Journal article Open Access

DROSOPHILA MELANOGASTER – VERSATILE MODEL FOR THE STUDY OF HUMAN DISEASES

Rutuja S. Abhonkar *, Sagar R. Bagul


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    <subfield code="a">&lt;p&gt;&lt;em&gt;The fruit fly Drosophila Melanogaster is a popular model system in genetics labs that combines genetics and developmental biology. Drosophila genetics is tractable, but its embryonic development was too complex and intractable to study until molecular biology tools made gene manipulation and RNA extraction from these species possible. D. Melanogaster is quickly becoming one of the most powerful tools for studying the function of human disease genes, such as those involved in developmental and neurological disorders, cancer, cardiovascular disease, metabolic and storage diseases and genes involved in the visual, auditory and immune systems. Flies have various experimental benefits, including a fast life cycle and ability to create huge numbers of individuals, making them suitable for sophisticated genetic screening and in future aiding in the investigation of complicated disorders. This review considers the broad concept through which D. Melanogaster can be utilised to compare human disease, as well as its advantages and life cycle.&lt;/em&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;&lt;em&gt;Keywords: &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Drosophila Melanogaster, life cycle, Human disease model, Good model organism, Endocrinology of drosophila&lt;/em&gt;&lt;/p&gt;</subfield>
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