ODE models of HSPC population dynamics (A Singh)
contact: apekshasingh@g.ucla.edu

Code for ODE model (Baseline_Model.m) fitting of HSPC count abundances from flow cytometry related for native (Figure 1) and transplant (Figure 4) analysis.
HSPC_FACS_counts are counts data from flow cytometry (Chia JJ, 2024) used as input for model fitting.
Resulting model fits are provided in model_fits.mat

misc: Fitting native IkBKO HSPC counts while penalizing discrepancy between reported wildtype dynamic rates (Busch, K., Klapproth, K., Barile, M. et al. Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature 518, 542–546 (2015). https://doi.org/10.1038/nature14242)