Journal article Open Access

SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton

Tzur, Yonatan B.; Wilson, Katherine L.; Gruenbaum, Yosef


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{
  "@context": "https://schema.org/", 
  "@id": "https://doi.org/10.1038/nrm2003", 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Tzur, Yonatan B."
    }, 
    {
      "@type": "Person", 
      "name": "Wilson, Katherine L."
    }, 
    {
      "@type": "Person", 
      "name": "Gruenbaum, Yosef"
    }
  ], 
  "datePublished": "2006-08-23", 
  "description": "The novel SUN-domain family of nuclear envelope proteins interacts with various KASH-domain partners to form SUN-domain-dependent 'bridges' across the inner and outer nuclear membranes. These bridges physically connect the nucleus to every major component of the cytoskeleton. SUN-domain proteins have diverse roles in nuclear positioning, centrosome localization, germ-cell development, telomere positioning and apoptosis. By serving both as mechanical adaptors and nuclear envelope receptors, we propose that SUN-domain proteins connect cytoplasmic and nucleoplasmic activities.", 
  "headline": "SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton", 
  "identifier": "https://doi.org/10.1038/nrm2003", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "license": "", 
  "name": "SUN-domain proteins: 'Velcro' that links the nucleoskeleton to the cytoskeleton", 
  "url": "https://zenodo.org/record/999029"
}
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