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Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds

Leila Lefrada; Randolf D. Köhn; Souhila Malki; Wissam Mazouz; Ahcene Bouchemma; Meriem Hadjem


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{
  "description": "<p>This work describes the synthesis, spectroscopic, structural characterization and antibacterial activities of new saturated heterocyclic nitrogen compounds of the 1, 3, 5-triazacyclohexane type.</p>\n\n<p>\u00a0\u00a0\u00a0 \u00a0The new triazacyclohexanes (R<sub>3</sub>TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:1 mixture of 4-iodoaniline and 2-ethyl1-hexyl amine with formalin. The synthesized compounds were characterized by spectral analysis IR, <sup>1</sup>H NMR and <sup>13</sup>C NMR and shown to be mainly a mixture of the two mixed triazacylcohexane.</p>\n\n<p>\u00a0\u00a0\u00a0 These compounds were screened for their antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.</p>\n\n<p>\u00a0</p>\n\n<p>\u00a0</p>\n\n<p>\u00a0</p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "affiliation": "Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria", 
      "@type": "Person", 
      "name": "Leila Lefrada"
    }, 
    {
      "affiliation": "Departement of Chemistry University of Bath, Bath, BA2 7AY, UK", 
      "@type": "Person", 
      "name": "Randolf D. K\u00f6hn"
    }, 
    {
      "affiliation": "Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria", 
      "@type": "Person", 
      "name": "Souhila Malki"
    }, 
    {
      "affiliation": "D\u00e9partement de Biologie, Facult\u00e9 des Sciences, Universit\u00e9 Badji Mokhtar, 2300 Annaba, Alg\u00e9rie.", 
      "@type": "Person", 
      "name": "Wissam Mazouz"
    }, 
    {
      "affiliation": "Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria", 
      "@type": "Person", 
      "name": "Ahcene Bouchemma"
    }, 
    {
      "affiliation": "Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria", 
      "@type": "Person", 
      "name": "Meriem Hadjem"
    }
  ], 
  "headline": "Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2017-09-11", 
  "url": "https://zenodo.org/record/889066", 
  "keywords": [
    "synthesis", 
    "triazacyclohexanes", 
    "antibacterial activity"
  ], 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.5281/zenodo.889066", 
  "@id": "https://doi.org/10.5281/zenodo.889066", 
  "@type": "ScholarlyArticle", 
  "name": "Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds"
}
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