SHIKONIN: HOPE FOR INNOVATIVE AND TARGETED CANCER TREATMENTS

Shikonin is a natural compound derived from certain medicinal plants, known for its potential therapeutic effects in cancer treatment. This review examines the therapeutic potential of shikonin, highlighting its origins, chemical structure, and pharmacological properties. We discuss its mechanisms of action, including induction of apoptosis, cell cycle arrest, inhibition of angiogenesis, and suppression of metastasis. Studies reviewed indicate that shikonin not only effectively induces apoptosis in cancer cells but also enhances the efficacy of conventional chemotherapeutics. Moreover, the review explores the potential of shikonin derivatives in optimizing cancer therapy. These findings suggest that shikonin and its derivatives hold considerable promise as effective anticancer agents, warranting further clinical investigation.