Published December 22, 2022 | Version v1
Project deliverable Open

SIMCor. Deliverable 8.6 - Report on 3D finite element simulations (PHI, M24)

  • 1. ROR icon Philips (Netherlands)


The aim of SIMCor is to establish in-silico methods for testing and validation of cardiovascular implantable devices, such as transcatheter aortic valve implantation (TAVI) prostheses as well as pulmonary artery pressure sensors (PAPS) and make those methods publicly available. In-silico simulations can be used to evaluate the safety, efficacy and applicability of medical devices and thus improve the quality of medical devices launched on the market. For this purpose, a numerical model has been developed in WP8 to perform device implantation and device effect simulations for TAVI. The model contains the patient specific (up until now still synthetic) aortic geometry, the TAVI stent geometry and calcification nodules on the valve leaflets. In an effort to reduce the computation time of the model, the TAVI stent was modelled using beam elements. The validity of this method is tested in a convergence study on a Representative Volume Element (RVE) of the CoreValve TAVI. Furthermore, a simple method to estimate the post-operative risk of paravalvular leakage is introduced. Note that the model described in this deliverable is also used to perform effect simulations used in deliverable D9.2 – Device specific models (BIO, M24) and D7.6 – Proof of principle of the complete virtual patient generator (TUE, M24).


SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices) has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101017578.


SIMCor_D8.6_Report on 3D finite element simulations_PHI_22-12-2022.pdf

Additional details


SIMCOR – In Silico testing and validation of Cardiovascular Implantable devices 101017578
European Commission