,EffectNumber,EffectNote,StudyID,Author,Year,Title,Species,AdversityMeasure,AdversityOrEnrichmentType,AdversitySubCategory,SubCategory2,AgeAtAdversity,AveAgeAdversity,AgeAtMaturity,Lifestage,MaxLifespan,LengthExposure,Population,Overlaps,OverlapStudyID,ProblematicOverlap,AgeAtFirstTL,AgeAtLastTL,LifestageAtLastTL,SameLifestage,LifestageAtStressVSMeasurement,Females,Males,Sex,n,Tissue,TissueType,Technique,Experimental,Longitudinal,InduceOrReduce,ReportedSignificant,PredictedDirection,IV,DV,ReportedDirection,Adjusted,Effect,EffectConcordant,F,df2F,t,dft,d,MeanStressed,MeanUnstressed,SEStressed,SEUnstressed,SDStressed,SDUnstressed,nStressed,nUnstressed,r,B,uB,SDIV,SDDV,Notes,CommonEffect,CommonEffectVariance
1,652,m,adaikalakoteswari2005,adaikalakoteswari,2005,Telomere shortening occurs in Asian Indian Type 2 diabetic patients,homo sapiens,Type 2 diabetes,disease,diabetes,none,49 years ± 7.5,17885,4927.5,adult,44712.5,1204.5,Diabetic subjects and controls from Chennai Urban Rural Epidemiological Study (CURES),0,NA,0,NA,17885,adult,1,adultadult,40,40,both,80,wholeblood,wbcs,southernblot,0,0,NA,1,negative,Type 2 diabetes vs. control,Mean TRF in kb,negative,0,meansse,1,NA,NA,NA,NA,-1.096015511,6.01,9.11,0.2,0.6,1.264911064,3.794733192,40,40,NA,NA,NA,NA,NA,,-0.480576838,0.007486476
2,653,m,adaikalakoteswari2007,adaikalakoteswari,2007,Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy,homo sapiens,Diabetic status (type 2) without atherosclerosis,disease,diabetes,none,Mean age = 49 years,17885,4927.5,adult,44712.5,1095,"Subjects with impaired glucose tolerance (IGT) (n = 30), non-diabetic control subjects (n = 30), Type 2 diabetic patients without (n = 30) and with atherosclerotic plaques (n = 30) from the Chennai Urban Rural Epidemiology Study (CURES).",1,monickaraj2012,1,NA,17885,adult,1,adultadult,unreported,unreported,both,60,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Diabetics.Controls,LTL mTRF,negative,1,meansse,1,NA,NA,NA,NA,-1.193863621,6.21,8.7,0.2,0.5,1.095445115,2.738612788,30,30,NA,NA,NA,NA,NA,,-0.512557303,0.009213376
3,654,m,adaikalakoteswari2007,adaikalakoteswari,2007,Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy,homo sapiens,Impaired glucose tolerance,disease,diabetes,none,Mean age = 48 years,17520,4927.5,adult,44712.5,NA,"Subjects with impaired glucose tolerance (IGT) (n = 30), non-diabetic control subjects (n = 30), Type 2 diabetic patients without (n = 30) and with atherosclerotic plaques (n = 30) from the Chennai Urban Rural Epidemiology Study (CURES).",1,monickaraj2012,1,NA,17520,adult,1,adultadult,unreported,unreported,both,60,leukocytes,wbcs,southernblot,0,0,NA,1,negative,GlucoseIntolerant.Controls,LTL mTRF,negative,1,meansse,1,NA,NA,NA,NA,-0.766056876,6.97,8.7,0.3,0.5,1.643167673,2.738612788,30,30,NA,NA,NA,NA,NA,,-0.357687753,0.012889622
4,655,m,adaikalakoteswari2007,adaikalakoteswari,2007,Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy,homo sapiens,Diabetic & atherosclerotic status,disease,diabetes,none,Mean age = 56,20440,4927.5,adult,44712.5,4745,"Subjects with impaired glucose tolerance (IGT) (n = 30), non-diabetic control subjects (n = 30), Type 2 diabetic patients without (n = 30) and with atherosclerotic plaques (n = 30) from the Chennai Urban Rural Epidemiology Study (CURES).",1,monickaraj2012,1,NA,20440,adult,1,adultadult,unreported,unreported,both,60,leukocytes,wbcs,southernblot,0,0,NA,1,negative,DiabeticAtherosclerotics.Controls,LTL mTRF,negative,1,meansse,1,NA,NA,NA,NA,-1.587023528,5.39,8.7,0.2,0.5,1.095445115,2.738612788,30,30,NA,NA,NA,NA,NA,,-0.621591038,0.006381951
5,303,m,adler2013,adler,2013,"Educational attainment and late life telomere length in the Health, Aging and Body Composition Study",homo sapiens,Education greater than high school,socioeconomic,education,higher,Mean age = 73.55,26845.75,4927.5,adult,44712.5,unreported,"Health, Aging & Body Composition (Health ABC) Study participants aged 70–79 in Pittsburgh, PA & Memphis, TN",0,NA,0,NA,26845.75,adult,1,adultadult,1341,1258,both,2599,leukocytes,wbcs,qpcr,0,0,NA,1,positive,EducationGreaterThanHighSchool.HighSchoolOrLess,LTL bp,positive,1,dbeta,1,NA,NA,NA,NA,0.092387288,NA,NA,NA,NA,NA,NA,1363,1236,NA,NA,125,NA,1353,,0.04608943,0.000383278
6,304,m,adler2013,adler,2013,"Educational attainment and late life telomere length in the Health, Aging and Body Composition Study",homo sapiens,Exercise (kcal/kg per week),physicalactivity,more activity,none,Mean age = 73.55,26845.75,4927.5,adult,44712.5,unreported,"Health, Aging & Body Composition (Health ABC) Study participants aged 70–79 in Pittsburgh, PA & Memphis, TN",0,NA,0,NA,26845.75,adult,1,adultadult,1341,1258,both,2599,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Exercise (kcal/kg per week),LTL bp,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.005129342,-0.1,69.4,1353,,-0.005129342,0.000384891
7,305,m,adler2013,adler,2013,"Educational attainment and late life telomere length in the Health, Aging and Body Composition Study",homo sapiens,Smoking,smoking,none,none,Mean age = 73.55,26845.75,4927.5,adult,44712.5,unreported,"Health, Aging & Body Composition (Health ABC) Study participants aged 70–79 in Pittsburgh, PA & Memphis, TN",0,NA,0,NA,26845.75,adult,1,adultadult,1341,1258,both,2599,leukocytes,wbcs,qpcr,0,0,NA,1,negative,EverSmokers.NeverSmokers,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.097191426,NA,NA,NA,NA,NA,NA,1468,1131,NA,NA,-131.5,NA,1353,,-0.048129618,0.00038313
8,306,m,adler2013,adler,2013,"Educational attainment and late life telomere length in the Health, Aging and Body Composition Study",homo sapiens,Income > 25k,socioeconomic,income,higher,Mean age = 73.55,26845.75,4927.5,adult,44712.5,unreported,"Health, Aging & Body Composition (Health ABC) Study participants aged 70–79 in Pittsburgh, PA & Memphis, TN",0,NA,0,NA,26845.75,adult,1,adultadult,1341,1258,both,2599,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Income>25k.LessIncome,LTL bp,positive,1,dbeta,1,NA,NA,NA,NA,0.063414634,NA,NA,NA,NA,NA,NA,1352,1247,NA,NA,85.8,NA,1353,,0.031665543,0.00038414
9,722,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Unmarried vs. married,psychosocial,social network,more adversity,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2911,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Unmarried vs. married,Leucocyte T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.003706883,NA,NA,NA,NA,NA,NA,639,2272,NA,NA,-0.001,NA,0.269768419,,-0.001534337,0.000343641
10,723,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,SES: Lower non-manual occupational grade vs. manual,socioeconomic,occupation or employment status,higher,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,1647,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Lower non-manual occupational grade vs. manual,Leucocyte T/S ratio,positive,1,dbeta,1,NA,NA,NA,NA,0.003706883,NA,NA,NA,NA,NA,NA,813,834,NA,NA,0.001,NA,0.269768419,,0.001853288,0.000607529
11,724,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,SES: Upper non-manual occupational grade vs. manual,socioeconomic,occupation or employment status,higher,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,1653,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Upper non-manual occupational grade vs. manual,Leucocyte T/S ratio,positive,1,dbeta,1,NA,NA,NA,NA,0.003706883,NA,NA,NA,NA,NA,NA,819,834,NA,NA,0.001,NA,0.269768419,,0.001853362,0.000605323
12,725,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Smoking: Daily smoking yes vs. no,smoking,none,none,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2911,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Daily smoking yes vs. no,Leucocyte T/S ratio,positive,1,dbeta,1,NA,NA,NA,NA,0.018534416,NA,NA,NA,NA,NA,NA,725,2186,NA,NA,0.005,NA,0.269768419,,0.008015245,0.000343598
13,726,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Somatic illness vs. none,disease,other,none,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2911,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Somatic illness vs. none,Leucocyte T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.011120649,NA,NA,NA,NA,NA,NA,1638,1273,NA,NA,-0.003,NA,0.269768419,,-0.005516359,0.000343622
14,727,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Mental illness vs. none,psychiatric,other,none,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2911,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Mental illness vs. none,Leucocyte T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.033361948,NA,NA,NA,NA,NA,NA,380,2531,NA,NA,-0.009,NA,0.269768419,,-0.011238792,0.000343556
15,728,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Work-related exhaustion mild vs. no,psychosocial,work-related stress,more adversity,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2759,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Work-related exhaustion mild vs. no,Leucocyte T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.007413766,NA,NA,NA,NA,NA,NA,530,2229,NA,NA,-0.002,NA,0.269768419,,-0.002920642,0.000362575
16,729,m,ahola2012,ahola,2012,Work-related exhaustion and telomere length: A population-based study,homo sapiens,Work-related exhaustion severe vs. no,psychosocial,work-related stress,more adversity,44.8 years,16352,4927.5,adult,44712.5,unreported,Health 2000 study (Finland),0,NA,0,NA,16352,adult,1,adultadult,1445,1466,both,2381,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Work-related exhaustion severe vs. no,Leucocyte T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.159395974,NA,NA,NA,NA,NA,NA,152,2229,NA,NA,-0.043,NA,0.269768419,,-0.038937253,0.000418895
17,437,m,asok2013,asok,2013,Parental responsiveness moderates the association between early-life stress and reduced telomere length,homo sapiens,Risk of maltreatment (high vs low) in children,parentalcare,less parental care,none,Mean age = 4.9,1788.5,4927.5,child,44712.5,unreported,89 high-risk children (+ 38 low-risk comparison children) from a longitudinal study examining the efficacy of an attachment-based intervention for infants involved in the Child Welfare System.,0,NA,0,NA,1788.5,child,1,childchild,40,49,both,89,buccal,buccal,qpcr,0,0,NA,1,negative,HighRiskChildren.LowRiskChildren,Buccal cell telomere length (T/S ratio),negative,1,fanova,1,4.37,83,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Telomere length was shorter in high-risk children compared to low-risk children.,0.223645184,0.010255311
18,438,m,asok2013,asok,2013,Parental responsiveness moderates the association between early-life stress and reduced telomere length,homo sapiens,Parental responsiveness during play task (high-risk children),parentalcare,more parental care,none,Mean age = 4.9,1788.5,4927.5,child,44712.5,unreported,89 high-risk children (+ 38 low-risk comparison children) from a longitudinal study examining the efficacy of an attachment-based intervention for infants involved in the Child Welfare System.,0,NA,0,NA,1788.5,child,1,childchild,18,33,both,51,buccal,buccal,qpcr,0,0,NA,1,positive,Parental responsiveness,Buccal cell telomere length (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.35,NA,NA,NA,NA,,0.35,0.015400125
19,439,m,asok2013,asok,2013,Parental responsiveness moderates the association between early-life stress and reduced telomere length,homo sapiens,Parental responsiveness during play task (low-risk children),parentalcare,more parental care,none,Mean age = 4.9,1788.5,4927.5,child,44712.5,unreported,89 high-risk children (+ 38 low-risk comparison children) from a longitudinal study examining the efficacy of an attachment-based intervention for infants involved in the Child Welfare System.,0,NA,0,NA,1788.5,child,1,childchild,22,16,both,38,buccal,buccal,qpcr,0,0,NA,0,positive,Parental responsiveness,Buccal cell telomere length (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.1,NA,NA,NA,NA,,-0.1,0.026489189
20,533,m,aulinas2014,aulinas,2014,Telomere length analysis in Cushing's syndrome,homo sapiens,Cushing's syndrome,disease,other,none,48.5 years,17702.5,4927.5,adult,44712.5,unreported,Cushing's syndrome patients and controls from Catalunya,0,NA,0,NA,17702.5,adult,1,adultadult,unreported,unreported,both,154,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Cushing's syndrome,Mean TL in bp,positive,0,meanssd,1,NA,NA,NA,NA,0.148721263,7667,7483,NA,NA,1260,1214,77,77,NA,NA,NA,NA,NA,,0.074155892,0.006464262
21,650,m,barcelo2010,barcelo,2010,Telomere shortening in sleep apnea syndrome,homo sapiens,Obstructive sleep apnea syndrome,disease,sleep apnea,none,Around 49 years,17885,4927.5,adult,44712.5,unreported,Patients with obstructive sleep apnea syndrome and controls from Mallorca,0,NA,0,NA,17885,adult,1,adultadult,85,319,both,404,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Obstructive sleep apnea syndrome vs. control,T/S ratio,negative,0,meansse,1,NA,NA,NA,NA,-0.023484062,0.953,0.985,0.099,0.07,1.584,0.851586754,256,148,NA,NA,NA,NA,NA,,-0.011313966,0.002480754
22,383,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,n-3 fatty acids supplementation in chronic kidney disease patients,nutrition,fats and oils,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,34,neutrophils,wbcs,qpcr,1,0,reduce,0,positive,FattyAcidIntervention.Controls,Neutrophil telomere length (kb/genome),negative,0,meansse,1,NA,NA,NA,NA,0.134106174,166.9,160.9,11.5,10.3,44.53930848,44.89665912,15,19,NA,NA,NA,NA,NA,,0.066440303,0.030036087
23,384,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,Coenzyme Q10 supplementation in chronic kidney disease patients,nutrition,other,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,36,neutrophils,wbcs,qpcr,1,0,reduce,0,positive,CoQ10Intervention.Controls,Neutrophil telomere length (kb/genome),negative,0,meansse,1,NA,NA,NA,NA,0.252472856,166.9,155.6,11.5,9.8,44.53930848,44.90924181,15,21,NA,NA,NA,NA,NA,,0.123517646,0.027706273
24,385,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,n-3 fatty acid + coenzyme Q10 supplementation in chronic kidney disease patients,nutrition,other,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,33,neutrophils,wbcs,qpcr,1,0,reduce,0,positive,FattyAcid+COQ10Intervention.Controls,Neutrophil telomere length (kb/genome),positive,0,meansse,1,NA,NA,NA,NA,-0.399757877,166.9,184.8,11.5,10.6,44.53930848,44.97199128,15,18,NA,NA,NA,NA,NA,,-0.195221374,0.028913428
25,386,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,n-3 fatty acids supplementation in chronic kidney disease patients,nutrition,fats and oils,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,34,pbmcs,wbcs,qpcr,1,0,reduce,0,positive,FattyAcidIntervention.Controls,PBMC telomere length (kb/genome),negative,0,meansse,1,NA,NA,NA,NA,0.116421809,107.1,101.9,11.6,10.2,44.92660682,44.46076922,15,19,NA,NA,NA,NA,NA,,0.057710315,0.030101519
26,387,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,Coenzyme Q10 supplementation in chronic kidney disease patients,nutrition,other,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,36,pbmcs,wbcs,qpcr,1,0,reduce,0,positive,CoQ10Intervention.Controls,PBMC telomere length (kb/genome),negative,0,meansse,1,NA,NA,NA,NA,0.237415615,107.1,96.5,11.6,9.7,44.92660682,44.45098424,15,21,NA,NA,NA,NA,NA,,0.11625384,0.027804364
27,388,m,barden2016,barden,2016,n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease,homo sapiens,n-3 fatty acid + coenzyme Q10 supplementation in chronic kidney disease patients,nutrition,other,none,Mean age = 56.5,20622.5,4927.5,adult,44712.5,56,74 men and women aged 25–75 years with chronic renal impairment,0,NA,0,NA,20678.5,adult,1,adultadult,unreported,unreported,both,33,pbmcs,wbcs,qpcr,1,0,reduce,0,positive,FattyAcid+COQ10Intervention.Controls,PBMC telomere length (kb/genome),positive,0,meansse,1,NA,NA,NA,NA,-0.004472349,107.1,107.3,11.6,10.5,44.92660682,44.54772721,15,18,NA,NA,NA,NA,NA,,-0.002226909,0.03124969
28,389,m,bassig2014,bassig,2014,Alterations in leukocyte telomere length in workers occupationally exposed to Benzene,homo sapiens,Benzene exposure levels,environmentalhazard,none,none,Mean = 35.5 years,12957.5,4927.5,adult,44712.5,unreported,"43 workers exposed to high levels of benzene and 43 age and sex-matched unexposed workers in Shanghai, China.",0,NA,0,NA,12957.5,adult,1,adultadult,42,44,both,86,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Benzene exposure (exposed vs unexposed),PBMC T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.323263475,1.32,1.26,NA,NA,0.2,0.17,43,43,NA,NA,NA,NA,NA,,0.159560925,0.01117328
29,654,sg653,bassig2014,bassig,2014,Alterations in leukocyte telomere length in workers occupationally exposed to Benzene,homo sapiens,Benzene exposure levels,environmentalhazard,none,none,Mean = 35 years,12775,4927.5,adult,44712.5,unreported,"43 workers exposed to high levels of benzene and 43 age and sex-matched unexposed workers in Shanghai, China.",0,NA,0,NA,13264.1,adult,1,adultadult,29,35,both,64,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Benzene exposure (unexposed vs <31ppm),PBMC T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.059937774,1.25,1.26,NA,NA,0.16,0.17,21,43,NA,NA,NA,NA,NA,,-0.028131481,0.015847903
30,655,sg653,bassig2014,bassig,2014,Alterations in leukocyte telomere length in workers occupationally exposed to Benzene,homo sapiens,Benzene exposure levels,environmentalhazard,none,none,Mean = 36 years,13140,4927.5,adult,44712.5,unreported,"43 workers exposed to high levels of benzene and 43 age and sex-matched unexposed workers in Shanghai, China.",0,NA,0,NA,13140,adult,1,adultadult,34,31,both,65,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Benzene exposure (unexposed vs >31ppm),PBMC T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.572637127,1.37,1.26,NA,NA,0.23,0.17,22,43,NA,NA,NA,NA,NA,,0.261533041,0.013560616
31,429,m,bateson2015,bateson,2015,Opposite Effects of Early-Life Competition and Developmental Telomere Attrition on Cognitive Biases in Juvenile European Starlings,sturnus vulgaris,Number of heavier chicks in nest on day 15 post-hatch (experimentally manipulated),socioeconomic,relative status,,15 days,15,365,juvenile,8358.5,13,"31 European starlings (15 males and 16 females) from a cohort of chicks hatched in the wild (in nest boxes located on five farms in Northumberland, UK: approximately 55°N 2°W) in May 2012.",0,NA,NA,4,55,juvenile,1,juvenilejuvenile,unreported,unreported,both,22,rbcs,rbcs,qpcr,1,1,induce,1,negative,NumberHeavierCompetitors,Erythrocyte telomere attrition (Verhulst D),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.47,NA,NA,NA,NA,,-0.47,0.02890461
32,432,m,beaulieu2011,beaulieu,2011,Oxidative status and telomere length in a long-lived bird facing a costly reproductive event,pygoscelis adeliae,Experimental manipulation of parenting effort by adding weight to increase foraging effort during breeding season,socioeconomic,income,,unreported,unreported,unavailable,unreported,unavailable,121.7,"46 pairs of Adelie penguins in Dumont d’Urville, Adelie Land, Antarctica during austral summers 2006–2007 and 2007–2008.",0,NA,NA,unreported,unreported,unreported,1,unreportedunreported,unreported,unreported,both,51,rbcs,rbcs,qpcr,1,1,induce,0,positive,HandicappedParents.Controls,Erythrocyte telomere attrition (T/S ratio),positive,0,meansse,1,NA,NA,NA,NA,0.107098261,0.033,-0.007,0.076,0.072,0.38,0.367129405,25,26,NA,NA,NA,NA,NA,"Group sizes were not reported for the attrition measure so we followed our rule that, where group sizes are not reported, assume equal group sizes or, where n is odd, allocate (n/2)+1 to the unstressed group.",0.053462268,0.019885835
33,433,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,Global severity index (PTSD),psychiatric,PTSD,none,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Global severity index (PTSD),PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.24,NA,NA,NA,NA,,-0.24,0.01184157
34,434,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,BDI,psychiatric,depression and anxiety,depression,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,BDI-II,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.079,NA,NA,NA,NA,,-0.079,0.013167426
35,435,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,CAPS lifetime,psychiatric,PTSD,none,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,ClinicianAdministeredPTSDScale,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.073,NA,NA,NA,NA,,-0.073,0.013191605
36,436,ss52,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,CAPs current,psychiatric,PTSD,none,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,ClinicianAdministeredPTSDScale,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.072,NA,NA,NA,NA,,-0.072,0.013195452
37,437,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,MDD diagnosis,psychiatric,depression and anxiety,depression,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,MDD diagnosis,PBMC T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.049,NA,NA,NA,NA,,0.049,0.013269384
38,438,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,PTSD diagnosis,psychiatric,PTSD,none,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,PTSD diagnosis,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.076,NA,NA,NA,NA,,-0.076,0.013179751
39,439,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,Early trauma inventory ,psychosocial,traumatic experience,more adversity,unreported,unreported,"5,110",child,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,0,childadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Early trauma inventory ,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.428,NA,NA,NA,NA,,-0.428,0.008895845
40,440,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,Perceived stress scale,psychosocial,stress,more adversity,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived stress scale,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.277,NA,NA,NA,NA,,-0.277,0.011365725
41,441,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,PANAS positive,psychosocial,mood,less adversity,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,1,positive,PANAS positive subscale,PBMC T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.263,NA,NA,NA,NA,,0.263,0.011552618
42,442,m,bersani2016,bersani,2016,Association of dimensional psychological health measures with telomere length in male war veterans,homo sapiens,PANAS negative,psychosocial,mood,more adversity,Mean age = 34.64,12643.6,"5,110",adult,44712.5,unreported,"76 combat-exposed male veterans (41 psychiatrically healthy, 18 with Posttraumatic Stress Disorder [PTSD] and 17 with concomitant PTSD and Major Depressive Disorder [MDD]",0,NA,0,NA,12643.6,adult,1,adultadult,0,76,male,76,pbmcs,wbcs,qpcr,0,0,NA,0,negative,PANAS negative subscale,PBMC T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.14,NA,NA,NA,NA,,-0.14,0.012815789
43,370,m,boccardi2013,boccardi,2013,"Mediterranean Diet, Telomere Maintenance and Health Status among Elderly",homo sapiens,Current smoking (never vs current),smoking,none,none,Mean age = 77.9,28433.5,4927.5,adult,44712.5,unreported,"Caucasians subjects living in Campania, Southern Italy.",0,NA,0,NA,28433.5,adult,1,adultadult,102,115,both,159,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smokers.Non-smokers,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.824805293,4.49,4.98,NA,NA,0.53,0.61,34,125,NA,NA,NA,NA,NA,,-0.320357445,0.005096677
44,371,m,boccardi2013,boccardi,2013,"Mediterranean Diet, Telomere Maintenance and Health Status among Elderly",homo sapiens,Ever smoking (never vs former),smoking,none,none,Mean age = 77.9,28433.5,4927.5,adult,44712.5,unreported,"Caucasians subjects living in Campania, Southern Italy.",0,NA,0,NA,28433.5,adult,1,adultadult,102,115,both,183,leukocytes,wbcs,qpcr,0,0,NA,1,negative,EverSmokers.NeverSmokers,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.101892809,4.92,4.98,NA,NA,0.54,0.61,58,125,NA,NA,NA,NA,NA,,-0.047355882,0.005469889
45,730,m,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,Smoking (pack-years),smoking,none,none,46.8 years,17082,"5,110",adult,44712.5,NA,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking (pack-years),LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.05,NA,NA,NA,NA,,-0.05,0.006218789
46,731,m,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,"Depression (Center for Epidemiologic Studies–Depression, CESD, score)",psychiatric,depression and anxiety,depression,46.8 years,17082,"5,110",adult,44712.5,unreported,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Depression (CESD score),LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.09,NA,NA,NA,NA,,0.09,0.00614916
47,732,m,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,Total sleep time ,sleep,more sleep,none,46.8 years,17082,"5,110",adult,44712.5,unreported,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Total sleep,LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.07,NA,NA,NA,NA,,0.07,0.0061889
48,733,ss732,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,Slow-wave sleep minutes,sleep,more sleep,none,46.8 years,17082,"5,110",adult,44712.5,unreported,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Slow-wave sleep,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.02,NA,NA,NA,NA,,-0.02,0.006245001
49,734,ss732,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,REM sleep minutes,sleep,more sleep,none,46.8 years,17082,"5,110",adult,44712.5,unreported,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,0,positive,REM sleep,LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.1,NA,NA,NA,NA,,0.1,0.006125625
50,735,m,boyer2016,boyer,2016,Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing,homo sapiens,Severity of sleep apnea (Apnea–hypopnea index (AHI) events per hour),disease,sleep apnea,none,46.8 years,17082,"5,110",adult,44712.5,unreported,"161 prospectivelly enrolled, untreated, middle-aged men free of known comorbidities related or unrelated to sleep apnea.",0,NA,0,NA,17082,adult,1,adultadult,0,161,male,161,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Sleep apnea index,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.17,NA,NA,NA,NA,,-0.17,0.00589397
51,449,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,"Family socioeconomic risk (at age 17) - indexed by: family poverty based on federal guidelines, primary caregiver unemployment, receipt of Temporary Assistance for Needy Families, primary caregiver single parenthood, primary caregiver education level less than high school graduation, and caregiver-reported inadequacy of family income.",socioeconomic,composite measure,lower,Mean age = 17.7,6460.5,4927.5,adult,44712.5,unreported,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Family Socioeconomic Risk,Lymphocyte TL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.003,NA,NA,NA,,-0.003,0.004651079
52,450,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,"Life stress (at age 17) based on checklist of 12 events e.g., acute economic stress, death of a friend, parental divorce, serious injury or illness",psychosocial,stress,more adversity,Mean age = 17.7,6460.5,4927.5,adult,44712.5,unreported,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Life stress,Lymphocyte TL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.056,NA,NA,NA,,-0.056,0.004622036
53,451,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,Smoking (at age 17) - 7-point response set ranging from not at all to about two packs a day,smoking,none,none,Mean age = 17.7,6460.5,4927.5,adult,44712.5,unreported,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking,Lymphocyte TL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.006,NA,NA,NA,,0.056,0.004622036
54,452,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,Alcohol use (at age 17) - 6-point scale ranging from none to 20 or more days,alcohol,more alcohol,none,Mean age = 17.7,6460.5,4927.5,adult,44712.5,unreported,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Alcohol use,Lymphocyte TL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.002,NA,NA,NA,,0.052,0.004626043
55,453,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,"Nonsupportive parenting (at age 17) - measured using two scales completed by parents: 1) the ineffective arguing inventory (IAI), 2) a 4-item arguing subscale from the discussion quality scale (DQS)",parentalcare,less parental care,none,Mean age = 17.7,6460.5,4927.5,adult,44712.5,unreported,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,0,0,NA,1,negative,Nonsupportive parenting,Lymphocyte TL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.139,NA,NA,NA,,-0.139,0.004473169
56,454,m,brody2015,brody,2015,Prevention Effects Ameliorate the Prospective Association Between Nonsupportive Parenting and Diminished Telomere Length,homo sapiens,Effect of parental/family training intervention (6 weeks at age 17),parentalcare,more parental care,none,Mean age = 17.7,6460.5,4927.5,adult,44712.5,42,216 participants in the AIM (Adults in the Making) trial were African American Youths in a trial of a parenting intervention. ,0,NA,0,NA,8030,adult,1,adultadult,unclear,unclear,both,216,lymphocytes,wbcs,qpcr,1,0,reduce,0,positive,ParentingIntervention.Controls,Lymphocyte TL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.114,NA,NA,NA,"There was a significant interaction of the intervention with nonsupportive parenting, but it could not be extracted.",0.164,0.004404332
57,318,m,brydon2012,brydon,2012,Hostility and Cellular Aging in Men from the Whitehall II Cohort,homo sapiens,Smoking,smoking,none,none,Mean = 63.3,23104.5,4927.5,adult,44712.5,unreported,434 men and women from the Whitehall II cohort,0,NA,0,NA,23104.5,adult,1,adultadult,228,206,both,434,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Smoking status,PBMC T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.09,NA,NA,NA,NA,,-0.09,0.002272207
58,375,m,cai2015,cai,2015,Molecular Signatures of Major Depression,homo sapiens,Major depression,psychiatric,depression and anxiety,depression,unreported,unreported,"4,745",unreported,44712.5,unreported,"11,670 women from China, Oxford and VCU Experimental Research on Genetic Epidemiology (CONVERGE)",0,NA,0,NA,unreported,unreported,1,unreportedunreported,"11,670",0,female,11670,wholegenome,wbcs,telseq,0,0,NA,1,negative,Major depressive status,Normalised TL from whole genome,negative,1,fanova,1,62.38,10685,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.076185335,8.47E-05
59,376,m,cai2015,cai,2015,Molecular Signatures of Major Depression,homo sapiens,Stressful Life Events,psychosocial,stress,more adversity,unreported,unreported,"4,745",unreported,44712.5,unreported,"11,670 women from China, Oxford and VCU Experimental Research on Genetic Epidemiology (CONVERGE)",0,NA,0,NA,unreported,unreported,1,unreportedunreported,"11,670",0,female,11670,wholegenome,wbcs,telseq,0,0,NA,1,negative,Stressful Life Events,Normalised TL from whole genome,negative,1,fanova,1,9.91,10685,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.030440253,8.55E-05
60,377,m,cai2015,cai,2015,Molecular Signatures of Major Depression,homo sapiens,"Childhood Sexual Abuse (none vs non-genital, genital & intercourse CSA)",psychosocial,traumatic experience,more adversity,unreported,unreported,"4,745",child,44712.5,unreported,"11,670 women from China, Oxford and VCU Experimental Research on Genetic Epidemiology (CONVERGE)",0,NA,0,NA,unreported,unreported,0,childunreported,"11,670",0,female,11670,wholegenome,wbcs,telseq,0,0,NA,1,negative,Childhood Sexual Abuse,Normalised TL from whole genome,negative,1,fanova,1,4.18,11273,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.019252533,8.56E-05
61,307,m,cardin2013a,cardin,2013a,Effects of coffee consumption in chronic hepatitis C: A randomized controlled trial,homo sapiens,Coffee consumption in chronic hepatitis patients (RCT - 4 cups a day for 30 days),nutrition,tea and coffee,none,Mean age = 58,21170,4927.5,adult,44712.5,30,37 patients with HCV-related chronic liver disease referred to the Gastroenterology Unit of Padua outpatient clinic were prospectively recruited for the study.,0,NA,0,NA,21200,adult,1,adultadult,8,29,both,37,wholeblood,wbcs,qpcr,1,0,reduce,1,positive,CoffeeIntervention.Controls,Wholeblood T/S ratio??,positive,0,meansse,1,NA,NA,NA,NA,-0.64482588,0.48,0.68,0.04,0.06,0.243310501,0.364965752,37,37,NA,NA,NA,NA,NA,This is an unusual comparison because it is within subjects in an RCT.,-0.306858206,0.022792849
62,430,m,cardin2013b,cardin,2013b,Oxidative DNA Damage in Barrett Mucosa: Correlation with Telomeric Dysfunction and p53 Mutation,homo sapiens,Long Barret's Oesophagus,disease,other,none,Mean age = 60,21900,4927.5,adult,44712.5,unreported,"60 consecutive prospectively recruited patients at the outpatient clinic of the Department of Surgery, Oncology, and Gastroenterology of Padua University, Padua, Italy, between 2009 and 2011 + 20 controls with long-lasting GERD symptoms undergoing endoscopy to confirm or exclude a diagnosis of Barrett esophagus, in whom endoscopy and gastroesophageal junction biopsy results excluded the presence of Barrett esophagus.",0,NA,0,NA,21900,adult,1,adultadult,unreported,unreported,both,39,oesophagus,other,qpcr,0,0,NA,0,negative,LongBarrets.Controls,Oesophageal TL (T/S ratio),positive,0,meansse,1,NA,NA,NA,NA,0.022637698,0.74,0.73,0.1,0.1,0.435889894,0.447213595,19,20,NA,NA,NA,NA,NA,,0.011314403,0.026309052
63,431,m,cardin2013b,cardin,2013b,Oxidative DNA Damage in Barrett Mucosa: Correlation with Telomeric Dysfunction and p53 Mutation,homo sapiens,Short Barret's Oesophagus,disease,other,none,Mean age = 60,21900,4927.5,adult,44712.5,unreported,"60 consecutive prospectively recruited patients at the outpatient clinic of the Department of Surgery, Oncology, and Gastroenterology of Padua University, Padua, Italy, between 2009 and 2011 + 20 controls with long-lasting GERD symptoms undergoing endoscopy to confirm or exclude a diagnosis of Barrett esophagus, in whom endoscopy and gastroesophageal junction biopsy results excluded the presence of Barrett esophagus.",0,NA,0,NA,21900,adult,1,adultadult,unreported,unreported,both,41,oesophagus,other,qpcr,0,0,NA,1,negative,ShortBarrets.Controls,Oesophageal TL (T/S ratio),negative,0,meansse,1,NA,NA,NA,NA,-0.793998104,0.45,0.73,0.05,0.1,0.229128785,0.447213595,21,20,NA,NA,NA,NA,NA,,-0.368890131,0.018658947
64,372,m,carlson2015,carlson,2015,Mindfulness-Based Cancer Recovery and Supportive-Expressive Therapy Maintain Telomere Length Relative to Controls in Distressed Breast Cancer Survivors,homo sapiens,Intervention effects (mindfulness & group therapy combined) versus control groups in cancer patients,psychosocial,other positive,less adversity,Mean age =  54.83,20012.95,"4,745",adult,44712.5,70,"88 breast cancer survivors who had completed all medical treatments at least 3 months previously, with the exception of hormonal or trastuzumab therapy.",0,NA,0,NA,20082.95,adult,1,adultadult,88,0,female,88,blood,wbcs,qpcr,1,1,reduce,0,positive,Mindfulness/GroupTherapy.Controls,? T/S ratio postintervention (adjusted for baseline),positive,1,fanova,1,3.82,84,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,"Direction of effect was trend towards decreased TL attrition in intervention groups combined. Average interevention length was 10 days as this combines groups (some with 8-week mindfullness interventions, and some with 12-week group therapy).",0.208561895,0.010516045
65,373,m,carlson2015,carlson,2015,Mindfulness-Based Cancer Recovery and Supportive-Expressive Therapy Maintain Telomere Length Relative to Controls in Distressed Breast Cancer Survivors,homo sapiens,Calgary Symptoms of Stress Inventory (C-SOSI)in cancer patients,psychosocial,stress,more adversity,Mean age =  54.83,20012.95,"4,745",adult,44712.5,754.94,"88 breast cancer survivors who had completed all medical treatments at least 3 months previously, with the exception of hormonal or trastuzumab therapy.",0,NA,0,NA,20082.95,adult,1,adultadult,88,0,female,88,blood,wbcs,qpcr,0,1,NA,0,negative,Symptoms of stress,Change in ? T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.07,NA,NA,NA,NA,Time since diagnosis was used as exposure length.,0.07,0.011381885
66,374,m,carlson2015,carlson,2015,Mindfulness-Based Cancer Recovery and Supportive-Expressive Therapy Maintain Telomere Length Relative to Controls in Distressed Breast Cancer Survivors,homo sapiens,Profile of Mood States (POMS) in cancer patients,psychosocial,mood,more adversity,Mean age =  54.83,20012.95,"4,745",adult,44712.5,754.94,"88 breast cancer survivors who had completed all medical treatments at least 3 months previously, with the exception of hormonal or trastuzumab therapy.",0,NA,0,NA,20082.95,adult,1,adultadult,88,0,female,88,blood,wbcs,qpcr,0,1,NA,0,negative,Mood disturbance,Change in ? T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.11,NA,NA,NA,NA,Time since diagnosis was used as exposure length.,-0.11,0.011217775
67,375,m,castaldo2013,castaldo,2013,Can telomere shortening in human peripheral blood leukocytes serve as a disease biomarker of Friedreich's Ataxia?,homo sapiens,Friedreich’s ataxia duration,disease,other,none,15.9-30.6 years (mean age at onset to mean age at study),8486.25,4927.5,adult,44712.5,NA,37 patients with Friedreich’s ataxia and 36 controls,0,NA,0,NA,12118,adult,1,adultadult,18,19,both,37,leukocytes,wbcs,qpcr,0,1,NA,1,negative,Duration of Friedreich’s Ataxia,LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.594,NA,NA,NA,NA,,-0.594,0.011633923
68,259,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,9-item experiences of discrimination (EOD) measure,psychosocial,other negative,more adversity,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Discrimination,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.098,NA,NA,NA,NA,,-0.098,0.010778948
69,260,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,10-item centers for epidemiology studies depression scale (CES-D),psychiatric,depression and anxiety,depression,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Depression,LTL kb,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.004,NA,NA,NA,NA,,0.004,0.010988659
70,261,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,7-item anxiety subscale of the hospital anxiety and depression scale (HADS),psychiatric,depression and anxiety,anxiety,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Anxiety,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.138,NA,NA,NA,NA,,-0.138,0.010574447
71,262,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,Ratio of household income to the poverty threshold based on household composition,socioeconomic,income,higher,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Income/poverty ratio,LTL kb,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.332,NA,NA,NA,NA,,0.332,0.008700015
72,263,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,Educational attainment (high school graduate or less vs. some college or more),socioeconomic,education,lower,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Education,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.038,NA,NA,NA,NA,,-0.038,0.010957298
73,264,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,Work status (currently working or unemployed),socioeconomic,occupation or employment status,higher,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Work status,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.007,NA,NA,NA,NA,,-0.007,0.010987934
74,265,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,Smoking status (current smoking defined as smoking at least 100 cigarettes inone’s lifetime and currently smoking at least “some days”),smoking,none,none,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking status,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.106,NA,NA,NA,NA,,-0.106,0.010743453
75,266,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,"Health conditions (using a checklist of common diseases (e.g.,cardiovascular diseases, diabetes, cancer, renal disease)",disease,other,none,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Health conditions,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.029,NA,NA,NA,NA,,-0.029,0.010970535
76,267,m,chae2016,chae,2016,"Discrimination, mental health, and leukocyte telomere length among African American men",homo sapiens,Medication use (prescribed by current doctor),medicaltreatment,none,none,Mean age = 43.86,16008.9,"5,110",adult,44712.5,unreported,95 African American men from the Bay Area Heart Health Study,0,NA,0,NA,16008.9,adult,1,adultadult,0,92,male,92,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Medication use,LTL kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.279,NA,NA,NA,NA,,-0.279,0.009344805
77,138,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Education (Primary or less vs secondary or above) for men only ,socioeconomic,education,lower,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,positive,PrimaryEducationOrLess.SecondaryEducationOrAbove ,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,0.036897589,8.84,8.78,NA,NA,1.66,1.57,602,374,NA,NA,NA,NA,NA,,0.017935453,0.001024981
78,139,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Drinker status for men only,alcohol,more alcohol,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Drinkers.Non-drinkers,LTL kb,positive,0,meanssd,1,NA,NA,NA,NA,0.012303101,8.83,8.81,NA,NA,1.61,1.63,216,760,NA,NA,NA,NA,NA,,0.005107317,0.001025588
79,140,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Smoker status for men only,smoking,none,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smokers.Non-smokers,LTL kb,positive,0,meanssd,1,NA,NA,NA,NA,0.160614017,9.04,8.78,NA,NA,1.68,1.61,121,855,NA,NA,NA,NA,NA,,0.052856919,0.001019918
80,141,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Heart disease for men only,disease,cardiovascular,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,1,negative,HeartDisease.Control,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.227949842,8.48,8.85,NA,NA,1.56,1.63,98,878,NA,NA,NA,NA,NA,,-0.068349127,0.001016081
81,142,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Diabetes for men only,disease,diabetes,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Diabetes.Controls,LTL kb,positive,0,meanssd,1,NA,NA,NA,NA,0.061460027,8.9,8.8,NA,NA,1.67,1.62,137,839,NA,NA,NA,NA,NA,,0.021344463,0.001024707
82,143,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Hypertension for men only,disease,cardiovascular,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Hypertensives.Controls,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.074010057,8.74,8.86,NA,NA,1.68,1.58,397,579,NA,NA,NA,NA,NA,,-0.036331943,0.001022935
83,144,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Education (Primary or less vs secondary or above) for women only ,socioeconomic,education,lower,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,PrimaryEducationOrLess.SecondaryEducationOrAbove ,LTL kb,positive,0,meanssd,1,NA,NA,NA,NA,-0.044155098,9.33,9.43,NA,NA,2.3,2.1,841,189,NA,NA,NA,NA,NA,,-0.017088703,0.00097125
84,145,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Drinker status for women only,alcohol,more alcohol,none,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1029,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Drinkers.Non-drinkers,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.110247432,9.11,9.36,NA,NA,2.19,2.27,32,997,NA,NA,NA,NA,NA,,-0.019133577,0.000972051
85,146,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Smoker status for women only,smoking,none,none,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1030,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smokers.Non-smokers,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.00441858,9.34,9.35,NA,NA,2.8,2.25,23,1007,NA,NA,NA,NA,NA,,-0.000652866,0.000971816
86,147,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Heart disease for women only,disease,cardiovascular,none,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1030,leukocytes,wbcs,qpcr,0,0,NA,0,negative,HeartDisease.Control,LTL kb,positive,0,meanssd,1,NA,NA,NA,NA,0.053088566,9.46,9.34,NA,NA,2.16,2.27,93,937,NA,NA,NA,NA,NA,,0.015213347,0.000971368
87,148,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Diabetes for women only,disease,diabetes,none,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1030,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Diabetes.Controls,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.159188377,9.04,9.4,NA,NA,2.27,2.26,152,878,NA,NA,NA,NA,NA,,-0.056370524,0.000965651
88,149,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Hypertension for women only,disease,cardiovascular,none,72·0 years,26280,"4,745",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,female,1030,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Hypertensives.Controls,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.013248814,9.33,9.36,NA,NA,2.27,2.26,448,582,NA,NA,NA,NA,NA,,-0.006567966,0.000971733
89,150,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Cereal consumption in men only,nutrition,grains,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Cereal consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.025,NA,NA,NA,,-0.025,0.001024359
90,151,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Meat/poultry consumption in men only,nutrition,"meat, fish and eggs",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Meat/poultry consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.03,NA,NA,NA,,0.08,0.001012555
91,152,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Egg/egg product consumption in men only,nutrition,"meat, fish and eggs",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Egg/egg product consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.008,NA,NA,NA,,0.058,0.001018752
92,153,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fish consumption in men only,nutrition,"meat, fish and eggs",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Fish consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.006,NA,NA,NA,,-0.006,0.001025567
93,154,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Milk/milk product consumption in men only,nutrition,dairy,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Milk/milk product consumption ml/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.079,NA,NA,NA,,0.129,0.00099179
94,155,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fruit/dried fruit consumption in men only,nutrition,"fruit, legumes and vegetables",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Fruit/dried fruit consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.094,NA,NA,NA,,-0.094,0.001007596
95,156,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Vegetable consumption in men only,nutrition,"fruit, legumes and vegetables",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Vegetable consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.034,NA,NA,NA,,-0.034,0.001023271
96,157,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,"Legume, seed & nut consumption in men only",nutrition,"fruit, legumes and vegetables",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Legume, seed & nut consumption g/d",LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001025436
97,158,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Pickled vegetable consumption in men only,nutrition,"fruit, legumes and vegetables",none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Pickled vegetable consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.035,NA,NA,NA,,0.085,0.001010874
98,159,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Dim sum consumption in men only,nutrition,other,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Dim sum consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.066,NA,NA,NA,,0.116,0.000998225
99,160,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fast food consumption in men only,nutrition,other,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Fast food consumption log g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.011,NA,NA,NA,,-0.011,0.001025393
100,161,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fat and oil consumption in men only,nutrition,fats and oils,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,0,none,Fat and oil consumption ml/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.031,NA,NA,NA,,0.081,0.001012227
101,162,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Chinese tea consumption in men only,nutrition,tea and coffee,none,72·8 years,26572,"5,110",adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26572,adult,1,adultadult,0,976,male,976,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Chinese tea consumption ml/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.157,NA,NA,NA,,0.207,0.000939629
102,163,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Cereal consumption in women only,nutrition,grains,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Cereal consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.021,NA,NA,NA,,0.071,0.000962044
103,164,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Meat/poultry consumption in women only,nutrition,"meat, fish and eggs",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Meat/poultry consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.008,NA,NA,NA,,0.058,0.00096529
104,165,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Egg/egg product consumption in women only,nutrition,"meat, fish and eggs",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Egg/egg product consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.003,NA,NA,NA,,-0.003,0.0009718
105,166,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fish consumption in women only,nutrition,"meat, fish and eggs",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Fish consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.07,NA,NA,NA,,0.12,0.00094403
106,167,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Milk/milk product consumption in women only,nutrition,dairy,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Milk/milk product consumption ml/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.061,NA,NA,NA,,0.111,0.000948017
107,168,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fruit/dried fruit consumption in women only,nutrition,"fruit, legumes and vegetables",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Fruit/dried fruit consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.066,NA,NA,NA,,0.116,0.00094584
108,169,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Vegetable consumption in women only,nutrition,"fruit, legumes and vegetables",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Vegetable consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.017,NA,NA,NA,,0.067,0.000963112
109,170,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,"Legume, seed & nut consumption in women only",nutrition,"fruit, legumes and vegetables",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Legume, seed & nut consumption g/d",LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.072,NA,NA,NA,,0.122,0.000943104
110,171,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Pickled vegetable consumption in women only,nutrition,"fruit, legumes and vegetables",none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Pickled vegetable consumption g/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,,-0.07,0.000962317
111,172,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Dim sum consumption in women only,nutrition,other,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,none,Dim sum consumption g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.044,NA,NA,NA,,0.094,0.000954719
112,173,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fast food consumption in women only,nutrition,other,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Fast food consumption log g/d,LTL kb,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.048,NA,NA,NA,,0.098,0.00095324
113,174,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Fat and oil consumption in women only,nutrition,fats and oils,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,1,none,Fat and oil consumption ml/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.136,NA,NA,NA,,-0.136,0.0009362
114,175,m,chan2010,chan,2010,Chinese tea consumption is associated with longer telomere length in elderly Chinese men,homo sapiens,Chinese tea consumption in women only,nutrition,tea and coffee,none,72·0 years,26280,4927.5,adult,44712.5,unreported,2006 Chinese (976 men and 1030 women) aged 65 years and over,0,NA,0,NA,26280,adult,1,adultadult,1030,0,both,1030,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Chinese tea consumption ml/d,LTL kb,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.043,NA,NA,NA,,-0.043,0.000968227
115,176,m,chen2014,chen,2014,Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults,homo sapiens,Adverse Childhood Experiences scale,psychosocial,traumatic experience,more adversity,unreported,unreported,4927.5,child,44712.5,unreported,"Twenty subjects with MDD and 20 healthy controls (individually matched on age +/-3 years, gender and ethnicity) participated and completed all procedures. The individuals with MDD and 18 of the controls have been described in other publications using different measures and testing different hypotheses (Wolkowitz et al.,2012).",0,NA,0,NA,unreported,unreported,0,childunreported,unreported,unreported,both,20,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Adverse childhood experience in controls,LTL base pairs,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.61,NA,NA,NA,NA,,-0.61,0.020750443
116,177,m,chen2014,chen,2014,Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults,homo sapiens,Adverse Childhood Experiences scale,psychosocial,traumatic experience,more adversity,unreported,unreported,4927.5,child,44712.5,unreported,"Twenty subjects with MDD and 20 healthy controls (individually matched on age +/-3 years, gender and ethnicity) participated and completed all procedures. The individuals with MDD and 18 of the controls have been described in other publications using different measures and testing different hypotheses (Wolkowitz et al.,2012).",0,NA,0,NA,unreported,unreported,0,childunreported,unreported,unreported,both,20,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Adverse childhood experience in MDD sufferers,LTL base pairs,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,NA,,-0.13,0.050867664
117,485,m,colter2014,colter,2014,"Social disadvantage, genetic sensitivity, and children’s telomere length",homo sapiens,"Growing up in a harsh environment (vs a nurturing environment: environment quaility measures comprised: Average poverty ratio, harsh parenting index, family structure changes, mother's age at birth, mother's education and age 9 BMI)",psychosocial,other negative,more adversity,Mean age = 9,3285,"5,110",child,44712.5,unreported,"40, 9-y-old African American boys participating in the Fragile Families and Child Wellbeing Study",0,NA,0,NA,3285,child,1,childchild,0,40,male,40,saliva,buccal,qpcr,0,0,NA,1,negative,HarshEnvironment.NurturingEnvironment,Saliva TL (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.206150022,9.6,10.3,NA,NA,4.1,2.5,20,20,NA,NA,NA,NA,NA,,-0.102531778,0.025104743
118,486,m,damjanovic2007,damjanovic,2007,Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients,homo sapiens,Cargiving to Alzheimers patients ,psychosocial,caregiving,more adversity,65±1 years,23725,4927.5,adult,44712.5,1898,"Eighty-two subjects: 41 caregivers of (spouses or offspring of AD patients) who endured chronic psychological stress & 41 age- and gender-matched controls. They were part of a
larger study on caregiver stress, immune function, and health.",0,NA,0,NA,23725,adult,1,adultadult,60,22,both,82,monocytes,wbcs,southernblot,0,0,NA,0,negative,AlzheimersCaregivers.controls,Monocyte mTRF (kb),negative,0,meansse,1,NA,NA,NA,NA,-0.312347524,5.7,5.9,0.1,0.1,0.640312424,0.640312424,41,41,NA,NA,NA,NA,NA,,-0.15430335,0.011764788
119,487,m,damjanovic2007,damjanovic,2007,Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients,homo sapiens,Cargiving to Alzheimers patients ,psychosocial,caregiving,more adversity,65±1 years,23725,4927.5,adult,44712.5,1898,"Eighty-two subjects: 41 caregivers of (spouses or offspring of AD patients) who endured chronic psychological stress & 41 age- and gender-matched controls. They were part of a
larger study on caregiver stress, immune function, and health.",0,NA,0,NA,23725,adult,1,adultadult,60,22,both,82,tcells,wbcs,southernblot,0,0,NA,0,negative,AlzheimersCaregivers.controls,T-cell mTRF (kb),negative,0,meansse,1,NA,NA,NA,NA,-0.156173762,6.3,6.5,0.2,0.2,1.280624847,1.280624847,41,41,NA,NA,NA,NA,NA,,-0.077849894,0.012196488
120,488,m,damjanovic2007,damjanovic,2007,Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients,homo sapiens,Cargiving to Alzheimers patients ,psychosocial,caregiving,more adversity,65±1 years,23725,4927.5,adult,44712.5,1898,"Eighty-two subjects: 41 caregivers of (spouses or offspring of AD patients) who endured chronic psychological stress & 41 age- and gender-matched controls. They were part of a
larger study on caregiver stress, immune function, and health.",0,NA,0,NA,23725,adult,1,adultadult,60,22,both,82,pbmcs,wbcs,southernblot,0,0,NA,1,negative,AlzheimersCaregivers.controls,PBMC mTRF (kb),negative,0,meansse,1,NA,NA,NA,NA,-0.312347524,6.2,6.4,0.1,0.1,0.640312424,0.640312424,41,41,NA,NA,NA,NA,NA,,-0.15430335,0.011764788
121,559,m,das2009,das,2009,Telomere length in human adults and high level natural background radiation,homo sapiens,Exposure to natural radiation (high),environmentalhazard,none,none,26.10 years (4.49),9526.5,4927.5,adult,44712.5,unreported,People living in high level natural radation and low-level natural radiation areas of Kerala,0,NA,0,NA,9526.5,adult,1,adultadult,169,141,both,113,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Radiation >5mGy vs. <=1.5mGY,T/S ratio,negative,1,meanssd,1,NA,NA,NA,NA,-0.721298727,1.12,1.22,NA,NA,0.11,0.15,36,77,NA,NA,NA,NA,NA,,-0.318563857,0.00720833
122,560,m,das2009,das,2009,Telomere length in human adults and high level natural background radiation,homo sapiens,Exposure to natural radiation (medium),environmentalhazard,none,none,26.10 years (4.49),9526.5,4927.5,adult,44712.5,unreported,People living in high level natural radation and low-level natural radiation areas of Kerala,0,NA,0,NA,9526.5,adult,1,adultadult,169,141,both,127,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Radiation 3.01-5mGy vs. <=1.5mGY,T/S ratio,negative,1,meanssd,1,NA,NA,NA,NA,-1.100324307,1.08,1.22,NA,NA,0.08,0.15,50,77,NA,NA,NA,NA,NA,,-0.473501375,0.004776668
123,561,m,das2009,das,2009,Telomere length in human adults and high level natural background radiation,homo sapiens,Exposure to natural radiation (mild),environmentalhazard,none,none,26.10 years (4.49),9526.5,4927.5,adult,44712.5,unreported,People living in high level natural radation and low-level natural radiation areas of Kerala,0,NA,0,NA,9526.5,adult,1,adultadult,169,141,both,224,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Radiation 1.51-3 mGy vs. <=1.5mGY,T/S ratio,negative,1,meanssd,1,NA,NA,NA,NA,-0.666666667,1.12,1.22,NA,NA,0.15,0.15,147,77,NA,NA,NA,NA,NA,,-0.301867952,0.003704283
124,651,m,defelice2012,defelice,2012,Telomere shortening in women resident close to waste landfill sites,homo sapiens,Proximity to toxic waste dumping sites,environmentalhazard,none,none,Around 30 years,10950,"4,745",adult,44712.5,unreported,Pregnant women who had therapeutic abortion from Southern Italy,0,NA,0,NA,10950,adult,1,adultadult,50,0,female,50,wholeblood,wbcs,qpcr,0,0,NA,1,positive,Proximity to toxic waste dumping sites (km),T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.954,NA,NA,NA,NA,"For consistency with other environmental hazard exposure variables, ""Distance from toxic waste dumping sites"" has been recoded as ""Proximity to toxic waste dumping sites"", with the effect direction reversed (so that an increase in the variable corresponds to increased exposure).",0.954,0.00016488
125,365,m,degerman2014,degerman,2014,Long Leukocyte Telomere Length at Diagnosis Is a Risk Factor for Dementia Progression in Idiopathic Parkinsonism,homo sapiens,Parkinson’s disease status,disease,parkinsons,none,Mean age = 70.5,25732.5,4927.5,adult,44712.5,501.875,"136 patients diagnosed with PD + 30 healthy controls in the NYPUM-project (NY [new] Parkinsonism in UMea°), a prospective population-based study on idiopathic parkinsonism in northern Sweden.",0,NA,0,NA,25732.5,adult,1,adultadult,70,96,both,154,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Parkinson's disease status,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.34908074,0.77,0.82,NA,NA,0.15,0.11,124,30,NA,NA,NA,NA,NA,,-0.136951009,0.006293076
126,339,m,demissie2006,demissie,2006,"Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study",homo sapiens,Insulin resistance - Homeostatic Model Assessment of Insulin Resistance (HOMA-IR),disease,diabetes,none,Mean = 62.2 years,22578.6,"5,110",adult,44712.5,unreported,327 Caucasian men with a mean age of 62.2 years (range 40–89 years) from the Offspring cohort of the Framingham Heart Study,1,vasan2008,0,NA,22578.6,adult,1,adultadult,0,327,male,327,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Insulin resistance,Leukocyte TRF,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.16,NA,NA,NA,NA,,-0.16,0.00291244
127,678,m,dikercohen2013,dikercohen,2013,The effect of chemotherapy on telomere dynamics: Clinical results and possible mechanisms,homo sapiens,Chemotherapy (standard),medicaltreatment,none,none,"30-70 years, no more detail given",18250,4927.5,adult,44712.5,273.75,non-Hodgkin lymphoma patients and controls,0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,38,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Chemotherapy (standard) plus lymphoma,Mean TL in bp,negative,0,meanssd,1,NA,NA,NA,NA,-12.28494528,3408,5230,NA,NA,65,179,14,24,NA,NA,NA,NA,NA,,-0.986058963,2.07E-05
128,679,m,dikercohen2013,dikercohen,2013,The effect of chemotherapy on telomere dynamics: Clinical results and possible mechanisms,homo sapiens,Chemotherapy (intensive),medicaltreatment,none,none,"30-70 years, no more detail given",18250,4927.5,adult,44712.5,273.75,non-Hodgkin lymphoma patients and controls,0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,34,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Chemotherapy (intensive) plus lymphoma,Mean TL in bp,negative,0,meanssd,1,NA,NA,NA,NA,-15.66932497,2807,5230,NA,NA,56,179,10,24,NA,NA,NA,NA,NA,,-0.990333196,1.12E-05
129,680,m,dikercohen2013,dikercohen,2013,The effect of chemotherapy on telomere dynamics: Clinical results and possible mechanisms,homo sapiens,Chemotherapy (5-FU),medicaltreatment,none,none,"30-70 years, no more detail given",18250,4927.5,adult,44712.5,273.75,colon cancer patients and controls,0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,34,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Chemotherapy (standard) plus lymphoma,Mean TL in bp,negative,0,meanssd,1,NA,NA,NA,NA,-18.07107638,2395,5230,NA,NA,75,179,10,24,NA,NA,NA,NA,NA,,-0.99270582,6.40E-06
130,681,m,dikercohen2013,dikercohen,2013,The effect of chemotherapy on telomere dynamics: Clinical results and possible mechanisms,homo sapiens,Chemotherapy (Fludarabine),medicaltreatment,none,none,"30-70 years, no more detail given",18250,4927.5,adult,44712.5,273.75,colon cancer patients and controls,0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,32,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Chemotherapy (intensive) plus lymphoma,Mean TL in bp,negative,0,meanssd,1,NA,NA,NA,NA,-17.78490001,2357,5230,NA,NA,81,179,8,24,NA,NA,NA,NA,NA,,-0.991674396,8.87E-06
131,672,m,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (medium vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,4927.5,child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,39,41,both,63,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (medium 1 event vs. low 0 events),Buccal cell T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.64075,NA,NA,NA,NA,NA,NA,29,34,NA,NA,-0.2563,NA,0.4,,-0.304226458,0.013281592
132,673,m,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (high vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,4927.5,child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,39,41,both,51,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (high >1 event vs. low 0 events),Buccal cell T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.69275,NA,NA,NA,NA,NA,NA,17,34,NA,NA,-0.2771,NA,0.4,,-0.310431735,0.016331021
133,674,sg672,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (medium vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,"4,745",child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,39,0,female,26,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (medium 1 event vs. low 0 events),Buccal cell T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-1.08025,NA,NA,NA,NA,NA,NA,13,13,NA,NA,-0.4321,NA,0.4,,-0.475234065,0.023972489
134,675,sg673,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (high vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,"4,745",child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,39,0,female,26,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (high >1 event vs. low 0 events),Buccal cell T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-1.11325,NA,NA,NA,NA,NA,NA,13,13,NA,NA,-0.4453,NA,0.4,,-0.486356821,0.023314666
135,676,sg672,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (medium vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,"5,110",child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,0,41,male,31,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (medium 1 event vs. low 0 events),Buccal cell T/S ratio,positive,1,dbeta,1,NA,NA,NA,NA,0.04575,NA,NA,NA,NA,NA,NA,10,21,NA,NA,0.0183,NA,0.4,,0.021381578,0.033302862
136,677,sg673,drury2014,drury,2014,The association of telomere length with family violence and disruption,homo sapiens,Family instability (high vs. low),psychosocial,other negative,more adversity,10.2 ± 3.9 years,3723,"5,110",child,44712.5,unreported,Children from greater New Orleans,0,NA,0,NA,3723,child,1,childchild,0,41,male,31,buccal,buccal,qpcr,0,0,NA,1,negative,Family instability (high >1 event vs. low 0 events),Buccal cell T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.2915,NA,NA,NA,NA,NA,NA,10,21,NA,NA,-0.1166,NA,0.4,,-0.135017924,0.032129088
137,416,m,eerola2010,eerola,2010,No Evidence for Shorter Leukocyte Telomere Length in Parkinson’s Disease Patients,homo sapiens,Parkinson’s disease status,disease,parkinsons,none,Mean age = 66.5,24272.5,4927.5,adult,44712.5,unreported,"147 patients (87 men and 60 women) with idiopathic PD, all except 2 of whom were of Finnish origin + control group of patients’ spouses, who were neurologically healthy (n = 137; 87 women and 50 men).",0,NA,0,NA,24272.5,adult,1,adultadult,147,137,both,284,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Parkinson's disease status,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.08,NA,NA,NA,,0.13,0.003415143
138,683,m,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Bipolar II disorder vs. control,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients and healthy controls from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,38,18,both,56,pbmcs,wbcs,qfish,0,0,NA,0,negative,Bipolar II disorder vs. control,Mean telomere length  in bp,negative,0,ttest,1,NA,NA,1.44,55,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.190609639,0.016884654
139,684,ss683,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Bipolar II disorder vs. control,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients and healthy controls from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,38,18,both,56,pbmcs,wbcs,qfish,0,0,NA,1,positive,Bipolar II disorder vs. control,Load of short (<3kb) telomeres,negative,0,ttest,1,NA,NA,1.79,55,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.234626057,0.016235121
140,685,m,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Number of depressive episodes,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,0,negative,Number of depressive episodes,Mean telomere length  in bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.35,NA,NA,NA,NA,,-0.35,0.02851875
141,686,ss685,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Number of depressive episodes,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,1,positive,Number of depressive episodes,Load of short (<3kb) telomeres,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.45,NA,NA,NA,NA,,0.45,0.023555787
142,687,m,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Number of hypomanic episodes,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,0,negative,Number of hypomanic episodes,Mean telomere length  in bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.18,NA,NA,NA,NA,,-0.18,0.034675917
143,688,ss688,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Number of hypomanic episodes,psychiatric,depression and anxiety,depression,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,0,positive,Number of hypomanic episodes,Load of short (<3kb) telomeres,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.22,NA,NA,NA,NA,,0.22,0.033538613
144,689,m,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Smoking,smoking,none,none,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,0,negative,Smoking,Mean telomere length  in bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.08,NA,NA,NA,,0.13,0.035795763
145,690,ss689,elvashagen2011,elvashagen,2011,The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder,homo sapiens,Smoking,smoking,none,none,34.8 ± 7.7 years ,12702,4927.5,adult,44712.5,6935,Bipolar II patients from Oslo area,0,NA,0,NA,12702,adult,1,adultadult,19,9,both,28,pbmcs,wbcs,qfish,0,0,NA,0,positive,Smoking,Load of short (<3kb) telomeres,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.03702963
146,503,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Severe prenatal stressor,psychosocial,other negative,more adversity,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Severe prenatal stressor,T/S ratio,negative,0,dbeta,1,NA,NA,NA,NA,-0.411111111,NA,NA,NA,NA,NA,NA,45,49,NA,NA,-0.074,NA,0.18,,-0.201170828,0.009899983
147,504,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Birth weight percentile,other,birth weight or term,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,1,positive,Birth weight percentile,T/S ratio,positive,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,22,72,NA,0.2835,0.002,25.515,0.18,,0.3335,0.008493827
148,505,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Early post-natal trauma,psychosocial,traumatic experience,more adversity,juvenile,unreported,4927.5,child,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,childadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Early post-natal trauma,T/S ratio,negative,0,dbeta,1,NA,NA,NA,NA,-0.172222222,NA,NA,NA,NA,NA,NA,22,72,NA,NA,-0.031,NA,0.18,,-0.072725611,0.010639247
149,506,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Maternal care,parentalcare,more parental care,none,juvenile,unreported,4927.5,child,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,childadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Maternal care,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.14325,-0.003,8.595,0.18,,-0.14325,0.010315914
150,507,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Chronic stress,psychosocial,stress,more adversity,24.5 years(sd 0.7),8942.5,4927.5,adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Chronic stress,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.094222222,-0.032,0.53,0.18,,-0.094222222,0.010562615
151,508,m,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Depressive symptoms,psychosocial,mood,more adversity,24.5 years(sd 0.7),8942.5,4927.5,adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,73,21,both ,94,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Depressive symptoms,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.120916667,-0.003,7.255,0.18,,-0.120916667,0.01044056
152,509,sg503,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Severe prenatal stressor,psychosocial,other negative,more adversity,embryonic,embryonic,"4,745",embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,73,0,female,73,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Severe prenatal stressor,T/S ratio,negative,0,dbeta,1,NA,NA,NA,NA,-0.677777778,NA,NA,NA,NA,NA,NA,38,35,NA,NA,-0.122,NA,0.18,,-0.320716047,0.011178644
153,510,sg504,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Birth weight,other,birth weight or term,none,embryonic,embryonic,"4,745",embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,73,0,female,73,wholeblood,wbcs,qpcr,0,0,NA,1,positive,Birth weight percentile,T/S ratio,positive,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.2835,0.002,25.515,0.18,,0.3335,0.010971193
154,511,sg506,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Maternal care,parentalcare,more parental care,none,juvenile,unreported,"4,745",child,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,childadult,73,0,female,73,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Maternal care,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.14325,-0.003,8.595,0.18,,-0.14325,0.013324722
155,512,sg507,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Chronic stress,psychosocial,stress,more adversity,24.5 years(sd 0.7),8942.5,"4,745",adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,73,0,female,73,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Chronic stress,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.094222222,-0.032,0.53,0.18,,-0.094222222,0.013643377
156,513,sg508,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Depressive symptoms,psychiatric,depression and anxiety,depression,24.5 years(sd 0.7),8942.5,"4,745",adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,73,0,female,73,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Depressive symptoms,T/S ratio,positive,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.040305556,0.001,7.255,0.18,,0.090305556,0.013663282
157,514,sg503,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Severe prenatal stressor,psychosocial,other negative,more adversity,embryonic,embryonic,"5,110",embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,0,21,male,21,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Severe prenatal stressor,T/S ratio,positive,0,dbeta,1,NA,NA,NA,NA,0.388888889,NA,NA,NA,NA,NA,NA,7,14,NA,NA,0.07,NA,0.18,,0.180318968,0.046801368
158,515,sg504,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Birth weight,other,birth weight or term,none,embryonic,embryonic,"5,110",embryonic,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,embryonicadult,0,21,male,21,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Birth weight percentile,T/S ratio,positive,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.42525,0.003,25.515,0.18,,0.47525,0.029964439
159,516,sg506,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Maternal care,parentalcare,more parental care,none,juvenile,unreported,"5,110",child,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,0,childadult,0,21,male,21,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Maternal care,T/S ratio,positive,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.42975,0.009,8.595,0.18,,0.47975,0.029632676
160,517,sg507,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Chronic stress,psychosocial,stress,more adversity,24.5 years(sd 0.7),8942.5,"5,110",adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,0,21,male,21,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Chronic stress,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.318,-0.108,0.53,0.18,,-0.318,0.040398903
161,518,sg508,entringer2011,entringer,2011,Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood,homo sapiens,Depressive symptoms,psychiatric,depression and anxiety,depression,24.5 years(sd 0.7),8942.5,"5,110",adult,44712.5,unreported,"Volunteers from Trier, Germany",0,NA,0,NA,8942.5,adult,1,adultadult,0,21,male,21,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Depressive symptoms,T/S ratio,negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.241833333,-0.006,7.255,0.18,,-0.241833333,0.044322679
162,369,m,entringer2013,entringer,2013,Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length,homo sapiens,Pregnancy-specific stress (on newborn TL),psychosocial,other negative,more adversity,embryonic,embryonic,4927.5,embryonic,44712.5,280,"27 women - a subsample from a larger cohort of women attending prenatal care at a university-based clinic in Pittsburgh, PA.",0,NA,0,NA,8760,adult,0,embryonicadult,unreported,unreported,both,27,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Pregnancy-specific stress score,LTL (T/S ratio),negative,0,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.318378378,-0.062,1.9,0.37,,-0.318378378,0.031059432
163,370,m,epel2004,epel,2004,Accelerated telomere shortening in response to life stress,homo sapiens,Perceived stress,psychosocial,stress,more adversity,20–50 years,13870,"4,745",adult,44712.5,unreported,"58 healthy premenopausal women who were biological mothers of either a healthy child (n 19, ‘‘control mothers’’) or a chronically ill child (n 39, ‘‘caregiving mothers’’).",0,NA,0,NA,13870,adult,1,adultadult,54,0,female,54,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived stress scale,PBMC T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.31,NA,NA,NA,NA,,-0.31,0.015415759
164,371,m,epel2004,epel,2004,Accelerated telomere shortening in response to life stress,homo sapiens,Years of caregiving,psychosocial,caregiving,more adversity,20–50 years,13870,"4,745",adult,44712.5,NA,"58 healthy premenopausal women who were biological mothers of either a healthy child (n 19, ‘‘control mothers’’) or a chronically ill child (n 39, ‘‘caregiving mothers’’).",0,NA,0,NA,13870,adult,1,adultadult,36,0,female,36,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Years of caregiving,PBMC T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.4,NA,NA,NA,NA,"The IV was length of exposure, so the ""LengthExposure"" variable was recorded as ""NA""",-0.4,0.02016
165,713,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Mind-wandering tendency,psychosocial,stress,more adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,239,0,female,239,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Mind-wandering tendency,Leucocyte T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.19,NA,NA,NA,NA,,-0.19,0.003903795
166,714,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Depression,psychiatric,depression and anxiety,depression,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,198,0,female,198,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Depression,Leucocyte T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.09,NA,NA,NA,NA,,-0.09,0.004994242
167,715,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Perceived stress,psychosocial,stress,more adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,239,0,female,239,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Perceived stress,Leucocyte T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.09,NA,NA,NA,NA,,-0.09,0.004133889
168,716,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Rumination ,psychosocial,other negative,more adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,239,0,female,239,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Rumination ,Leucocyte T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.1,NA,NA,NA,NA,,-0.1,0.004118067
169,717,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Life satisfaction,psychosocial,other positive,less adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,239,0,female,239,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Life satisfaction,Leucocyte T/S ratio,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.05,NA,NA,NA,NA,,0.05,0.004180699
170,718,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Mind-wandering tendency,psychosocial,other negative,more adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,48,0,female,48,lymphocytes,wbcs,flowfish,0,0,NA,0,negative,Mind-wandering tendency,Lymphocyte TL ,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.41,NA,NA,NA,NA,,-0.41,0.01472463
171,719,m,epel2013,epel,2013,Wandering minds and aging cells,homo sapiens,Mind-wandering tendency,psychosocial,other negative,more adversity,57 ± 4.4 years ,20805,"4,745",adult,44712.5,unreported,Healthy female mild-life volunteers from San Fransisco Bay Area,0,NA,0,NA,20805,adult,1,adultadult,48,0,female,48,granulocytes,wbcs,flowfish,0,0,NA,0,negative,Mind-wandering tendency,Granulocyte TL,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.44,NA,NA,NA,NA,,-0.44,0.013835765
172,522,m,farhat2008,farhat,2008,Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers,homo sapiens,current smoker vs. never,smoking,none,none,Average 63 years,22970.6545,4927.5,adult,44712.5,Unreported,Patients undergoing coronary artery bypass graft surgery,0,NA,0,NA,22970.6545,adult,1,adultadult,67,19,both ,46,endothelial cells,other,southernblot,0,0,NA,0,negative,current smoker vs. never,TL in kilobase pairs,positive,0,meansse,1,NA,NA,NA,NA,0.071197784,9,8.9,0.2,0.4,1.019803903,1.788854382,26,20,NA,NA,NA,NA,NA,,0.035272804,0.02216696
173,523,m,farhat2008,farhat,2008,Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers,homo sapiens,former smoker vs. never,smoking,none,none,Average 63 years,22970.6545,4927.5,adult,44712.5,Unreported,Patients undergoing coronary artery bypass graft surgery,0,NA,0,NA,22970.6545,adult,1,adultadult,67,19,both ,60,endothelial cells,other,southernblot,0,0,NA,0,negative,former smoker vs. never,TL in kilobase pairs,positive,0,meansse,1,NA,NA,NA,NA,0.214763266,9.3,8.9,0.3,0.4,1.897366596,1.788854382,40,20,NA,NA,NA,NA,NA,,0.100725492,0.016606978
174,382,m,fernández-Moreno2011,fernández-Moreno,2011,mtDNA haplogroup J Modulates telomere length and Nitric Oxide production,homo sapiens,Osteoarthritis ,disease,other,none,Mean age = 60.69,22151.85,4927.5,adult,44712.5,unreported,166 healthy controls (114 J and 52 non-J) and 79 OA patients (41 J and 38 non-J) in Spain,0,NA,0,NA,22151.85,adult,1,adultadult,143,102,both,245,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Osteoarthritics.Controls,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.078876068,0.986,1.008,NA,NA,0.261,0.287,79,166,NA,NA,NA,NA,NA,,-0.03684273,0.004087242
175,487,m,ferrari2015,ferrari,2015,Placental telomere shortening in stillbirth: a sign of premature senescence?,homo sapiens,Being stillborn (still birth vs term birth),other,other,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"42 unexplained stillbirths (>22 weeks), 43 term and 15 preterm live births, at the Policlinico Hospital of Modena (Italy).",0,NA,0,NA,0,embryonic,1,embryonicembryonic,50,35,both,85,placenta,other,qpcr,0,0,NA,1,negative,Stillbirth.TermBirth,Placental TL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.950580344,2.455,5.181,NA,NA,1.239,3.841,42,43,NA,NA,NA,NA,NA,,-0.429246399,0.007921953
176,488,m,ferrari2015,ferrari,2015,Placental telomere shortening in stillbirth: a sign of premature senescence?,homo sapiens,Preterm birth (preterm births vs term births),other,birth weight or term,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"42 unexplained stillbirths (>22 weeks), 43 term and 15 preterm live births, at the Policlinico Hospital of Modena (Italy).",0,NA,0,NA,0,embryonic,1,embryonicembryonic,32,26,both,58,placenta,other,qpcr,0,0,NA,1,negative,PretermBirth.TermBirth,Placental TL (T/S ratio),positive,0,meanssd,1,NA,NA,NA,NA,0.277756605,6.382,5.181,NA,NA,5.525,3.841,15,43,NA,NA,NA,NA,NA,,0.120733475,0.017036129
177,353,m,fitzpatrick2006,fitzpatrick,2006,Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study,homo sapiens,Diabetes status,disease,diabetes,none,Mean age = 74.2,27083,4927.5,adult,44712.5,unreported,"419 Cardiovascular Health Study (CHS) participants completing the 1992/1993 clinic examination were randomly selected from 1,230participants who consented to DNA preparation/use, had at least 12 lg of DNA available, and had stored leukocytes for additional DNA preparation.",0,NA,0,NA,27083,adult,1,adultadult,247,172,both,367,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Diabetes status,LTL TRF (kbp),negative,1,dbeta,1,NA,NA,NA,NA,-0.258064516,NA,NA,NA,NA,NA,NA,74,293,NA,NA,-0.16,NA,0.62,"SDDV (TRF) was reported differently in the table (0.4) to the text (0.62). The value from the text was taken, to be more conservative.",-0.102990298,0.002674586
178,354,m,fitzpatrick2006,fitzpatrick,2006,Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study,homo sapiens,Hypertension ,disease,cardiovascular,none,Mean age = 74.2,27083,4927.5,adult,44712.5,unreported,"419 Cardiovascular Health Study (CHS) participants completing the 1992/1993 clinic examination were randomly selected from 1,230participants who consented to DNA preparation/use, had at least 12 lg of DNA available, and had stored leukocytes for additional DNA preparation.",0,NA,0,NA,27083,adult,1,adultadult,247,172,both,357,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Hypertensive status,LTL TRF (kbp),negative,1,dbeta,1,NA,NA,NA,NA,-0.024193548,NA,NA,NA,NA,NA,NA,189,168,NA,NA,-0.015,NA,0.62,"SDDV (TRF) was reported differently in the table (0.4) to the text (0.62). The value from the text was taken, to be more conservative.",-0.012074947,0.00280817
179,355,m,fitzpatrick2006,fitzpatrick,2006,Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study,homo sapiens,Smoking status (current smoker),smoking,none,none,Mean age = 74.2,27083,4927.5,adult,44712.5,NA,"419 Cardiovascular Health Study (CHS) participants completing the 1992/1993 clinic examination were randomly selected from 1,230participants who consented to DNA preparation/use, had at least 12 lg of DNA available, and had stored leukocytes for additional DNA preparation.",0,NA,0,NA,27083,adult,1,adultadult,247,172,both,240,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Current smoking,LTL TRF (kbp),negative,1,dbeta,1,NA,NA,NA,NA,-0.148387097,NA,NA,NA,NA,NA,NA,44,196,NA,NA,-0.092,NA,0.62,"SDDV (TRF) was reported differently in the table (0.4) to the text (0.62). The value from the text was taken, to be more conservative.",-0.057322428,0.004156649
180,720,m,formichi2014,formichi,2014,Weight loss associated with bariatric surgery does not restore short telomere length of severe obese patients after 1 year,homo sapiens,Metabolic syndrome,disease,other,none,42.43±10.9 years,15486.95,4927.5,adult,44712.5,unreported,Obese patients from Italy,0,NA,0,NA,15486.95,adult,1,adultadult,85,22,both,107,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Metabolic syndrome vs. not,Leucocyte TL,positive,0,meanssd,1,NA,NA,NA,NA,0.212923094,0.97,0.91,NA,NA,0.29,0.27,62,45,NA,NA,NA,NA,NA,,0.104533433,0.009228914
181,192,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Unemployment/being on unemployment leave (vs being full-time employed),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,415,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Unemployed.FullTimeEmployed,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,55,360,NA,-0.0121,NA,NA,0.176,,-0.0121,0.002414752
182,193,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Part time employment (vs being full-time employed),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,428,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PartTimeEmployed.FullTimeEmployed,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,68,360,NA,0.0107,NA,NA,0.176,,0.0607,0.002324695
183,194,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Being retired & not working/being a homemaker (vs being full-time employed),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,762,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Retired.FullTimeEmployed,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,402,360,NA,-4.00E-04,NA,NA,0.176,,-4.00E-04,0.00131406
184,195,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Being retired & working/volunteering (vs being full-time employed),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,456,leukocytes,wbcs,qpcr,0,0,NA,0,negative,RetiredVolunteers.FullTimeEmployed,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,96,360,NA,0.0099,NA,NA,0.176,,0.0599,0.002182059
185,196,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Occupation: blue-collar (vs management),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,346,leukocytes,wbcs,qpcr,0,0,NA,0,negative,BlueCollar.Management,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,236,110,NA,-0.0085,NA,NA,0.176,,-0.0085,0.002898132
186,197,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,"Occupation: sales, office, admin support (vs management)",socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,308,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Admin.Management,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,198,110,NA,-0.0074,NA,NA,0.176,,-0.0074,0.003256972
187,198,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Occupation: service (vs management),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,342,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Service.Management,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,232,110,NA,-0.0205,NA,NA,0.176,,-0.0205,0.002930087
188,199,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Occupation: professional (vs management),socioeconomic,occupation or employment status,lower,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,514,467,both,316,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Professional.Management,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,206,110,NA,-0.0252,NA,NA,0.176,,-0.0252,0.003170572
189,200,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Physically active job,physicalactivity,more activity,none,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,215,467,both,981,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Physical activity at work,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.0019,NA,1,0.176,,-0.0019,0.001020401
190,201,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Hazard exposure on the job,environmentalhazard,none,none,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,215,467,both,981,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Exposure to hazards at work,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.0085,NA,1,0.176,,0.0585,0.001013436
191,202,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Interpersonal stress exposure on the job,psychosocial,work-related stress,more adversity,Mean age = 61.4,22411,4927.5,adult,44712.5,unreported,"981 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,22411,adult,1,adultadult,215,467,both,981,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Intepersonal stess at work,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-7.00E-04,NA,1,0.176,,-7.00E-04,0.001020407
192,203,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,High strain job (vs low strain job),psychosocial,work-related stress,more adversity,Mean age = 55.4,20221,4927.5,adult,44712.5,5110,"435 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,20221,adult,1,adultadult,215,220,both,227,leukocytes,wbcs,qpcr,0,0,NA,0,negative,HighStrainJob.LowStrainJob,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,122,105,NA,0.0034,NA,NA,0.181,,0.0534,0.00439958
193,204,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Active job (vs low strain job),psychosocial,work-related stress,more adversity,Mean age = 55.4,20221,4927.5,adult,44712.5,5110,"435 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,20221,adult,1,adultadult,215,220,both,203,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ActiveJob.LowStrainJob,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,98,105,NA,0.0099,NA,NA,0.181,,0.0599,0.004915034
194,205,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Passive job (vs low strain job),psychosocial,work-related stress,more adversity,Mean age = 55.4,20221,4927.5,adult,44712.5,5110,"435 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,20221,adult,1,adultadult,215,220,both,216,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PassiveJob.LowStrainJob,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,111,105,NA,0.0142,NA,NA,0.181,,0.0642,0.004612901
195,206,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Degree of job control (O*NET),psychosocial,work-related stress,less adversity,Mean age = 55.4,20221,4927.5,adult,44712.5,5110,"435 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,20221,adult,1,adultadult,215,220,both,435,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Control at work,LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.0029,NA,1,0.181,,-0.0029,0.002304109
196,207,m,fujishiro2012,fujishiro,2012,"Current employment status, occupational category, occupational hazard exposure and job stress in relation to telomere length: The multiethnic study of atherosclerosis (MESA)",homo sapiens,Degree of job demand (O*NET),psychosocial,work-related stress,more adversity,Mean age = 55.4,20221,4927.5,adult,44712.5,5110,"435 adults, aged between 45 years and 84 years, free of clinical CVD in six US communities, from MESA, the Multiethnic Study of Atherosclerosis.",0,NA,0,NA,20221,adult,1,adultadult,215,220,both,435,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Demands at work,LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.0089,NA,1,0.181,,-0.0089,0.002303782
197,223,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,"Calorie intake, kcal/g",nutrition,carbohydrates,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Calorie intake, kcal/g",ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.057,NA,NA,NA,,-0.057,0.00347382
198,224,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Dietary total antioxidant capacity,nutrition,other,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Dietary total antioxidant capacity,ln-transformed LTL T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.157,NA,NA,NA,NA,,0.157,0.003326257
199,225,ss223,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,"Glycaemic load, units",nutrition,carbohydrates,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,1,none,"Glycaemic load, units",ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.131,NA,NA,NA,,-0.131,0.003377526
200,226,ss223,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,"Carbohydrate intake, %E",nutrition,carbohydrates,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Carbohydrate intake, %E",ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.093,NA,NA,NA,,-0.093,0.003436283
201,227,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,"Protein, % E",nutrition,protein,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Protein, % E",ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.022,NA,NA,NA,,0.072,0.003460346
202,228,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,"Fat, % E",nutrition,fats and oils,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Fat, % E",ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.096,NA,NA,NA,,0.146,0.003349029
203,229,ss228,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Monounsaturated fatty acid intake,nutrition,fats and oils,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Monounsaturated fatty acid intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.08,NA,NA,NA,,0.13,0.00337932
204,230,ss228,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Polyunsaturated fatty acid intake,nutrition,fats and oils,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Polyunsaturated fatty acid intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.106,NA,NA,NA,,0.156,0.003328392
205,231,ss228,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Saturated fatty acid intake,nutrition,fats and oils,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Saturated fatty acid intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.082,NA,NA,NA,,0.132,0.003375719
206,232,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Legume intake,nutrition,"fruit, legumes and vegetables",none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,1,none,Legume intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.117,NA,NA,NA,,0.167,0.003304195
207,233,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Vegetable intake,nutrition,"fruit, legumes and vegetables",none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Vegetable intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.015,NA,NA,NA,,0.065,0.00346702
208,234,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Fruit intake,nutrition,"fruit, legumes and vegetables",none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Fruit intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.063,NA,NA,NA,,0.113,0.00340778
209,235,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Fish intake,nutrition,"meat, fish and eggs",none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Fish intake,ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.03,NA,NA,NA,,-0.03,0.003490213
210,236,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Meat intake,nutrition,"meat, fish and eggs",none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Meat intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.043,NA,NA,NA,,0.093,0.003436283
211,237,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Dairy intake,nutrition,dairy,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Dairy intake,ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.088,NA,NA,NA,,-0.088,0.003442559
212,238,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Sweets and sugary beverage intake,nutrition,other,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,0,none,Sweets and sugary beverage intake,ln-transformed LTL T/S ratio,positive,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.006,NA,NA,NA,,0.056,0.003474608
213,239,m,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,Cereal intake,nutrition,grains,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,1,none,Cereal intake,ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.209,NA,NA,NA,,-0.209,0.003197713
214,240,ss239,garcía-calzón2015,garcía-calzón,2015,Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population,homo sapiens,White bread intake,nutrition,grains,none,Mean age = 11.5 years,4197.5,4927.5,child,44712.5,unreported,"A subsample of 287 Spanish children and adolescents (55% males, aged 6-18 yr) from the GENOI study (Grupo Navarro de Estudio de la Obesidad Infantil; GENOI)",0,NA,0,NA,4197.5,child,1,childchild,128,159,both,287,leukocytes,wbcs,qpcr,0,0,NA,1,none,White bread intake,ln-transformed LTL T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.209,NA,NA,NA,,-0.209,0.003197713
215,489,m,gardner2005,gardner,2005,Rise in Insulin Resistance Is Associated With Escalated Telomere Attrition,homo sapiens,"Diabetes (rise in insulin resistance, HOMA-IR, over time)",disease,diabetes,none,Average of mean ages between baseline and follow up = 32.075,11707.375,4927.5,adult,44712.5,4179.25,"22 white males, 28 white females, 8 black males, and 12 black females who participated in the 1988 to 1991 and 2000 to 2001 cross-sectional cardiovascular screenings of young adults of the Bogalusa Heart Study.",0,NA,0,NA,13815.25,adult,1,adultadult,40,30,both,70,leukocytes,wbcs,southernblot,0,1,NA,1,positive,Rise in insulin resistance,LTL TRF (kb),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.47,NA,NA,NA,NA,,-0.47,0.008797055
216,490,m,geiger2012,geiger,2012,Catching-up but telomere loss: Half-opening the black box of growth and ageing trade-off in wild king penguin chicks,aptenodytes patagonicus,Post-winter growth duration,other,other,,9.6 months on average,292,unavailable,juvenile,9490,NA,"14 large chicks and 44 small chicks in the colony of ‘La Grande Manchotiere’ (approximately 24 000 breeding pairs), Possession island, Crozet archipelago",0,NA,NA,213,373,juvenile,1,juvenilejuvenile,unreported,unreported,both,58,rbcs,rbcs,qpcr,0,1,NA,0,positive,Post-winter growth period (days),RBCTL loss ,negative,1,fanova,1,4.12,18.8,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.423976028,0.011803522
217,491,m,geiger2012,geiger,2012,Catching-up but telomere loss: Half-opening the black box of growth and ageing trade-off in wild king penguin chicks,aptenodytes patagonicus,Chick size after post-winter growth (being small),other,other,,12.3 months average,374,unavailable,juvenile,9490,NA,"14 large chicks and 44 small chicks in the colony of ‘La Grande Manchotiere’ (approximately 24 000 breeding pairs), Possession island, Crozet archipelago",0,NA,NA,213,373,juvenile,1,juvenilejuvenile,unreported,unreported,both,28,rbcs,rbcs,qpcr,0,1,NA,1,negative,LargeChicks.SmallChicks,RBCTL loss ,negative,1,meanssd,1,NA,NA,NA,NA,-2.95,-0.6,-0.01,NA,NA,0.2,0.2,14,14,NA,NA,NA,NA,NA,,-0.827708498,0.003672635
218,492,ss490,geiger2012,geiger,2012,Catching-up but telomere loss: Half-opening the black box of growth and ageing trade-off in wild king penguin chicks,aptenodytes patagonicus,Chick size before post-winter growth (being small),other,other,,2.5 months average,76,unavailable,juvenile,9490,NA,"14 large chicks and 44 small chicks in the colony of ‘La Grande Manchotiere’ (approximately 24 000 breeding pairs), Possession island, Crozet archipelago",0,NA,NA,213,373,juvenile,1,juvenilejuvenile,unreported,unreported,both,28,rbcs,rbcs,qpcr,0,0,NA,1,negative,LargeChicks.SmallChicks,RBCTL T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.85,1.48,1.31,NA,NA,0.2,0.2,14,14,NA,NA,NA,NA,NA,,0.39114064,0.026571268
219,361,m,georgin-lavialle2014,georgin-lavialle,2014,Leukocyte telomere length in mastocytosis: Correlations with depression and perceived stress,homo sapiens,Perceived stress scale (among mastocytosis patients),psychosocial,work-related stress,more adversity,Median age = 45,16425,4927.5,adult,44712.5,unreported,19 adults with a diagnosis of mastocytosis,0,NA,0,NA,16425,adult,1,adultadult,15,4,both,19,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Perceived Stress,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.728,NA,NA,NA,NA,,-0.728,0.012273058
220,362,m,georgin-lavialle2014,georgin-lavialle,2014,Leukocyte telomere length in mastocytosis: Correlations with depression and perceived stress,homo sapiens,Depression (among mastocytosis patients) - BDI-II score,psychiatric,depression and anxiety,depression,Median age = 45,16425,4927.5,adult,44712.5,unreported,19 adults with a diagnosis of mastocytosis,0,NA,0,NA,16425,adult,1,adultadult,15,4,both,19,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Depression,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.407,NA,NA,NA,NA,,-0.407,0.038674533
221,276,m,geronimus2010,geronimus,2010,Do US Black Women Experience Stress-Related Accelerated Biological Aging?,homo sapiens,"PSS-4, abbreviated Perceived Stress Scale",psychosocial,stress,more adversity,49-55 years,18980,"4,745",adult,44712.5,unreported,215 women between 49 and 55 years of age from the US Study of Women's Health Across the Nation (SWAN).,0,NA,0,NA,18980,adult,1,adultadult,215,0,female,215,pbmcs,wbcs,qpcr,0,0,NA,unreported,negative,Perceived Stress,PBMC bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,NA,,-0.07,0.004627215
222,277,m,geronimus2010,geronimus,2010,Do US Black Women Experience Stress-Related Accelerated Biological Aging?,homo sapiens,Poverty,socioeconomic,income,lower,49-55 years,18980,"4,745",adult,44712.5,unreported,215 women between 49 and 55 years of age from the US Study of Women's Health Across the Nation (SWAN).,0,NA,0,NA,18980,adult,1,adultadult,215,0,female,215,pbmcs,wbcs,qpcr,0,0,NA,unreported,negative,Poverty,PBMC bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.095,NA,NA,NA,NA,,-0.095,0.004588932
223,278,m,geronimus2010,geronimus,2010,Do US Black Women Experience Stress-Related Accelerated Biological Aging?,homo sapiens,Ever having smoked,smoking,none,none,49-55 years,18980,"4,745",adult,44712.5,unreported,215 women between 49 and 55 years of age from the US Study of Women's Health Across the Nation (SWAN).,0,NA,0,NA,18980,adult,1,adultadult,215,0,female,215,pbmcs,wbcs,qpcr,0,0,NA,unreported,negative,Ever smoking,PBMC bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.083,NA,NA,NA,NA,,-0.083,0.004608736
224,279,ss278,geronimus2010,geronimus,2010,Do US Black Women Experience Stress-Related Accelerated Biological Aging?,homo sapiens,Current smoking,smoking,none,none,49-55 years,18980,"4,745",adult,44712.5,unreported,215 women between 49 and 55 years of age from the US Study of Women's Health Across the Nation (SWAN).,0,NA,0,NA,18980,adult,1,adultadult,215,0,female,215,pbmcs,wbcs,qpcr,0,0,NA,unreported,negative,Current smoking,PBMC bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.061,NA,NA,NA,NA,,-0.061,0.004638186
225,483,m,grodstein2008,grodstein,2008,Shorter Telomeres May Mark Early Risk of Dementia: Preliminary Analysis of 62 Participants from the Nurses’ Health Study,homo sapiens,Dementia (dementia cases vs controls),disease,other,none,Mean age = 79.6,29054,"4,745",adult,44712.5,unreported,62 participants of the Nurses’ Health Study,1,mason2015,0,NA,29054,adult,1,adultadult,54,0,female,54,leukocytes,wbcs,qpcr,0,0,NA,1,negative,DementiaCases.Controls,PBL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.877166158,0.49,0.61,NA,NA,0.09,0.14,5,49,NA,NA,NA,NA,NA,,-0.246415781,0.016646142
226,484,m,grodstein2008,grodstein,2008,Shorter Telomeres May Mark Early Risk of Dementia: Preliminary Analysis of 62 Participants from the Nurses’ Health Study,homo sapiens,Mild cognitive impairment (MCI cases vs controls),disease,other,none,Mean age = 79.55,29035.75,"4,745",adult,44712.5,unreported,62 participants of the Nurses’ Health Study,1,mason2015,0,NA,29035.75,adult,1,adultadult,57,0,female,57,leukocytes,wbcs,qpcr,0,0,NA,1,negative,MildCognitiveImpairmentCases.Controls,PBL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.747017881,0.51,0.61,NA,NA,0.08,0.14,8,49,NA,NA,NA,NA,NA,,-0.251159807,0.015675299
227,485,m,guan2008,guan,2008,A percentage analysis of the telomere length in Parkinson's disease patients,homo sapiens,Parkinson’s disease,disease,parkinsons,none,47–69 years,21170,"5,110",adult,44712.5,unreported,"Male PD patients visiting the outpatient clinic of the Kyushu University Beppu Advanced Medical Center from April 2002 through March 2005 were enrolled, and some of their male family members and some of our hospital’s healthy male workers, who never smoked and passed a regular medical check-up within a year before the enrollment, were also enrolled as the normal controls.",0,NA,0,NA,21170,adult,1,adultadult,0,55,male,55,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Parkinson's disease status,mTRF,negative,0,meanssd,1,NA,NA,NA,NA,-0.260218195,7.55,7.94,NA,NA,1.69,1.27,28,27,NA,NA,NA,NA,NA,,-0.129000644,0.017907307
228,486,sg10,guan2008,guan,2008,A percentage analysis of the telomere length in Parkinson's disease patients,homo sapiens,Parkinson’s disease,disease,parkinsons,none,50-59 years,19892.5,"5,110",adult,44712.5,unreported,"Male PD patients visiting the outpatient clinic of the Kyushu University Beppu Advanced Medical Center from April 2002 through March 2005 were enrolled, and some of their male family members and some of our hospital’s healthy male workers, who never smoked and passed a regular medical check-up within a year before the enrollment, were also enrolled as the normal controls.",0,NA,0,NA,19892.5,adult,1,adultadult,0,23,male,23,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Parkinson's disease status,mTRF,positive,0,meanssd,1,NA,NA,NA,NA,0.051196827,8.11,8.04,NA,NA,1.51,1.29,8,15,NA,NA,NA,NA,NA,,0.024376804,0.045400541
229,487,sg10,guan2008,guan,2008,A percentage analysis of the telomere length in Parkinson's disease patients,homo sapiens,Parkinson’s disease,disease,parkinsons,none,60-69 years,21717.5,"5,110",adult,44712.5,unreported,"Male PD patients visiting the outpatient clinic of the Kyushu University Beppu Advanced Medical Center from April 2002 through March 2005 were enrolled, and some of their male family members and some of our hospital’s healthy male workers, who never smoked and passed a regular medical check-up within a year before the enrollment, were also enrolled as the normal controls.",0,NA,0,NA,21717.5,adult,1,adultadult,0,29,male,29,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Parkinson's disease status,mTRF,negative,0,meanssd,1,NA,NA,NA,NA,-0.617172838,7,7.81,NA,NA,1.36,1.24,17,12,NA,NA,NA,NA,NA,,-0.290826561,0.029928343
230,440,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (benign MS vs controls) in men,disease,other,none,Mean age = 32.35,11807.75,"5,110",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,11807.75,adult,1,adultadult,0,44,male,44,pbmcs,wbcs,southernblot,0,0,NA,0,negative,BenignMS.Controls,PBMC kb,positive,0,meanssd,1,NA,NA,NA,NA,0.744290686,9.7,8.4,NA,NA,1,1.9,10,34,NA,NA,NA,NA,NA,,0.297761865,0.019314807
231,441,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (secondary progressive MS vs controls)  in men,disease,other,none,Mean age = 30.85,11260.25,"5,110",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,11260.25,adult,1,adultadult,0,45,male,45,pbmcs,wbcs,southernblot,0,0,NA,0,negative,SecondaryProgressiveMS.Controls,PBMC kb,positive,0,meanssd,1,NA,NA,NA,NA,0.629666152,9.5,8.4,NA,NA,1.1,1.9,11,34,NA,NA,NA,NA,NA,,0.261208904,0.019731708
232,442,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (primarily progressive MS vs controls)  in men,disease,other,none,Mean age = 32.9,12008.5,"5,110",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,12008.5,adult,1,adultadult,0,45,male,45,pbmcs,wbcs,southernblot,0,0,NA,1,negative,PrimarilyProgressiveMS.Controls,PBMC kb,negative,0,meanssd,1,NA,NA,NA,NA,-1.137215907,6.5,8.4,NA,NA,0.3,1.9,11,34,NA,NA,NA,NA,NA,,-0.439092641,0.014808365
233,443,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (benign MS vs controls) in women,disease,other,none,Mean age = 36,13140,"4,745",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,13140,adult,1,adultadult,35,0,female,35,pbmcs,wbcs,southernblot,0,0,NA,0,negative,BenignMS.Controls,PBMC kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.316400095,9.3,10.1,NA,NA,0.3,2.9,9,26,NA,NA,NA,NA,NA,,-0.13698191,0.028318353
234,444,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (secondary progressive MS vs controls) in women,disease,other,none,Mean age = 35.8,13067,"4,745",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,13067,adult,1,adultadult,35,0,female,35,pbmcs,wbcs,southernblot,0,0,NA,0,negative,SecondaryProgressiveMS.Controls,PBMC kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.434473878,9,10.1,NA,NA,0.4,2.9,9,26,NA,NA,NA,NA,NA,,-0.186556947,0.027400126
235,445,m,guan2015,guan,2015,Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening,homo sapiens,Multiple sclerosis severity (primarily progressive MS vs controls) in women,disease,other,none,Mean age = 35.95,13121.75,"4,745",adult,44712.5,unreported,Fifty-nine patients with MS and 61 healthy controls,0,NA,0,NA,13121.75,adult,1,adultadult,35,0,female,35,pbmcs,wbcs,southernblot,0,0,NA,1,negative,PrimarilyProgressiveMS.Controls,PBMC kb,negative,0,meanssd,1,NA,NA,NA,NA,-1.20964838,7,10.1,NA,NA,0.9,2.9,9,26,NA,NA,NA,NA,NA,,-0.46738752,0.017965256
236,423,m,hardikar2015,hardikar,2015,Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus,homo sapiens,Cigarette pack-years (per pack-year) in people with Barrett’s esophagus,smoking,none,none,Mean age = 60.9,22228.5,4927.5,adult,44712.5,unreported,295 individuals diagnosed with Barrett’s esophagus (BE) between 1995 and 2009,0,NA,0,NA,22228.5,adult,1,adultadult,59,236,both,295,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smoking (cigarette pack-years),LTL (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.11,NA,NA,NA,NA,,-0.11,0.003319546
237,424,m,hardikar2015,hardikar,2015,Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus,homo sapiens,Alcoholic drinks/day (per drink) in people with Barrett’s esophagus,alcohol,more alcohol,none,Mean age = 60.9,22228.5,4927.5,adult,44712.5,unreported,295 individuals diagnosed with Barrett’s esophagus (BE) between 1995 and 2009,0,NA,0,NA,22228.5,adult,1,adultadult,59,236,both,295,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Alcohol intake,LTL (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,NA,,-0.07,0.003368109
238,425,m,hardikar2015,hardikar,2015,Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus,homo sapiens,NSAID use in people with Barrett’s esophagus,medicaltreatment,none,none,Mean age = 60.9,22228.5,4927.5,adult,44712.5,unreported,295 individuals diagnosed with Barrett’s esophagus (BE) between 1995 and 2009,0,NA,0,NA,22228.5,adult,1,adultadult,59,236,both,295,leukocytes,wbcs,qpcr,0,0,NA,0,none,NSAIDUsers.NonNSAIDUsers,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.001,NA,NA,NA,,-0.001,0.003401354
239,426,m,hardikar2015,hardikar,2015,Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus,homo sapiens,Statin use in people with Barrett’s esophagus,medicaltreatment,none,none,Mean age = 60.9,22228.5,4927.5,adult,44712.5,unreported,295 individuals diagnosed with Barrett’s esophagus (BE) between 1995 and 2009,0,NA,0,NA,22228.5,adult,1,adultadult,59,236,both,295,leukocytes,wbcs,qpcr,0,0,NA,0,none,StatinUsers.NonStatinUsers,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.023,NA,NA,NA,,-0.023,0.003397763
240,534,m,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Occupational social class,socioeconomic,occupation or employment status,higher,69.6 years,25404,4927.5,adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,525,both,1048,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Occupational social class,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.004,NA,NA,NA,,-0.004,0.000955079
241,535,m,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Years of education,socioeconomic,education,higher,69.6 years,25404,4927.5,adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,525,both,1048,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Years of education,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.018,NA,NA,NA,,-0.018,0.000954491
242,536,m,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Cigarettes smoked per day,smoking,none,none,69.6 years,25404,4927.5,adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,525,both,1048,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cigarettes smoked per day,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.004,NA,NA,NA,,-0.004,0.000955079
243,537,m,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Units of alcohol consumed per week,alcohol,more alcohol,none,69.6 years,25404,4927.5,adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,525,both,1048,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Units of alcohol consumed per week,T/S ratio converted to kbp,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.03,NA,NA,NA,,0.08,0.000942924
244,538,sg534,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Occupational social class,socioeconomic,occupation or employment status,higher,69.6 years,25404,"4,745",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,0,female,523,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Occupational social class,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.023,NA,NA,NA,,-0.023,0.001913683
245,539,sg535,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Years of education,socioeconomic,education,higher,69.6 years,25404,"4,745",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,0,female,523,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Years of education,T/S ratio converted to kbp,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.007,NA,NA,NA,,0.057,0.001903281
246,540,sg536,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Cigarettes smoked per day,smoking,none,none,69.6 years,25404,"4,745",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,0,female,523,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cigarettes smoked per day,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.076,NA,NA,NA,,-0.076,0.001893642
247,541,sg537,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Units of alcohol consumed per week,alcohol,more alcohol,none,69.6 years,25404,"4,745",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,523,0,female,523,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Units of alcohol consumed per week,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.011,NA,NA,NA,,-0.011,0.001915245
248,542,sg534,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Occupational social class,socioeconomic,occupation or employment status,higher,69.6 years,25404,"5,110",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,0,525,male,525,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Occupational social class,T/S ratio converted to kbp,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.012,NA,NA,NA,,0.062,0.001893753
249,543,sg535,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Years of education,socioeconomic,education,higher,69.6 years,25404,"5,110",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,0,525,male,525,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Years of education,T/S ratio converted to kbp,negative,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.041,NA,NA,NA,,-0.041,0.001901986
250,544,sg536,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Cigarettes smoked per day,smoking,none,none,69.6 years,25404,"5,110",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,0,525,male,525,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cigarettes smoked per day,T/S ratio converted to kbp,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.04,NA,NA,NA,,0.09,0.001877606
251,545,sg537,harris2012,harris,2012,Telomere length and aging biomarkers in 70-year-olds: The Lothian Birth Cohort 1936,homo sapiens,Units of alcohol consumed per week,alcohol,more alcohol,none,69.6 years,25404,"5,110",adult,44712.5,unreported,Lothian Birth Cohort of 1936,0,NA,0,NA,25404,adult,1,adultadult,0,525,male,525,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Units of alcohol consumed per week,T/S ratio converted to kbp,positive,0,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.055,NA,NA,NA,,0.105,0.001866549
252,695,m,hehar2016,hehar,2016,The use of telomere length as a predictive biomarker for injury prognosis in juvenile rats following a concussion/mild traumatic brain injury,rattus rattus,Concussion (experimentally induced),other,other,,30 days,30,101,juvenile,1533,1,Sprague Dawley rats,0,NA,NA,NA,30,juvenile,1,juvenilejuvenile,unreported,unreported,both,110,ear tissue,other,qpcr,1,0,NA,1,negative,Experimental concussion,T/S ratio from ear tissue,negative,0,fanova,1,17.64,109,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.373219081,0.00679649
253,696,m,hoen2013,hoen,2013,Association between anxiety but not depressive disorders and leukocyte telomere length after 2 years of follow-up in a population-based sample,homo sapiens,Composite International Diagnostic Interview (CIDI) for depression,psychiatric,depression and anxiety,depression,Mean = 53 years,19345,4927.5,adult,44712.5,unreported,"General population cohort of 974 participants, derived from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study.",0,NA,0,NA,21681,adult,1,adultadult,526,448,both,974,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Presence of depression ,LTL T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.01,NA,NA,NA,,0.06,0.001020363
254,697,ss41,hoen2013,hoen,2013,Association between anxiety but not depressive disorders and leukocyte telomere length after 2 years of follow-up in a population-based sample,homo sapiens,Composite International Diagnostic Interview (CIDI) for anxiety ,psychiatric,depression and anxiety,anxiety,Mean = 53 years,19345,4927.5,adult,44712.5,unreported,"General population cohort of 974 participants, derived from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study.",0,NA,0,17812,21681,adult,1,adultadult,526,448,both,974,leukocytes,wbcs,qpcr,0,1,NA,1,negative,Presence of anxiety other than GAD,LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.088,NA,NA,NA,,-0.088,0.001011893
255,698,m,hoen2013,hoen,2013,Association between anxiety but not depressive disorders and leukocyte telomere length after 2 years of follow-up in a population-based sample,homo sapiens,Composite International Diagnostic Interview (CIDI) for anxiety ,psychiatric,depression and anxiety,anxiety,Mean = 53 years,19345,4927.5,adult,44712.5,unreported,"General population cohort of 974 participants, derived from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study.",0,NA,0,NA,21681,adult,1,adultadult,526,448,both,974,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Presence of anxiety,LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.073,NA,NA,NA,,-0.073,0.001016825
256,699,ss41,hoen2013,hoen,2013,Association between anxiety but not depressive disorders and leukocyte telomere length after 2 years of follow-up in a population-based sample,homo sapiens,Composite International Diagnostic Interview (CIDI) for anxiety ,psychiatric,depression and anxiety,anxiety,Mean = 53 years,19345,4927.5,adult,44712.5,unreported,"General population cohort of 974 participants, derived from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study.",0,NA,0,17812,21681,adult,1,adultadult,526,448,both,974,leukocytes,wbcs,qpcr,0,1,NA,0,negative,Presence of GAD,LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.008,NA,NA,NA,,-0.008,0.001027618
257,565,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Education level low vs. high,socioeconomic,education,lower,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,272,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Education level low vs. high,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.278132894,1.3,1.39,0.025510204,0.030612245,0.316573306,0.332534098,154,118,NA,NA,NA,NA,NA,,-0.136551845,0.003553708
258,566,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Education level medium vs. high,socioeconomic,education,lower,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,262,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Education level medium vs. high,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.142002144,1.34,1.39,0.030612245,0.030612245,0.36734694,0.332534098,144,118,NA,NA,NA,NA,NA,,-0.070474932,0.003793453
259,567,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,H. pylori status positive vs. negative,disease,other,none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,415,leukocytes,wbcs,qpcr,0,0,NA,1,negative,H. pylori status positive vs. negative,T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-0.341310938,1.32,1.42,0.015306122,0.040816327,0.287168303,0.323969552,352,63,NA,NA,NA,NA,NA,,-0.121565607,0.002344594
260,568,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Pack years of smoking >30 versus none,smoking,none,none,Approx 65 years on average,23725,4927.5,adult,44712.5,NA,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,278,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Pack years of smoking >30 versus none,T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-0.367206806,1.26,1.38,0.030612245,0.025510204,0.323969549,0.328675987,112,166,NA,NA,NA,NA,NA,,-0.177254361,0.003386819
261,569,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Pack years of smoking 0.1-30 versus none,smoking,none,none,Approx 65 years on average,23725,4927.5,adult,44712.5,NA,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,303,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Pack years of smoking 0.1-30 versus none,T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-0.063403987,1.36,1.38,0.025510204,0.025510204,0.298589282,0.328675987,137,166,NA,NA,NA,NA,NA,,-0.031540759,0.003304673
262,570,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Years of drinking alcohol >29 versus nondrinker,alcohol,more alcohol,none,Approx 65 years on average,23725,4927.5,adult,44712.5,NA,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,192,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Years of drinking alcohol >29 versus nondrinker,T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-0.274460561,1.26,1.36,0.051020408,0.030612245,0.381801773,0.356997056,56,136,NA,NA,NA,NA,NA,,-0.123790928,0.005076369
263,571,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Years of drinking alcohol 10-29 versus nondrinker,alcohol,more alcohol,none,Approx 65 years on average,23725,4927.5,adult,44712.5,NA,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,221,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Years of drinking alcohol 10-29 versus nondrinker,T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-0.173098165,1.3,1.36,0.035714286,0.030612245,0.329269448,0.356997056,85,136,NA,NA,NA,NA,NA,,-0.083915961,0.004481663
264,572,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Years of drinking alcohol <10 versus nondrinker,alcohol,more alcohol,none,Approx 65 years on average,23725,4927.5,adult,44712.5,NA,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,273,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Years of drinking alcohol <10 versus nondrinker,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,0.027959896,1.37,1.36,0.030612245,0.030612245,0.358307141,0.356997056,137,136,NA,NA,NA,NA,NA,,0.013978489,0.003675034
265,573,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Fruit consumption rarely/never vs. daily/weekly,nutrition,"fruit, legumes and vegetables",none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,278,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Fruit consumption rarely/never vs. daily/weekly,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.31483096,1.26,1.37,0.035714286,0.025510204,0.311349927,0.362568121,76,202,NA,NA,NA,NA,NA,,-0.138957243,0.003472038
266,574,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Fruit consumption several times/month vs. daily/weekly,nutrition,"fruit, legumes and vegetables",none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,339,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Fruit consumption several times/month vs. daily/weekly,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.08870268,1.34,1.37,0.025510204,0.025510204,0.298589282,0.362568121,137,202,NA,NA,NA,NA,NA,,-0.043487252,0.0029474
267,575,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Vegetable consumption rarely/never vs. daily/weekly,nutrition,"fruit, legumes and vegetables",none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,290,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Vegetable consumption rarely/never vs. daily/weekly,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.183353151,1.29,1.35,0.056122449,0.020408163,0.354949533,0.32268139,40,250,NA,NA,NA,NA,NA,,-0.063099233,0.003432709
268,576,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Vegetable consumption several times/month vs. daily/weekly,nutrition,"fruit, legumes and vegetables",none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,372,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,Vegetable consumption several times/month vs. daily/weekly,T/S ratio,positive,1,meansse,1,NA,NA,NA,NA,-0.061010697,1.33,1.35,0.030612245,0.020408163,0.338123298,0.32268139,122,250,NA,NA,NA,NA,NA,,-0.028630893,0.002691001
269,577,m,hou2009,hou,2009,Telomere length in peripheral leukocyte DNA and gastric cancer risk,homo sapiens,Gastric cancer,disease,cancer,none,Approx 65 years on average,23725,4927.5,adult,44712.5,unreported,Newly reported gastric cancer cases and population controls from Warsaw,0,NA,0,NA,23725,adult,1,adultadult,248,468,both,716,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Gastric cancer case vs. control,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.260230292,1.25,1.34,NA,NA,0.34,0.35,300,416,NA,NA,NA,NA,NA,,-0.12735075,0.001353604
270,417,m,hudson2011,hudson,2011,No evidence of substantia nigra telomere shortening in Parkinson’s disease,homo sapiens,Parkinson’s disease status (pbmcs),disease,parkinsons,none,Mean age = 70.55,25750.75,4927.5,adult,44712.5,unreported,"109 community based cases with PD fulfilling UK-PD Society brain bank criteria for the diagnosis of PD (mean age 71.41 years, SD = 8.04, 61% male) from the North East of England to an ethnically age and gender matched control group (N = 99, mean age 69.69 years, SD = 7.88, 46% male), with no clinical evidence of PD. All were of Caucasian origin.  ",0,NA,0,NA,25750.75,adult,1,adultadult,96,112,both,208,pbmcs,wbcs,qpcr,0,0,NA,1,negative,ParkinsonsPatients.Controls,PBMC bp,positive,0,meanssd,0,NA,NA,NA,NA,3.004567761,4769,4087,NA,NA,234,219,109,99,NA,NA,NA,NA,NA,,0.832143567,0.000456904
271,418,m,hudson2011,hudson,2011,No evidence of substantia nigra telomere shortening in Parkinson’s disease,homo sapiens,Parkinson’s disease status (substantia niagra),disease,parkinsons,none,Mean age = 74.65,27247.25,4927.5,adult,44712.5,unreported,"109 community based cases with PD fulfilling UK-PD Society brain bank criteria for the diagnosis of PD (mean age 71.41 years, SD = 8.04, 61% male) from the North East of England to an ethnically age and gender matched control group (N = 99, mean age 69.69 years, SD = 7.88, 46% male), with no clinical evidence of PD. All were of Caucasian origin.  ",0,NA,0,NA,post-mortem,adult,1,adultadult,unreported,unreported,both,45,substantia niagra,other,qpcr,0,0,NA,0,negative,ParkinsonsPatients.Controls,Substantia niagra bp,positive,0,meanssd,0,NA,NA,NA,NA,0.824432462,7659,7256,NA,NA,366.7,644.4,28,17,NA,NA,NA,NA,NA,,0.371159283,0.016896799
272,420,sg417,hudson2011,hudson,2011,No evidence of substantia nigra telomere shortening in Parkinson’s disease,homo sapiens,Partkinson's disease status (males only),disease,parkinsons,none,Mean age = 70.55,25750.75,4927.5,adult,44712.5,unreported,"109 community based cases with PD fulfilling UK-PD Society brain bank criteria for the diagnosis of PD (mean age 71.41 years, SD = 8.04, 61% male) from the North East of England to an ethnically age and gender matched control group (N = 99, mean age 69.69 years, SD = 7.88, 46% male), with no clinical evidence of PD. All were of Caucasian origin.  ",0,NA,0,NA,25750.75,adult,1,adultadult,0,112,both,112,pbmcs,wbcs,qpcr,0,0,NA,0,negative,ParkinsonsPatients.Controls,PBMC bp,positive,0,meanssd,0,NA,NA,NA,NA,2.313578211,4935,4114,NA,NA,332.8,384.5,66,46,NA,NA,NA,NA,NA,,0.751241093,0.001709725
273,421,sg417,hudson2011,hudson,2011,No evidence of substantia nigra telomere shortening in Parkinson’s disease,homo sapiens,Partkinson's disease status (females only),disease,parkinsons,none,Mean age = 70.55,25750.75,4927.5,adult,44712.5,unreported,"109 community based cases with PD fulfilling UK-PD Society brain bank criteria for the diagnosis of PD (mean age 71.41 years, SD = 8.04, 61% male) from the North East of England to an ethnically age and gender matched control group (N = 99, mean age 69.69 years, SD = 7.88, 46% male), with no clinical evidence of PD. All were of Caucasian origin.  ",0,NA,0,NA,25750.75,adult,1,adultadult,96,0,both,96,pbmcs,wbcs,qpcr,0,0,NA,0,negative,ParkinsonsPatients.Controls,PBMC bp,positive,0,meanssd,0,NA,NA,NA,NA,1.402514596,4498,4071,NA,NA,267.2,331.5,43,53,NA,NA,NA,NA,NA,,0.572053564,0.004764199
274,643,m,humphreys2012,humphreys,2012,Telomere shortening in formerly abused and never abused women,homo sapiens,Intimate partner violence,psychosocial,traumatic experience,more adversity,32.1 ± 9.3 years,11716.5,"4,745",adult,44712.5,1752,"Opportunity sample of women, some abused, USA",0,NA,0,NA,11716.5,adult,1,adultadult,102,0,female,102,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Abused (intimate partner violence) vs. never,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.475830951,1.39,1.51,NA,NA,0.26,0.24,61,41,NA,NA,NA,NA,NA,,-0.227196163,0.00890523
275,547,m,huzen2010,huzen,2010,Telomere length and psychological well-being in patients with chronic heart failure,homo sapiens,Mental health score (RAND-36 questionnaire),psychiatric,other,none,73 years,26645,4927.5,adult,44712.5,unreported,COACH (Coordinating study evaluating Outcomes of Advising and Counseling in Heart failure) study patients with heart failure,0,NA,0,NA,26645,adult,1,adultadult,347,543,both,890,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Perceived mental health RAND-36 score (higher is better),Log transformed T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.11,NA,NA,NA,"This study actually has other predictors in it that did not come out significant, and for these ones they did not report enough stats to include them, hence biased reporting",0.16,0.001068004
276,639,m,jergovic2014,jergovic,2014,Telomere shortening and immune activity in war veterans with posttraumatic stress disorder,homo sapiens,Post-traumatic stress disorder,psychiatric,PTSD,none,46.5 years,16972.5,"5,110",adult,44712.5,unreported,War veterans with PTSD and healthy controls from Croatia,0,NA,0,NA,16972.5,adult,1,adultadult,0,47,male,45,wholeblood,wbcs,qpcr,0,0,NA,1,negative,War veteran with PTSD vs. healthy control,T/S ratio,negative,0,meansse,1,NA,NA,NA,NA,-1.024598038,0.86,1.03,0.031,0.041,0.164036581,0.169047331,28,17,NA,NA,NA,NA,NA,,-0.444888979,0.014620963
277,640,m,jergovic2014,jergovic,2014,Telomere shortening and immune activity in war veterans with posttraumatic stress disorder,homo sapiens,Smoking,smoking,none,none,46.5 years,16972.5,"5,110",adult,44712.5,unreported,War veterans with PTSD from Croatia,0,NA,0,NA,16972.5,adult,1,adultadult,0,28,male,28,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Smoker vs. non-smoker,T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-2.182926829,NA,NA,NA,NA,NA,NA,17,11,NA,NA,-0.358,NA,0.164,,-0.729358983,0.00811323
278,641,m,jergovic2014,jergovic,2014,Telomere shortening and immune activity in war veterans with posttraumatic stress disorder,homo sapiens,Taking mood stabilizers,medicaltreatment,none,none,46.5 years,16972.5,"5,110",adult,44712.5,unreported,War veterans with PTSD from Croatia,0,NA,0,NA,16972.5,adult,1,adultadult,0,28,male,28,wholeblood,wbcs,qpcr,0,0,NA,1,none,Taking mood stabilizers,T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-2.298780488,NA,NA,NA,NA,NA,NA,7,21,NA,NA,-0.377,NA,0.164,,-0.705475221,0.009344816
279,391,m,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Maternal smoking in pregnancy,smoking,none,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,embryonicadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Maternal smoking in pregnancy,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.02,NA,NA,NA,,-0.02,0.001478107
280,392,m,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Abuse/violence total score,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,childadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Abuse violence score,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.05,NA,NA,NA,,0.1,0.001449852
281,393,ss392,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Childhood sexual abuse ,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,childadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood sexual abuse ,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.06,NA,NA,NA,,0.11,0.001443708
282,394,ss392,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Childhood physical abuse,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,childadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood physical abuse,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.03,NA,NA,NA,,0.08,0.001460416
283,395,ss392,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Parental care (Parental Bonding Instrument),parentalcare,more parental care,none,0-16 years,2920,4927.5,child,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,childadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Parental care,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.06,NA,NA,NA,,-0.06,0.001468658
284,396,ss392,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Inter-parental violence/conflict (Conflict tactics scale),parentalcare,less parental care,none,0-16 years,2920,4927.5,child,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,0,childadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Inter-parental violence/conflict ,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001478994
285,397,m,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Total substance use disorders,other,other,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Total substance use disorders,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,,0.07,0.001464828
286,398,ss397,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Nicotine dependence,smoking,none,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Nicotine dependence,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.01,NA,NA,NA,,0.06,0.001468658
287,399,ss397,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Alcohol dependence,alcohol,more alcohol,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Alcohol dependence,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.01,NA,NA,NA,,0.06,0.001468658
288,400,ss397,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Cannabis dependence,other,other,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cannabis dependence,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,,0.07,0.001464828
289,401,ss397,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Other drug dependence,other,other,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Other drug dependence,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,,0.07,0.001464828
290,402,m,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Total mental health problems,psychiatric,other,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Total mental health problems,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.03,NA,NA,NA,,0.08,0.001460416
291,403,ss402,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Major depression,psychiatric,depression and anxiety,depression,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Major depression,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.03,NA,NA,NA,,0.08,0.001460416
292,404,ss402,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,DSM-IV Anxiety disorder,psychiatric,depression and anxiety,anxiety,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Anxiety disorder,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,,0.07,0.001464828
293,405,ss402,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Suicidal ideation/attempt,psychiatric,other,none,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Suicidal ideation/attempt,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001478994
294,406,ss402,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Lifetime trauma,psychosocial,traumatic experience,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Lifetime trauma,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001478994
295,407,m,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Total adult life events exposure (ages 16-25),psychosocial,other negative,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Total adult life events exposure (ages 16-25),LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.02,NA,NA,NA,,-0.02,0.001478107
296,408,ss407,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Employment problems ,socioeconomic,occupation or employment status,lower,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Employment problems ,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.02,NA,NA,NA,,-0.02,0.001478107
297,409,ss407,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Serious illness/accident for self/others,psychosocial,traumatic experience,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Serious illness/accident for self/others,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001478994
298,410,ss407,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Serious relationship problems,psychosocial,social network,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Serious relationship problems,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.01,NA,NA,NA,,0.06,0.001468658
299,411,ss407,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Victimisation problems,psychosocial,other negative,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Victimisation problems,LTL (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.001478994
300,412,ss407,jodczyk2014,jodczyk,2014,No Association between Mean Telomere Length and Life Stress Observed in a 30 Year Birth Cohort,homo sapiens,Pregnancy/parenthood stressors,psychosocial,stress,more adversity,16-25 years,7482.5,4927.5,adult,44712.5,unreported,"677 cohort members (86% white, 14% NZ Maori/Pacific Island ethnicity) of the Christchurch Health and Development Study (CHDS).",0,NA,0,NA,10585,adult,1,adultadult,unreported,unreported,both,677,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Pregnancy/parenthood stressors,LTL (T/S ratio),positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.04,NA,NA,NA,,0.09,0.001455423
301,631,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Tobacco farmer exposure to pesticides,environmentalhazard,none,none,41.5 years,15147.5,"5,110",adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,0,60,male,60,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Being a pesticide-exposed tobacco farmer vs. control,T/S ratio converted to kp/genome,negative,0,meanssd,1,NA,NA,NA,NA,-1.345063618,30.4,52.6,NA,NA,12.4,21.6,37,23,NA,NA,NA,NA,NA,,-0.547320671,0.008315531
302,632,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Tobacco farmer exposure to pesticides,environmentalhazard,none,none,41.5 years,15147.5,"4,745",adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,0,female,64,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Being a pesticide-exposed tobacco farmer vs. control,T/S ratio converted to kp/genome,negative,0,meanssd,1,NA,NA,NA,NA,-0.553415589,34.7,43.7,NA,NA,12.6,18.2,25,39,NA,NA,NA,NA,NA,,-0.260671423,0.013789174
303,633,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Smoking ex vs. never,smoking,none,none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,107,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Smoking ex vs. never,T/S ratio converted to kp/genome,negative,0,meanssd,1,NA,NA,NA,NA,-0.443834356,34.66,42.27,NA,NA,13.02,17.93,20,87,NA,NA,NA,NA,NA,,-0.170492866,0.008893484
304,634,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Smoking current vs. never,smoking,none,none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,104,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Smoking current vs. never,T/S ratio converted to kp/genome,negative,0,meanssd,1,NA,NA,NA,NA,-0.63181387,31.41,42.27,NA,NA,12.47,17.93,17,87,NA,NA,NA,NA,NA,,-0.227509188,0.008729692
305,635,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Drinker vs. non-drinker,alcohol,more alcohol,none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,124,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Drinker vs. non-drinker,T/S ratio converted to kp/genome,positive,0,meanssd,1,NA,NA,NA,NA,0.334365305,40.893,35.355,NA,NA,16.88,15.45,95,29,NA,NA,NA,NA,NA,,0.140137208,0.007813893
306,636,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Fruit and vegetable intake: Daily vs.1-2 days per week,nutrition,"fruit, legumes and vegetables",none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,77,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Fruit and vegetable intake: 1-2 days per week vs. daily ,T/S ratio converted to kp/genome,positive,0,meanssd,1,NA,NA,NA,NA,0.005302474,41.24,41.14,NA,NA,15.6,19.65,17,60,NA,NA,NA,NA,NA,,0.002199312,0.013157767
307,637,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Fruit and vegetable intake: Daily vs.1-2 days per week,nutrition,"fruit, legumes and vegetables",none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,77,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Fruit and vegetable intake: 3-4 days per week vs. daily ,T/S ratio converted to kp/genome,positive,0,meanssd,1,NA,NA,NA,NA,-0.0272031,40.64,41.14,NA,NA,12.64,19.65,17,60,NA,NA,NA,NA,NA,,-0.011282364,0.013154545
308,638,m,kahl2016,kahl,2016,Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields,homo sapiens,Fruit and vegetable intake: 5-6 vs.1-2 days per week,nutrition,"fruit, legumes and vegetables",none,41.5 years,15147.5,4927.5,adult,44712.5,7685,Tobacco farmers from Brazil,0,NA,0,NA,15147.5,adult,1,adultadult,64,60,both,87,wholeblood,wbcs,qpcr,0,0,NA,unreported,negative,Fruit and vegetable intake: 5-6 vs.1-2 days per week,T/S ratio converted to kp/genome,positive,0,meanssd,1,NA,NA,NA,NA,-0.362902527,34.63,41.14,NA,NA,13.26,19.65,27,60,NA,NA,NA,NA,NA,,-0.16557398,0.010999094
309,177,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Years of living in area (proxy for urbanisation stress),psychosocial,other negative,more adversity,"Mean age = 48.5, minus mean years in area (30.5) = 17.5",12045,4927.5,adult,44712.5,NA,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Years of living in area (proxy for urbanisation stress),LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.16,NA,NA,NA,NA,"The IV was length of exposure, so the ""LengthExposure"" variable was recorded as ""NA""",-0.16,0.002792516
310,178,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,HIV infection status,disease,HIV & AIDS,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,1,negative,HIV infection status,LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.23,NA,NA,NA,NA,,-0.23,0.002638231
311,179,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Hypertension,disease,cardiovascular,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Hypertension,LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,NA,,-0.13,0.002842605
312,180,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Alcohol abuse,alcohol,more alcohol,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Alcohol abuse,LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.22,NA,NA,NA,NA,,-0.22,0.00266336
313,181,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Smoking status,smoking,none,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking status,LTL T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.04,NA,NA,NA,NA,,0.04,0.002931772
314,182,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Physical activity - energy expenditure (kcal/d),physicalactivity,more activity,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,7,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Physical activity - energy expenditure (kcal/d),LTL T/S ratio,positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,NA,,0.02,0.002938824
315,183,ss184,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,"Moderate depression (>10 score on Patient Health Questionnaire, 9 items, score range 0-27)",psychiatric,depression and anxiety,depression,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Moderate depression (>10 score on Patient Health Questionnaire, 9 items, score range 0-27)",LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.06,NA,NA,NA,NA,,-0.06,0.002920038
316,184,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,Depressive symptoms (Patient Health Questionnaire score),psychiatric,depression and anxiety,depression,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Depressive symptoms (Patient Health Questionnaire score),LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.11,NA,NA,NA,NA,,-0.11,0.002870431
317,185,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,"Symptoms of distress (General Health Questionnaire, 28-item)",psychiatric,other,none,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Symptoms of distress (General Health Questionnaire, 28-item)",LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.08,NA,NA,NA,NA,,-0.08,0.00290365
318,186,m,kanel2015,kanel,2015,Comparison of telomere length in black and white teachers from south africa: The sympathetic activity and ambulatory blood pressure in africans study,homo sapiens,"Perceived work stress (Teacher Stress Inventory, 20-item, score range 20-100)",psychosocial,work-related stress,more adversity,Mean age = 48.5,17702.5,4927.5,adult,44712.5,unreported,161 black South African teachers and 180 white South African teachers aged 23 to 66 years without a history of atherothrombotic vascular disease.,0,NA,0,NA,17702.5,adult,1,adultadult,168,173,both,341,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Perceived work stress (Teacher Stress Inventory, 20-item, score range 20-100)",LTL T/S ratio,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,NA,,-0.07,0.002912424
319,644,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (past) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,72,CD4+ cells,wbcs,qfish,0,0,NA,1,negative,Depression (past) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-0.797086812,55.06,67.77,NA,NA,15.73,16.05,24,48,NA,NA,NA,NA,NA,,-0.35173915,0.010815012
320,645,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (current) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,68,CD4+ cells,wbcs,qfish,0,0,NA,1,negative,Depression (current) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-0.884469855,53.09,67.77,NA,NA,17.88,16.05,20,48,NA,NA,NA,NA,NA,,-0.373791655,0.01104599
321,646,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (past) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,69,CD8+ T-cells,wbcs,qfish,0,0,NA,1,negative,Depression (past) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-1.340634113,51.1,68.7,NA,NA,11.98,13.69,24,45,NA,NA,NA,NA,NA,,-0.538167189,0.007421091
322,647,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (current) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,62,CD8+ T-cells,wbcs,qfish,0,0,NA,1,negative,Depression (current) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-1.47404032,48.76,68.7,NA,NA,13.07,13.69,17,45,NA,NA,NA,NA,NA,,-0.549432772,0.00798978
323,648,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (past) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,67,CD20+ B-cells,wbcs,qfish,0,0,NA,1,negative,Depression (past) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-1.450239259,47.44,68.83,NA,NA,9.44,16.83,23,44,NA,NA,NA,NA,NA,,-0.567133319,0.006972303
324,649,m,karabatsiakis2014,karabatsiakis,2014,Telomere shortening in leukocyte subpopulations in depression,homo sapiens,Depression (current) versus never,psychiatric,depression and anxiety,depression,Around 52.2 years,19053,"4,745",adult,44712.5,6865.318182,44 females with history of depression plus 50 healthy controls,0,NA,0,NA,19053,adult,1,adultadult,94,0,female,60,CD20+ B-cells,wbcs,qfish,0,0,NA,1,negative,Depression (current) versus never,Mean TL as a percentage of a reference sample,negative,0,meanssd,1,NA,NA,NA,NA,-1.171250591,50,68.83,NA,NA,13.69,16.83,16,44,NA,NA,NA,NA,NA,,-0.459916813,0.010537207
325,216,m,kiefer2008,kiefer,2008,Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women,homo sapiens,Smoking,smoking,none,none,Mean age = 49.31,17998.15,"4,745",adult,44712.5,unreported,56 women (combined sample from those described below),0,NA,0,NA,17998.15,adult,1,adultadult,56,0,female,56,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smokers.Non-smokers,LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.02,NA,NA,NA,,-0.02,0.018167276
326,217,m,kiefer2008,kiefer,2008,Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women,homo sapiens,Restrained eating - restraint subscale of the Dutch Eating Behavior Questionnaire (DEBQ),other,other,none,Mean age = 49.31,17998.15,"4,745",adult,44712.5,unreported,56 women (combined sample from those described below),0,NA,0,NA,17998.15,adult,1,adultadult,56,0,female,56,leukocytes,wbcs,qpcr,0,0,NA,1,none,Dietary restriction score,LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.26,NA,NA,NA,,-0.26,0.015806723
327,218,sg216,kiefer2008,kiefer,2008,Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women,homo sapiens,Smoking in premenopausal women,smoking,none,none,Mean age = 38.89,14117.07,"4,745",adult,44712.5,unreported,"36 premenopausal women (ages 20-50). Of these women, three were current smokers. Twenty-seven were caring for a disabled child (caregivers), and nine were age-matched controls.",0,NA,0,NA,14117.07,adult,1,adultadult,36,0,female,36,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smokers.Non-smokers,LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.06,NA,NA,NA,NA,,-0.06,0.028366085
328,219,sg217,kiefer2008,kiefer,2008,Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women,homo sapiens,Restrained eating in premenopausal women - restraint subscale of the Dutch Eating Behavior Questionnaire (DEBQ),other,other,none,Mean age = 38.89,14117.07,"4,745",adult,44712.5,unreported,"36 premenopausal women (ages 20-50). Of these women, three were current smokers. Twenty-seven were caring for a disabled child (caregivers), and nine were age-matched controls.",0,NA,0,NA,14117.07,adult,1,adultadult,36,0,female,36,leukocytes,wbcs,qpcr,0,0,NA,1,none,Dietary restriction score,LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.38,NA,NA,NA,NA,,-0.38,0.020915753
329,220,sg217,kiefer2008,kiefer,2008,Dietary Restraint and Telomere Length in Pre- and Postmenopausal Women,homo sapiens,Restrained eating in postmenopausal women - restraint subscale of the Dutch Eating Behavior Questionnaire (DEBQ),other,other,none,Mean age = 59.73,21801.45,"4,745",adult,44712.5,unreported,"20 healthy postmenopausal women (ages 52-79), 13 of whom were caring for a family member with some type of dementia (caregivers), and 7 age-matched controls.",0,NA,0,NA,21801.45,adult,1,adultadult,20,0,female,20,leukocytes,wbcs,qpcr,0,0,NA,1,none,Dietary restriction score,Log-transformed LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.55,NA,NA,NA,NA,,-0.55,0.025605592
330,464,m,kim2009,kim,2009,Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs,homo sapiens,Degeneration of the nucleus pulposus (grade III vs grade II),disease,other,none,Mean age = 37.84,13811.6,4927.5,adult,44712.5,unreported,Twenty-five patients (14 female and 11 male) who underwent open discectomy for symptomatic herniated nucleus pulposus.,0,NA,0,NA,13811.6,adult,1,adultadult,unreported,unreported,both,20,nucleus pulposus,wbcs,southernblot,0,0,NA,0,negative,GradeIIINucleusPulposusDegereration.GradeIINucleusPulposusDegereration,Nucleus pulposus TRF (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.062060048,14.59,14.9,NA,NA,5.16,3.4,17,3,NA,NA,NA,NA,NA,,-0.022154431,0.052579926
331,465,m,kim2009,kim,2009,Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs,homo sapiens,Degeneration of the nucleus pulposus (grade IV vs grade II),disease,other,none,Mean age = 44.765,16339.225,4927.5,adult,44712.5,unreported,Twenty-five patients (14 female and 11 male) who underwent open discectomy for symptomatic herniated nucleus pulposus.,0,NA,0,NA,16339.225,adult,1,adultadult,unreported,unreported,both,8,nucleus pulposus,wbcs,southernblot,0,0,NA,0,negative,GradeIVNucleusPulposusDegereration.GradeIINucleusPulposusDegereration,Nucleus pulposus TRF (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.171234314,13.58,14.9,NA,NA,9.13,3.4,5,3,NA,NA,NA,NA,NA,,-0.08261507,0.140913726
332,356,m,kim2010,kim,2010,Leukocyte Telomere Length and Plasma Catestatin and Myeloid-Related Protein 8/14 Concentrations in Children With Obstructive Sleep Apnea,homo sapiens,Sleep apnea - measured by apnea-hypopnea index (AHI),disease,sleep apnea,none,Mean age = 7.7,2810.5,4927.5,child,44712.5,unreported,"111 children with sleep apnea, and 102 controls, between the ages of 5 and 10 years",0,NA,0,NA,2810.5,child,1,childchild,89,124,both,213,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Sleep apnea index,LTL (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.236,NA,NA,NA,NA,,0.236,0.004206179
333,357,m,kim2015,kim,2015,Antioxidants safeguard telomeres in bold chicks,larus michahellis,Vitamin supplementation,nutrition,vitamins,,0-7 days ,3.5,unavailable,juvenile,7008,7,Gulls from Spain,0,NA,NA,NA,7,juvenile,1,juvenilejuvenile,unreported,unreported,both,212,rbcs,rbcs,qpcr,1,0,reduce,0,positive,Antioxidant vitamin supplementation.Control,RBC T/S ratio,positive,1,fanova,1,0.5,196,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,"This effect was extracted from a table in a supplement. It is coded as positive because the sign of the model coefficient is positive. However, the direction is not confirmed in the text.  ",0.050443327,0.004715248
334,519,m,kotrschal2007,kotrschal,2007,Stress impacts telomere dynamics,mus musculus,Reproduction and crowding,other,other,,"Starting at four weeks of age, until six months of age",105,42,adult,1460,150,Offspring of wild-caught mice,0,NA,NA,84,150,adult,1,adultadult,27,0,female,27,leukocytes,wbcs,qpcr,1,1,Induce,1,negative,Treatment group (REP + CRD vs. CONTROL),Change in T/S,negative,0,ttest,1,NA,NA,2.86,26,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.489195603,0.022255605
335,520,m,kotrschal2007,kotrschal,2007,Stress impacts telomere dynamics,mus musculus,Crowding,other,other,,"Starting at four weeks of age, until six months of age",105,42,adult,1460,150,Offspring of wild-caught mice,0,NA,NA,84,150,adult,1,adultadult,0,18,male,18,leukocytes,wbcs,qpcr,1,1,Induce,1,negative,Treatment group (CRD vs. REP),Change in T/S,negative,0,ttest,1,NA,NA,1.83,17,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.40567722,0.041055094
336,521,m,krishna2015,krishna,2015,Association of leukocyte telomere length with oxidative stress in yoga practitioners,homo sapiens,Yoga practitioner status,psychosocial,other positive,less adversity,30-40 years,12775,4927.5,adult,44712.5,unreported,Healthy Yoga practitioners within the age group of 30-40 y with no medical conditions and at least two years of Yoga practice,0,NA,0,NA,12775,adult,1,adultadult,unreported,unreported,both,33,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Yogis.Non-yogis,LTL T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,-5.738662677,1.41,1.69,NA,NA,0.06,0.03,18,15,NA,NA,NA,NA,NA,,-0.943869428,0.000372034
337,612,m,kume2012,kume,2012,Telomere length shortening in patients with dementia with Lewy bodies,homo sapiens,Dementia with Lewy bodies,disease,other,none,79.75 years,29108.75,4927.5,adult,44712.5,949,Patients with dementia with Lewy bodies and elderly non-demented controls,0,NA,0,NA,29108.75,adult,1,adultadult,37,31,both,68,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Dementia with Lewy bodies vs. control,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.609729334,0.705,0.793,NA,NA,0.159,0.129,33,35,NA,NA,NA,NA,NA,,-0.291498613,0.012496676
338,659,m,kwon2015,kwon,2015,The association between leukocyte telomere lengths and sleep instability based on cardiopulmonary coupling analysis,homo sapiens,Obstructive sleep apnea symptoms,disease,sleep apnea,none,58.9 ± 7.1 years,21498.5,4927.5,adult,44712.5,unreported,Participants in Korean Genome and Epidemiology Study (KoGES),0,NA,0,NA,21498.5,adult,1,adultadult,243,138,both,344,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,"Apnea-Hypopnea index, score of 5-14 vs. <5",Leucocyte T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.05,1.13,1.15,NA,NA,0.4,0.4,119,225,NA,NA,NA,NA,NA,,-0.023776806,0.002912156
339,660,m,kwon2015,kwon,2015,The association between leukocyte telomere lengths and sleep instability based on cardiopulmonary coupling analysis,homo sapiens,Obstructive sleep apnea symptoms,disease,sleep apnea,none,58.9 ± 7.1 years,21498.5,4927.5,adult,44712.5,unreported,Participants in Korean Genome and Epidemiology Study (KoGES),0,NA,0,NA,21498.5,adult,1,adultadult,243,138,both,262,leukocytes,wbcs,qpcr,0,0,NA,unreported,negative,"Apnea-Hypopnea index, score of 15 or more vs. <5",Leucocyte T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.1,1.11,1.15,NA,NA,0.4,0.4,37,225,NA,NA,NA,NA,NA,,-0.034803878,0.003822141
340,446,m,ladwig2013,ladwig,2013,"Posttraumatic Stress Disorder and Not Depression Is Associated with Shorter Leukocyte Telomere Length: Findings from 3,000 Participants in the Population-Based KORA F4 Study",homo sapiens,PTSD status (no PTSD vs partial PTSD),psychiatric,PTSD,none,Mean age = 54.5,19892.5,4927.5,adult,44712.5,unreported,"3,000 individuals (1,449 men and 1,551 women) from the population-based KORA F4 study (2006–2008), located in southern Germany",0,NA,0,NA,19892.5,adult,1,adultadult,1519,1430,both,2949,leukocytes,wbcs,qpcr,0,0,NA,0,negative,NoPTSD.PartialPTSD,LTL (T/S ratio),positive,0,meanssd,0,NA,NA,NA,NA,0,1.85,1.85,NA,NA,0.29,0.33,262,2687,NA,NA,NA,NA,NA,,0,0.000339213
341,447,m,ladwig2013,ladwig,2013,"Posttraumatic Stress Disorder and Not Depression Is Associated with Shorter Leukocyte Telomere Length: Findings from 3,000 Participants in the Population-Based KORA F4 Study",homo sapiens,PTSD status (no PTSD vs full PTSD),psychiatric,PTSD,none,Mean age = 55.5,20257.5,4927.5,adult,44712.5,unreported,"3,000 individuals (1,449 men and 1,551 women) from the population-based KORA F4 study (2006–2008), located in southern Germany",0,NA,0,NA,20257.5,adult,1,adultadult,1389,1349,both,2738,leukocytes,wbcs,qpcr,0,0,NA,0,negative,NoPTSD.FullPTSD,LTL (T/S ratio),negative,0,meanssd,0,NA,NA,NA,NA,-0.212563994,1.78,1.85,NA,NA,0.29,0.33,51,2687,NA,NA,NA,NA,NA,,-0.028727372,0.000364761
342,601,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,Education (high school or less vs. beyond high school),socioeconomic,education,lower,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Education (high school or less vs. beyond high school),T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,0.25,1.02,0.94,NA,NA,0.32,0.32,123,160,NA,NA,NA,NA,NA,,0.122986245,0.003439637
343,602,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,Has no partner versus has one,psychosocial,social network,more adversity,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Has no partner versus has one,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.118879438,0.96,1,NA,NA,0.34,0.33,182,101,NA,NA,NA,NA,NA,,-0.056860867,0.003523206
344,603,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,Low income (having <$1000/mo versus more),socioeconomic,income,lower,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Income <$1000/mo versus more,T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.031926211,0.98,0.97,NA,NA,0.3,0.34,193,90,NA,NA,NA,NA,NA,,0.014866641,0.003544532
345,604,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,AIDS diagnosis yes/no,disease,HIV & AIDS,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,negative,AIDS diagnosis yes/no,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.093631467,0.96,0.99,NA,NA,0.33,0.31,145,138,NA,NA,NA,NA,NA,,-0.046750238,0.003530616
346,605,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,Health problems other than HIV yes/no,disease,other,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,264,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Health problems other than HIV yes/no,T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0,0.98,0.98,NA,NA,0.32,0.31,103,161,NA,NA,NA,NA,NA,,0,0.003802281
347,606,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,High tension-anxiety (vs. low),psychiatric,depression and anxiety,anxiety,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,275,leukocytes,wbcs,qpcr,0,0,NA,0,negative,High tension-anxiety vs. low,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,0.062764478,0.99,0.97,NA,NA,0.33,0.31,117,158,NA,NA,NA,NA,NA,,0.031016565,0.003642616
348,607,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,High depressive symptoms (versus low),psychiatric,depression and anxiety,depression,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,281,leukocytes,wbcs,qpcr,0,0,NA,0,negative,High depressive symptoms versus low,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.031754679,0.97,0.98,NA,NA,0.32,0.31,137,144,NA,NA,NA,NA,NA,,-0.015870413,0.00356963
349,608,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,"Total sleep time, actigraphy",sleep,more sleep,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Total sleep time, actigraphy",T/S ratio,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.115,NA,NA,NA,NA,,0.115,0.003452925
350,609,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,"Total sleep time, self-report",sleep,more sleep,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Total sleep time, self-report",T/S ratio,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.102,NA,NA,NA,NA,,0.102,0.003472696
351,610,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,Sleep quality (actigraphy - time spent awake after first going to sleep),sleep,more sleep,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Sleep quality (actigraphy - time spent awake after first going to sleep),T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.104,NA,NA,NA,NA,,-0.104,0.003469805
352,611,m,lee2014,lee,2014,Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus,homo sapiens,"Sleep quality, PQSI total score  [higher is worse]",sleep,less sleep,none,44.9 years (8.4),16388.5,4927.5,adult,44712.5,unreported,HIV patients from San Fransisco,0,NA,0,NA,16388.5,adult,1,adultadult,73,210,both,283,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Sleep quality, PQSI total score  [higher is worse]",T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,NA,,-0.07,0.003511433
353,486,m,lewin 2015,lewin ,2015,Socioecological variables predict telomere length in wild spotted hyenas,crocuta crocuta,Dominance rank,socioeconomic,relative status,,2.5-13 years,2828.75,867,adult,15001.5,unreported,"54 adult hyenas who were members of five social groups (clans) sampled between 1999 and 2013 in the Masai Mara National Reserve, Kenya",0,NA,NA,NA,2828.75,adult,1,adultadult,unreported,unreported,both,54,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Dominance rank,LTL TRF (kb),positive,1,fanova,1,8.43,34.9,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.441082109,0.012240456
354,350,m,liu2014,liu,2014,Leucocyte Telomere Shortening in relation to Newly Diagnosed Type 2 Diabetic Patients with Depression,homo sapiens,Type 2 diabetes status,disease,diabetes,none,Mean age = 52.91,19312.15,4927.5,adult,44712.5,unreported,"71 patients with newly diagnosed type 2 diabetes (T2D) (male 40/female 31)  recruited from the Division of Endocrinology, Tongji Hospital, Tongji Medical College, China + 52 subjects with normal glycemic level enrolled as control group (Ctrl group) (male 30/female 22).",0,NA,0,NA,19312.15,adult,1,adultadult,53,70,both,123,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Type2Diabetes.Controls,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.687719296,2.01,2.28,NA,NA,0.47,0.25,71,52,NA,NA,NA,NA,NA,,-0.321675587,0.00658817
355,351,m,liu2014,liu,2014,Leucocyte Telomere Shortening in relation to Newly Diagnosed Type 2 Diabetic Patients with Depression,homo sapiens,Depression score (HADS-D),psychiatric,depression and anxiety,depression,Mean age = 52.91,19312.15,4927.5,adult,44712.5,unreported,"71 patients with newly diagnosed type 2 diabetes (T2D) (male 40/female 31)  recruited from the Division of Endocrinology, Tongji Hospital, Tongji Medical College, China + 52 subjects with normal glycemic level enrolled as control group (Ctrl group) (male 30/female 22).",0,NA,0,NA,19312.15,adult,1,adultadult,53,70,both,123,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Depression score,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.621,NA,NA,NA,NA,,-0.621,0.003093746
356,736,m,ma2013,ma,2013,Association between oxidative stress and telomere length in type 1 and type 2 diabetic patients,homo sapiens,Type 1 diabetes status,disease,diabetes,none,Mean age = 28.79 years,10508.35,4927.5,adult,44712.5,1095,"62 Chinese Han T2D patients, 34 T1D patients, and 40 non-diabetic subjects used as control.",0,NA,0,NA,10508.35,adult,1,adultadult,32,42,both,74,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Type1Diabetes.Controls,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-1.174972837,1.77,2.39,NA,NA,0.5,0.55,34,40,NA,NA,NA,NA,NA,,-0.505298916,0.007596409
357,737,m,ma2013,ma,2013,Association between oxidative stress and telomere length in type 1 and type 2 diabetic patients,homo sapiens,Type 2 diabetes status,disease,diabetes,none,Mean age = 41.2 years,15038,4927.5,adult,44712.5,1825,"62 Chinese Han T2D patients, 34 T1D patients, and 40 non-diabetic subjects used as control.",0,NA,0,NA,15038,adult,1,adultadult,46,56,both,102,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Type2Diabetes.Controls,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-1.384423401,1.67,2.39,NA,NA,0.5,0.55,62,40,NA,NA,NA,NA,NA,,-0.559995761,0.004664866
358,346,m,malan2011,malan,2011,Investigation of telomere length and psychological stress in rape victims,homo sapiens,Resilience scores in rape victims at baseline (measured within 2 weeks of rape using Connor–Davidson Resilience Scale),other,other,none,Median age = 22.3,8139.5,"4,745",adult,44712.5,unreported,64 female rape survivors (19% black; 1% white; 80% mixed ancestry) from three independent rape cohorts recruited from two rape centers in the Cape Town area.,0,NA,0,NA,8139.5,adult,1,adultadult,64,0,female,64,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Resilience to trauma,LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.1,NA,NA,NA,NA,,0.1,0.015557143
359,347,ss346,malan2011,malan,2011,Investigation of telomere length and psychological stress in rape victims,homo sapiens,Resilience scores in rape victims at 3-month follow-up using Connor–Davidson Resilience Scale,other,other,none,Median age = 22.3,8139.5,"4,745",adult,44712.5,unreported,64 female rape survivors (19% black; 1% white; 80% mixed ancestry) from three independent rape cohorts recruited from two rape centers in the Cape Town area.,0,NA,0,NA,8139.5,adult,1,adultadult,64,0,female,64,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Resilience to trauma,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.03,NA,NA,NA,NA,,-0.03,0.015844457
360,348,ss346,malan2011,malan,2011,Investigation of telomere length and psychological stress in rape victims,homo sapiens,Change in resilience scores in rape victims (between baseline and 3-month follow-up using Connor–Davidson Resilience Scale),other,other,none,Median age = 22.3,8139.5,"4,745",adult,44712.5,unreported,64 female rape survivors (19% black; 1% white; 80% mixed ancestry) from three independent rape cohorts recruited from two rape centers in the Cape Town area.,0,NA,0,NA,8139.5,adult,1,adultadult,64,0,female,64,leukocytes,wbcs,qpcr,0,0,NA,0,none,Change in resilience to trauma,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,NA,,-0.07,0.015717841
361,349,m,malan2011,malan,2011,Investigation of telomere length and psychological stress in rape victims,homo sapiens,PTSD diagnosis in rape victims,psychiatric,PTSD,none,Median age = 22.3,8139.5,"4,745",adult,44712.5,unreported,64 female rape survivors (19% black; 1% white; 80% mixed ancestry) from three independent rape cohorts recruited from two rape centers in the Cape Town area.,0,NA,0,NA,8139.5,adult,1,adultadult,62,0,female,62,leukocytes,wbcs,qpcr,0,0,NA,1,negative,PTSD status,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.641158361,0.76,0.91,NA,NA,0.19,0.24,9,53,NA,NA,NA,NA,NA,,-0.220307426,0.014840737
362,480,m,malan-muller2013,malan-muller,2013,Shorter Telomere Length - A Potential Susceptibility Factor for HIV-Associated Neurocognitive Impairments in South African Woman,homo sapiens,HIV infection status (HIV negative vs HIV positive),disease,HIV & AIDS,none,Mean age = 29.8,10877,"4,745",adult,44712.5,unreported,"128 South African women, 83 of whom were HIV-positive.",0,NA,0,NA,10877,adult,1,adultadult,128,0,female,128,leukocytes,wbcs,qpcr,0,0,NA,1,negative,HIVPositive.HIVNegative,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-1.38576887,0.61,0.98,NA,NA,0.2,0.36,83,45,NA,NA,NA,NA,NA,,-0.551798443,0.003809023
363,481,m,malan-muller2013,malan-muller,2013,Shorter Telomere Length - A Potential Susceptibility Factor for HIV-Associated Neurocognitive Impairments in South African Woman,homo sapiens,Childhood trauma (Yes = CTQ-SF score under 40 vs No = CTQ-SF score of 41+),psychosocial,traumatic experience,more adversity,Mean age = 29.8,10877,"4,745",adult,44712.5,unreported,"128 South African women, 83 of whom were HIV-positive.",0,NA,0,NA,10877,adult,1,adultadult,128,0,female,128,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ChildhoodTrauma.NoChildhoodTrauma,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.249044445,0.7,0.78,NA,NA,0.28,0.36,66,62,NA,NA,NA,NA,NA,,-0.123508469,0.007635622
364,281,m,mansour2011,mansour,2011,Does telomere length mediate associations between inbreeding and increased risk for bipolar I disorder and schizophrenia?,homo sapiens,Cosanguinity,other,other,none,Mean age = 26.88,9811.2,4927.5,adult,44712.5,unreported,"Outpatients attending the MUH Psychiatry outpatient clinics who received a clinical diagnosis of BP1, SZ or SZA (DSM IV criteria). Controls were unaffected, unrelated adults who resided in the same geographic area.",0,NA,0,NA,9811.2,adult,1,adultadult,146,196,both,342,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Inbreeding coefficient,LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.026,NA,NA,NA,NA,,-0.026,0.002928588
365,282,m,mansour2011,mansour,2011,Does telomere length mediate associations between inbreeding and increased risk for bipolar I disorder and schizophrenia?,homo sapiens,Bipolar disorder,psychiatric,depression and anxiety,depression,Mean age = 26.18,9555.7,4927.5,adult,44712.5,unreported,"Outpatients attending the MUH Psychiatry outpatient clinics who received a clinical diagnosis of BP1, SZ or SZA (DSM IV criteria). Controls were unaffected, unrelated adults who resided in the same geographic area.",0,NA,0,NA,9555.7,adult,1,adultadult,104,118,both,222,leukocytes,wbcs,qpcr,0,0,NA,0,negative,BipolarPatients.Controls,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.05,0.95,0.97,NA,NA,0.4,0.4,108,114,NA,NA,NA,NA,NA,,-0.024983067,0.00451924
366,283,m,mansour2011,mansour,2011,Does telomere length mediate associations between inbreeding and increased risk for bipolar I disorder and schizophrenia?,homo sapiens,Schizophrenia ,psychiatric,schizophrenia,none,Mean age = 27.59,10070.35,4927.5,adult,44712.5,unreported,"Outpatients attending the MUH Psychiatry outpatient clinics who received a clinical diagnosis of BP1, SZ or SZA (DSM IV criteria). Controls were unaffected, unrelated adults who resided in the same geographic area.",0,NA,0,NA,10070.35,adult,1,adultadult,42,78,both,120,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SchizophreniaPatients.Controls,LTL T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.07124705,0.89,0.87,NA,NA,0.3,0.26,60,60,NA,NA,NA,NA,NA,,0.035600943,0.008382074
367,448,m,marchetto2016,marchetto,2016,Prenatal stress and newborn telomere length,homo sapiens,"Maternal stress during pregnancy (high, ?300 vs low, ?299) effect on newborn cordblood TL - measured with Holmes and Rahe Stress Scale questionnaire (also referred to as the Social Readjustment Rating Scale)",psychosocial,other negative,more adversity,embryonic,embryonic,4927.5,embryonic,44712.5,280,Prospective cohort study of 24 mother-newborn dyads at an urban teaching hospital.,0,NA,0,NA,0,embryonic,1,embryonicembryonic,unreported,unreported,both,24,cordblood,wbcs,southernblot,0,0,NA,1,negative,HighMaternalStress.LowMaternalStress,Cordblood TRF kb,negative,0,meanssd,1,NA,NA,NA,NA,-1.732536463,6.98,8.74,NA,NA,0.89,1.05,6,18,NA,NA,NA,NA,NA,,-0.600107655,0.017801506
368,241,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Smoking (cigarettes/day),smoking,none,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Smoking (cigarettes/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.413,NA,NA,NA,NA,,0.413,0.012508287
369,242,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Protein (g/day),nutrition,protein,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,none,Protein (g/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.104,NA,NA,NA,NA,,0.104,0.017790636
370,243,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Lipids (g/day),nutrition,fats and oils,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,none,Lipids (g/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.238,NA,NA,NA,NA,,0.238,0.016180374
371,244,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Glucids (g/day),nutrition,other,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,none,Glucids (g/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.077,NA,NA,NA,NA,,0.077,0.017966857
372,245,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Alcohol (g/day),alcohol,more alcohol,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Alcohol (g/day),mTRF,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.006,NA,NA,NA,NA,,-0.006,0.018180509
373,246,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Calorie intake (kcal/day),nutrition,carbohydrates,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,none,Calorie intake (kcal/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.148,NA,NA,NA,NA,,0.148,0.017394032
374,247,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin A (?g/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Vitamin A (?g/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.321,NA,NA,NA,NA,,0.321,0.014627917
375,248,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin B1 (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,positive,Vitamin B1 (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.195,NA,NA,NA,NA,,0.195,0.01682538
376,249,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin B2 (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,positive,Vitamin B2 (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.132,NA,NA,NA,NA,,0.132,0.017553738
377,250,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin B3 (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,positive,Vitamin B3 (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.116,NA,NA,NA,NA,,0.116,0.017695801
378,251,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin B6 (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,positive,Vitamin B6 (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.127,NA,NA,NA,NA,,0.127,0.017600039
379,252,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin B9 (folic acid) (lg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Vitamin B9 (folic acid) (lg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.312,NA,NA,NA,NA,,0.312,0.014814325
380,253,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin C (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Vitamin C (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.32,NA,NA,NA,NA,,0.32,0.014648832
381,254,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin D (lg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,0,positive,Vitamin D (lg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.208,NA,NA,NA,NA,,0.208,0.016642614
382,255,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Vitamin E (mg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Vitamin E (mg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.326,NA,NA,NA,NA,,0.326,0.014522593
383,256,m,marcon2012,marcon,2012,Diet-related telomere shortening and chromosome stability,homo sapiens,Beta-carotene (lg/day),nutrition,vitamins,none,Mean age = 56,20440,4927.5,adult,44712.5,unreported,"Fifty-six subjects, enrolled in a previous study carried out in Tuscany.",0,NA,0,NA,20440,adult,1,adultadult,31,25,both,56,leukocytes,wbcs,southernblot,0,0,NA,1,positive,Beta-carotene (lg/day),mTRF,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.422,NA,NA,NA,NA,,0.422,0.012282653
384,366,m,martinsson2013,martinsson,2013,Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres,homo sapiens,Lithium treatment duration in bipolar patients,medicaltreatment,none,none,Median age = 50,18250,4927.5,adult,44712.5,NA,"Patients with clinical diagnosis of BD recruited from the Unit of Affective Disorders at Psychiatry Southwest, Huddinge Hospital, Stockholm.",0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,121,leukocytes,wbcs,qpcr,0,0,NA,0,none,Lithium treatment duration,Leukocyte ?Ct,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.29,NA,NA,NA,"The paper largely refers to leukocyte TL, but some of the figure captions say ""lymphocyte"". We have assumed that this is a typing error.",0.34,0.006518028
385,367,ss366,martinsson2013,martinsson,2013,Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres,homo sapiens,Lithium treatment duration for 30+ months in bipolar patients ,medicaltreatment,none,none,unreported,unreported,4927.5,unreported,44712.5,NA,"Patients with clinical diagnosis of BD recruited from the Unit of Affective Disorders at Psychiatry Southwest, Huddinge Hospital, Stockholm.",0,NA,0,NA,unreported,unreported,1,unreportedunreported,unreported,unreported,both,72,leukocytes,wbcs,qpcr,0,0,NA,1,none,Lithium treatment duration (in longer term patients),Leukocyte ?Ct,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.13,NA,NA,NA,"The paper largely refers to leukocyte TL, but some of the figure captions say ""lymphocyte"". We have assumed that this is a typing error.",0.18,0.013186616
386,368,m,martinsson2013,martinsson,2013,Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres,homo sapiens,Number of depressive episodes in bipolar patients,psychiatric,depression and anxiety,depression,Median age = 50,18250,4927.5,adult,44712.5,unreported,"Patients with clinical diagnosis of BD recruited from the Unit of Affective Disorders at Psychiatry Southwest, Huddinge Hospital, Stockholm.",0,NA,0,NA,18250,adult,1,adultadult,unreported,unreported,both,190,leukocytes,wbcs,qpcr,0,0,NA,1,none,Depressive episodes (bipolar patients),Leukocyte ?Ct,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.2,NA,NA,NA,"The paper largely refers to leukocyte TL, but some of the figure captions say ""lymphocyte"". We have assumed that this is a typing error.",-0.2,0.00487619
387,433,m,masi2011,masi,2011,"Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis",homo sapiens,Periodontitis (cases vs controls),disease,other,none,Mean age = 46.85,17100.25,4927.5,adult,44712.5,unreported,563 participants from subjects referred to the UCL Eastman Dental Institute in London between 2002 and 2006.,0,NA,0,NA,17100.25,adult,1,adultadult,305,258,both,563,leukocytes,wbcs,qpcr,0,0,NA,1,negative,PeriodontitisCases.Controls,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.310399917,1.12,1.23,NA,NA,0.31,0.42,356,207,NA,NA,NA,NA,NA,,-0.148017467,0.001702245
388,434,sg433,masi2011,masi,2011,"Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis",homo sapiens,Aggressive periodontitis (cases vs controls),disease,other,none,unreported,unreported,4927.5,unreported,44712.5,unreported,563 participants from subjects referred to the UCL Eastman Dental Institute in London between 2002 and 2006.,0,NA,0,NA,unreported,unreported,1,unreportedunreported,unreported,unreported,both,278,leukocytes,wbcs,qpcr,0,0,NA,0,negative,AggressivePeriodontitisCases.Controls,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.200451251,1.15,1.23,NA,NA,0.33,0.42,71,207,NA,NA,NA,NA,NA,,-0.087081396,0.003555564
389,435,sg433,masi2011,masi,2011,"Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis",homo sapiens,Chronic periodontitis (cases vs controls),disease,other,none,unreported,unreported,4927.5,unreported,44712.5,unreported,563 participants from subjects referred to the UCL Eastman Dental Institute in London between 2002 and 2006.,0,NA,0,NA,unreported,unreported,1,unreportedunreported,unreported,unreported,both,492,leukocytes,wbcs,qpcr,0,0,NA,1,negative,ChronicPeriodontitisCases.Controls,LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.305250956,1.12,1.23,NA,NA,0.31,0.42,285,207,NA,NA,NA,NA,NA,,-0.149012768,0.001947217
390,436,sg433,masi2011,masi,2011,"Oxidative stress, chronic inflammation, and telomere length in patients with periodontitis",homo sapiens,Severity of periodontitis (clinical attachment levels in mm),disease,other,none,Mean age = 46.85,17100.25,4927.5,adult,44712.5,unreported,563 participants from subjects referred to the UCL Eastman Dental Institute in London between 2002 and 2006.,0,NA,0,NA,17100.25,adult,1,adultadult,305,258,both,563,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Severity of periodontitis,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.2,NA,NA,NA,NA,,-0.2,0.001639858
391,127,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Revised Conflict Tactics Scale - Severe physical abuse,psychosocial,traumatic experience,more adversity,0-17 years,3102.5,"4,745",child,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16644,adult,0,childadult,1135,0,female,663,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeverePhysicalAbuse.None,Ln leukocyte RTL,negative,0,meanssd,1,NA,NA,NA,NA,0.042147873,-0.722,-0.736,NA,NA,0.4,0.3,193,470,NA,NA,NA,NA,NA,,0.019143006,0.001509467
392,128,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Revised Conflict Tactics Scale - Moderate physical abuse,psychosocial,traumatic experience,more adversity,0-17 years,3102.5,"4,745",child,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16625.75,adult,0,childadult,1135,0,female,753,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ModeratePhysicalAbuse.None,Ln leukocyte RTL,negative,0,meanssd,1,NA,NA,NA,NA,-0.123333333,-0.773,-0.736,NA,NA,0.3,0.3,283,470,NA,NA,NA,NA,NA,,-0.059628541,0.001320348
393,129,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Revised Conflict Tactics Scale - Mild physical abuse,psychosocial,traumatic experience,more adversity,0-17 years,3102.5,"4,745",child,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16589.25,adult,0,childadult,1135,0,female,654,leukocytes,wbcs,qpcr,0,0,NA,0,negative,MildPhysicalAbuse.None,Ln leukocyte RTL,negative,0,meanssd,1,NA,NA,NA,NA,-0.048319355,-0.752,-0.736,NA,NA,0.4,0.3,184,470,NA,NA,NA,NA,NA,,-0.021721947,0.001529949
394,130,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Sexual abuse - touch only,psychosocial,traumatic experience,more adversity,0-17 years,3102.5,"4,745",child,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16644,adult,0,childadult,1135,0,female,908,leukocytes,wbcs,qpcr,0,0,NA,0,negative,TouchOnlySexualAbuse.None,Ln leukocyte RTL,negative,0,meanssd,1,NA,NA,NA,NA,0.013333333,-0.74,-0.744,NA,NA,0.3,0.3,248,660,NA,NA,NA,NA,NA,,0.005940774,0.001102458
395,131,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Sexual abuse - forced sex,psychosocial,traumatic experience,more adversity,0-17 years,3102.5,"4,745",child,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16589.25,adult,0,childadult,1135,0,female,879,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ForcedSexAbuse.None,Ln leukocyte RTL,negative,0,meanssd,1,NA,NA,NA,NA,-0.016666667,-0.749,-0.744,NA,NA,0.3,0.3,219,660,NA,NA,NA,NA,NA,,-0.007208462,0.001138834
396,132,m,mason2015,mason,2015,Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood,homo sapiens,Smoker status,smoking,none,none,unreported,unreported,"4,745",unreported,44712.5,unreported,"1,135 participants in the Nurses’ Health Study II (NHSII)",0,NA,0,NA,16619.66667,adult,0,unreportedadult,1135,0,female,1135,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smoking status,Ln leukocyte RTL,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.058,NA,NA,NA,NA,,-0.058,0.000875911
397,467,m,menon2012,menon,2012,Short Fetal Leukocyte Telomere Length and Preterm Prelabor Rupture of the Membranes,homo sapiens,Premature birth (vs term birth),other,birth weight or term,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"A total of 132 fetuses from 28 prelabor rupture of membrane births, 69 preterm births with intact membranes, and 35 normal term births.",0,NA,0,NA,0,embryonic,1,embryonicembryonic,unreported,unreported,both,104,leukocytes,wbcs,qpcr,0,0,NA,1,none,PretermBirth.TermBirth,LTL bp,positive,0,meanssd,1,NA,NA,NA,NA,0.661631346,11546.4,9011.1,NA,NA,4348.2,2497.3,69,35,NA,NA,NA,NA,NA,,0.298394696,0.008056789
398,468,m,menon2012,menon,2012,Short Fetal Leukocyte Telomere Length and Preterm Prelabor Rupture of the Membranes,homo sapiens,Prelabor rupture of membranes (vs term birth),other,birth weight or term,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,"A total of 132 fetuses from 28 prelabor rupture of membrane births, 69 preterm births with intact membranes, and 35 normal term births.",0,NA,0,NA,0,embryonic,1,embryonicembryonic,unreported,unreported,both,63,leukocytes,wbcs,qpcr,0,0,NA,0,none,PretermBirthWithMembraneRupture.TermBirth,LTL bp,positive,0,meanssd,1,NA,NA,NA,NA,0.340669709,9962.3,9011.1,NA,NA,3124.1,2497.3,28,35,NA,NA,NA,NA,NA,,0.166905626,0.01524292
399,308,m,mizutani2013,mizutani,2013,Environmental perturbations influence telomere dynamics in long-lived birds in their natural habitat,larus crassirostris,Increased food abundance (el niño vs mean of control years),nutrition,other,,4-28 years,5840,unavailable,adult,unavailable,330,"Gulls on on Kabushima Island, Japan",0,NA,NA,5840,6935,adult,1,adultadult,7,18,both,32,blood,rbcs,southernblot,0,1,NA,0,negative,ElNiño.ControlYears,Change in telomere length (kb),positive,0,meanssd,1,NA,NA,NA,NA,-0.772919525,-0.183529412,0.38,NA,NA,0.719411765,0.74,17,15,NA,NA,NA,NA,NA,Ages at first and last TL measurement are based on median of age bracket + 1 year.,-0.359863893,0.024444088
400,309,m,mizutani2013,mizutani,2013,Environmental perturbations influence telomere dynamics in long-lived birds in their natural habitat,larus crassirostris,Decreased food abundance (Great Japan earthquake & tsunami vs mean of control years),nutrition,other,,4-28 years,5840,unavailable,adult,unavailable,81,"Gulls on on Kabushima Island, Japan",0,NA,NA,5840,7300,adult,1,adultadult,7,18,both,32,blood,rbcs,southernblot,0,1,NA,0,positive,Earthquake.ControlYears,Change in telomere length (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.607388167,-0.65,-0.183529412,NA,NA,0.82,0.719411765,15,17,NA,NA,NA,NA,NA,Ages at first and last TL measurement are based on median of age bracket + 1 year.,-0.290068793,0.027058055
401,310,m,monickaraj2012,monickaraj,2012,Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes,homo sapiens,Diabetes status,disease,diabetes,none,36-48 years,15512.5,4927.5,adult,44712.5,unreported,290 participants from the Chennai Urban Rural Epidemiology Study (CURES): 145 diabetics & 145 controls.,0,NA,0,NA,15512.5,adult,1,adultadult,unreported,unreported,both,290,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Type 2 diabetes melitus status (vs controls),Whole blood T/S ratio,negative,0,meansse,1,NA,NA,NA,NA,-1.586206897,0.97,1.2,0.011,0.013,0.13245754,0.15654073,145,145,NA,NA,NA,NA,NA,,-0.621394711,0.001303926
402,422,m,nakajima2010,nakajima,2010,Nuclear size measurement is a simple method for the assessment of hepatocellular aging in non-alcoholic fatty liver disease: Comparison with telomere-specific quantitative FISH and p21 immunohistochemistry,homo sapiens,Non-alcoholic fatty liver disease (NAFLD using QFISH),disease,other,none,unreported,unreported,4927.5,unreported,44712.5,unreported,"Sixty-four patients (38 male, 26 female) diagnosed with NAFLD in 2003–2006 were selected from the files of the Department of Surgical Pathology of Kyoto Prefectural University of Medicine.",0,NA,0,NA,unreported,unreported,1,unreportedunreported,unreported,unreported,both,75,liver,other,qfish,0,0,NA,unreported,negative,NAFLDPatients.Controls,Liver RTI (relative telomere intensity),negative,0,meanssd,0,NA,NA,NA,NA,-0.821937618,0.845,1.101,NA,NA,0.287,0.435,64,11,NA,NA,NA,NA,NA,,-0.279214893,0.011488595
403,546,m,nawrot2010,nawrot,2010,"Telomere length and its associations with oxidized-LDL, carotid artery distensibility and smoking",homo sapiens,Smoking,smoking,none,none,42.5 years (16.5),15512.5,4927.5,adult,44712.5,unreported,FLEMENGHO cohort (Flemish Study on Environment Genes and Health Outcomes),0,NA,0,NA,15512.5,adult,1,adultadult,163,142,both,305,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Smoker vs. non-smoker,Mean TL in kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.23880597,6.75,6.91,NA,NA,0.67,0.67,89,216,NA,NA,NA,NA,NA,,-0.107925252,0.003213289
404,490,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Family income medium vs. high,socioeconomic,income,lower,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,70,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Lower family income (medium vs. high),T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.615384615,NA,NA,NA,NA,NA,NA,45,25,NA,NA,-0.32,NA,0.52,,-0.282827,0.012266904
405,491,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Family income low vs. high,socioeconomic,income,lower,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,39,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Lower family income (low vs. high),T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.634615385,NA,NA,NA,NA,NA,NA,14,25,NA,NA,-0.33,NA,0.52,,-0.291228999,0.022041179
406,492,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Parent education some college vs. college graduate,socioeconomic,education,lower,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,58,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Less parental education (some college vs. college graduate),T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-0.115384615,NA,NA,NA,NA,NA,NA,9,49,NA,NA,-0.06,NA,0.52,,-0.041740778,0.01748278
407,493,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Parent education high school vs. college,socioeconomic,education,lower,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,58,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Lesser parental education (high school vs. college),T/S ratio,negative,1,dbeta,1,NA,NA,NA,NA,-1.038461538,NA,NA,NA,NA,NA,NA,9,49,NA,NA,-0.54,NA,0.52,,-0.351939577,0.013466995
408,494,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Daily fruit servings,nutrition,"fruit, legumes and vegetables",none,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,70,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Daily fruit servings,T/S ratio,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.063076923,0.02,1.64,0.52,,0.113076923,0.014124503
409,495,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,Daily vegetable servings,nutrition,"fruit, legumes and vegetables",none,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,70,wholeblood,wbcs,qpcr,0,0,NA,0,positive,Daily vegetable servings,T/S ratio,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0,1.7,0.52,,0.05,0.01442038
410,496,m,needham2012,needham,2012,Socioeconomic status and cell aging in children,homo sapiens,PAQ-C Physical activity score,physicalactivity,more activity,none,9.9 years (sd 1.59),3613.5,4927.5,child,44712.5,unreported,70 US children from the AMERICO (Admixture Mapping for Ethnic and Racial Insulin Complex Outcomes),0,NA,0,NA,3613.5,child,1,childchild,36,34,both ,70,wholeblood,wbcs,qpcr,0,0,NA,0,positive,PAQ-C Physical activity score,T/S ratio,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.027692308,0.02,0.72,0.52,,0.077692308,0.014318322
411,208,m,needham2015,needham,2015,"Depression, anxiety and telomere length in young adults: Evidence from the National Health and Nutrition Examination Survey",homo sapiens,Major depression or depressed affect (versus no depression),psychiatric,depression and anxiety,depression,Mean age = 29.4,10731,4927.5,adult,44712.5,unreported,"1290 participants from the National Health and Nutrition Examination Survey, 1999–2002",0,NA,0,NA,10731,adult,1,adultadult,657,507,both,1164,leukocytes,wbcs,qpcr,0,0,NA,0,negative,MajorDepressionOrDepressedAffect.NoDepression,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.053518084,1.12,1.14,NA,NA,0.2,0.4,198,966,NA,NA,NA,NA,NA,,-0.02010393,0.00085915
412,209,m,needham2015,needham,2015,"Depression, anxiety and telomere length in young adults: Evidence from the National Health and Nutrition Examination Survey",homo sapiens,Generalised anxiety or panic disorder (versus no anxiety),psychiatric,depression and anxiety,anxiety,Mean age = 29.4,10731,4927.5,adult,44712.5,unreported,"1290 participants from the National Health and Nutrition Examination Survey, 1999–2002",0,NA,0,NA,10731,adult,1,adultadult,657,507,both,1164,leukocytes,wbcs,qpcr,0,0,NA,0,negative,GeneralisedAnxietyOrPanicDisorder.NoAnxiety,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.053797276,1.12,1.14,NA,NA,0.2,0.4,212,952,NA,NA,NA,NA,NA,,-0.020758698,0.000859104
413,210,m,nettle2014,nettle,2014,An experimental demonstration that early-life competitive disadvantage accelerates telomere loss,sturnus vulgaris,Being small relative to brood competitors,socioeconomic,relative status,,3-12 days,7.5,365,juvenile,8358.5,9,"A total of 132 chicks were cross-fostered and weighed during the course of the study. Of these, 48 chicks from 12 broods were chosen as focal birds and were subjected to blood sampling and either the DIS or ADV treatment.",0,NA,NA,3,12,juvenile,1,juvenilejuvenile,unreported,unreported,both,38,wholeblood,rbcs,qpcr,1,1,induce,1,negative,LargeRelativeToBrood.SmallRelativeToBrood,Change in RBCTL T/S ratio between day 3 and day 12 ,negative,1,dbeta,1,NA,NA,NA,NA,-0.232,NA,NA,NA,NA,NA,NA,19,19,NA,NA,-0.232,NA,1,,-0.115227341,0.026314098
414,211,x36,nettle2014,nettle,2014,An experimental demonstration that early-life competitive disadvantage accelerates telomere loss,sturnus vulgaris,Being small relative to brood competitors,socioeconomic,relative status,,3-12 days,7.5,365,juvenile,8358.5,9,"A total of 132 chicks were cross-fostered and weighed during the course of the study. Of these, 48 chicks from 12 broods were chosen as focal birds and were subjected to blood sampling and either the DIS or ADV treatment.",0,NA,NA,NA,12,juvenile,1,juvenilejuvenile,unreported,unreported,both,38,wholeblood,rbcs,qpcr,1,0,induce,1,negative,LargeRelativeToBrood.SmallRelativeToBrood,RBCTL T/S ratio on day 12,negative,0,meanssd,1,NA,NA,NA,NA,-0.75842085,1.53,1.892,NA,NA,0.517,0.434,19,19,NA,NA,NA,NA,NA,,-0.354572556,0.020658447
415,696,m,ngom2011,ngom,2011,Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden,homo sapiens,Season of birth: being born in hungry/high infection vs. harvest/low infection,other,other,none,Birth,0,"5,110",embryonic,44712.5,unreported,Rural Gambians,0,NA,0,NA,7774.5,adult,0,embryonicadult,0,60,male,58,CD4+ T cells,wbcs,qpcr,0,0,NA,0,positive,Born in hungry/high infection vs. harvest/low infection season,Ct from qPCR of known number of cells,negative,0,meansse,1,NA,NA,NA,NA,0.229718353,0.03,0.02,0.010204082,0.005612245,0.053994927,0.030739532,28,30,NA,NA,NA,NA,NA,"Note that Ct is an inverse measure of telomere length, hence a higher mean represents shorter TL.",0.114041966,0.017090491
416,697,m,ngom2011,ngom,2011,Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden,homo sapiens,Season of birth: hungry/high infection vs. harvest/low infection,other,other,none,Birth,0,"5,110",embryonic,44712.5,unreported,Rural Gambians,0,NA,0,NA,7774.5,adult,0,embryonicadult,0,60,male,60,CD8+ T cells,wbcs,qpcr,0,0,NA,0,positive,Born in hungry/high infection vs. harvest/low infection season,Ct from qPCR of known number of cells,negative,0,meansse,1,NA,NA,NA,NA,0.382795944,0.04,0.01,0.01122449,0.016836735,0.061479064,0.092218596,30,30,NA,NA,NA,NA,NA,"Note that Ct is an inverse measure of telomere length, hence a higher mean represents shorter TL.",0.187985685,0.0157724
417,455,m,noureddine2011,noureddine,2011,Pulmonary Artery Smooth Muscle Cell Senescence Is a Pathogenic Mechanism for Pulmonary Hypertension in Chronic Lung Disease,homo sapiens,Smoking (pack years) in COPD patients,smoking,none,none,Mean age = 64.1,23396.5,4927.5,adult,44712.5,NA,124 patients with COPD investigated by right heart catheterization,0,NA,0,NA,23396.5,adult,1,adultadult,29,95,both,124,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking pack years,LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.05,NA,NA,NA,NA,,0.05,0.008089482
418,578,m,nzeitchueng2011,nzeitchueng,2011,Telomere length in vascular tissues from patients with atherosclerotic disease,homo sapiens,Atherosclerotic disease,disease,cardiovascular,none,67 years (sd 9 years),24455,4927.5,adult,44712.5,unreported,Patients with atherosclerotic disease and healthy controls,0,NA,0,NA,24455,adult,1,adultadult,15,39,both,54,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Atherosclerotic disease vs. control,Mean TRF in kb,negative,1,meansse,0,NA,NA,NA,NA,-0.29688876,6.18,6.41,0.13,0.18,0.78,0.763675324,36,18,NA,NA,NA,NA,NA,,-0.138603848,0.018149944
419,133,m,odonovan2011,odonovan,2011,Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder,homo sapiens,PTSD status,psychiatric,PTSD,none,Mean age = 30.55,11150.75,4927.5,adult,44712.5,unreported,"43 adults with chronic PTSD (n=18 with multiple categories of childhood trauma) and 47 control subjects (none with multiple categories of childhood trauma) (mean age 30.55, SD 7.44).",0,NA,0,NA,11150.75,adult,1,adultadult,45,43,both,88,leukocytes,wbcs,qpcr,0,0,NA,1,negative,PTSD.NoPTSD,LTL bp,negative,0,meansse,1,NA,NA,NA,NA,-0.387186732,6594.1,6798.61,81.5,77.88,528.1803669,528.2078591,42,46,NA,NA,NA,NA,NA,,-0.189875108,0.010680399
420,134,sg133,odonovan2011,odonovan,2011,Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder,homo sapiens,PTSD severity (PTSD sufferers only),psychiatric,PTSD,none,Mean age = 30.15,11004.75,4927.5,adult,44712.5,unreported,"43 adults with chronic PTSD (n=18 with multiple categories of childhood trauma) and 47 control subjects (none with multiple categories of childhood trauma) (mean age 30.55, SD 7.44).",0,NA,0,NA,11004.75,adult,1,adultadult,20,22,both,42,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PTSD severity,LTL bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.12,NA,NA,NA,NA,,-0.12,0.023692862
421,135,m,odonovan2011,odonovan,2011,Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder,homo sapiens,Cumulative childhood traumas - Life Stressor Checklist (all participants),psychosocial,traumatic experience,more adversity,0-14 years,2555,4927.5,child,44712.5,unreported,"43 adults with chronic PTSD (n=18 with multiple categories of childhood trauma) and 47 control subjects (none with multiple categories of childhood trauma) (mean age 30.55, SD 7.44).",0,NA,0,NA,11150.75,adult,0,childadult,45,43,both,88,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of childhood traumas (all participants),LTL bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.27,NA,NA,NA,NA,,-0.27,0.009879476
422,136,sg135,odonovan2011,odonovan,2011,Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder,homo sapiens,Cumulative childhood traumas - Life Stressor Checklist (PTSD sufferers only),psychosocial,traumatic experience,more adversity,0-14 years,2555,4927.5,child,44712.5,unreported,"43 adults with chronic PTSD (n=18 with multiple categories of childhood trauma) and 47 control subjects (none with multiple categories of childhood trauma) (mean age 30.55, SD 7.44).",0,NA,0,NA,11004.75,adult,0,childadult,20,22,both,42,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of childhood traumas (PTSD sufferers only),LTL bp,negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.42,NA,NA,NA,NA,,-0.42,0.016544316
423,137,sg133ss135,odonovan2011,odonovan,2011,Childhood trauma associated with short leukocyte telomere length in posttraumatic stress disorder,homo sapiens,One or none vs multiple childhood traumas - Life Stressor Checklist (PTSD sufferers),psychosocial,traumatic experience,more adversity,0-14 years,2555,4927.5,child,44712.5,unreported,"43 adults with chronic PTSD (n=18 with multiple categories of childhood trauma) and 47 control subjects (none with multiple categories of childhood trauma) (mean age 30.55, SD 7.44).",0,NA,0,NA,11004.75,adult,0,childadult,20,22,both,41,leukocytes,wbcs,qpcr,0,0,NA,1,negative,MultipleChildhoodTraumas.ZeroToOneChildhoodTrauma,LTL bp,negative,0,meanssd,1,NA,NA,NA,NA,-2.455937902,6480.45,6727.88,NA,NA,107.8,94.94,18,23,NA,NA,NA,NA,NA,,-0.773087026,0.004046865
424,498,m,o'donovan2012,o'donovan,2012,Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length,homo sapiens,Anticipatory threat appraisal,other,other,none,61.87 years (sd 6.51),22582.55,"4,745",adult,44712.5,1410,Healthy postemenopausal carer and control women,0,NA,0,NA,22582.55,adult,1,adultadult,63,0,female,63,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Anticipatory threat appraisal,T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.32,NA,NA,NA,,-0.32,0.012994932
425,499,m,o'donovan2012,o'donovan,2012,Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length,homo sapiens,Anticipatory challenge appraisal,other,other,none,61.87 years (sd 6.51),22582.55,"4,745",adult,44712.5,1410,Healthy postemenopausal carer and control women,0,NA,0,NA,22582.55,adult,1,adultadult,63,0,female,63,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Anticipatory challenge appraisal,T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.15,NA,NA,NA,,0.2,0.014864516
426,500,m,o'donovan2012,o'donovan,2012,Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length,homo sapiens,Retrospective threat appraisal,other,other,none,61.87 years (sd 6.51),22582.55,"4,745",adult,44712.5,1410,Healthy postemenopausal carer and control women,0,NA,0,NA,22582.55,adult,1,adultadult,63,0,female,63,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Retrospective threat appraisal,T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.17,NA,NA,NA,,-0.17,0.015210245
427,501,m,o'donovan2012,o'donovan,2012,Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length,homo sapiens,Retrospective challenge appraisal,other,other,none,61.87 years (sd 6.51),22582.55,"4,745",adult,44712.5,1410,Healthy postemenopausal carer and control women,0,NA,0,NA,22582.55,adult,1,adultadult,63,0,female,63,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Retrospective challenge appraisal,T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.05,NA,NA,NA,,0.1,0.015808065
428,502,m,o'donovan2012,o'donovan,2012,Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length,homo sapiens,Caregiver status,psychosocial,caregiving,more adversity,61.87 years (sd 6.51),22582.55,"4,745",adult,44712.5,1410,Healthy postemenopausal carer and control women,0,NA,0,NA,22582.55,adult,1,adultadult,63,0,female,63,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Caregiver status,T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.14,NA,NA,NA,,0.19,0.014985536
429,615,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Major life losses, 1 vs. none",psychosocial,traumatic experience,more adversity,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,567,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Major life losses, 1 vs. none",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.119738073,NA,NA,NA,NA,NA,NA,280,287,NA,NA,-128,NA,1069,,-0.059757491,0.001754189
430,616,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Major life losses, 2 or more vs. none",psychosocial,traumatic experience,more adversity,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,367,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Major life losses, 2 or more vs. none",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.066417212,NA,NA,NA,NA,NA,NA,80,287,NA,NA,71,NA,1069,,0.027411784,0.002728136
431,617,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Education, BA degree vs. higher degree",socioeconomic,education,lower,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,282,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Education, BA degree vs. higher degree",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.04303087,NA,NA,NA,NA,NA,NA,163,119,NA,NA,-46,NA,1069,,-0.021247129,0.003555506
432,613,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Perceived stress scale, score of 3 or more versus 0-2",psychosocial,stress,more adversity,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,647,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Perceived stress scale, score of 3 or more versus 0-2",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.120673527,NA,NA,NA,NA,NA,NA,364,283,NA,NA,-129,NA,1069,,-0.059755087,0.001536953
433,614,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Recent major stressors, 1 or more vs. none",psychosocial,stress,more adversity,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,647,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Recent major stressors, 1 or more vs. none",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.169317119,NA,NA,NA,NA,NA,NA,131,516,NA,NA,181,NA,1069,,0.067881928,0.001533754
434,618,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Education, AA/tech vs. higher degree",socioeconomic,education,lower,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,216,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Education, AA/tech vs. higher degree",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.113189897,NA,NA,NA,NA,NA,NA,97,119,NA,NA,-121,NA,1069,,-0.056211613,0.004621816
435,619,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Education, some college vs. higher degree",socioeconomic,education,lower,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,285,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Education, some college vs. higher degree",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.083255379,NA,NA,NA,NA,NA,NA,166,119,NA,NA,-89,NA,1069,,-0.04102317,0.003509285
436,620,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Education, high school or less vs. higher degree",socioeconomic,education,lower,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,221,leukocytes,wbcs,qpcr,0,0,NA,1,negative,"Education, high school or less vs. higher degree",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.28344247,NA,NA,NA,NA,NA,NA,102,119,NA,NA,-303,NA,1069,,-0.139911482,0.00436924
437,621,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Current marital partner, no vs. yes",psychosocial,social network,more adversity,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,648,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Current marital partner, no vs. yes",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.018709074,NA,NA,NA,NA,NA,NA,164,484,NA,NA,20,NA,1069,,0.008134063,0.001545391
438,622,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Smoking, former vs. never",smoking,none,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,492,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Smoking, former vs. never",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.049579046,NA,NA,NA,NA,NA,NA,187,305,NA,NA,53,NA,1069,,0.024059027,0.002034303
439,623,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Smoking, current vs. never",smoking,none,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,460,leukocytes,wbcs,qpcr,0,0,NA,1,negative,"Smoking, current vs. never",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.274087933,NA,NA,NA,NA,NA,NA,155,305,NA,NA,-293,NA,1069,,-0.1284794,0.002107317
440,626,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Current health, good or very good vs. excellent",other,other,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,596,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Current health, good or very good vs. excellent",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.065481759,NA,NA,NA,NA,NA,NA,395,201,NA,NA,70,NA,1069,,0.030943016,0.001677455
441,627,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Current health, fair vs. excellent",other,other,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,239,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Current health, fair vs. excellent",T/S ratio converted to bp,positive,1,dbeta,1,NA,NA,NA,NA,0.106641721,NA,NA,NA,NA,NA,NA,38,201,NA,NA,114,NA,1069,,0.038966295,0.004188931
442,628,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Current health, poor vs. excellent",other,other,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,214,leukocytes,wbcs,qpcr,0,0,NA,1,negative,"Current health, poor vs. excellent",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.503274088,NA,NA,NA,NA,NA,NA,13,201,NA,NA,-538,NA,1069,,-0.11935615,0.004562024
443,624,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Cardiovascular disease or diabetes, yes vs. no",disease,other,none,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,647,leukocytes,wbcs,qpcr,0,0,NA,1,negative,"Cardiovascular disease or diabetes, yes vs. no",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.319925164,NA,NA,NA,NA,NA,NA,123,524,NA,NA,-342,NA,1069,,-0.124556676,0.001500328
444,625,m,parks2009,parks,2009,"Telomere length, current perceived stress, and urinary stress hormones in women",homo sapiens,"Depression, ever diagnosed vs. never",psychiatric,depression and anxiety,depression,"35-74 years, mean approx 54",19710,"4,745",adult,44712.5,unreported,Members of National Institute of Environmental Health Sciences Sister Study (sisters of women with breast cancer),0,NA,0,NA,19710,adult,1,adultadult,647,0,female,647,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Depression, ever diagnosed vs. never",T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.072965388,NA,NA,NA,NA,NA,NA,139,508,NA,NA,-78,NA,1069,,-0.029954147,0.001545211
445,550,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Chronic vs. early schizophrenia,psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Chronic vs. early schizophrenia,Log transformed T/S ratio,negative,1,meansse,1,NA,NA,NA,NA,-1.622698102,0.911,1.204,0.028,0.027,0.185730988,0.174979999,44,42,NA,NA,NA,NA,NA,,-0.629951335,0.004280042
446,551,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Total PANSS score (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Total PANSS score,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.238,NA,NA,NA,NA,,-0.238,0.010469653
447,552,ss551,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Negative PANSS score (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Negative PANSS score,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.318,NA,NA,NA,NA,,-0.318,0.009505624
448,553,ss551,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Positive PANSS score (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Positive PANSS score,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.143,NA,NA,NA,NA,,-0.143,0.011288472
449,554,ss551,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,General PANNS score (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,0,negative,General PANNS score,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.097,NA,NA,NA,NA,,-0.097,0.011544359
450,555,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Patient functioning (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Patient functioning,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.036,NA,NA,NA,NA,,-0.036,0.011734232
451,556,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Severity of depressive symptoms,psychiatric,depression and anxiety,depression,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Severity of depressive symptoms,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.029,NA,NA,NA,NA,,-0.029,0.011744926
452,557,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Number of hospital admissions (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of hospital admissions,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.466,NA,NA,NA,NA,,-0.466,0.007209938
453,558,m,pawelczyk2015,pawelcyk,2015,"Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia",homo sapiens,Number of psychotic episodes (schizophrenia),psychiatric,schizophrenia,none,37.71 years,13764.15,4927.5,adult,44712.5,NA,"Schizophrenia patients from Lodz, Poland",0,NA,0,NA,13764.15,adult,1,adultadult,35,51,both,86,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of psychotic episodes,Log transformed T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.594,NA,NA,NA,NA,,-0.594,0.004927309
454,630,m,pawlas2015,pawlas,2015,"Telomere length, telomerase expression, and oxidative stress in lead smelters",homo sapiens,Being a lead smelter vs. control,environmentalhazard,none,none,39 years (sd 10),14235,"5,110",adult,44712.5,4635.5,Lead smelters and matched controls from Poland,0,NA,0,NA,14235,adult,1,adultadult,0,404,male,391,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Lead smelter vs. control,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.565186821,0.928,1.126,NA,NA,0.329,0.4514,331,60,NA,NA,NA,NA,NA,,-0.199607115,0.00236385
455,320,m,pedroso2015,pedroso,2015,Inflammatory biomarkers and telomere length in women with polycystic ovary syndrome,homo sapiens,Polycystic ovary syndrome status,disease,other,none,Mean = 25.79 years,9413.35,"4,745",adult,44712.5,unreported,"274 volunteers; 150 women with PCOS & 124  healthy controls from the Gynecology Endocrinology, Infertility & Contraception Outpatient Services of the Human Reproduction Division, Ribeirao Preto Medical School, University of Sao Paulo, Brazil.",0,NA,0,NA,9413.35,adult,1,adultadult,274,0,female,274,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PCOSPatients.Controls,Leukocyte telomere length (T/S ratio),positive,0,meanssd,1,NA,NA,NA,NA,0.142252297,1.2,1.11,NA,NA,0.7,0.54,150,124,NA,NA,NA,NA,NA,,0.070628385,0.00362655
456,268,m,phillips2013,phillips,2013,Do Symptoms of Depression Predict Telomere Length? Evidence From the West of Scotland Twenty-07 Study,homo sapiens,Number of long-standing physical illnesses (presence/absence coded using Royal College of General Practitioners morbidity codes),disease,other,none,Mean age  = 55.7,20330.5,4927.5,adult,44712.5,unreported,Participants from the West of Scotland Twenty-07 Study,0,NA,0,NA,20330.5,adult,1,adultadult,581,482,both,1063,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of long-standing illnesses,LTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,NA,,-0.13,0.000910062
457,654,m,plot2012,plot,2012,"Telomeres, age and reproduction in a long-lived reptile",dermochelys coriacea,Reproductive interval,other,other,,unreported,unreported,unavailable,adult,10950,NA,Leatherback turtles from French Guiana,0,NA,NA,NA,Unreported adults,adult,1,adultadult,30,0,female,30,erythrocytes,rbcs,qpcr,0,0,NA,1,negative,Having a short reproductive cycle (2 years) versus a long one (3 years),T/S ratio (described as T/C ratio),negative,0,meanssd,1,NA,NA,NA,NA,-5.190166251,1.33,3.85,NA,NA,0.26,0.81,21,9,NA,NA,NA,NA,NA,,-0.921835618,0.00077813
458,474,m,prather2011,prather,2011,Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality,homo sapiens,"Sleep quality (1 = very bad, 5 = very good)",sleep,more sleep,none,Mean age = 57.5,20987.5,"4,745",adult,44712.5,unreported,"263 healthy women between the ages of 50 and 65 were recruited through flyers and posters in the San Francisco Bay Area. Participants are part of an ongoing prospective study on telomere length change over the course of a year, examining the effects of knowing one’s telomere length on behavior and psychological stress.",1,puterman2015,1,NA,20987.5,adult,1,adultadult,245,0,female,245,leukocytes,wbcs,qpcr,0,0,NA,1,positive,Sleep quality,LTL bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.14,NA,NA,NA,NA,,0.14,0.003939279
459,475,m,prather2011,prather,2011,Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality,homo sapiens,Time in bed (hours),sleep,more sleep,none,Mean age = 57.5,20987.5,"4,745",adult,44712.5,unreported,"263 healthy women between the ages of 50 and 65 were recruited through flyers and posters in the San Francisco Bay Area. Participants are part of an ongoing prospective study on telomere length change over the course of a year, examining the effects of knowing one’s telomere length on behavior and psychological stress.",1,puterman2015,1,NA,20987.5,adult,1,adultadult,245,0,female,245,leukocytes,wbcs,qpcr,0,0,NA,0,none,Time in bed,LTL bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.06,NA,NA,NA,NA,,-0.06,0.004068906
460,476,m,prather2011,prather,2011,Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality,homo sapiens,Sleep duration (hours) ,sleep,more sleep,none,Mean age = 57.5,20987.5,"4,745",adult,44712.5,unreported,"263 healthy women between the ages of 50 and 65 were recruited through flyers and posters in the San Francisco Bay Area. Participants are part of an ongoing prospective study on telomere length change over the course of a year, examining the effects of knowing one’s telomere length on behavior and psychological stress.",1,puterman2015,1,NA,20987.5,adult,1,adultadult,245,0,female,245,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Sleep duration,LTL bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.01,NA,NA,NA,NA,,0.01,0.004097541
461,477,m,prather2011,prather,2011,Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality,homo sapiens,Sleep onset latency (minutes),sleep,less sleep,none,Mean age = 57.5,20987.5,"4,745",adult,44712.5,unreported,"263 healthy women between the ages of 50 and 65 were recruited through flyers and posters in the San Francisco Bay Area. Participants are part of an ongoing prospective study on telomere length change over the course of a year, examining the effects of knowing one’s telomere length on behavior and psychological stress.",1,puterman2015,1,NA,20987.5,adult,1,adultadult,245,0,female,245,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Sleep onset latency,LTL bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.11,NA,NA,NA,NA,,-0.11,0.00399978
462,479,m,prather2011,prather,2011,Shorter Leukocyte Telomere Length in Midlife Women with Poor Sleep Quality,homo sapiens,Income,socioeconomic,income,higher,Mean age = 57.5,20987.5,"4,745",adult,44712.5,unreported,"263 healthy women between the ages of 50 and 65 were recruited through flyers and posters in the San Francisco Bay Area. Participants are part of an ongoing prospective study on telomere length change over the course of a year, examining the effects of knowing one’s telomere length on behavior and psychological stress.",1,puterman2015,1,NA,20987.5,adult,1,adultadult,245,0,female,245,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Income,LTL bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.004,NA,NA,NA,,0.054,0.004074494
463,698,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep quality,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,granulocytes,wbcs,qpcr,0,0,NA,0,negative,PQSI global sleep quality score (higher is worse),Granulocyte T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.19,NA,NA,NA,NA,,-0.19,0.010803526
464,699,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep duration,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,granulocytes,wbcs,qpcr,0,0,NA,1,positive,Diary sleep duration report,Granulocyte T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.316,NA,NA,NA,NA,,0.316,0.009421619
465,700,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep quality,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,pbmcs,wbcs,qpcr,0,0,NA,0,negative,PQSI global sleep quality score (higher is worse),PBMC T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.16,NA,NA,NA,NA,,-0.16,0.011040179
466,701,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep duration,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,pbmcs,wbcs,qpcr,0,0,NA,1,positive,Diary sleep duration report,PBMC T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.25,NA,NA,NA,NA,,0.25,0.01021984
467,702,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep quality,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,CD8+ T cells,wbcs,qpcr,0,0,NA,1,negative,PQSI global sleep quality score (higher is worse),CD8+ T cell T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.27,NA,NA,NA,NA,,-0.27,0.009994354
468,703,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep duration,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,CD8+ T cells,wbcs,qpcr,0,0,NA,1,positive,Diary sleep duration report,CD8+ T cell T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.19,NA,NA,NA,NA,,0.19,0.010803526
469,704,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep quality,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,CD4+ T cells,wbcs,qpcr,0,0,NA,0,negative,PQSI global sleep quality score (higher is worse),CD4+ T cell T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.197,NA,NA,NA,NA,,-0.197,0.010742885
470,705,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep duration,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,CD4+ T cells,wbcs,qpcr,0,0,NA,1,positive,Diary sleep duration report,CD4+ T cell T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.26,NA,NA,NA,NA,,0.26,0.010108951
471,706,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep quality,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,B cells CD19+,wbcs,qpcr,0,0,NA,0,negative,PQSI global sleep quality score (higher is worse),B cell T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.15,NA,NA,NA,NA,,-0.15,0.011110538
472,707,m,prather2015,prather,2015,"Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women",homo sapiens,Sleep duration,sleep,more sleep,none,48 ± 12.5 years ,17520,4927.5,adult,44712.5,unreported,Obese volunteers from San Fransisco Bay Area,0,NA,0,NA,17520,adult,1,adultadult,71,16,both,87,B cells CD19+,wbcs,qpcr,0,0,NA,0,positive,Diary sleep duration report,B cell T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.1,NA,NA,NA,NA,,0.1,0.011396512
473,691,m,puterman2010,puterman,2010,The power of exercise: Buffering the effect of chronic stress on telomere length,homo sapiens,Perceived stress,psychosocial,stress,more adversity,61.87 ± 6.51 years ,22582.55,"4,745",adult,44712.5,unreported,Women from the San Francisco Bay Area,0,NA,0,NA,22582.55,adult,1,adultadult,59,0,female,59,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Perceived stress scale score, continuous",Leucocyte T/S ratio converted to bp,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.29,NA,NA,NA,NA,,-0.29,0.014463324
474,692,m,puterman2010,puterman,2010,The power of exercise: Buffering the effect of chronic stress on telomere length,homo sapiens,Vigourous physical exercise,physicalactivity,more activity,none,61.87 ± 6.51 years ,22582.55,"4,745",adult,44712.5,unreported,Women from the San Francisco Bay Area,0,NA,0,NA,22582.55,adult,1,adultadult,60,0,female,60,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Minutes of vigorous physical activity over 3 days,Leucocyte T/S ratio converted to bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.04,NA,NA,NA,NA,,0.04,0.016894959
475,210,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,Household income,socioeconomic,income,higher,50-65 years,20987.5,"4,745",adult,44712.5,unreported,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,0,negative,Household income ($ per year),LTL attrition bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.04,NA,NA,NA,,0.09,0.003755212
476,211,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,Education,socioeconomic,education,higher,50-65 years,20987.5,"4,745",adult,44712.5,unreported,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,0,negative,BachelorsDegreePlus.LowerThanDegree,LTL attrition bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.07,NA,NA,NA,,0.12,0.003707662
477,212,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,"Cumulative physical activity (Stanford Brief Activity Scale, SBAS)",physicalactivity,more activity,none,50-65 years,20987.5,"4,745",adult,44712.5,365,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,0,negative,"Cumulative physical activity (Stanford Brief Activity Scale, SBAS)",LTL attrition bp,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.04,NA,NA,NA,,-0.04,0.00380459
478,213,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,Cumulative typical diet (MESA Food Frequency Questionnaire - higher scores indicate healthier eating),nutrition,other,none,50-65 years,20987.5,"4,745",adult,44712.5,365,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,0,negative,Cumulative typical diet (MESA Food Frequency Questionnaire),LTL attrition bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.12,NA,NA,NA,,0.17,0.003599371
479,214,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,"Cumulative sleep quality (Pittsburgh Sleep Quality Index, PSQI) [higher is worse]",sleep,less sleep,none,50-65 years,20987.5,"4,745",adult,44712.5,365,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,0,negative,"Cumulative sleep quality (Pittsburgh Sleep Quality Index, PSQI)",LTL attrition bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.02,NA,NA,NA,,0.07,0.003779481
480,215,m,puterman2015,puterman,2015,Determinants of telomere attrition over 1 year in healthy older women: Stress and health behaviors matter,homo sapiens,"Major life events (e.g. loss of household, major financial difficulty, bereavement)",psychosocial,traumatic experience,more adversity,50-65 years,20987.5,"4,745",adult,44712.5,365,263 healthy midlife women (ranging 50 to 65 years) from the San Francisco Bay Area,0,NA,0,20987.5,21352.5,adult,1,adultadult,263,0,female,263,leukocytes,wbcs,qpcr,0,1,NA,1,positive,"Major life events (e.g. loss of household, major financial difficulty, bereavement)",LTL attrition bp,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.18,NA,NA,NA,,-0.18,0.003573472
481,521,m,ramirez2005,ramirez,2005,Stress-induced premature senescence in mononuclear cells from patients on long-term hemodialysis,homo sapiens,Regular hemodialysis,medicaltreatment,none,none,Average 54.5 years,19892.5,4927.5,adult,44712.5,2166,15 hemodialysis patients and matched controls,0,NA,0,NA,19892.5,adult,1,adultadult,13,17,both ,30,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Hemodialysis patient vs. control,MESF,negative,0,meansse,1,NA,NA,NA,NA,-1.494605685,8.2,11.5,0.4,0.7,1.549193338,2.711088342,15,15,NA,NA,NA,NA,NA,,-0.598616371,0.014197433
482,269,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Cardiovascular disease status,disease,cardiovascular,none,Mean age = 60 ,21900,4927.5,adult,44712.5,unreported,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,21900,adult,1,adultadult,1969,2986,both,4955,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Cardiovascular disease status,RTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.149,NA,NA,NA,NA,,-0.149,0.000192994
483,270,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Diabetes status,disease,diabetes,none,Mean age = 60 ,21900,4927.5,adult,44712.5,unreported,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,21900,adult,1,adultadult,1969,2986,both,4955,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Diabetes status,RTL T/S ratio,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.111,NA,NA,NA,NA,,-0.111,0.000196914
484,271,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Education,socioeconomic,education,higher,Mean age = 60 ,21900,4927.5,adult,44712.5,unreported,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,21900,adult,1,adultadult,1969,2986,both,4955,wholeblood,wbcs,qpcr,0,0,NA,1,positive,Education,RTL T/S ratio,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.123,NA,NA,NA,NA,,0.123,0.000195795
485,272,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Smoker status,smoking,none,none,Mean age = 60 ,21900,4927.5,adult,44712.5,unreported,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,21900,adult,1,adultadult,1969,2986,both,4955,wholeblood,wbcs,qpcr,0,0,NA,1,negative,Smoker status,RTL T/S ratio,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.05,NA,NA,NA,NA,,0.05,0.000200849
486,273,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Chronic kidney disease duration < 6 months vs ? 6 months -<5 years,disease,other,none,Mean age = 60.5,22082.5,4927.5,adult,44712.5,NA,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,22082.5,adult,1,adultadult,938,1523,both,2461,wholeblood,wbcs,qpcr,0,0,NA,1,negative,KidneyDiseaseUnder6Months.KidneyDisease6months-5years,RTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.1157091,0.935,0.957,NA,NA,0.188,0.203,2122,339,NA,NA,NA,NA,NA,Comparison groups may be meaningless as there was a u-shaped association between CKD & RTL.,-0.039845878,0.000405214
487,274,m,raschenberger2015,raschenberger,2015,Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population,homo sapiens,Chronic kidney disease duration < 6 months vs ? 5 years,disease,other,none,Mean age = 60.5,22082.5,4927.5,adult,44712.5,NA,4955 patients from the German Chronic Kidney Disease study (GCKD study),0,NA,0,NA,22082.5,adult,1,adultadult,1085,1595,both,2680,wholeblood,wbcs,qpcr,0,0,NA,0,negative,KidneyDiseaseUnder6Months.KidneyDiseaseOver5years,RTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.005216773,0.956,0.957,NA,NA,0.19,0.203,2341,339,NA,NA,NA,NA,NA,Comparison groups may be meaningless as there was a u-shaped association between CKD & RTL.,-0.001734072,0.000373271
488,459,m,raymond2013,raymond,2013,Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans,homo sapiens,Idiopathic dilated cardiomyopathy (IDC) patients (vs controls),disease,cardiovascular,none,Mean age = 45.5,16607.5,4927.5,adult,44712.5,unreported,"A total of 223 patients of black African ancestry with IDC and 227 controls randomly recruited from the same community who had no history of cardiovascular disease, were normotensive, and had no diabetes mellitus.",0,NA,0,NA,16607.5,adult,1,adultadult,195,255,both,450,leukocytes,wbcs,qpcr,0,0,NA,0,negative,IdiopathicDilatedCardiomyopathy.Controls,Log LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.150289017,0.058,0.084,NA,NA,0.173,0.173,223,227,NA,NA,NA,NA,NA,,-0.0749303,0.002202233
489,460,m,raymond2013,raymond,2013,Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans,homo sapiens,Regular alcohol intake (controls only),alcohol,more alcohol,none,Mean age = 39.9,1456.35,4927.5,child,44712.5,unreported,"A total of 223 patients of black African ancestry with IDC and 227 controls randomly recruited from the same community who had no history of cardiovascular disease, were normotensive, and had no diabetes mellitus.",0,NA,0,NA,1456.35,child,1,childchild,112,115,both,227,leukocytes,wbcs,qpcr,0,0,NA,0,negative,RegularDrinkers(Yes).RegularDrinkers(No),Log LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.037354049,0.079,0.086,NA,NA,0.211,0.173,81,146,NA,NA,NA,NA,NA,,-0.017892097,0.004421946
490,461,m,raymond2013,raymond,2013,Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans,homo sapiens,Regular alcohol intake (IDC patients only),alcohol,more alcohol,none,Mean age = 51.1,18651.5,4927.5,adult,44712.5,unreported,"A total of 223 patients of black African ancestry with IDC and 227 controls randomly recruited from the same community who had no history of cardiovascular disease, were normotensive, and had no diabetes mellitus.",0,NA,0,NA,18651.5,adult,1,adultadult,83,140,both,223,leukocytes,wbcs,qpcr,0,0,NA,1,negative,RegularDrinkers(Yes)+IDC.RegularDrinkers(No)+IDC,Log LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.391707131,0.005,0.068,NA,NA,0.139,0.164,31,192,NA,NA,NA,NA,NA,,-0.134287775,0.004343508
491,462,m,raymond2013,raymond,2013,Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans,homo sapiens,Regular smoking (controls only),smoking,none,none,Mean age = 39.9,1456.35,4927.5,child,44712.5,unreported,"A total of 223 patients of black African ancestry with IDC and 227 controls randomly recruited from the same community who had no history of cardiovascular disease, were normotensive, and had no diabetes mellitus.",0,NA,0,NA,1456.35,child,1,childchild,112,115,both,227,leukocytes,wbcs,qpcr,0,0,NA,0,negative,RegularSmokers(Yes).RegularSmokers(No),Log LTL (T/S ratio),positive,0,meanssd,1,NA,NA,NA,NA,0.010773404,0.085,0.083,NA,NA,0.187,0.185,73,154,NA,NA,NA,NA,NA,,0.005032032,0.004424555
492,463,m,raymond2013,raymond,2013,Relationship between average leucocyte telomere length and the presence or severity of idiopathic dilated cardiomyopathy in black Africans,homo sapiens,Regular smoking (IDC patients only),smoking,none,none,Mean age = 51.1,18651.5,4927.5,adult,44712.5,unreported,"A total of 223 patients of black African ancestry with IDC and 227 controls randomly recruited from the same community who had no history of cardiovascular disease, were normotensive, and had no diabetes mellitus.",0,NA,0,NA,18651.5,adult,1,adultadult,83,140,both,223,leukocytes,wbcs,qpcr,0,0,NA,1,negative,RegularSmokers(Yes)+IDC.RegularSmokers(No)+IDC,Log LTL (T/S ratio),negative,0,meanssd,1,NA,NA,NA,NA,-0.529232018,-0.014,0.066,NA,NA,0.066,0.163,38,185,NA,NA,NA,NA,NA,"It isn't clear what the negative T/S ratio means, but the paper says, ""Log T/S was negatively correlated with... regular smoking (P=0.021) in patients with IDC.""",-0.195158229,0.004167915
493,482,m,ren2010,ren,2010,Shorter Telomere Length in Peripheral Blood Cells Associated With Migraine in Womenhead_1693,homo sapiens,Migraine sufferers (vs controls),disease,other,none,Mean age at onset = 19.2,7008,"4,745",adult,44712.5,7473,"142 women with migraine and 143 unrelated control women matched for ethnicity, recruited from the local general population using advertising at Doctors Surgeries in Pharmacies, through media release in local radio, television & press .",0,NA,0,NA,17264.5,adult,1,adultadult,285,0,female,285,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Migraines.NoMigraines,PBMC T/S ratio,negative,1,beta,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.114,NA,NA,NA,,-0.114,0.0034302
494,483,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Childhood trauma index,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,0,childadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood Trauma Index,LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.022297521,-12.07,1.14,617.1,,-0.022297521,0.000340377
495,484,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Childhood trauma index,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,0,childadult,1228,632,both,1860,leukocytes,wbcs,qpcr,0,1,NA,1,positive,Childhood Trauma Index,Change in LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.050424299,-23.81,1.14,538.3,,-0.050424299,0.000535192
496,485,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Total physical activity (MET-h/week),physicalactivity,more activity,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Total physical activity (MET-h/week),LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.015785124,-0.17,57.3,617.1,,-0.015785124,0.000340546
497,486,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Total sedentary behaviour (h/week),physicalactivity,less activity,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Total sedentary behaviour (h/week),LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.012414195,-0.42,18.24,617.1,,-0.012414195,0.00034061
498,487,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Total physical activity (MET-h/week),physicalactivity,more activity,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,632,both,1860,leukocytes,wbcs,qpcr,0,1,NA,0,negative,Total physical activity (MET-h/week),Change in LTL base pairs,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.014902471,0.14,57.3,538.3,,0.064902471,0.000533401
499,488,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Total sedentary behaviour (h/week),physicalactivity,less activity,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,632,both,1860,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Total sedentary behaviour (h/week),Change in LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.016942226,-0.5,18.24,538.3,,-0.016942226,0.000537615
500,489,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cigarettes per day,smoking,none,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Cigarettes per day,LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.074242424,-5.39,8.5,617.1,,-0.074242424,0.00033697
501,490,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cigarettes per day,smoking,none,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,632,both,1860,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Cigarettes per day,Change in LTL base pairs,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.015790451,-1,8.5,538.3,,-0.015790451,0.000537655
502,491,x463,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Beeing teetotal (vs moderate drinkers),alcohol,less alcohol,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,613,both,2563,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ModerateDrinkers.Non-drinkers,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.02657592,NA,NA,NA,NA,NA,NA,2063,500,NA,NA,-16.4,NA,617.1,,-0.01053053,0.000390234
503,492,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Financial difficulties,socioeconomic,income,lower,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Self-reported financial difficulties,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.035261708,NA,NA,NA,NA,NA,NA,300,2636,NA,NA,-21.76,NA,617.1,,-0.010679621,0.000340638
504,493,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Beeing teetotal (vs moderate drinkers),alcohol,less alcohol,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1335,both,2563,leukocytes,wbcs,qpcr,0,1,NA,0,positive,ModerateDrinkers.Non-drinkers,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.004309864,NA,NA,NA,NA,NA,NA,2063,500,NA,NA,2.32,NA,538.3,,0.001707847,0.000390318
505,494,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Life events past year (1 vs none),psychosocial,traumatic experience,more adversity,Mean = 47.1 years,17191.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,341,both,2291,leukocytes,wbcs,qpcr,0,0,NA,0,negative,OneAdverseLifeEvent.NoAdverseLifeEvents,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.006773619,NA,NA,NA,NA,NA,NA,814,1477,NA,NA,-4.18,NA,617.1,,-0.003241872,0.000436672
506,495,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Life events past year (2 or more vs none),psychosocial,traumatic experience,more adversity,Mean = 47.1 years,17191.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,168,both,2118,leukocytes,wbcs,qpcr,0,0,NA,1,negative,TwoAdverseLifeEvents.NoAdverseLifeEvents,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.141614001,NA,NA,NA,NA,NA,NA,641,1477,NA,NA,-87.39,NA,617.1,,-0.064920575,0.000468393
507,496,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Life events past year (1 vs none),psychosocial,traumatic experience,more adversity,Mean = 47.1 years,17191.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1063,both,2291,leukocytes,wbcs,qpcr,0,1,NA,0,positive,OneAdverseLifeEvent.NoAdverseLifeEvents,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.021567899,NA,NA,NA,NA,NA,NA,814,1477,NA,NA,11.61,NA,538.3,,0.010321957,0.000436588
508,497,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Life events past year (2 or more vs none),psychosocial,traumatic experience,more adversity,Mean = 47.1 years,17191.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,890,both,2118,leukocytes,wbcs,qpcr,0,1,NA,0,positive,TwoAdverseLifeEvents.NoAdverseLifeEvents,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.022886866,NA,NA,NA,NA,NA,NA,641,1477,NA,NA,-12.32,NA,538.3,,-0.010513701,0.000472262
509,498,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Being married or having a partner,psychosocial,social network,more adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,3022,both,4972,leukocytes,wbcs,qpcr,0,0,NA,0,positive,MaritalStatus,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.013660671,NA,NA,NA,NA,NA,NA,2936,2036,NA,NA,8.43,NA,617.1,,0.006717351,0.000201149
510,499,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cardiovascular disease,disease,cardiovascular,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cardiovascular disease status,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.064851726,NA,NA,NA,NA,NA,NA,435,2501,NA,NA,-40.02,NA,617.1,,-0.023033065,0.000340354
511,500,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Financial difficulties,socioeconomic,income,lower,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Self-reported financial difficulties,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.024503065,NA,NA,NA,NA,NA,NA,300,2636,NA,NA,13.19,NA,538.3,,0.007421398,0.000340678
512,501,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Diabetes mellitus,disease,diabetes,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Diabetic status,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.023383568,NA,NA,NA,NA,NA,NA,115,2821,NA,NA,-14.43,NA,617.1,,-0.004536289,0.000340701
513,502,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Social network size (6-10 vs 0–5),psychosocial,social network,less adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,408,both,2358,leukocytes,wbcs,qpcr,0,0,NA,0,positive,SocialNetworkOf6-10.SocialNetworkOf0-5,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.006741209,NA,NA,NA,NA,NA,NA,873,1485,NA,NA,-4.16,NA,617.1,,-0.003255083,0.000424259
514,503,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Lifetime psychiatric disorders,psychiatric,other,none,0-48.1 years,8778.25,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of psychiatric disorders in lifetime,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.096694215,NA,NA,NA,NA,NA,NA,644,2292,NA,NA,-59.67,NA,617.1,,-0.039980416,0.000339627
515,504,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Social network size (more than 10 vs 0–5),psychosocial,social network,less adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,79,both,2029,leukocytes,wbcs,qpcr,0,0,NA,0,positive,SocialNetworkOfMoreThan10.SocialNetworkOf0-5,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.059860638,NA,NA,NA,NA,NA,NA,544,1485,NA,NA,-36.94,NA,617.1,,-0.026507535,0.000492404
516,505,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Respiratory disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Respiratory disease status,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.091897585,NA,NA,NA,NA,NA,NA,252,2684,NA,NA,56.71,NA,617.1,,0.025733315,0.000340264
517,506,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Married or has partner,psychosocial,social network,less adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,3744,both,4972,leukocytes,wbcs,qpcr,0,1,NA,1,negative,MaritalStatus,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.069812372,NA,NA,NA,NA,NA,NA,2936,2036,NA,NA,37.58,NA,538.3,,0.034309345,0.000200693
518,507,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Social network size (6-10 vs 0–5),psychosocial,social network,less adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1130,both,2358,leukocytes,wbcs,qpcr,0,1,NA,0,negative,SocialNetworkOf6-10.SocialNetworkOf0-5,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.005127252,NA,NA,NA,NA,NA,NA,873,1485,NA,NA,2.76,NA,538.3,,0.002475768,0.000424263
519,508,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Lifetime psychiatric disorders,psychiatric,other,none,0-48.1 years,8778.25,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Number of psychiatric disorders in lifetime,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,-0.04770574,NA,NA,NA,NA,NA,NA,644,2292,NA,NA,-25.68,NA,538.3,,-0.019736958,0.00034045
520,509,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Musculoskeletal disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Musculoskeletal disease status,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.007049101,NA,NA,NA,NA,NA,NA,304,2632,NA,NA,-4.35,NA,617.1,,-0.002147615,0.000340712
521,510,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Social network size (more than 10 vs 0–5),psychosocial,social network,less adversity,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,801,both,2029,leukocytes,wbcs,qpcr,0,1,NA,0,negative,SocialNetworkOfMoreThan10.SocialNetworkOf0-5,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.069812372,NA,NA,NA,NA,NA,NA,544,1485,NA,NA,37.58,NA,538.3,,0.030910459,0.000492155
522,511,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Gastrointestinal disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Gastrointestinal disease status,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.131388754,NA,NA,NA,NA,NA,NA,280,2656,NA,NA,-81.08,NA,617.1,,-0.038563108,0.000339703
523,512,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cancer,disease,cancer,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cancer status,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.009204343,NA,NA,NA,NA,NA,NA,203,2733,NA,NA,5.68,NA,617.1,,0.002335089,0.000340712
524,513,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cardiovascular disease,disease,cardiovascular,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Cardiovascular disease status,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.033940182,NA,NA,NA,NA,NA,NA,435,2501,NA,NA,18.27,NA,538.3,,0.012056688,0.000340616
525,514,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Neurological disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Neurological disease status,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.082644628,NA,NA,NA,NA,NA,NA,97,2839,NA,NA,51,NA,617.1,,0.014769975,0.000340567
526,515,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Endocrine (thyroid) disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Endocrine (thyroid) disease status,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.09718036,NA,NA,NA,NA,NA,NA,86,2850,NA,NA,59.97,NA,617.1,,0.016384599,0.000340533
527,516,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Diabetes mellitus,disease,diabetes,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Diabetic status,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.025803455,NA,NA,NA,NA,NA,NA,115,2821,NA,NA,13.89,NA,538.3,,0.005005723,0.000340698
528,517,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Respiratory disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Respiratory disease status,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.108080996,NA,NA,NA,NA,NA,NA,252,2684,NA,NA,-58.18,NA,538.3,,-0.030261181,0.000340092
529,518,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Musculoskeletal disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Musculoskeletal disease status,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.068474828,NA,NA,NA,NA,NA,NA,304,2632,NA,NA,-36.86,NA,538.3,,-0.020857399,0.000340419
530,519,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Gastrointestinal disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,1,positive,Gastrointestinal disease status,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.134497492,NA,NA,NA,NA,NA,NA,280,2656,NA,NA,-72.4,NA,538.3,,-0.03947413,0.000339655
531,520,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Cancer,disease,cancer,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Cancer status,Change in LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.066747167,NA,NA,NA,NA,NA,NA,203,2733,NA,NA,35.93,NA,538.3,,0.01693099,0.00034052
532,521,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Neurological disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Neurological disease status,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.082203232,NA,NA,NA,NA,NA,NA,97,2839,NA,NA,-44.25,NA,538.3,,-0.014691107,0.000340568
533,522,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Endocrine (thyroid) disease,disease,other,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1708,both,2936,leukocytes,wbcs,qpcr,0,1,NA,0,positive,Endocrine (thyroid) disease status,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.021827977,NA,NA,NA,NA,NA,NA,86,2850,NA,NA,-11.75,NA,538.3,,-0.003680664,0.000340706
534,523,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Sleep duration (short vs normal),sleep,less sleep,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,532,both,2482,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ShortSleepers.NormalSleepers,LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.042067736,NA,NA,NA,NA,NA,NA,730,1752,NA,NA,-25.96,NA,617.1,,-0.019164438,0.000402767
535,524,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Sleep duration (long vs normal),sleep,more sleep,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,NA,17556.5,adult,1,adultadult,1950,-90,both,1860,leukocytes,wbcs,qpcr,0,0,NA,0,positive,LongSleepers.NormalSleepers,LTL base pairs,positive,1,dbeta,1,NA,NA,NA,NA,0.028828391,NA,NA,NA,NA,NA,NA,108,1752,NA,NA,17.79,NA,617.1,,0.00674181,0.000537875
536,525,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Sleep duration (short vs normal),sleep,less sleep,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,1254,both,2482,leukocytes,wbcs,qpcr,0,1,NA,0,positive,ShortSleepers.NormalSleepers,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.031766673,NA,NA,NA,NA,NA,NA,730,1752,NA,NA,-17.1,NA,538.3,,-0.014472813,0.000402894
537,526,m,révész2016,révész,2016,Baseline biopsychosocial determinants of telomere length and 6-year attrition rate,homo sapiens,Sleep duration (long vs normal),sleep,more sleep,none,Mean = 48.1 years,17556.5,4927.5,adult,44712.5,unreported,"Participants in the Netherlands Study of Depression and Anxiety (NESDA), a large on-going longitudinal cohort study of 2981 adults (18–65 years).",0,NA,0,17556.5,19746.5,adult,1,adultadult,1228,632,both,1860,leukocytes,wbcs,qpcr,0,1,NA,0,negative,LongSleepers.NormalSleepers,Change in LTL base pairs,negative,1,dbeta,1,NA,NA,NA,NA,-0.126602266,NA,NA,NA,NA,NA,NA,108,1752,NA,NA,-68.15,NA,538.3,,-0.029594921,0.000536982
538,708,m,risques2008,risques,2008,Ulcerative Colitis Is a Disease of Accelerated Colon Aging: Evidence From Telomere Attrition and DNA Damage,homo sapiens,Ulcerative collitis,disease,other,none,50 years,18250,4927.5,adult,44712.5,7592,Unspecified ulcerative collitis patients and controls,0,NA,0,NA,18250,adult,1,adultadult,74,73,both,147,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Ulcerative collitis vs. healthy control,Leucocyte T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.343230043,1.14,1.22,NA,NA,0.23,0.24,102,45,NA,NA,NA,NA,NA,,-0.156245452,0.006518977
539,712,m,rutten2016,rutten,2016,Various mechanistic pathways representing the aging process are altered in COPD,homo sapiens,Smoking (pack-years),smoking,none,none,Around 62 years,22630,4927.5,adult,44712.5,NA,Members of Individualized COPD Evaluation in relation to Ageing (ICE-AGE),0,NA,0,NA,22630,adult,1,adultadult,133,147,both,280,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Pack years of smoking,T/S ratio normalised to never-smoking control group,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.18,NA,NA,NA,NA,,-0.18,0.003355734
540,176,m,saliques2011,saliques,2011,Circulating leukocyte telomere length and oxidative stress: A new target for statin therapy,homo sapiens,Statin use ,medicaltreatment,none,none,Mean age = 66 years,24090,4927.5,adult,44712.5,91.2501,Patients aged >18y & hospitalized <24h after symptom onset for acute MI in the coronary care unit of Dijon University Hospital between 1stMarch & 31st July 2009.,0,NA,0,NA,24090,adult,1,adultadult,69,209,both,278,leukocytes,wbcs,qpcr,0,0,NA,1,negative,StatinUsers.NonStatinUsers,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.363636364,1.25,1.29,NA,NA,0.11,0.11,205,73,NA,NA,NA,NA,NA,,-0.158005005,0.003432102
541,378,m,sampson2006,sampson,2006,Monocyte Telomere Shortening and Oxidative DNA Damage in Type 2 Diabetes,homo sapiens,Type 2 diabetes status (pbmcs),disease,diabetes,none,Mean age = 61.6,22484,"5,110",adult,44712.5,1095,21 male type 2 diabetics and 29 matched controls,0,NA,0,NA,22484,adult,1,adultadult,0,49,male,49,pbmcs,wbcs,flowfish,0,0,NA,1,negative,Diabetics.Controls,PBMC MESF,negative,0,meanssd,1,NA,NA,NA,NA,-0.559419606,7.3,8.9,NA,NA,2.5,3.1,21,28,NA,NA,NA,NA,NA,,-0.266805533,0.017972853
542,379,m,sampson2006,sampson,2006,Monocyte Telomere Shortening and Oxidative DNA Damage in Type 2 Diabetes,homo sapiens,Type 2 diabetes status (naïve t-cells),disease,diabetes,none,Mean age = 61.6,22484,"5,110",adult,44712.5,1095,21 male type 2 diabetics and 29 matched controls,0,NA,0,NA,22484,adult,1,adultadult,0,49,male,49,naïvetcells,wbcs,flowfish,0,0,NA,0,negative,Diabetics.Controls,Naïve t-cell MESF,negative,0,meanssd,1,NA,NA,NA,NA,-0.208610926,8.1,8.7,NA,NA,2.7,3,21,28,NA,NA,NA,NA,NA,,-0.102689872,0.020396266
543,380,m,sampson2006,sampson,2006,Monocyte Telomere Shortening and Oxidative DNA Damage in Type 2 Diabetes,homo sapiens,Type 2 diabetes status (memory t-cells),disease,diabetes,none,Mean age = 61.6,22484,"5,110",adult,44712.5,1095,21 male type 2 diabetics and 29 matched controls,0,NA,0,NA,22484,adult,1,adultadult,0,49,male,49,memory T cells,wbcs,flowfish,0,0,NA,0,negative,Diabetics.Controls,Memory t-cell MESF,negative,0,meanssd,1,NA,NA,NA,NA,-0.148226039,7,7.4,NA,NA,2.4,2.9,21,28,NA,NA,NA,NA,NA,,-0.073156316,0.020610936
544,381,m,sampson2006,sampson,2006,Monocyte Telomere Shortening and Oxidative DNA Damage in Type 2 Diabetes,homo sapiens,Type 2 diabetes status (monocytes),disease,diabetes,none,Mean age = 61.6,22484,"5,110",adult,44712.5,1095,21 male type 2 diabetics and 29 matched controls,0,NA,0,NA,22484,adult,1,adultadult,0,49,male,49,monocytes,wbcs,flowfish,0,0,NA,1,negative,Diabetics.Controls,Monocyte MESF,negative,0,meanssd,1,NA,NA,NA,NA,-1.363636364,4,5.5,NA,NA,1.1,1.1,21,28,NA,NA,NA,NA,NA,,-0.55937319,0.009835597
545,382,sg459,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Separation from parents before 4.1 years of age,psychosocial,traumatic experience,more adversity,0.63-4.1 years,961.775,4927.5,child,44712.5,866.875,"1487 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeparatedFromParentsBefore4.1yrs.NotSeparatedFromParents,Telomere/B-hemoglobin reaction (T/S) ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.055,NA,NA,NA,,-0.055,0.000669333
546,383,sg459,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Separation from parents after 4.1 years of age,psychosocial,traumatic experience,more adversity,4.1-10.13 years,2596.975,4927.5,child,44712.5,866.875,"1488 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeparatedFromParentsAfter4.1yrs.NotSeparatedFromParents,Telomere/B-hemoglobin reaction (T/S) ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.206,NA,NA,NA,,-0.206,0.00061746
547,384,sg459,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Separated from parents for less than 1.4 years,psychosocial,traumatic experience,more adversity,0.63–10.13 years,1963.7,4927.5,child,44712.5,NA,"1489 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,1,negative,SeparatedForLessThan1.4yrs.NotSeparatedFromParents,Telomere/B-hemoglobin reaction (T/S) ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.272,NA,NA,NA,"The IV was length of exposure, so the ""LengthExposure"" variable was recorded as ""NA""",-0.272,0.000577445
548,385,sg459,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Separated from parents for more than 1.4 years,psychosocial,traumatic experience,more adversity,0.63–10.13 years,1963.7,4927.5,child,44712.5,NA,"1490 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeparatedForMoreThan1.4yrs.NotSeparatedFromParents,Telomere/B-hemoglobin reaction (T/S) ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.013,NA,NA,NA,"The IV was length of exposure, so the ""LengthExposure"" variable was recorded as ""NA""",0.063,0.000668066
549,386,m,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Self-reported trauma,psychosocial,traumatic experience,more adversity,0–70.0 years,12775,4927.5,adult,44712.5,unreported,"1491 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,1,adultadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Trauma.NoTrauma,Telomere/B-hemoglobin reaction (T/S) ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.004,NA,NA,NA,,-0.004,0.000673379
550,387,ss221,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Emotional trauma,psychosocial,traumatic experience,more adversity,0–70.0 years,12775,4927.5,adult,44712.5,unreported,"1492 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,1,adultadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,EmotionalTrauma.NoTrauma,Telomere/B-hemoglobin reaction (T/S) ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.011,NA,NA,NA,,0.061,0.000668399
551,388,ss221,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Trauma before 10 years of age,psychosocial,traumatic experience,more adversity,0-10 years,1825,4927.5,child,44712.5,unreported,"1494 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,TraumaBefore10yrsAge.NoTrauma,Telomere/B-hemoglobin reaction (T/S) ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.033,NA,NA,NA,,-0.033,0.000671935
552,389,ss221,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Trauma after 10 years of age,psychosocial,traumatic experience,more adversity,10-70 years,14600,4927.5,adult,44712.5,unreported,"1495 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,1,adultadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,TraumaAfter10yrsAge.NoTrauma,Telomere/B-hemoglobin reaction (T/S) ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.051,NA,NA,NA,,0.101,0.000659732
553,390,m,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Separation from parents in childhood,psychosocial,traumatic experience,more adversity,Median age at separation = 4.1 years,1496.5,4927.5,child,44712.5,866.875,"1486 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,0,childadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeparatedFromParents.NotSeparatedFromParents,Telomere/B-hemoglobin reaction (T/S) ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.134328844,78.3,81.5,NA,NA,25.1,23.6,215,1271,NA,NA,NA,NA,NA,,-0.047201753,0.000670403
554,391,ss221,savolainen2014a,savolainen,2014a,"Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults",homo sapiens,Physical trauma,psychosocial,traumatic experience,more adversity,0–70.0 years,12775,4927.5,adult,44712.5,unreported,"1493 participants (674 men, 812 women), from the Helsinki Birth Cohort Study (HBCS).",0,NA,0,NA,23761.5,adult,1,adultadult,812,674,both,1486,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PhysicalTrauma.NoTrauma,Telomere/B-hemoglobin reaction (T/S) ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,NA,NA,NA,,0.05,0.000670038
555,682,m,savolainen2014b,savolainen,2014b,The history of sleep apnea is associated with shorter leukocyte telomere length: The Helsinki Birth Cohort Study,homo sapiens,Sleep apnea,disease,sleep apnea,none,Approx 61.5 years,22447.5,4927.5,adult,44712.5,2190,Members of Helsinki Birth Cohort study,0,NA,0,NA,22447.5,adult,1,adultadult,1046,902,both,1948,leukocytes,wbcs,qpcr,0,0,NA,1,negative,History of sleep apnea,Leucocyte T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.375,NA,NA,NA,,-0.375,0.000379315
556,284,m,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Childhood trauma index,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood trauma index,LTL bp,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.015022222,-2.73,2.08,378,,-0.015022222,0.00201929
557,285,m,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Childhood adverse events,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Childhood adverse events,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.211322751,NA,NA,NA,NA,NA,NA,116,380,NA,NA,-79.88,NA,378,,-0.089095298,0.001988257
558,286,m,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Negative recent life events (past five years),psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Negative recent life events (past five years),LTL bp,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.013757407,3.91,1.33,378,,0.063757407,0.002003811
559,287,m,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Loneliness,psychosocial,social network,more adversity,60–93 years old,27922.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Loneliness,LTL bp,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.023548148,-2.38,3.74,378,,-0.023548148,0.002017962
560,288,ss284,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Emotional neglect,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,EmotionalNeglect.NoEmotionalNeglect,LTL bp,positive,1,dbeta,1,NA,NA,NA,NA,0.000449735,NA,NA,NA,NA,NA,NA,162,334,NA,NA,0.17,NA,378,,0.000210914,0.002020202
561,289,ss284,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Psychological abuse,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PsychologicalAbuse.NoPsychologicalAbuse,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.067301587,NA,NA,NA,NA,NA,NA,105,391,NA,NA,-25.44,NA,378,,-0.027482902,0.002017151
562,290,ss284,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Physical abuse,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,PhysicalAbuse.NoPhysicalAbuse,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.035873016,NA,NA,NA,NA,NA,NA,61,435,NA,NA,-13.56,NA,378,,-0.011780551,0.002019641
563,291,ss284,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Sexual abuse,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SexualAbuse.NoSexualAbuse,LTL bp,positive,1,dbeta,1,NA,NA,NA,NA,0.055449735,NA,NA,NA,NA,NA,NA,90,406,NA,NA,20.96,NA,378,,0.021365002,0.002018358
564,292,ss285,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Parental divorce,psychosocial,other negative,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ParentalDivorce.NoParentalDivorce,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.276402116,NA,NA,NA,NA,NA,NA,28,468,NA,NA,-104.48,NA,378,,-0.063661927,0.00200386
565,293,ss285,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Separation from parents,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,SeparationFromParents.NoSeparationFromParents,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.269417989,NA,NA,NA,NA,NA,NA,48,448,NA,NA,-101.84,NA,378,,-0.079401949,0.001994809
566,294,ss285,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Parental death,psychosocial,traumatic experience,more adversity,0-16 years,2920,4927.5,child,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,0,childadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,ParentalDeath.NoParentalDeath,LTL bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.014206349,NA,NA,NA,NA,NA,NA,60,436,NA,NA,-5.37,NA,378,,-0.004632496,0.002020115
567,295,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Seriously ill/wounded/victim of violence,psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Seriously ill/wounded/victim of violence.Controls,LTL bp,negative,1,ttest,1,NA,NA,-2.21,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.099243525,0.001980603
568,296,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Seriously ill/wounded/victim of violence (family member),psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Seriously ill/wounded/victim of violence (family member).Controls,LTL bp,negative,1,ttest,1,NA,NA,-0.27,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.012184025,0.002019602
569,297,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,"Parent, child, brother or sister died",psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Parent, child, brother or sister died.Controls",LTL bp,positive,1,ttest,1,NA,NA,0.49,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.022107986,0.002018228
570,298,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Friend or family member died,psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Friend or family member died.Controls,LTL bp,positive,1,ttest,1,NA,NA,0.72,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.032476006,0.002015943
571,299,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Friendship with a close friend/family member ended,psychosocial,traumatic experience,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Friendship with a close friend/family member ended.Controls,LTL bp,positive,1,ttest,1,NA,NA,2,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.089893315,0.001987684
572,300,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Serious problem with close friend/family member/neighbor,psychosocial,other negative,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Serious problem with close friend/family member/neighbor.Controls,LTL bp,positive,1,ttest,1,NA,NA,1.77,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.079625355,0.001994666
573,301,ss286,schaakxs2016,schaakxs,2016,Early and recent psychosocial stress and telomere length in older adults,homo sapiens,Something worthwhile or money was stolen or lost,psychosocial,other negative,more adversity,55-88 years old,26097.5,4927.5,adult,44712.5,unreported,"NESDO sample of 510 older adults (60–93 years old) with either a DSM-IV based depressive disorder depression or dysthymia (6-month recency)) or no lifetime diagnosis of depression, determined using the CIDI.",0,NA,0,NA,27922.5,adult,1,adultadult,323,173,both,496,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Something worthwhile or money was stolen or lost.Controls,LTL bp,negative,1,ttest,1,NA,NA,-0.31,491,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.013988735,0.002019411
574,314,ss313,shalev2012,shalev,2012,Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study,homo sapiens,Violence exposure measured with the Conflict Tactics Scale (1 exposure),psychosocial,traumatic experience,more adversity,5 years,1825,4927.5,child,44712.5,unreported,A subsample of members of the Environmental-Risk (E-Risk) Study.,0,NA,0,1825,3650,child,1,childchild,97,100,both,197,buccal,buccal,qpcr,0,0,NA,unreported,negative,1ViolenceExposure.None,Buccal cell telomere length (T/S ratio),negative,1,meansse,1,NA,NA,NA,NA,-0.128642585,0.95,0.99,0.03,0.03,0.249198716,0.339411255,69,128,NA,NA,NA,NA,NA,"This study was longitudinal but, because changes were reported in betas of unknown status, only the cross-sectional meanssd effects could be used.",-0.061253625,0.005063827
575,315,ss313,shalev2012,shalev,2012,Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study,homo sapiens,Violence exposure measured with the Conflict Tactics Scale (Domestic violence exposure),psychosocial,traumatic experience,more adversity,5 years,1825,4927.5,child,44712.5,unreported,A subsample of members of the Environmental-Risk (E-Risk) Study.,0,NA,0,1825,3650,child,1,childchild,84,84,both,168,buccal,buccal,qpcr,0,0,NA,unreported,negative,DomesticViolence.None,Buccal cell telomere length (T/S ratio),negative,1,meansse,1,NA,NA,NA,NA,-0.239442718,0.91,0.99,0.05,0.03,0.316227766,0.339411255,40,128,NA,NA,NA,NA,NA,"This study was longitudinal but, because changes were reported in betas of unknown status, only the cross-sectional meanssd effects could be used.",-0.101456658,0.005865384
576,316,ss313,shalev2012,shalev,2012,Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study,homo sapiens,Violence exposure measured with the Conflict Tactics Scale (Bullying exposure),psychosocial,traumatic experience,more adversity,5 years,1825,4927.5,child,44712.5,unreported,A subsample of members of the Environmental-Risk (E-Risk) Study.,0,NA,0,1825,3650,child,1,childchild,89,96,both,185,buccal,buccal,qpcr,0,0,NA,unreported,negative,Bullying.None,Buccal cell telomere length (T/S ratio),negative,1,meansse,1,NA,NA,NA,NA,-0.274044369,0.9,0.99,0.04,0.03,0.301993377,0.339411255,57,128,NA,NA,NA,NA,NA,"This study was longitudinal but, because changes were reported in betas of unknown status, only the cross-sectional meanssd effects could be used.",-0.125528587,0.005264856
577,317,ss313,shalev2012,shalev,2012,Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study,homo sapiens,Violence exposure measured with the Conflict Tactics Scale (Physical maltreatment),psychosocial,traumatic experience,more adversity,5 years,1825,4927.5,child,44712.5,unreported,A subsample of members of the Environmental-Risk (E-Risk) Study.,0,NA,0,1825,3650,child,1,childchild,91,100,both,191,buccal,buccal,qpcr,0,0,NA,unreported,negative,PhysicalMaltreatment.None,Buccal cell telomere length (T/S ratio),negative,1,meansse,1,NA,NA,NA,NA,-0.330946917,0.88,0.99,0.04,0.03,0.317490157,0.339411255,63,128,NA,NA,NA,NA,NA,"This study was longitudinal but, because changes were reported in betas of unknown status, only the cross-sectional meanssd effects could be used.",-0.153746649,0.005017277
578,313,m,shalev2012,shalev,2012,Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study,homo sapiens,Violence exposure measured with the Conflict Tactics Scale (2+ exposures),psychosocial,traumatic experience,more adversity,5 years,1825,4927.5,child,44712.5,unreported,A subsample of members of the Environmental-Risk (E-Risk) Study.,0,NA,0,1825,3650,child,1,childchild,116,51,both,167,buccal,buccal,qpcr,0,0,NA,unreported,negative,2+ViolenceExposures.None,Buccal cell telomere length (T/S ratio),negative,1,meansse,1,NA,NA,NA,NA,-0.449974639,0.84,0.99,0.05,0.03,0.3122499,0.339411255,39,128,NA,NA,NA,NA,NA,"This study was longitudinal but, because changes were reported in betas of unknown status, only the cross-sectional meanssd effects could be used.",-0.187015741,0.005610081
579,340,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Childhood maltreatment,psychosocial,traumatic experience,more adversity,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood maltreatment,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.032,NA,NA,NA,NA,,-0.032,0.002387447
580,341,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Lifetime cigarette consumption (pack-year) up to age 38 years,smoking,none,none,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Lifetime cigarette consumption,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.105,NA,NA,NA,NA,,-0.105,0.002339884
581,342,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Substance dependence disorders from age 18 to 38,other,other,none,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Substance dependence disorders,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.092,NA,NA,NA,NA,,-0.092,0.002352018
582,343,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Psychiatric medication use from age 20 to 38 years,psychiatric,other,none,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Psychiatric medication use ,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.019,NA,NA,NA,NA,,-0.019,0.002390618
583,344,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Physical health problem index at age 38 years,disease,other,none,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Physical health problems,LTL (T/S ratio),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.135,NA,NA,NA,NA,,-0.135,0.002305938
584,345,m,shalev2014,shalev,2014,"Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder",homo sapiens,Adult SES at age 38 years,socioeconomic,composite measure,higher,38,13870,"5,110",adult,44712.5,unreported,419 men - a subsample of the Dunedin Cohort,0,NA,0,NA,13870,adult,1,adultadult,0,419,male,419,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Adult SES,LTL (T/S ratio),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.051,NA,NA,NA,NA,,0.051,0.002379916
585,346,m,shan2014,shan,2014,"A feasibility study of the association of exposure to biomass smoke with vascular function, inflammation, and cellular aging",homo sapiens,Integrated 24-hour personal exposure to fine particulate matter,environmentalhazard,none,none,38–85 years,21535,"4,745",adult,44712.5,unreported,"Never-smoking women from Shiyi Village, Sichuan Province, who were not pregnant & primarily used biomass fuel for cooking.",0,NA,0,NA,21535,adult,1,adultadult,23,0,female,23,buccal,buccal,qpcr,0,0,NA,0,negative,LowPM25exposure.HighPM25exposure,Log-transformed buccal cell T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.596028129,3.3,5.4,NA,NA,2.3,4.5,12,11,NA,NA,NA,NA,NA,"Although they say they log transformed ts ratio for analysis, the numbers in table 3 look like the untransformed numbers.",-0.285353264,0.038353514
586,629,m,shen2009,shen,2009,"Telomere length, oxidative damage, antioxidants and breast cancer risk",homo sapiens,Breast cancer vs. control,disease,cancer,none,Unreported adults,unreported,"4,745",adult,44712.5,unreported,Members of Long Island Breast Cancer Study Project (LIBCSP) and controls,0,NA,0,NA,Unreported adults,adult,1,adultadult,2169,0,female,2169,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Breast cancer patient vs. control,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.019602733,1.03,1.05,NA,NA,1.01,1.03,1061,1108,NA,NA,NA,NA,NA,,-0.009798595,0.000461166
587,630,m,shen2012,shen,2012,Association of leukocyte telomere length with type 2 diabetes in mainland Chinese populations,homo sapiens,Diabetes status,disease,diabetes,none,Mean age = 61 years,22265,4927.5,adult,44712.5,unreported,"4016 Chinese Han participants were recruited from Shanghai, China; these comprised 1936 unrelated T2D cases and 2080 controls.",?,ma2013,1,NA,22265,adult,1,adultadult,2592,1424,both,4016,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Diabetics.Controls,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.17380446,0.98,1.04,NA,NA,0.34,0.35,1936,2080,NA,NA,NA,NA,NA,,-0.086520678,0.000245351
588,310,ss311,shin2008,shin,2008,Exercise training improves the antioxidant enzyme activity with no changes of telomere length,homo sapiens,Exercise intervention (3 days per week for 6 months),physicalactivity,more activity,none,Mean age = 46.81,17085.65,"4,745",adult,44712.5,182.5,"Sixteen obese middle-aged women (age: 46.81   6.43 years, BMI: 28.55+/-2.80 kg/m2)",1,shin2008,0,17085.65,17268.15,adult,1,adultadult,16,0,female,16,leukocytes,wbcs,qpcr,1,1,reduce,0,negative,ExerciseIntervention.Controls,Decrease in wbc telomere length (T/S ratio) ,positive,0,meanssd,1,NA,NA,NA,NA,0.165883903,0.0144,3.00E-04,NA,NA,0.1202,0.0013,8,8,NA,NA,NA,NA,NA,"This is the same effect as 311, but using qpcr, rather than southern blot.",0.082658121,0.065758797
589,311,m,shin2008,shin,2008,Exercise training improves the antioxidant enzyme activity with no changes of telomere length,homo sapiens,Exercise intervention (3 days per week for 6 months),physicalactivity,more activity,none,Mean age = 46.81,17085.65,"4,745",adult,44712.5,182.5,"Sixteen obese middle-aged women (age: 46.81   6.43 years, BMI: 28.55+/-2.80 kg/m2)",0,NA,0,17085.65,17268.15,adult,1,adultadult,16,0,female,16,leukocytes,wbcs,southernblot,1,1,reduce,0,negative,ExerciseIntervention.Controls,Decrease in wbc telomere length (bp) ,positive,0,meanssd,1,NA,NA,NA,NA,0.533871457,42.5,16.25,NA,NA,65.53,23.26,8,8,NA,NA,NA,NA,NA,,0.257905343,0.058092929
590,529,m,shlush2011,shlush,2011,"Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress - Implications for tissue and organismal aging",homo sapiens,Closed circuit oxygen rebreathing diving vs. control,other,other,none,19 years,6935,"5,110",adult,44712.5,365,Members of the Israeli Defence forces undergoing diver training,0,NA,0,6935,7300,adult,1,adultadult,0,29,male,29,granulocytes,wbcs,flowfish,0,1,NA,0,negative,Diving exposure,Change in mean TL in kbp,positive,0,meanssd,1,NA,NA,NA,NA,0.244677262,0.6,0.5,NA,NA,0.5,0.3,14,15,NA,NA,NA,NA,NA,,0.121362122,0.034669979
591,530,m,shlush2011,shlush,2011,"Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress - Implications for tissue and organismal aging",homo sapiens,Closed circuit oxygen rebreathing diving vs. control,other,other,none,19 years,6935,"5,110",adult,44712.5,365,Members of the Israeli Defence forces undergoing diver training,0,NA,0,6935,7300,adult,1,adultadult,0,29,male,29,naïve T cells,wbcs,flowfish,0,1,NA,1,negative,Diving exposure,Change in mean TL in kbp,negative,0,meanssd,1,NA,NA,NA,NA,-0.766666667,-0.2,0.03,NA,NA,0.3,0.3,14,15,NA,NA,NA,NA,NA,,-0.357750395,0.027157484
592,531,m,shlush2011,shlush,2011,"Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress - Implications for tissue and organismal aging",homo sapiens,Closed circuit oxygen rebreathing diving vs. control,other,other,none,19 years,6935,"5,110",adult,44712.5,365,Members of the Israeli Defence forces undergoing diver training,0,NA,0,6935,7300,adult,1,adultadult,0,29,male,29,memory T cells,wbcs,flowfish,0,1,NA,1,negative,Diving exposure,Change in mean TL in kbp,positive,0,meanssd,1,NA,NA,NA,NA,0.6,-0.02,-0.2,NA,NA,0.3,0.3,14,15,NA,NA,NA,NA,NA,,0.287191096,0.030065903
593,532,m,shlush2011,shlush,2011,"Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress - Implications for tissue and organismal aging",homo sapiens,Closed circuit oxygen rebreathing diving vs. control,other,other,none,19 years,6935,"5,110",adult,44712.5,365,Members of the Israeli Defence forces undergoing diver training,0,NA,0,6935,7300,adult,1,adultadult,0,29,male,29,B cells,wbcs,flowfish,0,1,NA,0,negative,Diving exposure,Change in mean TL in kbp,negative,0,meanssd,1,NA,NA,NA,NA,-0.575641934,-0.08,0.1,NA,NA,0.4,0.2,14,15,NA,NA,NA,NA,NA,,-0.276440392,0.030464333
594,642,m,simon2006,simon,2006,Telomere Shortening and Mood Disorders: Preliminary Support for a Chronic Stress Model of Accelerated Aging,homo sapiens,Mood disorder vs. control,psychiatric,depression and anxiety,depression,50.8 years (8.0),18542,4927.5,adult,44712.5,11607,Mood disorder patients and healthy controls from Massachussetts,0,NA,0,NA,18542,adult,1,adultadult,40,48,both,88,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Any mood disorder vs. healthy control,TL in kilobase pairs,negative,0,meanssd,1,NA,NA,3.16,86,-0.674382853,6.98,7.64,NA,NA,0.84,1.1,44,44,NA,NA,NA,NA,NA,,-0.319516134,0.009267142
595,548,m,simon2015,simon,2015,Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls,homo sapiens,Depression (diagnosis of MDD),psychiatric,depression and anxiety,depression,41.3 years (13.7),15074.5,4927.5,adult,44712.5,4599,Patients from Massachusetts General Hospital and controls,0,NA,0,NA,15074.5,adult,1,adultadult,178,154,both,332,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Diagnosis of MDD (southern blot),log(Mean telomere length kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.072428597,8.9,9.1,NA,NA,3,2.5,166,166,NA,NA,NA,NA,NA,,-0.036190575,0.003013239
596,549,m,simon2015,simon,2015,Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls,homo sapiens,Depression (diagnosis of MDD),psychiatric,depression and anxiety,depression,41.3 years (13.7),15074.5,4927.5,adult,44712.5,4599,Patients from Massachusetts General Hospital and controls,0,NA,0,NA,15074.5,adult,1,adultadult,178,154,both,332,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Diagnosis of MDD (qpcr),Log transformed T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.052342392,0.64,0.65,NA,NA,0.17,0.21,166,166,NA,NA,NA,NA,NA,,-0.026162238,0.003017014
597,709,m,smearman2016,smearman,2016,Variation in the oxytocin receptor gene moderates the protective effects of a family-based prevention program on telomere length,homo sapiens,Socioeconomic risk,socioeconomic,composite measure,lower,22 years,8030,4927.5,adult,44712.5,unreported,African-American youth participating in the Adults In The Making trial,0,NA,0,NA,8030,adult,1,adultadult,unreported,unreported,both,191,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Socioeconomic risk,Lymphocyte T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.023,NA,NA,NA,,0.073,0.005207213
598,710,m,smearman2016,smearman,2016,Variation in the oxytocin receptor gene moderates the protective effects of a family-based prevention program on telomere length,homo sapiens,Non-supportive parenting,parentalcare,less parental care,none,22 years,8030,4927.5,adult,44712.5,unreported,African-American youth participating in the Adults In The Making trial,0,NA,0,NA,8030,adult,1,adultadult,unreported,unreported,both,191,lymphocytes,wbcs,qpcr,0,0,NA,0,negative,Non-supportive parenting,Lymphocyte T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.131,NA,NA,NA,,-0.131,0.005084066
599,711,m,smearman2016,smearman,2016,Variation in the oxytocin receptor gene moderates the protective effects of a family-based prevention program on telomere length,homo sapiens,AIM intervention (family-based skills intervention with life stress),parentalcare,more parental care,none,22 years,8030,4927.5,adult,44712.5,1825,African-American youth participating in the Adults In The Making trial,0,NA,0,NA,8030,adult,1,adultadult,unreported,unreported,both,191,lymphocytes,wbcs,qpcr,1,0,NA,0,positive,AIM intervention (family-based skills intervention with life stress),Lymphocyte T/S ratio,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.112,NA,NA,NA,,0.162,0.00499053
600,562,m,snetselaar2015,snetselaar,2015,Telomere length in interstitial lung diseases,homo sapiens,Interstitial lung disease,disease,other,none,Median approx 49 years,17885,4927.5,adult,44712.5,unreported,Interstitial lung disease patients and controls from hospital in the Netherlands,0,NA,0,NA,17885,adult,1,adultadult,363,202,both,532,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Diagnosis of interstitial lung disease vs. control,T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-1.17,0.858,0.975,NA,NA,0.1,0.1,359,173,NA,NA,NA,NA,NA,Paper is internally inconsistent about numbers of males and females and total numbers.,-0.480626028,0.00111367
601,655,m,sohn2012,sohn,2012,"Telomeric DNA quantity, DNA damage, and heat shock protein gene expression as physiological stress markers in chickens",gallus gallus,Experimental stress (high stocking density and food restriction),other,other,,62 to 64 weeks,22995,unavailable,adult,10950,14,Single comb white leghorn chickens,0,NA,NA,434,448,adult,1,adultadult,56,0,female,56,lymphocytes,wbcs,qfish,1,1,induce,1,positive,Experimental stress consisting of high stocking density and food restriction to 75% ad lib,Shortening rate of erythrocyte telomeres over course of manipulation (rel quanitity of telomeric DNA),negative,0,meanssd,1,NA,NA,NA,NA,2.928024464,0.169,-0.048,NA,NA,0.083,0.064,28,28,NA,NA,NA,NA,NA,,0.825751918,0.001840165
602,656,x655,sohn2012,sohn,2012,"Telomeric DNA quantity, DNA damage, and heat shock protein gene expression as physiological stress markers in chickens",gallus gallus,Experimental stress (high stocking density and food restriction),other,other,,62 to 64 weeks,22995,unavailable,adult,10950,14,Single comb white leghorn chickens,0,NA,NA,434,448,adult,1,adultadult,56,0,female,56,lymphocytes,wbcs,qfish,1,0,induce,1,negative,Experimental stress consisting of high stocking density and food restriction to 75% ad lib,Rel quanitity of telomeric DNA at the end of the manipulation (lymphocytes),negative,0,meanssd,1,NA,NA,NA,NA,-0.765330187,1.21,1.49,NA,NA,0.34,0.39,28,28,NA,NA,NA,NA,NA,,-0.357391804,0.013833761
603,657,m,sohn2012,sohn,2012,"Telomeric DNA quantity, DNA damage, and heat shock protein gene expression as physiological stress markers in chickens",gallus gallus,Experimental stress (high stocking density and food restriction),other,other,,62 to 64 weeks,22995,unavailable,adult,10950,14,Single comb white leghorn chickens,0,NA,NA,434,448,adult,1,adultadult,56,0,female,56,liver,other,qfish,1,0,induce,0,negative,Experimental stress consisting of high stocking density and food restriction to 75% ad lib,Rel quanitity of telomeric DNA at the end of the manipulation (liver),positive,0,meanssd,1,NA,NA,NA,NA,0,1.41,1.41,NA,NA,0.2,0.25,28,28,NA,NA,NA,NA,NA,,0,0.018181818
604,658,m,sohn2012,sohn,2012,"Telomeric DNA quantity, DNA damage, and heat shock protein gene expression as physiological stress markers in chickens",gallus gallus,Experimental stress (high stocking density and food restriction),other,other,,62 to 64 weeks,22995,unavailable,adult,10950,14,Single comb white leghorn chickens,0,NA,NA,434,448,adult,1,adultadult,56,0,female,56,spleen,other,qfish,1,0,induce,0,negative,Experimental stress consisting of high stocking density and food restriction to 75% ad lib,Rel quanitity of telomeric DNA at the end of the manipulation (spleen),negative,0,meanssd,1,NA,NA,NA,NA,-0.273254867,2.15,2.31,NA,NA,0.61,0.56,28,28,NA,NA,NA,NA,NA,,-0.135369798,0.017521561
605,525,m,soler2015,soler,2015,Telomere dynamics in parasitic great spotted cuckoos and their magpie hosts,pica pica,Laying date,other,other,,1 day,1,730,juvenile,7920.5,18,Magpies in nests parasitised by cuckoos,0,NA,NA,NA,1,juvenile,1,juvenilejuvenile,unreported,unreported,both ,26,rbcs,rbcs,qpcr,0,0,NA,1,negative,Laying date,NRQ (normalised relative quantities),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.44,NA,NA,NA,NA,,-0.44,0.026011238
606,526,m,soler2015,soler,2015,Telomere dynamics in parasitic great spotted cuckoos and their magpie hosts,pica pica,Laying date,other,other,,18 days,18,730,juvenile,7920.5,18,Magpies in nests parasitised by cuckoos,0,NA,NA,1,18,juvenile,1,juvenilejuvenile,unreported,unreported,both ,26,rbcs,rbcs,qpcr,0,1,NA,1,positive,Laying date,NRQ (normalised relative quantities),negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.53,NA,NA,NA,NA,,-0.53,0.020684192
607,527,m,soler2015,soler,2015,Telomere dynamics in parasitic great spotted cuckoos and their magpie hosts,clamator glandarius,Laying date,other,other,,1 day,1,unavailable,juvenile,unavailable,16,Great spotted cuckoos in magpie nests,0,NA,NA,NA,1,juvenile,1,juvenilejuvenile,unreported,unreported,both ,18,rbcs,rbcs,qpcr,0,0,NA,1,negative,Laying date,NRQ (normalised relative quantities),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.49,NA,NA,NA,NA,,0.49,0.03396753
608,528,m,soler2015,soler,2015,Telomere dynamics in parasitic great spotted cuckoos and their magpie hosts,clamator glandarius,Laying date,other,other,,16 days,16,unavailable,juvenile,unavailable,16,Great spotted cuckoos in magpie nests,0,NA,NA,1,18,juvenile,1,juvenilejuvenile,unreported,unreported,both ,16,rbcs,rbcs,qpcr,0,1,NA,0,positive,Laying date,NRQ (normalised relative quantities),positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.44,NA,NA,NA,NA,,0.44,0.043352064
609,563,m,stefanidis2015,stefanidis,2015,Telomere Length in Peripheral Blood Mononuclear Cells of Patients on Chronic Hemodialysis Is Related With Telomerase Activity and Treatment Duration,homo sapiens,Hemodialysis,medicaltreatment,none,none,65 years,23725,4927.5,adult,44712.5,605.291667,Patients on chronic hemodialysis and healthy controls from hospital in Greece,0,NA,0,NA,23725,adult,1,adultadult,34,32,both,66,pbmcs,wbcs,southernblot,0,0,NA,0,negative,Chronic hemodialysis patient vs. control,Mean TRF in kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.125319275,6.95,7.31,NA,NA,3.25,1.96,43,23,NA,NA,NA,NA,NA,,-0.059607263,0.015275486
610,564,sg563,stefanidis2015,stefanidis,2015,Telomere Length in Peripheral Blood Mononuclear Cells of Patients on Chronic Hemodialysis Is Related With Telomerase Activity and Treatment Duration,homo sapiens,Hemodialysis,medicaltreatment,none,none,65 years,23725,4927.5,adult,44712.5,NA,Patients on chronic hemodialysis from hospital in Greece,0,NA,0,NA,23725,adult,1,adultadult,17,26,both,43,pbmcs,wbcs,southernblot,0,0,NA,1,negative,Duration of hemodialysis,Mean TRF in kb,negative,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.332,NA,NA,NA,NA,,-0.332,0.018850032
611,497,m,stier2014,stier,2014,Starting with a handicap: Phenotypic differences between early- and late-born king penguin chicks and their survival correlates,aptenodytes patagonicus,Being late hatched rather than early hatched,other,other,,10 days,10,unavailable,juvenile,9490,10,84 king penguin chicks,0,NA,NA,NA,10,juvenile,1,juvenilejuvenile,unreported,unreported,both ,84,rbcs,rbcs,qpcr,0,0,NA,1,negative,Being late versus early hatched,T/S ratio,negative,0,meansse,1,NA,NA,NA,NA,-0.537943889,1.11,1.44,0.09,0.1,0.603738354,0.6244998,45,39,NA,NA,NA,NA,NA,,-0.259121567,0.010484582
612,312,m,sudyka2014,sudyka,2014,Experimentally increased reproductive effort alters telomere length in the blue tit (Cyanistes caeruleus),cyanistes caeruleus,Experimental manipulation of parenting effort by brood enlargement (+3 nestlings),socioeconomic,income,,Mean age = 1 year,365,365,adult,5329,20,Wild population of nest-box breeding blue tits inhabiting the southern part of the Baltic island of Gotland,0,NA,NA,379,744,adult,1,adultadult,20,36,both,56,rbcs,rbcs,qpcr,1,1,induce,1,positive,IncreasedParentingLoad.ControlNests,Change in erythrocyte telomere length (T/S ratio),negative,1,fanova,1,4.827,47.808,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,Direction of effect was such that parents of enlarged broods experienced more telomere shortening.,0.302831701,0.014999929
613,363,m,surtees2011,surtees,2011,"Life Stress, Emotional Health, and Mean Telomere Length in the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study",homo sapiens,Self-reported impact of stressful events experienced,psychosocial,stress,more adversity,41-80 years,22082.5,"4,745",adult,44712.5,unreported,"An ethnically homogeneous population of 4,441 women, aged 41–80 years from the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study",0,NA,0,NA,22082.5,adult,1,adultadult,"4,441",0,female,4441,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Impact of stressful events,Leukocyte ?Ct,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.005,NA,NA,NA,,-0.005,0.000225214
614,364,m,surtees2011,surtees,2011,"Life Stress, Emotional Health, and Mean Telomere Length in the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study",homo sapiens,Self-reported trouble in adapting to stressful events experienced,psychosocial,stress,more adversity,41-80 years,22082.5,"4,745",adult,44712.5,unreported,"An ethnically homogeneous population of 4,441 women, aged 41–80 years from the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study",0,NA,0,NA,22082.5,adult,1,adultadult,"4,441",0,female,4441,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Trouble in adapting to stressful events,Leukocyte ?Ct,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.002,NA,NA,NA,,-0.002,0.000225223
615,221,m,tanrikulu-kucuk2012,tanrikulu-kucuk,2012,Dietary restriction of amino acids other than methionine prevents oxidative damage during aging: Involvement of telomerase activity and telomere length,rattus norvegicus,Amino acid restriction in younger rats,nutrition,protein,,4-8 months,180,70,adult,1387,122,30 4-month old male wistar rats,0,NA,NA,NA,180,adult,1,adultadult,0,30,male,30,liver,other,southernblot,1,0,reduce,0,positive,NormalDiet.RestrictedAminoAcids,Liver TL in kb,negative,0,meanssd,1,NA,NA,NA,NA,0.293820613,30.1,27.93,NA,NA,9,5.3,15,15,NA,NA,NA,NA,NA,,0.14535016,0.033041138
616,222,m,tanrikulu-kucuk2012,tanrikulu-kucuk,2012,Dietary restriction of amino acids other than methionine prevents oxidative damage during aging: Involvement of telomerase activity and telomere length,rattus norvegicus,Amino acid restriction in older rats,nutrition,protein,,12-16 months,420,70,adult,1387,122,30 12-month old male wistar rats,0,NA,NA,NA,420,adult,1,adultadult,0,30,male,30,liver,other,southernblot,1,0,reduce,1,positive,NormalDiet.RestrictedAminoAcids,Liver TL in kb,positive,0,meanssd,1,NA,NA,NA,NA,-0.571174298,19,23.08,NA,NA,5.3,8.6,15,15,NA,NA,NA,NA,NA,,-0.274608103,0.029478186
617,653,m,teyssier2014,teyssier,2014,Telomeres in the brain cortex of patients with major depressive disorder,homo sapiens,Depression,psychiatric,depression and anxiety,depression,43.66666667,15938.33333,4927.5,adult,44712.5,4745,Post-mortem samples from Stanley Medical Research Institute,0,NA,0,NA,15938.33333,adult,1,adultadult,unreported,unreported,both,36,cerebral cortex,other,qpcr,0,0,NA,0,negative,Depression versus control,T/S ratio (described as Ct ratio),positive,0,meansse,1,NA,NA,NA,NA,0,0.79,0.79,0.001,0.001,0.004898979,0.003464102,24,12,NA,NA,NA,NA,NA,,0,0.028571429
618,389,m,theall2013,theall,2013,Neighborhood disorder and telomeres: Connecting children’s exposure to community level stress and cellular response,homo sapiens,"Perceived neighborhood disorder (based on Sampson & Morenoff, 2004) - a summary score of caregiver report of the presence or absence of seven items surrounding the child’s home: 1) garbage, litter, or broken glass, 2) graffiti, 3) vacant, abandoned, or boarded-up buildings, 4) abandoned vehicles, 5) broken steps, 6) broken glass or broken toys, and 7) the presence of strewn garbage/litter immediately outside the child’s home.",psychosocial,other negative,more adversity,4-14 years,3285,4927.5,child,44712.5,1032.4,"199 children (1 per household) aged 4-14 and their families recruited in 2010 through local elementary and middle schools in New Orleans, Louisiana",0,NA,0,NA,3285,child,1,childchild,55,49,both,104,saliva,buccal,qpcr,0,0,NA,1,negative,Perceived neighbourhood disorder,Saliva telomere length (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.478,NA,NA,NA,,-0.478,0.005778999
619,390,m,theall2013,theall,2013,Neighborhood disorder and telomeres: Connecting children’s exposure to community level stress and cellular response,homo sapiens,Economic deprivation: percentage of families in neighbourhood below poverty line,socioeconomic,income,lower,4-14 years,3285,4927.5,child,44712.5,1032.4,"199 children (1 per household) aged 4-14 and their families recruited in 2010 through local elementary and middle schools in New Orleans, Louisiana",0,NA,0,NA,3285,child,1,childchild,55,49,both,104,saliva,buccal,qpcr,0,0,NA,1,negative,Percent of familes below poverty line in neighbourhood,Saliva telomere length (T/S ratio),negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.01,NA,NA,NA,,-0.01,0.009706796
620,280,m,tomiyama2012,tomiyama,2012,Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length.,homo sapiens,Caregiver status,psychosocial,caregiving,more adversity,Mean age = 62 years,22630,"4,745",adult,44712.5,unreported,Twenty-three postmenopausal women comprising caregivers for dementia partners (n=14) and age- and BMI-matched noncaregivers,0,NA,0,NA,22630,adult,1,adultadult,23,0,female,23,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Caregivers.noncaregivers,PBMC bp,Reference group unclear,1,dbeta,1,NA,NA,NA,NA,0.007796652,NA,NA,NA,NA,NA,NA,14,9,NA,NA,4.42,NA,566.91,"All dbetas were from models including potentially ""bad controls"". We therefore chose to take a dbeta from the model in which the controls had the least obvious effect.",0.003805068,0.045453229
621,124,m,tyrka2010,tyrka,2010,Childhood Maltreatment and Telomere Shortening: Preliminary Support for an Effect of Early Stress on Cellular Aging,homo sapiens,Childhood maltreatment (Childhood Trauma Questionnaire),psychosocial,traumatic experience,more adversity,0-17 years,3102.5,4927.5,child,44712.5,unreported,Thirty-one adults with no current or past major Axis I psychiatric disorder.,0,NA,0,NA,9818.5,adult,0,childadult,22,9,both,31,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Maltreatment.NoMaltreatment,LTL T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.707869984,0.7,1.02,NA,NA,0.24,0.52,10,21,NA,NA,NA,NA,NA,,-0.314150931,0.027078609
622,126,ss124,tyrka2010,tyrka,2010,Childhood Maltreatment and Telomere Shortening: Preliminary Support for an Effect of Early Stress on Cellular Aging,homo sapiens,Emotional neglect (Childhood Trauma Questionnaire),psychosocial,traumatic experience,more adversity,0-17 years,3102.5,4927.5,child,44712.5,unreported,Thirty-one adults with no current or past major Axis I psychiatric disorder.,0,NA,0,NA,9818.5,adult,0,childadult,unreported,unreported,both,31,leukocytes,wbcs,qpcr,0,0,NA,1,positive,EmotionalNeglect.NoMaltreatment,LTL T/S ratio,negative,0,ttest,1,NA,NA,2.2,25.6,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.398749688,0.02357596
623,127,ss124,tyrka2010,tyrka,2010,Childhood Maltreatment and Telomere Shortening: Preliminary Support for an Effect of Early Stress on Cellular Aging,homo sapiens,Physical neglect (Childhood Trauma Questionnaire),psychosocial,traumatic experience,more adversity,0-17 years,3102.5,4927.5,child,44712.5,unreported,Thirty-one adults with no current or past major Axis I psychiatric disorder.,0,NA,0,NA,9818.5,adult,0,childadult,unreported,unreported,both,31,leukocytes,wbcs,qpcr,0,0,NA,1,positive,PhysicalNeglect.NoMaltreatment,LTL T/S ratio,negative,0,ttest,1,NA,NA,3.5,26.9,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,,0.559373852,0.015736921
624,128,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.Adversity&NoDisorder),psychosocial,other negative,more adversity,0-18 years,3285,4927.5,child,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,10913.5,adult,0,childadult,103,76,both,179,leukocytes,wbcs,qpcr,0,0,NA,0,negative,NoAdversity&NoDisorder.Adversity&NoDisorder,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.185744144,6432.9,7181,NA,NA,3372.7,4362.8,66,113,NA,NA,NA,NA,NA,,-0.089255798,0.005528822
625,129,m,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.ParentalLoss),psychosocial,other negative,more adversity,0-18,3285,4927.5,child,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,0,childadult,unreported,unreported,both,189,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.ParentalLoss,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.166394605,6482.9,7181,NA,NA,3932.3,4362.8,76,113,NA,NA,NA,NA,NA,,-0.081317272,0.005249036
626,130,m,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.Maltreatment),psychosocial,other negative,more adversity,0-17,3102.5,4927.5,child,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,0,childadult,unreported,unreported,both,214,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.Maltreatment,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.279733424,6034.1,7181,NA,NA,3784,4362.8,101,113,NA,NA,NA,NA,NA,,-0.138304601,0.004516946
627,131,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.PastSubstanceAbuse),psychosocial,other negative,more adversity,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,unreported,unreported,both,168,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.PastSubstanceAbuse,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.066665217,6893.3,7181,NA,NA,4216,4362.8,55,113,NA,NA,NA,NA,NA,,-0.031267862,0.005976321
628,132,m,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Socioeconomic Adversity,socioeconomic,composite measure,lower,unreported,unreported,4927.5,child,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,0,childadult,177,113,both,290,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood Socioeconomic Adversity,LTL base pairs log transformed,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.07,NA,NA,NA,,-0.07,0.003426381
629,133,m,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Education,socioeconomic,education,higher,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,177,113,both,290,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Education,LTL base pairs log transformed,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,NA,NA,NA,,0.05,0.003442928
630,134,m,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.Adversity&Disorder),psychiatric,other,none,0-18 years,3285,4927.5,child,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11552.25,adult,0,childadult,113,72,both,185,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.Adversity&Disorder,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.359662893,5642.7,7181,NA,NA,4138.2,4362.8,72,113,NA,NA,NA,NA,NA,,-0.172723926,0.005115342
631,135,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.NoAdversity&Disorder),psychiatric,other,none,Mean = 29.6 years,10804,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,10804,adult,1,adultadult,87,65,both,152,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.NoAdversity&Disorder,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.357161995,5642.7,7181,NA,NA,4138.2,4362.8,39,113,NA,NA,NA,NA,NA,,-0.154124864,0.006311625
632,136,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.LifetimeMDD),psychiatric,other,none,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,unreported,unreported,both,161,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.LifetimeMDD,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.554864963,4933,7181,NA,NA,3189.2,4362.8,48,113,NA,NA,NA,NA,NA,,-0.24601642,0.005516344
633,137,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.LifetimeDepressive),psychiatric,other,none,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,unreported,unreported,both,172,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.LifetimeDepressive,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.567691835,4855.5,7181,NA,NA,3525.5,4362.8,59,113,NA,NA,NA,NA,NA,,-0.260210634,0.005082839
634,138,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.LifetimePTSD),psychiatric,other,none,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,unreported,unreported,both,125,leukocytes,wbcs,qpcr,0,0,NA,0,negative,NoAdversity&NoDisorder.LifetimePTSD,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.499593176,5064.7,7181,NA,NA,2616.6,4362.8,12,113,NA,NA,NA,NA,NA,,-0.145607245,0.007726182
635,139,sg24,tyrka2016,tyrka,2016,Alterations of Mitochondrial DNA Copy Number and Telomere Length with Early Adversity and Psychopathology,homo sapiens,Childhood Trauma Questionnaire & Structured Clinical Interview for DSM-IV (NoAdversity&NoDisorder.LifetimeAnxiety),psychiatric,other,none,Mean = 31.325 years,11433.625,4927.5,adult,44712.5,unreported,"Two hundred ninety participants, 177 women and 113 men, aged 18 to 61 (31.0 6 10.7) years were recruited using separate local, newspaper, and internet advertisements directed toward healthy adults and individuals with depression, childhood parental loss, or a history of early life stress. Participants were white (n = 241), black (n = 26), Asian (n = 9), Hispanic (n = 4), and other (n = 10). Subjects from our prior study of adversity and telomere length (70) were not included.",0,NA,0,NA,11433.625,adult,1,adultadult,unreported,unreported,both,141,leukocytes,wbcs,qpcr,0,0,NA,1,negative,NoAdversity&NoDisorder.LifetimeAnxiety,LTL base pairs,negative,0,meanssd,1,NA,NA,NA,NA,-0.576141526,4802.8,7181,NA,NA,2960.1,4362.8,28,113,NA,NA,NA,NA,NA,,-0.224000909,0.006444035
636,1,m,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control (perception that one is being controlled by others),psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived network social control (perception that one is being controlled by others),PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.21,NA,NA,NA,,-0.21,0.006573704
637,2,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control from children,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived network social control from children,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.17,NA,NA,NA,,-0.17,0.006784426
638,3,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control from friends,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Perceived network social control from friends,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,,-0.13,0.006953134
639,4,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control from siblings,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Perceived network social control from siblings,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,,-0.13,0.006953134
640,5,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control from medical doctors,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,0,negative,Perceived network social control from medical doctors,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.13,NA,NA,NA,,-0.13,0.006953134
641,6,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control in health behaviours,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived network social control in health behaviours,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.19,NA,NA,NA,,-0.19,0.006684196
642,7,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control in health care utilization,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived network social control in health care utilization,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.2,NA,NA,NA,,-0.2,0.006630216
643,8,ss1,uchino2015,uchino,2015,A cross-sectional analysis of the association between perceived network social control and telomere length,homo sapiens,Perceived network social control in lifestyle,psychosocial,other negative,more adversity,48-77 years,21973,4927.5,adult,44712.5,unreported,"One-hundred and 40 relatively healthy participants recruited from the community using flyers and advertisement in local papers. Most participants were
White (93%), with 4% Hispanic/Latino, 2% Asian, and 1% Native American. The median education was college graduation, with a median yearly income of $40,000 or more. Most participants were either married (66.2%) or divorced (20.1%) but some were single/never wed (7.9%). A small number of participants were widowed or separated (5.8%).",0,NA,0,NA,21973,adult,1,adultadult,55,85,both,140,pbmcs,wbcs,qpcr,0,0,NA,1,negative,Perceived network social control in lifestyle,PBMC T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.16,NA,NA,NA,,-0.16,0.006830614
644,427,m,valdes2005,valdes,2005,"Obesity, cigarette smoking, and telomere length in women",homo sapiens,Smoking status,smoking,none,none,Mean age = 47.77,17436.05,"4,745",adult,44712.5,unreported,Participants were female twins (45 monozygotic and 516 dizygotic pairs) from the TwinsUK cohort,1,zierer2016,0,NA,17436.05,adult,1,adultadult,1122,0,female,1122,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Smokers.Non-smokers,Leukocyte TRF,negative,0,correlationcoefficient,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.031,NA,NA,NA,NA,,-0.031,0.000890347
645,428,ss427,valdes2005,valdes,2005,"Obesity, cigarette smoking, and telomere length in women",homo sapiens,Cigarette pack-years ,smoking,none,none,Mean age = 47.77,17436.05,"4,745",adult,44712.5,NA,Participants were female twins (45 monozygotic and 516 dizygotic pairs) from the TwinsUK cohort,1,zierer2016,0,NA,17436.05,adult,1,adultadult,1122,0,female,1122,leukocytes,wbcs,southernblot,0,0,NA,1,negative,Cigarettes pack-years,Leukocyte TRF,negative,0,correlationcoefficient,0,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.214,NA,NA,NA,NA,,-0.214,0.000812226
646,429,sg56,vasan2008,vasan,2008,Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: The Framingham heart study,homo sapiens,Hypertensive status (males),disease,cardiovascular,none,Mean age = 60.5,22082.5,"5,110",adult,44712.5,unreported,"1203 Framingham Study participants (mean age, 59 years; 51% women)",0,NA,0,NA,22082.5,adult,1,adultadult,0,577,male,577,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Hypertensive.Nonhpyertensive (males),LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.269526752,6.8,6.95,NA,NA,0.54,0.57,263,314,NA,NA,NA,NA,NA,,-0.133042612,0.001675196
647,430,sg56,vasan2008,vasan,2008,Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: The Framingham heart study,homo sapiens,Hypertensive status (females),disease,cardiovascular,none,Mean age = 59,21535,"4,745",adult,44712.5,unreported,"1203 Framingham Study participants (mean age, 59 years; 51% women)",0,NA,0,NA,21535,adult,1,adultadult,622,0,female,622,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Hypertensive.Nonhpyertensive (females),LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.187047032,6.97,7.08,NA,NA,0.57,0.6,251,371,NA,NA,NA,NA,NA,,-0.091382554,0.001583524
648,431,m,vasan2008,vasan,2008,Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: The Framingham heart study,homo sapiens,Hypertensive status,disease,cardiovascular,none,Mean age = 59.5,21717.5,4927.5,adult,44712.5,unreported,"1203 Framingham Study participants (mean age, 59 years; 51% women)",0,NA,0,NA,21717.5,adult,1,adultadult,623,580,both,1199,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Hypertensive.Nonhpyertensive ,LTL kb,negative,0,meanssd,1,NA,NA,NA,NA,-0.23981241,6.883015564,7.020408759,NA,NA,0.554649805,0.586248175,514,685,NA,NA,NA,NA,NA,,-0.117853402,0.000811698
649,664,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Education,socioeconomic,education,higher,41.8 ± 13.1 years,15257,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Education,Leucocyte T/S ratio converted to bp,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.021393841,4,3.3,617,,0.071393841,0.000337251
650,665,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Physical activity,physicalactivity,more activity,none,41.8 ± 13.1 years,15257,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Physical activity,Leucocyte T/S ratio converted to bp,positive,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0,0,3,617,,0.05,0.000339014
651,666,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Childhood adverse life events,psychosocial,traumatic experience,more adversity,Childhood,unreported,4927.5,child,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,0,childadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood adverse life events,Leucocyte T/S ratio converted to bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.004,NA,NA,NA,,0.054,0.000338731
652,667,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Childhood trauma,psychosocial,traumatic experience,more adversity,Childhood,unreported,4927.5,child,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,0,childadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Childhood trauma (CTI),Leucocyte T/S ratio converted to bp,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.023,NA,NA,NA,,-0.023,0.000340355
653,668,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Stressful life events past year,psychosocial,traumatic experience,more adversity,Adulthood,14892,4927.5,adult,44712.5,182.5,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Stressful life events past year,Leucocyte T/S ratio converted to bp,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.039,NA,NA,NA,,-0.039,0.00033968
654,669,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Stressful life events 1-5 years ago,psychosocial,traumatic experience,more adversity,Adulthood,14344.5,4927.5,adult,44712.5,730,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Stressful life events 1-5 years ago,Leucocyte T/S ratio converted to bp,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.042,NA,NA,NA,,-0.042,0.000339515
655,670,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Stressful life events >5 years ago,psychosocial,traumatic experience,more adversity,Adulthood,6716,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Stressful life events >6 years ago,Leucocyte T/S ratio converted to bp,positive,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.1,NA,NA,NA,,0.15,0.000325556
656,671,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Number of chronic diseases (physical),disease,other,none,Adulthood,unreported,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,986,both,2936,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Number of chronic diseases (physical),Leucocyte T/S ratio converted to bp,negative,1,ubeta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.107358185,-73.6,0.9,617,,-0.107358185,0.000332907
657,661,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Smoking current vs. never,smoking,none,none,41.8 ± 13.1 years,15257,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,12,both,1962,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smoking current vs. never,Leucocyte T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.19465154,NA,NA,NA,NA,NA,NA,1136,826,NA,NA,-120.1,NA,617,,-0.095662494,0.000500653
658,662,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Smoking former vs. never,smoking,none,none,41.8 ± 13.1 years,15257,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,-150,both,1800,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smoking former vs. never,Leucocyte T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.211345219,NA,NA,NA,NA,NA,NA,974,826,NA,NA,-130.4,NA,617,,-0.104735584,0.000543736
659,663,m,verhoeven2015,verhoeven,2015,The association of early and recent psychosocial life stress with leukocyte telomere length,homo sapiens,Alcohol heavy drinker vs. moderate,alcohol,more alcohol,none,41.8 ± 13.1 years,15257,4927.5,adult,44712.5,unreported,Netherlands Study of Depression and Anxiety (NESDA),0,NA,0,NA,15257,adult,1,adultadult,1950,486,both,2436,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Alcohol heavy drinker vs. moderate,Leucocyte T/S ratio converted to bp,negative,1,dbeta,1,NA,NA,NA,NA,-0.19821718,NA,NA,NA,NA,NA,NA,373,2063,NA,NA,-122.3,NA,617,,-0.07119746,0.000406525
660,257,m,vo2011,vo,2011,Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls,homo sapiens,Acute phase hip fracture vs healthy age-matched controls,disease,other,none,Mean age = 82.85,30240.25,4927.5,adult,44712.5,unreported,"Thirty-five aged patients with hip fracture (mean age 83.4±5.7, range 75 to 97) and 28 healthy aged controls (mean age 82.3±6.0, range 75 to 103) recruited at the the University Hospital of Mont-Godinne, UCLouvain, Belgium.",0,NA,0,NA,30240.25,adult,1,adultadult,unreported,unreported,both,63,pbmcs,wbcs,qpcr,0,0,NA,1,negative,AcutePhaseHipFracture.Controls,PBMC T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.895883641,100.86,365.02,NA,NA,150.39,409.81,35,28,NA,NA,NA,NA,NA,,-0.406690496,0.011234869
661,258,ss257,vo2011,vo,2011,Differentially abundant transcripts in PBMC of hospitalized geriatric patients with hip fracture compared to healthy aged controls,homo sapiens,Convalescence after hip fracture vs health age-matched controls,disease,other,none,Mean age = 82.85,30240.25,4927.5,adult,44712.5,unreported,"Thirty-five aged patients with hip fracture (mean age 83.4±5.7, range 75 to 97) and 28 healthy aged controls (mean age 82.3±6.0, range 75 to 103) recruited at the the University Hospital of Mont-Godinne, UCLouvain, Belgium.",0,NA,0,NA,30240.25,adult,1,adultadult,unreported,unreported,both,63,pbmcs,wbcs,qpcr,0,0,NA,0,negative,ConvalescenceAfterHipFracture.Controls,PBMC T/S ratio,negative,0,meanssd,1,NA,NA,NA,NA,-0.965672779,86.9,365.02,NA,NA,124.3,409.81,35,28,NA,NA,NA,NA,NA,,-0.432618705,0.010656622
662,259,m,wang2011,wang,2011,Association of shorter mean telomere length with large artery stiffness in patients with coronary heart disease,homo sapiens,Coronary heart disease status,disease,cardiovascular,none,40–73 years,20805,"5,110",adult,44712.5,unreported,275 unrelated Chinese Han subjects (163 patients with coronary heart disease and 112 healthy controls) were recruited from Qingdao Municipal Hospital between October 2007 and October 2009.,0,NA,0,NA,20805,adult,1,adultadult,0,275,male,275,leukocytes,wbcs,qpcr,0,0,NA,1,negative,CHDPatients.Controls,LTL T/S ratio,negative,1,meanssd,1,NA,NA,NA,NA,-1.185963572,0.79,1.08,NA,NA,0.26,0.22,163,112,NA,NA,NA,NA,NA,,-0.503459616,0.002033959
663,260,m,wang2011,wang,2011,Association of shorter mean telomere length with large artery stiffness in patients with coronary heart disease,homo sapiens,Smoking,smoking,none,none,40–73 years,20805,"5,110",adult,44712.5,unreported,275 unrelated Chinese Han subjects (163 patients with coronary heart disease and 112 healthy controls) were recruited from Qingdao Municipal Hospital between October 2007 and October 2009.,0,NA,0,NA,20805,adult,1,adultadult,0,275,male,275,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Smokers.Non-smokers,LTL T/S ratio,negative,1,meanssd,1,NA,NA,NA,NA,-0.706627126,0.83,1.04,NA,NA,0.31,0.29,97,178,NA,NA,NA,NA,NA,,-0.319897448,0.002940889
664,524,m,watfa2011,watfa,2011,Study of telomere length and different markers of oxidative stress in patients with Parkinson's disease,homo sapiens,Parkinson's disease,disease,parkinsons,none,Average 78.1 years,28506.5,4927.5,adult,44712.5,Unreported,Parkinson's disease patients and healthy controls,0,NA,0,NA,28506.5,adult,1,adultadult,20,15,both ,35,leukocytes,wbcs,southernblot,0,0,NA,0,negative,Parkinson's disease vs. control,Mean TRF,negative,0,meanssd,1,NA,NA,NA,NA,-0.54049384,6.03,6.45,NA,NA,0.81,0.73,20,15,NA,NA,NA,NA,NA,,-0.258391692,0.025615447
665,319,m,wei2015,wei,2015,hTERT genetic variation in depression,homo sapiens,"Depression (MDD, mixed anxiety depression or dysthymia in DSM-IV)",psychiatric,depression and anxiety,depression and anxiety,Mean = 43.5,15877.5,4927.5,adult,44712.5,unreported,The PART cohort - Randomly-selected Swedish nationals aged 20–64 years,0,NA,0,NA,15877.5,adult,1,adultadult,431,231,both,662,saliva,buccal,qpcr,0,0,NA,1,negative,Depressed.Controls,Saliva telomere length,negative,0,meansse,1,NA,NA,NA,NA,-0.343368594,0.71,0.84,0.02,0.02,0.30724583,0.412795349,236,426,NA,NA,NA,NA,NA,,-0.162281167,0.001434226
666,469,m,wikgren2012,wikgren,2012,Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State,homo sapiens,Major depression (patients vs controls),psychiatric,depression and anxiety,depression,Mean age = 59.1 years (mean duration of illness = 27.9),11388,4927.5,adult,44712.5,10183.5,"91 subjects with recurrent major depressive disorder, within psychiatric care in the region of Umeå in northern Sweden between 1998 and 2001 who met the DSM-IV diagnostic criteria for major depressive disorder, and 451 control subjects between 25 and 81 years old, recruited from the Betula study.",0,NA,0,NA,21571.5,adult,1,adultadult,279,263,both,542,leukocytes,wbcs,qpcr,0,0,NA,1,negative,DepressivePatients.Controls,LTL bp,negative,1,meansse,1,NA,NA,NA,NA,-0.400242632,5261,5538,35,35,333.8787205,743.2866204,91,451,NA,NA,NA,NA,NA,"This paper also reports ""attrition"" data, which we haven't used as the small print says, ""on the basis of cross-sectional data,"" and the methods section doesn't explain how ""attrition"" was calculated. ",-0.147954026,0.001768389
667,470,sg469,wikgren2012,wikgren,2012,Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State,homo sapiens,Major depression in men (patients vs controls),psychiatric,depression and anxiety,depression,Mean age = 59.1 years (mean duration of illness = 27.9),11388,"5,110",adult,44712.5,10183.5,"91 subjects with recurrent major depressive disorder, within psychiatric care in the region of Umeå in northern Sweden between 1998 and 2001 who met the DSM-IV diagnostic criteria for major depressive disorder, and 451 control subjects between 25 and 81 years old, recruited from the Betula study.",0,NA,0,NA,21571.5,adult,1,adultadult,0,260,male,260,leukocytes,wbcs,qpcr,0,0,NA,1,negative,DepressiveMen.ControlMen,LTL bp,negative,1,meansse,1,NA,NA,NA,NA,-0.385259431,5199,5493,127,51,762,763.2981069,36,224,NA,NA,NA,NA,NA,"This paper also reports ""attrition"" data, which we haven't used as the small print says, ""on the basis of cross-sectional data,"" and the methods section doesn't explain how ""attrition"" was calculated. ",-0.131899792,0.003727828
668,471,sg469,wikgren2012,wikgren,2012,Short Telomeres in Depression and the General Population Are Associated with a Hypocortisolemic State,homo sapiens,Major depression in women (patients vs controls),psychiatric,depression and anxiety,depression,Mean age = 59.1 years (mean duration of illness = 27.9),11388,"4,745",adult,44712.5,10183.5,"91 subjects with recurrent major depressive disorder, within psychiatric care in the region of Umeå in northern Sweden between 1998 and 2001 who met the DSM-IV diagnostic criteria for major depressive disorder, and 451 control subjects between 25 and 81 years old, recruited from the Betula study.",0,NA,0,NA,21571.5,adult,1,adultadult,282,0,female,282,leukocytes,wbcs,qpcr,0,0,NA,1,negative,DepressiveWomen.ControlWomen,LTL bp,negative,1,meansse,1,NA,NA,NA,NA,-0.364697336,5326,5584,95,47,704.5388563,708.1264011,55,227,NA,NA,NA,NA,NA,"This paper also reports ""attrition"" data, which we haven't used as the small print says, ""on the basis of cross-sectional data,"" and the methods section doesn't explain how ""attrition"" was calculated. ",-0.143017819,0.003414627
669,579,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms prenatal,psychiatric,other,none,embryonic,embryonic,4927.5,embryonic,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,0,embryonicchild,unreported,unreported,both,203,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms prenatal,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.124147864,7879.79,7762.35,129.32,76.38,1042.611172,897.2618387,65,138,NA,NA,NA,NA,NA,,0.057824535,0.004917445
670,580,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 4-6 weeks,psychiatric,other,none,4-6 weeks,35,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,203,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 4-6 weeks,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.038500616,7828.67,7792.08,137.92,76,893.8237571,964.3318931,42,161,NA,NA,NA,NA,NA,,0.01559396,0.004948088
671,581,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 6 months,psychiatric,other,none,6 months,180,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,182,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 6 months,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.323401714,8082.31,7770.15,162.93,79.62,950.0369922,968.6191053,34,148,NA,NA,NA,NA,NA,,0.125059943,0.005353396
672,582,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 12 months,psychiatric,other,none,12 months,4380,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,191,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 12 months,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.013607945,7828.05,7814.96,165.23,75.77,792.4152426,982.0914454,23,168,NA,NA,NA,NA,NA,,0.004428672,0.005262951
673,583,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 3 years,psychiatric,other,none,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,192,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 3 years,T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.261582757,7571.43,7794.28,137.08,68.15,738.1983918,870.0809546,29,163,NA,NA,NA,NA,NA,,-0.093261786,0.005144922
674,584,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 4 years,psychiatric,other,none,4 years,1460,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,193,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 4 years,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.145676451,7926.05,7785.83,192.77,73.89,1073.297936,940.4661611,31,162,NA,NA,NA,NA,NA,,0.053413372,0.005178657
675,585,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,Maternal depressive symptoms 5 years,psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,195,wholeblood,wbcs,qpcr,0,0,NA,0,negative,Maternal depressive symptoms 5 years,T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.125724883,7890.17,7777.86,181.25,66.35,1117.300038,831.3631171,38,157,NA,NA,NA,NA,NA,NB. There was a typing error in table 1 for this association.,0.049738237,0.005129167
676,586,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (attention, 3 yrs)",psychiatric,other,none,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,200,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (attention, 3 yrs)",T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.105448734,7895.25,7795.62,382.1,67.8,1080.742004,939.464358,8,192,NA,NA,NA,NA,NA,,0.020659237,0.005020837
677,587,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (anxiety, 3 yrs)",psychiatric,depression and anxiety,anxiety,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,200,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (anxiety, 3 yrs)",T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.00429166,7803.21,7799.14,147.18,73.44,721.0318007,974.2916984,24,176,NA,NA,NA,NA,NA,,0.001394623,0.005025106
678,588,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (affective, 3 yrs)",psychiatric,other,none,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,200,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (affective, 3 yrs)",T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.319147627,8078.77,7780.14,213.19,69.14,768.6674764,945.4752801,13,187,NA,NA,NA,NA,NA,,0.07843575,0.004963485
679,589,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (developmental, 3yrs)",psychiatric,other,none,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,200,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (developmental, 3yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.095098682,7726.13,7816.06,131.3,76.23,787.8,976.2203212,36,164,NA,NA,NA,NA,NA,,-0.03651136,0.005011737
680,590,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (oppositional, 3yrs)",psychiatric,other,none,3 years,1095,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,200,wholeblood,wbcs,qpcr,0,0,NA,1,negative,"Child behaviour issue (oppositional, 3yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.89601545,6981.04,7816.29,336.02,66.83,672.04,935.62,4,196,NA,NA,NA,NA,NA,,-0.124466698,0.004870634
681,591,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (attention, 4 yrs)",psychiatric,other,none,4 years,1460,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (attention, 4 yrs)",T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.289077714,8080.13,7808.19,184.08,68.85,487.0299013,951.5259311,7,191,NA,NA,NA,NA,NA,,0.053308585,0.005047332
682,592,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (anxiety, 4 yrs)",psychiatric,depression and anxiety,anxiety,4 years,1460,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (anxiety, 4 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.285644266,7552.01,7823.48,164.4,69.62,434.9615155,962.1675428,7,191,NA,NA,NA,NA,NA,,-0.052677193,0.00504801
683,593,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (affective, 4 yrs)",psychiatric,other,none,4 years,1460,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (affective, 4 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.219715993,7612.55,7821.24,177.97,69.54,470.8643608,961.0619208,7,191,NA,NA,NA,NA,NA,,-0.040541982,0.005059469
684,594,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (developmental, 4 yrs)",psychiatric,other,none,4 years,1460,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (developmental, 4 yrs)",T/S ratio converted to bp,positive,0,meansse,1,NA,NA,NA,NA,0.052843496,7860.86,7810.59,207.22,70.64,717.8311367,963.4011551,12,186,NA,NA,NA,NA,NA,,0.012607789,0.005074528
685,595,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (oppositional, 5 yrs)",psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,1,negative,"Child behaviour issue (oppositional, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.442511635,7401.84,7822.3,155.2,68.69,310.4,956.7409908,4,194,NA,NA,NA,NA,NA,,-0.062137008,0.00503702
686,596,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (attention, 5 yrs)",psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (attention, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.11564854,7699.68,7809.27,283.86,68.8,695.3121584,953.3207645,6,192,NA,NA,NA,NA,NA,,-0.019820558,0.005072155
687,597,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (anxiety, 5 yrs)",psychiatric,depression and anxiety,anxiety,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,1,negative,"Child behaviour issue (anxiety, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.358270813,7479.73,7818.05,97.07,69.32,256.8230798,958.0214603,7,191,NA,NA,NA,NA,NA,,-0.066018167,0.005031991
688,598,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (affective, 5 yrs)",psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,198,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (affective, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.048074718,7762.69,7808.15,211.99,69.58,635.97,956.5668506,9,189,NA,NA,NA,NA,NA,,-0.010013409,0.005075124
689,599,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (developmental, 5 yrs)",psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,193,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (developmental, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.27031417,7564.53,7819.44,225.3,69.3,503.7861153,950.1937276,5,188,NA,NA,NA,NA,NA,,-0.042901788,0.005189178
690,600,m,wojcicki2015,wojcicki,2015,Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children,homo sapiens,"Child behaviour issue (oppositional, 5 yrs)",psychiatric,other,none,4.5 years,1642.5,4927.5,child,44712.5,unreported,Latino preschool children from San Francisco,0,NA,0,NA,1642.5,child,1,childchild,unreported,unreported,both,202,wholeblood,wbcs,qpcr,0,0,NA,0,negative,"Child behaviour issue (oppositional, 5 yrs)",T/S ratio converted to bp,negative,0,meansse,1,NA,NA,NA,NA,-0.319797572,7519.63,7820.43,198.91,68.76,629.0086494,952.7665082,10,192,NA,NA,NA,NA,NA,,-0.069204119,0.004927585
691,357,m,wolkowitz2011,wolkowitz,2011,"Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings",homo sapiens,Household income,socioeconomic,income,higher,Mean age = 36.7,13395.5,4927.5,adult,44712.5,unreported,"Eighteen subjects with MDD & 18 individually-matched healthy controls (matched by sex, ethnicity and age ±3 years).",1,chen2014,0,NA,13395.5,adult,1,adultadult,23,13,both,36,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Household income,LTL bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.13,NA,NA,NA,NA,,0.13,0.027613875
692,358,m,wolkowitz2011,wolkowitz,2011,"Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings",homo sapiens,Physical activity levels per month - measured by the Yale Physical Activity Survey (YPAS),physicalactivity,more activity,none,Mean age = 36.7,13395.5,4927.5,adult,44712.5,unreported,"Eighteen subjects with MDD & 18 individually-matched healthy controls (matched by sex, ethnicity and age ±3 years).",1,chen2014,0,NA,13395.5,adult,1,adultadult,23,13,both,36,leukocytes,wbcs,qpcr,0,0,NA,0,positive,Physical activity,LTL bp,positive,0,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.19,NA,NA,NA,NA,,0.19,0.026545806
693,360,m,wolkowitz2011,wolkowitz,2011,"Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings",homo sapiens,Current depressive status,psychiatric,depression and anxiety,depression,Mean age = 36.7,13395.5,4927.5,adult,44712.5,3805.125,"Eighteen subjects with MDD & 18 individually-matched healthy controls (matched by sex, ethnicity and age ±3 years).",1,chen2014,0,NA,13395.5,adult,1,adultadult,23,12,both,35,leukocytes,wbcs,qpcr,0,0,NA,0,negative,CurrentDepressive.Controls,LTL bp,negative,0,meanssd,1,NA,NA,NA,NA,-0.110260916,5101,5141,NA,NA,425,282,18,17,NA,NA,NA,NA,NA,,-0.055024463,0.029233935
694,187,m,wong2014a,wong,2014a,Cumulative PM25 exposure and telomere length in workers exposed to welding fumes,homo sapiens,Ever having smoked,smoking,none,none,Mean age = 39.3 (at baseline),14344.5,"5,110",adult,44712.5,unreported,"48 male subjects of the boilermakers’ blood subcohort. The subjects were 87.5% self-identified whites, whereas the remaining 12.5% of subjects were identified as African-American, Hispanic, and Asian.",0,NA,0,NA,14344.5,adult,1,adultadult,0,48,male,48,leukocytes,wbcs,qpcr,0,0,NA,0,negative,EverSmokers.NeverSmokers,Natural-scaled LTL T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.243746455,0.66,0.62,NA,NA,0.16,0.18,38,10,NA,NA,NA,NA,NA,,0.098507982,0.020865671
695,189,m,wong2014a,wong,2014a,Cumulative PM25 exposure and telomere length in workers exposed to welding fumes,homo sapiens,Cumulative PM2.5 exposure (career),environmentalhazard,none,none,Mean age = 39.3 (at baseline),10840.5,"5,110",adult,44712.5,3504,"48 male subjects of the boilermakers’ blood subcohort. The subjects were 87.5% self-identified whites, whereas the remaining 12.5% of subjects were identified as African-American, Hispanic, and Asian.",0,NA,0,NA,14344.5,adult,1,adultadult,0,48,male,48,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cumulative PM2.5 exposure (over lifetime career),Natural-scaled LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.021,NA,NA,NA,,-0.021,0.021257834
696,190,ss189,wong2014a,wong,2014a,Cumulative PM25 exposure and telomere length in workers exposed to welding fumes,homo sapiens,Cumulative PM2.5 exposure (1 year before blood draw),environmentalhazard,none,none,Mean age = 39.3 (at baseline),10840.5,"5,110",adult,44712.5,3504,"48 male subjects of the boilermakers’ blood subcohort. The subjects were 87.5% self-identified whites, whereas the remaining 12.5% of subjects were identified as African-American, Hispanic, and Asian.",0,NA,0,NA,14344.5,adult,1,adultadult,0,48,male,48,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Cumulative PM2.5 exposure (over 1 year before blood draw),Natural-scaled LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.022,NA,NA,NA,,-0.022,0.021256005
697,191,ss189,wong2014a,wong,2014a,Cumulative PM25 exposure and telomere length in workers exposed to welding fumes,homo sapiens,Cumulative PM2.5 exposure (1 month before blood draw),environmentalhazard,none,none,Mean age = 39.3 (at baseline),10840.5,"5,110",adult,44712.5,3504,"48 male subjects of the boilermakers’ blood subcohort. The subjects were 87.5% self-identified whites, whereas the remaining 12.5% of subjects were identified as African-American, Hispanic, and Asian.",0,NA,0,NA,14344.5,adult,1,adultadult,0,48,male,48,leukocytes,wbcs,qpcr,0,0,NA,1,negative,Cumulative PM2.5 exposure (over 1 month before blood draw),Natural-scaled LTL T/S ratio,negative,1,beta,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.04,NA,NA,NA,,-0.04,0.021208565
698,188,ss187,wong2014a,wong,2014a,Cumulative PM25 exposure and telomere length in workers exposed to welding fumes,homo sapiens,Being a current smoker,smoking,none,none,Mean age = 39.3 (at baseline),14344.5,"5,110",adult,44712.5,unreported,"48 male subjects of the boilermakers’ blood subcohort. The subjects were 87.5% self-identified whites, whereas the remaining 12.5% of subjects were identified as African-American, Hispanic, and Asian.",0,NA,0,NA,14344.5,adult,1,adultadult,0,48,male,47,leukocytes,wbcs,qpcr,0,0,NA,0,negative,CurrentSmokers.NonSmokers,Natural-scaled LTL T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.125,0.65,0.63,NA,NA,0.16,0.16,22,25,NA,NA,NA,NA,NA,,0.062251578,0.021570967
699,693,m,wong2014b,wong,2014b,The relationship between inflammatory biomarkers and telomere length in an occupational prospective cohort study,homo sapiens,Smoking: smoker vs. non-smoker,smoking,none,none,41.5 ± 13 years,15147.5,"5,110",adult,44712.5,unreported,Harvard boilermakers longitudinal study,1,wong2014a,1,NA,15147.5,adult,1,adultadult,0,83,male,83,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking: smoker vs. non-smoker,Leucocyte T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0.340208529,0.66,0.6,NA,NA,0.17,0.18,31,52,NA,NA,NA,NA,NA,,0.162385341,0.011560455
700,694,ss693,wong2014b,wong,2014b,The relationship between inflammatory biomarkers and telomere length in an occupational prospective cohort study,homo sapiens,Smoking: ever vs. never smoked,smoking,none,none,41.5 ± 13 years,15147.5,"5,110",adult,44712.5,unreported,Harvard boilermakers longitudinal study,1,wong2014a,1,NA,15147.5,adult,1,adultadult,0,64,male,64,leukocytes,wbcs,qpcr,0,0,NA,0,negative,Smoking: ever vs. never smoked,Leucocyte T/S ratio,positive,0,meanssd,1,NA,NA,NA,NA,0,0.63,0.63,NA,NA,0.17,0.22,17,47,NA,NA,NA,NA,NA,,0,0.015873016
701,413,m,woo2008,woo,2008,No Association Between Physical Activity and Telomere Length in an Elderly Chinese Population 65 Years and Older,homo sapiens,Low-moderate physical activity versus very low (2nd quartile vs 1st) in elderly people - measured using PASE (Physical Activity Scale for the Elderly),physicalactivity,more activity,none,Mean age = 72.37,26415.05,4927.5,adult,44712.5,unreported,"Four thousand men and women 65 years and older living in the community participated in a health survey between 2001 and 2003, in China.",0,NA,0,NA,26415.05,adult,1,adultadult,1030,976,both,1007,leukocytes,wbcs,southernblot,0,0,NA,0,positive,VeryLowPhysicalActivity.Low-ModeratePhysicalActivity,LTL TRF (kbp),positive,0,meansse,1,NA,NA,NA,NA,-0.074274288,8.95,9.1,0.09,0.09,2.026499445,2.01246118,507,500,NA,NA,NA,NA,NA,,-0.037110666,0.0009913
702,414,m,woo2008,woo,2008,No Association Between Physical Activity and Telomere Length in an Elderly Chinese Population 65 Years and Older,homo sapiens,Moderate physical activity versus very low (3rd quartile vs 1st) in elderly people - measured using PASE (Physical Activity Scale for the Elderly),physicalactivity,more activity,none,Mean age = 72.37,26415.05,4927.5,adult,44712.5,unreported,"Four thousand men and women 65 years and older living in the community participated in a health survey between 2001 and 2003, in China.",0,NA,0,NA,26415.05,adult,1,adultadult,1030,976,both,1005,leukocytes,wbcs,southernblot,0,0,NA,0,positive,VeryLowPhysicalActivity.ModeratePhysicalActivity,LTL TRF (kbp),positive,0,meansse,1,NA,NA,NA,NA,-0.104085757,8.95,9.16,0.09,0.09,2.026499445,2.008432224,507,498,NA,NA,NA,NA,NA,,-0.051970465,0.000990643
703,415,m,woo2008,woo,2008,No Association Between Physical Activity and Telomere Length in an Elderly Chinese Population 65 Years and Older,homo sapiens,High physical activity versus very low (4th quartile vs 1st) in elderly people - measured using PASE (Physical Activity Scale for the Elderly),physicalactivity,more activity,none,Mean age = 72.37,26415.05,4927.5,adult,44712.5,unreported,"Four thousand men and women 65 years and older living in the community participated in a health survey between 2001 and 2003, in China.",0,NA,0,NA,26415.05,adult,1,adultadult,1030,976,both,1008,leukocytes,wbcs,southernblot,0,0,NA,0,positive,VeryLowPhysicalActivity.HighPhysicalActivity,LTL TRF (kbp),positive,0,meansse,1,NA,NA,NA,NA,-0.098983888,8.95,9.15,0.09,0.09,2.026499445,2.014472636,507,501,NA,NA,NA,NA,NA,,-0.049430568,0.000988202
704,472,m,wu-yang2008,wu-yang,2008,Short telomeres in patients with chronic schizophrenia who show a poor response to treatment,homo sapiens,Schizophrenia (with poor response to medication vs controls),psychiatric,schizophrenia,none,Mean age = 37.95 (mean duration of illness = 16 years),8011.75,4927.5,adult,44712.5,5840,"68 inpatients with schizophrenia from Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan + 76 age-matched healthy controls",0,NA,0,NA,13778.75,adult,1,adultadult,83,27,both,110,leukocytes,wbcs,southernblot,0,0,NA,1,none,SchizophreniaPatientsWithPoorMedicationResponse.Controls,LTL TRF (kb),negative,0,meanssd,1,NA,NA,NA,NA,-1.196390749,7.41,8.91,NA,NA,0.97,1.36,34,76,NA,NA,NA,NA,NA,,-0.483849007,0.005381539
705,473,m,wu-yang2008,wu-yang,2008,Short telomeres in patients with chronic schizophrenia who show a poor response to treatment,homo sapiens,Schizophrenia (with good response to medication vs controls),psychiatric,schizophrenia,none,Mean age = 38.4 (mean duration of illness = 15.8 years),8249,4927.5,adult,44712.5,5767,"68 inpatients with schizophrenia from Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan + 76 age-matched healthy controls",0,NA,0,NA,14016,adult,1,adultadult,80,30,both,110,leukocytes,wbcs,southernblot,0,0,NA,1,none,SchizophreniaPatientsWithGoodMedicationResponse.Controls,LTL TRF (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.024238166,8.88,8.91,NA,NA,0.9,1.36,34,76,NA,NA,NA,NA,NA,,-0.011200208,0.00917201
706,458,m,zhai2006,zhai,2006,Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study,homo sapiens,Hand osteoarthritis (patients vs controls),disease,other,none,Mean age = 55,20075,4927.5,adult,44712.5,unreported,1086 Caucasian subjects from the TwinsUK Adult Twin Registry,1,zierer2016 + valdes2005,0,NA,20075,adult,1,adultadult,1047,39,both,1086,leukocytes,wbcs,southernblot,0,0,NA,1,negative,HandOsteoarthritis.NoHandOsteoarthritis,Leukocyte TRF (kb),negative,0,meanssd,1,NA,NA,NA,NA,-0.45819862,6.71,7,NA,NA,0.59,0.64,160,926,NA,NA,NA,NA,NA,,-0.160301128,0.000874901
707,321,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily energy intake, kcal",nutrition,carbohydrates,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Daily energy intake, kcal",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.003,NA,NA,NA,NA,,-0.003,0.001801769
708,322,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily protein intake, g",nutrition,protein,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Daily protein intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.006,NA,NA,NA,NA,,-0.006,0.001801672
709,323,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily fat intake, g",nutrition,fats and oils,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Daily fat intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.044,NA,NA,NA,NA,,-0.044,0.001794832
710,324,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily carbohydrate intake, g",nutrition,carbohydrates,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Daily carbohydrate intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.019,NA,NA,NA,NA,,-0.019,0.001800501
711,325,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,Protein % of energy intake,nutrition,protein,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,Protein % of energy intake,Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.023,NA,NA,NA,NA,,-0.023,0.001799896
712,326,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Fat % of energy intake,%",nutrition,fats and oils,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,negative,"Fat % of energy intake,%",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.047,NA,NA,NA,NA,,0.047,0.00179385
713,327,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,Carbohydrate % of energy intake,nutrition,carbohydrates,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,Carbohydrate % of energy intake,Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.022,NA,NA,NA,NA,,-0.022,0.001800058
714,328,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily cereal and cereal production intake, g",nutrition,grains,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Daily cereal and cereal production intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.037,NA,NA,NA,NA,,-0.037,0.001796872
715,329,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily tuber crop intake, g",nutrition,"fruit, legumes and vegetables",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Daily tuber crop intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.025,NA,NA,NA,NA,,-0.025,0.00179955
716,330,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily legumes product intake, g",nutrition,"fruit, legumes and vegetables",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,1,positive,"Daily legumes product intake, g",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.297,NA,NA,NA,NA,,0.297,0.001497951
717,331,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily meat intake, g",nutrition,"meat, fish and eggs",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Daily meat intake, g",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.007,NA,NA,NA,NA,,-0.007,0.001801625
718,332,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Daily dairy products intake, g",nutrition,dairy,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,none,"Daily dairy products intake, g",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.228,NA,NA,NA,NA,,0.228,0.001619341
719,333,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Seeds or nuts,g",nutrition,other,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,1,positive,"Seeds or nuts,g",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.27,NA,NA,NA,NA,,0.27,0.001548675
720,334,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Vegetables, g",nutrition,"fruit, legumes and vegetables",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Vegetables, g",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.058,NA,NA,NA,NA,,0.058,0.0017897
721,335,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Fruits, g/day",nutrition,"fruit, legumes and vegetables",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,0,positive,"Fruits, g/day",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.088,NA,NA,NA,NA,,-0.088,0.001774004
722,336,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Fish and other seafood, g/day",nutrition,"meat, fish and eggs",none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,1,positive,"Fish and other seafood, g/day",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.343,NA,NA,NA,NA,,0.343,0.001402781
723,337,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Seaweed, g/day",nutrition,other,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,1,none,"Seaweed, g/day",Leukocyte telomere length (T/S ratio),positive,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,0.251,NA,NA,NA,NA,,0.251,0.001581923
724,338,m,zhou2016,zhou,2016,"Influence of diet on leukocyte telomere length, markers of inflammation and oxidative stress in individuals with varied glucose tolerance: a Chinese population study",homo sapiens,"Sweetened carbonated beverage, ml/day",nutrition,other,none,Mean = 53.22,19425.3,4927.5,adult,44712.5,unreported,"556 subjects with diabetes, pre-diabetes & normal glucose tolerance recruited from a type 2 diabetes project in a Beijing suburb in China between March 2014 & January 2015.",0,NA,0,NA,19425.3,adult,1,adultadult,343,213,both,556,leukocytes,wbcs,qpcr,0,0,NA,1,negative,"Sweetened carbonated beverage, ml/day",Leukocyte telomere length (T/S ratio),negative,1,correlationcoefficient,1,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,-0.268,NA,NA,NA,NA,,-0.268,0.001552272