Journal article Open Access

PRELIMINARY INVESTIGATION OF BIOACTIVE CONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF ETHANOLIC EXTRACT OF AGAVE SISALANA

Apurva Pandya*, Ms. Priya Bisen, Dr. Manjeet Singh, Dr. Rajesh Mujoriya


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{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.6893768", 
  "author": [
    {
      "family": "Apurva Pandya*, Ms. Priya Bisen, Dr. Manjeet Singh, Dr. Rajesh Mujoriya"
    }
  ], 
  "issued": {
    "date-parts": [
      [
        2022, 
        7, 
        24
      ]
    ]
  }, 
  "abstract": "<p><em>Pyrexia or fever is caused as a secondary impact of infection, malignancy or other diseased states. It is the body&#39;s natural defense to create an environment where infectious agent or damaged tissue cannot survive. </em><em>In present study, the antipyretic activity of ethanol extracts from Agave sisalana was evaluated using Brewer&#39;s yeast induced pyrexia in rats. The results showed that the ethanolic extract of Agave sisalana possesses a significant antipyretic effect in maintaining normal body temperature and reducing yeast-induced elevated body temperature in rats in a dose dependent manner and its effect is comparable to that of the standard antipyretic drug paracetamol. &nbsp;It was therefore concluded that the extracts of Agave sisalana demonstrated antipyretic activity, the ethanol extract was found to be potent than the aqueous extract. </em></p>\n\n<p><strong>Key words: </strong><em>Agave sisalana, Ethanolic extract, Antipyretic activity.</em></p>", 
  "title": "PRELIMINARY INVESTIGATION OF BIOACTIVE CONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF ETHANOLIC EXTRACT OF AGAVE SISALANA", 
  "type": "article-journal", 
  "id": "6893768"
}
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