8600
doi
10.1159/000356333
oai:zenodo.org:8600
user-inmind
user-eu
Molecular imaging in sporadic and at genetically risk populations of Alzheimer´s disease
Nordberg, Agneta
Karolinska Institutet, Alzheimer Neurobiology Center, Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm , Sweden
info:eu-repo/semantics/restrictedAccess
Positron emission tomography ·· · · ·
Molecular imaging
Positron emission tomography tracers
Amyloid
Alzheimer’s disease
Mild cognitive impairment
<p>The time course and order of the pathological-physiological processes in Alzheimer’s disease (AD) are still under investigation and it is expected that molecular imaging will provide important insight into early brain pathology. Multi-tracer positron emission tomography studies visualizing fibrillar amyloid, inflammatory changes including astrocytosis and activation of microglia as well as cerebral glucose metabolism indicate that AD pathological processes are initiated and ongoing decades before the onset of cognitive symptoms. Therefore, prevention might be a new promising target for AD therapy.</p>
Zenodo
2014-01-09
info:eu-repo/semantics/article
643061
user-inmind
user-eu
award_title=Imaging of Neuroinflammation in Neurodegenerative Diseases; award_number=278850; award_identifiers_scheme=url; award_identifiers_identifier=https://cordis.europa.eu/projects/278850; funder_id=00k4n6c32; funder_name=European Commission;
1579525115.504789
public
Neurodegener Dis.
13
2-3
160-2
2014-01-09