Journal article Open Access

REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY

Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar, Mr. Tanveer.Y. Shaikhb


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{
  "description": "<p><em>The traditional dosage form has many limitations due to factors such as naso-lacrimal drainage &amp; shorter contact time. Ophthalmic in-situ gelling system composed of environmentally sensitive polymers that will be structurally changed in response to small changes in specific condition. Environmental pH, temperature, &amp; ionic strength, Response to environmental changes, the in- situ are liquids when installation into the eyes and then undergo rapidly gelation into the Cul- de-sac of the eye to form visco-elastic gel. This tends to increase ocular residence time and decreases Precorneal drug loss as a result. The goal of this study is to prepare and evaluate In- situ Gel for ocular drug delivery by using mucoadhesive polymers to increase ocular residence time and minimize Precorneal drugs loss of given formulation.</em></p>\n\n<p><strong>Keywords: </strong><em>Ocular Drug Delivery, In-situ Gelling System, Conjunctivitis.</em></p>", 
  "license": "https://creativecommons.org/licenses/by/4.0/legalcode", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain*, Dr. Sandip. R. Pawar,  Mr. Tanveer.Y. Shaikhb"
    }
  ], 
  "headline": "REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2022-07-12", 
  "url": "https://zenodo.org/record/6821620", 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.5281/zenodo.6821620", 
  "@id": "https://doi.org/10.5281/zenodo.6821620", 
  "@type": "ScholarlyArticle", 
  "name": "REVIEW OF NOVEL IN SITU GEL FOR OCULAR DRUG DELIVERY"
}
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