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Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds

Leila Lefrada; Randolf D. Köhn; Souhila Malki; Wissam Mazouz; Ahcene Bouchemma; Meriem Hadjem

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<oai_dc:dc xmlns:dc="" xmlns:oai_dc="" xmlns:xsi="" xsi:schemaLocation="">
  <dc:creator>Leila Lefrada</dc:creator>
  <dc:creator>Randolf D. Köhn</dc:creator>
  <dc:creator>Souhila Malki</dc:creator>
  <dc:creator>Wissam Mazouz</dc:creator>
  <dc:creator>Ahcene Bouchemma</dc:creator>
  <dc:creator>Meriem Hadjem</dc:creator>
  <dc:description>This work describes the synthesis, spectroscopic, structural characterization and antibacterial activities of new saturated heterocyclic nitrogen compounds of the 1, 3, 5-triazacyclohexane type.

     The new triazacyclohexanes (R3TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:1 mixture of 4-iodoaniline and 2-ethyl1-hexyl amine with formalin. The synthesized compounds were characterized by spectral analysis IR, 1H NMR and 13C NMR and shown to be mainly a mixture of the two mixed triazacylcohexane.

    These compounds were screened for their antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.



  <dc:source>Algerian Journal of Natural Products 5(2) 463 - 468</dc:source>
  <dc:subject>antibacterial activity</dc:subject>
  <dc:title>Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds</dc:title>
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