Journal article Open Access

A Review Novel on Synthesis of Triazole and Chemistry of Active Chemical Moiety

Soubin Roy; Santosh Dattu Navale; Sumit Shivaji Misal

ABSTRACT

The triazoles possess wide spectrum of biological activities like including antibacterial, antifungal, antiviral, anti-inflammatory, anticonvulsant, antidepressant, antihypertensive, analgesic, and hypoglycemic properties. The present reviews attempted to gather the basic developments in synthesis and biological activities of triazole derivatives. The novel chemical moiety used in medicinal active substance either (R) or (L) hence Dextro or Levo rotatory form. The broad spectrum of activity is due nitrogen hence nitrogen containing loan pair of electron transfer to another substance and formation of covalent bond.

Keywords Pharmacological activity, Triazole, Synthesis, Isomers, Bio conjugation

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