INVITRO STUDIES ON THE EFFECT OF CURCUMA LONGA METHANOL EXTRACTS IN COLORECTAL HCT – 116 CELL LINES

The leaves of Curcuma longa is commonly known as gummy gardenia/cambi gum tree. It is traditional medicinal plant grown in India, have many medicinal and therapeutic properties in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis. This leaf extracts are found to have antioxidant, chemopreventive agents, anti-inflammatory and anti cancer activities. Curcumin is the active principle which is responsible for anticancer effects. This work was aimed to study the effect of Curcuma longa methanol extracts on HCT116 cell lines. It was found methanolic extracts of Curcuma longa leaves has phytochemical compounds having good inhibitory scavenging and anticancer activities. Keywords: Curcuma longa, HCT116 cell line, Curcumin