Journal article Open Access

POLYMERS USED IN MOUTH DISSOLVING FORMULATIONS: A REVIEW

Aks*, Dr. Neelam Sharma, Shivani

Rapid advancement in the technology have developed a feasible dosage alternative for pediatrics from the oral route, geriatrics, non-compliant or queasy persons. Mouth dissolving formulations consist of ingredients such as API, polymers, saliva stimulating agents, preservative, flavors, sweetness, film stabilizing agents, surfactants, plasticizers etc. however, polymer is a pivotal ingredient which aid in film formation. Specifically hydrophilic polymers are used for film formation as they disintegrate quickly and have high bioavailability. These mouth dissolving formulations provide rapid, accurate dosing in a safe and efficacious manner, have better patient compliance. In this review article, the different polymers such as pullulan, sodium alginate, maltodextrin, starch, gelatin, pectin, polymerized rosin, Xanthan, HPMC, NaCMC, PVA, PVP, Kollicoat, polyethylene glycol, HPC, HEC, along with their properties and applications are highlighted.

Keywords: - Mouth dissolving films, Polymers, HPMC, Formulation, Applications

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