10.1097/jcp.0000000000000455
https://zenodo.org/records/890747
oai:zenodo.org:890747
Pies, Ronald W.
Ronald W.
Pies
Antidepressants: Conundrums and Complexities of Efficacy Studies
Zenodo
2016
2016-02-01
Other (Open)
It is by now a truism in the lay press that "antidepressants are no more effective than sugar pills." Although the best available evidence does not support this conclusion, 2–4 public skepticism regarding the efficacy of antidepressants is understandable, given several recent developments. Furthermore, concerns over possible adverse effects of antidepressants, including increased risk of "suicidality" in younger populations, have continued to darken the public's perception of these agents.