Published July 29, 2014 | Version v1.0
Dataset Open

Modeling of the SEA complex, a modulator of the TORC1 pathway

Creators

  • 1. CNRS UMR 8126, Universite Paris-Sud 11, Institut Gustave Roussy, France
  • 2. The Rockefeller University, United States
  • 3. University of California, United States

Contributors

Data manager:

  • 1. University of California San Francisco

Description

These scripts demonstrate the use of IMP, MODELLER, and PMI in the modeling of the SEA complex using 188 DSS chemical cross-links and 23 composites from affinity purification.

First, MODELLER is used to generate initial structures for the individual components where reliable templates are available. Then, IMP / PMI are used to model these components using the DSS crosslinks and the affinity purification data for the entire SEA complex.

For more information about how to reproduce this modeling, see https://salilab.org/sea or the README file.

Files

integrativemodeling/sea-v1.0.zip

Files (58.4 MB)

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Additional details

Related works

Is supplement to
https://github.com/integrativemodeling/sea/tree/v1.0 (URL)
25073740 (PMID)
https://salilab.org/sea (URL)