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PRELIMINARY INVESTIGATION OF BIOACTIVE CONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF ETHANOLIC EXTRACT OF AGAVE SISALANA

Apurva Pandya*, Ms. Priya Bisen, Dr. Manjeet Singh, Dr. Rajesh Mujoriya


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  <identifier identifierType="DOI">10.5281/zenodo.6893768</identifier>
  <creators>
    <creator>
      <creatorName>Apurva Pandya*, Ms. Priya Bisen, Dr. Manjeet Singh, Dr. Rajesh Mujoriya</creatorName>
    </creator>
  </creators>
  <titles>
    <title>PRELIMINARY INVESTIGATION OF BIOACTIVE CONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF ETHANOLIC EXTRACT OF AGAVE SISALANA</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2022</publicationYear>
  <dates>
    <date dateType="Issued">2022-07-24</date>
  </dates>
  <resourceType resourceTypeGeneral="JournalArticle"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/6893768</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.6893767</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;&lt;em&gt;Pyrexia or fever is caused as a secondary impact of infection, malignancy or other diseased states. It is the body&amp;#39;s natural defense to create an environment where infectious agent or damaged tissue cannot survive. &lt;/em&gt;&lt;em&gt;In present study, the antipyretic activity of ethanol extracts from Agave sisalana was evaluated using Brewer&amp;#39;s yeast induced pyrexia in rats. The results showed that the ethanolic extract of Agave sisalana possesses a significant antipyretic effect in maintaining normal body temperature and reducing yeast-induced elevated body temperature in rats in a dose dependent manner and its effect is comparable to that of the standard antipyretic drug paracetamol. &amp;nbsp;It was therefore concluded that the extracts of Agave sisalana demonstrated antipyretic activity, the ethanol extract was found to be potent than the aqueous extract. &lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Key words: &lt;/strong&gt;&lt;em&gt;Agave sisalana, Ethanolic extract, Antipyretic activity.&lt;/em&gt;&lt;/p&gt;</description>
  </descriptions>
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