Pleomorphic Adenoma mimicking Schwannoma-Like phenotype: A Case Report
Contributors
Researchers:
- 1. Department of Oral and Maxillofacial Pathology, Ibn Sina National College for Medical College for Medical Studies, Jeddah, Kingdom of Saudi Arabia (KSA)
- 2. Medical Studies, Jeddah, Kingdom of Saudi Arabia (KSA), Department of Oral and Maxillofacial Rehabilitation, Ibn Sina National College for Medical College for Medical Studies, Jeddah, Kingdom of Saudi Arabia (KSA)
- 3. Medical Officer-Indian Cancer Society, Parel, Mumbai, India
Description
ABSTRACT:
The schwannoma-like pleomorphic adenoma is a rare histopathological variant of the pleomorphic
adenoma. It can occur in any salivary gland; however it is most commonly detected in the parotid.
Pleomorphic adenomas are well-known for their cytomorphological and architectural variability, which
is characterised by the presence of intermixed epithelial and mesenchymal-like components. We
present a rare case of parotid gland pleomorphic adenoma with prominent schwannoma-like
characteristics that mimicked a benign schwannoma. The tumour had a high prevalence (about 80%) of
schwannoma-like regions with a localised (approximately 20%) epithelial component along with
tubular organisation. Only 8 cases of schwannoma-like pleomorphic adenoma have been documented
in the literature, to the best of our knowledge. The differential diagnosis between this entity and
neurogenic and myogenic tumors is discussed.
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Additional details
Dates
- Accepted
-
2023-12-26
References
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