Journal article Open Access

Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds

Leila Lefrada; Randolf D. Köhn; Souhila Malki; Wissam Mazouz; Ahcene Bouchemma; Meriem Hadjem


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{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.889066", 
  "container_title": "Algerian Journal of Natural Products", 
  "title": "Antibacterial Activities of New Saturated Heterocyclic Nitrogen Compounds", 
  "issued": {
    "date-parts": [
      [
        2017, 
        9, 
        11
      ]
    ]
  }, 
  "abstract": "<p>This work describes the synthesis, spectroscopic, structural characterization and antibacterial activities of new saturated heterocyclic nitrogen compounds of the 1, 3, 5-triazacyclohexane type.</p>\n\n<p>\u00a0\u00a0\u00a0 \u00a0The new triazacyclohexanes (R<sub>3</sub>TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:1 mixture of 4-iodoaniline and 2-ethyl1-hexyl amine with formalin. The synthesized compounds were characterized by spectral analysis IR, <sup>1</sup>H NMR and <sup>13</sup>C NMR and shown to be mainly a mixture of the two mixed triazacylcohexane.</p>\n\n<p>\u00a0\u00a0\u00a0 These compounds were screened for their antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.</p>\n\n<p>\u00a0</p>\n\n<p>\u00a0</p>\n\n<p>\u00a0</p>", 
  "author": [
    {
      "family": "Leila Lefrada"
    }, 
    {
      "family": "Randolf D. K\u00f6hn"
    }, 
    {
      "family": "Souhila Malki"
    }, 
    {
      "family": "Wissam Mazouz"
    }, 
    {
      "family": "Ahcene Bouchemma"
    }, 
    {
      "family": "Meriem Hadjem"
    }
  ], 
  "page": "463 - 468", 
  "volume": "5", 
  "type": "article-journal", 
  "issue": "2", 
  "id": "889066"
}
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