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        Note that additional data was saved in multiqc_danRer10_data when this report was generated.


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        If you use plots from MultiQC in a publication or presentation, please cite:

        MultiQC: Summarize analysis results for multiple tools and samples in a single report
        Philip Ewels, Måns Magnusson, Sverker Lundin and Max Käller
        Bioinformatics (2016)
        doi: 10.1093/bioinformatics/btw354
        PMID: 27312411

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        About MultiQC

        This report was generated using MultiQC, version 1.14

        You can see a YouTube video describing how to use MultiQC reports here: https://youtu.be/qPbIlO_KWN0

        For more information about MultiQC, including other videos and extensive documentation, please visit http://multiqc.info

        You can report bugs, suggest improvements and find the source code for MultiQC on GitHub: https://github.com/ewels/MultiQC

        MultiQC is published in Bioinformatics:

        MultiQC: Summarize analysis results for multiple tools and samples in a single report
        Philip Ewels, Måns Magnusson, Sverker Lundin and Max Käller
        Bioinformatics (2016)
        doi: 10.1093/bioinformatics/btw354
        PMID: 27312411

        These samples were run by seq2science v1.0.0, a tool for easy preprocessing of NGS data.

        Take a look at our docs for info about how to use this report to the fullest.

        Workflow
        atac-seq
        Date
        June 16, 2023
        Project
        atac
        Contact E-mail
        yourmail@here.com

        Report generated on 2023-06-16, 16:17 CEST based on data in:

        Change sample names:


        General Statistics

        Showing 23/23 rows and 17/34 columns.
        Sample Name% DuplicationM Reads After FilteringGC content% PF% AdapterInsert Size% Dups% MappedM Total seqs% Proper PairsM Total seqs% AssignedGenome coverageM Genome readsM MT genome readsNumber of PeaksTreatment Redundancy
        GSM4661977
        11.4%
        154.0
        41.8%
        96.4%
        12.1%
        376 bp
        24.0%
        99.6%
        154.0
        93.3%
        13.2
        30.1%
        15.9 X
        152.8
        2.0
        29717
        0.22
        GSM4661978
        12.3%
        156.2
        41.6%
        96.8%
        11.8%
        373 bp
        24.8%
        99.6%
        156.2
        93.2%
        13.1
        29.7%
        16.2 X
        154.7
        2.2
        28950
        0.22
        GSM4661979
        3.1%
        30.2
        45.7%
        94.4%
        34.7%
        205 bp
        10.7%
        99.2%
        30.2
        97.5%
        9.3
        67.8%
        2.8 X
        29.9
        0.5
        108472
        0.29
        GSM4661980
        10.5%
        62.1
        43.6%
        95.0%
        40.1%
        191 bp
        23.3%
        99.5%
        62.1
        97.4%
        16.7
        48.1%
        5.3 X
        60.1
        2.5
        123365
        0.22
        GSM4661981
        10.0%
        67.0
        43.5%
        95.4%
        40.8%
        191 bp
        22.6%
        99.1%
        67.0
        97.3%
        17.7
        42.8%
        5.8 X
        65.9
        1.5
        108282
        0.20
        GSM4661982
        14.3%
        34.0
        41.3%
        99.3%
        21.4%
        171 bp
        21.9%
        99.4%
        34.0
        97.2%
        6.4
        5.2%
        3.5 X
        34.0
        0.2
        16798
        0.04
        GSM4661983
        2.5%
        40.4
        41.6%
        95.2%
        40.9%
        187 bp
        7.8%
        99.2%
        40.4
        96.8%
        12.1
        7.1%
        3.6 X
        40.1
        0.6
        50249
        0.05
        GSM4661984
        3.5%
        48.2
        41.6%
        95.4%
        38.8%
        191 bp
        10.3%
        99.4%
        48.2
        96.5%
        13.4
        9.2%
        4.2 X
        46.4
        2.4
        42755
        0.06
        GSM4661985
        18.3%
        218.8
        40.7%
        98.1%
        25.3%
        234 bp
        31.7%
        99.5%
        218.8
        96.7%
        34.8
        9.7%
        20.6 X
        205.0
        15.1
        76537
        0.09
        GSM4661986
        4.1%
        76.2
        42.2%
        95.3%
        41.8%
        168 bp
        13.1%
        99.3%
        76.2
        97.2%
        22.8
        13.0%
        6.6 X
        75.2
        1.7
        89947
        0.10
        GSM4661987
        12.3%
        32.7
        40.7%
        99.5%
        31.5%
        175 bp
        21.2%
        99.4%
        32.7
        98.0%
        7.7
        6.2%
        3.2 X
        32.8
        0.1
        21448
        0.03
        GSM4661988
        3.8%
        78.3
        42.5%
        94.7%
        43.9%
        164 bp
        12.3%
        99.4%
        78.3
        97.3%
        24.3
        15.8%
        6.8 X
        77.5
        1.6
        90386
        0.10
        GSM4661989
        10.9%
        216.2
        40.8%
        98.4%
        22.0%
        255 bp
        19.9%
        99.6%
        216.2
        96.7%
        36.0
        16.7%
        21.5 X
        213.6
        4.1
        78533
        0.12
        GSM4661990
        5.2%
        45.7
        41.1%
        95.1%
        39.1%
        188 bp
        15.7%
        99.4%
        45.7
        97.5%
        13.2
        32.4%
        3.6 X
        40.3
        5.8
        51203
        0.16
        GSM4661991
        13.0%
        153.7
        42.3%
        96.5%
        14.3%
        377 bp
        27.3%
        99.4%
        153.7
        95.6%
        16.6
        66.4%
        15.5 X
        149.2
        4.8
        71502
        0.44
        GSM4661992
        17.8%
        81.0
        41.7%
        99.3%
        25.8%
        170 bp
        27.5%
        99.7%
        81.0
        98.3%
        16.7
        17.8%
        8.1 X
        80.8
        0.7
        77593
        0.09
        GSM4661993
        18.0%
        40.9
        41.5%
        99.3%
        26.6%
        168 bp
        27.7%
        99.8%
        40.9
        98.5%
        8.9
        15.9%
        4.1 X
        40.9
        0.2
        52263
        0.06
        GSM4661994
        3.6%
        50.8
        41.9%
        96.9%
        45.8%
        154 bp
        9.8%
        99.5%
        50.8
        97.6%
        16.8
        11.4%
        4.4 X
        48.8
        2.5
        67315
        0.07
        GSM4661995
        11.7%
        325.6
        41.3%
        98.1%
        26.5%
        234 bp
        20.3%
        99.6%
        325.6
        97.0%
        60.9
        6.7%
        31.8 X
        319.5
        8.7
        122266
        0.11
        GSM4661996
        3.6%
        28.6
        45.1%
        97.2%
        37.1%
        156 bp
        11.8%
        99.3%
        28.6
        97.5%
        8.6
        22.7%
        2.6 X
        28.3
        0.7
        59157
        0.10
        GSM4661997
        10.3%
        181.3
        42.3%
        97.6%
        16.1%
        313 bp
        21.8%
        99.5%
        181.3
        95.4%
        23.0
        36.8%
        18.7 X
        181.3
        1.0
        78829
        0.24
        GSM4661998
        2.5%
        35.9
        42.6%
        93.9%
        26.3%
        267 bp
        8.4%
        99.2%
        35.9
        93.0%
        7.2
        13.5%
        3.5 X
        36.2
        0.2
        32100
        0.07
        GSM4661999
        9.9%
        212.2
        42.6%
        97.9%
        15.7%
        342 bp
        21.3%
        99.4%
        212.2
        93.6%
        21.9
        18.4%
        21.6 X
        209.5
        3.9
        80222
        0.15

        Workflow explanation

        Preprocessing of reads was done automatically by seq2science v1.0.0 using the atac-seq workflow. Genome assembly rCheMyd1.pri was downloaded with genomepy 0.15.0. Paired-end reads were trimmed with fastp v0.23.2 with default options. Reads were aligned with bwa-mem2 v2.2.1 with options '-M'. Afterwards, duplicate reads were marked with Picard MarkDuplicates v3.0.0. General alignment statistics were collected by samtools stats v1.16. Before peak calling, paired-end info from reads was removed with seq2science so that both mates in a pair get used. Peaks were called with macs2 v2.2.7 with options '--shift -100 --extsize 200 --nomodel --buffer-size 10000' in BAM mode. The effective genome size was estimated by by khmer v3.0 by taking the number of unique k-mers in the assembly of the same length as the average read length for each sample. Deeptools v3.5.1 was used for the fingerprint, profile, correlation and dendrogram/heatmap plots, where the heatmap was made with options '--distanceBetweenBins 9000 --binSize 1000'. Narrowpeak files of biological replicates belonging to the same condition were merged with fisher's method in macs2. The fraction reads in peak score (frips) was calculated by featurecounts v1.6.4. The UCSC genome browser was used to visualize and inspect alignment. A consensus set of summits was made with gimmemotifs.combine_peaks v0.18.0. A peak feature distribution plot and peak localization plot relative to TSS were made with chipseeker. All summits were extended with 100 bp to get a consensus peakset. Finally, a count table from the consensus peakset was made with gimmemotifs.coverage_table. Differential motif analysis on the consensus peakset was performed with gimme maelstrom v0.18.0. Quality control metrics were aggregated by MultiQC v1.14.

        Assembly stats

        Genome assembly danRer10 contains of 1061 contigs, with a GC-content of 36.64%, and 0.15% consists of the letter N. The N50-L50 stats are 53345113-12 and the N75-L75 stats are 47771147-18. The genome annotation contains 32762 genes.

        fastp

        fastp An ultra-fast all-in-one FASTQ preprocessor (QC, adapters, trimming, filtering, splitting...).DOI: 10.1093/bioinformatics/bty560.

        Filtered Reads

        Filtering statistics of sampled reads.

        loading..

        Insert Sizes

        Insert size estimation of sampled reads.

        loading..

        Sequence Quality

        Average sequencing quality over each base of all reads.

        loading..

        GC Content

        Average GC content over each base of all reads.

        loading..

        N content

        Average N content over each base of all reads.

        loading..

        Picard

        Picard is a set of Java command line tools for manipulating high-throughput sequencing data.

        Insert Size

        Plot shows the number of reads at a given insert size. Reads with different orientations are summed.

        loading..

        Mark Duplicates

        Number of reads, categorised by duplication state. Pair counts are doubled - see help text for details.

        The table in the Picard metrics file contains some columns referring read pairs and some referring to single reads.

        To make the numbers in this plot sum correctly, values referring to pairs are doubled according to the scheme below:

        • READS_IN_DUPLICATE_PAIRS = 2 * READ_PAIR_DUPLICATES
        • READS_IN_UNIQUE_PAIRS = 2 * (READ_PAIRS_EXAMINED - READ_PAIR_DUPLICATES)
        • READS_IN_UNIQUE_UNPAIRED = UNPAIRED_READS_EXAMINED - UNPAIRED_READ_DUPLICATES
        • READS_IN_DUPLICATE_PAIRS_OPTICAL = 2 * READ_PAIR_OPTICAL_DUPLICATES
        • READS_IN_DUPLICATE_PAIRS_NONOPTICAL = READS_IN_DUPLICATE_PAIRS - READS_IN_DUPLICATE_PAIRS_OPTICAL
        • READS_IN_DUPLICATE_UNPAIRED = UNPAIRED_READ_DUPLICATES
        • READS_UNMAPPED = UNMAPPED_READS
        loading..

        SamTools pre-sieve

        Samtools is a suite of programs for interacting with high-throughput sequencing data.DOI: 10.1093/bioinformatics/btp352.

        The pre-sieve statistics are quality metrics measured before applying (optional) minimum mapping quality, blacklist removal, mitochondrial read removal, read length filtering, and tn5 shift.

        Percent Mapped

        Alignment metrics from samtools stats; mapped vs. unmapped reads.

        For a set of samples that have come from the same multiplexed library, similar numbers of reads for each sample are expected. Large differences in numbers might indicate issues during the library preparation process. Whilst large differences in read numbers may be controlled for in downstream processings (e.g. read count normalisation), you may wish to consider whether the read depths achieved have fallen below recommended levels depending on the applications.

        Low alignment rates could indicate contamination of samples (e.g. adapter sequences), low sequencing quality or other artefacts. These can be further investigated in the sequence level QC (e.g. from FastQC).

        loading..

        Alignment metrics

        This module parses the output from samtools stats. All numbers in millions.

        loading..

        SamTools post-sieve

        Samtools is a suite of programs for interacting with high-throughput sequencing data.DOI: 10.1093/bioinformatics/btp352.

        The post-sieve statistics are quality metrics measured after applying (optional) minimum mapping quality, blacklist removal, mitochondrial read removal, and tn5 shift.

        Percent Mapped

        Alignment metrics from samtools stats; mapped vs. unmapped reads.

        For a set of samples that have come from the same multiplexed library, similar numbers of reads for each sample are expected. Large differences in numbers might indicate issues during the library preparation process. Whilst large differences in read numbers may be controlled for in downstream processings (e.g. read count normalisation), you may wish to consider whether the read depths achieved have fallen below recommended levels depending on the applications.

        Low alignment rates could indicate contamination of samples (e.g. adapter sequences), low sequencing quality or other artefacts. These can be further investigated in the sequence level QC (e.g. from FastQC).

        loading..

        Alignment metrics

        This module parses the output from samtools stats. All numbers in millions.

        loading..

        deepTools

        deepTools is a suite of tools to process and analyze deep sequencing data.DOI: 10.1093/nar/gkw257.

        PCA plot

        PCA plot with the top two principal components calculated based on genome-wide distribution of sequence reads

        loading..

        Fingerprint plot

        Signal fingerprint according to plotFingerprint

        loading..

        Read Distribution Profile after Annotation

        Accumulated view of the distribution of sequence reads related to the closest annotated gene. All annotated genes have been normalized to the same size.

        • Green: -3.0Kb upstream of gene to TSS
        • Yellow: TSS to TES
        • Pink: TES to 3.0Kb downstream of gene
        loading..

        macs2_frips

        Subread featureCounts is a highly efficient general-purpose read summarization program that counts mapped reads for genomic features such as genes, exons, promoter, gene bodies, genomic bins and chromosomal locations.DOI: 10.1093/bioinformatics/btt656.

        loading..

        deepTools - Spearman correlation heatmap of reads in bins across the genome

        Spearman correlation plot generated by deeptools. Spearman correlation is a non-parametric (distribution-free) method, and assesses the monotonicity of the relationship.


        deepTools - Pearson correlation heatmap of reads in bins across the genome

        Pearson correlation plot generated by deeptools. Pearson correlation is a parametric (lots of assumptions, e.g. normality and homoscedasticity) method, and assesses the linearity of the relationship.


        Peak distributions (macs2)

        The distribution of read pileup around 20000 random peaks for each sample. This visualization is a quick and dirty way to check if your peaks look like what you would expect, and what the underlying distribution of different types of peaks is.


        Peaks per sample distribution (macs2)

        The distribution of peaks between samples. An upset plot is like a venn diagram, but is easier to read with many samples. This figure shows the overlap of peaks between conditions/samples. .


        Peak feature distribution (macs2)

        Figure generated by chipseeker.


        Distribution of peak locations relative to TSS (macs2)

        Figure generated by chipseeker.


        DESeq2 - Sample distance cluster heatmap of counts

        Euclidean distance between samples, based on variance stabilizing transformed counts (RNA: expressed genes, ChIP: bound regions, ATAC: accessible regions). Gives us an overview of similarities and dissimilarities between samples.


        DESeq2 - Spearman correlation cluster heatmap of counts

        Correlation cluster heatmap based on variance stabilizing transformed counts. Spearman correlation is a non-parametric (distribution-free) method, and assesses the monotonicity of the relationship.


        DESeq2 - Pearson correlation cluster heatmap of counts

        Correlation cluster heatmap based on variance stabilizing transformed counts. Pearson correlation is a parametric (lots of assumptions, e.g. normality and homoscedasticity) method, and assesses the linearity of the relationship.


        gimme maelstrom macs2 results

        Gimme maelstrom is a method to infer differential motifs between samples. It solves a system of linear equations, Ax=b. Where we solve for x, A the motif scores and b the count table. It combines the results of different methods that solve this problem, and its result is the table below. It can be used to find **differential** motifs between samples.

         
        factors
        (direct or predicted)
        motif information z-score
        Brain
        z-score
        Testis
        z-score
        Skin
        z-score
        Muscle
        z-score
        Heart
        z-score
        Kidney
        z-score
        Spleen
        z-score
        Blood
        z-score
        Liver
        z-score
        Intestine
        z-score
        Colon
        %
        with
        motif
        corr
        Brain
        corr
        Testis
        corr
        Skin
        corr
        Muscle
        corr
        Heart
        corr
        Kidney
        corr
        Spleen
        corr
        Blood
        corr
        Liver
        corr
        Intestine
        corr
        Colon
        GM.5.0.C2H2_ZF.0281
        ZEB2A,NO ORTHOLOGS FOUND,ZEB2B,ZEB1B
        -1.49 2.61 2.57 -4.71 -1.45 2.85 -3.98 2.45 1.70 1.79 1.94
        <1
        -0.04 -0.01 0.03 -0.06 -0.02 0.07 -0.02 0.02 0.05 0.01 -0.01
        GM.5.0.RFX.0016
        RFX1B,RFX3,RFX2,RFX1A
        1.57 0.92 0.32 -0.02 0.15 -3.26 -0.97 -0.55 1.66 -0.95 -0.89
        <1
        0.05 -0.01 -0.00 0.00 -0.03 -0.02 0.01 -0.00 0.05 -0.03 -0.04
        GM.5.0.bHLH.0086
        OLIG2,OLIG3,OLIG1,BHLHE23
        0.74 1.98 1.07 -0.54 0.82 -1.20 0.77 -1.36 -3.36 0.81 0.87
        <1
        0.00 0.02 0.01 -0.02 0.00 -0.01 -0.01 -0.00 -0.01 0.02 -0.00
        GM.5.0.CxxC.0001
        CXXC1A,CXXC1B
        -0.95 2.04 -2.77 -1.71 -1.59 -0.05 -0.33 3.92 2.18 -1.52 -2.31
        <1
        0.00 0.03 -0.04 -0.03 -0.07 0.01 0.01 0.06 0.09 -0.04 -0.06
        GM.5.0.SMAD.0013
        SMAD9,SMAD1,SMAD5
        -0.15 4.17 2.33 -3.60 -1.84 0.56 1.12 2.83 0.58 -2.67 -2.22
        <1
        0.05 0.06 -0.02 -0.04 -0.07 0.01 0.02 0.06 0.06 -0.09 -0.08
        GM.5.0.bHLH.0079
        MYCB,MYCA
        0.13 3.61 -1.36 -0.61 -2.30 -0.14 -0.24 3.71 -0.42 -0.33 -1.78
        <1
        0.03 0.06 -0.04 -0.04 -0.09 0.02 0.01 0.07 0.06 -0.05 -0.07
        GM.5.0.Homeodomain.0136
        NO ORTHOLOGS FOUND,PBX4,PBX1A,PBX3B,PBX1B, (...)
        -3.97 0.88 1.19 -2.10 -1.12 1.16 2.31 0.21 1.71 -1.05 0.48
        2
        -0.06 -0.03 -0.00 -0.04 -0.01 0.04 0.03 0.01 0.09 0.00 -0.02
        GM.5.0.C2H2_ZF.0057
        KLF5B,KLF17,SP8A,KLF5A,KLF2A, (...)
        -3.38 4.28 3.84 2.34 0.08 0.83 -1.23 -4.02 -3.43 2.34 1.06
        <1
        -0.01 0.02 0.06 0.02 0.02 -0.01 0.00 -0.06 -0.07 0.03 0.03
        GM.5.0.Mixed.0015
        TAF1,TCF3B,TCF12,TCF4,GABPA, (...)
        0.29 0.58 1.18 -0.38 -1.84 0.44 1.25 3.16 1.82 -2.29 -1.57
        <1
        -0.02 0.01 -0.02 -0.01 -0.09 0.05 0.04 0.06 0.10 -0.06 -0.07
        GM.5.0.T-box.0008
        TBX5A,EOMESB,TBX4,TBX1,NO ORTHOLOGS FOUND, (...)
        -0.23 0.63 2.69 -3.01 0.77 -0.59 -3.40 -1.33 -1.63 3.13 4.00
        <1
        -0.02 -0.03 0.05 -0.04 0.02 0.02 -0.03 -0.03 -0.01 0.05 0.04
        GM.5.0.C2H2_ZF.0169
        LOC100333406,LOC101883139,GLIS3,GLIS2B,GLIS2A, (...)
        1.80 -2.24 -1.77 -1.09 -0.83 -1.66 2.04 0.41 1.48 0.71 3.34
        <1
        0.04 -0.05 -0.00 0.01 -0.00 0.01 0.02 -0.00 0.01 -0.04 -0.02
        GM.5.0.Mixed.0020
        BATF,MYT1LA,MYT1A,IRF4B,IRF8, (...)
        -3.54 -0.11 2.59 2.39 -0.94 2.73 2.82 1.46 1.76 -0.44 0.15
        <1
        -0.05 -0.04 -0.01 0.00 -0.05 0.07 0.05 0.02 0.08 -0.04 -0.04
        GM.5.0.Unknown.0047
        CDX4,LOC101886517,CDX1A,CDX1B
        -0.76 1.04 0.42 0.95 0.86 0.00 -0.03 0.67 -0.56 1.48 3.69
        <1
        -0.02 0.01 0.00 -0.01 -0.00 -0.01 -0.02 0.00 0.00 0.03 0.02
        GM.5.0.T-box.0019
        EOMESB,TBX21,TBR1B,EOMESA,TBR1A, (...)
        -0.78 2.58 3.70 -4.53 1.37 0.58 -2.81 0.38 -1.12 2.78 3.22
        1
        -0.04 0.02 0.04 -0.04 -0.01 0.01 -0.03 0.01 0.02 0.02 0.01
        GM.5.0.bZIP.0075
        SI_CH211-153J24.3,FOSAB,FOSAA
        1.80 -1.75 0.31 1.85 1.55 0.60 0.24 -3.23 -1.85 0.99 0.39
        2
        0.09 -0.07 0.01 0.03 0.05 -0.03 0.01 -0.07 -0.05 0.00 0.00
        GM.5.0.E2F.0013
        E2F1,E2F8,E2F7
        1.68 1.58 -2.28 -0.25 -2.38 -0.94 1.13 3.38 0.45 -2.22 -2.21
        <1
        0.09 -0.01 -0.05 0.02 -0.06 0.00 0.04 0.05 0.05 -0.10 -0.09
        GM.5.0.bHLH.0019
        NO ORTHOLOGS FOUND
        -1.07 -1.46 -0.98 -1.12 3.20 -0.21 1.77 -3.83 0.28 1.23 1.23
        1
        0.05 -0.08 -0.02 0.02 0.05 -0.01 0.02 -0.06 0.02 -0.00 -0.01
        GM.5.0.C2H2_ZF.0152
        PLAG1,NO ORTHOLOGS FOUND,PLAGL2
        0.54 -2.05 -1.40 3.03 1.81 0.24 0.16 0.13 0.31 1.73 1.28
        1
        0.03 -0.09 -0.02 0.03 0.03 0.02 0.01 -0.03 0.02 -0.01 -0.01
        GM.5.0.GCM.0004
        MYRFL,MYRF,GCM2
        1.53 -0.37 -0.69 -2.52 0.88 -0.82 -3.16 -0.41 -0.81 0.16 -0.25
        <1
        0.04 -0.01 0.01 -0.04 0.01 -0.02 -0.03 0.01 0.00 0.01 0.00
        GM.5.0.Homeodomain.0038
        NKX3-1,NKX2.7,NKX2.5,NKX2.3,TLX3B, (...)
        -0.26 2.75 0.80 1.18 0.71 0.51 0.74 1.66 -3.89 0.18 1.20
        <1
        -0.01 -0.01 0.01 -0.01 -0.02 0.05 0.01 0.00 -0.00 -0.00 -0.01
        GM.5.0.SAND.0005
        NO ORTHOLOGS FOUND,ARHGEF12B,ARHGEF12A
        -1.18 2.87 1.09 -0.76 -3.51 0.00 1.20 3.83 2.63 -2.83 -4.57
        <1
        0.00 0.03 -0.04 0.00 -0.10 0.04 0.05 0.08 0.09 -0.09 -0.10
        GM.5.0.Homeodomain.0041
        POU3F2B,POU3F2A,HOXB9A,HOXA10B,HOXB6B, (...)
        0.55 1.55 -1.07 0.78 -1.70 -2.66 0.13 2.27 -3.60 -1.61 1.34
        <1
        0.07 -0.01 -0.01 -0.01 -0.06 0.02 -0.01 0.03 0.01 -0.03 -0.02
        GM.5.0.Homeodomain.0017
        PBX4,PBX1A,PBX3B,PBX1B,PBX3A, (...)
        -0.02 -0.03 3.04 -0.46 1.47 -0.46 0.61 -1.52 -2.40 0.16 1.43
        1
        0.07 -0.02 0.02 -0.03 -0.01 0.01 -0.02 -0.02 -0.01 -0.00 -0.01
        GM.5.0.Homeodomain.0085
        NO ORTHOLOGS FOUND,SIX1B,SIX1A,SIX2B,SIX2A
        -2.01 -1.68 3.03 0.70 -1.24 1.00 1.50 0.80 2.00 0.20 -0.41
        1
        -0.01 -0.04 0.00 0.01 -0.04 0.04 0.03 -0.00 0.07 -0.04 -0.04
        GM.5.0.C2H2_ZF.0317
        FEZF2,FEZF1
        0.74 0.05 -3.61 1.40 -1.05 0.15 0.80 -0.85 0.24 -0.02 -0.46
        <1
        0.08 -0.06 -0.05 0.03 -0.03 0.01 0.04 -0.01 0.05 -0.05 -0.05
        GM.5.0.C2H2_ZF.0019
        SP4,SP8A,SP8B,KLF7A,SP9, (...)
        -3.89 1.63 4.48 1.13 -3.00 3.09 3.06 1.77 -2.13 -2.03 -2.48
        <1
        -0.01 0.01 0.06 -0.01 -0.04 0.03 0.02 0.01 -0.01 -0.03 -0.04
        GM.5.0.bZIP.0073
        CREBZF
        -1.17 3.17 0.21 -2.72 -2.97 1.73 0.29 3.35 2.58 0.09 -2.27
        <1
        -0.03 0.03 -0.02 -0.05 -0.08 0.06 0.01 0.06 0.08 -0.03 -0.05
        GM.5.0.CUT_Homeodomain.0006
        CUX1B,CUX1A,CUX2B
        0.07 -1.12 0.35 0.53 -0.65 -3.08 -2.20 -0.79 -0.44 1.41 0.79
        <1
        0.02 -0.00 0.01 0.01 -0.00 -0.03 -0.03 -0.01 0.01 0.01 0.01
        GM.5.0.Homeodomain.0054
        NKX2.7,NKX2.5,NKX2.3,NKX2.1,NKX2.4A, (...)
        -0.68 -0.34 -0.32 -0.57 4.02 -0.50 3.02 0.45 -1.27 0.46 0.56
        <1
        -0.01 -0.04 -0.02 -0.00 0.05 0.01 0.06 -0.01 -0.02 -0.01 -0.01
        GM.5.0.C2H2_ZF.0113
        NO ORTHOLOGS FOUND
        -0.76 -1.83 -0.27 1.91 3.89 -1.78 1.71 0.22 -2.29 -1.26 -0.78
        <1
        0.07 -0.02 -0.04 0.00 -0.01 -0.00 0.02 0.04 0.03 -0.07 -0.06
        GM.5.0.C2H2_ZF.0068
        GFI1B,GFI1AA,GFI1AB,NO ORTHOLOGS FOUND
        2.30 1.06 0.83 0.91 0.19 -0.47 -3.88 -3.69 2.28 0.70 1.81
        1
        0.07 -0.01 -0.01 0.00 -0.02 0.00 -0.04 -0.04 0.05 -0.03 -0.03
        GM.5.0.Homeodomain.0177
        NKX3-1,NKX2.7,NKX2.5,NKX2.3,NKX2.9, (...)
        -0.78 0.65 -0.85 0.50 2.51 -0.03 3.73 0.38 -0.99 0.02 -0.74
        <1
        -0.02 -0.02 -0.01 -0.01 0.02 0.03 0.05 0.01 0.00 -0.01 -0.02
        GM.5.0.GATA.0016
        GATA1A,GATA1B,GATA2A,GATA3
        -1.08 0.82 2.26 -2.28 0.27 -2.97 -3.01 -1.66 1.80 2.44 1.93
        2
        0.00 -0.03 -0.01 -0.02 0.01 -0.02 -0.01 -0.01 0.05 0.02 -0.01
        GM.5.0.IRF.0006
        IRF7,IRF1B,IRF2,STAT1B,IRF3, (...)
        -1.89 -2.11 1.40 -0.43 -2.52 1.79 3.48 0.77 2.46 -1.23 -0.83
        <1
        0.10 -0.09 -0.03 0.07 -0.04 0.00 0.11 -0.01 0.01 -0.10 -0.08
        GM.5.0.C2H2_ZF.0275
        NKX3.3,NKX3.2,NKX2.7,NKX2.5,NKX2.3, (...)
        -1.16 -1.90 -2.60 0.07 1.68 -0.34 3.21 -2.40 -0.94 1.23 2.34
        2
        -0.00 -0.05 -0.01 0.02 0.03 0.01 0.07 -0.05 -0.03 0.02 0.01
        GM.5.0.THAP_finger.0005
        THAP1,THAP3
        1.10 3.58 -1.78 -2.40 -0.54 -0.97 2.57 4.55 1.72 -3.63 -1.69
        <1
        0.07 0.03 -0.05 -0.03 -0.04 0.00 0.02 0.05 0.05 -0.08 -0.07
        GM.5.0.C2H2_ZF.0105
        ZBTB7A,INSM1A,ZBTB7C,ZIC1,INSM1B, (...)
        -0.12 -2.76 -3.61 2.93 1.51 -1.67 2.87 2.03 1.54 -2.90 -2.83
        <1
        0.02 -0.07 -0.03 0.04 0.01 0.02 0.04 0.01 0.06 -0.05 -0.05
        GM.5.0.T-box.0013
        TBX2A,TBX2B,ZEB1B,TBX3A,ZEB2B, (...)
        1.06 -2.24 3.80 -3.33 1.75 0.85 -3.50 0.17 -2.28 2.68 3.87
        2
        0.02 -0.06 0.06 -0.04 0.03 0.01 -0.03 -0.02 -0.01 0.02 0.02
        GM.5.0.C2H2_ZF.0171
        SP9,NO ORTHOLOGS FOUND,TERFA,SP3A
        0.14 0.57 1.70 -2.07 0.32 -1.52 -1.34 -0.07 -1.04 3.25 2.76
        1
        -0.02 -0.02 0.01 -0.03 0.00 0.02 -0.02 -0.00 0.03 0.03 0.01
        GM.5.0.ARID_BRIGHT.0001
        ARID3B,ARID3A,CUX1B,ARID3C,CUX1A
        3.81 1.67 0.23 -2.29 2.14 -0.92 -2.64 2.92 -1.30 -3.24 -1.43
        <1
        0.09 -0.01 -0.03 -0.05 -0.04 0.01 -0.02 0.04 0.04 -0.04 -0.03
        GM.5.0.bHLH.0054
        TCF3B,NO ORTHOLOGS FOUND,TCF7L2,TCF12,TCF4, (...)
        1.09 -3.36 -0.22 2.26 3.91 -0.96 -3.05 -2.02 0.58 -0.90 -0.75
        1
        0.05 -0.08 0.02 0.03 0.05 0.01 -0.01 -0.03 0.00 -0.03 -0.03
        GM.5.0.Homeodomain.0168
        NKX2.5,PRDM1A,NKX2.3,NKX2.7
        0.54 -2.80 -1.14 0.34 2.69 -0.01 3.53 2.02 -0.33 -1.30 -0.72
        1
        0.02 -0.08 -0.02 0.02 0.00 0.03 0.10 -0.00 0.01 -0.05 -0.05
        GM.5.0.Mixed.0043
        HINFP
        -2.56 4.70 -2.19 -0.55 -1.46 1.23 1.49 3.26 0.85 0.39 -1.02
        <1
        0.00 0.05 -0.05 -0.02 -0.07 0.02 0.03 0.06 0.06 -0.05 -0.06
        GM.5.0.C2H2_ZF.0168
        SI_DKEY-17E16.13,OVOL1,ZGC_171929
        -2.01 2.17 0.86 -1.62 -0.71 -0.01 -3.77 -1.49 0.24 1.73 2.72
        2
        -0.03 -0.00 -0.00 -0.02 -0.02 0.04 -0.01 -0.01 0.04 0.01 -0.00
        GM.5.0.C2H2_ZF.0226
        SP8B,TCF3B,SP2,ZBTB7A,TCF12, (...)
        3.31 1.14 -1.19 -0.02 -2.90 -0.50 1.34 1.70 0.97 -1.18 -1.81
        1
        0.09 0.00 -0.04 -0.00 -0.07 0.00 0.06 0.04 0.03 -0.07 -0.08
        GM.5.0.C2H2_ZF.0293
        NO ORTHOLOGS FOUND
        3.06 -3.23 -1.25 -0.77 -1.21 -1.26 0.12 0.43 -0.57 -0.37 -2.04
        <1
        0.12 -0.10 -0.02 0.03 -0.01 0.01 0.05 -0.02 0.01 -0.06 -0.06
        GM.5.0.Unknown.0141
        ITGB2
        1.59 -0.64 -2.19 3.12 3.02 -1.81 1.19 -2.02 -1.38 -2.05 -1.86
        2
        0.03 -0.07 -0.03 0.04 0.04 0.01 0.01 -0.04 0.03 -0.02 -0.03
        GM.5.0.C2H2_ZF.0094
        NO ORTHOLOGS FOUND
        -0.28 -2.25 1.50 -0.13 -0.52 1.00 -2.18 -3.59 0.79 4.32 2.75
        2
        -0.02 -0.03 0.01 -0.00 0.02 -0.01 -0.03 -0.05 0.02 0.07 0.04
        GM.5.0.bZIP.0093
        YY1A,NO ORTHOLOGS FOUND,YY1B,EF1,NFE2, (...)
        -0.75 3.49 -1.34 -2.55 0.03 3.08 -0.30 1.44 1.05 -1.51 -2.20
        <1
        0.06 0.05 -0.04 -0.03 -0.07 0.04 0.03 0.07 0.06 -0.11 -0.10
        GM.5.0.C2H2_ZF.0166
        SP8A,SP8B,SP9,SP2,SP3A, (...)
        -1.66 1.42 0.81 -0.12 -0.88 2.90 2.60 -0.62 -0.15 -3.88 -2.93
        <1
        0.11 -0.01 -0.01 0.01 -0.02 0.01 0.06 0.00 -0.00 -0.11 -0.09
        GM.5.0.C2H2_ZF.0283
        RAD21A,RAD21B,CTCF
        -2.85 -0.38 -0.72 -2.86 -1.76 4.13 0.04 0.90 2.50 0.86 -1.07
        1
        -0.05 -0.01 -0.02 -0.04 -0.03 0.08 -0.00 0.02 0.09 -0.01 -0.02
        GM.5.0.Homeodomain.0097
        OTPB,OTPA,DRGX,PROP1,ALX1, (...)
        3.03 -0.38 -2.56 0.84 -0.70 -2.13 0.31 0.06 -0.15 0.98 -1.42
        <1
        0.08 -0.02 -0.03 -0.02 -0.03 -0.00 0.00 0.02 0.02 -0.03 -0.04
        GM.5.0.p53.0006
        TP53,TP63,TP73
        -0.28 -0.81 3.82 -1.80 0.57 -0.48 -1.63 -1.08 -0.31 1.56 1.00
        1
        0.01 -0.08 0.04 -0.01 0.01 0.03 0.00 -0.02 0.04 -0.01 -0.02
        GM.5.0.IRF.0008
        IRF6,IRF5,IRF4B,IRF8,IRF3, (...)
        -2.43 2.04 -1.92 -0.08 0.14 2.54 2.96 0.51 1.04 -2.10 -3.03
        <1
        0.04 -0.04 -0.04 0.06 -0.05 0.03 0.09 0.02 0.05 -0.10 -0.09
        GM.5.0.C2H2_ZF.0031
        PBX4,PBX1A,PBX3B,PBX3A,PBX1B, (...)
        0.62 1.55 -0.47 -0.13 0.64 0.45 0.33 1.40 0.23 -2.94 -3.91
        1
        0.06 -0.00 -0.01 -0.00 0.00 0.00 0.01 0.00 0.02 -0.06 -0.06
        GM.5.0.bZIP.0023
        MAFAA,MAFBA,MAFB,MAFA,REST, (...)
        1.67 -0.43 -3.41 1.10 0.09 -0.30 3.38 -0.17 2.34 -3.14 -2.05
        <1
        0.07 -0.03 -0.04 0.00 -0.01 -0.00 0.03 -0.00 0.06 -0.05 -0.06
        GM.5.0.Forkhead.0058
        FOXD1,FOXF1,FOXL2,AP5Z1,FOXA2, (...)
        -2.01 1.84 -3.68 1.40 0.94 -0.33 0.12 -2.33 1.40 -0.05 1.25
        2
        -0.04 0.00 -0.03 0.03 0.03 0.00 -0.00 -0.05 0.02 0.03 0.02
        GM.5.0.bZIP.0081
        TEFB,HLFB,HLFA,TEFA
        0.31 -1.19 0.33 0.66 3.15 -0.00 -0.44 -1.28 0.98 1.40 0.15
        2
        -0.01 0.00 -0.00 -0.03 -0.01 -0.00 -0.02 -0.01 0.06 0.01 -0.00
        GM.5.0.bZIP.0080
        E2F3,SI_CH211-160F23.5,LOC101882957,LOC101882221,E2F4, (...)
        2.46 4.04 -2.63 -2.54 -4.28 -1.88 1.41 4.70 1.11 -2.51 -2.64
        2
        0.06 0.07 -0.04 -0.04 -0.09 -0.01 0.02 0.08 0.05 -0.07 -0.08
        GM.5.0.p53.0004
        TP73,TP63,TP53,MDM4,MDM2, (...)
        -3.43 -1.05 5.62 -0.78 -2.52 -0.78 -0.33 -0.52 -0.23 -0.14 -0.49
        1
        -0.04 -0.03 0.10 -0.03 -0.01 0.01 -0.01 -0.01 0.02 0.01 0.00
        GM.5.0.Ets.0035
        ETS1,ZBTB33,CHD2,NR3C1,CHD1, (...)
        0.01 3.82 -2.86 -0.44 -2.62 1.02 1.24 3.16 3.00 -3.24 -3.10
        <1
        0.05 0.04 -0.05 0.00 -0.09 0.01 0.03 0.07 0.09 -0.10 -0.09
        GM.5.0.E2F.0009
        ZBTB14,NO ORTHOLOGS FOUND,E2F3,E2F1,SI_CH211-160F23.5
        2.30 5.64 -2.51 -0.68 -3.74 -1.59 0.04 2.15 -1.36 -2.31 -2.85
        1
        0.09 0.11 -0.05 -0.03 -0.09 -0.01 0.02 0.08 0.02 -0.09 -0.09
        GM.5.0.SMAD.0005
        SMAD3B,SMAD3A,SMAD2,SI_DKEY-239N17.4,GB_CR929477, (...)
        3.38 -1.59 0.97 0.13 0.48 -3.25 1.38 -1.14 -0.12 -0.60 -0.94
        2
        0.11 -0.08 0.01 0.03 0.05 -0.05 0.02 -0.05 -0.04 -0.01 -0.01
        GM.5.0.Homeodomain.0155
        HMG20B,SOX21B,CUX1B,CUX1A,MEOX2B, (...)
        1.71 2.47 -0.02 -2.43 -1.30 -3.47 1.88 0.58 -2.69 0.93 1.75
        1
        0.07 0.02 -0.01 -0.05 -0.03 -0.01 -0.01 0.02 -0.01 -0.01 -0.01
        GM.5.0.Homeodomain.0133
        HOXA9B,HOXC9A,HOXB9A,HOXA9A,HOXD9A, (...)
        -0.64 -2.36 -0.94 0.21 -1.74 1.70 -1.64 0.18 0.32 3.05 4.66
        <1
        0.03 -0.02 -0.02 -0.03 -0.05 0.04 -0.03 0.01 0.03 0.02 0.01
        GM.5.0.C2H2_ZF.0088
        NO ORTHOLOGS FOUND
        3.19 -1.26 0.50 -0.28 2.75 -2.74 -0.76 -3.32 -3.42 -0.34 -3.17
        2
        0.09 -0.06 -0.02 0.02 0.02 -0.01 0.02 -0.02 0.00 -0.04 -0.04
        GM.5.0.Unknown.0017
        NO ORTHOLOGS FOUND
        -2.17 0.15 2.39 2.00 3.18 1.11 -1.24 -2.01 0.17 0.40 0.77
        1
        -0.02 -0.04 0.02 0.02 0.02 0.01 -0.00 -0.03 0.03 -0.00 -0.01
        GM.5.0.Homeodomain.0198
        HOXA9B,HOXC9A,HOXB9A,HOXA9A,HOXB6A, (...)
        -2.11 1.21 2.44 -0.85 -2.00 1.50 -0.86 -1.35 -1.94 4.70 3.78
        1
        0.02 -0.01 0.01 -0.02 -0.04 0.03 -0.03 -0.00 0.00 0.02 0.01
        GM.5.0.Ets.0036
        KLF13,ZGC_153115,SI_DKEY-17E16.13,OVOL1,MYBL2B, (...)
        1.59 1.30 -3.14 0.77 0.52 0.69 0.24 0.92 -0.01 -2.10 -2.25
        1
        0.04 -0.00 -0.06 0.02 -0.05 0.02 0.05 0.04 0.06 -0.08 -0.08
        GM.5.0.Homeodomain.0010
        DHARMA,IRX3A,PHOX2BA,IRX6A,IRX4B, (...)
        -0.83 0.16 -0.37 0.17 0.30 -0.32 0.60 -2.37 -2.21 1.38 3.54
        <1
        0.00 -0.02 -0.02 -0.01 -0.01 0.01 0.00 -0.02 0.03 0.02 0.00
        GM.5.0.Myb_SANT.0013
        SMARCA5,NO ORTHOLOGS FOUND,SMARCA1
        2.14 0.36 2.13 2.37 0.01 0.76 0.42 0.06 -3.98 -2.40 -0.34
        1
        0.10 -0.08 -0.01 0.08 -0.02 0.01 0.07 -0.01 -0.03 -0.08 -0.07
        GM.5.0.Nuclear_receptor.0036
        NR2F1A,NR2F5,NR2F1B,NR2F2,RARAB, (...)
        -4.21 1.27 -2.82 -1.59 -1.69 3.74 0.49 0.71 3.23 0.75 1.16
        1
        -0.11 -0.05 -0.06 -0.03 -0.02 0.11 0.01 -0.02 0.15 0.02 0.00
        GM.5.0.C2H2_ZF.0239
        SI_DKEY-166N8.9,IKZF1,SI_ZFOS-1425H8.1
        -2.77 1.34 1.62 3.13 1.53 2.46 -0.05 -1.75 0.73 -0.47 -1.22
        <1
        -0.00 -0.04 0.01 0.05 0.00 0.04 0.02 -0.02 0.02 -0.05 -0.05
        GM.5.0.E2F.0018
        E2F4,E2F5,SI_CH211-195D17.2,LIN54,E2F1
        1.55 2.09 -2.57 0.66 0.96 -1.00 2.37 2.97 1.73 -3.85 -3.38
        <1
        0.04 0.01 -0.04 -0.00 -0.02 0.00 0.04 0.05 0.06 -0.09 -0.08
        GM.5.0.C2H2_ZF.0010
        TCF3B,TCF12,TCF4,ZEB1B,SNAI2, (...)
        -1.78 1.68 3.99 -4.56 -1.19 3.10 -4.27 -0.75 2.58 2.47 1.96
        1
        -0.03 -0.03 0.03 -0.03 -0.03 0.05 -0.03 -0.01 0.09 0.00 -0.01
        GM.5.0.Grainyhead.0004
        GRHL2B,GRHL1,GRHL3,GRHL2A,TFCP2, (...)
        -1.78 0.29 3.44 -2.51 -1.63 4.25 -2.71 0.65 3.32 -0.34 -1.08
        1
        -0.05 -0.03 0.03 -0.03 -0.07 0.07 -0.00 0.02 0.12 -0.03 -0.04
        GM.5.0.GATA.0025
        GATA1A,GATA2A,GATA1B,GATA3,ESR1, (...)
        -1.03 0.28 2.10 -2.52 -0.89 3.03 -1.35 1.10 1.13 1.89 1.53
        1
        -0.02 -0.03 0.00 -0.02 -0.02 0.06 -0.00 -0.01 0.06 -0.01 -0.02
        GM.5.0.Nuclear_receptor.0104
        RXRAB,ZBTB7A,RXRAA,RXRGA,RXRBA, (...)
        3.17 2.20 -2.63 -2.11 -2.61 1.10 0.70 1.52 2.61 -1.64 -3.44
        2
        0.12 0.02 -0.06 -0.01 -0.05 -0.02 0.04 0.03 0.02 -0.08 -0.07
        GM.5.0.Unknown.0050
        NO ORTHOLOGS FOUND
        -1.16 0.32 -0.90 2.15 -1.50 0.95 4.37 0.13 -2.30 0.40 0.31
        2
        0.05 -0.06 -0.03 0.07 -0.03 -0.00 0.08 -0.02 -0.00 -0.04 -0.04
        GM.5.0.Nuclear_receptor.0045
        ESR2B,ESR1,ESR2A,NR2F1B,NR2F2, (...)
        -5.03 2.05 -4.08 2.12 2.54 3.26 4.13 -1.49 2.82 -1.38 0.45
        <1
        -0.14 -0.05 -0.08 -0.02 0.01 0.11 0.02 -0.03 0.18 0.02 -0.00
        GM.5.0.E2F.0006
        E2F1,TFDP1B,E2F5,TFDP1A,E2F4, (...)
        1.92 2.74 -4.07 1.61 -3.28 -0.63 1.68 1.25 0.25 -3.59 -3.05
        <1
        0.14 -0.02 -0.04 0.04 -0.04 -0.01 0.07 0.00 -0.01 -0.10 -0.08
        GM.5.0.Homeodomain.0185
        HNF1A,ZGC_91944,HMBOX1A,HNF1BA,HMBOX1B
        -2.62 -0.88 0.28 -2.59 -1.36 4.74 1.19 0.25 1.75 0.41 -0.76
        <1
        -0.07 -0.02 -0.04 -0.07 -0.06 0.14 0.00 0.03 0.11 -0.01 -0.03
        GM.5.0.Homeodomain.0009
        HOXA9B,HOXC9A,HOXB9A,HOXA9A,HOXD9A, (...)
        -1.87 0.79 -0.40 -0.03 -3.44 -1.19 -2.09 0.01 -2.26 5.02 5.18
        1
        0.03 -0.00 -0.03 -0.02 -0.06 0.02 -0.00 0.02 0.02 0.00 0.00
        GM.5.0.Sox.0034
        SOX9A,SOX9B,SOX10,SOX4A,SOX2, (...)
        -0.47 -2.88 -1.78 3.86 -0.01 1.38 -1.22 -2.50 -0.44 -1.22 -1.93
        <1
        0.04 -0.07 -0.01 0.06 -0.02 0.01 -0.02 -0.03 0.06 -0.03 -0.04
        GM.5.0.bHLH.0047
        HEYL,HEY1,HER9,HER2,ATF3, (...)
        1.21 3.09 -0.75 -2.97 0.26 -0.54 0.35 1.55 -1.46 -1.49 -1.20
        1
        0.04 0.03 -0.01 -0.04 -0.03 0.01 0.00 0.04 0.04 -0.06 -0.06
        GM.5.0.Sox.0033
        HBP1,SOX2,SOX8A,NO ORTHOLOGS FOUND,SOX1B, (...)
        4.86 -0.22 -0.05 1.18 -2.14 -1.90 -1.27 -2.10 -0.26 -1.01 -2.39
        <1
        0.11 -0.02 -0.00 0.00 -0.04 0.01 -0.02 -0.01 0.00 -0.04 -0.04
        GM.5.0.Forkhead.0007
        FOXO3B,FOXO4,SI_CH211-206A7.2,FOXO3A,FOXD1, (...)
        -0.93 -2.10 -1.20 -0.80 -1.23 -2.77 -1.34 -0.22 3.42 3.35 -0.28
        <1
        -0.04 -0.01 -0.04 -0.01 -0.04 -0.01 -0.02 -0.01 0.14 0.02 -0.01
        GM.5.0.Unknown.0007
        NRF1,ZBTB14,EGR1,SETDB1B,SI_CH211-195D17.2, (...)
        0.04 -0.77 -2.08 -1.38 -3.05 1.21 2.21 2.81 1.50 -0.17 -2.46
        1
        0.02 0.03 -0.01 -0.02 -0.06 -0.01 0.00 0.02 0.01 -0.00 -0.02
        GM.5.0.Nuclear_receptor.0017
        VDRA,NR1I2,VDRB,RXRAB,RXRAA, (...)
        -3.23 0.10 0.28 0.45 0.70 1.74 1.18 1.06 2.47 -0.44 -0.45
        1
        -0.09 -0.04 -0.03 -0.02 -0.01 0.08 0.01 -0.01 0.11 0.01 -0.01
        GM.5.0.C2H2_ZF.0020
        EGR1,EGR2B,WT1B,WT1A,NO ORTHOLOGS FOUND, (...)
        2.90 -0.26 -0.57 3.15 -1.54 -1.40 1.55 -1.51 -0.08 1.05 0.80
        1
        0.02 0.03 0.02 0.02 -0.01 -0.03 0.00 -0.03 -0.06 0.02 0.02
        GM.5.0.bHLH.0132
        EBF1A,EBF3A,EBF1B,EBF2,SI_CH211-263K4.2
        -1.02 0.10 0.10 4.70 0.10 1.07 -1.79 -0.10 -2.19 1.45 2.43
        1
        0.01 -0.07 -0.01 0.06 -0.00 0.05 0.02 -0.02 0.02 -0.03 -0.03
        GM.5.0.Mixed.0035
        TAL1,ZBTB7A,NO ORTHOLOGS FOUND
        3.66 -1.18 0.24 -0.47 -0.82 -3.41 -0.51 -0.21 -2.98 1.76 2.01
        3
        0.13 -0.09 -0.04 0.03 0.02 -0.06 0.05 -0.02 -0.02 -0.02 -0.03
        GM.5.0.Pipsqueak.0001
        LCOR,CDX4,CDX1A,CDX1B,LOC101886517
        1.34 -3.52 -3.03 2.34 0.39 -2.39 3.04 4.27 3.61 -4.25 -3.72
        <1
        0.04 -0.05 -0.03 0.03 -0.02 -0.01 0.03 0.04 0.10 -0.10 -0.09
        GM.5.0.Sox.0002
        SOX17,SOX18,SOX6,SOX5,SOX9A, (...)
        -0.53 -1.16 1.68 5.42 -0.07 0.41 -3.59 -3.33 -3.30 -1.17 -1.21
        2
        0.02 -0.03 -0.01 0.07 -0.03 0.01 -0.03 -0.02 0.07 -0.04 -0.05
        GM.5.0.Unknown.0180
        NO ORTHOLOGS FOUND
        1.95 -1.52 0.18 0.15 3.32 0.27 -0.17 0.40 -0.67 -1.21 0.73
        1
        0.14 -0.08 -0.01 0.03 0.03 -0.01 0.03 -0.04 -0.05 -0.05 -0.03
        GM.5.0.Nuclear_receptor.0005
        NR1H4,NR4A2B,NR4A1,RXRAB,RXRAA, (...)
        -3.88 -0.77 -1.70 -1.73 -1.87 1.14 1.65 -0.11 4.60 1.63 1.05
        1
        -0.10 -0.05 -0.05 -0.04 -0.02 0.08 0.01 -0.01 0.16 0.02 -0.00
        GM.5.0.THAP_finger.0002
        HIC1,HIC2,THAP1,THAP3
        3.75 -2.94 2.71 -2.21 2.57 0.91 -4.00 -0.06 0.56 -2.32 -2.03
        <1
        0.11 -0.10 -0.00 -0.00 0.02 0.03 -0.01 -0.01 0.05 -0.07 -0.06
        GM.5.0.Homeodomain.0157
        POU3F2B,LHX1A,ARID3C,POU5F3,LOC100008066, (...)
        3.19 -0.37 0.56 -3.12 -1.75 0.28 -2.75 2.98 -0.68 -1.85 -2.50
        <1
        0.08 -0.01 -0.03 -0.04 -0.05 0.06 -0.02 0.03 0.03 -0.05 -0.05
        GM.5.0.bHLH.0009
        MAX,USF2,MYCB,MYCA,ARNTL1B, (...)
        -2.49 -0.92 -0.33 -3.18 0.24 2.88 -0.78 -1.06 1.97 -0.66 0.77
        1
        -0.03 -0.01 0.01 -0.03 -0.01 0.04 -0.00 -0.00 0.05 -0.01 -0.01
        GM.5.0.GATA.0031
        NO ORTHOLOGS FOUND,SMAD3B,GATA1A,GATA2A,GATA1B, (...)
        2.53 -1.14 0.73 2.53 3.34 -4.10 -0.30 -2.15 -2.62 -0.83 -0.36
        2
        0.10 -0.07 0.00 0.04 0.05 -0.05 0.00 -0.05 -0.03 -0.02 -0.01
        GM.5.0.Forkhead.0034
        FOXA2,FOXA3,FOXA1,FOXD1,FOXF1, (...)
        -0.45 -1.14 -2.64 0.60 0.33 -1.94 -0.14 -2.09 4.13 -0.68 -3.76
        <1
        0.01 -0.02 -0.03 0.02 -0.04 -0.02 -0.01 -0.01 0.12 -0.03 -0.04
        GM.5.0.bZIP.0086
        MAFAA,NO ORTHOLOGS FOUND,MAFBA,MAFB,MAFA
        -2.55 -1.95 0.49 3.18 1.66 0.56 3.74 -2.26 -0.57 -1.09 0.24
        2
        0.03 -0.08 -0.01 0.06 0.00 0.03 0.10 -0.02 -0.01 -0.06 -0.05
        GM.5.0.Mixed.0005
        OTX2,CRX,OTX1A,OTX5,PITX3, (...)
        3.56 -3.13 -1.10 -1.15 2.03 -1.77 -2.45 2.27 -1.92 0.98 0.94
        <1
        0.10 -0.03 -0.03 -0.04 -0.02 0.02 -0.03 0.02 0.01 -0.03 -0.04
        GM.5.0.CUT_Homeodomain.0005
        CUX2B,CUX1B,CUX1A,ONECUT3A,ONECUT1, (...)
        -2.38 0.27 -2.10 -2.69 -4.31 -1.23 -3.05 4.21 5.09 2.28 1.34
        1
        0.01 0.01 -0.04 -0.05 -0.07 0.01 -0.05 0.04 0.14 -0.02 -0.04
        GM.5.0.Forkhead.0030
        FOXA2,FOXA3,FOXA1,FOXD1,FOXF1, (...)
        -2.73 -0.12 -0.86 -2.63 -1.11 -3.30 -1.43 -1.07 5.06 0.12 0.61
        <1
        -0.05 -0.02 -0.03 -0.03 -0.02 -0.00 -0.02 -0.02 0.16 0.02 -0.01
        GM.5.0.ARID_BRIGHT.0002
        ARID5A,HMGA1A
        1.45 2.71 -1.02 -0.69 -1.39 -2.17 0.53 3.01 1.42 -2.04 -2.96
        <1
        0.05 0.01 -0.03 -0.01 -0.04 0.00 0.00 0.04 0.05 -0.06 -0.06
        GM.5.0.CBF_NF-Y.0002
        NFYC,NFYBA,NFYBB,NFYA,NFYAL, (...)
        2.38 5.81 -0.91 -0.28 -2.01 3.39 -1.58 -2.38 0.86 -4.61 -5.39
        1
        0.03 0.04 -0.01 -0.02 -0.03 0.05 -0.02 -0.01 0.07 -0.06 -0.07
        GM.5.0.bHLH.0135
        LYL1,TFAP4,TAL1,NHLH2,SIN3AA, (...)
        -2.09 0.04 -0.88 5.25 0.79 -2.60 3.58 1.22 -0.77 -0.24 -0.55
        2
        0.04 -0.03 -0.04 0.06 -0.00 -0.04 0.03 -0.01 0.03 -0.04 -0.03
        GM.5.0.Homeodomain_POU.0011
        POU3F2B,POU3F2A,POU3F3B,POU3F1,POU3F3A, (...)
        -0.34 -0.34 -1.09 -0.39 -3.32 -0.80 -0.05 2.41 0.19 -1.96 -0.04
        <1
        0.08 -0.03 -0.03 -0.00 -0.06 0.03 0.01 0.03 0.05 -0.06 -0.06
        GM.5.0.Prospero.0001
        PROX2,PROX1A
        2.30 0.30 2.16 1.87 -2.21 -0.70 2.74 1.26 -5.41 -1.12 0.34
        2
        0.06 -0.02 -0.00 0.02 -0.05 0.01 0.05 0.03 -0.01 -0.06 -0.06
        GM.5.0.STAT.0008
        STAT3,NO ORTHOLOGS FOUND,STAT1B,STAT4,STAT2, (...)
        1.76 -3.28 1.13 3.29 -0.39 0.58 2.40 -3.05 0.51 -0.93 -1.44
        1
        0.11 -0.11 -0.01 0.07 -0.01 0.01 0.08 -0.04 -0.01 -0.07 -0.06
        GM.5.0.Nuclear_receptor.0025
        AR,PGR,NR3C1,NR3C2,NO ORTHOLOGS FOUND, (...)
        -0.58 -0.60 -0.46 1.30 0.15 3.28 -0.53 -0.12 0.60 -0.79 -0.93
        2
        0.02 -0.04 -0.01 0.03 0.01 0.02 0.01 -0.03 0.04 -0.02 -0.03
        GM.5.0.bZIP.0051
        XBP1,SIM1A,HIF1AB,NPAS3B,NPAS3, (...)
        -0.70 3.12 0.33 -2.18 -1.27 -0.59 0.50 0.46 -0.12 1.24 -0.19
        2
        -0.01 0.03 0.00 -0.04 -0.04 0.03 0.02 0.03 0.05 -0.03 -0.04
        GM.5.0.CUT_Homeodomain.0004
        CUX2B,CUX1B,CUX1A,PBX4,PBX1A, (...)
        -2.12 3.15 -1.24 -0.29 -0.20 1.41 -1.27 2.36 0.97 -0.37 -2.11
        <1
        0.01 0.02 -0.03 -0.03 -0.04 0.05 -0.03 0.02 0.07 -0.03 -0.05
        GM.5.0.Unknown.0025
        NO ORTHOLOGS FOUND,BPTF
        -0.61 0.32 -0.45 0.66 -1.16 1.30 1.41 1.29 3.31 -0.49 -0.71
        <1
        0.00 -0.02 -0.00 0.03 -0.03 -0.01 0.01 0.00 0.06 -0.03 -0.04
        GM.5.0.C2H2_ZF.0225
        SMAD9,SMAD1,SMAD5,NO ORTHOLOGS FOUND
        1.78 -3.68 0.73 0.85 2.88 0.37 -2.02 -3.42 -0.94 -0.30 1.21
        2
        0.10 -0.10 -0.00 0.05 0.05 -0.02 0.02 -0.07 -0.04 -0.01 -0.00
        GM.5.0.Unknown.0145
        SRFA,SRFB,NO ORTHOLOGS FOUND
        -0.94 0.85 -1.32 -0.90 3.14 1.49 0.99 -0.46 -0.60 0.58 2.01
        1
        0.01 -0.03 -0.02 -0.01 0.01 0.01 0.02 0.01 0.04 -0.03 -0.03
        GM.5.0.Homeodomain.0047
        GATA1A,GATA1B,GATA2A,GATA3,SIX1B, (...)
        -2.58 -2.23 -3.32 -2.88 4.05 -3.90 -0.27 0.70 3.20 3.30 0.32
        2
        -0.01 -0.04 -0.04 -0.05 0.04 -0.05 0.03 0.03 0.06 0.04 -0.03
        GM.5.0.Myb_SANT.0008
        MYB,SI_DKEY-17E16.13,OVOL1,MYBL2B,MYBL1, (...)
        -2.42 -0.53 -3.17 0.80 -3.27 2.51 3.32 0.33 4.20 -2.33 -3.71
        <1
        -0.03 -0.01 -0.04 -0.01 -0.07 0.07 0.05 0.03 0.12 -0.05 -0.06
        GM.5.0.Mixed.0028
        THAP1,THAP3,YY1A,YY1B,NO ORTHOLOGS FOUND
        -1.26 2.17 -1.40 -0.82 -0.39 -2.29 2.29 4.23 -2.03 -2.09 -0.65
        1
        0.05 -0.03 -0.01 -0.01 -0.02 -0.01 0.02 0.04 0.04 -0.05 -0.04
        GM.5.0.Mixed.0076
        PAX8,PAX6B,PAX6A,PAX2B,PAX2A, (...)
        -2.34 0.66 -1.04 -0.03 -0.89 4.70 1.68 0.70 0.60 0.42 -0.29
        2
        -0.04 -0.01 -0.00 -0.03 -0.04 0.10 0.00 0.00 0.04 -0.00 -0.02
        GM.5.0.bHLH.0137
        NEUROD4,NEUROD1,NEUROD6B,TCF3B,ATOH1A, (...)
        5.17 -2.49 -2.88 -2.18 -1.56 -3.57 -1.36 2.53 -1.02 -1.09 0.18
        2
        0.13 -0.07 -0.03 0.02 0.00 -0.04 -0.00 -0.02 0.02 -0.03 -0.03
        GM.5.0.C2H2_ZF.0179
        HIC1
        2.80 -2.64 1.36 -2.99 2.06 -1.34 -3.05 0.37 -1.82 0.19 0.85
        1
        0.08 -0.07 0.02 -0.03 0.03 -0.01 -0.04 -0.01 0.01 -0.01 -0.01
        GM.5.0.C2H2_ZF.0213
        GLI3,GLI2B,GLI2A,GLI1,LOC108179203, (...)
        -2.17 1.15 2.42 -0.04 0.94 0.30 -0.47 -1.61 -1.36 3.19 1.92
        3
        -0.03 0.00 0.03 0.01 0.04 -0.01 -0.02 -0.06 -0.03 0.06 0.04
        GM.5.0.C2H2_ZF.0162
        YY1A,YY1B,MBTPS2,TAF1,MYCB, (...)
        3.64 -0.65 -2.14 -1.09 -0.80 -1.64 -0.40 2.78 -1.07 -1.68 -1.33
        1
        0.10 -0.05 -0.03 -0.01 -0.01 -0.01 -0.00 0.02 0.03 -0.05 -0.04
        GM.5.0.Mixed.0024
        SP7,DLX5A
        0.43 -0.53 1.40 -3.03 -1.19 -1.66 -0.31 1.23 -0.28 0.12 0.90
        1
        0.05 -0.03 -0.01 -0.03 -0.01 0.02 -0.01 0.01 0.02 -0.02 -0.02
        GM.5.0.MADS_box.0002
        MEF2AA,MEF2CA,MEF2CB,MEF2AB,MEF2D, (...)
        0.78 -3.75 -3.18 2.21 5.94 -3.09 3.23 -2.77 -0.87 -2.67 -4.80
        2
        0.07 -0.03 -0.04 -0.00 0.06 -0.02 0.03 0.01 0.02 -0.06 -0.07
        GM.5.0.Nuclear_receptor.0123
        HNF4A,HDAC1
        -4.18 -1.18 -3.58 0.89 0.19 2.63 1.57 -0.45 3.31 3.07 3.35
        <1
        -0.11 -0.07 -0.07 -0.01 -0.02 0.10 0.00 -0.02 0.17 0.03 0.00
        GM.5.0.TEA.0006
        TEAD1B,NO ORTHOLOGS FOUND,TEAD3B,LOC101887189,TEAD1A, (...)
        -0.29 0.44 3.24 1.69 3.02 -0.50 0.43 -2.16 -0.98 -1.01 -1.40
        1
        0.03 -0.04 0.04 0.03 0.02 0.00 0.00 -0.03 0.00 -0.04 -0.04
        GM.5.0.GATA.0024
        GATA1A,NO ORTHOLOGS FOUND,GATA2A,GATA1B,GATA3
        1.11 -2.99 3.47 -0.52 -0.47 0.36 -1.15 -1.31 -0.52 -0.78 0.13
        2
        0.03 -0.06 0.03 -0.00 -0.02 0.03 -0.00 -0.00 0.05 -0.04 -0.04
        GM.5.0.Homeodomain.0044
        PITX3,PITX1,PITX2,DRGX,DHARMA, (...)
        3.13 0.05 0.78 -1.41 -0.37 -2.00 -1.48 0.72 -1.34 1.84 0.52
        1
        0.07 -0.03 -0.02 -0.03 -0.00 -0.01 -0.02 0.01 0.02 0.00 -0.02
        GM.5.0.bHLH.0084
        TAL1,GATA4
        0.76 -1.15 -1.92 -1.65 1.99 -2.97 0.48 -0.98 0.16 3.48 0.35
        2
        0.06 -0.06 -0.04 -0.01 0.04 -0.05 0.04 -0.01 0.02 0.01 -0.03
        GM.5.0.Paired_box.0001
        PAX8,PAX1B,PAX9,PAX1A,PAX5, (...)
        0.02 -2.41 -2.01 -2.23 -0.90 5.25 -2.12 -0.37 -3.00 0.05 1.62
        1
        0.04 -0.04 -0.01 -0.02 -0.01 0.09 -0.01 -0.01 0.00 -0.02 -0.03
        GM.5.0.Nuclear_receptor.0059
        RARAB,RARGB,RARAA,RARGA,RORB, (...)
        -4.33 0.86 -1.36 1.20 0.46 3.51 0.67 -0.69 1.85 0.03 -1.24
        2
        -0.09 -0.05 -0.05 -0.01 0.00 0.09 0.03 -0.02 0.13 0.00 -0.02
        GM.5.0.Unknown.0012
        NO ORTHOLOGS FOUND,KLF5B,PLAG1,KLF17,KLF5A, (...)
        1.69 -1.30 -0.82 0.78 0.99 -1.72 0.11 0.03 -3.41 -1.93 -1.83
        1
        0.11 -0.03 -0.02 0.01 -0.01 0.00 0.03 0.01 -0.00 -0.09 -0.07
        GM.5.0.bHLH.0048
        NEUROD6B,NEUROD4,NEUROD1,NEUROD2,TCF15, (...)
        4.83 -2.13 0.53 4.47 -2.11 -5.23 -2.58 -2.87 -4.23 1.76 0.57
        1
        0.09 -0.06 -0.01 0.06 0.00 -0.07 -0.01 -0.03 -0.01 -0.00 -0.01
        GM.5.0.bHLH.0028
        TCF3B,TCF12,TCF4,MYOD1,MYF5, (...)
        -1.64 -1.44 -1.59 5.03 0.22 -2.82 3.66 -1.18 1.07 -1.73 -2.96
        2
        0.03 -0.05 -0.02 0.06 0.00 -0.03 0.02 -0.03 0.03 -0.02 -0.03
        GM.5.0.Unknown.0079
        RXRAB,RXRBB,RXRGB,RXRBA,RXRGA, (...)
        1.26 2.42 -1.34 -2.96 1.91 -0.78 -2.80 -3.11 -0.15 2.57 2.40
        <1
        -0.02 -0.06 -0.06 -0.01 0.03 0.06 0.01 -0.05 0.10 0.01 -0.01
        GM.5.0.GATA.0026
        TFAP2A,TFAP2D,TFAP2E,TFAP2C,TFAP2B, (...)
        1.88 -3.65 4.55 0.43 0.04 1.71 -0.84 -3.13 -2.85 0.22 -0.82
        1
        0.07 -0.10 0.03 0.02 0.02 0.03 -0.00 -0.03 0.01 -0.03 -0.03
        GM.5.0.Homeodomain.0079
        ZNF384L,PBX1A,PBX3B,FOXP4,AHCTF1, (...)
        0.81 0.99 -0.24 -1.48 -2.82 -0.75 0.17 3.88 2.38 -1.59 -1.36
        2
        0.06 -0.02 -0.04 0.01 -0.07 0.00 0.03 0.05 0.08 -0.08 -0.07
        GM.5.0.MADS_box.0019
        MEF2AA,MEF2CA,MEF2CB,MEF2AB,JUN, (...)
        -1.16 0.99 -0.64 2.70 -0.34 2.46 3.40 -1.11 -0.35 -1.36 -2.45
        2
        0.04 -0.07 -0.03 0.07 -0.04 0.05 0.10 -0.02 0.02 -0.07 -0.07
        GM.5.0.Unknown.0090
        NR4A1,NR4A2B,LOC103911606,NR2F1B,NR2F2, (...)
        -1.57 -1.32 -3.45 -1.47 0.58 2.72 -2.15 -1.34 2.42 2.25 3.37
        2
        -0.13 -0.07 -0.08 -0.03 -0.01 0.10 -0.01 -0.03 0.19 0.06 0.02
        GM.5.0.Ets.0003
        FEV,ETS2,ERF,ERFL3,ETS1, (...)
        -4.59 -1.49 -4.70 4.66 -4.34 3.43 5.79 1.84 1.10 -3.57 -4.38
        2
        -0.04 -0.05 -0.06 0.10 -0.09 0.07 0.19 0.02 0.05 -0.09 -0.10
        GM.5.0.Nuclear_receptor.0006
        NR1D1,NR1D2A,NR1D4B,NR1D4A,NR1D2B, (...)
        0.33 -3.23 -2.37 -1.00 -0.07 -0.73 -2.02 -0.51 2.45 2.25 1.11
        2
        -0.04 -0.06 -0.04 -0.02 0.01 0.06 -0.00 -0.02 0.12 0.00 -0.02
        GM.5.0.Sox.0029
        TCF7,TCF7L2,TCF7L1A,TCF7L1B,LEF1, (...)
        1.99 -1.36 -0.70 -3.92 -2.09 -2.31 -3.84 -0.60 3.33 2.34 2.77
        2
        0.03 -0.06 -0.04 -0.02 -0.05 0.03 -0.01 0.00 0.11 -0.01 -0.02
        GM.5.0.GATA.0005
        GATA1A,GATA1B,GATA2A,GATA3,GATA6, (...)
        -5.76 -4.33 -4.61 -3.82 4.70 -4.78 4.67 4.00 4.39 4.57 -2.49
        <1
        -0.03 -0.06 -0.06 -0.06 0.05 -0.05 0.04 0.05 0.08 0.06 -0.02
        GM.5.0.Unknown.0198
        NFIA,NFIXB,LOC103909284,NFIC,NO ORTHOLOGS FOUND, (...)
        -1.66 -2.49 0.03 0.18 2.22 -0.45 -3.41 -2.20 3.43 1.78 0.51
        2
        -0.00 -0.06 -0.01 0.00 0.01 -0.00 -0.04 -0.02 0.10 0.01 -0.01
        GM.5.0.bHLH.0049
        ETV7,MXI1,EF1,MAX,NO ORTHOLOGS FOUND, (...)
        -1.78 -0.87 -0.56 2.78 -2.18 3.56 2.99 -0.22 1.57 -1.55 -3.07
        2
        -0.01 -0.08 -0.03 0.08 -0.05 0.06 0.15 -0.01 0.02 -0.06 -0.07
        GM.5.0.Nuclear_receptor.0093
        HNF4A,NR2C1,NR2C2,PPARAB,NR2F1A, (...)
        -3.62 -0.14 -2.17 -0.93 1.26 2.48 -0.57 -0.11 2.16 3.64 3.09
        2
        -0.13 -0.08 -0.06 -0.03 0.00 0.10 -0.02 -0.03 0.16 0.06 0.03
        GM.5.0.C2H2_ZF.0156
        PRDM6,CUX1B,CUX1A,PTF1A,BCL6B
        3.20 -1.85 2.51 3.23 2.08 1.35 -0.21 0.06 -3.29 -4.36 -1.90
        1
        0.16 -0.10 -0.02 0.09 -0.00 -0.01 0.08 -0.02 -0.03 -0.12 -0.09
        GM.5.0.STAT.0021
        HDX,STAT3,STAT1B,STAT4,STAT2, (...)
        2.13 -0.76 -0.84 2.04 -3.04 -0.04 -1.04 2.43 2.74 -3.58 -2.16
        <1
        0.10 -0.08 -0.04 0.05 -0.07 0.04 0.07 -0.00 0.07 -0.10 -0.10
        GM.5.0.Ets.0033
        FEV,EF1,ETV1,ELF3,ETV5A, (...)
        -3.40 -3.49 0.35 4.59 -0.58 3.38 4.81 -3.15 -2.19 0.68 -0.53
        2
        -0.02 -0.09 -0.03 0.09 -0.04 0.06 0.14 -0.03 0.02 -0.05 -0.06
        GM.5.0.Nuclear_receptor.0031
        ESRRGB,ESRRA,ESRRB,ESRRGA,NR5A1B, (...)
        -0.85 1.44 -3.13 -1.69 1.85 0.85 1.16 -2.26 2.45 -1.69 -0.93
        2
        -0.08 -0.06 -0.06 -0.03 0.00 0.09 0.01 -0.03 0.14 0.02 -0.01
        GM.5.0.Rel.0020
        STAT6,STAT5A,STAT5B,NFATC4,NFATC2A, (...)
        3.35 0.36 -0.68 1.45 1.06 -0.82 -0.97 -0.97 -0.18 -1.27 -2.17
        1
        0.08 -0.03 -0.03 0.04 -0.03 0.02 0.00 0.00 0.03 -0.07 -0.06
        GM.5.0.TEA.0007
        TEAD1B,TEAD3B,LOC101887189,TEAD1A,TEAD3A, (...)
        -2.73 0.95 4.02 3.38 4.42 3.81 -1.42 -5.16 0.15 -1.44 -1.45
        2
        -0.00 -0.05 0.04 0.06 0.03 0.05 0.02 -0.05 0.01 -0.05 -0.05
        GM.5.0.RFX.0002
        RFX5,TBPL2,NELFE,LOC100538179,RFX7, (...)
        3.60 -0.07 -0.77 -0.11 0.34 0.27 -2.07 -1.03 -1.90 -0.95 -1.78
        1
        0.10 -0.01 -0.01 -0.00 -0.01 0.01 -0.02 -0.01 -0.00 -0.04 -0.04
        GM.5.0.SMAD.0006
        NFIA,NFIXB,LOC103909284,TLX1,NFIC, (...)
        3.10 -4.22 1.78 0.40 4.76 -2.43 -2.19 -3.12 -0.07 -1.25 -2.91
        2
        0.08 -0.09 0.00 0.00 0.05 -0.00 -0.02 -0.03 0.05 -0.05 -0.05
        GM.5.0.bZIP.0016
        ATF1,CREB1B,CREB1A,CREMA,CREB5B, (...)
        -0.02 1.92 2.74 0.72 0.94 0.68 -0.61 -1.92 -1.15 -3.44 -3.55
        2
        -0.02 0.01 0.01 -0.01 -0.04 0.05 0.01 0.01 0.08 -0.05 -0.06
        GM.5.0.RFX.0005
        RFX3,RFX1A,RFX2,RFX1B,LOC100538179, (...)
        4.53 -0.77 0.24 -0.80 -0.94 1.51 -2.66 1.07 -0.34 -1.33 -1.20
        1
        0.08 -0.02 -0.02 -0.02 -0.03 0.04 -0.02 0.01 0.02 -0.05 -0.05
        GM.5.0.bZIP.0052
        CEBPA,CEBPZ,CEBPB,HNF4A,CEBPG, (...)
        -2.60 -4.26 3.26 -2.49 -4.03 2.01 3.55 -4.57 4.56 0.92 0.47
        2
        0.01 -0.08 0.03 -0.01 -0.06 0.05 0.01 -0.03 0.12 -0.02 -0.04
        GM.5.0.Nuclear_receptor.0048
        AR,PGR,NR3C1,NR3C2,PRDM15, (...)
        0.51 -1.61 2.36 0.00 2.86 2.93 -1.52 -3.13 -0.92 1.21 -0.74
        2
        -0.01 -0.06 -0.00 0.01 0.02 0.05 -0.00 -0.04 0.04 0.00 -0.03
        GM.5.0.bZIP.0096
        CREB1B,CREMA,ATF1,CREB1A,ATF7A, (...)
        -1.02 -2.10 2.33 3.50 1.77 0.05 0.38 -3.22 1.31 -3.62 -3.37
        3
        0.00 -0.01 0.01 0.01 -0.02 0.03 0.01 -0.01 0.06 -0.05 -0.06
        GM.5.0.Mixed.0080
        NO ORTHOLOGS FOUND,ZEB1B,PAX2B,ZEB2B,PAX2A, (...)
        0.56 0.59 0.74 1.84 1.04 0.24 0.92 -1.91 -3.46 1.55 0.79
        <1
        0.06 -0.07 -0.04 0.03 -0.05 0.03 0.04 -0.01 0.10 -0.06 -0.07
        GM.5.0.Homeodomain.0186
        HNF1A,HNF1BA
        -4.76 -3.69 -5.22 -5.13 -5.35 6.09 -6.09 -2.00 4.30 1.38 1.25
        3
        -0.05 -0.02 -0.08 -0.08 -0.09 0.25 -0.07 0.00 0.13 0.01 -0.01
        GM.5.0.bZIP.0013
        JUN,FOSB,FOSAB,FOSAA,SI_CH211-153J24.3, (...)
        2.45 -4.02 3.71 2.86 0.11 2.73 -4.22 -4.53 -2.71 2.46 0.90
        3
        0.05 -0.06 0.04 0.02 -0.01 0.05 -0.03 -0.06 -0.02 0.01 -0.01
        GM.5.0.Ets.0010
        ETS2,EF1,ELF3,ERF,EHF, (...)
        -1.17 -3.31 -1.31 2.29 -4.96 4.35 5.79 -1.49 -0.26 -1.43 -3.33
        3
        0.07 -0.11 -0.04 0.10 -0.04 0.04 0.20 -0.04 -0.02 -0.09 -0.08
        GM.5.0.Paired_box.0005
        IRF4B,IRF10,PAX5,IRF8,IRF4A, (...)
        4.05 -2.51 -0.10 1.11 0.30 -0.26 0.93 -3.99 0.64 -1.08 -1.57
        4
        0.16 -0.10 -0.02 0.07 0.03 -0.03 0.08 -0.07 -0.06 -0.06 -0.04
        GM.5.0.Nuclear_receptor.0028
        HNF4A,PPARAB,PPARDB,PPARDA,PPARG, (...)
        -5.64 -4.88 -4.99 -4.86 -4.66 4.51 -5.41 -3.88 5.94 5.94 4.75
        2
        -0.14 -0.10 -0.09 -0.05 -0.03 0.12 -0.04 -0.04 0.23 0.10 0.05
        GM.5.0.Rel.0018
        NO ORTHOLOGS FOUND,SI_CH211-166G5.4,LOC100535691,VEZF1B,VEZF1A, (...)
        4.35 -2.56 0.85 0.94 0.85 -1.69 0.56 -0.94 -1.74 -2.91 -0.43
        2
        0.19 -0.11 -0.01 0.06 0.03 -0.04 0.08 -0.06 -0.07 -0.08 -0.05
        GM.5.0.bZIP.0009
        HLFA,NO ORTHOLOGS FOUND,HLFB,TEFA,TEFB, (...)
        2.12 -4.06 -1.01 -1.07 -0.75 3.49 -4.10 -4.84 2.78 1.05 3.20
        3
        0.01 -0.03 0.01 -0.03 -0.04 0.05 -0.02 -0.02 0.08 -0.00 -0.03
        GM.5.0.IRF.0011
        NO ORTHOLOGS FOUND,EZH2,BCL11BA,EF1,IM_7142702, (...)
        4.16 -2.67 -1.87 2.16 1.09 -0.66 -1.29 -2.50 1.22 -2.80 -2.79
        3
        0.17 -0.11 -0.03 0.09 0.00 -0.03 0.10 -0.05 -0.05 -0.10 -0.06
        GM.5.0.C2H2_ZF.0037
        CTCF,SMC3,RAD21A,RAD21B,PPARGC1A, (...)
        3.80 0.53 -5.15 -0.30 0.05 3.67 2.43 -3.38 5.12 -5.46 -4.62
        3
        0.07 -0.03 -0.07 -0.02 -0.02 0.03 0.02 -0.00 0.09 -0.07 -0.06
        GM.5.0.Unknown.0124
        HLTF
        0.09 -2.52 -3.01 -0.20 -1.20 0.81 1.80 1.51 1.02 0.57 0.38
        <1
        0.02 -0.07 -0.03 0.00 -0.02 0.03 0.03 0.01 0.06 -0.02 -0.04
        GM.5.0.RFX.0018
        LOC100538179,RFX5,RFX7,RFX6,RFX1B, (...)
        6.09 1.73 -1.37 -3.27 -0.88 -1.32 -5.25 -2.33 -3.36 -0.98 0.60
        3
        0.12 0.02 -0.00 -0.02 -0.02 -0.01 -0.04 -0.00 -0.01 -0.04 -0.03
        GM.5.0.GATA.0014
        NO ORTHOLOGS FOUND,GATA3,RREB1A,GATA1B,RREB1B, (...)
        2.26 -0.39 -2.00 3.27 2.38 2.14 -2.52 -5.55 -3.65 4.07 4.68
        <1
        -0.03 0.03 0.02 0.04 0.06 -0.05 -0.04 -0.10 -0.10 0.10 0.11

        Samples & Config

        The samples file used for this run:

        sample assembly biological_replicates descriptive_name
        GSM4661979 danRer10 Brain Brain_rep1
        GSM4661980 danRer10 Brain Brain_rep2
        GSM4661981 danRer10 Brain Brain_rep3
        GSM4661998 danRer10 Testis Testis_rep1
        GSM4661999 danRer10 Testis Testis_rep2
        GSM4661994 danRer10 Skin Skin_rep1
        GSM4661995 danRer10 Skin Skin_rep2
        GSM4661992 danRer10 Muscle Muscle_rep1
        GSM4661993 danRer10 Muscle Muscle_rep2
        GSM4661984 danRer10 Heart Heart_rep1
        GSM4661985 danRer10 Heart Heart_rep2
        GSM4661988 danRer10 Kidney Kidney_rep1
        GSM4661989 danRer10 Kidney Kidney_rep2
        GSM4661996 danRer10 Spleen Spleen_rep1
        GSM4661997 danRer10 Spleen Spleen_rep2
        GSM4661977 danRer10 Blood Blood_rep1
        GSM4661978 danRer10 Blood Blood_rep2
        GSM4661990 danRer10 Liver Liver_rep1
        GSM4661991 danRer10 Liver Liver_rep2
        GSM4661986 danRer10 Intestine Intestine_rep1
        GSM4661987 danRer10 Intestine Intestine_rep2
        GSM4661982 danRer10 Colon Colon_rep2
        GSM4661983 danRer10 Colon Colon_rep1

        The config file used for this run:
        # tab-separated file of the samples
        samples: samples.tsv
        
        # pipeline file locations
        result_dir: ./results  # where to store results
        genome_dir: ./genomes  # where to look for or download the genomes
        # fastq_dir: ./results/fastq  # where to look for or download the fastqs
        
        
        # contact info for multiqc report and trackhub
        email: yourmail@here.com
        
        # produce a UCSC trackhub?
        create_trackhub: true
        
        # how to handle replicates
        biological_replicates: fisher  # change to "keep" to not combine them
        technical_replicates: merge    # change to "keep" to not combine them
        
        # which trimmer to use
        trimmer: fastp
        
        # which aligner to use
        aligner: bwa-mem2
        
        # filtering after alignment
        remove_blacklist: true
        remove_mito: true
        tn5_shift: true
        min_mapping_quality: 30
        only_primary_align: true
        max_template_length: 150
        remove_dups: true
        
        # should the final output be stored as cram files (instead of bam) to save storage?
        store_as_cram: false
        
        # macs2 ignores the mates in a paired sequencing sample. with this option enabled
        # seq2science removes the mate information after alignment, so all reads are used
        macs2_keep_mates: true
        
        # peak callers (supported peak callers are macs2, and genrich)
        peak_caller:
          macs2:
              --shift -100 --extsize 200 --nomodel --buffer-size 10000
        #  genrich:
        #      -j -y -D -d 200 -q 0.05
        
        # how much peak summits will be extended by (on each side) for the final count table
        # (e.g. 100 means a 200 bp wide peak)
        slop: 100
        
        # whether or not to run gimme maelstrom to infer differential motifs
        run_gimme_maelstrom: true
        
        # differential accessibility analysis
        # for explanation, see: https://vanheeringen-lab.github.io/seq2science/content/DESeq2.html
        #contrasts:
        #  - 'biological_replicates_dome_sphere'