In this deliverable we show the validity of a workflow for creating a Reduced-Order Model (ROM), trained by a limited number of high-fidelity deployment model evaluations to generate input for the fast-to-evaluate deployment model developed in D8.8 Fast-to-evaluate TAVI model based on multi-patch NURBS (TUE). The approximate shape of the deployed TAVI stent can be obtained as output of the fast-to-evaluate model. From this shape, patient-specific information like the paravalvular leakage (PVL) area for a selection of cross-sectional planes across the height of the aorta geometry can be obtained. This workflow can be used as a fast tool for pre- operative risk-assessment of the TAVI procedure. The results can be used to decide whether more accurate high- fidelity simulations are needed for a certain patient, thereby significantly reducing the costs of pre-operative risk assessment.

SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices) has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101017578.