Journal article Open Access

FORMULATION AND DEVELOPMENT OF ESOMEPRAZOLE MAGNESIUM TRIHYDRATE ORO-DISPERSIBLE TABLETS

K. Vinod Kumar*, S. Manohar Babu., T. Srinivas, B. Gopi, G. Sravani, M. Rajesh, P. Susanna, Sk. Aathika, Sk. Waseem.


JSON Export

{
  "files": [
    {
      "links": {
        "self": "https://zenodo.org/api/files/2d7046e9-af98-4b8e-bc9e-5d6067c85f3c/63.pharmaceutics%20project-Research%20article%20edited%20%20document.pdf"
      }, 
      "checksum": "md5:0b5659a71ffc23f1849b552c4133bfe1", 
      "bucket": "2d7046e9-af98-4b8e-bc9e-5d6067c85f3c", 
      "key": "63.pharmaceutics project-Research article edited  document.pdf", 
      "type": "pdf", 
      "size": 1069188
    }
  ], 
  "owners": [
    159385
  ], 
  "doi": "10.5281/zenodo.6943933", 
  "stats": {
    "version_unique_downloads": 10.0, 
    "unique_views": 18.0, 
    "views": 18.0, 
    "version_views": 18.0, 
    "unique_downloads": 10.0, 
    "version_unique_views": 18.0, 
    "volume": 10691880.0, 
    "version_downloads": 10.0, 
    "downloads": 10.0, 
    "version_volume": 10691880.0
  }, 
  "links": {
    "doi": "https://doi.org/10.5281/zenodo.6943933", 
    "conceptdoi": "https://doi.org/10.5281/zenodo.6943932", 
    "bucket": "https://zenodo.org/api/files/2d7046e9-af98-4b8e-bc9e-5d6067c85f3c", 
    "conceptbadge": "https://zenodo.org/badge/doi/10.5281/zenodo.6943932.svg", 
    "html": "https://zenodo.org/record/6943933", 
    "latest_html": "https://zenodo.org/record/6943933", 
    "badge": "https://zenodo.org/badge/doi/10.5281/zenodo.6943933.svg", 
    "latest": "https://zenodo.org/api/records/6943933"
  }, 
  "conceptdoi": "10.5281/zenodo.6943932", 
  "created": "2022-07-30T13:36:42.325353+00:00", 
  "updated": "2022-07-30T13:48:38.118479+00:00", 
  "conceptrecid": "6943932", 
  "revision": 2, 
  "id": 6943933, 
  "metadata": {
    "access_right_category": "success", 
    "doi": "10.5281/zenodo.6943933", 
    "description": "<p><em>Now-a-days the demand for mouth dissolving tablets has been rapidly increasing, especially for gediatric and pediatric patients who have swallowing difficulties. Esomeprazole is a Proton Pump Inhibitor used in the treatment of certain stomach and esophagus problems such as acid reflux, ulcers. In the present work, the &nbsp;Oro-dispersible tablets of esomeprazole &nbsp;by Direct Compression method using Superdisintegrants approach and effervescent approach. Bulk density, Tapped density, Compressibility index and Hauser&rsquo;s ratio are the powder &nbsp;flow properties evaluated for the final blend of drug and excipients. All the formulations were evaluated for thickness , weight variation , disintegration time , hardness , friability , drug content , water absorption ratio , and&nbsp; In-vitro dissolution studies. The lowest disintegration time and maximum in -vitro dissolution profile is performed by F6 formulation.</em></p>\n\n<p><strong><em>Keywords:</em></strong><em> Proton pump inhibitor, Oro-dispersible, Esomeprazole, Super disintegrates.</em></p>", 
    "license": {
      "id": "CC-BY-4.0"
    }, 
    "title": "FORMULATION AND DEVELOPMENT OF ESOMEPRAZOLE MAGNESIUM TRIHYDRATE ORO-DISPERSIBLE TABLETS", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "6943932"
          }, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "6943933"
          }
        }
      ]
    }, 
    "publication_date": "2022-07-30", 
    "creators": [
      {
        "name": "K. Vinod Kumar*, S. Manohar Babu., T. Srinivas, B. Gopi, G. Sravani, M. Rajesh, P. Susanna, Sk. Aathika, Sk. Waseem."
      }
    ], 
    "access_right": "open", 
    "resource_type": {
      "subtype": "article", 
      "type": "publication", 
      "title": "Journal article"
    }, 
    "related_identifiers": [
      {
        "scheme": "doi", 
        "identifier": "10.5281/zenodo.6943932", 
        "relation": "isVersionOf"
      }
    ]
  }
}
18
10
views
downloads
All versions This version
Views 1818
Downloads 1010
Data volume 10.7 MB10.7 MB
Unique views 1818
Unique downloads 1010

Share

Cite as