deuteration rate (%)									
						1m		5m		15m		1h		4h	
Start	End	Sequence	Modification	Mass	Charge states	PsV	PsV_hep	PsV	PsV_hep	PsV	PsV_hep	PsV	PsV_hep	PsV	PsV_hep
19	51	YKTCKQAGTCPPDIIPKVEGKTIADQILQYGSM	-H2	3593.7932	3-5	51.57(1.04)	50.1(0.55)	53.36(0.77)	52.27(1.05)	55.64(0.72)	53.89(0.6)	56.25(1.14)	55.18(0.64)	57.45(0.86)	56.44(0.7)
19	54	YKTCKQAGTCPPDIIPKVEGKTIADQILQYGSMGVF	-H2	3896.9515	3-5	51.22(0.86)	51.01(0.85)	52.57(0.94)	52.59(1.14)	53.69(0.65)	53.57(0.69)	54.87(1.39)	54.65(0.79)	55.05(0.89)	55.14(0.73)
55	83	FGGLGIGTGSGTGGRTGYIPLGTRPPTAT	No modification	2718.4089	2-4	55.52(0.77)	52.96(1.41)	56.42(1.7)	55.37(0.77)	58(0.52)	56.13(1.08)	59.15(1.84)	58.07(1.36)	59.22(1.77)	58.18(1.3)
84	108	DTLAPVRPPLTVDPVGPSDPSIVSL	No modification	2541.369	2-2	55.72(1.29)	53.88(1.24)	55.39(1.05)	54.53(0.55)	57.41(0.22)	55.46(0.61)	57.58(1.38)	55.29(0.9)	58.6(0.81)	56.39(0.99)
108	114	LVEETSF	No modification	823.3963	1-1	36(1.04)	31.76(0.42)	39.63(1.43)	36.49(0.26)	44.96(0.43)	41.92(0.59)	49.68(1.79)	48.14(2.19)	50.76(0.67)	49.28(1.13)
109	114	VEETSF	No modification	710.3123	1-1	34.31(0.73)	30.11(0.34)	36.63(0.65)	33.46(0.15)	40.64(0.38)	37.53(0.51)	46.28(1.01)	43.55(0.54)	47.61(0.74)	44.94(0.44)
115	132	IDAGAPTSVPSIPPDVSG	No modification	1678.8414	1-2	47.99(0.7)	44.48(0.97)	52.53(1.09)	50.65(0.55)	55.16(0.77)	53.47(0.47)	55.53(0.95)	54.25(0.71)	56.84(0.95)	55.43(0.64)
115	133	IDAGAPTSVPSIPPDVSGF	No modification	1825.9098	1-2	45.6(0.91)	42.28(0.76)	50.51(1.5)	48.75(0.48)	54.08(0.25)	52.52(0.46)	54.93(1.13)	53.96(0.61)	56.11(0.75)	54.67(1.05)
133	146	FSITTSTDTTPAIL	No modification	1466.7504	1-2	38.17(1.41)	33.96(0.52)	40.58(1.14)	36.13(0.52)	44.54(1.06)	39.88(1.47)	48.21(1.13)	44.83(0.71)	53.24(1.22)	49.51(0.98)
134	146	SITTSTDTTPAIL	No modification	1319.682	1-2	38.92(1.13)	34.43(0.83)	40.77(0.87)	36.9(0.93)	42.99(0.59)	39.61(0.23)	46.59(1.06)	43.08(0.7)	51.25(0.98)	47.7(0.7)
147	153	DINNTVT	No modification	775.3712	1-1	64.91(1.46)	63.55(1.34)	64.69(0.74)	64.44(0.59)	64.95(1.33)	64.87(1.26)	65.32(0.59)	64.64(0.85)	65.89(1.01)	64.2(0.27)
147	154	DINNTVTT	No modification	876.4189	1-1	66.6(0.38)	66.03(1.02)	66.93(0.64)	67.12(0.13)	66.7(0.8)	67.39(0.6)	67.23(0.76)	66.49(2.24)	67.13(0.58)	66.66(1.17)
147	181	DINNTVTTVTTHNNPTFTDPSVLQPPTPAETGGHF	No modification	3719.7703	3-3	49.79(1.06)	47.68(0.38)	51.05(0.95)	50.17(0.7)	53.16(0.77)	51.32(0.56)	53.8(1)	52.61(0.57)	55.87(0.49)	54.45(0.82)
182	201	TLSSSTISTHNYEEIPMDTF	No modification	2272.0205	2-2	37.15(1.39)	34.34(0.9)	40.01(1.19)	37.77(0.75)	43.73(0.66)	41.61(0.87)	46.97(1.28)	45.88(0.91)	49.68(0.99)	48.84(1.06)
188	200	ISTHNYEEIPMDT	No modification	1548.6766	2-2	34.36(1.23)	32.54(1.38)	38(1.04)	36.13(0.73)	41.83(1.29)	39.85(0.87)	45.54(1.25)	44(0.88)	47.13(0.25)	45.92(0.58)
188	201	ISTHNYEEIPMDTF	No modification	1695.745	2-2	32.39(1.14)	29.52(1.09)	36.43(1.04)	35.02(0.59)	41.21(1.55)	39.13(0.32)	45.12(1.32)	44.79(0.95)	47.68(1.23)	47.4(1.08)
201	227	FIVSTNPNTVTSSTPIPGSRPVARLGL	No modification	2780.5185	2-3	43.48(1)	41.6(0.51)	50.36(0.92)	48.78(0.88)	55.18(0.73)	52.85(0.6)	58.57(0.96)	56.21(0.75)	62.72(0.74)	60.6(0.64)
202	227	IVSTNPNTVTSSTPIPGSRPVARLGL	No modification	2633.4501	2-3	44.79(1.05)	43.25(0.48)	51.43(0.95)	50.13(0.65)	55.78(0.54)	53.68(0.42)	58.84(1.13)	56.46(0.68)	61.82(0.91)	60.07(0.5)
228	242	YSRTTQQVKVVDPAF	No modification	1737.905	2-3	50.45(1.28)	47.54(0.54)	52.18(1.33)	50.68(0.53)	54.5(0.92)	52.05(0.44)	57.27(1.14)	54.47(0.8)	61.8(1.06)	59.78(0.78)
243	249	VTTPTKL	No modification	758.4538	1-2	71.21(0.96)	70.52(0.41)	71.22(0.53)	70.81(0.26)	71.73(0.38)	71.32(0.23)	71.34(1.09)	70.74(0.4)	71.47(0.74)	70.91(0.45)
243	266	VTTPTKLITYDNPAYEGIDVDNTL	No modification	2652.317	2-4	62.54(0.85)	62.7(0.85)	62.85(1.35)	62.9(0.94)	64.31(1.32)	63.66(0.53)	64.4(1.2)	63.68(0.39)	64.61(0.58)	63.9(0.71)
250	261	ITYDNPAYEGID	No modification	1369.6038	1-2	58.83(1.31)	58.52(1.03)	58.86(1.62)	58.86(1.07)	59.54(0.64)	58.8(0.08)	59.05(1.33)	58.84(1.3)	59.29(1.09)	58.88(1.17)
250	266	ITYDNPAYEGIDVDNTL	No modification	1911.8738	1-2	59.21(0.99)	58.32(0.58)	58.88(1.74)	58.87(1.13)	60.02(0.88)	59.28(0.63)	59.67(1.5)	58.99(0.81)	60.22(1.32)	59.33(0.81)
267	283	YFSSNDNSINIAPDPDF	No modification	1914.8272	1-2	52.36(1.63)	52.33(1.09)	52.1(1.49)	52.05(0.9)	53.78(1.01)	52.99(0.59)	53.21(1.82)	52.22(0.69)	53.95(0.96)	53.1(1.65)
267	284	YFSSNDNSINIAPDPDFL	No modification	2027.9112	2-3	51.56(1.85)	50.78(0.96)	51.36(0.82)	51.01(1.56)	52.55(0.32)	52.14(0.57)	53.07(1.79)	52.43(0.7)	53.76(1.1)	52.19(1.49)
268	283	FSSNDNSINIAPDPDF	No modification	1751.7639	1-2	54.03(1.28)	54.56(0.57)	54.95(1.86)	54.11(2.08)	54.51(0.21)	54.36(1.09)	54.12(0.97)	53.69(0.99)	53.97(1.15)	54.3(0.32)
268	284	FSSNDNSINIAPDPDFL	No modification	1864.8479	1-2	52.68(1.05)	51.61(1.55)	52.07(1.39)	52.66(0.97)	54.51(0.63)	53.32(0.28)	53.96(1.69)	53.7(0.6)	54.38(1.15)	53.79(1.32)
331	338	STIDPAEE	No modification	860.3763	1-1	60.17(0.9)	59.99(0.46)	59.97(1.34)	60.13(0.96)	60.28(0.55)	59.94(0.52)	60.9(1.1)	59.63(1.4)	60.98(0.43)	59.99(0.35)
339	365	IELQTITPSTYTTTSHAASPTSINNGL	No modification	2817.4032	2-3	59.71(1.02)	58.4(0.6)	63.13(1.21)	62.63(0.98)	65.11(0.99)	64.4(0.6)	65.51(1.21)	65.13(0.78)	65.95(0.9)	65.5(0.79)
339	372	IELQTITPSTYTTTSHAASPTSINNGLYDIYADD	No modification	3672.7319	2-3	52(1.15)	50.3(0.79)	56.69(1.41)	56.18(1.18)	60.61(0.94)	58.86(0.5)	61.45(1.37)	61.03(0.87)	62.27(0.76)	61.87(0.8)
342	365	QTITPSTYTTTSHAASPTSINNGL	No modification	2462.1925	2-2	58.16(1.12)	56.51(0.62)	62.28(1.25)	61.33(0.93)	64.6(0.91)	63.66(0.44)	64.81(1.19)	64.35(0.55)	65.32(1.03)	64.65(0.77)
342	372	QTITPSTYTTTSHAASPTSINNGLYDIYADD	No modification	3317.5212	2-5	50.92(0.96)	49.16(0.77)	56.49(1.2)	55.45(1.16)	60.12(1.34)	58.6(0.88)	61.06(1.5)	60.95(0.94)	62.5(0.85)	61.76(0.88)
349	365	YTTTSHAASPTSINNGL	No modification	1733.822	2-2	50.83(1.5)	47.98(0.42)	56.94(1.58)	55.28(0.61)	59.62(0.58)	58.42(0.31)	60.23(1.28)	59.97(0.66)	60.53(1.27)	59.67(0.78)
366	372	YDIYADD	No modification	873.3392	1-1	36.41(1.62)	32.13(0.71)	42.47(1.54)	40.54(0.53)	46.65(1.21)	44.36(0.43)	50.84(1.54)	48.44(1.03)	52.09(1.22)	50.44(1.04)
373	390	FITDTSTTPVPSVPSTSL	No modification	1848.9357	1-2	63.07(1.34)	63.69(1.1)	61.99(1.08)	63.3(0.7)	63.24(1.31)	62.59(1.29)	63.21(1.68)	62.94(1.18)	64.36(1.67)	64.1(0.76)
391	427	SGYIPANTTIPFGGAYNIPLVSGPDIPINITDQAPSL	No modification	3782.9407	2-3	56.74(0.77)	53.9(1.22)	61.29(0.95)	60.7(0.97)	63.4(1.26)	62.51(0.38)	63.54(1.23)	63.67(1.22)	63.41(0.91)	63.6(1.09)
406	427	YNIPLVSGPDIPINITDQAPSL	No modification	2336.2264	2-2	54.31(0.28)	50.11(1.64)	59.05(1.3)	57.93(0.76)	62.24(0.01)	61.21(1.27)	62.77(0.73)	62.67(0.94)	63.18(1.41)	62.54(1.29)
428	437	IPIVPGSPQY	No modification	1069.5808	1-2	57.16(1.73)	53.18(0.36)	62.21(1.53)	62.58(0.6)	64.12(1.37)	65.1(1.18)	66(1.19)	66.25(0.64)	64.91(1.3)	66.16(0.48)
428	440	IPIVPGSPQYTII	No modification	1396.7966	1-2	54.96(0.33)	50.96(0.27)	61.5(0.9)	59.95(1.18)	65.97(0.91)	63.58(0.24)	67.84(1.33)	66.69(1.18)	67.76(1.15)	67.64(0.8)
441	446	ADAGDF	No modification	594.2286	1-1	36.04(1.56)	29.86(0.26)	42.96(1.38)	38.93(1.15)	45.6(0.96)	44.32(1.29)	49.98(2.48)	47.5(4.14)	49.2(1.64)	47.85(1.44)
446	452	FYLHPSY	No modification	925.4334	1-2	34.5(1.02)	34.44(0.32)	44.74(2.05)	43.69(1.21)	51.47(1.14)	49.95(0.6)	55.93(1.2)	54.86(1.39)	57.63(0.86)	56.63(1.84)
447	452	YLHPSY	No modification	778.365	1-2	34.58(1.69)	34.56(0.47)	44.41(1.67)	45.2(1.1)	51.42(0.65)	51.01(0.37)	56.3(1.3)	55.64(0.88)	58.87(1.22)	59.1(1.46)
454	465	MLRKRRKRLPYF	No modification	1662.998	3-4	44.15(2.21)	43.72(0.8)	45.5(2.44)	45.25(0.61)	46.81(0.87)	48.43(0.35)	47.62(2.15)	48.01(1.01)	47.6(1)	48(1.55)
466	471	FSDVSL	No modification	666.3225	1-1	55.81(0.71)	55.11(0.68)	55.7(2.32)	55.43(2.25)	57.3(1.4)	56.14(0.89)	56.52(1.17)	56.47(1.16)	57.76(1.25)	55.78(0.75)
466	473	FSDVSLAA	No modification	808.3967	1-1	54.57(0.92)	52.73(0.36)	54.93(1.39)	54.2(0.39)	55.92(1.18)	54.42(0.4)	55.35(1.53)	54.12(0.97)	55.51(0.7)	54.22(0.87)
469	473	VSLAA	No modification	459.2693	1-1	61.33(1.04)	59.08(1.34)	62.42(1.43)	62.6(1.05)	61.83(0.2)	63.38(1.82)	63.24(1.35)	62.31(3.04)	63.05(1)	61.5(0.74)