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SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton

Tzur, Yonatan B.; Wilson, Katherine L.; Gruenbaum, Yosef


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  <dc:creator>Tzur, Yonatan B.</dc:creator>
  <dc:creator>Wilson, Katherine L.</dc:creator>
  <dc:creator>Gruenbaum, Yosef</dc:creator>
  <dc:date>2006-08-23</dc:date>
  <dc:description>The novel SUN-domain family of nuclear envelope proteins interacts with various KASH-domain partners to form SUN-domain-dependent 'bridges' across the inner and outer nuclear membranes. These bridges physically connect the nucleus to every major component of the cytoskeleton. SUN-domain proteins have diverse roles in nuclear positioning, centrosome localization, germ-cell development, telomere positioning and apoptosis. By serving both as mechanical adaptors and nuclear envelope receptors, we propose that SUN-domain proteins connect cytoplasmic and nucleoplasmic activities.</dc:description>
  <dc:identifier>https://zenodo.org/record/999029</dc:identifier>
  <dc:identifier>10.1038/nrm2003</dc:identifier>
  <dc:identifier>oai:zenodo.org:999029</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:title>SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>
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