EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF SEBESTIANA CHAMELEA IN CHEMICALLY INDUCED HEPATOTOXIC RATS

The primary point and goals are assessment of the phytochemical screening of different concentrates of leaves of Sebestiana chamelea. Sebestiana chamelea is has a place with the Euphorbiaceae family. The primary point and targets are assessment of the phytochemical screening of different concentrates of leaves of Sebestiana chamelea. Assessment of the hepatoprotective action of different concentrates of leaves of Sebestiana chamelea in Carbon tetrachloride prompted hepatotoxicity in rodents. The various concentrates of the leaves of Sebestiana chamelea had promising hepatoprotective action against CCl4 instigated hepatic harm. The hepatoprotective movement of Sebestiana chamelea is found on a mission to be more in ethanolic extract.The action could be because of the improvement in the cell reinforcement protein level and a reduction in free extreme levels. The presence of phytochemicals, for example, flavonoids has been demonstrated to be liable for hepatoprotective activity.Further studies can be done in the future to explain the system of activity of the ethanolic concentrate of leaves of Sebestiana chamelea, which may then be followed and clinical examinations to lay out its viability in people.

KEY WORDS: Hepatoprotective activity, sebestiana chamelea leaves, albino rats