Published February 19, 2014 | Version v1
Journal article Restricted

Dendrimersomes: a new vesicular nano-platform for MR-Molecular Imaging applications

  • 1. Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza 52, 10126 Torino, Italy.
  • 2. Dipartimento di Scienze e Innovazione Tecnologica, Universita` del Piemonte Orientale ‘‘Amedeo Avogadro’’, Viale T. Michel 11, 15121, Alessandria, Italy.
  • 3. Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza 52, 10126 Torino, Italy and Porto Conte Ricerche S.r.l., SP 55 Porto Conte/Capo Caccia Km 8.400, Loc Tramariglio 07041 Alghero (SS), Italy
  • 4. Department of Molecular Biotechnology and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza 52, 10126 Torino, Italy and Center for Preclinical Imaging, University of Torino, Via Ribes 5, 10010 Colleretto Giacosa (TO), Italy

Description

A new class of nanovesicles formed by the self-assembly of amphiphilic Janus dendrimers, dendrimersomes, loaded with hydrophilic or amphiphilic magnetic resonance imaging chelates shows promising properties as a novel, efficient and versatile nano platform for biomedical imaging.

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Funding

INMIND – Imaging of Neuroinflammation in Neurodegenerative Diseases 278850
European Commission