Journal article Open Access

Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds

Leila Lefrada; Randolf D. Köhn; Souhila Malki; Wissam Mazouz; Ahcene Bouchemma; Meriem Hadjem


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  <identifier identifierType="DOI">10.5281/zenodo.889066</identifier>
  <creators>
    <creator>
      <creatorName>Leila Lefrada</creatorName>
      <affiliation>Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria</affiliation>
    </creator>
    <creator>
      <creatorName>Randolf D. Köhn</creatorName>
      <affiliation>Departement of Chemistry University of Bath, Bath, BA2 7AY, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Souhila Malki</creatorName>
      <affiliation>Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria</affiliation>
    </creator>
    <creator>
      <creatorName>Wissam Mazouz</creatorName>
      <affiliation>Département de Biologie, Faculté des Sciences, Université Badji Mokhtar, 2300 Annaba, Algérie.</affiliation>
    </creator>
    <creator>
      <creatorName>Ahcene Bouchemma</creatorName>
      <affiliation>Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria</affiliation>
    </creator>
    <creator>
      <creatorName>Meriem Hadjem</creatorName>
      <affiliation>Faculty of Exact Sciences, Department of Material Science, University Larbi Ben M'hidi of Oum El Bouaghi, Rue de Constantine, 04000, Algeria</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2017</publicationYear>
  <subjects>
    <subject>synthesis</subject>
    <subject>triazacyclohexanes</subject>
    <subject>antibacterial activity</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2017-09-11</date>
  </dates>
  <resourceType resourceTypeGeneral="JournalArticle"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/889066</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.889065</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;This work describes the synthesis, spectroscopic, structural characterization and antibacterial activities of new saturated heterocyclic nitrogen compounds of the 1, 3, 5-triazacyclohexane type.&lt;/p&gt;

&lt;p&gt;     The new triazacyclohexanes (R&lt;sub&gt;3&lt;/sub&gt;TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:1 mixture of 4-iodoaniline and 2-ethyl1-hexyl amine with formalin. The synthesized compounds were characterized by spectral analysis IR, &lt;sup&gt;1&lt;/sup&gt;H NMR and &lt;sup&gt;13&lt;/sup&gt;C NMR and shown to be mainly a mixture of the two mixed triazacylcohexane.&lt;/p&gt;

&lt;p&gt;    These compounds were screened for their antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.&lt;/p&gt;

&lt;p&gt; &lt;/p&gt;

&lt;p&gt; &lt;/p&gt;

&lt;p&gt; &lt;/p&gt;</description>
  </descriptions>
</resource>
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