Characterization and Evaluation of Saururus cernuus Emulgel for Antibacterial Activity - Parul Nigam; Sonam Mishra (Zenodo, 2023)
Abstract: The purpose of this research was to characterize and evaluate a topical Emulgel formulation derived from Saururus cernuus, a plant known for its antibacterial properties. The plant was collected, and the extractive values were determined. Phytochemical analysis confirmed the presence of flavonoids and tannins, bioactive compounds that exhibit antibacterial activity. The Emulgel formulation was prepared and thoroughly analyzed for parameters such as pH, viscosity, and spreadability. An in vitro drug release study showcased a sustained release profile of the active components, ensuring prolonged antibacterial activity. The antibacterial effectiveness of the Emulgel was validated against Staphylococcus aureus and Escherichia coli using the disc diffusion method, demonstrating broad-spectrum antibacterial potential. Across all tests, the formulation exhibited consistency, suggesting robustness in the formulation process. While the results are promising, further in vivo studies are recommended to confirm the formulation's efficacy and safety on actual skin conditions.
Keywords: cc-by-4.0; Saururus cernuus; Emulgel; Antibacterial Activity; Topical Formulation; Disc Diffusion Method; Phytochemical Analysis