hydroxychloroquine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020336
broader transitive: Antiprotozoals

Anthelmintics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003158
broader transitive: Antiparastic Products, Insecticides and Repllents

Ectoparasiticides, incl. Scabicides, Insecticides and Repellents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653591
broader transitive: Antiparastic Products, Insecticides and Repllents

Respiratory System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0282686

Nasal Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653410
broader transitive: Respiratory System

Throat Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653754
broader transitive: Respiratory System

Drugs for Obstructive Airway Diseases
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653498
broader transitive: Respiratory System

Terbutaline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039542
broader transitive: Drugs for Obstructive Airway Diseases

Formoterol and Budesonide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1276807
broader transitive: Drugs for Obstructive Airway Diseases

Fluticasone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0082607
broader transitive: Drugs for Obstructive Airway Diseases

Tiotropium Bromide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1306772
broader transitive: Drugs for Obstructive Airway Diseases

Salbutamol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001927
broader transitive: Drugs for Obstructive Airway Diseases

Montelukast
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0298130
broader transitive: Drugs for Obstructive Airway Diseases

Cough and Cold Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1511537
broader transitive: Respiratory System

Antihistamines for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653763
broader transitive: Respiratory System

Chlorphenamine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008281
broader transitive: Antihistamines for Systemic Use

Thiethylperazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039865
broader transitive: Antihistamines for Systemic Use

Cetirizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0055147
broader transitive: Antihistamines for Systemic Use

Levocetirizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1174893
broader transitive: Antihistamines for Systemic Use

Other Respiratory System Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653833
broader transitive: Respiratory System

Sensory Organs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654000

Ophthalmologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2013096
broader transitive: Sensory Organs

Tafluprost
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1451502
broader transitive: Ophthalmologicals

Otologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653485
broader transitive: Sensory Organs

Ophthalmologicals and Otologicals Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653568
broader transitive: Sensory Organs

Various
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540763

Allergens
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002092
broader transitive: Various

All Other Therapeutic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653767
broader transitive: Various

Calcium Folinate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0731033
broader transitive: All Other Therapeutic Products

Diagnostic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various

General Nutrients
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653491
broader transitive: Various

All Other Non-Therapeutic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653748
broader transitive: Various

Contrast Media
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009924
broader transitive: Various

Diagnostic Radiopharmaceuticals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0360048
broader transitive: Various

Therapeutic Radiopharmaceuticals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358509
broader transitive: Various

Surgical Dressings
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653515
broader transitive: Various

Operative Procedure on Upper Extremity
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0186318
comment: Surgical procedure involving an upper extremity.

Surgical Procedure on Lower Extremity
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0187763
comment: Surgical procedure involiving a lower extremity.

Cone Biopsy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0195324
comment: The excision of a cone of tissue, especially of the CERVIX UTERI. [Definition Source: MSH]

Partial Cystectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
comment: The surgical removal of part of bladder.

Amenorrhea due to Pituitary Dysfunction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5546135
comment: The absence of menses in a woman who has achieved reproductive age due to disorder of pituitary gland. [Partial Defintion Source: NCI
broader transitive: Amenorrhea

Excision of Benign Neoplasm
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1293110
comment: Surgical removal of bening neoplasm.
broader transitive: Excision of Neoplasm

Thyroid Gland Excision
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040145
comment: Surgery to remover part or all of the thyroid gland. [Definition Source: NCI]

Caucasian
type: NamedIndividual
type: Concept
type: Group (social concept)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0043157
comment: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. (OMB) [Definition Source: NCI]

Abdominoplasty
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0198542
comment: Surgical removal of excess abdominal skin and fat and tightening of the ABDOMINAL WALL. Abdominoplasty may include LIPECTOMY of INTRA-ABDOMINAL FAT, tightening of the ABDOMINAL MUSCLES, and re-creation of the UMBILICUS. [Definition Source: MSH]

Black African
type: NamedIndividual
type: Concept
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337824
comment: Denotes a person with ancestral origins are in any of the countries of Africa. [Definition Source: NCI]

Autoimmune Pancytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0271893
comment: The autoimmune inability of the bone marrow to produce hematopoietic elements. [Definition Source: NCI]
broader transitive: Pancytopenia

Bell's Palsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376175
comment: A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376) [Defintion Source: MSH]
broader transitive: Cranial Nerve VII Palsy

Prolapsed Lumbar Intervertebral Disc
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0281899
comment: Lumbar Hernia [Definition Source: MedDRA]
broader transitive: Hernia

Rhinoseptoplasty
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0189054
comment: Rhinoseptoplasty, also known as rhino septoplasty or septorhinoplasty, is a nose job procedure that makes cosmetic changes while realigning a malformed nasal septum. [Defintion Source: themodernplasticsurgery]

Operation on Abdominal Region
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0198482
comment: A surgical procedure located in the abdomnial region.

Sciatica
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036396
comment: Pain in the lower back and hip radiating in the distribution of the sciatic nerve. [HPO:probinson, PMID:17872935] (HPO)
broader transitive: Disease or Disorder

Coronary Artery Bypass Graft
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010055
comment: Surgery performed to bypass partially or completely occluded coronary arteries, thereby increasing the blood supply of the heart. [Definition Source: NCI]

Lumbar Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0401119
comment: Lumbar Hernia [Definition Source: SNOMEDCT]
broader transitive: Hernia

Pulmonary Thromboembolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0524702
comment: Pulmonary embolism is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. [PMID:29770793]
broader transitive: Thromboembolism

Percutaneous Endoscopic Gastrostomy (PEG)
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
comment: The placement of a feeding tube through the abdominal wall into the stomach using an endoscope. [Definition Source: NCI]

Drainage of Bartholin's Abscess
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0403848
comment: Drainage of abscess of Barholin's gland.

Hysterectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020699
comment: A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). [Definition source: NCI]

Atopic Dermatitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011615
comment: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. [Definition Source: MSH]
broader transitive: Eczema

Cardioversion
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
comment: The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one, by pharmacologic means using medications or by electrical cardioversion using a defibrillator. [Definition Source: NCI]

Replacement of Aortic Valve
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003506

Removal of Acoustic Neuroma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0576748
comment: Surgical removal of acoustic neuroma.

Excision of Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0576763
comment: Surgical removal of basal cell carcinoma.

Hypertriglyceridaemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020557
comment: A condition of elevated levels of TRIGLYCERIDES in the blood. [Definition Source: MSH]
broader transitive: Disease or Disorder

Neutropenic Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027947
comment: A decrease in the number of NEUTROPHILS found in the blood. [Definition Source: MSH]
broader transitive: Finding

Head and Neck Approaches
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
comment: Any approach involiving the head and neck region.

Black (ethnic group)
type: NamedIndividual
type: Concept
type: Group (social concept)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005680
comment: A person having origins in the original peoples of sub-Saharan Africa or the Caribbean.

Asian (ethnic group)
type: NamedIndividual
type: Concept
type: Group (social concept)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1282531
comment: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (OMB) [Definition Source: NCI]

Repair of Knee Cruciate Ligaments
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0188184

Excision of Neoplasm
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1299802
comment: The surgical removal of a neoplasm.

Motor Neuron Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085084
comment: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) [Definition Source: MSH]
broader transitive: Central Nervous System Degenerative Disorder

Cholecystectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008320
comment: Surgical removal of the gallbladder. [Definition Source: NCI]

Surgical Procedure on Thorax
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0524832
comment: Any surgery performed inside the thoracic cavity. [Definition Source: NCI]

Laminectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022983
comment: A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots. [Defintion Source: MSH]

Allergic Asthma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155877
comment: Allergic Asthma
broader transitive: Asthma

Hispanic
type: NamedIndividual
type: Concept
type: Group (social concept)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0086409
comment: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term, "Spanish origin" can be used in addition to "Hispanic or Latino". (OMB) [Definition Source: NCI]

Excision of Cyst
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997755
comment: Surgical removal of a cyst.

Operative Procedure on Lumbosacral Spinal Structure
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997868
comment: Lumbo-sacral spine surgery

Surgical Procedure on Cervical Spine
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997463
comment: Surgical procedure on the cervical spine.

Operative Procedure on Thoracic Spinal Structure
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997608
comment: Thoracic spine surgery.

Gastryc Bypass
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017125
comment: Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption. [Definition Source: MSH]

Insertion of Implantable Intrathecal Access System
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2960489
comment: Surgical insertion of intrathecal access system for drug delivery.

Closed Fracture of Tibia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0159870
comment: A closed fracture of the tibia.
broader transitive: Tibia Fracture

Lumbar Spinal Fusion
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0186045
comment: Lumbar spinal fusion is surgery to join, or fuse, two or more vertebrae in the low back. The surgery is also called arthrodesis. [Defintion Source: myhealth.alberta.ca]

Emergency Tracheostomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0189343
comment: Surgical formation of an opening into the trachea through the neck, or the opening so created. [Definition Source: MSH]

Procedure on Pelvic Region of Trunk
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3661975
comment: Pelvic surgery.

Excision of dermatofibroma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3839771
comment: Surgical removal of dermatofibroma.

Intervertebral Disc Prolapse
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021818
comment: Herniated Disc [Definition Source: MedDRA]
broader transitive: Hernia

Repair of Bladder
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0194475
comment: Surgical repair of bladder

Appendectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003611
comment: Surgical removal of the vermiform appendix. [Definition Source: NCI]

Pneumonia Caused By SARS-CoV-2
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5244027
comment: Pneumonia caused by severe acute respiratory syndrome coronavirus 2 [Definition Source: SNOMEDCT]
broader transitive: Pneumonia

Leukoaraiosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0948163
comment: Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS. [Definition Source: MSH]
broader transitive: Finding

Transurethral Prostatectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040771
comment: Prostate tissue removal via a cystoscope. [Definition Source: NCI]

Neck Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027531
comment: General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck. [Defintion Source: MSH]
broader transitive: Head and Neck Finding

Herpes Simplex Keratitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019357
comment: A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) [Defintion Source: MSH]
broader transitive: Herpes Simplex Virus Infection
broader transitive: Keratitis

Gastroplasty
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017193
comment: Surgical procedures involving the STOMACH and sometimes the lower ESOPHAGUS to correct anatomical defects, or to treat MORBID OBESITY by reducing the size of the stomach. There are several subtypes of bariatric gastroplasty, such as vertical banded gastroplasty, silicone ring vertical gastroplasty, and horizontal banded gastroplasty. [Definition Source: MSH]

Two Vessel Coronary Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581375
comment: There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in two coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery). (ACC) [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Sign or Symptom
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037088
comment: Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). [Definition Source: NCI]
broader transitive: Finding

Third Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3639750
comment: Any individual related biologically or legally to another individual and considered two degrees removed from the immediate family as in the case of cousins. [Definition Source: NCI]

Spina Bifida
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0080178
comment: A congenital neural tube defect in which vertebrae are not fully formed. It results in the protrusion of the spinal cord through the opening of the vertebrae. [Definition Source: NCI]
broader transitive: Non-Neoplastic Central Nervous System Disorder

C9orf72 Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1428691
comment: This gene may play a role in cell death. [Definition Source: NCI]

SQSTM1 Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420393
comment: This gene is involved in signal transduction. [Definition Source: NCI]

Brother
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3830065
comment: A male who shares with his sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]
broader transitive: First Degree Relative

Sister
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3827310
comment: A female who shares with her sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]
broader transitive: First Degree Relative

Angioedema
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002994
comment: Rapid swelling of the deep layers of the skin due to transient vascular leakage of serous fluid. [Definition Source: NCI][attribution: NICHD]
broader transitive: Finding

Blepharitits
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005741
comment: Inflammation of the eyelids near the eyelashes. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Drug Hypersensitivity Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3541994
comment: A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Molluscum Contagiosum Virus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026394
comment: A species of enveloped and brick-shaped viruses in the Poxviridae family and Molluscipoxvirus genus. The genome is composed of non-segmented, linear double-stranded DNA. Molluscum contagiosum viruses are found in humans and can cause the disease Molluscum contagiosum. Molluscum contagiosum viruses are transmitted via direct person-to-person contact and contact with infected fomites. [Definition Source: NCI]

Tinea Versicolor
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040262
comment: A skin condition characterized by hypopigmented, pink or tan, confetti-like, discrete and confluent scaly macules distributed on the chest, shoulders and upper back. [Definition Source: NCI]
broader transitive: Disease or Disorder

Vitamin D Deficiency
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042870
comment: Abnormally low level of 25-hydroxyvitamin D in the blood. [Definition Source: NCI]
broader transitive: Disease or Disorder

Ureteral Stenosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0521618
comment: Narrowing of the luminal diameter of one or both ureters due to intrinsic factors. [Definition Source: NCI]
broader transitive: Disease or Disorder

Anosmia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003126
comment: Inability to smell. [Definition Source: NCI]
broader transitive: Finding

Ageusia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2364111
comment: Inability to taste. [Definition Source: NCI]
broader transitive: Finding

Subdural Hematoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018946
comment: A collection of blood between the dura mater and the brain. [Definition Source: NCI]
broader transitive: Finding

Cognitive Impariment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338656
comment: Diminished mental function. [Definition Source: NCI]
broader transitive: Finding

Migraine With Aura
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0154723
comment: A migraine disorder characterized by episodes that are preceded by focal neurological symptoms. [Definition Source: NCI]
broader transitive: Migraine

Post-Herpetic Neuralgia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032768
comment: Pain that occurs after the disappearance of herpes zoster infection lesions. [Definition Source: NCI]
broader transitive: Symptom

Blepharospasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005747
comment: Involuntary twitching of the eyelid. [Definition Source: NCI]
broader transitive: Head and Neck Finding

OPTN Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1424774
comment: This gene plays a role in both neuroprotection and Golgi maintenance [Definition Source: NCI]

Dog Bite
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0259797
comment: A wound received from the teeth of a dog. [Definition Source: NCI]
broader transitive: Injury

Cholelithiasis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008350
comment: The presence of calculi in the gallbladder. [Definition Source: NCI]
broader transitive: Disease or Disorder

DCTN1 Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1413935
comment: This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles. [Definition Source: NCI]

Acute Pyelonephritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0520575
comment: Sudden onset pyelonephritis. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Macular Degeneration
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024437
comment: Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [Definition Source: NCI]
broader transitive: Disease or Disorder

Eye
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015392
comment: The organ of sight or vision. [Definition Source: NCI]

Head
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018670
comment: The anterior and superior part of a human bearing the mouth, the brain and sensory organs. [Definition Source: NCI]

Limb
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015385
comment: A body region referring to an upper or lower extremity. [Definition Source: NCI]

Bone Marrow
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005953
comment: The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. [Definition Source: NCI]

Brain
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006104
comment: An organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium. [Definition Source: NCI]

Brain Stem
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006121
comment: Three sections, the midbrain, pons and medulla oblongata, that are located at the base of the brain. The brain stem regulates the central nervous system, and is vital as a conduit for motor and sensory innervations. [Definition Source: NCI]

Cerebellum
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007765
comment: The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement. [Definition Source: NCI]

Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037925
comment: The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. [Definition Source: NCI][attribution: On-line Medical Dictionary]

Supratentorial Brain
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522407
comment: The part of the brain that is located superior to the tentorium cerebelli. [Definition Source: NCI]

Abdomen
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0230168
comment: The cavity located between the lungs and pelvis. It contains the lower esophagus, stomach, pancreas, intestines, liver, gallbladder and spleen. [Definition Source: NCI]

Upper Extremity
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1140618
comment: The region of the body that includes the arm, the forearm, and hand. [Definition Source: NCI]
broader transitive: Limb

Lower Extremity
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023216
comment: The limb that is composed of the hip, thigh, leg and foot. [Definition Source: NCI]
broader transitive: Limb

Pelvis
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030797
comment: The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. [Definition Source: NCI]

Thorax
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0817096
comment: The division of the body lying between the neck and the abdomen. [Definition Source: NCI]

Viral Pericarditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0276139
comment: Pericarditis that is caused by an infection with a viral agent. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cervical Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581619
comment: The portion of the spinal cord located in the cervical region. [Definition Source: NCI]

Thoracic Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581620
comment: The portion of the spinal cord located in the thoracic region. [Definition Source: NCI]

Acquired Hypothyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0700502
comment: Hypothyroidism, the cause of which is not present at birth. [Definition Source: NCI]
broader transitive: Hypothyroidism

Primary Lateral Sclerosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0154682
comment: A progressive neurodegenerative disorder affecting upper motor neurons, characterized by progressive muscle weakness. [Definition Source: NCI]
broader transitive: Motor Neuron Disease

Vertebral Column
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037949
comment: A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. [Definition Source: NCI]

Neck
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027530
comment: The region that connects the head to the rest of the body. [Definition Source: NCI]

L4-L5 Intervertebral Space
type: NamedIndividual
type: Concept
type: Anatomic Site
comment: The space between the L4 and L5 vertebrae. [Definition Source: NCI]

Recurrent Acute Myeloid Leukemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1142169
comment: The reemergence of acute myeloid leukemia after a period of remission. [Definition Source: NCI]
broader transitive: Acute Myeloid Leukemia

Dietary Supplement
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242295
comment: Oral preparations containing dietary ingredient(s) intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites. [Definition Source: NCI]
note: Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30.

Plasmapheresis
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: A procedure that collects plasma from the peripheral blood while returning the rest to the donor. [Definition Source: NCI]
broader transitive: Immunoactive Drugs

Transplantation
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040732
comment: Transference of a tissue or organ within an individual, between individuals of the same species, or between individuals of different species. [Definition Source: NCI]

Conization
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0195324
comment: Surgical removal of a cone-shaped portion of tissue from the uterine cervix. [Definition Source: NCI]

Head and Neck Surgery
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1512343
comment: Any surgery involving a structure in the head and neck region. [Definition Source: NCI]
broader transitive: Head and Neck Approaches

Herpes Simplex Virus Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019348
comment: An infection that is caused by herpes simplex virus. [Definition Source: NCI]
broader transitive: Disease or Disorder

Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007117
comment: A carcinoma involving the basal cells. [Definition Source: NCI]
broader transitive: Carcinoma

Opioid Use Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4324621
comment: The use of opioids that results in the development of a dependency that adversely affects an individual's life. [Definition Source: NCI]

Pneumococcal Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155862
comment: Pneumonia that is attributed to the bacteria Streptococcus pneumonia. [Definition Source: NCI]
broader transitive: Pneumonia

COVID-19 Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5203670
comment: An acute infection of the respiratory tract that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on currently available information, SARS-CoV-2 is thought to mainly spread from person to person through respiratory droplets. Typically, there is a two- to 14-day incubation period and infected persons can present with no symptoms or mild to severe fever, dry cough, fatigue, and difficulty breathing. Dysgeusia, anosmia, and gastrointestinal and flu-like symptoms have also been reported. Older adults and persons of any age who have serious underlying medical conditions may be of higher risk for severe illness, including secondary infections, respiratory failure, and multi-organ dysfunction. [Definition Source: NCI]
broader transitive: Disease or Disorder

Thoracic Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039980
comment: Trauma to the chest. [Definition Source: NCI]
broader transitive: Injury

Non-Invasive Mechanical Ventilation (NIV)
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2349740
comment: A type of mechanical ventilation procedure that uses a non-invasive means, such as a face mask or nasal mask, to deliver oxygenated air into the lungs. [Definition Source: NCI]

MTHFR Gene Mutation
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3805092
comment: A change in the nucleotide sequence of the MTHFR gene. [Definition Source: NCI]

Hepatic Toxicity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0235378
comment: Toxicity that impairs or damages the liver. [Definition Source: NCI]
broader transitive: Injury

Second Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1519210
comment: Any relative who is two meioses away from a particular individual in a family; a relative with whom one quarter of an individual's genes is shared (i.e., grandparent, grandchild, uncle, aunt, nephew, niece, half-sibling) (from Genetics Home Reference glossary) [Definition Source: NCI]

Discectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0206078
comment: Surgical excision of an intervertebral disc. Often performed for pain relief. [Definition Source: NCI]

First Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1517194
comment: Any relative who is one meiosis away from a particular individual in a family; a relative with whom one half of an individual's genes is shared (i.e., parent, sibling, offspring) (from Genetics Home Reference glossary) [Definition Source: NCI]

TBK1 Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1336579
comment: This gene plays a role in the immune response and signal transduction. [Definition Source: NCI]

Daughter
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337552
comment: A female human offspring. [Definition Source: NCI]
broader transitive: First Degree Relative

Father
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015671
comment: A male parent. [Definition Source: NCI]
broader transitive: First Degree Relative

Mother
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026591
comment: A female parent. [Definition Source: NCI]
broader transitive: First Degree Relative

Son
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037683
comment: A male human offspring. [Definition Source: NCI]
broader transitive: First Degree Relative

Anticonvulsant Agent
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Medicine to stop, prevent, or control seizures (convulsions). [Definition Source: NCI]
broader transitive: Drugs for Other Diseases

Abdominal Pain
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000737
comment: Painful sensation in the abdominal region. [Definition Source: NCI]
broader transitive: Symptom

Bacterial Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004626
comment: Acute infection of the lung parenchyma caused by bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila). Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. [Definition Source: NCI]
broader transitive: Pneumonia

Celiac Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007570
comment: An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [Definition Source: NCI]
broader transitive: Disease or Disorder

Chalazion
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007933
comment: An eyelid cyst caused by the blockage of a meibomian gland. [Definition Source: NCI]
broader transitive: Disease or Disorder

Type 2 Diabetes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011860
comment: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity. [Definition Source: NCI]
broader transitive: Diabetes Mellitus

Cranial Nerve VII Palsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015469
comment: Partial or complete paralysis of the facial muscles of one side of a person's face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur. [Definition Source: NCI]
broader transitive: Disease or Disorder

Femur Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015802
comment: A traumatic or pathologic injury to the femur in which the continuity of the femur is broken. [Definition Source: NCI]
broader transitive: Injury

Gastritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017152
comment: Inflammation of the stomach. [Definition Source: NCI]
broader transitive: Disease or Disorder

Gastroesophageal Reflux Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017168
comment: A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. [Definition Source: NCI]
broader transitive: Disease or Disorder

Glaucoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017601
comment: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hypothyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020676
comment: Abnormally low levels of thyroid hormone. [Definition Source: NCI][attribution: NICHD]
broader transitive: Thyroid Gland Disorder

Keratitis
type: NamedIndividual
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022568
comment: Inflammation of the cornea. [Definition Source: NCI]
broader transitive: Disease or Disorder

Keratoconus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022578
comment: A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances. [Definition Source: NCI]
broader transitive: Disease or Disorder

Progressive Multifocal Leukoencephalopathy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023524
comment: A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection. [Definition Source: NCI]
broader transitive: Disease or Disorder

Leukopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0750394
comment: A laboratory test result indicating a decreased number of white blood cells in the peripheral blood. [Definition Source: NCI]
broader transitive: Finding

Lymphopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0853986
comment: An abnormally small number of lymphocytes in the circulating blood. [Definition Source: NCI]
broader transitive: Leukopenia

Nervous System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027765
comment: A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves. [Definition Source: NCI]
broader transitive: Disease or Disorder

Parkinson's Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030567
comment: A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. [Definition Source: NCI]
broader transitive: Extrapyramidal Disorder

Pityriasis Rosea
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032026
comment: A mild, self-limited skin disorder that is most commonly seen in children and young adults. It is characterized by an initial large round spot on the chest, abdomen, or back, often referred to as a herald patch, that is usually followed within a week by a distinctive pattern of similar but smaller papules on the torso, arms, and legs. There may also be itching, especially when overheated. [Definition Source: NCI]
broader transitive: Disease or Disorder

Retinal Detachment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035305
comment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision. [Definition Source: NCI]
broader transitive: Disease or Disorder

Sjogren Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1527336
comment: An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus. [Definition Source: NCI]
broader transitive: Autoimmune Disease

Thyroid Gland Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040128
comment: A non-neoplastic or neoplastic disorder that affects the thyroid gland. Representative examples include hyperthyroidism, hypothyroidism, thyroiditis, follicular adenoma, and carcinoma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Thyroiditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040147
comment: Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis. [Definition Source: NCI]
broader transitive: Thyroid Gland Disorder

Urinary Stone
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042018
comment: A concretion in the urinary tract. [Definition Source: NCI]

Vitiligo
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042900
comment: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Fever Chills
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085594
comment: Shivering secondary to a febrile process. [Definition Source: NCI]
broader transitive: Symptom

Acute Cystitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149523
comment: An acute infection of the bladder. It is usually caused by bacteria. Signs and symptoms include increased frequency of urination, pain or burning during urination, fever, cloudy or bloody urine, and suprapubic pain. [Definition Source: NCI]
broader transitive: Disease or Disorder

Alanine Aminotransferase Increased
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0151905
comment: An increase in the level of alanine aminotransferase in the blood. [Definition Source: NCI]
broader transitive: Finding

Trigeminal Nerve Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0152177
comment: A non-neoplastic or neoplastic disorder affecting the trigeminal nerve (fifth cranial nerve). [Definition Source: NCI]
broader transitive: Disease or Disorder

Ankle Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0159877
comment: Traumatic or pathological injury to the ankle joint in which the continuity of an ankle bone is broken. Symptoms include pain, swelling, and difficulty moving the affected leg and foot. [Definition Source: NCI]
broader transitive: Injury

Interstitial Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0206061
comment: Inflammation of interstitial lung tissue, usually associated with infection. [Definition Source: NCI]
broader transitive: Pneumonia

Female Reproductive System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0236100
comment: A non-neoplastic or neoplastic disorder that affects the female genital system. Representative examples of non-neoplastic disorders include infection, endometriosis, and adenomyosis. Representative examples of neoplastic disorders include germ cell tumors, carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Acute Respiratory Failure
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0264490
comment: Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock. [Definition Source: NCI]
broader transitive: Disease or Disorder

Obstructive Sleep Apnea Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0520679
comment: A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hashimoto Thyroiditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677607
comment: An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism. [Definition Source: NCI]
broader transitive: Thyroiditis

Rheumatologic Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035435
comment: Inflammatory and degenerative diseases of connective tissue structures, such as arthritis. [Definition Source: NCI]
broader transitive: Disease or Disorder

Viral Respiratory Tract Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0877203
comment: A respiratory tract infection caused by a virus. Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus. [Definition Source: NCI]
broader transitive: Disease or Disorder

Non-Neoplastic Central Nervous System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1335000
comment: Any disorder other than abnormal tissue growth resulting from uncontrolled cell proliferation affecting the nervous system.
broader transitive: Nervous System Disorder
broader transitive: Disease or Disorder

Myocardial Infarction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027051
comment: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis. [Definition Source: NCI]
broader transitive: Disease or Disorder

Thromboembolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040038
comment: Occlusion of the lumen of a vessel by a thrombus that has migrated from a distal site via the blood stream. [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Insomnia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0917801
comment: A sleep disorder characterized by difficulty in falling asleep and/or remaining asleep. [Definition Source: NCI]
broader transitive: Disease or Disorder

Sphincter
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1409894
comment: A circular band of muscle that functions to regulate the size of an orifice in the body. [Definition Source: NCI]

Asthma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004096
comment: A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [Definition Source: NCI]
broader transitive: Chronic Lung Disorder

Acquired Immunodeficiency Syndrome (AIDS)
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001175
comment: A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin lymphoma and Kaposi sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood. [Definition Source: NCI]
broader transitive: Disease or Disorder

Adenocarcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001418
comment: A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. [Definition Source: NCI]
broader transitive: Carcinoma

AR Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1367578
comment: This gene plays a role in the transcriptional activation of androgen responsive genes. [Definition Source: NCI]

Alzheimer's Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002395
comment: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. [Definition Source: NCI]
broader transitive: Dementia

Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002871
comment: A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. [Definition Source: NCI]
broader transitive: Disease or Disorder

Anorexia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
comment: Loss of appetite. [Definition Source: NCI]
comment: https://uts.nlm.nih.gov/uts/umls/concept/C1971624
broader transitive: Disease or Disorder

Anxiety Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003469
comment: A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [Definition Source: NCI]
broader transitive: Psychiatric Disorder

Arrhythmia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003811
comment: Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003864
comment: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. [Definition Source: NCI]
broader transitive: Disease or Disorder

Rheumatoid Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003873
comment: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. [Definition Source: NCI]
broader transitive: Arthritis
broader transitive: Autoimmune Disease

Autoimmune Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004364
comment: A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis). [Definition Source: NCI]
broader transitive: Disease or Disorder

Psychiatric Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004936
comment: A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [Definition Source: NCI]
broader transitive: Disease or Disorder

Benign Prostatic Hyperplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1704272
comment: A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow. [Definition Source: NCI]
broader transitive: Disease or Disorder

Vulvovaginal Candidiasis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006852
comment: Infection of the vulva and vagina with a fungus of the genus CANDIDA. It is a disease associated with HIV infection. [Definition Source: NCI]
broader transitive: Disease or Disorder

Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007097
comment: A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. [Definition Source: NCI]
broader transitive: Malignant Neoplasm

Malignant Skin Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007114
comment: A primary or metastatic malignant neoplasm involving the skin. Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. [Definition Source: NCI]
broader transitive: Malignant Neoplasm

Skin Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007117
comment: The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas. [Definition Source: NCI]
broader transitive: Basal Cell Carcinoma

Skin Basosquamous Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007118
comment: A basal cell carcinoma which displays squamous differentiation. The neoplastic cells have more abundant cytoplasm with more marked keratinization than typical basal cell carcinomas. It usually has a more aggressive clinical course compared to typical basal cell carcinoma, and it may produce regional or widespread metastases. [Definition Source: NCI]
broader transitive: Skin Basal Cell Carcinoma

Cardiovascular Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007222
comment: A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Colorectal Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009402
comment: A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [Definition Source: NCI]
broader transitive: Neoplasm

Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010709
comment: A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. [Definition Source: NCI]
broader transitive: Finding

Depression
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011570
comment: A melancholy feeling of sadness and despair. [Definition Source: NCI]
broader transitive: Mood Disorder

Diabetes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011849
comment: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. [Definition Source: NCI]
broader transitive: Disease or Disorder

Type 1 Diabtes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011854
comment: A chronic condition characterized by minimal or absent production of insulin by the pancreas. [Definition Source: NCI][attribution: NICHD]
broader transitive: Autoimmune Disease
broader transitive: Diabetes Mellitus

Mumps
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026780
comment: A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. [Definition Source: NCI]
broader transitive: Disease or Disorder

Disease or Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012634
comment: Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. [Definition Source: NCI]

Eczema
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013595
comment: A form of dermatitis characterized by red, itchy, scaly, or crusty patches that can be chronic or intermittent. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Endometriosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014175
comment: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. [Definition Source: NCI]
broader transitive: Disease or Disorder

Seizure Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014544
comment: A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. [Definition Source: NCI]
broader transitive: Disease or Disorder

Generalized Epilepsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014548
comment: A chronic condition characterised by recurrent generalised seizures. [Definition Source: NCI]
broader transitive: Seizure Disorder

Fibroma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016045
comment: A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts. [Definition Source: NCI]
broader transitive: Disease or Disorder

Heart Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018799
comment: A non-neoplastic or neoplastic disorder that affects the heart and/or the pericardium. Representative examples include endocarditis, pericarditis, atrial myxoma, cardiac myeloid sarcoma, and pericardial malignant mesothelioma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cavernous Hemangioma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018920
comment: A hemangioma characterized by the presence of cavernous vascular spaces. [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Hepatitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019158
comment: Inflammation of the liver; usually from a viral infection, but sometimes from toxic agents. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hepatitis A Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019159
comment: Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hepatitis C Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019196
comment: A viral infection caused by the hepatitis C virus. [Definition Source: NCI]
broader transitive: Disease or Disorder

Langerhans Cell Histiocytosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019621
comment: A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001) [Definition Source: NCI]
broader transitive: Disease or Disorder

Hypersensitivity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020517
comment: An immune response that occurs following exposure to an innocuous antigen, but that does not require the presence of preformed antibodies to the antigen. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hypertension
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020538
comment: Blood pressure that is abnormally high. [Definition Source: NCI]
broader transitive: Finding

Hypertensive Crisis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020546
comment: A severe, acute increase in blood pressure that may result in stroke or myocardial ischemia. [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Hyperthyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020550
comment: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor. [Definition Source: NCI]
broader transitive: Thyroid Gland Disorder

Hypertrophy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020564
comment: Abnormal enlargement of a body part or organ. [Definition Source: NCI]
broader transitive: Disease or Disorder

Epidermal Inclusion Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014511
comment: The most common type of cutaneous cyst. It results from the proliferation of epidermal cells in a circumscribed space within the dermis. It is usually asymptomatic and presents as a firm, round nodule. [Definition Source: NCI]
broader transitive: Cyst

Acute Myeloid Leukemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023467
comment: A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias (AMLs) encompasses four major categories: 1) AML with recurrent genetic abnormalities; 2) AML with multilineage dysplasia; 3) Therapy-related AML; 4) AML not otherwise specified. The required bone marrow or peripheral blood blast percentage for the diagnosis of AML is 20% (WHO classification). [Definition Source: NCI]
broader transitive: Disease or Disorder

Chronic Obstructive Pulmonary Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024117
comment: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema. [Definition Source: NCI]
broader transitive: Disease or Disorder

Non-Hodgkin Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024305
comment: Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage. [Definition Source: NCI]
broader transitive: Disease or Disorder

Multiple Sclerosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026769
comment: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [Definition Source: NCI]
broader transitive: Non-Neoplastic Central Nervous System Disorder
broader transitive: Autoimmune Nervous System Disorder

Fungal Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026946
comment: An infection caused by a fungus. [Definition Source: NCI]
broader transitive: Disease or Disorder

Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0375111
comment: A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. [Definition Source: NCI]
broader transitive: Disease or Disorder

Obesity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0028754
comment: Having a high amount of body fat (body mass index [BMI] of 30 or more). [Definition Source: NCI]
broader transitive: Finding

Osteoporosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0029456
comment: A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). [Definition Source: NCI]
broader transitive: Disease or Disorder

Pituitary Neuroendocrine Tumor
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032000
comment: A well-differentiated neuroendocrine neoplasm that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. It has a low frequency of metastatic spread. When metastatic, the term metastatic pituitary neuroendocrine tumor is endorsed instead of pituitary carcinoma. (WHO) [Definition Source: NCI] It has exact synonim: Pituitary Gland Adenoma.
broader transitive: Disease or Disorder

Pleural Effusion
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032227
comment: Increased amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough, and chest pain. It is usually caused by lung infections, congestive heart failure, pleural and lung tumors, connective tissue disorders, and trauma. [Definition Source: NCI]
broader transitive: Finding

Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032285
comment: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. [Definition Source: NCI]
broader transitive: Disease or Disorder

Psoriasis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033860
comment: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp. [Definition Source: NCI][attribution: NICHD]
broader transitive: Disease or Disorder

Septicemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036690
comment: The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention. [Definition Source: NCI]
broader transitive: Disease or Disorder

Finding
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1285578
comment: Clinical, laboratory or molecular evidence, or absence of evidence of disease. [Definition Source: NCI]

Stroke
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0038454
comment: A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event. [Definition Source: NCI]
broader transitive: Non-Neoplastic Central Nervous System Disorder

Thrombocytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0392386
comment: A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. [Definition Source: NCI]
broader transitive: Finding

Toxoplasmosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040558
comment: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. [Definition Source: NCI]
broader transitive: Disease or Disorder

Urticaria
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042109
comment: A transient, itchy skin eruption characterized by wheals with pale interiors and red margins. [Definition Source: NCI]
broader transitive: Disease or Disorder

Uterine Corpus Leiomyoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042133
comment: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [Definition Source: NCI]
broader transitive: Disease or Disorder

Congenital Adrenal Hyperplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001627
comment: A genetic disorder characterized by defects in the synthesis of cortisol and/or aldosterone, resulting in hyperplasia of the adrenal cortical cells. [Definition Source: NCI]
broader transitive: Disease or Disorder

Amyotrophic Lateral Sclerosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002736
comment: A neurodegenerative disorder characterized by progressive degeneration of the motor neurons of the central nervous system. It results in weakness and atrophy of the muscles which leads to an inability to initiate and control voluntary movements. [Definition Source: NCI]
broader transitive: Motor Neuron Disease
broader transitive: Central Nervous System Degenerative Disorder

Hereditary Hemolytic Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002881
comment: A congenital hemolytic anemia caused by defects of the erythrocyte membrane, enzyme deficiencies, or hemoglobinopathies. [Definition Source: NCI]
broader transitive: Anemia

Bipolar Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005586
comment: A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression. [Definition Source: NCI]
broader transitive: Mood Disorder

Closed Dislocation of Shoulder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0434579
comment: A closed dislocation of the shoulder [Definition Source: NCI]
broader transitive: Shoulder Dislocation

Common Bile Duct Stone
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009438
comment: The presence of one or more stones in the common bile duct. They are composed either of cholesterol or, less commonly, calcium salts and bilirubin. [Definition Source: NCI]

B-Cell Non-Hodgkin Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0079731
comment: The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. [Definition Source: NCI]
broader transitive: Non-Hodgkin Lymphoma

Favism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015702
comment: A condition associated with glucose-6-phosphate dehydrogenase deficiency, which is characterized by hemolysis. [Definition Source: NCI]
broader transitive: Anemia

Gastroenteritits
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017160
comment: An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. [Definition Source: NCI]
broader transitive: Disease or Disorder

Head Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018674
comment: A traumatic injury to the head. [Definition Source: NCI]
broader transitive: Head and Neck Finding

Headache
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018681
comment: Pain in various parts of the head, not confined to the area of distribution of any nerve. [Definition Source: NCI]
broader transitive: Finding

Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019270
comment: The protrusion of part of an organ or fibroadipose tissue through an abnormal opening. [Definition Source: NCI]
broader transitive: Disease or Disorder

Palmar Fibromatosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013312
comment: A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males. [Definition Source: NCI] It has exact synonim: Dupuytren Contracture; Palmar Fibromatosis; Dupuytren's Contracture.
broader transitive: Disease or Disorder

Inguinal Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019294
comment: The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region. [Definition Source: NCI]
broader transitive: Hernia

Cold Sore
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019345
comment: A lesion caused by type 1 or type 2 herpes simplex virus, involving the oralfacial region. [Definition Source: NCI]
broader transitive: Herpes Simplex Virus Infection

Infectious Mononucleosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021345
comment: A clinical syndrome of fever, sore throat, fatigue, and lymphadenopathy caused by infection with the Epstein-Barr virus. Subsequent physical findings may include hepatomegaly, palatal petechiae, jaundice, uvular edema, and splenomegaly. [Definition Source: NCI]
broader transitive: Disease or Disorder

Intestinal Pseudo-Obstruction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021847
comment: Ileus of the intestine in which there is no mechanical obstruction. [Definition Source: NCI]
broader transitive: Disease or Disorder

Iridocyclitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022073
comment: Inflammation of the iris and the ciliary body. [Definition Source: NCI]
broader transitive: Disease or Disorder

Knee Injury
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022744
comment: Trauma to the knee. [Definition Source: NCI]
broader transitive: Injury

Essential Hypertension
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085580
comment: Hypertension that presents without an identifiable cause. [Definition Source: NCI]
broader transitive: Hypertension

Long QT Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023976
comment: A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hip Osteoarthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0029410
comment: Osteoarthritis of the hip joint. [Definition Source: NCI]
broader transitive: Arthritis

Pancytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030312
comment: A finding of low numbers of red and white blood cells and platelets in the peripheral blood. [Definition Source: NCI]
broader transitive: Finding

Panic Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030319
comment: An anxiety disorder characterized by multiple unexpected panic attacks with persistent concern of recurring attacks. Panic disorder may or may not be accompanied by agoraphobia. [Definition Source: NCI]
broader transitive: Anxiety Disorder

Penicillin Allergy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030824
comment: An allergy to Penicillin. [Definition Source: NCI]
broader transitive: Drug Hypersensitivity Syndrome

Personality Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031212
comment: A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work. [Definition Source: NCI]
broader transitive: Psychiatric Disorder

Aspiration Pneumonitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1761609
comment: Inflammation of the lungs due to the inhalation of solid or liquid material. [Definition Source: NCI]
broader transitive: Disease or Disorder

Baker Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032650
comment: Swelling and protrusion of the gastrocnemius-semimembranosus bursa due to an accumulation of synovial fluid. [Definition Source: NCI]
broader transitive: Cyst

Sarcoidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036202
comment: An idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, and skin. Cardiac involvement is also possible. [Definition Source: NCI]
broader transitive: Disease or Disorder

Pulmonary Sarcoidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036205
comment: Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss. [Definition Source: NCI]
broader transitive: Sarcoidosis
broader transitive: Chronic Lung Disorder

Shoulder Dislocation
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037005
comment: A dislocation of the shoulder joint. [Definition Source: NCI]
broader transitive: Injury

Sinusitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037199
comment: An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity. [Definition Source: NCI]
broader transitive: Disease or Disorder

Staphylococcal Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0038160
comment: Infection by Staphylococcus. [Definition Source: NCI]
broader transitive: Disease or Disorder

Syncope
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039070
comment: A spontaneous loss of consciousness caused by insufficient blood supply to the brain. [Definition Source: NCI]
broader transitive: Finding

Thalassemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039730
comment: An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cutaneous Melanoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0151779
comment: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma. [Definition Source: NCI]
broader transitive: Malignant Skin Neoplasm

Vulvovaginitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042998
comment: An inflammatory pathologic process that affects the vulva and the vagina. [Definition Source: NCI]
broader transitive: Disease or Disorder

Acute Myocardial Infarction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155626
comment: Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [Definition Source: NCI]
broader transitive: Disease or Disorder

Closed Fracture of Rib
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0435750
comment: A traumatic break in one of the bones in the rib cage that does not involve a break in the adjacent skin. [Definition Source: NCI]
broader transitive: Injury

Tooth Abscess
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0518988
comment: An infectious process that affects a tooth. It is characterized by localized periapical or periodontal collection of pus. It presents with pain and swelling of the gums and/or cheek. [Definition Source: NCI]
broader transitive: Disease or Disorder

Monoclonal Gammopathy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1136085
comment: An abnormal laboratory test result indicating the presence of monoclonal immunoglobulins in the blood or urine. [Definition Source: NCI]
broader transitive: Finding

Head and Neck Finding
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0575141
comment: Symptoms, physical examination results, and/or laboratory test results related to the head and neck. [Definition Source: NCI]
broader transitive: Finding

Injury
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3263723
comment: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]
broader transitive: Finding

Bradycardia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0428977
comment: An abnormally slow heart rate. Thresholds for different age, gender, and patient populations exist. [Definition Source: NCI]
broader transitive: Arrhythmia

Hypercholesterolemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522133
comment: A laboratory test result indicating an increased amount of cholesterol in the blood. [Definition Source: NCI]
broader transitive: Finding

Proteinuria
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033687
comment: The presence of abnormal amounts of protein in the urine. [Definition Source: NCI]
broader transitive: Finding

Vertigo
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042571
comment: A feeling of movement, a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). Vertigo is medically distinct from dizziness, lightheadedness, and unsteadiness. [Definition Source: NCI]
broader transitive: Finding

Menopausal Symptom
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0236075
comment: Any of the mental or physical manifestations that accompany perimenopause and menopause. [Definition Source: NCI]
broader transitive: Symptom

Skin Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0241060
comment: A cystic lesion located in the skin. [Definition Source: NCI]
broader transitive: Cyst

Breast Ductal Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1527349
comment: A breast carcinoma arising from the ducts. While ductal carcinomas can arise at other sites, this term is universally used to refer to carcinomas of the breast. Ductal carcinomas account for about two thirds of all breast cancers. Two types of ductal carcinomas have been described: ductal carcinoma in situ (DCIS) and invasive breast carcinoma of no special type. The latter often spreads to the axillary lymph nodes and other anatomic sites. The two forms of ductal carcinoma often coexist. [Definition Source: NCI]
broader transitive: Breast Carcinoma

High Grade Cervical Squamous Intraepithelial Neoplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1512433
comment: A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium. [Definition Source: NCI]
broader transitive: Disease or Disorder

Myeloproliferative Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1292778
comment: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008) [Definition Source: NCI]
broader transitive: Neoplasm

Colon Adenocarcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338106
comment: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. [Definition Source: NCI]
broader transitive: Adenocarcinoma

Dementia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0497327
comment: Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders. [Definition Source: NCI]
broader transitive: Central Nervous System Degenerative Disorder

Central Nervous System Degenerative Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0270715
comment: A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [Definition Source: NCI]
broader transitive: Non-Neoplastic Central Nervous System Disorder

Colon Dysplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1302363
comment: A morphologic finding indicating the presence of dysplastic glandular epithelial cells in the colonic mucosa. There is no evidence of invasion. [Definition Source: NCI]
broader transitive: Disease or Disorder

Breast Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0678222
comment: A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [Definition Source: NCI]
broader transitive: Carcinoma

Symptom
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1457887
comment: Subjective evidence of disease perceived by the patient. [Definition Source: NCI]
broader transitive: Sign or Symptom

Lumbosacral Region
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024094
comment: The part of the spine in the lower back that consists of the lumbar region and the sacrum. [Definition Source: NCI]

Skin Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0699893
comment: A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma. [Definition Source: NCI]
broader transitive: Carcinoma
broader transitive: Malignant Skin Neoplasm

Deep Vein Thrombosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149871
comment: A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. [Definition Source: NCI][attribution: NICHD]
broader transitive: Cardiovascular Disorder

Atrial Fibrillation
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004238
comment: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC) [Definition Source: NCI]
broader transitive: Arrhythmia

Diabetic Ketoacidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011880
comment: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids. [Definition Source: NCI]
broader transitive: Finding

Heart Failure
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018801
comment: Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hematoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018944
comment: A localized collection of blood, usually clotted, in an organ, space, or tissue, due to a break in the wall of a blood vessel. [Definition Source: NCI]
broader transitive: Finding

Lumbar Puncture Headache
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0270697
comment: Headache in erect position, after lumbar puncture; due to lowering of intracranial pressure by leakage of cerebrospinal fluid through the needle tract. [Definition Source: NCI]
broader transitive: Headache

Neonatal Hearing Impairment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1709158
comment: An abnormality that affects hearing within the first month after birth. It may or may not result in hearing loss. [Definition Source: NCI]
broader transitive: Disease or Disorder

Pulmonary Embolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034065
comment: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung. [Definition Source: NCI]
broader transitive: Cardiovascular Disorder

Transient Ischemic Attack
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007787
comment: A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. [Definition Source: NCI]
broader transitive: Non-Neoplastic Central Nervous System Disorder

Atrial Flutter
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004239
comment: A disorder characterized by an electrocardiographic finding of an organized, regular atrial rhythm with atrial rate of 240-340 beats per minute. Multiple P waves typically appear in the inferior leads in a saw tooth-like pattern between the QRS complexes. (CDISC) [Definition Source: NCI]
broader transitive: Arrhythmia

Pulmonary Insufficiency
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035229
comment: Impairment of gas exchange within the lungs secondary to a disease process, neoplasm, or trauma, possibly resulting in hypoxia, hypercarbia, or both, but not requiring intubation or mechanical ventilation. Patients are normally managed with pharmaceutical therapy, supplemental oxygen, or both. [Definition Source: NCI]
broader transitive: Disease or Disorder

Salpingectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0041271
comment: Surgery to remove part or all of the fallopian tube(s). [Definition Source: NCI]

Turbinectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0161872
comment: Total or partial excision of the turbinates. [Definition Source: NCI]

Sign
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0311392
comment: Objective evidence of disease perceptible to the examining healthcare provider. [Definition Source: NCI]
broader transitive: Sign or Symptom

SOD1 Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420306
comment: This gene plays a role in the detoxification of superoxide radicals in the cytosol. [Definition Source: NCI]

Serum Glutamic Pyruvic Transaminase, CTCAE
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1557189
comment: An enzyme that is normally present in liver and heart cells. SGPT is released into blood when the liver or heart is damaged. The blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Also called alanine aminotransferase (ALT). [Definition Source: RxList] Common Terminology Criteria for Adverse Events (CTCAE) [Definition Source: U.s. Department of Health and Human Services]
broader transitive: Finding

Anorectal Fistula
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149889
comment: A pathologic tract that connects an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess. [Definition Source: NCI]
broader transitive: Disease or Disorder

Myasthenia Gravis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026896
comment: A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction. [Definition Source: NCI]
broader transitive: Autoimmune Nervous System Disorder

Psoriatic Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003872
comment: Joint inflammation associated with psoriasis. [Definition Source: NCI]
broader transitive: Arthritis

Amenorrhea
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002453
comment: The absence of menses in a woman who has achieved reproductive age. [Definition Source: NCI]
broader transitive: Disease or Disorder

Alpha-Lipoic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023791
comment: A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. [Definition Source: NCI]
broader transitive: Dietary Supplement

Neurofibromatosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0162678
comment: An autosomal dominant hereditary neoplastic syndrome. Two distinct clinicopathological entities are recognized: neurofibromatosis type 1 and neurofibromatosis type 2. Neurofibromatosis type 1 is associated with the presence of cafe-au-lait cutaneous lesions, multiple neurofibromas, malignant peripheral nerve sheath tumors, optic nerve gliomas, and bone lesions. Neurofibromatosis type 2 is associated with the presence of schwannomas, meningiomas, and gliomas. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cervical Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0728985
comment: The set of vertebrae immediately caudal to the skull. [Definition Source: NCI]

Lumbar Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3887615
comment: Those vertebrae between the ribs and the pelvis, L1-L5 in man. [Definition Source: NCI]

Thoracic Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581269
comment: The vertebrae of the thoracic spine, numbered one through twelve in man. [Definition Source: NCI]

Serositis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036749
comment: Inflammation of a serous membrane. [Definition Source: NCI]
broader transitive: Disease or Disorder

Herpes Zoster
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019360
comment: A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. [Definition Source: NCI]
broader transitive: Disease or Disorder

Grandson
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337573
comment: A male grandchild. [Definition Source: NCI]
broader transitive: Second Degree Relative

Granddaughter
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337561
comment: A female grandchild. [Definition Source: NCI]
broader transitive: Second Degree Relative

Niece
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337578
comment: A daughter of your brother or sister. [Definition Source: NCI]
broader transitive: Second Degree Relative

Nephew
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337579
comment: A son of your brother or sister. [Definition Source: NCI]
broader transitive: Second Degree Relative

Cousin
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337580
comment: A child of your aunt or uncle or their descendents. [Definition Source: NCI]

First Cousin
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337583
comment: A child of your aunt or uncle. [Definition Source: NCI]
broader transitive: Third Degree Relative

Chronic Atropic Gastritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017154
comment: Atrophic gastritis that is persistent and long-standing. [Definition Source: NCI]
broader transitive: Gastritis

Malignant Thyroid Gland Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007115
comment: A primary or metastatic malignant neoplasm affecting the thyroid gland. [Definition Source: NCI]
broader transitive: Thyroid Gland Disorder

Melanocytic Nevus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027962
comment: A neoplasm composed of melanocytes that usually appears as a dark spot on the skin. [Definition Source: NCI]
broader transitive: Neoplasm

Flu-Like Symptoms
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0392171
comment: Complaints describing a pattern similar to influenza, which may include one or more of the following symptoms: fever, chills, muscle or body aches, cough, sore throat, rhinitis, or fatigue. [Definition Source: NCI]
broader transitive: Symptom

Psychosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033975
comment: A mental disorder characterized by personality change, impaired functioning, and loss of touch with reality. [Definition Source: NCI]
broader transitive: Psychiatric Disorder

Renal Colic
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0152169
comment: Paroxysmal and severe flank pain radiating to the inguinal area. It is caused by the passage of a kidney stone through the ureter. [Definition Source: NCI]
broader transitive: Disease or Disorder

Allergic Rhinitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2607914
comment: Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life. [Definition Source: NCI]
broader transitive: Disease or Disorder

Extrapyramidal Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015371
comment: A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia. Causes include vascular disorders, degenerative disorders, and antipsychotic drugs. [Definition Source: NCI]
broader transitive: Central Nervous System Degenerative Disorder

TARDBP Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420588
comment: This gene is involved in transcription and mRNA splicing. [Definition Source: NCI]

Monoclonal B_Cell Lymphocytosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2698259
comment: A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia. It precedes virtually all cases of chronic lymphocytic leukemia/small lymphocytic lymphoma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Dyslipidemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242339
comment: A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides. [Definition Source: NCI]
broader transitive: Finding

Intraepithelial Neoplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0878500
comment: A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia). [Definition Source: NCI]
broader transitive: Neoplasm

Iron-Deficiency Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0162316
comment: Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss. [Definition Source: NCI]
broader transitive: Anemia

Tetralogy of Fallot
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039685
comment: A congenital heart disorder characterized by the presence of the following four abnormalities: ventricular septal defect, pulmonary stenosis, overriding aorta, and right ventricular hypertrophy. [Definition Source: NCI]
broader transitive: Disease or Disorder

Brown-Sequard Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242644
comment: A disorder caused by a spinal injury leading to an incomplete spinal lesion. Patients develop paralysis, ataxia and loss of sensation. Causes include spinal cord tumors, spinal traumas, ischemia, and inflammatory processes affecting the spine. [Definition Source: NCI]
broader transitive: Disease or Disorder

Hereditary Factor XI Deficiency
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015523
comment: A rare inherited bleeding disorder caused by deficiency of coagulation factor XI. It may be asymptomatic or manifest with bleeding. [Definition Source: NCI]
broader transitive: Disease or Disorder

Frontotemporal Dementia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338451
comment: A syndrome caused by progressive degeneration of the frontal or temporal lobes of the brain. It is manifested with personality changes and deterioration of the language skills. [Definition Source: NCI]
broader transitive: Dementia

Hyperhomocysteinemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0598608
comment: A serious metabolic condition caused by mutations in the MTHFR gene, medications, or nutritional deficiency. It results in increased levels of homocysteine in the blood. Patients with this condition are at an increased risk for recurrent blood clots formation and cardiovascular accidents. [Definition Source: NCI]
broader transitive: Disease or Disorder

Ichthyosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020757
comment: A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe. [Definition Source: NCI]
broader transitive: Disease or Disorder

Ann Arbor Stage IV Mantle Cell Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677721
comment: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]
broader transitive: Disease or Disorder

Optic Neuritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0029134
comment: A disorder characterized by inflammation of the optic nerve. Causes include autoimmune disorders, infections, toxins, drugs, and multiple sclerosis. It may manifest with acute loss of vision and pain. [Definition Source: NCI]
broader transitive: Disease or Disorder

Primary Progressive Aphasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0282513
comment: A rare neurologic progressive disorder characterized by impairment of the language and speech abilities. [Definition Source: NCI]
broader transitive: Disease or Disorder

Progressive Bulbar Palsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030442
comment: A progressive motor neuron disorder affecting the muscles which are innervated by cranial nerves of the lower brain stem. Signs and symptoms include difficulties in chewing and swallowing, dysarthria, and weakness of the facial muscles and tongue. [Definition Source: NCI]
broader transitive: Motor Neuron Disease

Progressive Muscular Atrophy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0917981
comment: A rare, milder form of amyotrophic lateral sclerosis. It is characterized by a slowly progressive clinical course. Signs and symptoms include muscle weakness, atrophy, and fasciculation. [Definition Source: NCI]
broader transitive: Amyotrophic Lateral Sclerosis

Primary Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677930
comment: A tumor at the original site of origin. [Definition Source: NCI]
broader transitive: Neoplasm

Spinal and Bulbar Muscular Atrophy, X-linked 1
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1839259
comment: A rare, slowly progressive degenerative disorder affecting males. It is caused by mutations in the androgen receptor (AR) gene. It is characterized by bulbar and limb muscle weakness and atrophy, and gynecomastia. [Definition Source: NCI]
broader transitive: Disease or Disorder

Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0854831
comment: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cleft Palate
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008925
comment: A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. [Definition Source: NCI]
broader transitive: Disease or Disorder

Fibromyalgia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016053
comment: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation. [Definition Source: NCI]
broader transitive: Disease or Disorder

Migraine
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149931
comment: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cervical Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0302592
comment: A carcinoma arising from either the exocervical squamous epithelium or the endocervical glandular epithelium. The major histologic types of cervical carcinoma are squamous cell carcinoma and adenocarcinoma. [Definition Source: NCI]
broader transitive: Female Reproductive System Disorder
broader transitive: Carcinoma

Bowel Obstruction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021843
comment: Blockage of the normal flow of the intestinal contents within the bowel. [Definition Source: NCI]
broader transitive: Finding

FUS Gene
type: NamedIndividual
type: Concept
type: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1414860
comment: This gene is involved in gene expression, genomic integrity and RNA processing. [Definition Source: NCI]

Mood Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0525045
comment: A category of psychiatric disorders which have as their most predominant feature a disturbance in mood. [Definition Source: NCI]
broader transitive: Psychiatric Disorder

Malignant Colon Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007102
comment: A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]
broader transitive: Disease or Disorder

Gastroesophageal Reflux
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4317146
comment: The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). [Definition Source: NCI]
broader transitive: Finding

Alcohol Dependance
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001973
comment: Physical and psychological dependence on alcohol. [Definition Source: NCI]
broader transitive: Disease or Disorder

Malignant Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006826
comment: A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [Definition Source: NCI]
broader transitive: Neoplasm

Kidney Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1378703
comment: A carcinoma arising from the epithelium of the renal parenchyma or the renal pelvis. The majority are renal cell carcinomas. Kidney carcinomas usually affect middle aged and elderly adults. Hematuria, abdominal pain, and a palpable mass are common symptoms. [Definition Source: NCI]
broader transitive: Carcinoma

Scarlet Fever
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036285
comment: A streptococcal infection, mainly occurring among children, that is characterized by a red skin rash, sore throat, and fever. [Definition Source: NCI]
broader transitive: Disease or Disorder

Cervical Intraepithelial Neoplasia Grade 2/3
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2986622
comment: A neoplastic process in the cervix characterized by morphologic features of both moderate and severe intraepithelial neoplasia. [Definition Source: NCI]
broader transitive: Female Reproductive System Disorder

Aunt
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272868
comment: A female relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]
broader transitive: Second Degree Relative

Grandfather
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337477
comment: A male relative who is the biological father of either the biological mother or the biological father. [Definition Source: NCI]
broader transitive: Second Degree Relative

Grandmother
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337476
comment: A female relative who is the biological mother of either the biological mother or the biological father. [Definition Source: NCI]
broader transitive: Second Degree Relative

Maternal Aunt
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272872
comment: A female relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]
broader transitive: Aunt

Maternal Uncle
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272876
comment: A male relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]
broader transitive: Uncle

Paternal Aunt
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272877
comment: A female relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]
broader transitive: Aunt

Paternal Uncle
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272881
comment: A male relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]
broader transitive: Uncle

Uncle
type: NamedIndividual
type: Concept
type: KinshipType
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272882
comment: A male relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]
broader transitive: Second Degree Relative

Chicken Pox
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008049
comment: A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. [Definition Source: NCI]
broader transitive: Disease or Disorder

Acute Tonsillitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001361
comment: An acute inflammation of the tonsils caused by viruses or bacteria. Signs and symptoms include fever, enlargement of the tonsils, difficulty swallowing, and enlargement of the regional lymph nodes. [Definition Source: NCI]
broader transitive: Disease or Disorder

Chronic Lung Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0746102
comment: A persistent non-neoplastic disorder of the lungs. Representative examples include: chronic obstructive pulmonary disease, chronic bronchitis, emphysema, pulmonary fibrosis, pneumoconiosis, asbestosis, atelectasis, radiation induced pneumonitis, and radiation fibrosis. [Definition Source: NCI]
broader transitive: Disease or Disorder

Klippel-Feil Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022738
comment: A rare congenital syndrome characterized by the fusion of the vertebrae in the cervical spine. Patients present with a short neck and restricted mobility of the upper spine. Other signs and symptoms include scoliosis, spina bifida, cleft palate, and rib malformations. [Definition Source: NCI]
broader transitive: Disease or Disorder

Radius Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034628
comment: Traumatic or pathological injury to the radius bone in which the continuity of the bone is broken. [Definition Source: NCI]
broader transitive: Injury

Tibia Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040185
comment: Traumatic or pathological injury to the tibia in which the continuity of the bone is broken. [Definition Source: NCI]
broader transitive: Injury

Autoimmune Nervous System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0751871
comment: A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis. [Definition Source: NCI]
broader transitive: Autoimmune Disease

Adverse Drug Event
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
comment: An adverse event that occurs after a drug administration. [Definition Source: OAE]

Administration of Ineffective Drug
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0852908
comment: An errored drug administration where a patient is administered with an ineffective drug. [Definition Source: OAE]
broader transitive: Adverse Drug Event

Drug Hypersensitivity AE
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013182
comment: A hypersensitivity AE that has an outcome of allergic reactions to certain drugs. [Definition Source: OAE]
broader transitive: Adverse Drug Event

Drug Intolerance AE
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0277585
comment: A drug AE that has an outcome of lower threshold to the normal pharmacologic action of a drug. [Definition Source: OAE]
broader transitive: Adverse Drug Event

Institute of Molecular Medicine Joao Lobo Antunes
type: NamedIndividual
type: Clinics and Hospitals
label: Instituto de medicina molecular Joao Lobo Antunes @pt

Nicola Ferro
type: NamedIndividual
type: Person

Giorgio Maria Di Nunzio
type: NamedIndividual
type: Person

Laura Menotti
type: NamedIndividual
type: Person

Guglielmo Faggioli
type: NamedIndividual
type: Person

Stefano Marchesin
type: NamedIndividual
type: Person

Gianmaria Silvello
type: NamedIndividual
type: Person

Behavioral Impairment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
comment: Diminished psychological function.
broader transitive: Finding

Cortisone Therapy for Relapse
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Therapy based on cortisone used for treating relapses.

Drugs for MS Symptomatic Therapy
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Symptomatic therapy for Multiple Sclerosis (MS).

Drugs for MS Therapy Side Effects
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Therapy for managing side effects of MS therapy.

Drugs for Other Diseases
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Any drugs used to treat other diseases.

Immunoactive Drugs
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
comment: Therapy employed to slow the progression of the disease.

Covid-19 Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5400806
broader transitive: Other Vaccines

BG-12
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: Dimethyl Fumarate
broader transitive: Other Nervous System Drugs

Ecunerv
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
comment: Ecunerv is recommended to help maintain normal functions of the nervous system under abnormal conditions such as neuropathy (due to mechanical, metabolic, toxic, ischemic, optical, alcoholic, diabetic or post-herpetic causes), canalicular syndrome, radiculopathy. B-vitamins (B1, B6 and B12) work in synergy with magnesium and help maintain normal functions of the nervous system. Vitamin E helps protect cells from oxidative stress. [Definition Source: https://www.ecupharma.it/en/ecunerv - visited on November 28th, 2022]
broader transitive: Dietary Supplement
note: Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30.

Hospital General Universitario Gregorio Marañón
type: NamedIndividual
type: Clinics and Hospitals

Mondino Foundation
type: NamedIndividual
type: Clinics and Hospitals

University of Padua
type: NamedIndividual
type: Clinics and Hospitals
label: Università degli Studi di Padova @it

University of Turin
type: NamedIndividual
type: Clinics and Hospitals
label: Università degli Studi di Torino @it

Nitrogen Dioxide concentration

Ozone concentration

Particulate Matter <10 µm concentration

Particulate Matter <2.5 µm concentration

Sulphur Dioxide concentration