Published March 12, 2018 | Version v1
Poster Open

OpenRiskNet, an open e-infrastructure to support data sharing, knowledge integration and in silico analysis and modelling in risk assessment

  • 1. Douglas Connect, Switzerland
  • 2. Universiteit Maastricht, Netherlands
  • 3. Fraunhofer Gesellschaft Zur Foerderung Der Angewandten Forschung E.V., Germany
  • 4. National Technical University Of Athens, Greece
  • 5. The University Of Birmingham, United Kingdom
  • 6. Johannes Gutenberg-Universitat Mainz, Germany
  • 7. Fundacio Centre De Regulacio Genomica, Spain
  • 8. Uppsala Universitet, Sweden
  • 9. Vrije Universiteit Amsterdam, Netherlands
  • 10. Informatics Matters Limited, United Kingdom
  • 11. Institut National De L'environnement Et Des Risques INERIS, France


OpenRiskNet ( is an EU funded infrastructure project with the main objective to develop an open e-infrastructure providing resources and services to a variety of industries requiring risk assessment, including chemicals, cosmetic ingredients, drugs and nanomaterials.

The OpenRiskNet approach is to work on different case studies to test and evaluate requirements to overcome the fragmentation of data and tools and to provide solutions improving the harmonization of data, usability and interoperability of application programming interfaces (APIs) and the deployment into virtual infrastructure. The cases present real-world settings such as systems biology approaches for grouping compounds, read-across applications using chemical and biological similarity, and identifying areas of concern based only on alternative methods approaches.

We discuss our progress on the OpenRiskNet goal of harmonizing data and metadata within APIs that can be added to already existing analysis and modeling services and data warehouses. We also demonstrate how these APIs can easily be used towards the generation of full risk assessment workflows either using scripting languages or workflow managers. Finally, we show the first approaches to make these APIs semantically rich by annotating data with human- and computer-readable data schemata.

OpenRiskNet has initiated the Associated Partners Programme strengthening the working ties between the OpenRiskNet members and other organizations within the scientific community.



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OpenRiskNet – OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment 731075
European Commission