Secondary use of clinical trials data in health research: A Practical Guide

This document presents a theoretical framework for the use of clinical trials and other health data for secondary research purposes, which was derived from research papers, consultation with stakeholders and the research community.  Four overall scenarios for data reuse were identified; scenario 1: evidence synthesis, scenario 2: secondary analyses, scenario 3: reproducibility, replication and validation, and scenario 4: education and methods development.