Effect of aloe vera hydrogel on the palatal wound after harvesting free gingival graft

Introduction: Several studies have used aloe vera hydrogel to enhance various tissues regeneration and accelerate wound healing.

Materials and Methods: In this study, hydrogel was prepared from aloe vera extract and the pH level and viscosity were measured. a sterility test of the substance was done. then it was applied on the donor site of the palate of 11 patients after free gingival graft harvesting procedure, healing and re-epithelialization was monitored and compared with 11 patients who underwent the same operation but while observing natural healing and re-epithelialization in the area.

Results: The intervention group surpassed the control group during the follow-ups of healing index after (two weeks, three weeks, one month), and the P value was less than 0.05. The intervention group surpassed the control group with statistically significant differences during follow-ups of re-epithelialization in the region after a month, and the P value was equal to 0.034, while the differences were not statistically significant during the rest of the periods.

Conclusions: The aloe vera hydrogel used in the study accelerated the healing and re-epithelialization in the donor site in the palate