Journal article Open Access

REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY

Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar, Mr. Tanveer.Y. Shaikhb


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  <dc:creator>Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar,  Mr. Tanveer.Y. Shaikhb</dc:creator>
  <dc:date>2022-07-12</dc:date>
  <dc:description>The traditional dosage form has many limitations due to factors such as naso-lacrimal drainage &amp; shorter contact time. Ophthalmic in-situ gelling system composed of environmentally sensitive polymers that will be structurally changed in response to small changes in specific condition. Environmental pH, temperature, &amp; ionic strength, Response to environmental changes, the in- situ are liquids when installation into the eyes and then undergo rapidly gelation into the Cul- de-sac of the eye to form visco-elastic gel. This tends to increase ocular residence time and decreases Precorneal drug loss as a result. The goal of this study is to prepare and evaluate In- situ Gel for ocular drug delivery by using mucoadhesive polymers to increase ocular residence time and minimize Precorneal drugs loss of given formulation.

Keywords: Ocular Drug Delivery, In-situ Gelling System, Conjunctivitis.</dc:description>
  <dc:identifier>https://zenodo.org/record/6821620</dc:identifier>
  <dc:identifier>10.5281/zenodo.6821620</dc:identifier>
  <dc:identifier>oai:zenodo.org:6821620</dc:identifier>
  <dc:relation>doi:10.5281/zenodo.6821619</dc:relation>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>https://creativecommons.org/licenses/by/4.0/legalcode</dc:rights>
  <dc:title>REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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