Software Open Access
Adaptive Immunity Group
DISCLAIMER You are free to use VDJdb in research studies for the purpose of RepSeq sample and T-cell clonotype list annotation. However, the authors request priority in publishing a meta-analysis of the dataset aggregated and stored here. This message will be removed once VDJdb is officially published in a peer-review journal.
The primary goal of VDJdb is to facilitate access to existing information on T-cell receptor antigen specificities, i.e. the ability to recognize certain epitopes in certain MHC contexts.
Our mission is to both aggregate the scarce TCR specificity information available so far and to create a curated repository to store such data.
In addition to routine database updates providing the most up-to-date information, we make our best to ensure data consistency and fight irregularities in TCR specificity reporting with a complex database validation scheme:
We've added a large dataset of paired alpha-beta TCR sequences from mouse and human subjects. The database now contains more than a thousand records for Mus Musculus, a species that was nearly absent in previous versions.