824566
doi
10.5281/zenodo.824566
oai:zenodo.org:824566
A.S.M. Monjur-Al-Hossain
Department of Pharmaceutical Technology, University of Dhaka, Dhaka-1000, Bangladesh
Subarna Saha
Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh
Samir Kumar Sadhu
Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh
Assessment of Biological Activity on Cirsium arvense L.
Md. Lokman Hossain
Department of Pharmacy, Stamford University Bangladesh, Dhaka-1217, Bangladesh
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Cirsium arvense
Antibacterial
Cytotoxicity
Anthlemintic
Anti-hyperglycemic
<p>This study was aimed at evaluating antibacterial, cytotoxic, anthelmintic and anti-hyperglycemic activity of aerial part of <em>Cirsium arvense</em>. Antibacterial activity was determined by disc diffusion method at the concentration of 200, 250 and 500 µg/disc. Cytotoxic and anthelmintic activity was carried out according to Meyer and Gade method with slight modification respectively. The anti-hyperglycemic activity was determined by the method followed by Djilani. The extract showed dose dependent antibacterial activity against the experimental bacterial strains except <em>Staphylococcus epidermidi</em>, <em>Streptococcus agalactiae</em> and <em>Enterococcus faecalis</em>. In brine shrimp lethality bioassay, it showed LC<sub>50</sub> at 51 µg/ml that is comparable to that of standard drug, vincristine sulphate (LC<sub>50</sub> 0.44 µg/ml). Also it showed dose dependent anthelmintic activity. It did not show anti-hyperglycemic activity. Our findings provide evidence that potential bioactive compounds are responsible for biological activities and further studies are required to isolate these compounds.</p>
Zenodo
2017-07-08
info:eu-repo/semantics/article
824565
1579541536.377306
549858
md5:de43d084cb1c16fc7fcd53ff3039ac23
https://zenodo.org/records/824566/files/AJNP-2017-01_final.pdf
public
10.5281/zenodo.824565
isVersionOf
doi
Algerian Journal of Natural Products
5
1
417- 426
2017-07-08